Пређи на садржај

Galaninski receptor 3

С Википедије, слободне енциклопедије
Galaninski receptor 3
Identifikatori
Simboli GALR3;
Vanjski ID OMIM603692 MGI1329003 HomoloGene20798 IUPHAR: GAL3 GeneCards: GALR3 Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 8484 14429
Ensembl ENSG00000128310 ENSMUSG00000047429
UniProt O60755 O88853
RefSeq (mRNA) NM_003614 XM_001001042
RefSeq (protein) NP_003605 XP_001001042
Lokacija (UCSC) Chr 22:
36.55 - 36.55 Mb
Chr 15:
78.87 - 78.87 Mb
PubMed pretraga [1] [2]

Galaninski receptor 3 (GAL3) je G protein spregnuti receptor kodiran GALR3 genom.[1]

Neuropeptid galanin modulira razne fiziološke procese kao što su kognicija/memorija, bol, hormonska sekrecija, način ishrane. Humani galaninski receptori su G protein-spregnuti receptori koji su funkcionalno spregnuti sa njihovim intracelularnim efektorima putem različitih signalnih puteva. GALR3 je nađen u mnogim tkivima i može da bude izražen kao 1.4-, 2.4-, i 5-kb transkripti.[1]

Dodatna literatura

[уреди | уреди извор]
  • Smith KE; Walker MW; Artymyshyn R; et al. (1998). „Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels.”. J. Biol. Chem. 273 (36): 23321—6. PMID 9722565. doi:10.1074/jbc.273.36.23321. 
  • Kolakowski LF; O'Neill GP; Howard AD; et al. (1998). „Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.”. J. Neurochem. 71 (6): 2239—51. PMID 9832121. doi:10.1046/j.1471-4159.1998.71062239.x. 
  • Iismaa TP; Fathi Z; Hort YJ; et al. (1999). „Structural organization and chromosomal localization of three human galanin receptor genes.”. Ann. N. Y. Acad. Sci. 863: 56—63. PMID 9928159. doi:10.1111/j.1749-6632.1998.tb10683.x. 
  • Lapsys NM; Furler SM; Henderson NK; et al. (1999). „A polymorphism in the human GALR3 galanin receptor gene (GALNR3).”. Mol. Cell. Probes. 13 (4): 325—7. PMID 10441207. doi:10.1006/mcpr.1999.0254. 
  • Dunham I; Shimizu N; Roe BA; et al. (1999). „The DNA sequence of human chromosome 22.”. Nature. 402 (6761): 489—95. PMID 10591208. doi:10.1038/990031. 
  • Berger A; Tuechler C; Almer D; et al. (2002). „Elevated expression of galanin receptors in childhood neuroblastic tumors.”. Neuroendocrinology. 75 (2): 130—8. PMID 11867941. doi:10.1159/000048229. 
  • Belfer I; Hipp H; Bollettino A; et al. (2007). „Alcoholism is associated with GALR3 but not two other galanin receptor genes.”. Genes, Brain and Behavior. 6 (5): 473—81. PMID 17083333. doi:10.1111/j.1601-183X.2006.00275.x. 
  • Runesson J; Sollenberg UE; Jurkowski W; et al. (2010). „Determining receptor–ligand interaction of human galanin receptor type 3”. Neurochem. Int. 57: 804—811. PMID 20817064. doi:10.1016/j.neuint.2010.08.018. 

Spoljašnje veze

[уреди | уреди извор]
pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy