Ron Howard stated in interviews that when he was starring on The Andy Griffith Show (1960) and Happy Days (1974), he felt the impact that he was in a hit series. With this series, he didn't feel it at all.

Determined not to work for nearly a year, Henry Fonda would film his scenes of the episodes first and the other actors would later film their scenes around it, completing the episodes after Fonda was finished.

Mike Minor sings the theme song, Primrose Lane. He is the son of executive producer Don Fedderson. Mike also costarred in the later seasons of Petticoat Junction and eventually married Linda Kaye Hennning,

Erin Moran made guest appearances on two episodes, years later, she would star with Ron Howard on Happy Days (1974).

Ron Howard's real-life father, Rance Howard made guest appearances on two episodes of the series. Whereas, his real-life brother, Clint Howard never made any.