Acanthamoeba castellanii: ACA1_360410 Help Entry ACA1_360410       CDS       T02667                                  Name (RefSeq) phosphoinositide 3kinase family, accessory domain (pik domain) domain containing protein   KO K00922   phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] Organism acan  Acanthamoeba castellanii Pathway acan00562   Inositol phosphate metabolism acan01100   Metabolic pathways acan04070   Phosphatidylinositol signaling system acan04081   Hormone signaling acan04620   Toll-like receptor signaling pathway acan05100   Bacterial invasion of epithelial cells Brite KEGG Orthology (KO) [BR:acan00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     ACA1_360410  09130 Environmental Information Processing   09132 Signal transduction    04070 Phosphatidylinositol signaling system     ACA1_360410   09133 Signaling molecules and interaction    04081 Hormone signaling     ACA1_360410  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     ACA1_360410  09160 Human Diseases   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     ACA1_360410  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:acan04131]     ACA1_360410 Enzymes [BR:acan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase      ACA1_360410 Membrane trafficking [BR:acan04131]  Endocytosis   Rab GTPases and associated proteins    Rab associated proteins     ACA1_360410 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd HEAT_2 DUF4135 Peptidase_C14 Motif Other DBs NCBI-GeneID:  14923995 NCBI-ProteinID:  XP_004352502 UniProt:  L8HCV8 LinkDB All DBs Position Unknown AA seq 1368 aa AA seqDB search MSLSVDPMVPAAMRPGEDVFTANLASAITAKSQLKSSGSPSKDPLSSSGGADAVRRPSNA LPSRFGISLVVPSGSQVDLKCGVGDTAADFIRSNFNKMKFMLGATANAAHYVLQTPDGET LASDALVASSAYVEQCVLGKSQPSLFLKPRERGPAPLPPMRPYAMTTSSAPASPSSLSTS PRRLPFSYIPTATPPPSVAALSMASPSSSLELSPPSSPSSSLSSTPRTSNAHSPFSLSPA TSFVAHTQSGDEIPTSPLATTSGRATSSDLSSSPPVIDIDVHEDEPFDLQVLLAGAVTTI VECKPTDTAGNVLTRLDIPDSRLHCYSLATPASNALDGALVLSKLEYIRECRRHYILPQL RVVEDTPSLSKEEKKENKDIGGLIGQKLCWTNVEDEISAFRKTMARVRKEVVLAEELRGL DDGELNIRLSGAPNPTVDRLLIRVVLPLEKKSTNLLVTNDRGMETADSFLQRLLQLPLFS TSGFYHAQTHPHLLLRAKGRLEHIVGKYPLLAFGMECVESKRWPKLVLLKRSEDYIALAK PKQDDASASSSSTTTAGWTSARVPRTPRVRATPFSPRLGGASEGTRDVGESETGPTAIQE VKAGEATEWEENCEGDQVDDEEEALAPRYDHALMAGELVRWDQKSHISLWELENRPFRIK VMGVERTNELGCPSWRKFSPDLAPDDVIGSLYVHVGVYYGGQLLVKDAVTKPVPCSANPR WGQWLTFDDLLFSNESRVCCTLYAKTARDTDAIPLAWANFNIFDYKHELRSGLHTLSMWP