Leopardus geoffroyi (Geoffroy's cat): 123611503 Help Entry 123611503         CDS       T10761                                  Symbol PIK3CB Name (RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform   KO K00922   phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] Organism lgf  Leopardus geoffroyi (Geoffroy's cat) Pathway lgf00562   Inositol phosphate metabolism lgf01100   Metabolic pathways lgf01521   EGFR tyrosine kinase inhibitor resistance lgf01522   Endocrine resistance lgf01524   Platinum drug resistance lgf04012   ErbB signaling pathway lgf04014   Ras signaling pathway lgf04015   Rap1 signaling pathway lgf04024   cAMP signaling pathway lgf04062   Chemokine signaling pathway lgf04066   HIF-1 signaling pathway lgf04068   FoxO signaling pathway lgf04070   Phosphatidylinositol signaling system lgf04071   Sphingolipid signaling pathway lgf04072   Phospholipase D signaling pathway lgf04081   Hormone signaling lgf04140   Autophagy - animal lgf04150   mTOR signaling pathway lgf04151   PI3K-Akt signaling pathway lgf04152   AMPK signaling pathway lgf04210   Apoptosis lgf04211   Longevity regulating pathway lgf04213   Longevity regulating pathway - multiple species lgf04218   Cellular senescence lgf04360   Axon guidance lgf04370   VEGF signaling pathway lgf04380   Osteoclast differentiation lgf04510   Focal adhesion lgf04550   Signaling pathways regulating pluripotency of stem cells lgf04611   Platelet activation lgf04613   Neutrophil extracellular trap formation lgf04620   Toll-like receptor signaling pathway lgf04625   C-type lectin receptor signaling pathway lgf04630   JAK-STAT signaling pathway lgf04650   Natural killer cell mediated cytotoxicity lgf04660   T cell receptor signaling pathway lgf04662   B cell receptor signaling pathway lgf04664   Fc epsilon RI signaling pathway lgf04666   Fc gamma R-mediated phagocytosis lgf04668   TNF signaling pathway lgf04670   Leukocyte transendothelial migration lgf04722   Neurotrophin signaling pathway lgf04725   Cholinergic synapse lgf04750   Inflammatory mediator regulation of TRP channels lgf04810   Regulation of actin cytoskeleton lgf04910   Insulin signaling pathway lgf04914   Progesterone-mediated oocyte maturation lgf04915   Estrogen signaling pathway lgf04917   Prolactin signaling pathway lgf04919   Thyroid hormone signaling pathway lgf04923   Regulation of lipolysis in adipocytes lgf04926   Relaxin signaling pathway lgf04929   GnRH secretion lgf04930   Type II diabetes mellitus lgf04931   Insulin resistance lgf04932   Non-alcoholic fatty liver disease lgf04933   AGE-RAGE signaling pathway in diabetic complications lgf04935   Growth hormone synthesis, secretion and action lgf04960   Aldosterone-regulated sodium reabsorption lgf04973   Carbohydrate digestion and absorption lgf05010   Alzheimer disease lgf05017   Spinocerebellar ataxia lgf05020   Prion disease lgf05100   Bacterial invasion of epithelial cells lgf05132   Salmonella infection lgf05135   Yersinia infection lgf05142   Chagas disease lgf05146   Amoebiasis lgf05160   Hepatitis C lgf05161   Hepatitis B lgf05162   Measles lgf05163   Human cytomegalovirus infection lgf05164   Influenza A lgf05165   Human papillomavirus infection lgf05166   Human T-cell leukemia virus 1 infection lgf05167   Kaposi sarcoma-associated herpesvirus infection lgf05168   Herpes simplex virus 1 infection lgf05169   Epstein-Barr virus infection lgf05170   Human immunodeficiency virus 1 infection lgf05171   Coronavirus disease - COVID-19 lgf05200   Pathways in cancer lgf05203   Viral carcinogenesis lgf05205   Proteoglycans in cancer lgf05206   MicroRNAs in cancer lgf05207   Chemical carcinogenesis - receptor activation lgf05208   Chemical carcinogenesis - reactive oxygen species lgf05210   Colorectal cancer lgf05211   Renal cell carcinoma lgf05212   Pancreatic cancer lgf05213   Endometrial cancer lgf05214   Glioma lgf05215   Prostate cancer lgf05218   Melanoma lgf05220   Chronic myeloid leukemia lgf05221   Acute myeloid leukemia lgf05222   Small cell lung cancer lgf05223   Non-small cell lung cancer lgf05224   Breast cancer lgf05225   Hepatocellular