CV Jain Isha
CV Jain Isha
Curriculum Vitae
CONTACT INFO
17 Elm St., Apt. 6
Cambridge, MA 02139
Email: ijain@mit.edu
EDUCATION
Harvard-MIT Health Sciences and Technology, PhD, Computer Science 2012- 2017
Harvard University, AB, Chemical and Physical Biology, magna cum laude 2008- 2012
Lehigh University (Pre-college) 2004- 2008
RESEARCH EXPERIENCES
1. Harvard Medical School | Vamsi Mootha Lab | Systems Biology 2013- present
Development of hypoxia as a therapy for mitochondrial disease
Use of computational and systems biology, molecular biology and physiology to
determine mitochondrial disease pathology and therapeutics
Systematic characterization of cellular and organismal oxygen sensing pathways,
adaption to oxygen and role of oxidative stress in disease pathologies
4. Max Planck Institute| Wulf Blankenfeldt Lab | Structural Biology 2008 Spring
Crystallization and biochemical characterization of enzymes involved in phenazine
synthesis pathway
5. Lehigh University| Kathy Iovine Lab | Developmental Biology 2004-2008
Characterization and modeling of bone growth patterns in zebrafish fins
Identification of the role of gap junction proteins in determining bone growth kinetics
PUBLICATIONS
1. M. Ferrari*, I. H. Jain*, Goldberger, OV. K. Mootha**, W.M. Zapol**. Hypoxia
treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.
PNAS, 114 (21), E4241-E4250 (2017). [*equal contribution]
2. I. H. Jain, L. Zazzeron, R. GoliF. Zhang, W. Goessling, W. M. Zapol, V. K. Mootha.
Hypoxia as a therapy for mitochondrial disease. Science, 352 (6281), 54-61 (2016).
3. I. H. Jain*, V. Vijayan*, E.K. OShea. Spatial ordering of chromosomes enhances the
fidelity of chromosome partitioning in cyanobacteria. PNAS, 109 (34), 13638-13643
(2012). [*equal contribution]
4. V. Vijayan, I. H. Jain, E.K. OShea. A high resolution map of a cyanobacterial
transcriptome. Genome Biology, 12:R47 (2011). Highly accessed article.
5. A. D. Hoptak-Solga, S. Nielsen, I. H. Jain, R. Thummel, D. Hyde, and M. K. Iovine.
Connexin43 (GJA1) is required in the population of dividing cells during fin
regeneration. Developmental Biology, (2008)
6. I. H. Jain, C. Stroka, J. Yan, W. Huang, M. K. Iovine. Bone growth in zebrafish fins
occurs via multiple pulses of cell proliferation. Developmental Dynamics, 236, 2668-
2674 (2007)
7. A. Sharma, H. Jain, J. O. Carnali, I. H. Jain. Inhomogeneous evolution of a glass surface
via free, rapid expansion. Applied Physics Letters, 83, 2802-2804 (2003)
8. H. Jain and I. H. Jain. Discovering the Science and Technology of Glass Formation from
Candy Making. Proc. Am. Soc. Eng. Edu., Session 3264, pp 1-7 (2002)
9. H. Jain and I. H. Jain. Learning the Principles of Glass Science and Technology from
Candy Making. Standard Experiments in Engineering Materials, Science and
Technology, NEW: Update 2000. NASA/CP-2001-211029. pp. 169-182 (2001).
MAJOR INTERNATIONAL AND NATIONAL AWARDS
1. Harold Weintraub Graduate Student Award 2017
2. Philanthropic Educational Organization National Scholar Award ($15K) 2016
3. Barry Goldwater Scholarship 2011
4. Glamour Magazines Top 10 College Women 2009
5. Discover Magazines Top Five Scientists Under 20 2008
6. Siemens Math, Science & Technology Competition, National Winner ($100K) 2007-08
7. LOreal Women in Science, Invited Panelist 2008
8. Intel Science Talent Search Finalist 2008
9. Intel Science and Engineering Fair, First Place Award 2007
10. 36th Intl Metallographic Contest First Prize, George Kehl Award 2004
11. First Prize, Natl Educators Workshop, Undergrad Research Poster Contest 2003
OTHER ACTIVITIES/INTERESTS
1. Soccer Intramural House Team 2009-11
2. Middle Eastern Dancing 2008-09; 2011
3. Salsa Dance 2011