P H A R M A CE U TI CA L P R EP A R A TI O N S .

ELI X I RS

T H EI R H I STO RY ,
F O R M U LE ,
A ND M ET H O D S
O F PR EPA RA TI O N

I NC LU D I N G

P RA CT I C A L PR OC ESS ES FO R M A K I N G T H E PO PU L AR
EL I X I R S O F T H E P R E EN T D AY , AN D S TH OS E
WH ICH H AV E B EEN O F F I C INA L IN
T H E O LD P H A R M A C O PCEI A S

T O G ET H ER W ITH

A RES U M E O F U NO F F I C I N AL I I
E L X RS F RO M T HE D AY S OF

P ARAC ELS U S

BY j . U . LLO Y D
P r ofe sso r of C h e mi s t r y i n the Ec l ec t i c M ed i c al I tit t
ns u e ; P ro f
ess o r o f

P harmac y i n t h e C i i
nc n n a ti C ol le g e of P h ar mac y ; A u h o r t
of
“
C h em its ry o f M ed i i
c nes , etc., etc .
, e t c.

S E C ON D E D I TI ON

C I NC I NN AT I
R O B E RT C L A R K E C O M PANY
 P REF AC E .

Were p h ar m ac i s ts u n i ted in o
pp os i t i o n to el i x i rs, an d su ffi c i en tl y i nd e

p e n d en t t o w ar r an t th em i n say i n g th at th ey are u n n ecessar y p re

p ar at i o n s,

an d t h at t h ey w o u l d n o t m an u fac t u re d i spe n se th em ; o r co u l d h ar ma
or p
c i sts so i n fl u en c e an d co n t r o l h
p ys i c i an s as to p o s i t i v el
y p re v en t th em fr o m
r i b i n g e l i x i rs or , w e re t h e p ast n u m b ers o f al l o u r h ar m aceu t i c al
p resc ; p
jo u r n al s p osse b
ssed
y , o r re ad i l y access i bl e t o , e ac h an d ev e ry p h a r m a

c i st i n t h e co u n t r y —t h e re w o u l d th en b e n o n ecess i ty fo r , n o r u t i l i t y i n ,

t h e p u b l i cat i o n o f a w o r k u p o n el i x i r s an d t h e m et h o d s o f p re p ar i ng

th em . A t t h e p r esen t t i m e th ere u n d o u b ted l y e x i s ts a d em an d fo r th i s

c l ass of r e ar at i o n s , an d , i n o r d er t o i m ro v e, as w e l l as re tai n , th e i r le
p p p
g i t i m at e t rad e, our p h ar m ac i st s are, in a m eas u re, co m p el l ed to d i spe n se
th e m , as th ey d o d es i re to d i sp l ease t h ei r m ed i cal p at ro n s b y an y i h
n ot

d i cat i o n s o f w h at m i gh t b e co n si d ered as o ffe n s i v e d i c t at i o n S u c h b ei ng .

th e c ase , an d , as a l arg e n u m b er o f t h e h ar m ac i s t s O f th i s c ou n tr y ar e
p
not p ossessors of th e p as t n u m b e rs o f
p h ar m ace u t i cal j o urn al s , w e ha v e
b een i n d u ced to p re
p ar e th i s l i t tl e w or k .

I n p resen t i n g t h ese fo r m u l ae, th e r esu l t of years o f ac t u al l ab o rat o ry

ex per i en ce , an d t h e c are fu l st u d y o f t h e b ack n u m b er s o f al l o u r p h ar m a

c e u t i c al j o u r n al s , we can n o t d o u b t th at th ey w i l l b e v al u ab l e to p h arm a

c i s ts, an d t h at t h e i n v es t me n t w i l l q u i ck l
y r e tu rn t o each p rch aser
u m or e
th an t h e o u t l ay fo r th e b oo k .

U po n th i s q u es t i o n Of e l i x i rs we find our A m e r i can p h ar m ac i st s

g r eat l
y d i v i d ed : so m e d ec i d ed l
y j
O b ec t to th em , no m at ter u n d er w h at
co n si d e rat i o n s o r c i r cu m st an c es , an d o b s ti n at e l r e fu se t o l i s t en t o a fa
y
v o r ab l e w o r d fo r an y o ne o f th e m ; o t h e rs u h o l d th at
p c ar e fu l l
y p p re ared
’
e l i x i r s, i n w h i c h th e d i sag r eeabl e n ess an d o ffe n s i v en ess o f ce r t ai n d r u s
g
en ter i ng i n t o th e i r c o m p os i t i o n are m o re or l ess m ask ed , ar e to be c om

m end ed . N ot u n fr e qu e n tl
y th e O
pp o n e n ts O f el i x i rs ar e q u i t e v i o l en t in
th ei r d e n un c i at i o n of th em , an d m o re esp eci al l y as b e i ng of t w o co m

l
p ex a ch ar ac t er , an d ye t t h ese
. v er
y j
o b e c t o rs w ill fav o r o t h er m i x tu res
an d p re
p ar at i o n s t h a t a r e s t i l l mo re co m p l ex , an d fu l l y as u n s c i en t i fi c as

t u t: m aj o r i ty o f co m
p o u nd e l i x i r s. O n th e o th e r h an d , t h e ad v o cates of
 P REF AC E .

e l i x i rs freq u en tl y asso c i ate i n co m p at i bl es i n t h e i r p re p ar at i on s, th ereb y

r en d er i n g t h e m v al ue l ess . B y t h i s c o u r se t h ey w e ak e n th e c au se th ey
ar e e n d eav o r i n g to s u s tai n, as th e ar t i cl es t h ey to th e ubl ic
p r ese n t p
p ro v e to b e u n re l i ab l e. In ou r O
p i n i o n , th e re i s an i n te r m e d i u m , a co n

ser v at i v e osi ti o n , b et w een th o se w h o u n r ese r v ed l co n d em n an d th ose

p y
w h o i n d i sc r i m i n at el y re c o mm e n d , an d i t w i l l b e fo u n d t h at t h e re ar e

m an y e x cel l en t p h ar m ac i s ts oc c u p yi n g th i s p o si t i o n , w ho arg u e th at ,

w i th j u d g m en t in s el ec t i o n an d sk i l l in m an i p u l ati on , a l i ne o f el i x i r s

m ay b e p r o d u c ed th at w i l l fav o r ab l y c o m p are w i th o th e r se c t i o n s o f

p h ar m acy , an d t h a t i n t h e i r r e ar at i o n as m u c h sc i e n c e an d co m p e
p p
t en ey m ay b e d i sp l aye d as i n th at o f an
y o t h er c l ass o f p h a rm ac e u t i c al s .

I n th e p resen t w o r k w e h av e e n d e av o re d t o p o i n t o u t d efe c ts, as w el l

as i n co m p at i b l e co m b i n a ti o n s, an d t h o u g h a t fi rs t g l an c e th e i m p ressi o n
m ay be co n v eyed th at w e en te r tai n a p o si t i v e h ost i l i ty to el i x i rs, y e t, as

i t m u st b e ad m i t te d by e v ery on e t h at th ere is co n s i d er ab l e r oo m fo r
fr i en d l y p r u n i ng , w e t r u st th at o u r re m ar k s w i l l b e r ecei v ed i n t h e sam e
k i n d sp i r i t as th at i n w h i c h th ey are m ad e , an d th at w e w i l l n o t b e
r ep r oach ed for b ei n g u n n e cessar i l y ce n so ro u s. And , n o tw i th s tan d i n
g t h at

our c r i ti c i sm s m ay ap p ear to b e se v e r e , w e b el i ev e th e m t o b e fai r an d

j
u n p r e u d i c ed , an d o f s u ch a c h a rac te r t h at b o th t h e ad v oc a t e an d th e

o
pp o n en t o f A m er i c an El i x i rs
”
may d er i v e b o th sat i sfac ti o n an d b en e fi t
from th ei r p er usal . J . U . L.

P R EF A C E T O T H E S ECO N D ED I T I O N .

W i th i n t h ree m on th s fro m t h e appe ar an ce o f th e fi rs t ed i t i o n of

th i s b oo k , th e p u b l i sh e rs h av e n o t i fi ed us t h at a sec o n d i s d em an d ed .

Th i s en c o u rag es u s t o b el i ev e th at our w ork i s not w h ol l y u n ap

p rec i at ed .

We i ssued th e fi rst ed i t i o n w i t h m i sg i v i n gs . We fe ar ed t h at th e c l ass o f

re ar at i on s em b r aced u n d er t h e n am e e l i x i r w o u l d n o t p ro v e su ffi c i en t l y
p p
i n t eres t i n g an d v al u ab l e t o w ar ran t t h e p u b l i c at i o n of a w o r k d ev o te d

e x cl u si v e l y to th i s su b j ec t . T h en , t oo , v ar i o u s
p ro b l e ms ar ose w h en w e

at tem p ted to u n tang l e th e i n t r i c ate el i x ir h i s t o r y , to r e c o n ci l e i n co m p at

i bl es, to c r i t i ci se j u d i c i o u sl y , an d to p re v en t o u r
p j
r e u d i ces fr o m o ccasi o n

al l y i n fl u en c i n g o u r re m ar k s. T h ese an d o th er p o i n t s r en d ered o u r l ab o r
by no m eans p l easan t H o w ev er , t h e fav or w i th w h i c h th e fi rs t ed i ti o n
.

h as b een r ecei v ed , an d t h e m an v w o r d s o f app ro v al reg ar d i ng i t , l e ad u s

t o b el i ev e th at o u r l ab o r h as n ot been l o s t . We co r d i al l y i n v i t e p h ar m a
c i s ts t o n o t i fy u s o f an y t ro u bl eso m e fo r m u l a i n th i s b o o k , t o co r re s p o n d
w i th u s co n c e r n i n g el i x i r s i n l o c al u se , if o m i t te d b y i t, an d t o ad v i se u s

of an y h i stor i cal o v ersi gh t . P l ease n o te o u r re m ar k s in A d d en d a

 E L I X I RS .

T H R O U G H th e o u r te sy o f M r C h arl es Ri ce t o w h o m
c .
,

appl i c at io n w as m ad e b y t h e a u t h or fo r n o t e s 0 11 t h e d e

r i v at i o n o f t h e w ord el ixi r w e are e n abl e d t o pre sen t

,

h i s repl y v erb at i m an d i n add i t io n pr e s u m e t o s ay a fe w

,

w ord s c o n c er n i n g t h e elixi r o f t h e p ast an d o f t h e

pre se nt w hi ch m ay i n t er e st th e re ade r
,
.

D EAR F R I EN D — I n repl y t o y o u r i n q u i r y c o n cer n i ng

“
t h e e ty m olog y o f t h e w o r d e lixi r I w o u ld say t h at
,

t h e w ord 1 5 proxi m at el y d e ri v ed fro m t h e A 1 ab i c

b e i n g c o m po se d o f t h e ar t i c l e J"( a "or l ) a n d
3”
M
( d l c

u f j ( z k sz r
) The l at t e r i s a n a r abi c i z e d for m o f t h e
f
.

Gr eek w ord E jp
r wv
( x m m t
, h e 7; ( ) z bei n g pro n o u n c ed
l ike ee) Thi s de ri v at io n w as fi r st r e cog n iz e d an d an
.

n o u nc e d b y Fl e i s ch e r i n 1 8 3 9 b u t i t s e e m s t o h av e be e n
,

o v e rlooked b y l at e r w ri t er s H e r m an n K opp t h e h i s
.
,

t ori an O f C h e m i s t r y i n h i s , B ei t r ag e z u r G esch i c h t e d e r
C h e m i e ( 1 8 69 p ,
. q u o t es a n u m b e r O f p assag e s fro m
l at e r Greek au t h or s an d fro m w ri t e r s o f t h e al ch e m i s t i c
s c hool , i n w h i c h h e sho w e d t h at t h e Gre e k fépw v an d
t h e A r abi c cl — z k s i r w e r e i d e n t i c al i n s i n i fi c at io n b u t h e
’

g ,

failed t o n o t i c e t heir e t y m ologi c al id e n ti t y . The A r ab s

can n o t pro no u nc e an i n i t i al E ( )
x w i t h o u t pl ac i n g an a u x
6 EL I X IR S .

i l i ary o r s u ppor t i n g v o w el i n fro n t O f th e do u ble c o ns o

n n t t h u s m ak i n g z ks i r
a ,
l Th i s pe c u li ari ty o f av oid i n g
.

a n i n i t i al do u b l e c o n s o n an t ( s c sp o r s al s o i n
e tc
) c c u , , .

o t h e r l an g u ag es fo r i n s tanc e i n S p an i sh w her e w e h av e
, ,

es er a , r s cz l a , es i i
'

p p r t u, e t c.

Th e w ord f jp ,
w
r v i n m ed i c al w ork s ,
m e ans any d ry
po w der ( fro m d ry ) s u c h as i s u sed fo r d u s t i n g
,

w o u nd s .I n al c h e m y i t w as u sed to d e n o t e t h e m agi c al
t r an sfor m at io n po w d e r so m u c h s o u gh t aft e r a pi n
,
ch o f ,

w hi c h w o u ld c o n v e r t a w hole m as s o f b as e m e t al i n t o

g old .[A si a i n t h i s s e n se i s id e n t i c a l w,
i t.h a n o t her i n

t e rest i ng Ar abi c t er m v i z ,
fro m w
.
,
h i ch
o u r w ord c z em st ry i s d e ri v ed
/ zi b u t w hi c h i s i t sel f d e ,

ri v ed fro m t h e Gr eek ) Thi s w as al s o applie d t o a c o n

.

c re t e t hi n g n am el y t h e s u b s t an c e s rnp p o se d t o be c ap a
, ,

b l e o f m aki n g gold For i n s tan c e w e m e e t s u c h expre s

.
,

AM M “
s io n s as L Q M (g l m i y )
d h m ki g f
‘
a n a l y t e a
-
n o ,

M
“
the ki m iya and y M m zatu l z k s fr
’

, (g ) t h e -

m aki ng o f t h e i k si r bo t h m e an i n g th e am e t h i n g
,
s
.

“
I n l at e r t e c h n i c al l a n g u age
, Elixi r w as u sed t o de ,

n o t e v ar io u s pr e p a r at io n s m ore o r l e s s al c h e m i s t i c It .

w as fo r i n s t an c e s y n o n v m o u s w i t h
, ,
L iq u id Ti nc t u r e ,

t h e fi r s t s t e p i n t h e pre p ar at i o n o f t h e philo s oph e r s

’ ’

s t o n e ; an d t h e re w as a u h i t e a n d a r e d e l ixi r d i s t i n
'

g u i sh e d O
. r i t d esi ,g n a t ed an y c o m po u n d pr e p ar at io n

“
o f s u ppo s ed s u bli m e proper t i e s rep u t ed t o prolo n g
”

li fe an d t o w ard O ff d i s e ase .

S i n cerel y y o u r s ,

C H AR L ES RI C E .

By re ferri n g t o t h e le t t e r O f M r Ri ce i t w ill b e . s ee n

th at at an e arl y period t h e t er m e lixir d es ig n at ed th e

 EL I X I R S .
7

m agi c al t r ansfor m at io n po w d e r S O m u c h so u gh t aft e r , ,

a pi n c h o f w h i c h w o u ld c o n v er t a w hole m as s o f b as e
“
m e t al i n t o gold A ft er w ard t h e w ord w as u sed t o
.

d e n o te v ario us prep ar at i o n s m or e o r le ss al che m i s ti c ,

”

an d i t i s t o be pr e s u m e d t h at c u r i o u s or po t e n t l iq u id s

w e re gr ad u all y i n t rod u c e d an d i n c l u ded am o n g po w d er s .

Fi n all y t h e w ord e lixi r w as applied o nl y t o liq u id s b u t

, ,

t he s e l ike t h e origi n al m agi c al p o w der w e r e s u ppo s e d

, ,

t o po ssess t h e po w e r o f t r an s m u t i n g b as e m e t al s i n t o
n obl e m e t al s .

M r R i c e s tat e s t h at p ar t i c u l ar e m p h asi s w as o nce

.

pl aced o n a w hi t e an d a r e d el ixi r Fro m a c u rio u s l i t .

t l e w ork i n o u r po s se ss io n b e ari n g d at e 1 6 8 2 w e p re, ,

s e n t fo r t h e re ad e r s i n s p e c t io n a fac s i m ile o f t h e pro

’
-
, ,

c e s se s re c o m m e n d e d fo r m ak i n g t he se p rep ar at io n s an d ,

t h at t h e q u ai n t for m u l ae m ay b e re n d e red m or e i n t el l i g i

b l e w e gi v e a fac s i m i l e o f a t abl e w h i c h expl ai n s th e

, _
-

ch ar act er s e m plo y ed i n t h e book as follo w s ,

“A n Expli c atio n of C h ar ac ter s u edf i n t hi s B o o k .

A F A q u a F or t i s
. .
.

S i l v er . A R A q u a R eg i s
. . .

Wz u e
’

I r on . S V . . Sp i r i t qf .

Al S u bl z m ate
’

er c u r
y
)
I
. .

i
' '

7 a
; t er .
1 I

( P r ecz
p z t a t e.

Ven u s .
2
a a a A m alg am a .

L ea d . v u
’
a t er .

A n t z m ony
'

. A F ire .

S al a r m on fa r .

1 . T h i s n am e w as ap p l i ed to T i n w h en th e b ook w as w ri t ten .

2 . T h i s n am e w as app l i ed to C op per w h en th e b ook w as w ri tten .

8 EL I X IR S .

E l i x i r A l bu m .

U bl i m e 2: t hr ee t i m es fr o m V i t r i o l S al t p e tr e th e n an d -
,

i n h o t S an d fi x i t fo t h at i n ftro n g h e at i t m ay n o t
,

r rfe w hi c h m a b e p e r fo r m e d i n t h r e e w ee k s t i m e : T h e n
, y
C al c i n e i t i n a c l o s e R e v e r b e r at o ry A an d i t w ill be ready .

fo r fo l u t i o n . T h e n tak e t h e W a te r w hi c h d i fti l l e d o v er
i n S u bli m i n g t h e b an d di s so l v e i n i t a li ttl e at an d
,
e
,

Q a m ate ; w i t h t hi s fo l u t i o n m i x C al c i n ed V i t ri o l t o t h e thi c k
n ess o f H o n e
y d i g e ft i u
, fi m o o n e an d t w e n t
y d a
y s : T h e n

d i ftil l b y d e g r e e s a li t t l e at a t i m e ( fo r i t y i e l d e t h a v e ry
fi e ry S piri t ) l e t t h e R e c i p i e n t b e l ar g e W h e n al l i s c o m e
, .

o v e r t h at w ill r e c t i fi e i t ; t h e n i n t hi s S p iri t d i ffo l v e t h e

,

afo r e fai d fi x ed 9 fo i s t h e Al eu l r u u m pr e p ar e d
-
,
/ .

T h e n ta k e a w hi t e C al x o f 1 1 p o u r u p o n i t fo m u c h ,

o f t hi s Al eu i r u u m as w ill c o v e r i t l i t fi an d e i g h t
/ et ,

d ay s as b e fo r e R e p eat thi s t ill t h e C al x w ill t ak e i n n o

.

m o re o f t h e faid t h e n l e t i t {l an d t ill i t b e

co m e s fi r ft b l a c k an d t h e n w hi te S u bli m i n g i t se l f a b o v e
, ,

t h e C ap u t M or t u u m fr o m w hi c h c ar e fu ll y fe p arate t h e
,

w hi te an d t h at i s S u lp h u r n a t u r e yov i s w hi c h p u t i n to
, ,

a li t t l e M at r afs an d fi x i t ( w hi c h m ay a l fo b e d o n e b y
fr eq u e n t m at i o n ) ; m ak e al fo S u lp /z u r u a z u r a: D i n th e
‘
a

fame m an n e r an d w i t h t h e s am e M enfi r u u m w hi c h d i f
, ,

fo l v e i n to O y l i n B w i t h w h i c h i m b i b e t h e said S u lp /z u r
.
,

00 1 s u n t il i t b e u b l e a n d t h e n i t w ll t r an f
f
7 f i
'

n at a r re 1 ,

m u te i t i n t o D .
 L LI X I R S 9

E l i xir R u é r um .

A k e V i tri o l of 9 w e p ll i fi ed b
ur
y S o l u t i o n s an d C o

ag u l at i o n s u n i t e i t w i t h L i q u o r o f Q
,
rn a t e an d a
fit e
,

t h e n d i s t ill a v fr o m i t i n A fne s ; t h e n h av i n g fl o o d ( C ol d )
t w e n ty fo u r h o ur s d i fti l l m o r e V fr o m i t
-
,
R e p e at t hi s
.

u n t il t h e r e m a i n i n g M at t e r b e w e ll b r o k e n ; t h e n j o y u al l

t h e d i ft i l l e d w at e r s t o i t ag ai n an d d i g e ft i t i u j z m o fo r 40
'

d ay s : T h e n d i ft i l l i ts S piri t w i t h vv h i c h i m b i b e t h e r e m ai n
,
‘

i n g Ear t h ; d ry i t w i th a g e n t l e h e a t t h e n i m b i b e ag ai n an d
, ,

d r y as b e fo r e : R e p e at t hi s t ill t h e E ar t h h a t h i m b i b e d al l
i ts v T h e n d i ft i l l i t an d y o u fh al l h av e a P h i l o fo p h i c al c
.
, ,

an d w h at S u b l i m e t h i s t h e S u lph u r w hi c h k e e p ap ar t
'

.
,

R e p eat t h e i m b i b at i o n an d d i fti l l at i o n t ill n o m o r e S u lph u r

,

w ill afcen d ; w i th t hi s S u l p h u r i m b ib e h al f i ts w e i gh t o f t h e
Q p
,
u t t h e m i n t o a M a t r a fs w ,
h i ch S e al H e r m e t i c all
y ,

an d fi x t h e m t o g e t h e r ; an d t hi s “ fo r k m u s t b e r e p e a t e d
fo u r t i m e s e v e ry t i m e w i t h th e fam e pr o p o r t i o n o f t h e
,

faid P h i l o fo p h i c al T h e n fi x t hi s M at te r i n a V e s sel
S e al e d H er m e t i c all y b y d e g r ee s o f A an d al l th e c o l r s ,
o

w ill ap p e ar o n e afte r an o t h e r u n t il t h ey b e c o m e w hi t e
, ,

an d l a s t l t a n i n c o m b u sti b l e r e d
, y o,
.

T ak e o n e p ar t o f t hi s r e d P o w d e r c ast i t u p o n t e n ,

p ar ts o f S u b li m ed e fe t i t to p u tre fi e fo r th irty d ay s a n d
, ,

i t w ill b ec o m e O y l W hi c h b e i n g P r oj e c t e d u p o n b oy l i n g
,

Q w ill tr an s m u t e i t i n to p u r e 9
,
.

T h e fai d re d P o w d e r b e i n g i n fu fed i n W i n e o v e r N i g h t ,

an d dr an k i n t h e M o r n i n g C u r e t h m o ft D i se as e s i n M an s
,

B ody .
10 EL1 x1 Rs .

I t w i ll be ob ser v e d t h at t h e w hi t e elixi r El ixi r A l ,

bum ,
c an o n l y prod u c e s i l v er w hi le t h e red elixi r , ,

Elixi r R u br u m w ill t r an s mu t e m er c u ry i n t o p u re
,

gold W e c all at t e n t i o n t o t h e red po w de r w h i c h i s

.

for m e d n e ar t h e c o m ple t io n o f th e pro c e ss i n m aki n g

elixi r r u br u m an d w h i c h i s u sed t o p r e p are t h e m agi
,

c al oyl a nd t o t h e asse r t io n t h at t h i s s am e red p o w

”
'

der c u re th m o s t d i se ases i n m an s bod y H er e w e ’

.

h av e an appro ac h to t h e elixi r o f li fe ( elixi r v i t ae) o f t h e

al c he m i s t s t og e ther w i t h t h e p rop e r t i e s as c rib e d t o t h e
,
’

ph i lo soph e r s s t o n e I n t h i s c o n n e c t io n a q u o t at io n
.
,

fro m t h e w ri t i ng s O f t h at cel eb rat e d au t h o r o f t h e eigh

'

t e e n t h c e n t u r y B oerh aav e i s o f i n t er e s t c o n c er n i n g t h e
, ,

e lixi r v i t ae w h i c h i n B o e rh aav e s l ang u age w as o ne o f

’

t h e c hi e f t hi n g s w hi c h t h e al c he m i s t s pro m i s e Th e ir .

ai m w as t o di s c o v er an ar t i fi c i a l bod y O f s u c h v i r t u e
an d e ffi cac y as t h at bei n g appli e d t o an y bod y o f an y
,

o f t h e t hr e e k i n gdo m s i t s h al l i m pro v e i t s n at u r al i nh e
,

re n t v i rt u es so as t o m ake i t t h e m o st p e r fe c t t h i ng i n
,

i t s ki n d .Th u s fo r i ns t an c e i f applied t o t h e h u m an
, ,

bod y i t w ill b e c o m e an u n i v e r sal m e d i c i n e and m ake

, ,

s uch a c h a ng e bo t h i n t h e s ol id an d fl u i d p ar t s t h e r e o f
, ,

as s h all re n d e r i t per fe c t l y s o u n d a n d e v e n m ai n t ai n i t ,

i n t h at s t at e u n t i l t h e p ar t s b e i n g s lo w l y w or n a w ay an d
,

s pe n t ,d e at h g e nt l y an d w i tho u t a st r u g gle t ake s p o s

s e s s io n .

W e fi nd t h e r e for e t h at th e al ch e m i st s b y th e t e r m
'

, , ,

e lixi r ,i n t e n ded t o d e s ig nat e s u b s t an ce s w h i c h c o u ld

e i th e r c o n v e r t b as e m e t al s i n t o gold or s il v er o r c o u ld ,

prolo n g li fe and h e al t h e s i c k or e m bod y bo t h prop e r ,

t ie s ; an d al s o t h at t h i s s u b s t an c e m igh t b e ei t her a
,

l iq u i d o r a s ol i d W e d o n o t g e n e r all y acc red i t t h e

.

al c h e m i s t s w i t h a d e s i r e t o h e a l d i s e as e s aft er t h e m an
 E LI X I R S .

n er o f ph y s i c i an s o f t h e pr ese n t d ay and do u b t le ss th e ,

m aj ori t y s e ar c h e d o n l y fo r ri c h e s H o w e v e r w hil e t h ey
.
,

m o s t l y d e s i red gold a n d s i l v e r t h e y re ali z ed t h at t h e

,

u s e o f o n l y an ord i n ar y a m o u n t c o u ld b e e nj o y ed i n t h e

u s u al li fe t i m e allo tt ed t o man A g a i n m an y o f t h e se
.
,

i n fat u at e d m e n w ere o n t h e bri n k o f th e g r av e w he n

t h e i r hope s se e m e d m o s t likel y t o be re ali z ed an d o f ,

v i t al i m p o r t an c e w o u ld be t h e po sse ss io n o f a s u b s tan c e

w h i ch c o u ld p rolo n g l i fe H e nce w e fi n d t h at s o m e o f
.

t he m w ere se ar c hi n g d i re c t l y fo r gold o r t h e p h i l o so ,

h e r s s t o n e b y m e an s O f w h i c h al l b as e m e t al c o u ld be
’

p
c h an ged i n t o gold w h i le o t h e r s d es i r e d m o s t t h e e lixi r
,

o f l i fe e lixi r v i t ze
,
w h i ch c o u ld e x t e n d li fe an d c h an g e
,

O ld a e i n t o y o u t h I n d ee d as i n c e n t i v es t o t h e i r l a
g .
,

bor s w e r e t h e as ser t io ns t h at t h es e w o nde r fu l elixi r s

h ad bee n di s c o v e red b y o t h e r s a nd w e q u o t e fro m ,

The B i r th O f C h e m i st r y t h at S Tho m as A q u i n as
”
.

w as like h i s m ast e r ( A lb e r t u s M ag n u s )
,
a m agi c i a n , .

W e are t old t h at be t w e e n t h e m t h ey c o nst r u c te d a

br aze n s tat u e w hi c h A lb e r t u s an i m at e d w i t h h i s el i x i r
,

i tw
”
v .

Cul i r ed t h at h e c o n v er ted fi fty th o u s an d

ass e t
“

p o u n d s w e igh t O f b as e m e tal s i n t o gold a n d i s s aid t o ,

h av e fu r n i s h e d h i s ki n g w i t h s i x m il l io n s o f m o n ey .

P ar ace l s u s ( bor n 1 4 9 3 d i e d 1 54 1 ) i s g e n e r all y acc re d i t e d

,

w i t h i n st i t u t i n g a n e w e r a i n t h e s t u d y fo r h e w as pr o m ,

i n c u t i n sho w i n g t h at al ch e m y w h i c h fl o u r i h ed i n h i s
,
~

d ay an d o f w h i c h he w as a z e alo u s st u de n t c o u ld b e o f
, ,

v al u e t o ph y s i c i an s an d t h at t h e k n o w l e dg e d e ri v e d
,

fro m t h e i r i n v e st ig at i o n s c o u l d b e t u r n e d t o ad v an t age
i n t h e t r e at m e n t O f d i s e as e L i k e t h e O l d al c h e m i s t s
.
,

h o w e v e r Par ace l s u s s u rro u n d e d h i s p ro c e s s w i t h m y s

,

t e r i o u s e x pr e s s io n s an d d i sj oi n t e d t h e m u n t il t h e y w ere
,
 ELI X I RS .

i nc o m prehe ns ible
‘
, H e origi n at ed t h e
Elixi r Propri e
“
t at i s s t at i n g t h at i t w as s o po t e n t as t o c o nt i n u e
”

h e al t h an d lo n g l i fe t o t h e u t m o s t po s s ible l i m i t s ( B oer
l z a a v e) Th i s w o nder fu l el ixi r w as c o nc o c t e d b y c u m
.

b e rso m e pro c e ss e s fro m s u ch s i m p l e s as saffro n alo e s , ,

a nd m y rrh an d n o t w i t h st an di ng P ar ace l s u s c l ai m e d t h at
,

b y u s i ng t he v au n t e d elixi r propri e tat i s h e sh o u ld l i v e

as lo n g as M e t h u s el ah h e d ied a brok e n w r e c k i n h i s
”
,

for ty se v e n t h y e ar
-
We fi n d t h at t hi s e lixi r w hi ch i s a
.
,

re cord o f P ar ac el s u s ego t i s m h as b e e n r ec og n i z e d i n’

o u r di spe ns at ori es an d i n t h e old e r ph ar m ac op oe i as w i t h ,

m ore o r le ss al te r at io n e v e n t o t h e pr e se n t d ay Boe r
, .

h aav e g av e fi v e d i ffe re nt pro c es se s fo r m aki ng i t e ac h ,

O f w h i c h prod u ce d i n h i s opi n i o n a m o st p o t e n t re m
, ,

ed y . A s a c u rio s i t y an d t o i ll u s t r ate t h e w o n d e r fu l
,

p roper t ie s at t ri b u t e d t o t h e s e c o n co c t io n s i n t ho se d ay s ,

an d t o t h e v i r t u e s O f w hi c h e v e n s u c h a c h e m i s t as

B oerh aav e c o u ld c er t i fy w e r e prod u c e fro m h i s El e ,

Paracel su s b o r ro w ed free l y fro m t h o se w h o p reced ed hi m ,

u nd o u b ted l y

and fai l ed t o c red i t t h em fo r su c h i nst r u c t i o n G o od au t h o r i t i e s t rac e t he

.

ap pl i c at i o n of ch em i s t ry i n t h e h eal i n g of di s eases far b ack o f th e d ay of

P aracel su s M C C l e rc t hi nk s t h e re
. . are i n d i c at i o n s o f c he m i c al m ed i
c i n es i n T h ad de u s the F l o ren t i n e, w h o l i v ed i n t h e t h i r t ee n t h y i
c en t u r
n ,

A l ber tu s M agn u s F ri ar Baco n an d L ane H o l l an d u s

, , . H el m o n t h as t ak en
ai ns t o sh o w t h at B as i l V al e n t i ne w as p r i o r t o P arace l su s b y a h u nd red
p
e a rs O f Basi l V al e n t i ne t he same a u t h o r rem ark s : H e
y
w o ul d see m to h av e b e en t he fi rst w h o appl i e d c h em i s t ry t o m ed i c i ne ; fo r
a ft er ev ery re
p p ar at i o n he n ev er fai l s t o gi v e so m e m ed i i n al u se t l e reo f
t .
.