carcinoma lgf05226   Gastric cancer lgf05230   Central carbon metabolism in cancer lgf05231   Choline metabolism in cancer lgf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer lgf05415   Diabetic cardiomyopathy lgf05417   Lipid and atherosclerosis lgf05418   Fluid shear stress and atherosclerosis Brite Enzymes [BR:lgf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase      123611503 (PIK3CB) Membrane trafficking [BR:lgf04131]  Endocytosis   Rab GTPases and associated proteins    Rab associated proteins     123611503 (PIK3CB) BRITE hierarchy Other DBs NCBI-GeneID:  123611503 NCBI-ProteinID:  XP_045359445 LinkDB All DBs Position C2 AA seq 1070 aa AA seqDB search MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS NT seq 3213 nt NT seq  +upstreamnt  +downstreamnt atgtgcttcaatttcataatgcctcctgctatggcagacatccttgacatctgggcagtg gattcacagttagcatctgatggctccatacctgtggatttccttttgcccactgggatt tatattcagttggaggttcctcgcgaggctaccatttcctatattaaacagatgttatgg aagcaagttcacaattacccaatgtttaacctccttatggaaattgactcctatatgttt gcatgtgtgaatcaaactgctgtatatgaggagcttgaagatgaaacaagaaggctctgt gatgtcagaccttttcttccagttctcaaattagtgacaagaagttgtgacccaggggaa aaattagactcaaaaattggagtccttataggaaaaggtctacatgaatttgatgcactg aaggatcctgaagtgaatgaattccgaataaaaatgcgcaaattcagtgaagaaaagatt cagtcacttgtgggactgtcttggatggattggctaaaacagacgtatccaccagaacat gaaccatccatccttgaaaacttagaagataaactttatggaggaaagctcattgtggct gttcattttgaaaattgtcaggatgtgtttagctttcaaatatctcctaatatgaatcct atcaaaataaatgaactggcaatccaaaaacgtttgactattcatgggaaagaagatgaa gttagcccgtatgactatgtgttacaagtcagtgggcgagtagaatatgtgtttggtgat cacccactaattcagttccagtatatccggaactgtgtaatgaataggaccttgcctcat tttatgcttgtggaatgttgcaagatcaagaagatgtatgaacaggaaatgattgccata gaagctgccataaatagaaattcatcaaaccttcctcttcctttaccaccaaagaaaatg cgaattatttctcatgtttgggaaaataacaaccctttccaaattgtcttggttaaggga aataaacttaacacagaagaaagtgtaaaagttcatgtcagggctggcctttttcatggt accgaactcctgtgtaaaaccatcgtaagctcagagatatcagggaaaaatgatcacatt tggaatgaaccactggaatttgatataaatatttgtgacctgccacgaatggctcgatta tgttttgctatttatgcagttttggataaagtgaaaacgaaaaaatcgactaaaactatt aatccctctaaatatcagaccatccggaaatctgggaaagtgcattatcctgtagcatgg gtaaatacaatggtttttgactttaaaggacagttgagatctggagacataatattgcac agctggtcttcatttcctgatgaacttgaagaaatgttgaatccaatgggaactgttcag acaaatccatatacggaaaatgcaacagctttgcatatcaaattcccagagaataaaaaa caaccttattattatcctccctttgataagataatcgagaaggcagctgagattgcaagc agtgacagtgctaatgtatcaagtcgaggtggaaaaaagtttcttgctgtactgaaagaa atcttggacagggatcccttgtctcaactgtgtgagaacgaaatggatcttatttggact ttgcgacaagattgcagagagaatttcccacagtcactgccaaaattactgctgtcgatc aagtggaataaacttgaagatgttgctcagcttcaagccctacttcagatttggcctaaa ctgcccccccgggaggccttggagcttctagatttcaactatccagatcagtacgtgcga gaatatgctgtgggctgcctgcgacagatgagtgatgaagaactctctcaatatctttta caactggtgcaagttttgaaatacgagccttttcttgattgtgccctctctagattccta ttagaaagagcacttgctaaccgcaggatagggcagtttctattttggcaccttaggtca gaagtgcatattcctgctgtctcagtacagtttggtgtcatccttgaagcatactgccgg ggaagtgtagggcatatgaaagtgctttctaagcaggttgaagcactcaataagttaaaa actttaaatagtttaatcaaactgaatgcaatgaagctaaacagagccaaagggaaggag gccatgcatacttgtttaaaacagaatgcttaccgggaagccctctctgacctgcagtca cctctgaatccgtgtgtcatcctctcagaactctatgttgaaaaatgtaaatacatggat tccaaaatgaagcctttgtggctcgtgtacaacaacaaagtttttggtgaggattcagtt ggagtgatttttaaaaatggtgatgatttacgacaagatatgttgacactccagatgttg cgcttgatggatttactttggaaagaagctggtctggatcttcggatgctgccttatggc tgtttagcaacaggagaccgctctggcctcatcgaagttgtgagcacctctgaaacaatt gctgacattcagctgaacagtagcaatgtggctgcagcagcggccttcaacaaagacgcc cttctgaactggcttaaagaatacaactctggggatgacctagaccgagccattgaagag tttaccttgtcctgtgccggctactgtgtagcttcttatgtccttgggattggtgataga catagtgacaacatcatggtcaagaaaaccggccagctcttccacattgactttggacat attcttggaaatttcaagtctaaatttggcattaaaagggaacgagtgccttttattctt acctatgatttcattcatgtgattcaacaaggaaaaacaggaaacacagaaaaatttggc cgtttccgccagtgttgtgaggatgcatatctgattttacgacgtcacgggaatctcttc atcactctttttgcactgatgttgactgcagggcttcctgagcttacatcagtcaaggat atacagtatcttaaggactctcttgccttaggaaagagtgaagaagaagcgcttaagcaa tttaagcaaaaatttgatgaggcactcagggaaagctggactactaaagtgaactggatg gcccacacagttcggaaagactacagatcttaa

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