- She was awarded two stars on the Hollywood Walk of Fame: for Radio at 1760 Vine Street, and for Television at 7011 Hollywood Boulevard in Hollywood, California.
- Lurene began her career in radio, providing voices for many characters in the "Sam Spade" series. She portrayed Marjerie Forrester on NBC Radio's "The Great Gildersleeve" during the early 1940s.
- A regular on Red Skelton broadcasts, Lurene was given eight fur coats from Red, one for every year she was on his radio show.
- She taught radio at the University of Southern California and had a private coaching practice for several decades.
- Mother-in-law of John Williams
- First female president of the Hollywood local chapter of AFTRA and was voted "Woman of the Year" by both AFTRA and the Pasadena Playhouse.
- She provided voices on The Red Skelton Hour (1951), notably that of the mother of "Junior", "The Mean Little Kid".
- As president of AFTRA, she once pounded her gavel so hard that it broke. The organization framed it for her.
- She was a staunch conservative Republican. She campaigned for Dwight D. Eisenhower for the 1952 presidential election.
- She was awarded Radio Life magazine's Distinguished Achievement Award for Best Supporting Feminine Player (1944).
- As a teenager, she was one of the original members of Gilmor Brown's acting company, which evolved into the Pasadena Playhouse.
- Once played the president of Lucy Ricardo's women's club on the television series I Love Lucy (1951) (episode "The Club Election" (1953)).
- She was awarded the Diamond Circle Award from the Pacific Pioneer Broadcasters for her extensive radio work.
- She served on the board of the Screen Actors Guild from 1951 through 1954.
- Following her death, she was interred at Forest Lawn Memorial Park in Glendale, California, in the Whispering Pines section.
- Mother of Barbara Ruick.
- Played the role of Effie on the "Sam Spade" radio drama.
- Lurene Tuttle passed away on May 28, 1986, three months before what would have been her 79th birthday on August 29.
- Grandmother of Joseph Williams and Mark Towner Williams.
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