Fig. 1

Results from substitution tests with the dopamine D4 agonist ABT 724 and 5-HT1A antagonist/D4 agonist WAY 100635 performed in rats trained to discriminate DOI (a, upper panel), LSD-30 (b, middle panel), and LSD-90 (c, bottom panel) rats. All drugs were injected 30 min before tests. %SDL is the percentage of rats that selected the drug-appropriate level. N = 6–14 rats per data point. Right Y-axis and open symbols show the percentage of rats disrupted. Data from LSD-trained rats were presented in Marona-Lewicka and Nichols (2007)