ANTIBIOTICS CHEAT SHEET :) * Macrolides SE: Motilin stimulation, QT prolongation,

Also, REMEMBER!!!! reversible deafness, eosinophilia, cholestatic hepatitis

* Sulfonamides compete for albumin with: * Bactericidal: beta-lactams (penicillins, cephalosporins,
 Bilirrubin: given in 2°,3°T, high risk or indirect monobactams, carbapenems), aminoglycosides,
hyperBb and kernicterus in premies fluorquinolones, metronidazole.
 Warfarin: increases toxicity: bleeding * Baceriostatic: tetracyclins, streptogramins,
chloramphenicol, lincosamides, oxazolidonones, macrolides,
* Beta-lactamase (penicinillase) Suceptible:
sulfonamides, DHFR inhibitors.
 Natural Penicillins (G, V, F, K) * Pseudomembranous colitis: Ampicillin, Amoxicillin,
 Aminopenicillins (Amoxicillin, Ampicillin) Clindamycin, Lincomycin.
 Antipseudomonal Penicillins (Ticarcillin, Piperacillin) * QT prolongation: macrolides, sometimes
* Beta-lactamase (penicinillase) Resistant: fluoroquinolones
 Oxacillin, Nafcillin, Dicloxacillin Reblogging for the 100th time!!!! (sorry)
I’ve made some corrections and added ABs that didn’t
 3°G, 4°G Cephalosporins
include before!!! Here’s the link if you want to download the
 Carbapenems corrected chart: [Antibiotics doc]
 Monobactams Also, I’m gonna add a couple of things that didn’t mention
 Beta-lactamase inhibitors before:
* Penicillins enhanced with: * MRSA: Ceftaroline, Telavancin, Dalbavancin, Oritavancin,
 Clavulanic acid & Sulbactam (both are suicide Vancomycin, Linezolid, Tidezolid, Daptomycin, Tigecyclin.
inhibitors, they inhibit beta-lactamase) * Skin MRSA: TMP/SMX, Clindamycin, Doxycycline,
Linezolid
 Aminoglycosides (against enterococcus and
* FQ: Gemi, Levo, Ciprofloxacin cover Pseudomona but
psedomonas)
do NOT cover anaerobes. Moxifloxacin covers anaerobes
* Aminoglycosides enhanced with Aztreonam
but do NOT cover Pseudomona.
* Penicillins: renal clearance EXCEPT Oxacillin &
* Ertapenem DOES NOT cover Pseudomona
Nafcillin (bile)
* mAcrolides DO NOT cover stAph.
* Cephalosporines: renal clearance EXCEPT Cefoperazone
* ciPRofloxacin DOES NOT cover stReP
& Cefrtriaxone (bile)
* Cefoxitin, Cefotetan: the only 2°G cephalosporins that
* Both inhibited by Probenecid during tubular secretion.
cover anaerobes. Also deplete prothombin, so there’s
* 2°G Cephalosporines: none cross BBB
increase risk of bleeding.
except Cefuroxime
* VRE: Tigecycline, Linezolid, Quinupristin/Dalfopristin,
* 3°G Cephalosporines: all cross BBB
Daptomycin
except Cefoperazone bc is highly highly lipid soluble, so is
* ESBL: (BLEE en español) carbapenems, beta
protein bound in plasma, therefore it doesn’t cross BBB.
lactam+beta lactamase inhibitors
* Cephalosporines are "LAME“ bc they do not cover this
Dear @md-admissions (I’m mentioning you, since you and I
organisms
share a passion for ID) & Medblr fam: Are there any
 L isteria monocytogenes corrections and/or additions that you would like to mention?
 A typicals (Mycoplasma, Chlamydia) Thanks :)
 M RSA (except Ceftaroline, 5°G) Hello beautiful lady @md-admissions
 E nterococci I’m reblogging this for the anon that asked about AB a
couple of days ago. This is the updated chart, with extra
* Disulfiram-like info! I’ll also be doing a post on AB coverage soon!
effect: Cefotetan & Cefoperazone (mnemonic) Good luck and may the black cloud go away today <3
* Cefoperanzone: all the exceptions!!!
 All 3°G cephalosporins cross the BBB except
Cefoperazone.
 All cephalosporins are renal cleared, except
Cefoperazone.
 Disulfiram-like effect
* Against Pseudomonas:
 3°G Cef taz idime (taz taz taz taz)
 4°G Cefepime, Cefpirome (not available in the
USA)
 Antipseudomonal penicillins
 Aminoglycosides (synergy with beta-lactams)
 Aztreonam (pseudomonal sepsis)
* Covers MRSA: Ceftaroline (rhymes w/ Caroline, Caroline
the 5°G
Ceph), Vancomycin, Daptomycin, Linezolid, Tigecyclin
e.
* Covers VRSA: Linezolid, Dalfopristin/Quinupristin
* Aminoglycosides: decrease release of ACh in synapse
and act as a Neuromuscular blocker, this is why it enhances
effects of muscle relaxants.
* DEMECLOCYCLINE: tetracycline that’s not used as an
AB, it is used as tx of SIADH to cause Nephrogenic Diabetes
Insipidus (inhibits the V2 receptor in collecting ducts)
* Phototoxicity: Q ue S T ion?
 Q uinolones
 Sulfonamides
 T etracyclines
* p450 inhibitors: Cloramphenicol, Macrolides (except
Azithromycin), Sulfonamides