Patrick Musisi Nkakalukanyi was born to Sebina Musoke Micheal an accountant and Christine Nansubuga Nabawanuka - a business woman. The last of 10 siblings grew up in a small town called Mawokota in today's Mpigi and went to old Kampala primary school for his elementary school, then moved to Seeta boarding school for his primary education. After that he did secondary school at Uganda martyrs secondary school Namugongo. In 2009, he sat for his advanced level exams. In the same year while in his vacation, the producer of "tricksters", Mrs. Jackie Senyondo gave role and that he continued with "tricksters" even at the university. In 2011, he auditioned and secured a role in a play entitled "silent voices" by Judith Adong, a play about the war in northern Uganda and the ensuing amnesty program and played 'Omony' a son to a murderous woman traumatized by her past. Soon after he landed a role in Moses Ray's "The Counsellor" where he played a young husband desperate to save his marriage. In 2013 he was the face of the "Sadolin color your world commercial". He has also featured in a short film "rhythms of life" where he portrays a pastor with ulterior motives.