Roth is an actress, musician and trained chef raised in Northern Westchester, New York. She is the daughter of Arlen Roth (born October 30, 1952 in New York, USA), an American guitarist, recording artist, performer, tutor and author. He has performed and recorded with artists such as Bob Dylan, Danny Gatton, John Entwistle, John Prine, James Taylor, Simon and Garfunkel, Ry Cooder, David Lindley, Sonny Landreth, Levon Helm, Bill Kirchen, Duane Eddy, Steve Morse, Albert Lee and Phoebe Snow.

Her song "Call You My Hon" was featured in the award winning feature film "Maria My Love" produced and directed by Jasmine McGlade Chazelle starring Karen Black. Lexie sings "Vaya Con Dios" on the Les Paul Tribute Album "Thank You Les" along side of Keith Richards, Jose Feliciano, Steve Miller, Slash, Billy Gibbons (ZZ Top), Eddie Brigati Jr. (The Young Rascals) and many other greats who played with Les Paul through the years.

Roth lost both her mother, Deborah, and older sister, Gillian MacKenzie Roth (b. 1983) in an auto accident in 1998. Gillian was a gifted actress and guitarist who had just signed to have her own Nickelodeon Show, "The Gunks", an all-girl band loosely based on "The Monkees". She recorded the theme for the show just 2 days before the accident.

Roth is slated to release a new EP of all original music on March 31st 2017, followed by a supporting tour.