DGPANPIGTCVGNAGFAHATQLALELDSFPLPVVFPTDGTTGKTKGPNRNSCLVLGGGEE ELELVEEVEKILAMDSLHRLTPTQKKIVNTLRGYCLARPNALPKFLQAVNYADHISVQEM HSLLGFFRQPTAVEALELLDSKFPDAKVRDHAVECLEALSHDELLDYLLQLVQVIKYEAY HDSGNAFYWYLRSEVHAPEISERYSLILEAYLRGSPSHRRRLHRQNQALNAIYHVGTKIK GLNSIQHSSRLSQDEAIKTEEERAEVLSAALAVIKLPSTFGLPLRADMEVADLLTDKCKF MDSKKRPLWLVFENAQPARPPIYTIFKCGDDLRQDMLTLQMLRIMDKMWKNEGYDLCVTP YGCIATGADMGFIENSATTAAVAKESGYGARGAFKEDPLKNWLLKHNPTKEQWDAALRNF IRSCAAYCVATYVLGIGDRHNDNVMVTKDGRLFHIDFGHFLGNFKKKFGFKRERAPFVLT PDHAFVMGGRGSEGFTLFITTACRAYNILRKHAMGTSLLNLTVFLLEQTGIPELKSAEDL EYLRYAFATDLDDNAAAARFTELIHAALDCWTTRFNNAIHLIAHGGKG NT seq 4107 nt NT seq  +upstreamnt  +downstreamnt atgtcgctgtcggtcgaccccatggtgccggcggcgatgcggccgggcgaagacgtgttc acggccaacctggcgtcggcgatcacggccaagagccagctcaagtcctccgggtcccct tccaaagacccgctctcgtcctccggaggcgccgatgccgtgcgccggccttccaacgct ctcccctcgcgctttggcatctccctcgtcgtcccgtcaggctcgcaggtggatctgaaa tgtggtgtgggcgacacagcagccgacttcatccgctccaactttaacaagatgaagttt atgctgggcgcgacagcgaatgcagcccactatgtgctgcaaacgcccgacggagagaca ctcgcctcggatgcgctggtcgcgagcagtgcctacgtggagcagtgcgtgctgggcaaa tcgcagccctcactcttcctcaagccccgagagcgcggccctgctccgctgccgcccatg cggccgtatgccatgaccacctcgtcggcgcccgcctctccctcttccctctccacctcc ccgcggcgactgcccttcagctacatacccaccgcgacaccgccgccgagcgtggcggcc ctatccatggccagtccgtcgtcgtcgctcgaattgtcgccgccctcatcgccctcgtca tcgctgtcctcgacaccgcgcacgtccaacgcccactcgcccttttccctctcgccggcc acctccttcgtggcgcacactcagtcgggcgatgagatcccgacctcgcccctcgccacc acgtccgggcgtgctacgtcatccgatctctcttcgtcgccgccggtcatcgacatcgat gtccacgaggacgagccgtttgacctgcaggtgctgctggcgggggcggtgacaacgatc gtggaatgcaagccgaccgacactgcaggcaacgtgctcacgcgtctggacattcccgac tcccgcctgcattgctacagtctggccactcctgcctcaaacgccctcgatggcgctctc gtgctgtccaagctcgagtacattcgcgagtgcagaaggcactacatcctcccccagcta cgggtggtcgaggacacaccgagcctgagcaaagaggaaaagaaagaaaacaaagacatt ggcggattgatcgggcagaagctgtgttggaccaatgtagaggatgagatttcagcgttc cgcaagaccatggccagagtgaggaaagaagtggtgctggccgaagaactgcgaggattg gacgacggggagctcaacatccgattgtccggcgcgcccaatcccactgtcgatcgcctg ctcatccgggtcgtgctgccgctcgagaagaagagcaccaacctgctcgtcaccaacgat aggggaatggagactgcggattccttcctgcagcgactgcttcagctgcccctgttctcg acctccggcttctaccacgcccagacgcacccgcacctcctgctacgagccaagggcagg ctggaacacatcgtgggcaagtacccgttgctggcctttggtatggaatgcgtggaaagt aagcgttggccgaagctggtgctgctcaagcgatcggaggactacatcgcgctggccaaa cccaaacaagacgacgcttccgcatcatcgtcgtcaaccaccactgccgggtggacctcc gcccgcgtcccgcgcaccccacgagtgcgtgcgacaccattttcgccgcgcttgggagga gccagcgaggggacgagagacgtcggcgagtcggagacagggccgacagcgatacaagag