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Introduction To Statistics & Probability: Chapter 3: Producing Data (Part 3)

This document provides an overview of statistical inference and ethics in research studies. It discusses key concepts like parameters, statistics, sampling variability, bias, and sampling distribution. It emphasizes the importance of random sampling to reduce bias and larger sample sizes to reduce variability. The document also outlines ethical guidelines for research involving human subjects, including requiring institutional review boards, informed consent, maintaining confidentiality, and considerations for clinical trials and behavioral experiments.

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0% found this document useful (0 votes)
49 views17 pages

Introduction To Statistics & Probability: Chapter 3: Producing Data (Part 3)

This document provides an overview of statistical inference and ethics in research studies. It discusses key concepts like parameters, statistics, sampling variability, bias, and sampling distribution. It emphasizes the importance of random sampling to reduce bias and larger sample sizes to reduce variability. The document also outlines ethical guidelines for research involving human subjects, including requiring institutional review boards, informed consent, maintaining confidentiality, and considerations for clinical trials and behavioral experiments.

Uploaded by

Kenesa
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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1

INTRODUCTION TO
STATISTICS & PROBABILITY

Chapter 3: Producing Data


(Part 3)

Dr. Nahid Sultana


Chapter 3: Producing Data
2

Introduction
3.1 Design of Experiments
3.2 Sampling Design
3.3 Toward Statistical Inference
3.4 Ethics
3.3 Toward Statistical Inference

 Parameters and Statistics


 Sampling Variability
 Sampling Distribution
 Bias and Variability
 Sampling from Large Populations

3
Parameters and Statistics
Using samples to talk about populations
4

A parameter is a number that describes some characteristic of the population.


In statistical practice, the value of a parameter is not known because we cannot
examine the entire population.
Name Symbol Example
Mean µ In a nationwide test, what is the average score?
Proportion p What proportion of people choose chocolate as their favorite ice cream
flavor?
We answer such questions by studying a sample….
A statistic is a number that describes some characteristic of a sample. The
value of a statistic can be computed directly from the sample data.
Name Symbol Example
Sample Mean x Sample mean of 100 test scores
Sample  Sample proportion of 100 people who choose chocolate
Proportion p as their favorite ice cream flavor?
Parameters and Statistics
Examples:
5

 Proportion of all students who attended the last home football game.
Parameter, p
 Proportion of registered voters who voted in November.
Parameter, p
 Mean height of a sample of NBA basketball players.
Statistics, x
 Mean SAT of entering freshmen
Parameter, µ
 Proportion of people who prefer Coke over Pepsi in a sample of mall
shoppers
Statistics,
 Mean number of pepperoni slices on a 12̎ pizza from a sample of a
certain brand of pepperoni pizzas.
Statistics, x
Statistical Estimation
6

 The process of statistical inference involves using information


from a sample to draw conclusions about a wider population.
 Your estimate of the population is only as good as your sampling
design.
 Work hard to eliminate biases.
 Your sample is only an estimate—and if you randomly sampled
again you would probably get a somewhat different result.
 Bigger sample is better.
Sampling Variability
7

 Each time we take a random sample from a population, we are


likely to get a different set of individuals and calculate a different
statistic. This is called sampling variability.
 We ask, “What would happen if we took many samples?”
 Take a large number of samples from the same population.
 Calculate the sample mean/proportion for each sample.
 Make a histogram of these values.
 Examine the distribution displayed in the histogram for shape,
center, and spread, as well as outliers or other deviations.
Sampling Variability (Cont…)
8

 The sampling distribution of a statistic is the distribution of that


statistic for samples of a given size n taken from the same
population.

The variability of a statistic is described by the spread of its


sampling distribution. This spread depends on the sampling design
and the sample size n, with larger sample sizes leading to lower
variability.
9

The results of many SRSs have a regular pattern. Here, we draw 1000 SRSs
of size 100 from the same population. The population proportion is p = 0.60.
The histogram shows the distribution of the 1000 sample proportions.

The distribution of sample proportions for 1000 SRSs of size 2500 drawn
from the same population as in first figure. The two histograms have the same
scale. The statistic from the larger sample is less variable.
Bias and Variability
10

Both bias and variability describe what happens when we take many
shots at the target.
Bias concerns the center of the sampling
distribution. A statistic used to estimate a
parameter is unbiased if the mean of its
sampling distribution is equal to the true
value of the parameter being estimated.

The variability of a statistic is described


by the spread of its sampling distribution.
This spread is determined by the sampling
design and the sample size n. Statistics
from larger probability samples have
10 smaller spreads.
Managing Bias and Variability
11

A good sampling scheme must have both small bias and small variability.

To reduce bias, use random sampling.


To reduce variability of a statistic from an SRS, use a larger sample.

POPULATION SIZE DOESN’T MATTER


The variability of a statistic from a random sample does not depend
on the size of the population, as long as the population is at least
100 times larger than the sample.
3.4 Ethics
12

 Institutional Review Boards


 Informed Consent
 Confidentiality
 Clinical Trials
 Behavioral and Social Science Experiments
Institutional Review Boards
13

 The organization that carries out the study must have an


institutional review board that reviews all planned studies in
advance in order to protect the subjects from possible harm.
 The institutional review board:
 reviews the plan of study
 can require changes
 reviews the consent form
 monitors progress at least once a year
Informed Consent
14

 All subjects must give their informed consent before data are
collected.
 Subjects must be informed in advance about the nature of a study
and any risk of harm it might bring.
 Subjects must then consent in writing.
 Who can’t give informed consent?
 prison inmates
 very young children
 people with mental disorders
Confidentiality
15

 All individual data must be kept confidential. Only statistical


summaries may be made public.
 Confidentiality is not the same as anonymity. Anonymity means
that subjects are anonymous—their names are not known even to
the director of the study. Anonymity prevents follow-ups to
improve non-response or inform subjects of results.
 Any breach of confidentiality is a serious violation of data ethics.
 The best practice is to separate the identity of the subjects from
the rest of the data immediately!
Clinical Trials
16

 Clinical trials study the effectiveness of medical treatments on actual


patients—these treatments can harm as well as heal.
 Points for a discussion:
 Randomized comparative experiments are the only way to
see the true effects of new treatments.
 Most benefits of clinical trials go to future patients. We must
balance future benefits against present risks.
Behavioral and Social Science
17
Experiments
 Many behavioral experiments rely on hiding the true purpose of the
study.
 Subjects would change their behavior if told in advance what
investigators were looking for.
 The “Ethical Principles” of the American Psychological Association
require consent unless a study only observes behavior in a public
space.

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