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URL: https://da.wikipedia.org/wiki/Quetiapin

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Quetiapin

Fra Wikipedia, den frie encyklopædi
Quetiapin
Kliniske data
HandelsnavneAlzen, Seroquel, Stadaquel
AdministrationsvejPeroral
ATC-kode
Fysiologiske data
MetabolismeLever (CYP3A4)
Juridisk status
Juridisk status
  • DK: B
Farmakokinetiske data
Biotilgængelighed9%
MetabolismeLever (CYP3A4)
Halveringstid6 timer
UdskillelseUrin
Identifikatorer
  • 2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol
CAS-nummer
PubChem CID
DrugBank
CompTox Dashboard (EPA)
ECHA InfoCard100.131.193 Redigér dette på Wikidata
Kemiske og fysiske data
FormelC21H25N3O2S
Molarmasse383,51 g·mol−1
3D-model (JSmol)
  • N\1=C(\c3c(Sc2c/1cccc2)cccc3)N4CCN(CCOCCO)CC4
  • InChI=InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2
  • Key:URKOMYMAXPYINW-UHFFFAOYSA-N

Quetiapin (oprindeligt handelsnavn Seroquel®) er et antipsykotisk lægemiddel til behandling af psykotiske tilstande. Det anvendes til behandling af skizofreni, bipolar affektiv sindslidelse (mani) samt til svær depression. Desuden bruges det i narkotikaafvænning.

Almindelige bivirkninger omfatter vægtøgning, mundtørhed, anæmi (blodmangel), forhøjede kolesterolværdier, hovedpine, søvnighed og svimmelhed.

Årligt sælges der for omkring 1,3 mia. dollars på verdensplan.[1] Quetiapin blev udviklet af AstraZeneca fra 1992–1996 som en videreudvikling og forbedring af den første generation af antipsykofarmaka. Det blev godkendt af det amerikansk Food and Drug Administration i 1997. I dag findes der adskillige generiske versioner af quetiapin.[2]

Kilder og eksterne henvisninger

[redigér | rediger kildetekst]
  1. ^ "www.sec.gov".
  2. ^ "Quepin Full Prescribing Information in Drug Reference Encyclopedia". Hentet 2010-04-03.
Hentet fra "https://da.wikipedia.org/w/index.php?title=Quetiapin&oldid=10514069"
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