Paracel su s, I l e l mo n t , t he e ld e r L m e ry, an d man y o t h e r s

e
of mod er n fame,
owe a re at art o f n h at i s v al u ab l e in t h em t o t h i s au t h o r so t hat i t i s
g p
n o t w i t ho u t reas o n t hat he i s j ud g e d the fa h er
'
of t he m o d er n cl e m i s t s aud
th e fo u nd e r f t h e c h e m i cal ph ar mac y
o A b o u t t he m i d d l e o f t h e fi ft een t h
.

cen t u ry l i v ed B asi l V al e n t i n e a G e r m an B e n e d i c t i n e m o n k
, h o l ed t he .

w ay t o t h e i n t e rn al ad m i n i t r at i o n o f m e t al l i c m ed i c i n e s by a v al i e ty o f ex
ri men t s o n o f an ti mo ny
”
pe t h e n at ure
 EL I X IR S . 13

m e nta C h e m i aa ,
w h i c h w as p u bl i shed in 1 72 4 , t h e fo r
m ul a an d u s s o f e h is

ELI x I R P R O P RI ET AT I S W IT H D I ST I LLED V I N EGA R .

T ak e c h o i c e al oes , s affro n , an d m y rr h , o f eac h ha f l an o u n c e ,

c u t a nd b r u i se t h e m , p u t t h e m i n t o a t a l l b o l t h e ad , p o u r t w e n t y -

t i m es t he i r o w n w e i gh t o f t h e s t ro ng es t d i s t i l l ed v i n egar t h e r eo n

l e t t h em si m m er t og e t h e r in ou r l i t t l e w oo d e n fu r nace fo r t w el v e
h o u rs n o w s u fl er t h e w h o l e t o re s t , t h a t t h e fe m ay s u b si d e ,
'

ces

an d ge n t l y s t r a i n o ff t h e p u re l i q u o r t h ro ugh l i n en ; p u t h a l f
a thi n

th e q u an t i t y o f d i s ti l l ed v i n egar t o t h e re m ai n d e r , b o i l a n d p ro

c e ed as b efo re , a n d t h ro w aw a y t h e fa c e s M i x t h e t wo t i n c t ure s
.

t oge t h e r , a n d d i s t i l w i th a gen tl e fi r e t 1 l l t h e w h o l e i s t h i c k e n ed t o
a t h i rd ; k ee p t h e v i n eg ar t h at c o m es o v er fo r th e sa me us e an d

w h at re m ai n s b e h i n d i s th e E l i x i r P r op r i etat i s , m ad e w i t h d i s
l
t i l ed v i n egar .

T H E U S ES .

Th u s w e O b t ai n an ac i d , a ro m at i c m ed i c i ne , of at in
gr e u se

th e p r ac t i ce o f h
p y s i c fo r w h e n ex t e r n al l y ap pl i e d , it l
C e an s e s a n d

h eal s p u t r i d , s i n u o u s , an d fi s t u l o u s O l d u l c e rs d e fe n d s t h e p art s ,

fro m p u t re fac t i o n , an d p r eser v e s th e m b y a t r u e e m b al m i ng v i r t u e

l
i t al so h e a s u l ce r s , a n d c u r es g an g re n es i n t h e l i ps , to n g u e , pal at e ,
an d j aw s . I t h as t h e s am e e ffe c t si n t h e fi rs t p as sag es , w h en u sed
i n ter n al l y , as o ften as t re fi e d m at te r , c o rr u t e d b i l e t d
p u
p ,
co n c r e e

p h l eg m , w o r m s , a n d n u m b e rl e s s d i s te m p e rs p ro c e ed i ng fr o m t h e se
fo u r c au s es , ar e l o d ge d or s ea te d th erei n . Agai n ,
i t h as n earl y

t h e sa m e e ffe c ts i n t h e b l o o d an d v i s cer a , as m ay e asi l y appe ar

fr o m k n o w i ng th e v i r t ues o f t h e t h r ee i n gre d i e n ts w h e n d i s so l v ed i n
a s u b t i l e v i n egar . It is to be t ak e n in a m o rn i ng u po n a n e m pt y

s t o m ac h , at l eas t t w e l ve h o u rs a ft e r eatm g ; 1t 1s g i v e n fr o m a

d rac h m to t w o or t h r ee fo r a d o se i n s w ee t w i ne o r m e ad , or th e
l ik e, w al k i n g aft er it, h a v i n g t h e b e l l y g e n tl y r u b b e d
or I f tak e n .

in a l arge r d o se , a n d w i t h a s o m e u h at c oo l e r r e i m e n i t al w a s
g , y
p g
u r e s ; i f i n a l es s d o s e , a n d o ft e n r e p e at e d ,
it l
c ean s es th e b l o od
by sec re t i n g t h i c k u r i n e ; an d ge n e ral l y p e r fo r m s b o t h t h e se op
I4 EL1 x 1 R s .

e rati on s s uc ce ssi v el y. B u t i f tak e n p l en t ifu ll y, wh il e th e p ati en t

i s i n b ed an d th e b od y w e l l c o v e re d , i t ac ts as an e x cel l e n t s u d o
r i fl e ; a n d a ft er w a rd u s u al l y p u rge s an d ro v es d i u re t i c , a n d t h u s
p ,

b eco m e s v er
y use fu l w h ence I c o nce i ve t hat t h i s i s t h e b es t ac i d

el i x i r p p ro r i etat i s , go o d in n u m e r o us c ases , an d a t t h e s am e t i m e

s afe

P arace l s us d ecl ared t h at an e l i xi r m ad e of al oes , s affro n , an d

m yrr h w o u ld p ro v e a v i x i fyi ng an d p r e s e r v i
ng b al sa m , ab l e to
con t i n ue h eal th an d l o ng l i fe t o t h e u t m os t p o ss i b e l l i m i ts ; an d

h en ce h e i t b y a l o ft y t i t l e t h e e l i x i r o f p ro p ri e t y t o m an ,
c al l s

b ut c o n c e al e d t h e p rep ara t i o n , i n w h i c h H el m o n t asse r ts t h e al

c ah es t is tu re d .
re
q

Thro u gh eigh t ee nt h c e nt u ry elixi r s w e re n u m er

the
o us ,
a n d al tho u gh t h e i r for m e r a l c h e m i s t i c prop e r t i e s

w ere c as t as ide ph y s i c i a n s s e e m e d t o at t rib u t e t o t h e m

,

v i r t u e s s c ar cel y l e s s t h a n t h o s e as c ri b e d t o t h e fam o u s

el ixi r v i ta The y w ere al so s u rro u n d ed w i t h m y s te rie s

‘

.
,

an d t h e i r c o m po s i t i o n s w e r e m o s t c arefu ll y c o n c e al e d .

Pro m i ne nt ph y s i ci ans i n di v id u al ized t h e m sel v e s b y at

t ac hi n g t h e i r nam e s t o t i n c t u r e s O f herb s ex t r ac te d w i t h
s pi ri t o f w i n e or w i t h ac id s ol u t io ns an d t h ese n am e s
, ,

h av e b e e n h an ded do w n t o u s an d are st ill i n u se I t m u st .

n o t be i n ferred ho w e v e r t h at t h es e m e n g av e t h e i r t re a
, ,

s u re s ope n l y t o c o m p e t i t o r s fo r w e fi n d t h at gre at c ar e,

w as e m plo y ed t o c o v e r t h e i r pro c e sse s an d t o c o n c e al

t h e c o n st i t u e n t s o f th e se c o m po u n d s an d at t h e pr e s e n t ,

d ay w e fi n d i t d i fli c u l t t o d e c ide as t o t h e au th e n t i c i ty
‘

M
’

O f s u c h as D affe s El i x i r e l m o n t s Eli x ir sich t s

'

y H ’
. y n ,

Elixi r V i gan i s Elixi r e t e e t e I n de e d m an y o f t h e O l d

,
’

, .
, .
,

w or k s gi v e se v e r al for m u l a fo r prep ari n g a s i n g l e e li x i r ,

an d O ft e n all t h e pro c e s s e s w e r e i m pr ac t i c abl e Th u s w e .

fi n d t h at w i t h e ac h r e v i s i o n o f t h e O lder ph ar m ac op oei as
an d d i s p e n s at ori e s t h e s e for m u l a h av e b e e n al te red
an d s i m pli fied an d as t h e o u t c o m e w e re fe r t o s o m e o f
,
 EL 1 x 1 R s . 1 5

our w ell k n o w n t i nct u r es w h i c h h av e spr u ng fro m

-
, and

are m odi fi c at io ns o f a nc i e n t e lixir s

ELI X I R S A LU T I S gav e us C o m p o u n d T i nc t ure o f S e n n a .

ELI X I R P A R EGO R I C U M gav e us C am p h o rat ed T i n c t u re o f O p i um .

ELI X I R P R O P R I ET A I C o m p o u n d T i n c t ure of A l o es
’
IS
’

ga v e u s .

ELI X I R ST O M A C H I C U M gav e u s C o m p o u n d T i nc t u re o f G e n t i an .

EL I X I R S A C R U M gav e us T i n c t u re o f R h ub arb an d Al oes .

Wi th o ne ex cep t io n t h e n am e elixi r h as be co m e o b so
l e t e w i t h t h e foregoi n g t i n ct u re s an d t h at o n e p a r eg or i c
, , ,

w i ll d o u b t le s s i n a m ode r at e peri od O f t i m e exi st as a

, ,

r e li c O f h i s t or y .

The e lixi r o f t h e period w e h av e j u s t co ns i d e r e d w as

i n re ali t y a c o m po u n d t i n c t u re o r a m od ifi cat io n O f ,

w h at w e c al l a c o m po u n d t i n c t u r e H oop e r s M e d i cal
’

D i ct i o n ar y o f 1 8 2 0 d e fi n e s t h e e l i x i r as a t e r m fo r
m erl y appl ied t o m a ny p rep ar at i o n s s i m il ar t o c o m po u n d
t i nc t u r es We fi n d al s o t h at t h e O l d e lixi r s w e r e d i s
.
, ,

ag r e e abl e an d bi t t e r Th e re w as no de s i re t o r e n d e r
.

t he m pl e as an t ; i n deed t h e ai m s ee m ed t o b e t h e c o n
,

c o c t io n o f m ix t u re s as n au s e at i n g as po s s i bl e a n d t h e ,

ph y s i c i an w h o c o u ld prod u c e t h e n ast ie st an d w h i c h ,

w e r e follo w e d b y t h e m o st s e v e r e t or t u re t o t h e p at i e n t ,

w as t h e be st m an H i s m o tt o m igh t w ell h av e be e n
.

I p uk e , I p u rge , I s w eat em ,
’

A n d i f th e y d i e , I l e t em
’ ”
.

In c o n ne ct io n w i th t hi s ph ase o f t h e e lixi r q u e stio n ,

w e fi n d t h at o f t h e el ixi r s n am e d i n t h e N e w D i sp e n
s at or y L o n do n 1 770 b u t o n e c o n t ai n ed s u g ar or any
”

, , ,

for m o f s w e e t e n i n g an d th at w as s i m pl y m e n t io n e d as
,

an O b s ole t e p r e p ar at io n Th i s v ie w o f t h e elixir i s s t i ll
.
 6 EL 1x 1 RS .

p re v ale n t i n E u rope and t h e Ger m an Ph arm aco p a i a

,

o f 1 8 70 re c og n i z e s t w el v e p rep ar at io ns u n d e r t h e n a m e

o f e lixi r n o n e o f w h i c h are s w e e t e n ed
,
The id e a ac .

c e p t e d i n o u r c o n t r y at t h e pr e s e n t t i m e reg ard i ng w h a t
u
s ho u ld b e t h e at t ri b u t e s O f an e lixi r i s s t ri c t l y an A m e ri

c an i si n The t e r m Cor d i al w o u ld b et t e r de fi ne t h e
.

s w e e t e n ed an d fl av ored p h ar m ac e u t i cal s w h i ch w e s h al l

n o w c o n s i der as

A M ER I C AN EL I X IR S .

The fi r st o f t h ese p r e p ar at io ns w h i c h t h e w ri t er c an
r e c al l w as t h ro w n u po n t h e m ark e t i n t his c i ty ( C i n c i n
“
n at i ) abo u t 1 8 6 2 u n d e r t h e n am e
, C ord i al Elixi r o f
C ali sa y a I t w as O f a b e a u t i fu l re d c olor n i c e l y fl a ,

v o re d a nd v er y pl e asan t t o t h e t ast e
, an d i t w as t h e
,

fo r e r u n n e r or at l e as t a m o n g t h e fi r s t o f t h e li n e O f
, ,

ph ar m ac e u t i c al s s u b se q u e n tl y s c at t ered s o ab u n d an tl y
o v er o u r c o u n t r y an d w h i c h a re v e ry fa m ili ar at t h e
“
pre se n t d ay A ft e r w ard t h e Elixi r o f C ali say a and
.

P y ropho sph at e O f I ro n app e ared an d t h e n C ali s ay a , ,

P y ropho sph at e O f I ro n an d S t r y c h n i n e S oo n t r av e l
.

l i ng ag e n t s fo r ph ar m ace u t i c al h o u ses b eg an t o c o u r t
ph y s i c i a ns an d s oli c i t t h e m t o s pe c i fy p ar t i c u l ar br an d s
w he n p r e s c ri bi ng t h u s n e c e ss i t at i ng d u pli c at e s u p o n t h e
,
’

apo t h e c ari e s s h e l v es O f t h e s am e pr e p ar a t io n an d abo u t ,

t h e y e ar 1 8 74 t h e eli xi r m a n i a w as at i t s h e igh t T he .

b u rde n t h u s t hro w n u p o n o u r ph ar m ac i s t s w as c o ns id e r
abl e — m ore i n t h e ag g r eg ate t h an m o s t O f u s can r e ali z e .

The fi r st pu bl i sh ed fo rm ul a t h at I c an fi n d fo r an y o f t h i s c l ass o f p rep

arat i o n s un d er t h e nam e El i x i r i s t h e fo r m u l a w e i v e fo r El i x i r o f C al i saya
g
. . J
b y M r A l fred B T ayl o r , fro m t h e o u rn al o f P h ar macy, an u ary, 1 8 59 J .

T he D ruggi s t s C i rc u l ar o f sam e d at e st ate s that u p to t h at t i me no fo r

’

m ul a fo r t h at p repar ati on h ad been pu bl i shed .

 3 EL1 x 1 RS .

a b rie f sy nop s i s o f t h e h i s t or y o f t h e cl ass o f p h arm ace u

t i c al s u n der c o n s id er at io n an d doe s n o t w i s h t o arg u e
,

i n fav or or ag ai n st t he m ; an d t h e e lixi r o f t h e pr e se n t
d ay h as b e e n re ached .

Th ro u gho u t t hi s c o u nt ry t h e prep ar at i o n o f e lixi r s h as

g e n e r all y p asse d fro m a fe w w hol e s al e m an u fac t u re r s
i n t o t h e h an d s o f t h e m any ph ar m ac i s t s Q u a n t i t i es
. o f
e li x i r s are pre s c rib e d b u t t h e i r prep ar at io n h as e x t e n d e d
,

o v e r th e e n t i r e c o u n t r y i n s t e ad o f b e i ng c o n fi n e d to a
fe w lo cali t ie s . Ph y s i c i an s h av e t hei r fav ori te e l ixir s an d
pr esc ri b e t h e m b u t t h e se e lixi r s m u s t as a r u l e b e n u
, , ,

q u e st io n abl e . I n m a n y i n s t an c e s ho w ev er i n c o m p at i
, ,

bl e s are u n do u b t edl y bro u gh t t og e t h e r at t h e expe n se o f

t h e p rod u c t d r u g s i n s ol u bl e i n t h e m e n s t r u u m a re s u p
,

p o s ed t o b e re p r e s e n t e d b y t h e r e s u l t an t e li x i r an d t e ,

d io n s ro u nd abo u t m e t hod s are e m plo y e d w h e re s i m pl e

, ,

d ire c t pro c e s ses c an b e s u b s t i t u te d B e for e c o nsi d e ri n g

.

elixi r s i n d i v id u all y i t i s b u t j u s t t o r e v i e w t h e i r hi s t ory

,

d u ri n g t h e p ast t w e n t y y e ar s fo r m an y ph ar m ac i st s h av e
,

n o t t h e n e ce s s ar y w ork s at t h e ir c o m m an d a n d r e fe r e n ce ,

i s c o n s t an t l y m ade t o t h e ac t io n o f t h e s o c i e t i e s w h i c h
c o n s ider e d t h e m a n d t h e m e n w h o e arl y m ad e t he m a

st u d y .

The C o m m i tt e e o n U n o ffi c i n al Pr e p ar at io n s appoi n t e d
b y t h e A m e ri c an P h a r m ac e u t i c al A ss o c i a t io n i n 1 8 70 , ,

w as Pro fe ss or J F ari s M o o r e M D
. w h o i nc l u d e d i n
, . .
,

h i s repor t t o t h e S o c i e t y ( 1 8 7 1 ) a se ri e s o f e li x ir s a n d ,

t hi s w as t h e fi r s t g e n er al r e c og n i t i o n t he s e pr e p ar at io n s

re cei v ed fro m t h at bod y I n th e y e ar foll o w i n g th e ap

.

poi n t m e n t o f t h e c o m m i t t e e M r O t t m ar Eb e r .

b ach re ad a v ol u n t e e r p ap e r b e fo re t h e S o c i e ty at i ts
m e e t i n g i n C l e v e l a n d O hi o i n w h i ch he g av e t h e re
, ,

s u l t o f h i s an al y s i s o f se v e r al c o m m e r c i al e lixi r s The .
 E LI X I R S . 19

p aper pro v oked c o nsid e r abl e d i sc u ss i o n , an d r esu l t e d in

t h e follo w i n g

Resol v ed , T h at a c o m m i t t ee o f fiv e be ap p oi n t ed b y th e P r es i
d e n t , t o t ak e i n to c o n s i d e r at i o n j
t h e s u b e c t o f el i x i rs and si m i l ar
u no ffi c i n a l a at i o n s in al l i t s b e ar i n g s n h ar m ac , a nd ,
p re
p r u
p o p y
i f d e e m e d p ro p er , t o re p or t s ui t ab l e fo rm u l as fo r t h e gu i d an c e of

t h e m em b e r s o f t h i s A ssoc i a t i on .

In Pro fe sso r C L e w i s D i eh l c o nt rib u ted an i n te r

1 8 72 .

e s t i n g p aper o n t h e elixi r s u bj ec t I t w as r e ad b e for e .

t h e L o u i sv i ll e C oll ege Of P h a r m acy an d aft e r w ard p u b ,

l i sh e d b y t h e ph ar m ac e u t i c al j o u r n al s an d b y t hi s m e an s ,

s e v er a l ad m i r able for m u l a w e r e i n t rod uc e d M an y o f .

t he se pro c ess e s are s t il l u s e d a n d ac c e p t ed as s t an d ard ,

bei n g pre ferred b y ph ar m ac i s t s t o t ho se aft er w ard o f

fe r e d as i m p ro v e m e n t s Nex t th e c o m m i tt e e
.

appoi n t e d b y t h e A m e ri c an Ph ar m ac e u t i c al A ss o c i at io n

m ad e a m i n ori t y repor t ( i n c l u di n g m any for m u l a ) w h i c h ,

w as th at o f t h e c h ai r m an o f t h e c o m m i tt e e M r J F , . . .

H an co ck an d w h i ch aft e r s o m e d i s c u s s i o n w as adop te d
, , , ,

an d t h e follo w i n g r e s ol u t io n s w e r e o ffe r e d b y Pro fe s s or

J .M M a.i s c h :

R esol v ed , T h at th e repo r t be a d o p t ed ,
w i th th e rec o m m en d a

t i o n t h at t h e s e fo rm u l as b e u se d b y t h e m e m b ers o f th e As s o c i a
t i o n , a nd t h a t t h e S ec re t ar y b e i n s t r u c t ed t o se nd a p r i n t e d Co
py
w i th th e r e p o rt to th e m ed i c al so c i e t i e s o f th e U n i t e d S t at e s , w i th
th e s u gges t i o n t h at
h
p y s i c i a n s ,
i f p r e s c r i b i n g e l i x i r s a t a l l , p
r e

s c ri b e o n l y s u c h fo rm u l as as h a v e b e e n ad o t ed b
p y t h s A s soc i a i
t i on . l
T h e o bj ec t i s t o a ttai n , as n ear y as p o ss i b l e , a u n i fo rm i t y
in th e U n i te d S tat es .

Resol v ed , T h at M r .
J . F H an co c k b e ap p o n t ed i th e C om mi t
t ee on U n o ffi c i nal F orm ul as .

A t th e m ee t i ng of th e S o c i e t v w h i c h fo l lo w ed i n Lo u
i sv i l l e K y , .
, 1 8 74 , t h e C o m m i t t ee on U no ffi c i n al F o rm u
 E LI X I R S .

i n t rod u ce eli xi r s H o w e v er M r Ebert o f

l as fai l e d t o .
, .
,

C hi c ago pr e se n t e d a s e ri e s o f e lixi r for m u l a b as e d u po n

, ,

t ho s e o f Pr o fe s s or C L e w i s D i e hl an d pr e p ar e d b y a
.
,

c o mm i tt e e u n d e r t h e s u p e r v i s io n o f t h e C h i c ago C oll e g e

o f Ph ar m ac y an d s u g g e st e d
, t h at t he y b e r e v i s e d o r
adop t e d b y t h e S o c i e t y fo r e n er a l A ft er a n an i
g u s e .

m at e d d i sc uss i o n M r P e i x o t t o O ffer e d a re s ol u t io n
, .
,

w h i c h am e n d e d b y M r Rob e r t s w as adop t e d as fo l
, .
, ,

lo w s

R esol v ed , T h at a co mm i t t ee o f t h r ee be ap p o i n ted , t o w h om

s h al l b e r e ferre d th e fo r m u l as of e l i xi rs
p r e s e n t e d b y th e C h i c ago
C o l l ege of Ph arm ac y , s ai d co m m i t t ee t o e x am i n e t h e fo rm u l as an d
c ar e fu l l y c o m p ar e t h e m w i th t h e form ul as ad o p t ed a t t h e l as t an

n ua l m ee t i ng , or wh i ch m ay b e s u b m i tt ed t o th e m , t o m odi fy an y

or all fo rm ul as i f n ece ss ar y , an d to r e o rt to t h e n e x t
p m eeti ng .

A t the ex t m ee t i ng 1 8 75 t h e c o m m i ttee repor t ed a

n , ,

n u m ber o f for m u l a s o m e d i fferi n g fro m t ho s e pre v i

,

o u s l y adop t ed b y t h e S o c i e ty o t h e r s ne w S i nc e t h at
, .

t i m e m any for m u l a h av e b e e n i n t rod u c e d t hro u gh t h e

Re por t o n t h e Progr e ss o f Ph ar m ac y w h i ch i s t he
”

por t io n o f th e Pro ce e d i ng s o f t h e A m e ri can P h ar m ac e u

t i c al A ss o c i at io n de v o t e d t o a r e v i e w O f t h e ad v an c e O f

ph arm acy d u ri ng t h e y e ar b u t t h er e h as b ee n n o o t he r
,

O ffi c i al c o ns id e r at io n o f t h e s e pr e p ar at i o n s .

I n re v i e w i n g t h e w ork t o w h i c h w e h av e r e fe rred w e ,

S h all s i m p l a t h at i m a i t e xp ri h a
y s
y n n y n s a n c s e e e n c e s

d e m o n st r at ed t h at t h ere are de fe c ts i n t h e for m u l a w h i c h

m ay be o v er c o m e I t w as n o t t o be e xp e c t e d t h at t h e
.

w ork o f t he se c o m m i tt e e s c o u ld b e p e r fe c t a n d w h ile ,

fro m n e ce s s i t y w e o ft e n d ev i at e i n m an i p u l at i o n fro m t h e
‘

for m u l a o ffer e d b y t h e c o m m i t t e e s w e fe e l t h at i n as ,

m u ch as t h e p r opor t i o ns o f t h e m ed i c i nal i n gred ie nt s are

 EL I X I R S . 2I

r e t ai ned by us, o ur for m u l a m ay be co n s i d e red as an

s w e ri n g the re q u i re m e n t s o f t h e A m eri c an P h ar m ace u t i
c al A ss o c i at i o n T w el v e ele v e n an d eigh t y e ar s h av e
.
, ,

p assed s i n c e t he s e c o m m i t t ees s u cce ss i v e l y repor t ed ,

m or e t h an t h e t i m e r e q u ir e d b e t w ee n re v i s i o n s o f o u r
Ph ar m ac op oei a an d d o u b t le ss t h e m e m ber s o f t h e c o m
,

m i tt e e h a v e i nd i v id u all y re v i s ed m an y o f t h e i r pro
c e s s e s p ro fi t i n g b t he a r s o f e xperi e n c e an d b t h
, y se
y e
y e

c ri t i c i s m s o f o t h e r s I n c o nn e c t io n w i t h t h e e l ixi r q u e s:
.

t io n an d t h e A m e ri c a n Ph ar m ace u t i c al A ss o c i at io n w e ,

m u st n o t o v e rlook t h e v al u abl e p aper pr e se n t ed b y M r .

R W G ard n e r at t h e m ee t i n g i n S ar at o g a 1 8 80 an d
. .
, ,

w h i ch e m br ac e s m ore for m u l a t h an h ad el se w here t o ,

o u r k no w l ed e
g be ,
e n c o m pi led at t h at t i m e a n d t o ,

w hi c h w e o ft e n r e fe r i n t h e w ork w hi c h follo w s We .

m u s t n o t o v e rlook t h e s e rie s o f for m u l a adop t e d by t h e

N e w ark Ph ar m ac e u t i c al A ss o c i at io n 1 8 76 an d t ho s e , ,

a dop t ed b y t h e A s s o c i at e d C o m m i t t e e s o f t h e Na
t i o n al C oll e g e o f P h ar m ac y an d t h e M e d i c al S o c i e ty o f
t h e D i st ri c t o f C ol u m bi a . Th e for m u l a re c o m m e n d e d
b y bo t h o f t h e s e bod ie s w e re p u b l i sh e d i n t h e v ari o u s
ph ar m ac e u t i c al j o u r nal s an d s e r v ed a good p u rpo se .

C o m po u n d e li x i r s h av e n o w m u l t i p lied u n t i l t h e i r
n u m b e r i s s u c h as t o be b u rd e n s o m e The proble m
.

reg ard i n g propor t io n o f i ngred ie nt s w as o n e t h at e arl y

c o mm an ded o u r at t e n t i o n an d w h i c h w e e n de av ored t o
,

s y st e m at iz e i n t h e ab s e n c e o f au t hori ty s o as t o co n
, .

for m i f po ss ible t o s o m e g e ner al r u l e The n e c e s s i ty fo r

, , .

s o m e s u c h ac t i o n m ay b e ill u s t r at e d as follo w s

Elixi r o f pho s ph at e o f q u i n i n e c o n tai ns o n e gr ai n o f

q u i n i n e i n e ac h fl u i d d r ach m .

Eli x i r o f p e p h o s p h at e o f i ro n c o n tai n s t w o gr ai ns
of h h at f i ro n i n e a h fl i d d r a h m
pe p o s
p e O c u c .
 EL l kS .

Wh at sh all be t h e propor t io n o f pho s p h ate o f q u i n i n e

a n d o f p y ropho s ph at e o f i ro n i n e ach fl u id d r ach m o f

elixi r o f pho sph at e o f q u i n i n e a n d p e p h o sp h at e o f

i ro n " A g ai n ,

Elixi r o f pho sph at e o f q u i n i ne c o n tai n s o n e gr a i n o f

q u i ni n e i n e ac h fl u i d d r ach m .

Elixi r o f pho s p h at e o f c i n ch o n idi ne c o n tai n s o n e

gr ai n o f c i nc ho n i di ne i n e ach fl u id d r ach m .

Elixi r o f pho s ph at e o f c i n c ho n i ne c o n t ai n s t w o gr ai n s
o f c i n c ho n i n e i n e ac h fl u id d r ac h m .

Wh at sh all b e t h e p ropor t io n o f t h e s e v e r al i n gr e
d i e n t s i n t h e e l ixi r o f pho s ph at e o f q u i n i n e c i n cho n i di n e
, ,

a n d c i n c ho n i n e "

I f e ac h fl u id d r ach m o f t h i s l as t el ixi r c o n t a i n s t h e
a m o u n t o f e ac h i n gr e d i e n t w hi c h i s pr e se n t i n t h e s am e

a m o u n t o f t h e s i m pl e e l ixi r o f t h at s u b s t a n ce w e w i ll ,

h av e fo u r gr ai ns o f t h e c o m b i n e d alk aloid s a n u n re a ,

s o n abl e q u an t i t y fo r a p r e p ar at io n o f t h e ch ar ac t er o f an

elixi r .

I n c o n s eq u e n c e o f ex am pl e s s i m i l ar t o t ho se abo v e
n am ed an d w hi c h d e m an d e d s o m e r e g u l ar pl an o f
p ro ce d u r e i f s u c h c o u ld b e d e v i se d w e h av e fo r m any
, ,

y e a r s a t t e m p t e d t o s y s t e m at i z e t h e m at t e r an d o u r e ffor t s
,

h av e m e t w i t h s o m e s u cc e ss . I n m aki n g c o m po u n d
elixi r s w h e r e i t w as po ss ibl e w e h av e r e pr e se n t e d i n
, ,

e ac h fl u id d r ac h m t h e ag g r e g at e a m o u n t o f alk aloid s

w h i c h w o u ld b e p r e se n t w e r e t h e se v e r al e lixi r s m ix e d
t og e t h e r i n e q u al q u an t i t i e s. W e b e l i e v e t h at as a r u l e
, ,

u n der t h e c o n d i t io n s w h i c h c o n fro n t u s i n t h e probl e m

o f c o m po u n d e lixi r s ph y s i c i an s d e s i r e t h e ass o c i at e d
,

ac t io n o f s m all e r am o u n t s o f t h e s e v e r al i n r e di e n t s
g
r at h e r t h an t h e fu ll do se o f e ach I t i s t r u e th at fo r o b
. .

v i o us re aso n s t hi s r u le c ann o t al w a s be u pheld b t

,
y u ,
 EL I X I R S . 23

w h e r e i t h as b e e n pr ac t i c abl e we h av e en de av or e d to

ca rr y it out .

Th e propo rt io n o f s t r y c h n i n e i n th e e l ixirs o f c o m
m e r c e h as n e v e r b e e n u n i for m an d e v e n t h e m e n w h o ,

s e e m t o h av e m ad e e lixi r for m u l a a s p e c i a l c o n s ider a

t io n v ar y o n e fro m an o t h e r S o m e u s e o n e gr ai n o f
.

s t r y c h n i n e t o s ix t e e n fl u id o u n ce s o f the fi n i shed e lixi r ,

w hi c h i s t h e o n e h u n d r e d and t w e n t y e igh t h p ar t o f a
- - -

gr ai n t o e ac h fl u id d r ac h m w hil e o ther s u s e se v e r
‘

all y o n e h u n dr e d t h
-
o n e s ix t i e t h
,
an d-
o n e fi ft
y fi rs t o f ,
- -

a gr ai n S t r y c h n i n e i s far t o o v iol e n t an d poi s o n o u s

.

a s u b s t a n c e fo r s u c h a r an ge o f p ropor t io n s an d i n o u r ,

opi n i o n i t i s t o b e regre t te d t h at e v e n t ho u gh ig n ori n g ,

e l ixi r s as a c l as s o u r C o m m i tt e e u po n Re v i s io n o f t h e
,

Ph ar m ac op oe i a d i d n o t adop t so m e propor t io n w h i c h
p h a r m ac i s t s c o u ld adop t i n order t o fu r t he r a u n i for m i t y

i n t he s e p r e p ar at io n s I n o u r w ork w e h av e ac ce p t e d
.

t h e repor t l as t adop t ed b y t h e A m e ri c an Ph arm ac e u t i

c al A sso c i at io n o u elixir s an d o u r s t an d ard i s t w o a nd
,

o n e h al f gr ai n s o f s t r y c h n i n e t o s ix tee n fl u id o u n c e s o f
-

t h e fi n i shed e lixi r w h i c h i s e q u i v ale n t t o o n e fi ft y fl rst

,
- -

o f a gr ai n i n e ac h fl u i d dr ac h m Thi s w e c o n s i de r n e ar
.

e n o u gh t o be called i n ro u n d n u m ber s on e fif t i et h o f a
, ,
-

g r a i n a ,
n d a s w e h av e n o t d e v i at e d fro m t hi s p ropor t io n

i n t h e w ork w hi c h follo w s w h e r e v er w e u se t h e e xpr e s

,

s io n o n e fi ft i e t h o f a gr ai n
-
t h e for e goi n g propor t io n
,

i s u n der st ood .

I n m aki n g s ol u t i o n s o f st ry c h n i n e w e c o n v e r t i t i n t o ,

a s ol u ble s al t b y m e an s o f ace t i c ac id Thi s for m s a .

c o m bi n at io n w h i ch i n o u r e xp e ri e n ce i s b es t fo r as s o

c i at i n g s t r y c h n i n e w i t h t h e e n t i r e li s t o f s u b st an ces
w hi ch are u sed t o for m t h e c o m po u n d eli xi r s c o n t ai n i n g
t h at alk aloi d I n s o m e i n s t anc e s t h e elixi r i n w h i ch th e
.
24 ELI X I RS .

st ry ch n i ne i s to be pl aced h as an alk al i ne re ac t i o n and

m ay de c o m po s e t h e sal t y e t as t h e e lixi r c o n t a i n s s o m e
,

al c o h ol an d b e s ide s h as as a m e n s t r u u m a s ol v e n t ac t io n
,

di ffe r e n t fro m t h at o f w at e r i t doe s n o t n ec e ss aril y fo l

,

l o w t h at pre c ipi t at io n o f t h e alk aloid w ill re s u l t Ho w .

ev er ,
i t i s w el l t o be cau t io u s and s ho u ld a w hi t e fl o c c u
,

l e n t p r e c ipi t at e occ u r i n e li x i rs c o n tai n i n g st ry c h n i n e

an d w h i c h are alk al i ne i n r e ac ti o n t h i s p r e c ipi t at e
,

s ho u ld be c o n s ide red as d ange ro u s a n d care e xer c i s e d

i n d i s p e n s i n g th e elixi r .

I n al l t h e for m u l a w h e r e i t i s pr ac t i c able w e h av e i n
t r o d u c e d fl u id e x t r ac t s i n s t e ad o f c r u d e d r u g s Thi s w e
.

c o n s ide r ad v an t ageo u s fo r s e v e r al r e as o n s an d fl u id ex
,

t r ac t s m ay n o w b e re ad il y ob t ai n ed t o repr e se n t n e arl y

e v er y pl an t u sed i n m e di c i n e I n m an y i ns t an ces w e
.

obj ec t t o ce r t ai n d r u g s u n de r any c o n s id e r at io n as t h e
fo u n d at i o n o f an e lixi r an d w e h av e n o t he s i t ated t o
,

c ri t i c i s e fr ee l y w h e re t h e m ed i c i n al pri n c ipl es o f t h e
d r u g c an n o t i n o u r O pi ni o n b e e x t r ac t e d or h e ld i n sol u
t io n by t h e e lixir . H o w ev e r i f t h e m e n s t r u u m p r e c i p i
,

t ate s t he s e pri n ciple s fro m t h e fl u id e x t r ac t i t w ill prob ,

abl y re fu s e t o ex t r ac t t h e m fro m t h e c r u d e dr u g s o t h at ,

li tt le i f any ad v an t ag e w ill acc r u e i n t h i s d i re c t io n fro m

t h e u se o f t h e c r u d e m a t e ri al We v ar y fro m t h e m e t h
.

o d s e m plo y ed b y t h e c o mm i t t ee a ppoi n t e d b y t h e A m er

i c an Ph ar m ace u t i c al A sso c i at io n r e g ard i n g t h e m an n e r

o f m ixi n g a t i n c t u r e or fl u i d ex t rac t w i t h t h e m e n s t r u u m .

I f t h e y are m ix e d d i re c t l y t og e t her pr e c ipi t at io n r es u l t s

.

i m m e di ate l y o f m uch o f s u c h s u b t a nc es as are i n s ol u bl e

s

i n t h e r e s u l t an t m e n s t r u u m l h i s p r o d u c e s a pr e p ar a
'

t io n w h i c h ph a r m ac i s t s an d ph y s i c i an s r e fu s e t o a c c e p t
as an e lixi r . Tr u e i t i s t h at t h e se s u b st anc es m av b e
i ner t an d t h at fil t r at io n w ill sep ar at e t he m ; y e t t h e n a
,
 26 ELI X I R S .

fi l l th e hel v e s o f an ordi nar y st ore roo m The proble m

s -
.

t o be c o n s id e r e d b y ph ar m ac i s t s i s t h at o f fi n d i n g t h e
mo st c o nv e n i e nt m e th od w hi c h w ill e n able t h e m t o d i s
p e n se t he se c o m bi n at io ns i n a c red i tabl e m an n e r w i t ho u t
o v e r st o c ki n g t h e i r s h e l v es Thi s h as b ee n an d i s a c o n
.

s ider at io n o f pr ess i n g i m por t a n c e t o t h e w ri t e r an d t h e ,

t ro u bl e h as b e e n o v er c o m e t o a v e r y gre at e x t e n t b y
, ,

adop t i n g a s y s t e m w hi c h w o u ld p e r m i t t h e pr e p ar a t io n o f

c o m po u n d e lixi r s fro m t ho s e m or e s i m pl e a n d i n s t u d y ,

i n g h o w t o m ak e t h e d i ffer e n t e lix i r s fr o m c o m p at i bl e
’

i n gr e d ie n t s I n m an y i nst an ce s t h i s i s i m po ss ible w i t ho u t
.

i nj u ry t o t h e p rod u c t a n d y et i n t h e l arg e majori t y o f

, ,

c as e s ph ar m ac i s t s are abl e t o e x t e m pori z e an d s u ppl y

,

m o s t d e m an d s fro m t h e i r s t o ck o f s t an d ard e li x i r s w hi c h ,

ar e t ho s e i n m o s t c o m m o n u se .

S o m e e lixir s m ay be c all e d per m an e n t b u t t h i s t e r m ,

c an n o t b e appli e d t o t h e l a r e r n u m b e r A s s o c i at io n s
,

g .

o f t h e alk aloi d s i n ac id s ol u t io n o n l y o r e l ixi r o f p y ro

,

pho sph at e o f i ro n i n alk ali ne s ol u t io n or o t h e r s u n d e r ,

c er t ai n c o n d i t io n s m ig ht po s s i b l y b e c l ai m e d as fai rl y
,

p er m a n e nt . H o w e ver ,
t h e e lixi r o f p y ropho s ph at e o f

i ro n w ill d ec o m po s e i f expo s e d t o t h e s u n ligh t o r e v e n

s t ro n gl y di ffu se d d ay ligh t a n d i t m ay gel at i n i z e aft e r a
,

t i m e i f o f ac i d re ac t io n w h i l e al t e r at io n s w i l l follo w w i t h
,

t h e s ol u t io n s o f t h e alk al o id s F e w o rg an i c bod ie s a re
.

per m an e n t i n s ol u t io n c o n ta i n i n g far m o r e al c o hol th an

i s p e r m i ss ibl e w i t h t h e m od e r n e l ixi r a n d i n c o n s e q u e n c e
,

m an y el ixi r s w ill al t e r i n app e ar a n c e o r e v e n p r e c ipi t at e

, ,

i f t h e y c o n t ai n t h e s u b s t an c e s w hi c h a re s u ppo se d t o be
p re s e n t .

I n r ev ie w i n g t h e for m u l a w h i c h follo w t h e r e ad e r ,

m ay c ri t i c i s e t h e n u m b e r o f d i ffe re n t e l i xi r s p r e s e n t e d .

Thi s w e ad m i t i s a fau l t b u t o ne be y o n d o u r c o n t rol

, , , ,
 ELI X I R S . 27

an d s o m e o f t h e e l ixi r s are seldo m u sed so m e are s i m ,

l e c u rio s i t i e s Thi s c o u n t r y i s l arg e ho w e v er a d i f

p .
, n ,

t h e r e ad e r w i ll reg ard a c er t ai n pr e p ar at i o n as o n e w h i c h

s h o u ld h av e bee n o m i t t e d he m ay be s u rpri s e d t o le ar n
,

t h at i n o t h e r lo c ali t ie s i t i s v e r y m u c h i n d e m an d Ti m e
.

an d ag ai n w e h av e bee n s u rpri s e d o n l e ar n i n g o f t he lo c al

c o n s u m p t io n o f s u b s t an ce s w e s c ar ce l y t ho u g h t c o m

m an d e d a s al e an d u po n t h e o t h e r h an d w e h av e ex
, ,

c i t ed c o m m e n t o v e r c e r t ai n prep ar at io n s s c ar c e l y k n o w n

t o o t h e r s a n d y e t m ade b y u s i n q u an t i t i e s I n co nnec
.

t i o n w i t h t h i s ph as e o f t h e s u bj e c t w e fee l t h at o u r
po s i t i o n i s n o t t h at o f j u g
a d e — a po s i t io n o c c u pi e d b y

c re t a —
i n co m i t t e e s b u t t h at as o u r s u bj e ct i s e lixi r s
m , ,

i t i s o u r d u t y t o c o n s id e r t h e m as a bod y .

We d es i re t o c all at t e n t io n t o t h e fac t t h at i t w as o u r
fi r st i n t e n t i o n t o gi v e t h e s e v e r al p r o ce sse s an d c r i t i
c i s m s w hi c h h av e b e e n m ade reg a rdi n g e ac h e lixi r i n t ro

d u ce d d u ri n g t h e p ast t w e n t y y e ar s Th i s p ro v e d to
.

be i m pr ac t i c abl e an d w e w e r e fo fc e d t o d r aw t h e li n e
,

s h a rpl y. I f t h e re ader w i l l se l e c t as an e x am ple an y

o n e o f t h e p ro m i n e n t elixi r s an d h u n t u p t h e r e v i e w s
, ,

d i ffere n t for m u l as et c r e g ard i n g i t w h i c h h av e ap

,

e are d i n t h e v ario u s ph ar m a c e u t i c al j o u r n al s an d t h e
p
Pro c e e d i ng s o f t he A m e ri c an P h ar m ac e u t i cal A ss o c i at ion
d u ri n g t h at p e riod he w ill do u b t l e ss b e as t o n i sh e d at t h e
,

m ag n i t u d e o f th e m at t e r ; an d w h e n i t i s r e m e m ber e d
t h at r e c e n t y e ar s h av e gi v e n u s s e v e r a l n e w an d w or t h y
ph ar m ac e u t i c al j o u r n al s and t h at e lixi r s are m or e o r
,

l ess c o n sid e r e d b y al l o f t h e m i t w ill be see n t h at t o

,

gi v e an i n t e ll ig e n t an d fai th fu l r cs u m e i n a w o rk li k e
’ ’

o u r s w o u l d b e i m pr ac t i c ab l e .

O u r ai m h as b e e n t o c r e d i t t h o se w h o i n t rod u c e d sp e
c i al c o m bi n at i o n s an d t h e j o u r n al s w ho s e p ag e s w e co n ~
28 ELI X I RS .

su l te d to fi n d t hei r r ec ord s ,
an d if e r s igh t s h av e bee n
ov

m ade ,
as is l i kely , w e as s u re th e re ader t h at t he y w ere
i e n t i o n al
u n nt .

I n c o n c l u s io n w e m ay s ay t h at w e t r u s t ph ar m ac i s t s
,

w ill fi n d o u r for m u l a t o pre s e n t s o m e ad v an t ag e s o v e r

a li n e o f c o m pi l at io n s fo r t h e y are n o t s i m pl y ab st r ac ts
,

fro m th e w ork t h at o t her s h av e do n e .

 ELIX I R F O R M U LZE .

EL IXI R A D JUV AN S .

F l u i d E x t ra c t O ran g e P e el 54 flu i d ou n c e s

F l u i d Ex t ra c t C ori a n d e r .

F l u i d E x t ra c t C a raw ay
F l u i d E x t ra c t W i l d C h e r ry B a rk x

F l u i d E x t ra c t L i q u ori c e R oot
S i m pl e El i x i r
A l c oh ol
C a rb on at e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Mix fl u id ex t rac t s an d e v aporat e t he m t o o ne

the
h al f t heir b u lk at a t e m p e rat u re n o t e x c eedi n g 1 50 F ah
°
.
,

Tri t u r at e t h e r e m ai n i ng liq u id i n a cap ac io u s m o rtar w i t h

'

carbo n at e o f m ag n e s i u m i n am o u n t s u ffi c ie n t t o for m a
,

cr e am y m ix t u re t h e n grad u all y add t h e s i m ple elixir

’

, ,

s t irri n g w ell an d fi l t e r
,
L as t l y m i x t h e fi l t rat e w i th t h e
.
,

al c ohol . The i ngr e die n t s fo r t hi s elixir w ere nam ed i n

th e D m gg zlsts Ci r cu l ar
’
1 87
‘

, 9 .

ELIXI R O F B RO M I D E O F A M M O N I U M .

B rom i d e of A m m on i u m 6 4 0 g ra i n s
S i m pl e El i x i r

D i ss ol v e bro m ide o f am m o n i u m i n t h e s i m ple

th e
elixir an d fil t er i f n e c essar y
, .

Eac h t eas poo n fu l o f t h e fi n i shed el i x ir co nt ai ns fi v e

g r ai n s o f br o m id e o f am m o n i u m .
 EL I X IR F O R M U LJE .

E L IXI R A L O ES .

( CO M UND
PO T xN C r U RE O F
'

A L E O S. )
t roy ou n c es

3
T i n c t u re M y r rh . a p i n t s

Re d u c e t h e
dr u gs t o a c o arse po w der and m acerat e i n
th e al cohol fo r fo u r t ee n d ay s st irri n g t h e m ix t u re t h or ,

o u ghl y e ach d ay fil t e r .

I“
T h e N ew D i s p e n sa t o r y , Lon d on , I 77°

EL I XI R O F V A L E R I A N A T E O F A M M O N I U M .

V al e r i an a t e of A m m on i u m 2 56 g rai n s
S i m p l e E l i x i r, A m m on i a - W at er , C a rm i n e "
S ol u t i on , of

e a c h a s u ffi c i e n t q u a n t i ty .

D i ssol v e t h e l ri anate o f am m o n i u m i n t w e l v e fl u id
va e

o u n ces o f s i m ple elixir an d bri ng t hi s t o th e m e as u re o f ,

s ix t e e n fl u id o u n c e s b y t h e addi t io n o f a s u ffi c i e n t am o u n t

o f s i m ple el ixi r The n cau t io u s l y ad d am m o n i a w at er

.

u n t il i n s ligh t e x ce ss an d color w i t h s ol u t io n o f car m i n e

,

u n t il de c idedl y re d Eac h fl u id drac h m t e aspoo n fu l ) o f

.

t h e fi n i s hed elixi r repre se n t s t w o gr ai n s o f va l e ri anat e o f

1
‘‘
SO L U T 10 N o r C A R M I E N i p p
T h s r e ar at i o n h as b e e n u s e d som e t w e l v e y e ar s by
p f
.

t h e w ri t er , i n i h i l T h e fa t i n c o c h i n e al c au s e s
"
r e e r e n c e t o an
y t n c t u r e o f c o c n e a
p p p f
.

su ch r e ar a t i o n s t o u t r e y i n w ar m w e at h e r ; an d t o e x t r a c t t h e fa t b y m e an s o f
'

f
et h er rom t h e po w d e r e d c o c h i n eal p
r ev i o u s t o t i nct u r i n i s e x e n si v e a n d t ed i ou s g p .

pp p pp q
, ,
“
T h e te r m t i n c t u r e o f c oc h i n e al
”
i s s c ar c e l y a ro r i at e as a l i ed to t h e a u eo u s
i p
,

so l u t o n s m a d e o f c oc h i n e al c r eam o f t a r t a r a n d al u m a n d as t h e o b i e c t i s s i m l y
g g q p p pp
, ,

t o s e c u re a co l o r i n m a t t e r t h e t e r m mi h t w i t h e u a l r o r i e t y b e a li e d t o o u r so
l u t i o n o f c ar m i n e, mad e as o l l ow s : f
,

C ar m i n e , N o 40 ,
. 60 g i
ra n s

W
D i s t i l l ed at e r , Gly c e r i n , o f e ac h , 4 fl uid o u n c es

A m m on a i W at e r , a su ffi c xe n t q u an t t y .i
.

P o w d e r t h e car m i n e an d t r i t u rat e w i t h t h e w at er r ad u all y ad d i n amm o n i a g g

pp k q f f
,

w at e r , u n t i l t h e c ar m i n e d i s a ear s a n d a d ar re d l i u i d re e r o m i n s o l u b l e m a t t e r ,
g i
,

r e m ai n s T o t h i s ad d t h e l y c e r i n e , an d mi x Sh o u ld t hi s s ol u t o n e v e r b e c o m e
k p
. .

m u r y a l i t t l e am m o n i a w at e r w i ll r e s t o r e i t s t ran s ar e n c y
k p
.
,

S o l u t i o n o f c ar m i n e i s n e c e s s ar i l y al al i n e , an d c an n o t b e e m l oy e d t o col o r ac i d
q
li uid s k
F o r all n e u t ra l o r al al i n e sol u t i o n s i t i s ad mi r abl e , an d fo r so d a w at e r s y r u s p
p f
.

i s far r e e r abl e t o an ali n e r ed .

 E LI XI R F O R M U L/E .
3 I

am m o n i u m t h e sam e as t h at adop ted by t h e A m eri can

,

Ph ar m ace u t i cal A sso c i at io n 1 8 73 ,

.

V al e ri anat e o f am m o n i u m e spe c i all y i f th e v aleri an i c ,

ac id i s i n ex ce s s h as t o m o s t per s o n s a v ery o ffe n s i v e

, , ,

Odor . Thi s t h e addi t io n o f t h e amm o n i a w at er t e n d s t o

s u bd u e ,
b u t w here v er v aleri anat e o f am m o n i u m i s fre e ,

or i n aq u eo u s sol u t io n t h e odor w ill re m ai n I f di ssol v ed

,
.

i n o ffi ci nal al c ohol ho w e v e r i t i s scar cel y app are n t b u t

, , ,

s u c h a s ol u t i o n w i ll n o t co n for m t o o n ; m oder n e lixir

”
.

The addi t io n o f w at e r t o th e al coholi c sol u t io n re v i v e s t h e

odo n
Th e h i st or y o f t hi s elixir i s o f i n t ere st s i n ce i t w as ,

am o n g t h e fi r s t o f t h e pop u l ar e lixir s i n t rod u c e d an d h as ,

re tai n ed i t s pre st ige t o th e pr esent d ay I n an essay by .

M r T ro v i ll o H K E n o s re ad be fore t h e M ary l an d C o l
. . .
,

lege o f Ph ar m acy 1 8 6 1 th e stat e m e n t i s m ade t h at a

, ,

prep arat io n k n o w n as Pi erl o t s s ol u t io n o f V aleri anat e o f ’

A m m o n i u m h as lo ng b e e n u sed am o n g ph y s i c i an s i n Phil
adelphi a ; b u t t h e di sagree able tas t e an d odor o f t h e s ol u

t io n h av i n g be e n fo u n d obj e ct io n abl e t o p at ie n t s th e ,

ph ar m ac i st s h av e bee n led t o s u gge st s o m e m ode o f d i s

g u i s i n g bo t h an d pre
,
s e n t i n g t h e prep ar at io n i n an a gree
able for m fo r ad m i n i s t r at io n w i t ho u t m at eri all y al t eri n g
,

i t s e ffe ct ; an d t h e for m o f an elixir h as bee n adop t ed .

M r E n o s t he n gav e h i s for m u l a w hi ch w as as follo w s :

.
,

V al er i an i c A c i d I fl u i d d rach m
S i m p l e Sy r u p 1 fl ui d o u n ce

Ex tr ac t o f S w eet O range Peel 2 fl u i d d r ach m s

A l co h o l 1 fl uid ou n ce

O ran ge F l o w er w ater fl ui d n ce
o u-

D i sti l l ed w ate r, C ar b o n ate of A m m on i u m , of

each a s u ffi ci en t q u an t i ty .

D il u te th e i
v al er an i c ac i d w i th o n e-h al f fl ui d o u n ce of w ater , an d
n eu tral i z e i t w i th t h e car b on ate o f am m o n i u m , ad d th e al coh ol , h av i ng
3 2 EL I X IR F O R M U LA-
3 .

p re v i o u sl
y m i x e d i t w i th th e fl u id e x t rac t o f o r an
g
e
p ee l , an d th en add

t h eo th e r i n g red i e n t s, an d fi l t er .

I n t h e y e ar 1 8 6 3 M r j o s eph R ober t s accep t ed a q u e ry

.

in t h e A m e ri can Ph ar m ac e u t i cal A s s o ci at i o n as follo w s ,

Wh at i s th e be st for m u l a fo r Eli xir o f V aleri anat e o f

A mm o n i u m w h i ch s h all be n e arl y fre e fro m v aleri an i c
,

odor an d e l eg an t l y aro m at i z ed "

, H av i ng failed t o re
p y
l ,
i n 1 8 6 5 M r J F a ri s M oor
. e .g av e a for m u l a t o t h e

S o c ie ty w hi ch i n s u b st an c e agr e ed w i t h t h at o f M r E n o s
, .
,

t h e pri n c iple b e i n g t h e for m at io n o f v aleri anat e o f am

m o n i u m fro m v aleri an i c ac i d b y sat u r at i n g i t w i t h car ,

bo n at e o f am m o n i u m A t t h i s d ay v aleri anat e o f am
.

m o n i u m i s e m plo y ed i n st e ad o f t h e v aleri an i c ac id .

E L I XI R O F V A L ER I A N A T E O F A M M O N I U M W I TH CIN
CH O N ID IN E .

( Eu xm V A LE R I A N A I E or A mmo m a w r r u C m c u o m n m )
’ ‘

or .

C i n c h onidi ne ( A l k al o i d) {2 8 g r ai n s
El i x i r of V al e r i a n a t e of A m m on i u m , A c et i c A c i d , of

e a c h a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e c i n cho n idi ne i n a m or tar w i t h ace t i c

ac id i n am o u n t su ffi c i e n t t o e ffe c t i t s sol u t io n an d ad d
, ,

t o t hi s liq u id e lixi r o f v al e ri an at e o f am m o n i u m u n t i l
t h e prod u c t m eas u r es s ix t ee n fl u id o u n c e s I f no t o f .

ac id r eact io n add cau t io u s l y ace t i c ac id u n t il i t w ill

,

r e dd en bl u e li t m u s p ap e r an d fi l t er i f n e ce ssary .

Each fl u id drach m ( t easpoo n fu l ) o f t h e fi n i s hed elixir

c o n t ai n s t w o gr ai n s o f v al e ri an at e o f am m o n i u m an d ,

o ne grai n o f ci n c ho nidi n e as t h e a ce tat e o f t h at alk aloid, .

A l l o f t h e c ombi n at i on s o f v al er i anat e o f am m on i u m an d t h e al al oi d s i n e l i x i r k
for m s h o u l d h av e an ac i d r e ac t i on I t i s , t h e r e fo r e , t o b e u n d e r s t oo d w i t h t h e o r m u l a f
f k
.

o f t hi s c h ar ac t e r wh i c h o ll ow , t ha t i n c as e t h e el i x i r i s al al i n e i t m u st b e ac i d u l at e d
Wi t h ac eti c aci d
34 ELI XIR F O R M U LE .

EL I X I R O F V A L E R I A N A T E O F A M M O N I U M W I TH C IN
CH O N ID IN E AN D P YR OP H O S P H A T E O F I R O N .

( Eu xm or V LER N TE
A IA A OF A MM NO IA w rr u C m c u o m m a A N D I R N)
O .

El i x i r of V al eri a n at e of A m mon i u m w i t h C i n c h on i
dine 8 flu i d o u n c es

El i xi r of V al eri a n at e of A m m on i u m w i t h P e p h o s

p h a te of I ron

Mix t he m t oge t h er .

E ach fl u i d d rac h m ( t ea spoo nfu l ) o f t h e fi n i shed elixir

c o n tai n s t w o gr ai n s o f v aleri anat e o f amm o n i u m o ne ,

grai n o f p y ro p h o sp at e o f i ro n an d o n e h al f grai n o f ci n -

ch o n id i n e t h e l at t er i n t h e for m o f an ace tat e

, .

C AU T IO N .
— Ex cess o f aci d will c au se th e p yro p h ospate of i ro n to gel at
i niz e. Ex cess o f al k al i p r ec i p i t at es th e ci n ch on i d i n e . Th e e l i x i r sh ou l d
b e m ad e as n ear l y n eu t ral as p ossi b l e , an d r e m ai n t r an sp aren t, b y th e us e

of aceti c aci d and am m o n i a w ater , as i n d i cated b y l i t m u s p aper .

0
E L I XI R O F V A L E R I A N A T E O F A M M O N I U M W I TH C IN
’

C H O N I D I N E , P YR O P H O S P H A T E O F I R O N
AN D S T R YC H N I N E .

( Eu x m OF V LE R N TE
A IA A or A MM NO IA, Cc n om m x , I R N
O AND S T RYCHN IA. )
El i x i r of V al e ri an at e of A m m o n i u m w i t h C i n c h on i
d i ne 8 flu i d ou n c es

El i x i r of V al e ri a n a t e of A m m o n i u m w i t h P y rop h os
p h a t e of I ro n
S t ry c h n i n e 2 12 g ra i n s
A c et i c A c i d , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e s t ry ch n i n e i n a m or tar w i th ace t i c acid ,

i n am o u n t s u ffi c i e n t t o e ffe ct i t s s ol u t io n an d add t hi s t o ,

t h e elixir s h av i ng pre v io u s l y m ixed t he m t oge t her

, U se .

pre cau t io ns s u gge st e d w i t h e lixir o f v al e ria nat e o f am

m o n i u m w i t h c i n cho n idi n e an d p y roph o s ph at e o f i ro n .

Each fl u id drac h m ( t eas poo n fu l ) o f t h e fi n i shed e lixir

co n tai n s t w o grai n s o f v aleri an at e o f am m o n i u m o n e h al f -
 EL I XI R F O R M U L/E .
35

grai n o f p y ropho sph at e of iro n o ne h al f grai n of ci n

,
-

c h o n id i n e , an d o n e -
fi ft i e t h grai n o f st r y ch n i n e The al .

k al o i d s exi s t e
as ac tat e s .

EL I XI R O F V A L ER I A N A T E O F A M M O N I U M W I TH CIN
CHO N IN E .

( Eu xtn or V LER N TE
A IA A or A MM N
O IA w xr u CI NCH N
O IA .
)

C i n c h on i n e A l k al o i d ) 1 28 g rai n s

El i x i r of V al eri a n a t e of A m m on i u m , D i l u t ed A c et i c
A ci d , o f ea c h a s u fli c i en t q u an t i ty .

Tri t u rat e t h e c i n cho n i n e i n a m or tar w i t h t h e ace t i c ,

ac id i n am o u n t s u ffi c i e n t t o e ff c t i t s s ol u t io n an d m i x
e

w i t h t hi s elixi r o f v al e ri an at e O f amm o n i u m u n t il t h e ,

prod u ct m e as u re s s ix tee n fl u id o u n ce s I f n o t o f acid .

re ac t io n ad d cau t io u s l y ace t i c ac id u n t il i t w ill redde n

,

li t m u s p aper an d fi l ter i f n e ce s sary

,
.

E ach fl u id d rach m ( t e aspoo n fu l ) o f t h e fi n i shed elixi r

c o n t ai n s t w o grai n s o f v al e ri an at e o f am m o n i u m an d ,

o n e grai n o f c i n c ho n i n e as t h e ac e tat e O f t h at alk aloid

, .

E L I XI R O F V A L E R I A N A T E O F A M M O N I U M W I TH CIN
CH O NIN E AN D YR O P H O S P HA TE
P O F I RO N .

( Eu xm OF V L E R N T E A MM N C NCH N
A IA A OF O I A, I O IA AND I R N)O .

Eli xi r of V al e ri a n at e of A m m o n i u m w i t h C i n c h on i n e 8 . flu i d o u n c es

El i x i r of V al eri a n a t e of A m m on i u m w i t h P e p h os
p h a t e of I ro n

M i x t h em t og e t h e r . U s e p r ecau t io n s s u gge st ed w i t h
elixi r o f v al e ri an at e o f am m o n i u m w i t h c i n c ho n idi n e an d

p y ropho sph at e o f iro n .

Eac h fl u id d rach m ( t easpoo n fu l ) o f t h e fi n i shed elixir

c o n tai n s t w o grai n s o f v al e ri an at e o f am m o n i u m o ne ,
 3 6 ELI XIR F O R M U LIE .

gr i a n p y ropho ph e
of s at Of i ro an d o n e h al f grai n
n, -
of

c i n c ho ni n e as t h e ace tate
, o f t h at alk aloid .

EL IXI R O F V A L ER IA N A T E O F A M M O N I U M W I TH CIN
C H O N I N E, P Y R O P H O S P H A T E O F I R O N
AN D S T R YC H N I N E .

( Eu xtn or V L E R N TE
A IA A or A MM NO I A, C l N C HO N I A , I R N O AND S T RYCHN IA .
)
El i x i r of V a l eri an at e of A m m on i u m w i t h C i n c h o
n i n e an d Pe p h O S p h a t e of I ro n 16 flu i d o u n c es

S t ry c h n i n e g r a i n s

A c et i c A c i d , a s u ffi ci en t q u a n t i t y .

Tri t u rat e r y ch n i n e i n a m or tar w i th ace t i c ac id

the st ,

i n am ou n t s u ffi c ie n t t o e ffe c t i t s sol u t io n an d t he n ad d ,

t h e elixi r o f v aleria nat e o f am m o n i u m w i t h c i n c ho n i n e

an d p y ropho s pha t e o f iro n O b ser v e pre cau t io n s s u g
.

ge st ed w i t h elixi r o f v aleri anate o f a m m o n i u m w i t h ci n

c h o n i d i n e an d p y ropho s ph at e o f iro n .

Each fl u id drach m ( te aspoo n fu l ) o f th e fi n i shed elixir

c o n tai n s t w o grai n s o f v aleri anat e o f am m o n i u m one ,

grai n o f p y ropho sph at e o f iro n o ne h al f grai n o f c i n cho ,

-

n i n e an d o n e fift i e t h o f a gr ai n o f s t ry c h n i n e
,
-
The alka .

loid s exi st as a ce tat es Thi s preparat io n sho u ld be as

.

n e arl y n e u t ral i n re act io n as i t i s po ss ible t o m ake i t .

E L I X I R O F V A L ER I A N A T E O F A M M O N I U M W I TH C I N
CH O N IN E AN D S T RYC H N I N E .

( Eu x m or VA a AN A rs
'
or A MM N O I A, CI NCH N O IA A ND S T RYCHN IA .
)
El i xi r of V al eri an at e of A m m on i u m w i t h C i n c h o
nine 1 6 fl u id ou n c e s

S t ry c h n i n e 2 z g r a i n s

A c et i c A c i d , a s u ffi c i e n t q u an t i ty .

Tri t u rat e th e r y ch n i n e i n
st a m or tar w i t h , e i
ac t c ac id
in s u fl i ci e n t
‘
a m o u n t t o e ffe ct its s ol u t io n , t he n ad d t h e
 EL I XI R F O R M w as .
37

elixir o f v aleri an at e o f amm o n i u m w i t h ci n cho n i n e an d ,

fi l t er i f n e cessar y I f n o t o f ac id r eact io n ac id u l at e
.
,

s ligh t l y w i t h ace t i c ac id .

E ach fl u id drac h m ( t e aspoo n fu l ) o f t h e fi n i s hed elixir

co n t ai n s t w o grai n s O f v al e ri an at e o f am m o n i u m one ,

grai n o f ci n cho n i ne and o n e fi ft i et h o f a grai n o f st r y c h

,
-

n i n e as t h e ac e tat e o f t h at alk aloid

,
.

EL I XI R O F V A L E R I A N A T E O F A M M O N I U M W I TH
YR O P H O S P H A T E O F
P I RO N .

( EL X R
I V LER N TE A M M N
I OR A IA A or O IA A ND I R N)
O .

El i x i r of V a l e ri a n a t e of A m m on i u m 8 flu i d ou n c e s

El i x i r of Pe h
p os p h at e of I ron 8

M i x t he m t oge t her .

Each fl u id drach m ( t easpoo n fu l ) o f t h e fi n i shed elixir

co n t ai n s o n e grai n eac h o f v al e ri an at e o f am m o n i u m an d

o f p y ropho s ph at e o f iro n I t s ho u ld h av e a s ligh t l y alk a

.

li ne re ac t io n .

EL I XI R O F V A L ER I A N A T E O F AM M O N IU M AN D Q UI
N IN E .

Qu i n i n e ( A l k al o i d ) 1 28 g rai n s
El i x i r of V al eri a n at e of A m m o n i u m , D i l u t e d A c et i c A c i d ,
of e a c h a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e q u i n i n e i n a m or tar w i t h a s u ffi c ie n t ,

am o u n t o f t h e ac e t i c ac id t o e ffe c t i t s s ol u t io n t he n m i x ,

t h e liq u id w i t h e n o u gh elixi r o f v aleri an at e o f am m o

n i u m t o prod u c e s ix t e e n fl u id o u n c e s I f n o t o f ac id re .

act io n ad d ace t i c ac id u n t il i t w ill c h an ge t h e c olor o f

,

bl u e li t m u s p aper t o red .

E ac h fl u id drach m ( t eas poo n fu l ) o f t h e fi n i shed eli xi r

3 8 ELI X IR F O R M U La .

co ntai ns tw o grai ns of va leri anat e of am m o ni u m , an d

o n e g rai n o f q u i n i n e , as t h e ace tat e of t h at alk aloid .

E L IX I R O F V A L E R I A N A T E O F A M M O N I U M W I TH Q UI
NIN E AND CINC HO N ID INE .

( Eu x xR o r V LER N TE
A IA A OF A mmo N t A w r m Q U l N-
IA A ND Cc uo m ot A )
.

El i x i r of V al e ri an at e of A m m on i u m an d Qu i ni n e 8 flu i d ou n c es

El i x i r of V al eri an at e of A m m on i u m an d C i n c h on i
dine

M i x the m og et her t .

Each fl u id dr ach m ( t e aspoo nfu l ) o f t h e fi n i she d elixi r

c o n tai ns t w o gr ai n s o f v aleri anat e o f am m o n i u m an d ,

o n e h al f grai n e ac h o f q u i n i n e an d c i nc ho n idi n e as ac e
-
,

tat e s o f t he s e alk aloid s .

E L I XI R O F V A L E R I A N A T E O F A M M O N I U M W I TH Q UI
N I N E, C I N C HO N I D I N E A N D S T RYC H N I N E .

( Eu xm o r: VA LER N TE
IA A or A M M O N tA , Q U t N i A, CI NCH N DO I IA AND S T RYCHN IA .
)

S t ry c h n i n e
El i x i r of V al eri an at e of A m m on i u m w i t h Qu i n i n e
an d C i n c h on i d i n e 1 6 flu i d ou n c e s

A c et i c A c i d , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e st ry ch n i n e i n a m or tar w i th ac e t i c ac id ,

i n s u ffi cie n t am o u n t t o e ffe c t i t s s ol u t io n t h en m i x w i t h ,

t h e elixir o f v al e ri an at e o f am m o n i u m w i t h q u i n i n e an d

c i n chonidi n e .

E ach fl u id drach m t e as poo n fu l ) o f t h e fi n i sh e d elixir

c o n tai n s t w o grai n s o f v al e ri anat e o f am m o n i u m o ne ,

h al f grai n each o f q u i ni n e an d ci nchon idi n e an d o n e fi f ,

-

t i e t h o f a grai n o f s t r y c h n i n e The alk aloid s are i n th e

.

for m o f ac e tat es .
 EL I XIR F O R M U LZE .
39

E L I XI R O F V A L E RI A N A T E O F A M M O N I U M TH Q W I UI
N I N E, CIN C HO N ID IN E P YR O P H O S P H A T E
,

O F I R O N A N D S T R YC H N I N E .

( Eu xm O F V A LE R t A N A r n
'
OF A mmo N t A , QU N
1 1A, C 1 N C H0 N 1 D 1A, I R N
O AND S T RYCHN IA )
.

Eli x i r of V al e ri a n at e of A m mon i u m w i t h Qu i n i n e an d
Pe p h O S p h a t e of I ron 8 flu i d ou n c es

El i x i r of V a l eri a n at e of A m m o n i u m w i t h C i n c h on i
dine an d P y rop h os p h a t e of I ron 8 flui d ou n c e s

S t ry c h n i n e

Tri t u rat e th e s t ry ch n i ne i n a m or tar w i t h ace t i c acid ,

i n s u ffi cie n t q u an t i t y t o e ffec t i t s s ol u t i o n an d ad d t h i s t o ,

t h e elixir s h av i n g pre v io u s l y m ixed t he m t oge t her ; an d

,

fil ter i f n e ce ssar y .

Each fl u id drach m ( t easpoo n fu l ) of th e fi n i s hed elixir

c o n tai n s t w o grai n s o f v aleri an at e o f am m o n i u m one ,

fo u r t h grai n e ac h o f q u i n i n e an d ci n ch o n idi n e o n e grai n ,

o f p y ropho sph at e o f iro n and o n e fift i e t h grai n o f s t r y ch

,
-

n i ne The alk aloid s exi s t as ac etat e s Thi s e lixir sho u ld

. .

be as ne arl y ne u t ral as i t i s po ss ible to m ake i t .

E L I XI R O F V A L ER I AN A T E O F A M M O N I U M W IT H Q UI
N IN E AN D CIN C HO N IN E .

(E LXR
I I or V LER N TE
A IA A or A mmo N t A w r m QU N I IA A ND CI NC H N O IA .
)

of V al eri a n a t e of A m m on i u m Qu i n i n e flu i d
'

B lix t an d . . 8 ou n ces

El i x i r of V al eri a n a t e of A m m on i u m w i t h C i n c h o n i n e 8 .

M i x t he m t oge t h e r .

Each fl u id d rach m ( t e aspoo n fu l ) o f t h e fi n i sh e d elixi r

c o n tai n s t w o grai n s o f v a l e ri an at e o f am m o n i u m an d ,

o n e h al f gr ai n e ac h o f q u i n i n e an d c i n c hon i n e as ace
-
,

tat e s o f t he se alk aloid s .

4 0 EL I XIR F O R M U LAQ .

E L IXI R O F V A L ER I A N A TE O F A M M O N I U M W I TH Q UI
N I N E, C I N C H O N I N E A N D S T RYC H N I N E .

( Eu xi R or VA LER N TE
IA A OF A MM NO IA, Q UtN i A AND S T RYCHN I A .)

El i x i r of V a l eri a n a t e of A m m on i u m w i t h Qu i n i n e
an d C i n c h on i n e 16 flui d ou n c e s

A c et i c A c i d , a s u ffi ci e n t q u an t i t y .

Tri t u rat e t h e s try ch n i n e i n a m or tar w i t h ace t i c ac id ,

i n am o u n t s u fli c i e n t to e ffe ct i t s s ol u t io n an d ad d t hi s t o ,

t h e elixir o f v aleri anat e o f am m o n i u m w i t h q u i n i n e an d

c i n cho n i n e .

Each fl u id drach m ( t e aspoo n fu l ) o f t h e fi n i shed e lixi r

c o n tai n s t w o grai n s o f v aleri an at e o f am m o n i u m o ne ,

h al f grai n each o f q u i n i n e and c i n cho n i n e an d o ne fi ft i eth ,

-

o f a gr ai n o f s t ry ch n i n e The alk aloid s exi s t as ac e

.

t at e s .

E L I XI R O F V A L E R I A N A T E O F A M M O N I U M W I TH Q UI
N IN E AN D YR O P H O S P H AT E O F I R O N
P .

( EL1x 1 R OF V L E R N T E A mm
A IA A w
OR QU N IR N )
oN tA rr u I IA AND O .

El i xi r of V al eri an at e of A m m on i u m w i t h Qui n i n e . . 8 flu i d ou n c es

Eli xi r of V a l eri a n at e of A m m o n i u m w i t h P y ro p h o s
p h a t e of I ron 8

M i x t h e m t og e t h e r .

Each fl u id drach m ( t e as poo n fu l ) o f t h e fi n i sh e d e lixi r

c o n tai n s t w o gr ai n s O f v al e ri an at e o f am m o n i u m an d

o n e h al f grai n e ac h o f p y ropho sph at e O f iro n an d q u i

-

n i ne .O b s er v e t h e pre cau t io n s s u gge st ed w i t h elixir o f

v aleri an at e O f am m o n i u m w i t h c i n c ho n idi n e an d p y ro
pho sph at e O f iro n .
4 2 E LI XI R F O RM U LJE

E L I XI R OF V A L ER I A N A TE OF AM M O NIU M W IT H
S T RYC H N I N E .

El i xi r of V al e ri a n a t e of A m m on i u m 1 6 flu i d ou n c e

A cet i c A ci d , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e st r y ch n i ne i n a m or tar w i t h ace t i c acid ,

i n s u ffi c ie n t am o u n t t o e ffe ct i t s s ol u t io n an d m i x t hi s ,

w i t h t h e e lixir o f v aleri an at e o f am m o n i u m I f n o t of .

ac id re ac t io n ad d e n o u gh ace t i c ac id t o ch an ge bl u e l i t
,

m u s p ap e r t o red .

E ac h fl u id drach m ( t e aspoo n fu l ) o f t h e fi n i shed elixi r

c o n tai n s t w o gr ai n s o f v aleri an at e O f amm o n i u m an d ,

o n e fift i e t h o f a gr ai n o f s t r y ch n i n e as an ace tat e O f t ha t

-

alk aloid .

EL IX I R O F V A L ER I A N A TE O F A M M O N I U M W I TH
SU M B U I

( E LXR I I OF V LE R N TE
A IA A OF A mmo N t A w n '

n M u sk R O O T ) .

F l u i d E x t ra ct of S um bul . 2 flu i d ou n ces

Elixi r of V al e ri a n at e of A m m on i u m
C a rb o n a t e of M ag n e s i u m , a s u fli c i e n t q u an t i ty .

Tri t u rat e t h e fl u id e x t ract o f s u m b u l i n a cap ac io u s

m or tar w i t h carbo n at e o f m ag n e s i u m i n am o u nt s u ffi
,

c ie n t t o for m a c r e am y m ix t u re t h e n gr ad u all y ad d t h e ,

e lixir o f v al e ri an at e O f am m o n i u m s t i rri n g w e ll an d fi l t e r , , .

Eac h fl u id dr ach m o f t h e fi n i shed e lixir repr e sen t s t w o

grai n s o f v al e ri an at e o f am m o n i u m an d accordi n g t o t h i s ,

for m u l a each fl u id drac h m sho u ld c o n tai n t h e act i v e pri n

c i p l e s o f se v e n an d a h al f m i n i m s O f fl u id ex t r ac t o f s u m

bul . B u t as a m at ter o f fact t h at am o u n t w ill n o t d i s

, ,

s ol v e i n t h at q u an t i t y o f t h e m e n s t r u u m t h e ex ce s s ,

re m ai n i n g i n th e fil t er p aper .
 121 1t F O R M U L/E
, .
43

E L I XI R A N T I G L A I R EU X .

( Eu xm F O R G LE N O R R H GZ A . L A V O Lu t v
’
s P U RG A N
‘
VE Eu xtn TI NC T UR A P U RGG A s .

TI NC T UR A J
A L A P /E C O M Po s r r A s l

J al ap 8 t roy o u n ce s

T u rp et h R oot 1

S c am m on y 2

D i l u t e d A l c oh ol 96 flui d ou n c e s

M ix d r u g s and red uc e t he m t o a c oarse po w der

th e ,

an d m ace rat e t hi s i n t h e dil u t ed al c ohol fo r t e n d ay s

'

st irri n g t h e m ix t u re t horo u ghl y e ach d ay ; t h e n fil t er .

( A me ri can Jo u r n al of P h armacy ,

E L I X I R A N T I G O U T T E U X D E V I L L E TT E .

( B 11 V LL E TT E G U T
I
'
S O Eu x rR .
)

B row n C i n c h on a B a rk 25 t roy ou n c es

P op p y P et al s .

S as s afra s B ark
G u a i ac R es i n

S y ru p of S a rs ap ari l l a

M i x t h e dr u g s red u ce t he m t o a co ar se po w der
an d ,

an d m acerat e i n t h e pre v io u sl y m ixed j am ai ca r u m an d

sy r u p o f sar sap arill a fo r fo u r t ee n d ay s st irri n g t h e m i x ,

t u re t horo u ghl y e ac h d ay t he n fil t er .

( HAGB R . S e e N e w R eme d i e s,
44 ELI X IR F O R M U L/E .

A R O M AT I C EL I X I R .

F l u i d E x t ra ct of S w eet O ran g e P e el flui d ou n c es

F l u i d Ex t ra c t of C o ri a n d e r S e e d f
F l u i d E x t rac t of A n g el i c a S e ed 4
5
S i m pl e Eli xi r
C arm i n e C ol or, C arb on a t e of M ag n e s i u m , of e ac h

a s u ffi c i e n t q u a n t i ty .

Mix fl u id ex t ract s an d t ri t u rat e t he m i n a cap a

the
ci o u s m or tar w i t h carbo nat e O f m ag n e s i u m i n am o u n t
,

su f fi cie n t t o for m a c re am y m ix t u r e t he n grad u all y ad d .

t h e s i m ple elixir s t i rri n g w ell an d fil t er

,
L ast l y ad d
,
.
,

sol u t io n o f c ar m i n e e n o u gh t o i v e a n i c e red c olor

g .

Thi s elixi r i s u sed as a fl av or an d may be u se d i n ,

s t e ad o f s i m ple elixi r i f de s ir e d as i t i s acce p t able t o,

m an y per s o n s The N ew ark Ph ar m ace u t i cal A sso c i at io n

.

( 1 8 71
) re c o m m e n ded a for m u l a o n w h i ch t h e abo v e i s

b ased .

EL IXI R O F I O D I D E O F A R S EN I C A N D M ERC U RY

S o l u t i on of I od i d e of A rs e n i c an d M erc u ry ( D o n o v an s
’
So
l ati on ) . 2 56 m inim s
S i m p l e E l i x i r, a s u ffi c i e n t q u an t i ty .

M i x th e s ol u t io n io dide o f ar se n i c an d m ercu ry w i th
of

e n o u gh s i m pl e e lixir t o prod u ce s ix t e e n fl u id o u n c e s .

Each fl u id d rach m o f th e fi n i sh ed elixir c o n tai n s t w o

m i n i m s o f s ol u t io n o f iodide o f ar se n i c an d m e r cu r y .

D o s e o n e fl u id drach m ( t e as poo n fu l ) i nc re ased care

, ,

fu ll y t o t w o or t hree fl u id drach m s i f n e ce ssary , .

 ELI XIR F O R M U LE .

EL I X I R O F B E E F .

E x t ract of B eef 2 56
g r a i n s

S i m p l e El i x i r 1 5 flu i d o u n c es

D i s t i l l ed W at er

Tri t u rat e t h e ex t ract O f bee f w i t h t h e w at er t h e n ,

grad u all y ad d t h e s i m ple e lixir an d fi l t er ,

.

Each fl u i d drach m t easpoo n fu l ) o f t h e fi n i s hed elixir

c o n tai n s t w o grai n s o f ex t rac t o f be e f Thi s for m u la .

w as b ased o n o n e gi v e n i n t h e D rugg zlrts Ci r cu l a r 1 8 78

’

.
,

EL I XI R O F B E E F A N D CI TRATE O F IRO N .

(E LXR
I I or B as s AND I R N)
O .

El i x i r of B eef 1 6 flui d ou n ce s

W a t er }é
C i t rat e of I ron an d A m m on i u m g ra i n s

D i ss ol v e t h e c i t rat e
iro n i n t h e w at er ad d t h e elixir
of ,

O f bee f an d fil t er i f n e c e ssar y
, .

Eac h fl u id drac h m ( t e aspoo nfu l ) o f t h e fi n i shed elixir

c o n tai n s t w o grai n s o f e x t r ac t O f bee f an d o n e grai n o f

c i t rat e o f iro n .

Thi s prep arat io n i s far fro m per m an e n t I t depo si t s a .

pre cipi tat e by age w h i c h e v ide n t l y re su l ts fro m t h e reac

,

t io n be t w ee n t h e chloride o f s od i u m pre se n t i n l arge ,

am o u n t i n t h e b e e f ex t ract an d t h e c i t r at e o f iro n
,
The .

s u b st i t u t i o n o f c hloride o f i ro n fo r t h e c i t r at e m igh t
pro v e ad v a nt ageo u s b u t t h e de m an d i s for an elixi r of
,

bee f w i t h ci t rat e O f iro n .

4 6 E LI XIR F O R M U L/E .

EL IXI R O F B EEF , I RO N A N D CIN CHO N A .

El i x i r of B ee f w i t h C i t ra t e of I ro n 8 flu i d ou n ce s

El i x i r of C i n c h on a ( A l k al o i d al ) 8

M i x t h em t oge t her .

E ach fl uid drach m ( t e as poo n fu l ) o f t h e fi n i s hed elixir

c o n ta i n s o n e grai n o f e x t rac t o f bee f an d repre s e n t s t w o

gra i ns of o ffi ci nal cal i saya bark .

 ELI X IR F O R M U LE .
47

E L I X I RS C O NTA I N I N G A M MO N I O -
C IT R ATE
OF BI SM UT H .

A m m o n io c i t rat e o f bi s m u th i s n o t al w ay s e n t irel y s ol u
-

ble i n w ate r o w i n g t o t h e fac t t h at i t p ar ts w i t h am m o n ia

,

an d as s u m e s a p ar t i all y i n sol u ble c o n di t io n I t i s w ell .

,

t here fore t o re m e m ber t h at a li t t le amm o n i a w at er w ill

,

fac i li tat e t h e c o m ple t e s ol u t io n O f am m o n io c i t rat e o f -

bi sm u t h u n le ss t h e de co m po si t io n h as pro ceeded be y o n d
,

a cer tai n li m i t .

I n co n siderat io n o f t h e abo v e fact elixir s co n tai n i n g ,

ex ce ss o f acid s are i nco m p at ible w i t h i t an d t h e sam e i s ,

t r u e o f sol u t io n s o f sal t s o f t h e m i n eral ac id s H o w e v er .

,

ex ce ss o f ace t i c aci d doe s n o t d ec o m po se i t i m m edi at e

l y an d sal t s o f ace t i c ac id are c o m pa t ible w i t h s ol u t io ns
,

O f amm o n io c i t rat e o f bi s m u t h
-
w hi ch i s o n e r e as o n w h y
,

w e u se ac e t i c ac id i n m aki ng sol u t io n s o f alk aloid s .

I f an elixir c o n tai n i n g am m o n io c i t rat e O f bi sm u t h i n

-

c o nn e c t io n w i th pep s i n i s n o t alk ali n e i n re ac t io n or at ,

le ast n eu t ral de co m po s i t io n o f t h e sal t re s u l t s follo w ed

, ,

b y pre c ipi tat io n I f i t i s alk ali n e de st r u ct io n O f t h e pep

.
,

s i n follo w s .

I f an elixir c o n t ai n i ng am m o n io c i t rat e O f bi s m u t h -

an d sal t s o f t h e alk aloid s i s alk ali n e t h e alk aloid s are

,

likel y t o pre cipi tat e ; an d i f acid pre cipi tat io n r e s u l ts

,

fro m de c o m po s i t io n O f t h e bi s m u t h sal t The s e i n co m .

p a t i b l e s can o n l y be as s o c i at ed b y car e fu ll
y a v oidi n g a n y
c o n s iderable ex c e s s o f ei t her ac id or alk ali The alk ali t o .
4 8 ELI XIR F O R M U LA ;

be u se d order to e ffec t n e u t ralizat io n i s am m o ni a

in
w at er an d t h e ac id ac e t i c ac id
, , .

We call atte n t io n o ccas io n all y t o t h e abo v e fact s i n ,

c o nn e ct io n w i t h spe c i al c o m bi nat io n s w hi ch w e are for c ed

t o c o n s ider and w e t r u s t t h at t h e repe t i t io n w ill be ex

,

c u se d as w e pre fer t o r e pe at r at her t h an o m i t a w ord

,

o f w ar n i n g w here i t m ay be n e c e ssar
y .

EL I XI R O F C IT RAT E O F A M M O N I U M A N D B ISM U TH .

Eu xm or A M M O N to -C t r RA T a on 8 15 1 1 11 1 1 1 . Eu xtR o r B M UTH )
IS .

m
Am o n i o - C i t ra
te of B i sm u th 2 56 g rai n s

S i m p l e El i x i r , A m m o n i a W at er , o f ea c h a s u f c i e n t fi q u an
t i ty .

D i ol e
ss v th e am m
o n io c i t rat e O f bi sm u t h i n t w el v e
-

fl u id o u nce s of si m pl e elixir addi ng cau t i o u s l y e n o u gh ,

a m m o n i a w a t er t o re n der t h e sol u t io n sligh t l y alkali n e ,

t he n bri ng t o t h e m e as u r e o f s ix t ee n fl u id o u nce s b y t h e
addi t io n O f a s u ffi c ie nt q u an t i ty o f s i mpl e elixir .

Each fl u id drach m ( t eas poo n fu l ) o f t h e fi n i shed elixir

repre s e n t s t w o grai n s o f am m o n io ci t rat e o f bi sm u th -
,

an d i s t h e sam e i n st re n gt h as t h at adop t ed b y t h e A m e r

i can Ph ar m ace u t i cal A sso c i at io n 1 8 75 D u ri ng w ar m ,

.

w e at her t h e amm o n i a e scap es t o a gre at er or l ess ex t e n t

fro m sol u t io n s o f am m o n io ci t rat e o f bi s m u th ; he n c e -

t h e add i t io n o f t h e am m o n i a w at er i n order t o i ns u re a
perfe ct s ol u t io n Sho u ld t hi s elixir be co m e c lo u d y fro m
.

e scap e o f am m o n i a t h e addi t io n o f a li tt le am m o n i a
,

w at e r w ill re st ore i ts t ran s p are n cy I t i s i n c o m p at ible .

w i t h ac id s and sal ts o f t h e m i n eral acid s The fir st fo r .

m u l a b ro u gh t t o o u r at t e n t io n fo r an el ixir o f bi sm u th , ,

w as b y Mr W m C Bake s i n t h e Amer i can j our nal of

. . .
,

Phar macy , 1 8 67 .
50 ELI XIR F O R M U LJE .

E L I X I R O F C I T RA T E O F A M M O N I U M A N D B ISM U TH
W I TH P EP S IN AN D S T R YC H N I N E .

( 121
. 1l O P A MM O NI CI
O- T R ATE B M or IS I T H,
'
Ps ps AN S T RY C H N
D IA. Eu xm or

PE N B M TH
PS I , IS U AND S T RYCH ) NIA .

El i x i r of C i t ra t e of A m m on i u m an d B i sm uth w i th
P ep s i n . 16 flu i d ou n c es

S t ry c h n i n e . 2
% g r a i n s

A c et i c A ci d , a su fl i ci en t q u an t i ty .

Tri t u rate th e s t r y ch n i ne i n a m ortar w i t h ac e t i c acid ,

i n s u ffi cie n t am o u n t t o e ffe ct i t s sol u t io n an d t he n ad d ,

t h e elixir O f c i t rat e o f am m o n i u m and bi s m u t h w i t h

pep si n If o f a c id re act io n cau t io u sl y add am m o n i a
.
,

w at er u n t il i t i s n e u t ral or e v e n s ligh t l y alk ali n e .

Each fl u id drach m ( t e as poo n fu l ) O f t h e fi n i shed elixir

c o n tai n s o n e grai n e ac h O f pep s i n and am m o n io c i t rat e -

o f bi s m u t h an d o n e fift i e t h grai n o f s t r y c h n i n e
.
-
.

The r e mark s w e h av e m ad e co ncern i ng st r y ch n i ne an d

pep s i n i n t heir re sp e ct i v e po s i t io ns w ill appl y w i t h per
, ,

t i n en ce t o t hi s prep arat io n an d al t ho u gh t hi s el ixi r e m ,

b race s a mass o f i nco n gr u i t i es i t i s a m o ng th e m o st pop ,

u l ar e lixirs u sed b y p h y s i c i an s Were i t no t fo r t hi s fac t .

t h e co m bi nat io n sho u ld n o t h av e a p o si t io n i n o u r book .

EL I XI R O F C I T RA T E O F A M M O N I U M AN D B IS M U T H
W I TH S T R Y C H N I N E .

’
E1 . 1x 1 R o r A mM O N l O -C I T R AT E or B M UTH
IS AND Se c uNt A . Fl u x xR o r B M UTH
IS

A ND Se cuNtA .
)

El i x i r of C i t rat e of A m m on i u m w i t h B i s m u t h 1 6 flu i d ou n c e s

S t ry c h n i n e 2 5 g ra i n s

A c et i c A c i d , a s u ffi c i en t q u an t i t y .

Tri t u rat e th e st ry c h n i n e i n a m or tar cau t io u s l y addi ng ,

a ce t i c acid u nt il t h e alk aloid i s di ssol v ed t h e n ad d th e ,

elixi r o f c i t rat e O f am m o n i u m w i t h bi sm u t h .
 E LI X IR FO R M U U E .
5 1

Ea ch fl u id drach m ( t e as poo n fu l ) o f t h e fi n i shed elix i r

c o n ta i n s t w o grai ns o f c i t rat e o f am m o n i u m and bi s
m u t h and abo u t o ne fi ft i e t h o f a grai n o f s t ry ch ni n e as
,
-

t h e ac e t at e o f t h at alk aloid .

S try ch n i n e i s i nco m pa t ible w i t h alk ali n e s ol u t io ns and ,

i f a pre c ipi tat e s ho u ld o cc u r w hi le th e eli x ir h as an alka

li ne reacti o n car e m u s t be take n t hat t hi s pr ecipi ta t e i s
,

t horo ughl y m ix e d w i t h t h e liq u id be fore e ac h do s e i s ad

m i n i stered I n asm u c h as t h e amm o n io c i t rat e o f b i s
.
-

m u t h i s i nc o m p at ibl e w i t h an ac id t hi s e lixir m u st h av e ,

an alkali n e or at le as t a n e u t r al re act io n H o w e v er al .
,

t ho u gh t w o an d o ne h al f gra i n s O f st ry ch n i n e re fuse s t o
-

di ssol v e i n s ix t ee n fl u id o u n ces o f w at er i t se e m s t h at ,

t h e m e ns t r u u m c o m po s i n t h i elixir h t h proper t f
g s a s e y o

h o ldi ng i n s ol u t i o n th e st ry ch n i n e e v e n tho u gh i t ( th e ,

e li xir
) i s al kali n e a n d t h u s , t h e ge n er a l i n c o m p at ibili ty
O f t h e c o n st i t u e n t s i s o v er c o m e .

B I TT E R E L I X I R .

( Eu x m A M A R UM )
.

Ex t ract of B u c k -b ea n 2 t roy ou n c es
Ex t ract of O ra n g e P e el 2

D i ssol v e t he m -
in a m ix t u re of

D i l u t e d A l coh ol . 1 6 t roy ou n ces

P e p p e rm i n t W at e r 1 6

A nd add Of

S p i ri t f Et h e r ( H o fl m an An od yne )
'
’
o s 1 t roy ou n c e

Thi s fo r m u l a i s t ha t of the Ger m a n Ph ar m acop oei a ,

1 8 72 .
52 ELI XIR F o R M U La .

E L I X I R O F B L A C K B E R RY .

F l u i d E x t ra ct of B l a c k b e rry 2 flu i d o u n c es

S i m p l e El i x i r .

A l co h o l
C a rb o n a t e of M ag n e s i u m , a s u ffi c i e n t q u an ti ty .

i
c en t t o for m a cre am y m ix t u r e t he n grad u all a dd t h
y e
,

s i m ple e lixir s t irri ng w ell an d fil t er

, , .

E ac h fl u id drach m o f t h e fi n i sh ed elixi rrepre se n t s se v e n

an d o ne h al f m i n i m s o f fl u id ex t ract o f bl ackberr
-
A
y .

fo rm u l a fo r t hi s elixir c o n tai n i n g bla ckberr y roo t c i n

,
-
,

n am o n an d c lo v e s w as s u gge s t ed i n t h e D r u i C i
’

, gg sts r

cu l ar , 1 880 .

EL I XI R O F B O L D O .

F l u i d E x t ract of B ol d o 4 flu i d ou n c e s

S i m p l e El i x i r 12

A l coh ol 2

C arb o n at e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e fl u id ex t ract o f boldo w i t h carbo nat e o f

m agn e s i u m s u ffi cie n t t o prod u ce a c re am y m ix t u re t h e n ,

grad u all y ad d t h e s i m ple elixir fil t er an d ad d t h e , ,

al c ohol .

V e r n e re co mm e nd e d an elixir o f bold o i n t h e P /z ar ma
ceu ti cal j ournal and Tr au sacl i ou s b u t as t h e v ir tu e s o f ,

boldo are i m per fe ct l y e x t ract e d b y an aq u eo u s liq u id w e ,

do n o t ad m ire s u ch a pr ep arat io n A ccordi n g t o t hi s .

for m u l a e ach fl u id drac h m s h o u ld co n tai n t h e ac t i v e pri n

c i p l e s o f s e v e n an d a h al f m i n i m s O f fl u i d e x t rac t o f

boldo . B u t as a m at t e r o f fact t h at am o u n t will n o t

, ,

di ssol v e i n t h at q u an t i t y o f t h e m e nstr u u m th e ex ce ss ,

re m ai n i n g i n t h e fil t er p aper .
 ELI XI R F O R M U LE .
53

EL I X I R O F B RA N D Y .

N u t m eg s 40 g ra i n s
C a rd am on 60

R h u b arb 60

L av e n d e r F l ow e rs 60

C i n n a m on 60

G i n g er 60

P ow d ered E x t ract of Li q u ori c e 3 60

B ra n d y 1 6 fluid o u n c es

W at e r 8

Mix dr u g s an d red u ce t he m t o a co ars e po w der

th e
an d m ac erat e t hi s i n t h e m ixed br an d y an d w at er fo r

fo u rt ee n day s s t irri n g t h e m ix t u re t horo u ghl y e ach d ay

,

t he n fi l ter I t m ay al so b e prep ared by per col at io n

. .

Thi s elixir w as o n ce s old as a proprie tary re m ed y ,

u n der t h e nam e D r B u t ler s Elixi r O f B r an d y We

’ ”
. .
,

are i n for m ed ho w e v er b y a w ri t er i n t h e D m gg zlsts Ci r

’
’

, ,

“
cu l a r t h at D r B u t l e r w as a . fi ct i t io u s ch aract e r ,

c oi n ed b y a c o u ple o f y o u n g m en w h o m ade a sale for

D r Bu t ler s M edi c i n e s
’ ”
. .

E L I XI R O F BUC HU .

F l u i d E x t ra c t of B u ch u 2 flui d ou n c e s

S i m p l e El i x i r
C arb o n at e of M agn es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e th e fl u id e x t rac t o f b u ch u w i t h carbo n at e of

m ag n e s i u m i n s u fl i ci en t am o u n t t o for m a c r eam y m i x
‘

t u re t he n grad u al l y ad d t h e s i m ple e lixir an d fi l t er

, ,
.

A ccordi n g t o t hi s for m u l a each fl u id drac h m s ho u ld

co n t ai n t h e act i v e pri n ciple s o f se v e n an d a h al f m i n i m s

o f fl u id ex t r ac t O f b u ch u B u t as a m at t er o f fact t h at
.
, ,

am o u n t w ill n o t di ss ol v e i n t h at q u an t i t y o f t h e m e n

st ru u m t h e ex ce s s re m ai n i ng i n t h e fi l t er p ape r
, In .
54 E LI XIR F O R M U LE .

ou r opi n io n fl u id ex t ract O f b u ch u sho u ld be m ad e w i t h

,

al c ohol O f t h e s pe c ifi c grav i t y an d t h e ad d i t i o n O f ~

w at er le sse n s i t s v al u e as a m e n st r u u m fo r ex t rac t i n g
b u ch u and re tai ni ng i t s de s irabl e pri n ciple s i n propor t io n ,

t o t h e am o u n t O f w at er added H e n c e i t i s t h at t h e e lixir
.

O f b u c h u i s i n ferior t o an eq u i v ale n t am o u n t o f t h e fl u id

ex t ract o f b u c h u u se d i n maki ng i t pro v idi ng t h e fl u id ,

ex t ract w as rep u table .

E L I X I R O F C I T R A T E O F C A F F EI N E .

C i t rat e of C a ffe i n e 64 g ra i n s
S i m p l e El i x i r 1 6 flu i d ou n ce s

D i ssol v e t h e c i t rat e o f caffe n i e i n th e s i m ple elixir ,

and

fil t er e e ry
if n c ssa .

Th e abo v e i s fro m t h e D ruggrlrts Ci r cu l a r 1 8 78

’
.
,

E ach fl u id drach m ( t eas poo n fu l ) o f t h e fi n i s hed e lixir

c o n tai n s o n e h al f grai n o f c i t r at e O f caffei n e
-
.

E L I XI R O F B RO M I D E O F C A L C I U M .

B rom i d e of C al c i u m 64 0 g rai n s
S i m p l e El i x i r 1 5% flu i d ou n c e s

D i ssol v e t h e bro m ide o f cal ci u m i n t h e s i m ple e lixir ,

an d fi l t e r i f n e ce ssar y .

Each fl u id drach m ( t e as poo nfu l ) O f t h e fi n i shed e lixir

c o n t ai n s fi v e grai n s o f bro m ide o f cal c i u m Thi s propor .

t io n w as re co m m e n ded b y R ob e r t W G ard n e r 1 8 8 0 .
, .

EL I XI R O F I OD O B RO M ID E O
-
F C AL C I U M .

Thi s i s pri v at e proper ty U n der th e abo v e nam e a

.

prep arat io n h as bee n i n t rod u ced an d e x t en s i v e l y ad v er

t i s ed an d t h ro u gh co u r t e sy t o t h e righ t fu l o w n er s w e re
,

frai n fro m i nt erferi ng .

 ELI XI R F O R M U LfE .
55

E L I XI R O F M O N O -B R O M A T E D CAM P HO R .

M o n o- B ro m at e d C am p h or 1 28 g ra i n s

S i m p l e El i xi r 1 5 fl ui d ou n c e s

A l coh ol 1

D i ss ol v e th e m o n o bro m at ed -
phor i n th e al cohol c am ,

an d st ir t h i s sol u t io n sl o w l y i n t h e s i m ple el ixir .

Each fl u id drach m ( t eas poo nfu l ) o f th e fi n i sh ed elixir

c o n tai n s o n e grai n o f m o n o bro m at ed cam phor -
Mr T . . .

M u n d y o f Pari s h as re c o m m e n ded an eli xir o f m o n o

, ,

bro m at ed cam phor c o n tain i ng n i n e grai ns i n fi ft ee n fl u id

drac h m s b u t t h e am o u n t O f al coh ol i s v ery gr e at
,
.

H o w ev e r as al c ohol i s t h e be s t c o mm o n sol v e n t fo r t hi s
,

s u b s tan c e w e pre fer a s i m ple al c ohol i c sol u t i o n t o an

,

elixi r as th e wat er pre se n t i n th e elixir fav or s pre c ipi ta

,

t io n .

E L I X I R C A M P H O R M O N O - B R O M A T ED , CO M P O U N D .

B u ty l O t t al . 3 g ra i n s
E s s en c e of C i n n am on d ra c h m s

D i ss ol v e the b u ty l c hloral i n th e e sse n ce o f c nnam i on

an d add

T i n c t u re of G e l s em i u m mi nim s
Sim ple ( Red ) E l i x i r 1 % fl u i d d ra c h m s

S i m p l e S y ru p , a s u ffi c i en t q u a n t i ty , to m ak e . 1 fl u i d ou n c e

Th en t ri t u rat e t w o
grai ns O f m o n o bro m at ed cam phor -

an d d i ss ol v e i n t h e abo v e liq u id .

A ccordi n g t o t h e P h ar ma ceuti ca l j our nal and Tra nsac

ti ons t hi s elixir i s O ft e n pr e sc rib e d i n Pari s
, .

E ac h fl u id drach m co n tai n s abo u t o n e t hird grai n o f -

b u ty l c hloral o ne m i n i m o f t i n ct u re O f gel se m i u m an d
, ,

o n e fo u r t h grai n o f m o n o bro m at ed cam phor

- -
.
56 E LI X IR F O R M U LIE .

CO M P O U N D C A TH A R T I C E L I X I R .

S i mp l e E l i xi r . 1 4 flu i d ou n c e s

F l u i d E x t ra c t of R h u b a rb 2

S u l p h at e of M ag n es i u m 2 t roy o u n ces

C arb on at e of M a g n es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e fl u id ex t r act o f rh u b arb i n a cap ac io u s

m or tar w i t h carbo n at e o f m ag n es i u m i n am o u n t s u ffi
,

c ie n t t o for m a c re am y m i x t u re t h e n grad u all y add t h e

,

s i m ple elixir h av i ng pre v io u sl y d i s s ol v ed i n i t t h e m ag

,

n es i u m s u lph at e ; s t ir w ell an d fi l t er , .

Each fl u id drach m o f t h e fi n i s hed e lixir repre s e n t s sev e n

an d o n e h al f m i n i m s O f fl u id e x t ract o f rh u b arb an d
-

c o n t ai n s se v e n a d o n e h al f grai n s O f m ag n e s i u m s u l
n
-

ph at e .

I n t h e y ear 1 8 76 an an o n y m o u s corre spo n de n t fu r n i sh

ed t h e D m gg zlrts Ci rcul ar w i t h a m ix t u re fo r m aki ng t h e
’

abo v e e lixir I t w as m u ch m ore c o m plex an d pre se n t ed

.

n o ad v an tage s o v e r o u r for m u l a .

EL IXI R O F W ILD C H E R RY .

F l u i d E x t ra c t of W i l d C h erry 2 flu i d ou n ce s

S i m p l e El i x i r

C a rb on at e of M ag n es i u m , a s u ffi c i en t q u an t i t y .

Tri t u rat e th e fl u id ex t ract o f w i ld cherr y i n a cap a

c i o u s m or t ar w i t h carbo n at e o f m ag n es i u m i n am o u n t
,

su ffi c ie n t t o for m a c re am y m ix t u r e t h e n gr ad u all y ad d ,

t h e s i m ple e lixir st irri n g w e ll an d fil t er

, L ast l y m i x
, .
,

t h e fi l t r at e w i t h t h e al c ohol .

E ach fl u id d rac h m o f t h e fi n i s hed e lixi r w ill co n tai n

t h e m e di c i n al pri n c iple s O f se v e n an d o ne h al f grai n s o f -

w ild cherry b ark .

 58 E LI X IR F O RM U LIE .

E L I X I R O F C I M I C I F U GA .

( Eu xtR O F M A C RO T Y S .
)

F l u i d Ex t rac t of C i m i c i fu g a 2 flu i d ou n ce s

S i m p l e El i x i r
A l co h o l
C a r b on a t e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e fl u id ex t ract o f ci m i ci fu ga i n a cap aci o u s

m or tar w i t h car bo n at e o f m ag n e s i u m i n am o u n t s u hi
'

c ie n t t o for m a c re am y m ix t u re t h e n gr ad u all y ad d t h e ,

s i m ple elixir s t irri n w ell a n d fi l t er L t l m i t h

, g as , y x e .
,

fil t rat e w i t h t h e al cohol .

Each fl u id drach m o f t h e fi n i shed elixir sho u ld c o n tai n

s ev e n an d a h al f m i n i m s o f fl u id ex t rac t o f c i m i c i fu ga .

B u t as a m at t e r O f fac t t h at amo u n t w ill n o t di s s ol v e i n

, ,

t h at q u an t i t y o f t h e m e n s t r u u m t h e ex c e ss re m ai n i n g i n,

t h e fil t er p ap er Th e re m ark s w e m ake c o n cer n i n g elixir

.

o f gri n deli a rob u sta appl y w i t h eq u al per t i n e n ce t o t hi s .

CO M PO U N D EL IXI R O F C I M I C I F U G A .

( CO M UND
PO Eu xt R or M A C RO T YS . CO M UND
PO Eu x m or BL CKA C o u os u .
)
F l u i d E x t ra c t of C i m i c i fu g a 4 flui d ou n c e s

F l u i d E x t ra c t of W i l d C h e rry B a rk 2

F l u i d E x t ra c t of Li q u o ri c e 1

F l u i d E x t ra c t of S e n eg a 1

F l u i d E x t ra c t of I p e cac
S i m p l e El i x i r
C a rb o n a t e of M ag n es i u m ,
a s u ffi c i e n t q u an t i ty .

Mix fl u id e x t rac t s t og e t h e r an d ev aporat e t h e

th e
m ix t u r e t o t h r e e fl u id O u n c es Tri t u rat e t hi s i n a cap a
.

c io n s m or tar w i t h carbo n at e o f m ag n e s i u m i n am o u n t
,

s u ffi c ie n t t o for m a c r e am m ix t u re t h n gr ad all add

y e u y ,

t h e s i m pl e e lixi r s t irri n g w e ll an d fi l t e r
, ,
.

Each fl u id drach m o f t h e fi n i sh e d e lix i r r e pre se n t s

 E LI XI R F O R M U LZE .
59

bje c t t o re m ark s c o n c er n i n g e lixir o f c i m i c i fu ga ) fi f

( su

t ee n m i n i m s o f fl u id e x t r ac t o f c i m i c i fu g a t og e t h e r w i t h ,

s e v e n an d a h al f m i n i m s o f fl u id ex t r ac t O f w ild c herr y

b ark abou t fo u r m i n i m s e ach o f fl u id ex t rac t o f liq u ori ce

,

and se n eg a an d n e arl y t w o m i n i m s O f fl u id ex t rac t o f

,

i D ecac .

C LAU D E R S ELIX R
’
I .

C arb o n at e of P ot a s s i u m 1 t roy ou n c e

C h l o ri d e of A m m on i u m I

E l d e r - F l ow e r W at e r 1
% p i n t s

D i s sol v e an d add

A l oe s 1 t roy o u n c e

2 d ra c h m s

M acerate fo r e
t w n ty f -
o u r ho u r s ,
an d —
fil ter P icl crct
. .

E L I XI R O F C O C O .

F l u i d E x t ra c t of C oc o 2 flu i d ou n c e s

S i m pl e Elixi r
A l coh ol
C a rb o n a t e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e th e fl u id e x t rac t o f c o co i n a cap ac io u s m o r

tar w i t h carbo n at e o f m ag n e s i u m i n am o u n t s u ffi c ie n t t o
,

for m a c re am y m ix t u r e t he n grad u all y ad d t h e s i m ple

,

elixi r s t irri ng w ell an d fil t e r Las t l y m i x t h e fi l t rat e

, , .
,

w i t h t h e al c ohol .

Each fl u id drach m o f th e fi n i sh ed elixir repre se n t s

s e v e n an d o n e h al f m i n i m s o f fl u id e x t ract o f co co
-
.
60 ELI XI R F O R M U LIE .

EL I XI R O F C O L U M B O .

F l u i d Ex t rac t of C ol u m b o 2 flu id ou n c es

S i m p l e El i xi r
C arb o n at e of M ag n es i u m , a s u fl i c i en t q u an t i t y .

Tri t u rat e t h e fl u id e x t ract o f col um bo i n a cap ac io u s

m or tar w i t h carbo nat e o f m ag n e s i u m i n am o u n t su fl i ‘
‘

c ie n t t o for m a c r e am y m ix t u re t he n gr ad u all y ad d t h e ,

s i m ple elixir s t i rri ng w ell

,
an d fi l t e r ,
.

E ac h fl u id drach m O f t h e fi n i shed e lixir r e pr ese n t s

s e v e n an d a h al f m 1 n 1 m s o f fl u id ex t rac t o f c ol u m bo .

EL I XI R O F C O L U M B O , C I T R A T E O F I R O N A N D
RHU BARB .

(ELX I IR or CO LUM BO , I R N
O AND R HU R
BA B .
)

C i t rat e of I ro n t roy ou n c e s

S ol i d E x t r a c t of C ol u m b o
S o l i d E x t ra c t of R h u b arb
D i s t i l l ed W at e r 4 flu i d ou n c e s

B ra n d y 4
S i m p l e El i x i r 4

D i ss ol v e th e i t r at e O f i ro n i n th e di st i ll e d w at er and
c
'

t ri t u rat e t h e solid e x t ract s w i t h t h i s liq u id u n t il t h ey are

di ss ol v ed Fil ter th e sol u t io n an d m i x t h e fi l t rat e w i t h
.

t h e br an d y an d s i m ple e lixir .

Thi s m i x t u re w as gi v en t h ro u gh t h e D rugg zlrzs Ci rca ‘ ’

~

l ar 1 8 73 b y M r W T u rpi n S w e n ts ell
, ,
. . .
 EL I XI R F oR M U La . 61

CO M P O U N D E L I XI R O F C O R YD A L I S .

F l u i d E x t ra c t of C ory d al i s 1 fl u i d o u n c es
F l u i d E x t ra c t of S ti l l i n gi a
F l u i d E x t ra c t of F r i c k l ey A s h B e rri e s

F l u i d E x t ra c t of B l u e F l a g - R oo t
A l c oh ol
I od i d e of P ot a s s i u m g rai n s
S i m p l e E l i x i r , C a r b on a t e of M ag n es i u m , o f e ac h

a su fl i ci en t q u an t i ty .

Tri t u rat e t h e m ixed fl u id ex t rac ts i n a cap acio u s m o r

t ar w i t h carbo n at e o f m ag n e s i u m i n am o u n t su ffi c ie n t
,

t o for m a c r eam y m ix t u re t h e n gr ad u all y ad d si m pl e ,

elixi r e n o u gh t o prod u c e fo u rt e en fl u id o u n ces st irri n g ,

w e ll an d fil t er
,
Last l y m i x t h e fil t rat e w i t h t h e al cohol
.
, ,

and di s s ol v e t h e iodide o f po tass i u m i n t h e liq u id .

E ach fl u id drach m o f t h e fi ni s hed e lixi r repr ese n t s th e

propor t io n w h i ch t h e m e n st r u u m w ill di ssol v e o f abo u t
fo u r m i n i m s e ac h o f fl u id ex t ract o f c or y d ali s an d o f
s t illi n gi a abo u t t w o m i n i m s o f fl u id e x t rac t o f i c k l ey
, p r

as h berrie s an d s i x m i n i m s o f fl u id ex t rac t O f bl u e fl ag
,

roo t ; t oge t her w i t h t w o grai n s o f iodide o f po tass i u m .

We h av e li tt le fai t h i n t h e po w er o f t h e abo v e m e n s
t ru u m t o diss ol v e t h e de s ir able pri n c iple s O f t h e dr u g s ,

c or y d ali s perh ap s ex c ep t ed ; b u t t h e elixir m ay be t h e r

, ,

ap e u t i call y w or th y s i n ce iodide o f po tass i u m alo n e i s v al

,

u ab l e .

The bo v e form u l a i s n earl y ide n t i cal w i t h t h at O ffe re d

a

b y t h e j oi n t co m m i t t ee O f t h e N at io nal C ollege O f Ph ar
m acy an d t h e M edi cal S o cie ty o f t h e D i st ri ct o f C ol u m
,

b ia .
62 EL I XIR F O R M U LA"
“

EL I XI R O F C O T O .

F l u i d E x t r ac t of C ot o 2 fluid ou n c es

S i m p l e El i x i r 1 6
C a rb o n a t e of M ag n es i u m , a s u ffi c i en t q u an t i ty .

Tri t u rat e t h e fl u id ex t ract o f co t o w i t h m ag n e s i u m car

bo n at e u n ti l a crea m y m ix t u r e re s u l ts t he n grad u all y
, ,

ad d t h e s i m ple elixir an d fil t er Each fl u id drach m o f

, .

t hi s elixir repre se n t s s u ch an am o u n t o f se v e n an d a h al f
grai ns O f co to as w ill di ssol v e i n t h e liq u id .

E L I XI R O F C H L O R O F O R M .

( CH L R F RM
O O O PA RE R C
GO I or D R . H A R r su O R N B )
'
.

C h l oroform flu i d ou n c es

T i n c t u re of O pi u m 1
%
T i n c t u r e of C a m p h or
A rom at i c S p i ri t of A m m on i a
B e s t B ra n d y 2

M i x t oge t her .

Each fl u id drach m o f th e fi n i shed elixi r co ntai n s ele v e n

an d o n e fo u r t h m i n i m s o f e ach o f t h e m edi c i n al i n gre
-

d i en t s . I t sho u ld be di s p en sed cau t io u s l y .

Th i s prep arat i o n w as origi nall y u s ed u nder t h e nam e

c hloro for m paregori c o f D r H ar t shor n e an d t h e for m
.
,

u l a w as p u bli s hed i n t h e book o f for m u l a i ssu ed i n 1 8 6 7 , ,

b y t h e j oi n t c o m m i t t ee o f t h e M ed i cal an d Pharm ace u t i

cal A sso c ia t io n s o f t h e D i st ri ct o f C ol um bia .
 ELI XIR F O R M U LZE . 63

EL I XI R C H LO RO F O R M I Q U E O F B O U C H U T .

( B o uc u v r
'
’
s E LXR
I I OF C HL R F RM )
O O O .

M i x i n th e order gi v e n .

E ach fl u id drach m o f th e fi n i shed elixir co n tai n s o ne

an d th ree fi ft h s o f a m i n i m O f chloro for m

-
.

( P r oc ee d i n g s o f A m e r i c an P h a r m ac e u t i c al A s soc i at i o n ,

EL I XI R O F C R O TO N C H L O RA L HY D RATE .

C rot on C h l oral H y d rat e 1 28 g ra i n s

D i s t i l l ed W at er 2 flui d ou n c e s

S i m pl e El i xi r

D i ssol v e ro t o n chloral h y drat e i n th e w at er an d

th e c ,

add t h e s i m pl e elixir
( D i C E ’
ru
gg sts. i r cu l ar a c h ’

fl u id drach m ( t easp oo n fu l ) Of t h e fi n i shed elixir c o n tai n s

°

o n e grai n o f c ro t o n c hlor al h y dr at e .
64 ELI XIR F O R M U L/E .

E L I X I RS O F CA L I SAY A O R CI NC H O N A B A RK
A ND TH E A L K A LO I D S .

The se i ncl u de t h e m o st pop u l ar e lixir s an d w h i ch are ,

pre s cribed m o st fre e l y b y ph y si ci an s T h e origi nal co r

.

d i al e lixir o f cal i say a co n tai n ed all O f t h e pri nc iple s o f

,

t h e b ark w hi ch w ere s ol u bl e i n t h e m e n st r u u m u s ed i n
m aki n g i t an d as a s i m pl e e lixir o f cali say a i s pre ferred
, ,

b y m any ph y s i ci an s at t h e pr e se n t d ay Whe n co m b i n
.

at i o n s o f cali say a b ark an d t h e v ario u s iro n pr e p ar at io n s

w ere i n t rod u ce d a d e m an d w as c r eat ed fo r an elixir o f

,

cali say a w hi ch c o u ld be m ixed w i t h c er tai n iro n sal t s

w i t ho u t pre c ipi t at io n or i n k y di sc olorat io n an d t h i s w as

, ,

“
follo w ed b y t h e i n t rod u c t io n o f d e t an n at ed e li xir Of
cali say a , w h i c h w o u ld an s w e r t hi s p u rpo se H o w ev er .
,

i n m aki n g t h e d e tannat e d elixir t h e n at u ral c o mbi n at io n

,

O f t h e alk aloid s i s de s t ro e d a n d t h e c i n c ho t an n i c ac id
y
-
,

i s sep arat ed an d w e pr e fer t o u se t h e alk aloid s O f cali say a

,
-

dire c t The u se o f t h e alk aloid s b y ph ar m ac i st s i n

.
, ,

s t e ad o f t h e b ark , w ill ce r tai n l y gi v e a m or e defi n i t e

prep arat io n as v ari at io n i n q uali ty i s t h u s o v erc o m e an d
, ,

“
w e do n o t k no w th at t h e nam e elixir of cali say a i s
v er y i n appropri at e u n d e r t h e s e c o n di t io n s H e nce i t i s
.
,

“
t h at w e d ire ct t h e elixir o f cali saya fro m t h e alk aloid s ”

i n t h i s w o rk ; b u t i f t h e operat or pre fer s t h e d et annat ed ,

elixir can b e su b st i t u t ed .

I t m u s t be r e m e m bered t h at th e alk aloid s o f cali say a

,

are al m o s t i n s ol u bl e i n a s ligh t l y alk ali n e or n e u t r al aq u e

66 E LI X IR F O R M U LA;

c lo s e l y t o th e p ap e r I n Order t o o v erc o m e t h e se t ro u ble s

.
,

t h e w ri t e r h as d e v i sed t h e follo w i ng pro ce s s w h i c h y ield s ,

an alk aloid w hi c h ans w er s e v e r y p u rpo s e req u ired b t h

y e

c l ass of pr e p ar at io n s u n d e r c o n s id e r at i o n :

A LK ALO I D Q U I N I N E O R A LK A LO I D C I NC HO NI D I N E .

S u l p h ate of
Q ui n ne
i or S u l p h ate of C i n ch o n i
d i ne o u n ce

W at e r
D i sti l l ed 3 2 fl uid o u n ce s

A m m o n i a W ater

Mix t h e am m o n i a w at er w i t h t h e
di st ill e d w at er an d ,

h av i ng pl aced th e s u lph at e o f t h e de s ired alk aloid i n a

m or tar grad u all y t ri t u rat e i t w i t h a s u ffi c ie n t am o u n t o f
,

t h e liq u id so as t o for m a t hi n cr e am y m ix t u re t he n
, , ,

ad d t h e re m ai n d e r o f t h e m ixed w at ers Per m i t t hi s t o .

s t an d h al f an ho u r an d t ran s fe r t o a fi l t er p aper ; t he n
, ,

aft er t h e pr e c ipi tat e h as dra i n e d r e t u rn i t t o t h e m or tar , ,

an d m i x i t ag ai n w i t h a liq u id c o m po sed o f

W ater
D i sti l l e d 32 fl u id o u n ces

A mm o n i a W ater

P e r m i t t hi s m ix t u re to stan d fo r h al f an ho u r an d t h e n ,

t ran sfe r i t t o a m u s li n s t ra i n e r s q u e e z e i t u n t il t h e liq u id

,

i s expre s s e d an d t he n d ry i t b y h angi ng i t i n t h e at m o s
,

p h e re w,
i t ho u t ho w e v er re m ,
o v i n g t h e s t r ai n er
,
.

T h e for egoi n g pro ce ss o ffe r s sev e ral ad v an t age s o v er

t h e O l d n o t t h e l e ast b e i n g t h e r e ad y prod u c t io n o f an al
,

ka l o i d i n a poro u s an d fi n e l y di v id e d for m I f t h e st rai n e r .

i s p e r m i t t ed t o r e m ai n d u ri ng t h e pro c e ss o f dr y i n g t h e ,

liq u id carrie s t h e di s sol v ed s u lph at e o f am m o n i u m t o t h e

s u r face as i t e v aporat e s an d depo s i t s i t u po n t h e m u s li n " .
, ,

T h is p
ro c e ss i s o t en f f
o l l o w e d b y t h e w r i t e r w i t h r e g ar d t o o t h e r r e c i i t at e s p p
w h i c h c o n t ai n c ol o r i n g p
m a t t e r s an d i m u r i t i e s , t ha t o r d i n a r y w as h i n g s e e m s n o t t o
p
s e ar a t e p g p p
B s r e ad i n t h e m i n t h i n l ay e r s u o n m u s l i n an d r e s s i n a s h e e t o f m u s
y g
p i f p q
.

l i n u o n t h e r s u r ac e , t h e i m u r i t i e s ar e c ar r i e d b y t h e l i u i d t o t h e s u r fac e .
 ELI XIR F O R M U LIE . 67

E L I X I R O F C A L I S A YA O R C I N C H O N A .

( Go R m A t . m xR O F C A Lt S A v A . Eu x tR o r B RK )
A .

C al i s ay a B a rk . 4 t roy ou n c es

F re s h O ra n g e P e e l . r 2

C ey l o n C i n n a m on 1

C ori a n d er S e ed
F e n n e l S e ed
C araw ay S e e d
C a rd am o n S e ed
C oc h i n e al
B ra n d y 40 flu i d ou n c e s

A l coh ol 1 6
W at e r 56
S i m p l e S y ru p 40

Red u ce t h e orange peel p u lp b y co n c u ss io n i n an

to a ,

iro n m or tar an d m i x t h e p u lp w i t h t h e re m ai n der O f

,

t h e dr u gs h av i n g pre v io u s l y red u ced t he m t o a c o ar s e

,

po w d e r M i x t h e bran d y al cohol and w at er an d m oi s t e n

.
, ,

t h e po w der w i t h an am o u n t s u ffi cie n t o f t hi s m e n s t r u u m
t o prep are i t fo r per c ol a t io n Pack t h e m oi st e ne d po w der
.

i n a su i table per c ol at or an d e x t ract i t b y p e r c ol at io n

,

w i t h t h e r e m ai n der o f t h e m en s t r u u m Last l y m i x t hi s .
,

p e r col ate w i t h t h e s i m ple sy r u p .

Thi s for m u l a w as fu r n i sh e d t h e A meri can j ournal of

P /z ar macy Jan ,
1 8 59 b y M r A l fred B Tay lor ex cep t
.
, , . .
,

i ng t h at t h e m an ip u l at io n h as b e e n s ligh t l y m odifi e d by
us . Th i s pro ce ss fu r n i sh es a v e ry p al atable prep arat io n ,

an d at o n e t i m e i t w as pop u l a r u n der t h e nam e c ordi al

elixi r o f cali say a H o w ev er a sligh t pr ecipi tate o ccu r s

.
,

i n i t aft er stan di n g an d as a r u le ph ar m aci st s pre fer an

, ,

elixi r m ad e o f t h e alk aloid s I n o u r opi n io n t hi s e lixir i s

.

O ft e n t h e pre fe r abl e e lixir o f cali say a b u t o u t o f re s pe ct ,

t o th e de m an d s o f t r ad e an d c o m bi n at io n s t o be m ade
, ,

w e s h all re cog n i z e u n d e r c o m po u n d s o f cali say a an el xir

i ,

made w i t h ci ncho na alk aloid s as follo w s ,

68 ELI XI R F O R M U LzE .

E L I X I R O F C A L I S A YA A L K A L O I D S .

( Eu x t n o r CA L Y
IS A A. Eu xtR O F CI NCH N B RK
O A A . LXR
E I I O F B RK )
A

S i m pl e El i xi r 16 flu i d ou n ce s

Qu i n i n e ( A l k al o i d ) 12 g ra i n s
C i n c h on i n e ( A l k al o i d ) 6

Mix th ealkaloid s an d t ri t u rat e t he m i n a m ortar w i t h

,

o n e fl u id o u n ce o f s i m ple e lixir and t he n grad u all a dd

y ,

ace t i c ac id i n am o u n t s u ffi c ie n t t o e ffe ct t heir s ol u t io n ;

t he n ad d t h e re m ai nder O f t h e s i m p l e elixir Each fl u id .

drac h m ( tea spoo nfu l ) o f t h e fi n i s hed elixir co n tai n s alk a ,

loid s su fli ci ent t o repre s e n t fo u r grai ns o f O ffi ci nal cali say a

bark The prep arat io n i s t h at adop t ed by t h e A m eri can
.

Ph ar mac e u t i cal A sso ci at io n 1 8 75 The elixir h as a d i s , .

t i n c t bi t t er tast e an d w e h av e re as o n t o belie v e t h at an y
, ,

s u b s t anc e w h i ch w ill o v er c o m e t h e bi t t er n e ss w ill do s o ,

at t h e e xpe n s e o f t h e alk aloid s re nderi ng t he m i n so l u ,

ble V ari o u s plan s h av e bee n re co mm e nded fro m t i m e

.

t o t i m e fo r d et annat i n g cali say a b ark u s u all y b y m e an s

, ,

o f h y droxide o f iro n fi r s t s u gge st ed b y M r f M eier O f

, ,

N e w Y ork i n 1 8 67 ,
Th ese pro ce sse s are t edio u s and
.
,

t h e prod u ct pre se n t s li tt le i f an y ad v an tage s o v er a si m

, ,

ple s ol u t io n o f t h e alk aloid s For t hi s re aso n w e co n .

“
s ider t hi s for m u l a a pr ac t i cal s u b st i t u t e for d e tannat e d
elixir o f cali saya w hi ch follo w s
,
”
.
 ELI XIR F O R M U L ZE . 69

D ET A N N AT E D E L I X I R O F C A L I S A YA B A R K .

(D ET A N N A T E D Eu x tR o r Ct uO NA B RKA . D ET A N N A T E D Eu xta O F B RK )
A

C al i s ay a B a rk 24 t roy ou n c es

C u ra c oa O ra n g e P eel 1 6

4
1
%
C ey l on C i n n a m on
A n i se
Bak er
’
C oc oa ( S ) 8

Red u ce t o a m od e r at el y fi n e
po w der ; di spl ace w i t h a
m ix t u re c o n s i s t i ng o f o n e p ar t b y m e asu re o f al cohol , , ,

an d t hr ee p ar t s o f w at er u n t i l t w o an d a h al f g allo n s o f
,

p e rc ol at e are ob tai ned .

M e an w hile p rep are h y drat ed s e s q u ioxide O f i ro n fro m

, ,

s i x pi n t s o f s ol u t io n o f t e r su lph at e o f iro n acc ordi n g t o ,

t h e ph ar m ac op oei al pro ce s s m easu re i t an d ad d t o , ,

e v e ry fo u r m e asu re s o n e m e as u re o f al cohol ; t he n ad d
,

o f t hi s s u fli ci e n t t o t h e per col at e ob tai n ed as abo v e to ,

depri v e i t o f i t s ci ncho tann i c aci d The ab se n ce o f t h e

-
.

l att er i s re adil y ascer tai ned b y t h e addi t io n o f a drop o f

t i nc t u re o f c h l oride o f iro n t o a fi l t ered por t io n O f t h e,

liq u id i n operat io n w h i c h s h o u ld n o t be colored by s u c h

,

addi t io n S ho ul d c olorat io n re s u l t t h e i n t e n s i ty or fai n t

.
,

n e ss w ill s er v e as a g u id e t o t h e fu r t her q u an t i t y o f h y

d rat ed se squ ioxide o f iro n n e ce ssary t o c o m ple t el y de

t an n at e t h e prep arat io n A s s oo n as t hi s re s u l t i s o h
.

t ai n e d st rai n t h e m i x t u re u po n a m u s li n s t rai ne r an d
, ,

w h e n t h e liq u id ce ase s t o p as s w as h t h e re s id u e u po n t h e ,

s t r ai n er w i t h s u ffi c ie n t o f a m ix t u r e o f o n e m e as u r e o f
,

a l c oho l t o t hree o f w at er t o m ake t h e s t rai n ed liq u id

,

m eas u re fi v e g allo ns N o w t ri t u rat e t oge t her O i l o f

.
,

o ran ge o n e h al f fl u id o u n c e
-
carbo nat e o f m ag n es i u m ,

fo u r t ro y o u n ce s Whe n t h oro u ghl y m i xed i n corporat e

.
,

i t w i t h t h e st r ai n ed li q u id ob t ai n ed as abo v e agi tat e w ell , ,

7o ELI XIR F O R M U LZE .

an d p aper ; expre ss t h e fil ter be t w ee n m u s

fi l te r t h ro u gh
l i n fi l te r t h e expre ssed l iq u id an d m i x w i t h t h e pre v io u s
, ,

fi l t rat e i n w hi c h di ssol v e fi ft ee n p o u n d s av oird u poi s o f

,
'

s u gar I f n e ce ssar y fi l t er t h e e li xir t h u s O b tai ne d ; b u t

.
,

s i m pl e st rai n i ng w ill u su all y an s w er .

Th e abo v e for m u l a i s t h at o f Pro f C L e w i s D i e hl as . .

,

pre se nted t o t h e L o u i sv ille C ollege o f Phar m acy Jan , .

1 6, 1 8 72 .

E ach fl u id drach m ( t eas poo n fu l ) o f t h e fi n i s h e d e li xir ,

r e pre se nt s abo ut t w o grai n s o f cali say a bark o f t h e q ual

i t y e m plo y ed b y t h e op e r at or .

The fi r st re cord w e can fi n d o f d etan n at i ng the perc o

la t e fro m cali saya bark b y m eans o f h y drate d s e sq u i
,

o xide o f iro n fo r t h e p u rpo se o f m aki ng an e lixir w as

, ,

t h e c o m m u n i cat io n t o t h e D r ugg zlrts Ci r cu l ar 1 8 6 7 b y

’

, ,

M r M eier o f N e w Y ork
.
,
H e u sed s ol u t io n o f fe rri c
.

c hloride t o prep are t h e h y droxide D etannat ed e lixir o f

.

cali say a w as i n t rod u ce d t o s u ppl y a s ol u t io n o f t h e al k a

loid s o f cali say a w h i ch c o u ld be m ixed w i t h iro n sal ts

,

w i t ho u t pre cipi t at io n or i n k y di s colora t io n W e are s u re .

t h at ph ar m ac i s t s ge n e rall y w ill m ee t w i t h be t t er s u cc ess

, ,

r egard i ng t h e q u ali ty o f t h e prod u ct by u s i n g an e lixir ,

dire ct l y fro m t h e alk aloid s ; he nce w e fav or t h at for m o f ,

e lixir o f cali say a i n t hi s w ork We can n o t say t h at '

t her e i s ac t u all y m u ch di ffere n ce i n t h e fi n i sh e d pr e p ara

t io n s i nce t h e n at u r al c o m bi nat i o n o f t h e alk aloid s i s

,

brok e n w h en t h e c i n ch o t an n i c acid i s re m o v ed an d all

-
,

m u s t ad m i t t h at th e cali say a b ark s o f c o m m e r c e are u n

c er t ai n i n q u ali ty The elixir o f t h e alk aloid s i s o f d efi
.

n i t e s t re ng t h .
 EL I XIR F O R M U L zE .
71

D E S L A U R I E R S E L I X I R O F C A L I S A YA A N D CO F F EE
’
.

Y el l o w C i n c h o n a B a rk 2
% t roy ou n ces

B row n C i n c h o n a B a rk 1

B row n e d ( sl i g h tl y ) C offee
S u g ar
S h er ry W ine 32 flu i d ou n c es

C i t ri c A c i d 1 50 g rai n s

R ed u c e t h e dr u g s t o a co ar se po w d e r and m i x al l th e ,

abo v e n am ed i n gredie n t s A llo w t h e m ix t u r e t o m acer

.

at e fo r a fe w d ay s i n a w ar m lo cat io n t h e n bri n g i t t o a ,

boil c ool an d fil t er i t D i ssol v e i n t h e fi l t rat e t en and

, ,
.

o n e h al f o u n ce s o f s u gar
-
and ad d t w o fl u id o u n ce s of ,

“
al c ohol T h e abo v e i s tak e n fro m
. N ew Re m edie s ,

1 8 78 an d i s k n o w n as elixir de s l au ri e r s t o n i febri fu ge au
.
-

q u i n q u i na et cafe .

E L I X I R O F C A L I S A YA W I TH L A C T O - P H O S P HAT E O F
LIM E .

( Eu x ut o r C 1 N C 11 0N A w rr u L A CT O -PH H TE OSP A or LI ME . E LXR

I I or LA c r o - P u o s "

PHA I E O F
' ‘

CA LC UM w m
I r CA L Y
IS A A .
)

El i xi r of C a l i s ay a ( A l k al oi d al 8 fluid ou n c e s

El i x i r of L a ct o- P h os p h at e of C al ci u m 8

Mix h e m t og e t h e r
t .

E ach fl u id drach m ( t e aspoo n fu l ) O f t h e fi n i sh e d elixir ,

c o n t ai n s o n e hal f grai n o f la ct o pho sph at e of cal ci u m

- -
,

an d repre s e nt s t w o grai n s o f cali say a .

72 E LI XIR F O R M U LfE .

E L I X I R O F C A L I S A YA A N D C H LO RI D E O F I RO N W I TH
AM M O N I U M C I TRAT E .

(E LXR
I I or C A Lt S A v A AND C H R DE
LO I or R N
I O . Bu xi a O R Ct uox A A ND C HL O

R DE I or IR N ) O .

El i x i r of C al i s ay a 1 5 flu id ou n c es

S ol u t i o n of C i t rat e of A m m on i u m
T i n ct u re of C h l ori d e of I ron
M i x th e s ol u t io n Of c i t rate of a mm o n i u m w i t h t h e t nci
t u re hloride o f iro n and ad d th e eli xir o f cali say a
of c , .

Each fl u id drach m ( t e as poo nfu l ) o f t h e fi n i shed e li xi r

c o n t ai ns abo u t t w o m i n i m s o f t i n ct u re o f c hloride o f i ro n ,

and repre se nt s n e arl y fo u r grai n s o f cali say a The ad di .

t io n o f t h e s ol u t io n o f c i t rat e o f am m o n i u m pre v e n t s

d i scol o ra t io n o f m ix t u re s o f t hi s elixi r an d s u b stan ce s ,

c o n tai ni ng v ege table t annat es To t h e fact th at t hi s m i x .

t u re co u ld a ccom pli sh t h e afore nam ed re s u l t w e are i n ,

d eb t e d t o M r J C re u se w h o h as w ri t t e n se v eral i n t er
. .
,

es t i n g ar t i cle s o n t h e s u bj e ct an d w e re fer t h e r eader t o ,

t h e b ack n u m bers o f t h e D r uggt kts Ci rcul ar an d j our nal

’

P h r m i f p r i l rl i ere ed i h b
of a a cy a t ,c u a y n t st n t e s u j e c t .

E L I X I R O F C A L I S A YA , C I T R A T E O F I R O N A N D B E EF .

( Eu x tR or CA L Y
ISA A, I R N
O A ND B EEF . Eu x t a or CI NC H N O A, I R ON A ND B e ar .
)

El i xi r of B ee f w i t h C i t rat e of I ron 8 flui d ou n c es

El i x i r of C al i s ay a ( A lk al o id al ) 8

M i x t he m t oge t her .

E ach fl u id dra ch m ( t eas poo nfu l) of th e fi ni s hed elixi r ,

c o n tai n s o ne grai n o f ex t ract o f bee f o ne h al f gr ai n o f ,

-

c i t rat e o f iro n an d repre s e n t s t w o grai n s o f o ffi ci nal cali

,

s ay a .

The re mark s co ncer n i n g e lixi r o f bee f and c i t rat e of

i ro n m ay be appl i ed t o t hi s prep arat io n .

74 EL I X IR F O R M U LIE .

Eac h fl u id d rach m ( t easpoo n fu l ) o f th e fi n i shed el ix ir ;

c o n t ai n s o ne grai n o f e x t rac t o f bee f o n e h al f gr ai n O f ,
-

c i t rat e o f iro n O ne fi ft i e t h grai n o f st r y c h n i n e an d re re

p
-
, ,

s e n ts t w o gr ai n s o f cali s ay a I t i s n o t a per m ane n t .

prep arat io n fo r e xpl anat io n of w hi ch asser t io n see o u r

,

re m ark s o n elixir o f bee f w i t h c i t r at e o f iro n .

EL IXI R O F CALISA YA B ARK W I TH C I T R A T E O F P R O

T OX ID E O F I RO N .

(E LXR
I I or CA L Y IS A A AND P RO T O X t D a or R N I O . LXR
E I I or L Y B RK
CA IS A A A A ND

F ER R U O S CI T R TE A . E LXR
I I OF C NCH N
I O A A ND P RO T X DE I R N )
O I OF O .

S u l p h at e I ro n , C ry s t al l i z
of ed

B i c a rb o n at e of S od i u m
C i t ri c A ci d , D i s t i l l e d W at er , El i x i r of C al i s ay a B a rk ( Al
k al o i d al ) , o f e a c h a s u fl i c i en t q u a n t i ty .

D i s sol v e lph at e o f iro n an d t h e bi carbo nat e o f

th e su

s odi u m s ep ar at el y
,
e ach i n s ix t ee n fl u id o u n ce s o f cold
, ,

fre shl y di st ill e d w at er an d m i x t h e s ol u t io n s Po u r t h e

,
.

m ix t u r e s i n t o a bo tt le w h i ch m u st b e fill e d t o t h e st op ,

per u si ng m ore di st illed w at e r i f n e ce ssary an d per m i t

, ,

i t t o re st fo r t w e n t y fo u r ho u r s D e cant t h e c lear s ol u
-
.

t io n an d r e fill t h e bo t t le w i t h fre s h l y di s t illed w at er

, ,

s h aki n g w e ll an d p e r m i t i t t o s t an d as be fore
,
A ft e r .

t w e n t y fo u r ho u r s de can t t h e c le ar s ol u t io n
-
po u r th e ,

re sid u e u po n a fi n e m u sli n s t rai n er and s q u eeze t h e .

,

liq u id fro m i t D i ss ol v e t h e pre cipi tat e b y t ri t u rat io n i n

.

a m or t ar w i t h c i t ri c ac id i n s uffi c i e n t am o u n t an d t he n
, ,

ad d e n o u gh e lixir o f cal i s :1 y a b ark t o m ake s ix t ee n fl u id

o u n ces ; an d fi l t e r .

E ach fl u id drac h m ( t easpoo nfu l ) o f t h e fi n i s hed elixi r ,

c o n t ai n s o f c i t rat e o f pro t ox i d e o f iro n an am o u n t w hi c h

i s eq u i v ale n t t o t w o grai n s o f c ry st allized su lph at e O f iro n ,

and i t re p re se nt s ab o ut t hree grai ns o f cali say a ba rk .

 E LI X IR F O R M U L zE .
75

n am e
The ( elixi r o f pro t oxid e o f iro n
) i s a m i s n o m er
“

i f ap p l i ed t o a prep arat io n lik e t hi s an d al l t h e pro ce ss e s ,

w e h av e s ee n gi v e a sol u t io n o f a sa l t o f pro t oxide o f

iro n Thi s fact h as bee n rep eate dl y n o t i ce d i n t h e D rug
.
‘

C l r an d o t h er j o u r nal s an d s u c h au t hori t i e s as
’

g
‘

zlrts i rcu a ,

M r C re u se Pro f D iehl an d Pro f O l d be rg hav e called

.
, . .
,

p ar t i c u l ar att e nt io n t o t h e m i sn o m er N o t w i t h stan di n g .

al l o f w hi c h w e fi n d ph y s i c i an s an d e v e n ph ar m ac i s t s
, , ,

i n s i st o n u si n g t h e t er m an d w e t here fore pl ace i t a m o ng

,

o u r sy n o n y m s .

E L I X I R O F C A L I S A YA B A R K W I TH C IT R A T E O F P RO
T O X I D E O F IRO N A N D ST R YC H N I N E .

(E LXR
I I or R T X DE I R N
C A Lt S A v A , P O O I OF O A ND S T RYCH N EL X R B RK
IA . I I or A ,

P Ror o x m n or IR ONS T RYC H N

AND E IA . u x1R O F C L Y FE R R U A IS A A, O S

CI T R TE
A S T RYCHN
A ND EL X R IA . I I OF CI NCH N O A A ND

C TR TE I PR T X DE
A or O O I OF IR N )
O .

El i x i r of C al i s ay a w i t h C i t rat e of P rot ox i d e of

I ron 1 6 flui d ou n ce s

S t ry c h n i n e 2
% g rai n s
A c et i c A c i d , a s u ffi c i e n t q u a n t i ty .

Tri t u r at e t h e s t ry ch i ne i n a m ortar cau t io u sl y addi ng ,

acet i c ac id u n t i l i t i s di ssol v ed t he n m i x w i t h t h e elixir ,

o f cali s ay a an d c i t r at e o f pro t oxide o f i ro n .

Eac h fl u id drach m ( t e aspoo n fu l ) o f t h e fi n i shed elixi r ,

c o n tai n s O f c i t r at e o f pro t oxid e o f iro n an am o u n t w hi c h

i s eq u i v ale n t t o t w o grai n s O f s u lph at e o f iro n an d o n e ,

fi ft i et h grai n o f s t ry c h n i n e an d r epr e se n t s abo u t t hree ,

gr ai ns o f cali say a b ark Thi s prep arat io n i s u nstable . .

 6 E LI XIR F O R M U LzE .

E L I XI R O F C A LI S A YA B ARK W I TH P YR O P H O S P H A T E
O F I RO N .

( Eu xtR O F B K w m P YR H
C 1NC HO N A AR r OP H TE
OSP A OR I R N
O . EL1 x 1 R OF CA L Y
IS A A

B RK IA N EL X R
AND RO . I I or B R A R AND IR N
O . FER
R T E D EL X R A I I OF C A Lt S A V A .
)

El i x i r of C al i s ay a ( A l k al o id al ) 1 4 flui d ou n c e s

D i s t i l l ed W at er 2

P y rop h os p h at e of I ro n g r a i n s

D i ssol v e p y ropho s ph at e o f iro n i n t h e d i s t illed

the
w at e r ad d t h e elixir o f cali say a and fil t e r i f n e ce ssary
, , ,
.

I f n o t n e u t ral i n re act io n bri n g i t t o a n e u t ral c o n di t io n

,

by addi t io n o f e i t her ac e t i c ac id or am m o n i a w at er .

E ach fl u id drach m ( t ea spoo n fu l) o f th e fi n i sh ed el i xir

c o n t ai n s t w o gr ai ns o f p y ropho spha t e o f iro n an d r e p re ,

s e n t s abo u t fo u r gr ai n s o f o ffi ci n al cali say a b ark The .

ropor t io n i s t h at r e co m m e n ded b t h A m er i an Ph ar
p y e c

m ace u t i cal A sso ci at io n 1 8 75 , .

I n 1 8 6 2 M r J am e s T S hi nn p u bli shed ( Ameri can

,
. .

j o u rnal o f Ph a r macy
) a pro c e s s fo r m aki n g th e abo v e

elixir e m plo y i ng c r u de m at eri al s u po n th e pri nc iple o f

,

M r Tay lor s el i xir o f cali say a I n s pe aki n g o f i t M r

’
. .
. ,

S hi n n u se s t h e follo w i ng l an g u age : A m o n g t h e ph ar
m ace u t i cal n o v el t ie s r e ce nt l y bro u gh t t o t h e n o t i c e o f
ph y s i c i an s t hi s prep arat io n o f i ro n c i n cho n a an d bran d y
, ,

i s o n e o f t h e m o st agree able an d po ss ibl y m ay pro v e

v ery pop u l ar w i t h p at ie nt s The re s u l t pro v e s M r . .

S h i nn s s u r m i se t o h av e bee n corre ct al t ho u gh t h e origi

’

6
n al pr e p arat io n s h av e bee n repl ac ed w i t h t h ose m or e .

ple asi ng t o th e ey e .
 ELI XI R FO R M U LAt .
77

EL I XI R O F CALISA YA B ARK W I TH P YR O P H O S P HA T E
O F I RO N A N D C I TRATE O F AM M O N
IUM AND B ISM U TH .

( EL1x 1 R or CA L Y IR N
IS A A, O AND B M UTH IS . E L X R C NCH N I R N
I I OF I O A, O AND 3 15

MU T H " . t. 1 l O F B RK I R
A , ON A ND B M U T H FE R R T E D
IS . A

Eu x m B RK
or A AND Bi sM U r u ) '
.

A m m on i o- C i t rat e of B i sm u th 1 28 g rai n s
D i s t i l l ed W at e r 2 flu i d ou n c e s

El i x i r of C al i s ay a B ark w i t h I ron , a s u ffi c i e n t q u an
t i ty .

D i ss ol v e t h e am m o n io ci t ra t e -
of b i sm u t h i n th e d i s
t i lled w at er , cau t io us l y addi ng am m o n i a w a t er i f nec es
sary ; t he n aelixi r o f cali say a b ark w i t h iro n su ffi cie n t
d d ,

t o m ake s ix t ee n fl u id o u n ce s S ho u ld a pre cipi tate fo l .

l o w t h e addi t io n o f ei t h e r am m o n i a w ater or ace t i c ac id

, ,

as t h e cas e m ay de m an d t o re n der t h e liq u i d n e u t ral , ,

w ill redi s sol v e i t .

Each fl u id drach m ( t e aspoo nfu l) o f th e fi n i shed el i xi r

c o n t ai n s o n e gr ai n o f amm o n i o c i t r at e o f bi s m u t h abo u t -
,

t w o grai n s o f p y ropho s ph at e o f iro n an d re re s e n ts

p ,

n e arl y fo u r grai n s o f o ffi ci n al cali say a b ark .

E L I X I R O F C A L I S A YA B A R K , W I TH P YR O P HO S P HATE
O F I R O N , C I T RA T E O F A M M O N I U M A N D B IS
M U TH , A N D S T RYC H N I N E .

( EL1 x 1 R OF L Y CA IS A A, I R N ST RY C HN
O , IA AND MU T H EL R
BI S C NCH N . IX I or I O A,
I O R N S T RYCHN
, IA A ND B M UTH E IS . u x xR O F B R K I R N S T RYCHNA , O , IA A ND

B M UT H
IS F . E R RA I ED
' ‘
Eu xtR o r B R SA K, m e
'
B M U TH )
cn A A ND IS .

El i x i r of C a l i s ay a B ark w i t h P e p h O S p h at e of I ron ,
C i t r a t e of A m m o n i u m a n d B i s m u t h 1 6 flu i d ou n c e s

A c e t i c A ci d , a s u ffi c i e n t q u an t i ty .

Po w de r t h e s t ry ch n i n e an d di ss ol v e i t i n a su ffi c ie nt
am o u n t o f ac e t i c ac id an d m i x t h i s w i t h t h e elixir , .

Each fl u id drach m ( t e as poo nfu l) o f t h e fi n i shed e l ix i r

78 ELI XI R F O R M U LIE .

c o n tai n s o n e grai n o f am m o n io ci t rat e o f bi sm u t h abo u t -

,

t w o gr ai n s o f p y ropho s ph at e o f iro n and o n e fi ft i et h o f ,

-

a gr ai n o f st r y c h n i n e and repre se nt s n earl y fo u r grai ns o f

,

o ffi ci n al cali say a b ark .

E LI X I R O F C A L I S A Y A W I T H P YRO P H O S P H AT E OF
IRO N AN D LAC TO - P H O S P HATE O F C ALC I U M .

( Bu xu or CA L Y
IS A A, R N
I O AND LA CT P H H T E
O- OSP A or Lm n . Eu x xR o r C 1N
CH N O A, IR N O AND L CT P H
A H TE
O- O SP A OF Luna ) .

El i x i r of C al i s ay a w i t h I ron . 8 flu i d ou n ces

El i x i r of L a c t o- P h os p h at e of Li m e . 8

M i x th e m o o
t o g e t h er .

Each fl u i d drac h m ( t e aspoo n fu l ) o f t h e fi n i shed elix i r

c o ntai ns o n e h al f grai n e ac h o f l ac t o pho s ph at e o f li m e
- -

an d p y ropho sph at e o f i ro n an d r e pr ese n t s t w o grai n s o f ,

O fl i ci nal cali say a

‘
A n elixir s i m il ar t o t h e abo v e w hi ch
.
,

al s o i s abo u t t h e sam e as Wheeler s elixir w as i n t ro ’

d u ced b y M r G F B u t le r i n 1 8 8 1
. . .
, .

EL I X I R O F C A L I S A YA B ARK W I TH P YRO P H O S P H A TE
O F I RO N AN D P EP S IN .

( EL1x 1 R or C A LtS A V A , I R N O AND P s es . Eu xtR on B RK I R NA , O AND F n es .

E LXR
I I or CIN CH N O A, P Y R O P HO S P H TE
A or IR N OP A ND a rs .
)

El i x i r of C al i s ay a B ark w i t h Pyrop h o s p h at e of I ron . . 8 flui d ou n c e s

El i x i r o f P ep s i n 8

Mi x t he m t oge t her , an d n e u t r alize ,

or re n de r sligh t l y
alk ali n e i f n e ce ssar y b y m e an s o f am m o n i a w at er
, ,
.

E ach fl u id drach m ( t easpoo nfu l) o f t h e fi n i shed elixir

c o n t ai n s o n e grai n e ac h o f p y ropho s ph at e o f iro n an d
sacch arrat e d p e p s i n an d r e pr es e n t s abo u t t w o grai n s o f
,

o ffi c i nal cali sa y a b ark .

 E LI XIR F O R M U L/E .
79

EL I XI R O F C A L I S A YA B ARK W I TH P YR O P H O S P H A T E
O F I RO N A N D S T RYC H N I N E .

( Eu xi R OR CA L Y B RK I R N
IS A A A , O AND S T RY C HN IA . Eu xtR o r CI NCH N
O A, I RO N
AND S T RYCHN E m IA . u x or B RK IR N
A ,S O AN D T v uNl A . F ER
R TED E m A u x or B R K w ST RYCHN
A rr u IA

El i x i r of C al i s ay a B ark w ith Pe p h o s p h a t e of

I ro n 1 6 flui d ou n c e s

S t ry c h n i n e 2 % g rai n s
A c et i c A c i d , a s u ffi ci e n t q u an t i t y .

Po w der t h e s t ry ch n i n e ; di ssol v e i t i n a s u fli ci ent

am o u n t o f ac e t i c ac id an d add t h e eli x ir o f cali say a bark
,

w i t h p y ropho s ph at e o f iro n an d i f n e ce ssar y a m m o n ia , , ,

w at er t o n e u t r al iz at io n .

E ach fl u id drach m ( t eas poo nfu l ) o f t h e fi n i shed elixir

c o n tai n s t w o gr ai n s o f p y ropho sph at e o f iro n abo u t o n e ,

fi ft ie t h o f a grai n o f st r y ch n i n e and repre se n t s fo u r ,

grai ns o f O ffi ci nal cali say a b ark Thi s pre p arat io n i s t h at .

r eco mm e n ded b y t h e A m eri can Ph ar m ace u t i cal A ss o

ci at i o n , 1 8 75 .

EL I XI R O F C I N C H O N I N E .

C i n c h on i n e Al k al o i d 2 56 g r ai n s

S i m p l e E l i x i r, P h os p h ori c A ci d (U S P . . .
, o f ea c h a

s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e po w dered c i n ch o n i n e i n a m ortar w i t h ,

t hr ee fl u id o u n ce s o f s i m ple elixir an d di ss ol v e i t b y t h e ,

grad u al add i tio n o f a s u ffi c ie nt am o u nt o f pho sphori c

ac id ; t he n m i x t hi s s ol u t io n w i t h a s u ffi c ie n t am o u n t o f

s i m ple e li xir t o m ak e t h e w hole m e as u re s ix t e en fl u id

o u n ce s ; an d fil t er i f n e ce ssary ,

E ac h fl u id drach m ( t e as poo n fu l ) O f t h e fi n i s hed e lixir

c o n tai n s o f pho s ph at e o f c i n cho n i n e an am o u n t w hi ch i s ,

eq u i v ale nt t o t w o grai n s o f c i nc ho n i ne .
80 ELI XI R F o R M U La .

E L I X I R O F P H O S P H A T ES O F C I N C H O N I N E A N D C IN
CH O N ID IN E .

M i x eq u al a m o u n ts b y m e asu re elix i r of ph o sphate

, , of

o f c i n cho n i n e an d elixir o f pho s pha t e o f c i ncho n idi n e

, .

Ea ch fl u id drach m o f t h e fi n i shed elixi r co n tai n s o f

pho sph ate of ci ncho n idi n e an am o u nt w hi ch i s eq u i v ale nt
t o o n e h al f grai n o f ci ncho n idi ne
-
and o f pho s ph at e o f ,

c i ncho n i n e an a m o u n t w hi c h i s eq u i v ale n t t o on e grai n o f

c i nch o n i n e .

E L I XI R OF P HO S P HATES OF CINCH O N IN E A ND
S T R YC H N I N E .

S t ry ch n i n e g r ai n s

El i x i r of P h os p h at e of C i n c h on i n e 1 6 flui d ou n c e s

P h o s p h o ri c A ci d (U S P
. . .
, a s u fl i ci en t q u an
t i ty .

T ri t u rat e t h e p ow dered st ry ch ni ne i n a m o rtar w i th ,

s u ffi c ie n t pho s phori c ac id grad u all y added t o e ffect i ts, ,

s ol u t io n ; t he n add t h e elixir o f pho sph at e o f c i n c ho n i n e ,

an d fil t er i f ne ce ssary
, .

Each fl u id drach m ( t e aspoo nfu l ) of th e fi n i sh ed elixir

c o n tai n s o f pho spha t e s o f c i n c ho n i n e an d st ry c h n i n e an

am o u n t w h i ch i s eq u i v ale n t t o t w o grai ns o f ci n cho n i n e ,

an d o n e fi fti e th o f a grai n o f st r y ch n i n e
-
.

ELI XI R O F P H O S P HA TE O F C I N C HO N I D I N E .

( En x u or P n os ru A r n'
or CI NCH N D O I I A. Eu x IR or CI NCH N D O I IA .
)

C i n c h on i d i n e ( Al k al o i d ) 128 g rai n s
S i m p l e E l i x i r, P h os p h ori c A c i d ( U S P . . .
, of ea c h a

s u fl i c i e n t q u an t i ty .

Po w der th e ci n cho n idi n e and t ri t u rate i t i n a m or t ar ,

w i th t w o fl u id o u nce s o f si m ple elixir Whe n a sm oo th .

,
82 EL I XIR F o R M U La
e

EL I XI R O F P H O S P H AT ES O F CIN C HO N ID I N E AN D
S T RY C H N I N E .

( EL I X I R or C 1 N cu O N m t A AND Se cu Ni A.)

El i x i r of P h os p h a t e of C i n c h on i d i n e 16 flu i d ou n c es

P h os p h ori c A c i d (U . S P
. .
, 1 8 72 a s u ffi c i e n t q u a n t i ty .

Tri t u rat e th e po w dered st ry ch n i n e i n a m or tar w i t h ,

s u ffi cie n t ho sphori c acid t o e ffe ct i t s s ol u t io n ; th e n add

p
t h e elixi r o f c i ncho n idi n e an d fil t e r i f n e ce ssar y , , .

E ach fl u id drach m ( te as poo nfu l ) o f t h e fi ni shed elixi r

c o n t ai n s o f ph o s ph at e s o f c i n c ho n idi ne an d st ry ch n i n e an

a m o u n t w hi ch i s eq u i v ale n t to o ne grai n o f ci ncho n idi ne ,

an d o n e fi ft i et h o f a grai n o f st r y ch n i n e
-
.

E L I X I R O F A C ET A T E O F C H I N O I D I N E .

(E LXR
I I or C H I N O I D I EN .
)
C h i n oi d i n e g rai n s

D i s t i l l ed W at er 4 flu i d ou n c es

A c et i c A c i d , S i m p l e E l i x i r, of e ac h a s u ffi c i en t

q u an t i t y .

Po w der th e C hi n oid i n e an d di ssol v e i t i n th e d i st illed

w at er b y t h e add i t io n o f a s u ffi ci e n t am o u n t o f ace t i c
a cid then ad d o f si m ple elixir u nt il s ix t ee n fl u id o u nce s
,

are prod u ced and fi l t er , .

Each fl u id drach m ( t e as poo n fu l) o f th e fi n i shed e l i xi r

c o n tai n s t w o grai ns o f C hi n oidi n e .

CO M PO U ND EL I X I R O F C H IN O ID INE .

El i xi r of C h i n oi d i n e 8 flu i d ou n c es

El i x i r of D an d el i on 8

Mix t he m t oge ther . Thi s gr ees prac t i call y w i th

a , ,

t h e for m u l a adop t ed by th e J oi nt C o m m i t t ee o f t h e
 E LI XIR F o R M U LAs . 83

N at io nal C ollege Ph ar m acy an d t h e Me d i cal So cie ty

of ,

o f t h e D i st ri ct o f C ol u m bi a .

Each fl u id drach m ( t e aspoo n fu l ) o f th e fi n i shed elixi r

c o n tai n s o n e grai n o f C hi n oidi n e an d repre s e n ts ab o u t ,

fo u r m i n i m s o f fl u id ex t ract O f d an delio n .

EL I X I R O F B I S U L P H A T E O F QU I N I N E .

( Eu x m or S UL H T E
P A or QU N 1 1A .
)
S u l p h at e of Qu i n i n e 1 28 g rai n s

S i m p l e El i x i r 1 6 flu i d o u n ce s

D i l u t e S u l p h u ri c A c i d , a s u ffi c i e n t q u an t i ty
'

Mix th e su lph at e
q u i n i n e w i t h fo u r fl u id o u n c e s o f
Of

s i m ple el ixir an d ad d e n o u gh d il u t e s u lph u r i c a c id t o e f

,

fe et i t s s ol u t io n The n ad d t h e re m ai n der o f t h e s i m ple

.

elixir an d fi l t er i f n e ce ssary
, , .

Each fl u id d rach m ( t e aspoo nfu l ) o f t h e fi n i shed eli xir

co n tai n s o n e gr ai n o f s u lph at e o f q u i n i n e .

The addi t io n o f t h e ex ce ss o f s u lph u ri c acid act u all y ,

prod u ce s bi s u lph at e o f q u i n i n e ; he n ce t h e t er m elixir o f ,

bi su lph at e o f q u i n i ne i s ad m i ss i ble al t ho u gh su lph at e o f ,

q u i n i n e i s e m plo y ed .

EL I X I R O F I i Y D R O B R O M A T E O F Q U ININ E .

( Eu xw OF B R M DE
O I OF Q 1 1N1 A
‘

.
)
H y d rob rom at e of Q u i n i n e
‘
1 28 g rai n s

S i m p l e E l i x i r H y d rob rom i c
, A ci d , of eac h a s u ffi ci e n t

q u a n t i ty .

Mix h y d robro m ate o f q u i n i n e w i t h t h e si m ple

th e
elixir an d cau t io u sl y ad d o f h y drobro m i c acid an am o u nt
, ,

su ffi c ie n t t o e ffe c t i t s s ol u t io n F il t er i f n e c e ssar y
.
, .

E ach fl u id drach m ( t eas poo n fu l) o f t h e fi n i sh e d elixi r

c o n t ai n s o ne grai n o f h d robro m at e o f q u i n i n e
y .
 E LI XIR F O R M U L/E .

The t er m o ft e n u sed fo r t hi s su b stance bro m ide o f

q u i n i ne — i s i n corre ct si n ce alk aloid s c o m bi ne bodi l y
”

w i t h acid s .

E L I XI R O F P H O S P H A T E O F QU I N I N E .

(E LXR
I I OP QU N N E
I I . Bu xi x or P H OSP H TE Q
A or A )
u rN t .

Qu i n i n e ( Al k al o i d ) 1 28 g ins
ra

S i m p l e E l i x i r , P h o s p h o ri c A c i d ( U S P . . .
, of ea c h a

s u ffi ci en t q u an t i t y .

Po w der t h e q u i n i n e an d t ri t u rat e i t i n a m ortar w i t h

,

t w o fl u id o u nce s o f s i m pl e elixi r Whe n a s m oo t h .

,

c re am y m ix t u re re s u l t s ; c o n t i n u e t h e t ri t u rat i o n an d ,

grad u all y ad d o f pho sph ori c acid an am o u n t s u ffi c i e n t t o

di ssol v e t h e q u i n i n e The n m i x t hi s s o l u t io n w i t h a s u ffi
.

c ie n t am o u n t o f s i m ple elixi r t o make t h e w hole m e as u re

s ix t ee n fl u id o u nce s .

Each fl u i d drach m ( t easpoo n fu l ) o f th e fi n i shed elixir

c o n tai n s o f pho s ph at e o f q u i n i n e an a m o u nt w hi ch i s

eq u i v ale nt t o o ne grai n of q u i n i n e .

EL I X I R O F P H O S P H A T E O F QU I N I N E AN D C IN C H O N I
D IN E .

El i x i r of P h os p h at e of Q u i n i n e an d El i xi r of P h os p h at e of C i n c h on
i d i n e, e q u al am ou n t s b y m e a s u re .

M i x t he m t oge t h e r .

Each fl u id drach m ( t e aspoo nfu l ) o f th e fi ni shed elixi r

co n t ai ns o f pho s ph at e o f q u i n i n e an d o f pho s ph at e o f

c i n c ho n idi n e an am o u n t w hi c h i s eq u i v ale n t t o o n e hal f

,
-

grai n e ach o f q u i n i n e and o f c i n cho n idi n e .

 EL I XI R F O R M U LIE . 85

EL I XI R O F P H O S P H A T E O F QU I N I N E A N D CINC HO N IN E .

(E LXR
I I OF QU N I IA A ND C i Nc HO N i A )
.

El i x i r of P h o s p h at e of Qu i n i n e , an d El i x i r of P h os p h a t e of C i n ch o
n i n e , o i ea c h e q u al am o u n t s b y m e a s u re .

M i x t he m t oge t h e r .

Each fl u id d rac h m ( t easpoo n fu l ) o f t h e fi n i shed elixir

c o n t ai n s o f pho s ph at e o f q u i n i n e an am o u n t w hi c h i s

eq u i v ale nt t o o n e h al f grai n o f q u i n i n e ; an d o f pho sph at e

-

o f c i n cho n i n e an am o u n t w hi c h i s eq u i v ale n t t o o ne grai n

of ci n c ho n i n e .

ELIXI R O F P H O S P H A T ES O F QU I N I N E , CI N C H O N ID IN E
AN D CIN C HO N IN E .

El i xi r of P h os p h a t e of Qu i n i n e , E l i xi r of P h o s p h at e of C i n c h on i
d i n e, an d El i x i r of P h os p h a t e of C i n c h on i n e , of e a c h e q u al
a m ou n t s b y m eas u re .

M i x t he m t oge t her .

Each fl u id drac h m ( t e as poo n fu l ) o f t h e fi n i shed elixir

c o n tai n s o f pho sph ate O f q u i n i n e an am o u nt w h i c h i s

eq u i v ale n t t o o ne t hird grai n o f q u i n i n e an d O f pho s ph at e

-

o f c i n c ho n id i n e an am o u n t w hi c h i s eq u i v ale n t t o o n e

t hird o f a grai n o f c i n c ho n idi n e an d o f pho s ph at e o f ,

c i n c ho n i n e an am o u n t w hi c h i s eq u al t o t w o t h ird s o f a -

grai n o f c i n cho n i n e .

EL I XI R O F P H O S P H A T E O F Q U I N I N E W I TH C I T RATE
O F P RO TO XI D E O F I RO N

( Eu x tR o r P R T X DE
O O I OF I R N W T H QU N
O EI I IA . u x tR or QU N N E
I I AND F ER R UO S

PH H TE ) OSP A .

El i x i r of P rot ox i d e of I r on 8 flu i d o u n c es

El i xi r of P h os p h a t e of Qu i n i n e 8

M i x t he m t oge th e r .

Eac h fl u id drac h m ( t eas poo n fu l ) of th e fi n i s hed e lixi r

86 EL l X I R F O R M U L/E .

co n tai ns o ne h al f grai n o f q u i n i n e an d as m u ch c i tra t e o f

-
,

pro t oxide o f iro n as corr e spo n d s w i t h o ne grai n o f s u l

h at e o f iro n Thi s e lixi r i s no t v ery stable
p
. .

EL I X I R OF P H O S P H A T E O F Q U I N I N E W I T H C I TRA T E
O F P RO T O X I D E O F I RO N A N D S T RYC H N I N E .

(B u xi x O P QU N 1
1 A PR T X DE
A ND IR N
O O I S T RYCHN
or E O n Q A ND IA . u xx OF U1

N E F E RR U C T R TE
NI , O S T RYCHN E )
S I A AND IN .

E l i x i r of P h os p h at e o f Q u i n i n e w i t h C i t rat e of P ro
t ox i d e o f I ro n 16 fl u i d ou n c es
S t ry c h n i n e
A c et i c A c i d , a s u fli c i e n t q u an t i t y .

Tri t u rat e t h e s t r y ch n i n e i n a m ortar cau t io u s l y addi ng ,

ace t i c ac id i n am o u n t s u ffi c ie n t t o e ffe ct i ts s o l u t io n and ,

m i x t h i s w i t h t h e elixir O f pho spha t e o f q u i n i n e an d

c i tr at e o f pro t oxide o f iro n .

Each fl u id drac h m ( t e aspoo n fu l ) o f th e fi n i shed elixir

c o n tai n s o n e h al f gr ai n o f q u i n i n e
-
as m u ch c i t rat e o f ,

pro t oxide o f i ro n as c orr es po nd s w i t h o n e grai n O f s u l

ph at e o f i ro n an d o n e fift i e t h grai n O f s t ry ch n i ne
,
-
.

The ter m pro t oxid e o f i ro n i s a m i sn o m er See

, , .

o u r re m ark c o n c er n i ng elixir o f cali say a b ark w i t h pro

t o x i de o f iro n Thi s prep arat io n i s u nstable

. .

EL I XI R O F P HO S P H ATE OF QU I N I N E AN D S T RYC H
N IN E .

( Eu xm or QU N1 1A A ND ST v nN t A .
)

Qu i n i n e A l k al o i d )
S t ry c h n i n e
S i m p l e E l i x i r , P h o s p h o ri c A c i d ( U S P . . .
, o f e ac h

a s u fl i c i e n t q u an t i t y
'
.

Tri t u rate t h e po w d e r e d s t ry ch n i n e i n a m or tar w i t h ,

t w o fl u id o u n c e s o f s i m pl e e lixir an d di s s ol v e b y addi ,
 11 1 1l
. F O R M U L/E . 87

t io n ofa s u ffi c ie nt am o u n t o f pho s phori c ac id N o w .

ad d t h e q u i n i n e ( pr e v io u s l y po w der e d ) an d t he n c o n t i n , ,

u i ng t h e t ri t u r at io n grad u all y ad d o f pho s phori c ac id an

,

am o u n t s u ffi c ie n t t o di s s ol v e t h e q u i n i n e Th en m i x t hi s .

s ol u t io n w i t h a s u ffi c ie n t am o u n t o f s i m p l e e lixir t o m ake

t h e w hole m e as u re s ix t ee n fl u id o u nc e s an d fil t er if , ,

n e c e s s ar y .

E ach fl u id d rach m ( t e aspoo n fu l ) o f t h e fi n i shed elixir

c o n t ai n s o f pho s ph at e o f q u i n i n e an d pho sph at e o f s t r y c h

n i n e an am o u n t w h i c h i s eq u i v ale n t t o o n e gr ai n o f q u i
,

n i n e an d o n e fift i e t h o f a gr ai n o f st r y c h n i n e
,
-
.

EL IXI R O F V AL ERIAN AT E O F QU I N I N E .

V al e ri an at e of Qu i n i n e 1 28 g rai n s
S i m p l e El i x i r 1 6 flui d ou n c es

V a l e ri a n i c A c i d , 2 s u fli c i en t q u an t i t y .

Po w der t h e v aleri anat e o f q u i n i n e i n a m ort ar and ,

grad u all y add t h e s i m ple elixir The n cau t i ou sl y drop .

i n t o t h e m ix t u re v aleri an i c ac id s u ffi c ie n t t o re nder t h e

liq u id t ran s pare n t s t irri ng c o n t i n u all y and fil t er i f n eces
, , ,

sary .

Th i s for m u l a co n for m s t o t h at by Pro f C L e w i s D ieh l . .

re ad be fore t h e L o u i sv ille C ollege o f Ph ar m acy .

Each fl u id drach m ( teas poo nfu l ) o f t h e fi n i shed elixi r

c o n tai n s o n e grai n o f v aleri anat e O f q u i n i n e .
88 ELI X IR FO R M U LAJ
‘
.

EL IXI R O F V A L ERI A N AT E O F Q U IN IN E W I TH S T RYC H

N IN E .

( Eu x m or V LE R N TE
A IA A or QU N I IA AN D S T RYC H N IA .
)

El i x i r of V a l e r i an at e of Qu i n i n e 14 flui d ou n c es

D i st i l l ed W at er 2

S t ry c h n i n e 2
74 g ra i n s

V al eri an i c A c i d , a s u fl i ci en t
'

q u an t i t y .

P o w de r t h e st r y c h n i n e i n a m ortar and add th e w at er ,

an d t h e n e n o u gh v aleri an i c ac id t o e ffe ct t h e s ol u t io n o f

t h e st ry c h n i n e Last l y ad d t h e s i m ple elixir and fil t er

.
, , ,

i f n e c e ssar y .

E ac h fl u id d rach m ( t eas poo n fu l ) w ill co ntai n abo u t o ne

grai n o f v aleri anat e o f q u i n i ne an d o ne fi fti eth grai n o f
,
-

q u i n i ne .
9 0 ELI X IR F O R M U LH
E .

C an d id u s stat ed t h at t hi s
elixir co m ple t el y m as k s t h e
bi tt er tas t e o f s u lph at e o f q u i n i n e an d h e r ec o m m e n ded
,

i t as a v ehi c le fo r ad m i n i s te ri ng t h at s u b stan c e S i n ce .

o n e o f t h e i n gredie n t s i s liq u ori c e s ee e lixi r o f

( l
g y y
c rr

h i z i n) w e m ay s u ppo s e t h at gl y cy rrhizi n aid s i n o v er

,

c o m i n g t h e bi t t er n e ss an d o u r r e m ark s c o n c er n i n g q u i
,

n i n e and gl y cy rrhi z i n s ho u ld be appli cable t o t hi s elixi r

, .

The for m u l a w e pre se n t doe s n o t mat e ri all y v ary fro m

t h at o ffe red b y Pro f C an did u s e x cep t i ng i n t h e s u b s t i t u
.
,

t i o n o f fl u id ex t r ac ts fo r c r u de dr u g s .

E L I XI R O F D A N D EL I O N W I TH Q U I N I N E .

( Eu x m OF T A RAxA C U M A ND QU N1 1A .
)

El i x i r of D an d e l i o n 8 flu i d ou n c e s

El i x i r of P h os p h a t e of Qu i n i n e 8

M i x the m t oge t h e r .

Each fl u id drach m ( t e as poo n fu l ) o f t h e fi n i s hed elixir

co n t ai n s t hr e e an d o n e fo u r t h m i n i m s o f fl u id ex t ract o f
-

tarax ac u m an d o n e h al f grai n o f q u i n i n e
,
-
.

I n t h e y e ar 1 8 73 M r J am e s W L o n g fu rn i shed t h e
, . .

Amerz can j ou r nal of P i zarmacy w i t h a pro ce ss fo r m aki ng

t h e abo v e prepara ti on .
 ELI XIR F O R M U LIE .
9 1

D A F F Y S E L I XI R
’
.

(D l L LY s
’
D A FF Y ; Eu xm OF H E LT H
A . N ew D
'

zs f en ra to ry Lon d on , ,

G u ai ac W oo d
E l e c a m p a n e R oo t 2

A n i s e S eed 2

C a raw ay S e e d 2

C or i an d er S e e d
L i q u ori c e R oot
R ai s i n s
D i l u t e d A l coh ol

Red u ce d r u g s t o a co ar se po w der an d m i x t he m
th e ,

w i t h t h e dil u t ed al cohol Th e n see d t h e rai s i n s chop

.
,

t he m fi n e ad d t o t h e m ix t u re an d m acerat e fo u r t ee n
, ,

d ay s st irri n g th e m ix t u re t h oro u ghl y e ach d ay ; t he n

,

fi l ter ( S u pple m e n t t o London P /zar macopa i a A f

,

“
n u m ber o f c o m po u n d s h av e bee n o ffe red as D affy s ’

e lixir an d fro m am o n g t he m w e ha v e sele ct ed t h e pre

,

c edi ng .

EL I X I R O F D A M I A N A .

F l u i d Ex t r a c t of D am i a n a 2 fluid ou n c es

S i m p l e El i x i r 1 6
A l coh ol
C a r b on at e of M a g n es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e th e fl u id ex t ract o f d am i ana i n a capa cio u s

m or tar w i t h carbo n at e o f m ag n e s i u m i n am o u n t s u fli
,

c ie n t t o for m a c re am y m ix t u r e t he n grad u all y ad d t h e ,

s i m ple eli xir s t irri n g w ell

, an d fi l t er Last l y m i x t h e
, .
,

fil trat e w i t h t h e al cohol .

Each fl u id drach m o f t h e fi n i s hed elixi r repre se n ts

s e v e n an d a h al f m i n i m s o f fl u id ex t ract o f d am i an a .
9 2 E LI X IR F O R M U LA"“

D EW B E R R Y C O M P O U N D .

EL1 x 1 R R u m T R 1 v 1 A u C O M PO S I T U M )
'
s .

D ew b erry R oot . . 2
N u t g al l s
Ki no
C i n n am o n
C l ov es .

C ap s i c u m g ra i n s

T i n c t u re O pi um 1 flui d ou n c e

E s s en c e P epp erm i n t %1fl u i d d ra c h m s

B ra n d y 32 fl u i d ou n ces
S u g ar I 4 t roy ou n c es

Red u ce t h edr u g s to a c oarse po w der and m ac erat e i n ,

t h e bran d y fo r fo u r t ee n d ay s s t i r ri n g t h e m ix t u re t ho r
,

o u ghl y each d ay t he n fil t er and d i sso l v e t h e s u gar i n

, ,

t h e fil t ra t e .

( N e w R e m ed i es ,

EL I X I R O F E U C A LY P T U S
’
.

F l u i d E x t rac t of E u cal y p t u s 2 flu i d ou n ces

S i m p l e El i x i r

C arb o n at e of M agn es i u m , a s u fli c i e n t q u an t i t y .

Tri t u ra t e t he fl u id ex t rac t o f e u cal y p tu s w i t h carbo nat e

o f m ag n e s i u m i n s u ffi c i e n t am o u n t t o form a cre am y m i x

t u re t he n grad u all y ad d t h e s i m ple elixir and fil t er

, , .

L ast l y m i x t h e al cohol w i t h t h e fil t rat e

, .

Each fl u id drach m o f t h e fi n i shed prep arat io n w ill co n

t ai n s u ch propor t io n o f s e v e n and a h al f m i n i m s o f fl u id
e x t rac t o f e u cal y p t u s as w ill di s s ol v e i n t h at am o u n t o f

t h e m ens t r u u m I n o u r opi n io n t h e proper m e n st r u u m

.
,

fo r ex t ract i ng t h e m edi c i nal pri n ciple s o f e u cal y p t u s i s ,

al c oh ol o f s pe c ifi c grav i t y Th e add i t io n o f w at er
de t rac ts fro m i t s v al u e as a di ss ol v i ng m edi u m i n propor ,
 ELI XIR F o R M U L As
‘

.
93

t io n t o t h e am o u n t of w at er
pre s e n t There for e elixir .
,

o f e u cal y p t u s doe s n o t repr e se n t t h e fl u id ex t rac t o f

e u cal y p t u s e m plo y ed i n maki ng i t .

The p roport io ns O f e u cal y p t u s u po n w h i c h t h e abo v e

eli x ir w as b ased w ill be fo u n d i n t h e D mcgg zlrts Ci rcul ar
,
’

1 8 77 .

CO M PO U ND E L I XI R O F EU C ALYP TU S .

F l u i d E x t ra c t of Eu c al y p t u s 2 flu i d ou n c e s

F l u i d E x t rac t of Li q u or i c e R oot
F l u i d E x t ra c t of W i l d C h e rry
S i m p l e El i x i r
C arb o n at e of M ag n es i u m , a s u fli c i e n t q u an t i t y .

M i x t h e fl u id ex t ract s ri t u rat e t he m i n a cap acio us

an d t

m or tar w i t h carbo n at e o f mag n e s i u m i n am o u n t s u fl i

,
‘

c ie n t t o for m a c re am y m i x t u re t he n grad u all y add t h e ,

s i m ple el ix ir st ir r i n g w ell
, t he n fi l t er , .

Each fl u id d rach m o f t h e fi n i shed e lixir repre se n ts

s u c h an am o u n t o f se v e n an d a h al f m i n i m s o f fl u id ex

t ract O f e u cal y p t u s as w ill di ss ol v e i n o n e fl u id drach m o f

t h e fi n i sh e d m e ns t r u u m an d abo u t t w o m i n i m s e ac h o f
,

t h e fl u id ex t rac t s o f liq u ori ce roo t an d w ild c herry .

T h i s prep ar at io n i s i n t e n ded as a pl easan t m od e o f ad

m i n i st eri ng e u cal y p t u s ; b u t t h e propor t io n o f e u cal y p t u s
r epre se n t ed i s u ncer tai n o w i ng t o t h e fact t h at al c oh o l o f
,

s pe c ifi c grav i t y i s t h e proper s ol v e n t fo r t h e m e di c
i nal pri ncipl e s o f th e leav e s T h e for m u l a w e pre s e n t i s
.

b ase d u po n i ngredie n ts s u gge st ed i n t h e D ruggnlrts Ci rca ’

l ar , 1 8 77 .
 ELI X I R F O R M U La
94 .

EL IXIR D E GA R U S .

M y rrh

R ed u c e t h e d r u g s t o a co arse po w der m i x t hi s
. , w i th
t he al c ohol an d di st ill n i n e pi n t s
, Re ser v e t hi s . .

M ai d e n h a i r 4 t r oy ou n c e s

L i q u ori c e R oot
F i gs

I n fu s e t h e s e i n e igh t pi nt s o f boi l i ng w at er st rai n w i t h ,

expre ss io n and ,
di s sol v e i n t h e liq u id t w el v e av oird u poi s
po u n d s of s u gar .

Eq u al p ar ts b y w eigh t o f t hi s s y r u p and o f t h e di s
, ,

t ill e d s piri t prod uce

“
e li x ir de g ar u s accordi n g t o t h e
”

, ,

s u pple m e n t t o t h e L o n do n Ph ar m aco p a i a 1 82 1 , .

Thi s cu m b e r s o m e an d u n scie nt ifi c m ix t u re a r e li c o f ,

t h e an c ie n t pol y ph ar m acy i s h appil y n earl y O b s ole t e

-
, .

EL I X I R O F G E N T I A N .

F l u i d E x t rac t of G en t i a n 2 flu i d ou n c es

S i m pl e El i x i r
A l c oh ol
C ar b o n a t e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e fl u id e x t ract o f ge n t i an i n a cap acio u s

m ort ar w i t h carbo n at e o f m ag n e si u m i n am o u nt s u ffi
,

c i e n t t o for m a c r e am y m ix t u re t h e n gr ad u all y add t h e ,

s i m ple elixir s t irri n g w e ll

,
and fil t er L as t l y m i x th e
,
.
,

fi l tra te w i t h t h e al co ho l .
 E LI XIR F O R M U LJE .
95

E ach fl u i d d rach m o f t h e fi n i s h e d e lixir r e pre se n ts

s e v e n an d o n e h al f m i n i m s o f fl u id e x t rac t o f g e n t i an
-
.

CO M P O U N D EL I XI R O F G EN TI A N .

F l u i d E x t ra c t of n
G e t i an , C o m p ou n d 2 flui d ou n ces

S i m p l e El i x i r 1 6
C arb on at e of M ag n e s i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e co m po u n d fl u id ex t ract o f ge nt i an w i t h

c arbo nat e o f m ag n es i u m i n s u ffi c ie n t am o u n t t o fo rm a

c re amy m ix t u re t he n gr ad u all y ad d t h e s i m ple elixi r an d

,

fil t er .

Each fl u id drac h m o f t h i s elixir repre se nt s t h e v i rt u e s

o f s e v e n an d o n e h al f m i n i m s o f co m po u n d fl u id ex t ract
-

o f ge nt i an .

EL I XI R O F W I LD G I N G ER .

F l u i d Ex t ract of W ild Gi n ger 1 flu i d ou n ce

F l u i d E x t ra ct of P l e u ri s y .

F l u i d E x t r ac t of J u n i p er B e rri e s

F l u i d E x t ra c t of Ani se ( or Po w d ered A n i se , 1 20 g r ai n s )
F l u i d E x t ra c t of C a raw ay ( or Po w d ered C araw ay , 1 20

g r ai n s )
S i m p l e El i x i r
A l c oh ol
C arb on at e of M ag n e s i u m , a s u fl i ci en t q u an t i ty .

Tri t u rate t h e m ix e d fl u id ex t ract s i n a cap acio u s m o r

t ar w i t h carbo nat e o f m ag n e s i u m i n am o u n t s u ffi c ie n t t o
,

for m a c re am y m ix t u r e t h e n gr ad u all y add t h e s i m ple

,

elixir st irri n g w ell an d fil t e r L ast l y m i x t h e fil t rat e

, ,
.
,

w i t h t h e al c ohol .

Each fl u id drach m o f t h e fi n i sh e d e lixir r e pre se n ts

abo u t t hree an d o n e h al f m i n i m s o f fl u i d e x t rac t O f w ild
-

g i n g er an d, o n e an d t hr e e fo u r t h s e ac h o f fl u id ex t
-
r ac t o f
 6 nu x m F O R M U LAt
9 .

ple u ri sy and j u n i per berrie s Thi s co m po u nd w as s u g

.

ge ste d i n 1 8 77 b y M r T F Th o rw o rth i n t h e D mg
, . . .
,

i Ci l
’

g sts rcu ar .

E L I X I R O F G L Y C Y R R H IZ I N .

A m m on i ac al G l y c y rrh i z i n 1 28 g ra i n s

S i m p l e El i x i r 1 6 flui d ou n c es

D i ss ol v e t h e gl y cy rrhizi n i n t h e s i m ple elixi r , and fil t er

if e e ry
n c ssa .

Each fl u id d ra ch m ( teaspoo n fu l) o f th e fi n i shed elixi r

c o nt ai n s o ne gr ai n o f am m o n i acal gl y cy rrhizi n Thi s .

e lixir i s u sed t o di sg u i s e t h e bi tt er n e s s o f q u i n i n e ; b u t i t

m u st be re m e m bered t h at q u i n i ne w ill n o t d i ssol v e i n i t ,

an d t h at q u i n i n e i s pre c ipi tat ed b y am m o n i acal gl y crrh i

z i n fro m sol u t io n s w h i ch are n o t s t ro ng l y ac id H e n ce .

,

t h e r eas o n fo r t h e tas t e le ssn e ss o f q u i n i n e u n der t he se

c o n di t io n s i s l argel y d u e t o i t s i n sol u ble stat e S u ch .

m i x t u re s sho u ld b e s h ake n be fore t aki ng e ac h do se and ,

u n der n o c o n di t io n s ho u ld t h e m ix t u re be fil t ered as t h e ,

q u i n i n e w ill th e n re m ai n o n t h e fi l t e r p aper The ab ov e .

for m u l a i s t h at o f Pro f J o s e p h Re mi ng t o n
. .
 E LI XIR F O R M U L/E .

EL I X I R O F G R I ND E L I A R O B U S TA .

