Abstract
Diabetic retinopathy (DR) is a leading cause of preventable blindness caused by damaged blood vessels in the eye, if not treated early on. The aim of this research work was to develop a method for the automatic detection of Diabetic Retinopathy and proposing a model for deciding the progression/severity using fundus images. The method was developed so that DR can be detected in an effective and efficient manner before causing damage to the eye, without the presence of an ophthalmologist. The manual screening requires the presence of an ophthalmologist and the resource of time. Detecting exudates is important for the diagnosis of DR. The approach adopted was two-fold: i. extracting features of interest from the images i.e. the blood vessels, optic disc (OD), exudates and microaneurysms by using morphological operations and ii. classifying its progression/severity as either mild or moderate by using the support vector machine (SVM) classifier for helping Ophthalmologists. The performance of the proposed method has been assessed by an ophthalmologist and approved. This paper contributes towards the field of automatic detection of anomalous structures and their severity.
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References
Akram UM, Khan SA (2012) Automated detection of dark and bright lesions in retinal images for early detection of diabetic retinopathy. J Med Syst 36(5):3151–3162
Alassaf N, Gutub A, Parah SA, Al Ghamdi M (2018) Enhancing speed of SIMON: a light-weight-cryptographic algorithm for IoT applications. Multimed Tools Appl 2018:1–25
Aquino A, Gegúndez-Arias ME, Marín D (2010) Detecting the optic disc boundary in digital fundus images using morphological, edge detection, and feature extraction techniques. IEEE Trans Med Imaging 29(11):1860–1869
Centers for Disease Control and Prevention, US Department of Health and Human Services (2011) National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States. Available from Accessed. 2012 Jul;3
Dehghani A, Moghaddam HA, Moin MS (2012) Optic disc localization in retinal images using histogram matching. EURASIP J Image Video Process 2012(1):19
DIARETDB1 (2016) Standard diabetic retinopathy database calibration level , Available at: “www2.it.lut.fi/project/imageret/diaretdb1/.” Accessed: 03- May- 2016.
Doshi D, Shenoy A, Sidhpura D, Gharpure P (2016) Diabetic retinopathy detection using deep convolutional neural networks. In 2016 International Conference on Computing, Analytics and Security Trends (CAST) 2016 Dec 19 (pp. 261-266). IEEE.
El Abbadi NK, Al-Saadi EH (2013) Automatic detection of exudates in retinal images. International Journal of Computer Science Issues (IJCSI) 10(2):237–242
Fleming AD, Philip S, Goatman KA, Williams GJ, Olson JA, Sharp PF (2007) Automated detection of exudates for diabetic retinopathy screening. Phys Med Biol 52(24):7385
Gandhi M, Dhanasekaran R. (2013) Diagnosis of diabetic retinopathy using morphological process and SVM classifier. In Communications and Signal Processing (ICCSP), International Conference on 2013 Apr 3 (pp. 873-877). IEEE
Gargeya R, Leng T (2017) Automated identification of diabetic retinopathy using deep learning. Ophthalmology. 124(7):962–969
Gulshan V, Peng L, Coram M, Stumpe MC, Wu D, Narayanaswamy A, Venugopalan S, Widner K, Madams T, Cuadros J, Kim R, Raman R, Nelson PC, Mega JL, Webster DR (2016) Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. JAMA. 316(22):2402–2410
Gutub A, Al-Ghamdi M (2019) Image based steganography to facilitate improving counting-based secret sharing. 3D Res 10(1):6
Gutub A, Al-Juaid N (2018) Multi-bits stego-system for hiding text in multimedia images based on user security priority. Journal of Computer Hardware Engineering (JCHE) 1(2):1–9
Jose J, Kuruvilla J (2014) Detection of red lesions and hard exudates in color fundus images. Int J Eng Comput Sci 3(10):8583–8588
Kande GB, Savithri TS, Subbaiah PV (2010) Automatic detection of microaneurysms and hemorrhages in digital fundus images. J Digit Imaging 23(4):430–437
Kumari VV, SuriyaNarayanan N (2010) Diabetic retinopathy-early detection using Im-age processing techniques. Int J Comput Sci Eng 2(02):357–361
Li H, Chutatape O (2003, October) model-based approach for automated feature extraction in fundus images. In null (p. 394). IEEE
Nayak J, Bhat PS, Acharya R, Lim CM, Kagathi M (2008) Automated identification of diabetic retinopathy stages using digital fundus images. J Med Syst 32(2):107–115
Oktoeberza KW, Nugroho HA, Adji TB (2015) Optic disc segmentation based on red channel retinal fundus images. In: International Conference on Soft Computing, Intelligence Systems, and Information Technology 2015 Mar 11. Springer, Berlin, Heidelberg, pp 348–359
Priya R, Aruna P (2012) SVM and neural network based diagnosis of diabetic retinopathy. Int J Comput Appl 41(1)
Sanchez, C.I., Mayo, A., Garcia, M., Lopez, M.I. and Hornero, R., 2006. Automatic image processing algorithm to detect hard exudates based on mixture models. In 2006 International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 4453-4456). IEEE
Sinthanayothin C, Boyce JF, Williamson TH, Cook HL, Mensah E, Lal S, Usher D (2002) Automated detection of diabetic retinopathy on digital fundus images. Diabet Med 19(2):105–112
Siva Sundhara Raja D, Vasuki S (2015) Automatic detection of blood vessels in retinal images for diabetic retinopathy diagnosis. Computational and Mathematical Methods in Medicine, 2015.
Sopharak A, Nwe KT, Moe YA, Dailey MN, Uyyanonvara B (2008) Automatic exudate detection with a naive Bayes classifier. In International Conference on Embedded Systems and Intelligent Technology (pp. 139-142)
Ting DS, Cheung CY, Lim G, Tan GS, Quang ND, Gan A, Hamzah H, Garcia-Franco R, San Yeo IY, Lee SY, Wong EY (2017) Development and validation of a deep learning system for diabetic retinopathy and related eye diseases using retinal images from multiethnic populations with diabetes. JAMA 318(22):2211–2223
Tripathi S, Singh KK, Singh BK, Mehrotra A (2013) Automatic detection of exudates in retinal fundus images using differential morphological profile. Int J Eng Technol 5(3):2024–2029
Walter T, Klein JC, Massin P, Erginay A (2002) A contribution of image processing to the diagnosis of diabetic retinopathy-detection of exudates in color fundus images of the human retina. IEEE Trans Med Imaging 21(10):1236–1243
Yanoff M, Cameron D (2012) Diseases of the visual system. In Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders.
Zhu Y, Huang C (2012) An adaptive histogram equalization algorithm on the image gray level mapping. Phys Procedia 25:601–608
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Saman, G., Gohar, N., Noor, S. et al. Automatic detection and severity classification of diabetic retinopathy. Multimed Tools Appl 79, 31803–31817 (2020). https://doi.org/10.1007/s11042-020-09118-8
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DOI: https://doi.org/10.1007/s11042-020-09118-8