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Crush The Hydroxyethylcellulose (If Not Fine Powder) and Slowly Add

This document provides instructions for creating a gel containing ascorbic acid, ferulic acid, and vitamin E. It involves dissolving ferulic acid in water at 60°C, then adding ascorbic acid and alpha tocopherol dissolved in propylene glycol. Hydroxyethylcellulose is added last to form the gel while adjusting the pH to 5.6 using sodium hydroxide solution. The final gel contains 15g ascorbic acid, 0.5g ferulic acid, 1mL alpha tocopherol, and is made up to 100mL total volume with water and other components.

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Jai Murugesh
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75 views2 pages

Crush The Hydroxyethylcellulose (If Not Fine Powder) and Slowly Add

This document provides instructions for creating a gel containing ascorbic acid, ferulic acid, and vitamin E. It involves dissolving ferulic acid in water at 60°C, then adding ascorbic acid and alpha tocopherol dissolved in propylene glycol. Hydroxyethylcellulose is added last to form the gel while adjusting the pH to 5.6 using sodium hydroxide solution. The final gel contains 15g ascorbic acid, 0.5g ferulic acid, 1mL alpha tocopherol, and is made up to 100mL total volume with water and other components.

Uploaded by

Jai Murugesh
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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VITAMIN C GEL, ACID FERULIC AND VITAMIN E

Ascorbic acid 15 g

Ferulic acid 0.5 g

Alpha Tocopherol 1 mL

Propylene glycol 5 mL

Hydroxyethylcellulose (5000 CPS) 2 g

20% NaOH aqueous solution c s

Water Conservans csp 100 mL

MODUS OPERANDI

1 make the necessary calculations.

2. weigh or measure each component properly.

3. dissolve the Ferulic acid in 60 mL of water Conservans at 60 C using a Shaker.

4 cool Ferulic solution add vitamin C and continue stirring until it dissolves.

5 dissolve alpha tocopherol in propylene glycol and add it to the above solution
while stirring.

6. adjust the pH to 5.6 with NaOH solution, which requires to add approximately
10 mL of the solution.

7. crush the Hydroxyethylcellulose (if not fine powder) and slowly add
to the previous solution stirring while cooling to form the gel.

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