This is Jean-Claude Van Damme's fourth film where he plays a dual role after Double Impact (1991), Timecop (1994), and Maximum Risk (1996). In the same year he played dual roles for the fifth time as two characters from different time periods in The Order.
At the start of the movie, Van Damme lights a $20 bill on fire to ignite gasoline on a body. When he drops the bill, it has miraculously turned into a $1 bill.
This movie directly inspired "The Blacklist" episode 11, season 1, "The Good Samaritan".
Michael Rooker played a serial killer in Henry: Portrait of a Serial Killer (1986) years before playing the cop chasing the serial killer in Replicant.