Hi
when i was use webhook method with nginx reverse proxy ability with self-signed cert according to this article (https://github.com/python-telegram-bot/python-telegram-bot/wiki/Webhooks), i have this error :

$ tail -f /var/log/nginx/error.log
when run bot python script :
*1 SSL_do_handshake() failed (SSL: error:1408F10B:SSL routines:ssl3_get_record:wrong version number) while SSL handshaking to u, client: YYY.YYY.YYY.YYY, server: 192.168.100.250, request: "POST /XXXXXXX:XXXXXXX-XXY HTTP/1.1", upstream: "https://127.0.0.1:5661/23:XXXXXXX:XXXXXXX-XXY", host: "XXX.XXX.XXX.XXX"

when not run python script :
2018/01/26 11:03:57 [error] 18426#18426: *3287 connect() failed (111: Connection ref) while connecting to upstream, client: YYY.YYY.YYY.YYY, server: 192.168.100.250 request: "POST /XXXXXXX:XXXXXXX-XXY HTTP/1.1", upstream:https://127.0.0.1:5661/XXXXXXX:XXXXXXX-XXY", host: "XXX.XXX.XXX.XXX"

this is my nginx configuration :

server { listen 8443 ssl; server_name 192.168.100.250; ssl_certificate /home/aaa/TelBot/cert.pem; ssl_certificate_key /home/aaa/TelBot/private.key; location /XXXXXXX:XXXXXXX-XXY { proxy_pass https://127.0.0.1:5661; } }

and i run my app with :
updater.start_webhook(listen='127.0.0.1', port=5661, url_path='/XXXXXXX:XXXXXXX-XXY')

when i use nginx as my reverse proxy server this error happened and when i do not use it and directly run script everything is fine !

root@sp2lnx1:/# lsb_release -a
No LSB modules are available.
Distributor ID: Debian
Description: Debian GNU/Linux 9.3 (stretch)
Release: 9.3
Codename: stretch

python 3.6.4
$ nginx -v : nginx version: nginx/1.10.3
$ uname -a : Linux sp2lnx1 4.9.0-5-amd64 #1 SMP Debian 4.9.65-3+deb9u2 (2018-01-04) x86_64 GNU/Linux

$ python3 -m telegram
python-telegram-bot 9.0.0
certifi 2018.01.18
future 0.16.0
Python 3.5.3 (default, Jan 19 2017, 14:11:04) [GCC 6.3.0 20170118]