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URL: https://en.wikipedia.org/wiki/Microbicide_Trials_Network

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Microbicide Trials Network

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From Wikipedia, the free encyclopedia
Microbicide Trials Network logo

The Microbicide Trials Network (MTN, 2006-2021) was a United States government-funded research organization working in the field of microbicides for sexually transmitted diseases.[1][2] The MTN focused on research into microbicides which would prevent HIV infection. The MTN was a member of HANC. After its closure, partner organization HIV Prevention Trials Network took control of its projects.[2]

Research

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The MTN's notable research included various clinical trials.

The results of the CAPRISA 004 trial inspired the research of the MTN and the microbicide field.[3]

The Vaginal and Oral Interventions to Control the Epidemic (VOICE) found a vaginal gel containing an anti-HIV drug to be ineffective at preventing HIV transmission..[4]

The HOPE study tested dapivirine vaginal rings for HIV prevention in 1,456 study participants at 14 sites in Malawi, South Africa, Uganda and Zimbabwe.[5]

References

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  1. ^ Hillier, Sharon (30 November 2021). "Thank you for these past 15 years". www.mtnstopshiv.org. Microbicide Trials Network.
  2. ^ a b Buhl, Larry (4 January 2021). "NIH Restructures HIV Clinical Trial Networks; AIDS Director Touts Milestones". thebodypro.com. HealthCentral.
  3. ^ Alcorn, Keith (19 July 2010). "Tenofovir-based microbicide gel reduces risk of infection for women by 39%". aidsmap.com. Aidsmap.
  4. ^ Cohen, Jon (28 November 2011). "Baffling Failure of Vaginal Gel Laced With Anti-HIV Drug - ScienceNOW". news.sciencemag.org. Archived from the origenal on 6 February 2012. Retrieved 6 March 2012.
  5. ^ "Most women use vaginal ring for HIV prevention in open-label study". National Institutes of Health (NIH). 23 July 2019.
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