Liporace began his career as an actor in 1963, when he was cast in La terraza, directed by period piece filmmaker Leopoldo Torre Nilsson.

Enrique Liporace was an Argentine actor.

The actor also found success in the theatre, when in 2009 he was cast in Hernán Casciari's play, Más respeto que soy tu madre (More Respect - I'm Your Mother). The play, a slice-of-life tale set during the 1998-2002 Argentine great depression of 2002, cast Liporace opposite famed female impersonator Antonio Gasalla as the Bertottis, and drew a combined audience of half a million in its first 540 shows in Buenos Aires.

He earned extensive credits as a supporting actor in Argentine cinema, television and theatre in subsequent years, working with leading local directors such as Luis Saslavsky, Hugo del Carril, Lucas Demare and Manuel Antín.

Liporace shared an ill-fated relationship with actress Soledad Silveyra during the late 1960s, though the couple never married.