gtgaaggcgggcgaagcgacggagtgggaggagaattgcgagggagaccaggtcgacgat gaagaggaggccctcgcgccgcgctatgaccacgctctcatggccggcgagctggtgagg tgggaccaaaagtcgcacatctccctgtgggagctggagaaccggccatttcgaatcaaa gtgatgggcgtggagaggaccaacgaattgggctgtccctcgtggaggaagttctccccc gatctcgctccggacgacgtcatcggctctctttacgtccacgtcggggtgtactacgga ggacagctgctggtgaaggacgcggtcacaaagcccgtgccgtgttctgccaacccgcgc tgggggcagtggctcacgttcgacgatctactcttctcgaatgaatcgcgcgtttgctgc accctctatgcgaaaacggccagagacacggacgcaattccgcttgcttgggccaacttc aacatcttcgactacaagcacgaactacggtccggcttgcacaccctctccatgtggccg gacggaccggccaacccgatcggcacatgcgtgggtaatgcgggctttgcgcacgccacg cagctcgcactcgagctcgactcctttcccctccccgtcgtctttcccaccgatggcacg acgggcaagacgaagggacccaaccgcaattcttgcctggtgctgggcggcggagaggaa gaactggagctggtggaagaggtggagaagatactcgccatggactctcttcaccggctg accccgacccaaaagaagatcgtcaacacgctgcgcggctactgtctggcgcggcccaac gccttgccgaagtttttgcaggccgtcaactatgccgaccacatatctgtccaggagatg cactcgttgctgggcttcttcagacagccaacggcagtcgaggccctggagcttctcgac tccaagttccccgatgctaaggtgcgagatcatgcggtcgaatgtctggaggccttgtcc cacgatgagctgctcgactacctcctccagttggtgcaggtcatcaagtatgaagcctat catgactctggcaatgcgttctattggtacctgcgatcggaggtgcacgcgccggagatc tcggagcggtacagcctcatcctcgaggcctacctccgcggctcgccgtcccaccgtcgt cggctgcatcgacagaaccaagccctcaacgccatctaccacgtcggaactaaaatcaag ggcttgaactccattcaacattcatctcgtctgtcccaggacgaagcgatcaagacggaa gaggagcgggccgaggtgctgagcgccgcactggcggtgatcaagctgccctccaccttt gggctgccgctgcgggcggacatggaggtggcagatctcctcacagacaagtgcaagttc atggactccaagaagcggccgctgtggctcgtctttgagaacgcccaacccgcgcgaccg cccatctacaccattttcaagtgtggcgacgatctccgtcaggacatgttgacgctgcag atgcttcgaatcatggacaagatgtggaaaaacgagggctacgatctgtgtgtgacgccc tatggctgcattgccaccggggcggacatgggtttcattgagaactcggcaaccacggct gcagtcgccaaggagtcgggctacggggccagaggcgccttcaaggaggacccgctcaag aactggctgctcaagcacaaccccaccaaagaacagtgggacgcggcgctgagaaacttc atccgatcttgtgcggcgtactgcgtggccacctatgtgctggggattggcgatcgacac aacgacaacgtgatggtgaccaaggacggccgactgttccacatcgacttcggccatttc ctggggaacttcaaaaagaaattcggcttcaagcgggaacgcgctccgttcgtgctgacc ccggaccacgccttcgtgatgggcggtcgcggcagcgaaggattcacactcttcattaca actgcttgccgcgcctacaacatccttcgcaagcacgccatgggaacgagcctgctaaac ttgaccgtattcctcctcgagcagacgggcattccagagctgaagagcgcagaggacctg gagtacctgcgctacgccttcgcaaccgatcttgacgacaatgcagccgcagcccgcttt accgagctcatacacgccgccctcgactgctggaccacacgcttcaacaacgccatccac ctcatcgcgcacggcggcaagggctga

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