( Bu xi n O F G R ND E L
I IA .
)

F l u i d E x t ra c t of G ri n d el i a R ob u s t a 2 flui d o u n c es

S i m p l e El i x i r
A l coh ol
C a rb on at e of M ag n es i u m , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e fl u id ex t ract o f gri ndeli a i n a cap ac io u s

m or t ar w i t h carbo n at e o f m agn e s i u m i n am o u nt s u ffi
,

c ie n t t o for m a c re am y m ix t u re t he n grad u all y ad d t h e

,

s i m ple elixir s t irri n g w ell

, an d fil t er L ast l y m i x t h e
,
.
,

fil t rat e w i t h t h e al cohol .

E ach fl u id drac h m o f th e fi n i shed elixi r repre se nt s su ch

an am o u n t o f s e v e n an d a h al f m i n i m s o f fl u id ex t ract o f

g ri n de l i a rob u st a as w ill di ssol v e i n t h e m e n s t r u u m .

Gri n deli a rob u st a co ntai n s a re si n w hi ch i s pre c ipi tat ed by

w at er ; he n ce w e do no t c o ns ider an elixir o f t hi s pl an t
,

t o be de s i rab l e .

EL IX I R O F G U A RA N A .

F l u i d E x t ra c t of G u ar an a 2 flu i d ou n c e s

S i m p l e El i x i r
C arb o n at e of M ag n es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rate th e fl u id ex tract o f g u aran a i n a cap ac io u s

m or t ar w i t h carbo na t e o f m ag n e s i u m i n am o u n t su ffi
,

c i e n t t o for m a c re am y m ix t u r e t he n grad u all y ad d t h e ,

s i m ple elixir st irri n

, g w ell and fi l ter Last l y m i x t h e
,
.
,

fil t rat e w i t h t h e al cohol .

E ach fl u id drac h m ( t e aspoo nful ) o f t h e fi n i shed elixir

repre sen t s se v e n an d a h al f m i n i m s o f fl u id ex t ract o f
g u arana an d i s essen t i all y th e sam e as t h at r ec o m m e n d e d
,

b y t h e A m eri can Ph ar m ace u t i cal A ss o c i at io n 1 8 75 In , .

t h e same y ear M r Geo W K e nn ed y t hro u gh th e

. . .
,
 EL I X IR F O R M U LAE .
99

Amer i can j ou rna l f

o P h ar macy , g av e a for m u l a fo r t hi s
el i xir e ach fl u id
,
drach m o f w hi c h r e pre se n t ed fi ft ee n
grai n s o f g u arana .

E L I XI R O F G U A I A C U M .

G u m G u ai a c u m ( p u l v er i z ed ) 2 t roy ou n ce s

B al s a m of P e ru 2 flui d d rac h m s
O il of S a s s afras 1

V ol at i l e O i l y S p i ri t it 1

D ige st t h e gu m g u ai ac u m b al sam o f Per u i n t h e

and

v ol at ile oil y spiri t for si x d ay s i n a clo sel y st opp e d v i al

, ,

w hi c h i s n o w an d t he n sh ake n ; aft er w ard s s t rai n t h e

t i n ct u re and add t o i t t h e e sse n t i al oi l o f sa ssafras ”

.

( Ed i n bu rg h P h ar maco p e i a,

EL I XI R A C I D U M H A L L ER I .

( H A LLRR A c 1 D Eu
’
s xt R .
)
S u l p h u ri c A ci d 1 t roy ou n c es

A l coh ol 3

Add t h e s u lph u ri c acid t o t h e al cohol drop by drop , ,

s t irri n g co n stan t l y Pre s er v e t h e fi n i sh e d e lixir i n gl ass

.

s t opped bo t t le s Thi s i s t h e pro ce ss o f t h e G e r m an

.

Ph ar m acop oei a 1 8 72 an d i s e sse n t i all y th e sam e as elixir

, ,

acid u m d i p p el i i w hi c h c o n tai n s o n e p ar t o f su lph u ri c

,

ac id t o t w o p ar t s o f al c ohol .

1°
‘
V l ti l
o a e p
O i l y S i r i t w as mad e as fo ll o w s : Ta k e of

V l il
o at e Sal t o f S al A m m o n -
i a
Es se n t i al O i l o f R o s e m ar y ,
O i l o f A m be r .

Ess e n c e o f Le m o n P e e l ,
Fre n c h B
r an d y ,

D r aw 06 by d i s t i ll at i o n , i n t h e h e a t of a w at e r bat h , n e ar o n e g all o n .

1 g
Ed i n b u r h P h ar m ac o p oei a, 1 770 )
 00 EL I XIR F O R M U LZE .

H EL M O N T ’
S E L I XI R .

A n y F i x ed Al k al i n e S al t f
8 t roy ou n c es

S o cot ri n e A l o es 1

S affro n . 1

M y rr h 1

S al A m m o n i a c . 6 d rach m s
M ou n t ai n W ine T . 2
p i n ts

M ac erat e w i t ho u t he at ,
fo r a w eek or lo nger , t he n fil t e r
t hro u gh paper .

( Lo n d o n Ph ar mac op ce i a,

E L I XI R O F H E L O N I AS .

F l u i d E x t ra c t of H el on i as , C om p ou n d 2 flu i d ou n c es

S i m p l e El i xi r
A l co h ol
C a rb o n at e of M agn es i u m , a s u fli c i e n t q u an t i ty .

Tri t u rat e t he co m po u n d fl u id ex t ract of helo n ia s w i t h

carbo nat e o f m ag n e si u m i n s u ffi c ie n t a m o u n t t o for m a

c re am y m ix t u re t he n grad uall y add t h e s i m ple elixir

, ,

and fil t er M i x th e al c oh ol w i t h t h e fil t rat e
. .

Eac h fl u id drach m o f t h e fi n i shed prep arat io n w ill co n

t ai n su ch propor t io n o f s ev e n and a h al f m i n i m s o f co m
po u n d fl u i d ex t ra ct o f h e lo n i as as w ill di sso l v e i n o ne ,

fl u id drach m o f t h e m e nst r u u m .

i
2‘
Fi q ALK L N E
A I SAU L —
T h i s w as i m u r e p p
o t as s i u m c arbo n at e T o gi v e t h e
fi p g p
.

d e n i t i o n o f t h e N e w D i s en sat o r y 1 770 : T h e as h e s o f mo s t v e e t abl e s , s t e e e d or

p f
,

b oi l e d i n w at e r , g i v e o u t t o i t a s al i n e s u bst an c e, s e arabl e i n a s o l i d o r m by e v ap o r
a ti n gt h e w at e r T his k i n d of sa l t n e v e r r eé x i s t s i n t h e v eg e t abl e s, b u t 1 5 al w ay s
k i
.
”

g e n e rat e d d u r i n g t h e b u r n i ng I t i s c al l e d x t al al n e sal t
. .

1 M o u n t ai n
"
Wi n e of t h at d ay w as Vi num al b u m, Lon d P h arm
. .
, or Vi nu m al b u m
H i s p an i c u m, Ed i n b Ph ar m
. .
1 02 ELI XI R F O R M U LE .

EL I XI R O F HO P S AN D C H I R E TT A .

F l u i d E x t ra c t of H op s 1 flu i d o u n c es

F l u i d E x t ra c t of C h i re t t a
S i m p l e El i xi r
A l c o h ol
C arb on at e of M ag n es i u m , a s u ffi ci e n t q u an t i ty .

Mix fl u id ex t ract s an d t ri t u rat e i n a cap ac io u s

th e
m or tar w i t h carbo nat e o f magn e s i u m i n am o u nt s u ffi
,

c ie n t t o for m a c re am y m ix t u re t he n gr ad u all y ad d t h e ,

s i m ple elixir s t irri ng w ell

, an d fil t er Last l y m i x t h e
, .
,

fil t rat e w i t h th e al cohol .

Each fl u id drach m o f th e fi n i shed elixir repre se nts s u ch

an am o u n t o f t hree an d a h al f m i n i ms e ac h o f fl u id ex

t ract o f hop s an d o f ch ire t ta as w i ll di ss ol v e i n t h e m e n

,

st r u u m u s ed i n t s prep arat io n O u r re mark s regardi n g

i .

c o m po u nd elixir o f hop s may be applied w i t h eq u al p er

,

t i nence t o t h i s .

CO M P O U N D E L I XI R O F HO PS .

F l u i d E x t ract of H ap s 2 flu i d ou n c es

F l u i d E x t ra c t of O ran g e P eel
S i m p l e El i x i r
C a rb on at e of M a g n es i u m , a s u ffi c i e n t q u a n t i t y .

M i x t h e fl u id ex t ract s an d t ri t u rat e t he m i n a ca p acio u s

m or tar ,
w i thrbo nat e o f m ag n e si u m i n am o u n t su ffi
ca

c ie nt t o for m a c re am y m ix t u re t he n grad u all y ad d t h e ,

s i m ple elixir st irri n g w ell

,
an d fi l t er L as t l y m i x t h e
,
.
,

fi l t r at e w i th t h e al cohol .

Eac h fl u id drach m o f t h e fi n i shed el ixi r repre se nt s

s u ch an am o u n t o f s e v e n an d a h al f m i n i m s o f fl u id ex

t ract o f hop s as w ill di ss ol v e i n t h e m e n st r u u m .

The i ngredie n t s fo r t h e ab o v e m ix t u re w ere n am ed by

t h e D ruggvlrts Ci rcul ar
’
1 8 76 We d o n o t c o n sider an
,
.
 EL I X IR F O R M U La . 1 03

a q u eo u s m e n st r u u m to be w ell ad ap t ed t o th e p u rpo se
o f exh au s t i n g t h e m edi c i nal pri n c iple s o f hop s ; he nc e w e ,

t hi n k t h at t hi s elixir i s n o t a de s irable prep arat io n .

H U F EL A N D S E L I XI R
’
.

E x t ra c t of B l es s ed Th i stl e X t roy ou n c e

E x t ra c t of B i t t er S w e e t X
F en n e l W a t er 8 flui d ou n c es

C h e rry L a u r el W at e r I

Mix ex t ract s i n a m or tar and di ssol v e t he m b y

th e ,

t ri t u rat io n w i t h t h e m ixed fe nn el and c h e rry l au rel w a te r ,

an d t he n fil t er .

E L I X I R O F A M M O N I O CI
- TRA TE O F I RO N .

( Bu xi n O P C 1 T R A T 11 OF I R N)
O .

A m m o n i o- C i t rat e of I ron ( So l u bl e C i t rate ) 2 56 g rai n s

S i m p l e E l i x i r, a s u ffi ci e n t q u an t i t y .

D i ssol v e t h e amm n
o io c i t rat e o f iro n i n t w e l v e fl u id
-

o u nce s o f s i m ple elixir and bri ng t hi s t o t h e m e asu re o f

,

s i x t ee n fl u id o u n ce s b y t h e addi t io n o f a su ffi c ie n t q u an

t i t y o f s i m ple elix ir .

Each fl u id drach m ( t e aspoo n fu l ) o f t h e fi n i shed elixir

repre se nts t w o grai n s o f amm o n io c i t rat e o f iro n t h e -
,

s am e as t h at adop t ed b y t h e A m eri ca n Ph ar m ace u t i cal

A sso ci at io n 1 8 73 ,
.
1 04 ELI X IR F o R M U La .

E L I X I R O F I P EC A C .

P ow d ere d I p ec ac t roy ou n c es

B al s am of ol u T
B en z oi c A ci d 2 d rac h m s
O pi u m 2

S affro n 2

C am p h or 2 s cru p l e s

O il of A n i se 1 flu i d d rac h m
A l coh o l 2 p i n t s

M ac erat e dr u g s i n t h e al cohol fo r fo u r t ee n d ay s
th e ,

s t i rri n g t h e m ix t u re t horo u ghl y e ac h d ay t he n fil t er an d ,

di ssol v e t h e ca m phor and O i l o f a n i se i n t h e fil t rate .

EL IX I R O F B RO M I D E O F I RO N .

B rom i d e of I ro n . 2 56 g rai n s

S i m p l e El i x i r 1 6 flu i d ou n c e s

D i ssol v e bro m ide o f iro n i n t h e si m ple elixir b y

th e ,

t ri t u rat i n g t he m t oge t h e r i n a m or tar an d t he n fil t er , .

S ho u ld t h e bro m ide o f iro n fail t o co m ple t el y di ssol v e ,

as i s o ft e n t h e case t h e prod u ct w i ll be acc o rdi ngl y de

,

fi ci en t i n st re ng t h .

Each fl u id d rach m ( t e aspoo n fu l) o f t h e fi n i shed elixir

c o n tai n s t w o gr ai n s o f bro m ide o f i ro n .

EL I XI R O F C I T RA T E O F I R O N W I TH Q U I N I N E AN D
S T RYC H N I N E .

C i t rat e of I ro n an d Qu i n i n e 2 56 g ra i n s

C i t r at e of I ron an d S t ry c h n i n e 1 28

S i m p l e El i x i r 1 4 flu i d ou n c e s

D i s t i l l ed W at e r 2

D i ssol v e i t rat e s i n t h e di st illed w at e r u si ng a

th e c ,

m oderat e he at i f req u ired ; t he n ad d t h e s i m ple elixir

, ,

and fil t er i f n e ce ssar y
,
.
1 06 ELI X IR F O R M U LI E .

an d pro ce ss e m p l o y ed i n m aki ng i t S i nce i ts i nt ro d u c .

t io n t hi s elixir h as e nj o y ed a pop u l ari t y w h i c h co m

m an d s fo r i t a c o nstan t sale am o ng ph y s i c i an s an d w e ,

cau t io n ph y s i c i an s agai n st co nfu s i ng i t w i t h t h e elix i r s

w e gi v e for m u l a fo r m aki ng an d w h i ch are n o t elixir s O f ,

pro t oxide o f iro n al t ho u gh i n co mm erce t he y h av e de

,

ri v ed t h at t i t le .

ELI XI R O F C I TRAT E A N D L A C TA T E O F I R O N .

( Eu x rR O F C l T R O -L A CT TE
A OF I R ON .
)
L ac t at e Of I ron 96 g r ai n s
C i t rat e Of I ron 96
W at er 7 flui d ou n c es

A l c oh ol .
5
S i m p l e S y ru p 9
E s s e n c e o f L em on 96 m inims
E s s en c e of C l ov e s r

Mix di st illed w at er an d sy r u p and di ssol v e i n i t

th e ,

t h e l actat e O f iro n t h e n ad d and di ssol v e t h e c i t rat e o f

,

iro n ; c ool an d m i x w i t h t h i s sol u t io n t h e si m p le sy r u p

,

an d t h e al cohol h av i n g pre v io u s l y m ixed t h e al cohol

,

an d e sse n c e s t oge t her L ast l y color t h e prod u ct w i t h

.
,

caram el u n t i l i t i s abo u t t h e c olor o f bran d y an d t he n ,

fil ter i t L actat e o f iro n i s o ft e n o n l y p ar t i all y s ol u ble i n

.

w at e r b u t t h e sy r u p aid s i t s s ol u t io n
, If i t re fu se s t o .

e n t ir e l y di ss ol v e t here w ill be a defi c ie ncy O f t hi s s u b

,

s tan c e .

The foregoi ng e li xi r acq u i red w e are t old co n sidera , ,

ble rep u tat io n i n Fran ce w here i t w as de v i s ed b y ,

Ro b i n eau d o f B ordeau x an d w h o fi nall y p u bli shed

,

t h e for m u l a ( S e e .P ro c eedi n g s o f t h e A m eri ca n Ph ar m a

c eu t i cal A ss o cia t io n 1 8 71 p , , .
 ELI X IR F O R M U LJE .

EL IXI R O F C H L O R I D E O F I R O N W ITH AM M O N IU M
CI TRATE AN D G EN TIA N .

( Eu xm OF GE N T N IA A ND I R N
O . F E R R T E D EL X R
A I I OF GE N T IAN .
)

F l u i d E x t ra c t Of G e n t i an flu i d ou n c e

S o l u t i on of C i t ra t e of A m m on i u m
T i n c t u re o f C h l ori d e O f I ron
S i m p l e E l i x i r , C arb o n at e Of M ag n es i u m , D i s t i l l ed
W a t er , o f e a c h a s u ffi c i en t q u an t i t y .

Tri t u r at e t h e fl u id ex t ract o f ge nt i an i n a m or tar w i t h ,

carbo n at e o f m ag n e s i u m i n am o u n t s u ffi c ie n t t o for m a

t hi c k p as te an d t he n grad u all y ad d fo u r fl u id o u n c e s o f
,

di st ill e d w at e r an d fil t er M i x t h e t i nct u re o f c hloride O f

.

i ro n w i t h {h e sol u t io n O f c i t rat e O f am m o n i u m an d add to

t h e pr e cedi n g fil t r at e an d t he n add O f s i m ple e li xir a
,

s u ffi c ie n t am o u n t t o m ake t h e w hole m e as u re s ix t ee n

fl u i d o u n ce s .

Each fl u id drach m ( t e as poo n fu l ) O f th e fi n i shed e lixir

co n tai n s abo u t t w o m i n i m s e ac h O f t i n ct u re o f c hloride O f

iro n an d fl u id ex t ract O f ge n t i an The c i t rat e o f am m o .

n i u m i s i n t rod u ced t o pre v e n t bl ack e n i n g o f t h e elixir ,

as expl ai ne d u n der elixir o f cali say a an d c hloride O f i ro n

w i t h c i t r at e o f am m o n i u m " .

Elixi r O f ge n t i an an d chloride O f iro n w as m e n t io n ed

fir st i n t h e D m gg zkts Ci r cul ar 1 8 71 and after w ar d ’

, ,

( 7 )
1 8 3 Pro f J o s eph R. e m i n g t o n pre s e n t ed a pro c e s s t o

t h e Amer i can j our na l of P l z ar macy The N ew ark Ph ar .

m ace u t i cal A sso c i at io n ( 1 8 71 ) r e c o m m e n d e d an elixi r O f

ge nt i an an d p e p h O s p h at e o f iro n and at a st ill e arlier ,

d at e M r Willi am B Tho m p so n h ad p r e sen t ed a pro ce ss

. .

fo r t hi s elixir t hro u gh t h e D r ugg zlrzs Ci rcu l ar

’
.
,

The s
ugg est i o n m ad e b y t h e D r ugg z s ts Ci r cu l a r ( 1 8 76) t h at M r C r eu se s
w as
’ ’ ’

Ti i i
.

T as t e le ss n c u r e o f I r o n ( s o l u t i o n o f c h l o r d e O f i ro n w i t h c i t r a t e o f amm o
t u m) be
n
i i
u s e d , m c o n n e c t o n W t h g e n t i an , t o p
r ev e n t p r ec i i t at i o n an d t h e bl acp d sc ol o ra k i
i
t on .
 1 08 E LI X IR F o R M U L ac .

EL I X I R O F C H L O R I D E O F I R O N W I TH H Y D RO C H LO
R AT E O F QU I N I N E AN D A R S EN I O U S A C I D .

( Bu xi n o r I R N Q
O , u mu A ND A R EN C )
S I .

H y d roch l orat e of Q u i n i n e 64
S ol u t i o n A rs en i ou s A c i d ( U S P
of . . .
, 1 88 3 ) 1 28

S i m pl e El i x i r 1 5 flui d o u n c es

T i n c t u re of C h l ori d e of I ron 1

H y d roc h l ori c A ci d a s u fli c i en t
, q u a n t i t y .

Tri t u ra t e t h e h y dro ch lorat e o f q u i n i n e i n a m ortar

w i t h fo u r fl u id o u nce s o f s i m ple elixir an d ad d O f h y dro ,

c hlo ri c a c i d an a m o u n t s u ffi c ie n t t o e ffe ct i t s s ol u t io n ;

the n ad d t h e re m ai n der o f t h e s i m ple eli xir and t h e o t h e r

i ngredie n t s F il t er i f n e ce ssar y
. I f h y d ro chlorat e o f .

q u i n i n e can no t be O b tai n e d u se q u i n i ne alk aloid i n st ead

, ,

and h y dro chlori c a c id e n o u gh t o di ss ol v e i t .

Each fl u id drach m ( t e as poo nfu l ) O f t h e fi n i shed elixir co n

t ai ns abo u t t hree an d o n e h alf m i n i m s o f t i n ct u re o f chloride
-

o f i ro n o n e hal f grai n o f h y d ro c hlora t e O f q u i n i n e an d

,
-

o n e m i n i m O f O ffi ci nal s ol u t io n o f ar se n i c .

O ur for m u l a i n t rod u ce s t h e h y dro chlorat e o f q u i n i n e ,

ch lor i d e o f iro n an d s ol u t io n o f ar s e n io u s a c id i n h y dro

c hlo ri c ac id Too great cau t io n can no t be e m ploy ed t o

.

pr eve nt th e pre ci p i ta t io n O f arse ni c and b y us i ng h y dro ,

ch lori c a cid t hi s t e n de n cy t o s epara t io n i s a v oi ded .

E L I XI R F P R O T O -C H L O R I D E O F I R O N
O .

( EL1x 1 R OF F E RR U O S C HL R D E )
O I .

S u l p h at e I ron , C ry s t al l i z
of ed 2 56 grai ns

B i c arb on at e of S od i u m
H y d roc h l ori c A ci d S i m p l e E l i x i r
.
, D i s t i l l ed W at er, of each
a s u ffi c i en t q u a n t i t y .

D i ss ol v e th e su lph at e o f iro n and b i carbo nat e o f sod i

u m s ep arat el y , each i n six t ee n fl u id o unces of di st ill ed
 IO E LI XIR F O R M U LIE .

prec ipi tat e an d w as h i t u n t il n e arl y free fro m chloride o f

cal c i u m .

D i ssol v e t h e m ag m a prod u c ed b y t h e foregoi n g opera

t io n i n eigh t fl u id o u n ce s O f s i m ple el i xir b y t h e ai d o f ,

t h e c i t r at e O f po tass i u m an d t he n ad d e n o u gh s i m ple
,

elixi r t o bri ng t h e w hol e t o t h e m easu re o f s ix tee n fl u id

o u nce s .

Each fl u id d rach m ( t easpo o nfu l ) O f t h e fi n i s hed e li xir

c o n tai n s t hree fo u r t h s o f a gr ai n o f fe rri c h y p o p h o s
-

p h i t e
. Thi s i m pro v ed m e t h od fo r m aki ng s ol u t io n o f

h y popho s ph i te o f i ro n w as i nt rod u ced by Pro f C L ew i s . .

D iehl i n a p aper re ad be fore t h e K e n t u ck y Ph arm ace u t i

cal A ss o c i at io n 1 88 2 , The origi n al w as n o t i n o u r p os
.

s e ss io n ,an d w e re ce i v e d t h e ab s t r ac t p re se n t ed i n t h e

pro ceedi ng s o f t h e A m e ri can Ph ar m ac e u t i cal A sso c ia

t io n j u s t i n t i m e t o i n ser t t h i s o n e for m u l a .

E L I XI R O F I O D I D E O F I R O N W I TH IO D ID E O F Q UI
N IN E .

( E LXR
I I OF l o om s O F I R N O AND Q um m .
)
I od i d e of I ron 1 6 g ra i n s

I od i d e of Qu i n i n e 1 6
S i m p l e El i x i r 1 6 fl ui d o u n c es

Tri t u rat e t h e iodid es i n a m or tar w i t h t h e s i m ple elixir ,

addi n g a l i t t l e h y driodi c ac id if n e c e ssar y an d w he n ,

t he y are di s sol v ed fil t er i f de s irable

, , .

Eac h fl u id drach m ( t easpoo n fu l) o f t h e fi n i s hed elixir

c o n t ai n s o n e eigh t h gr ai n e ac h o f iodide o f i ro n an d o f
-

iodide O f q u i n i n e Th i s for m u l a w as an no u n ced i n t h e

.

D l Ci rcu l ar ,
’

gg
r u z rts 1 8 67 .
 ELI XIR F O R M U LE . I I I

E L I X I R O F L A C TA T E O F I R O N .

L a c t ate of I ro n 2 56 g rai n s
L a c t i c A ci d , S i m p l e E l i x i r , o f e ac h a s u ffi c i e n t q u a n t i t y .

Tri t u rat e th e l actat e o f i ro n i n a m or tar w i t h fo u r t e e n

fl u id o u nc e s O f s i m pl e elixir and ad d o f l act i c aci d a q u an
,

t i ty s u ffi c ie n t t o re n der t h e liq u id d i st i n ct l y ac id ; t he n
ad d e n o u gh s i m ple elixir t o b ri n g t h e w hole t o t h e m e as

u re o f s ix t e e n fl u id o u n ce s an d fil t er , .

Each fl u id drach m ( t e aspoo n fu l ) O f th e fi n i shed el i x i r

c o n tai n s t w o gr ai n s o f l ac tat e o f i ro n .

E L I X I R O P L A C TA T E O F I RO N W I TH P EP S IN .

El i xi r of L a c t at e Of I ron 8 flu i d ou n c e s

El i x i r Of P ep s i n . 8

M i x t he m t oge t her .

E ach fl u id d rach m ( te aspoo n fu l ) o f t h e fi n i shed eli x ir

c o n tai n s t w o grai n s e ac h O f la ct a t e o f iro n an d sacc h arat e d

p ep s i n .

EL I XI R O F P H O S P H A T E O F I R O N .

P h os p h at e of I r on , S ol u b l e (U S P
. . .
, 1 88 3 ) 1 28 g rai n s
S i m p l e El i x i r 1
o
. 12 flui d o u n c es

D i s t i l l ed W at e r 4

D i ssol v e pho sph at e o f iro n i n t h e di st illed w at er

the ,

an d ad d t h e s i m ple elixi r .

E ach fl u id d rach m ( t e as poo n fu l ) o f t h e fi n i shed elix i r

c o n tai n s o n e grai n o f pho sph at e o f iro n .
I I2 ELI XIR F O R M U LJE .

E L 1x 1 R O F P H O S P H A T E O F I RO N W I TH P H OS P H A T E
0T QU I N I N E .

( Eu x m‘ s H
P OS P H T
A IR N
E OP O A ND Q u rN rA .
)
El i xi r o
f
P h o s p h at e of I ro n . 8 flu i d o u n ces

El ix i r of P h os p h at e of Qui n i n e 8

M i x t he m t oge t her .

Each fl u id drach m ( t e aspoo nfu l ) o f t h e fi n i sh ed el i x 1r

c o n tai n s o n e h al f gr ai n e ach o f pho s ph at e O f iro n an d
-

pho sph ate o f q u i ni n e .

EL I XI R O F P H O S P H ATE O F I R O N W ITH P H O S P HA TE
OF QU I N I N E A N D S T RYC H N I N E .

( Eu xi R O F P H S H TE O P A OP I R N QU N
O ,
I IA AND S T RYCHN I A. )

El i x i r of P h os p h at e of I ron an d Qu i n i n e 1 6 flu i d ou n ce s

S t ry c h n i n e g rai n s
A c et i c A c i d , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e st ry ch n i n e i n a m or tar w i th ace t i c aci d ,

i n am o u n t s u ffi cie n t t o e ffe ct i t s s ol u t io n an d t he n ad d ,

t h e elixir Fi l t er i f n e ce ssary
. .

Each fl u id drach m ( t easpoo n fu l) o f th e fi n i shed elixir

c o n t ai ns o n e h al f gr ai n e ach O f pho sph at e s O f iro n and
-

q u i n i n e an d o n e fi fti eth o f a grai n o f st r y ch n i n e

,
-
.

I n 1 8 71 M r J C r eu se co n t rib u t ed an ar ti c le t o th e
. .

D r ugg i sts Ci rcu l ar regardi ng a prep arat io n sold u n der t h e

’

n am e o f t h e foregoi n g elixir an d w h i ch pro v ed t o b e an ,

elixir o f py rop/zosp lz ate of i ron I t i s al s o t r u e t h at o t her .

prep arat i o n s con tai n i ng p y ropho sph at e o f i ro n are so m e

t i m e s d i s pe n sed w here pho s ph at e i s s p e c i fi ed an d p h y ,

s i c i an s sho u ld be care fu l an d u se t h e abbre v i at io n fi l m s .

o n l y w he n t h e pho sph at e i s de si re d .
 E LI XIR F O R M U L/E .

w ill fi n d t h at o n s iderable skill i s n e c e ssary t o m ake pre

c

se n tab l e an d rep u table prep ar at io n s an d o ft e n s o m e o f

,

t h es e co m bi n at io n s are v er y t r y i ng t o t h e p at ie n c e O f t h e
operat or The re ader i s re ferred t o o u r re m ark s u nder
.

t h e he ad of pep si n an d elixir s o f cal i say a b ark an d t h e

alk aloid s .

EL I XI R O F P YR O P H O S P H A T E O F I R O N .

P y rop h os p h at e of I ron 2 56 g ra i n s
D i s t i l l ed W at er 2 flu i d o u n ces

S i m p l e E l i x i r, a s u ffi c i en t q u an t i ty .

D i ssol v e t h e p y ropho sph at e i ro n i n t h e d i st i lled w a

of
°
t er b y t h e ai d o f a he at n o t ex ceedi ng 1 8 0 F
, an d add .
,

t o t h e sol u t io n e n o u gh s i m pl e e lixir t o bri ng t h e w hole

t o t h e m e as u re o f six t ee n fl u id o u n ce s and fi l t e r i f n ec ,

e ssar y I f i t h as an aci d re act io n n e u t ralize or e v e n

.
,

re nder i t sl igh t l y alk al i n e b y m ean s O f am m o n i a w at er .

E ach fl u id d rach m ( t easpoo n fu l ) o f t h e fi n i shed elixi r

c o n tai n s t w o grai n s O f p y ropho s ph at e o f iro n Th i s pro .

ce ss i s e ss e n t i all y t h at adop t e d b y t h e A m eri can Ph ar

m ace u t i cal A ss o c i at io n T h e for m u l a fo r elixir o f

p y ropho sph at e o f iro n adop t ed b y t h e J oi n t C o m m i tt ee
,

O f t h e M edi cal an d Ph ar m ace u t i cal A ss o c i at io n s o f t h e

D i s t ri c t o f C ol u m bi a c o n tai n ed 3 2 0 grai n s o f
py
r o p h o sp h at e o f iro n i n t w el v e fl u id o u n c e s o f t h e fi n i she d

elixir .
 ELI XI R F O R M U LIE . 1 1 5

EL I XI R O F P YRO P H O S P H A T E O F I RO N W I TH B IS
M U TH A N D P EP S I N .

( Eu x xR O F A C rr R A r E
M M O N ro-
'
OR B M UTH
IS wn n P E PS i N A ND I R N
O . Eu xtR O R

P E N
PS I , 8 15 14 0 7 11 AND I R N)
O .

El i x i r of P y rop h os p h at e of I ro n 8 flui d ou n c e s

El ix i r of C i t rat e of A m m on i u m an d B i sm u th w i th
P ep s i n 8

M i x t he m t o ge t her .

Each fl u id drach m ( t easpoo n fu l) o f t h e fi n i shed elixir

c o n t ai n s o n e gr ai n o f p y ropho sph at e O f i ro n an d o n l y

o n e h al f gr ai n e ach O f p e p s i n an d o f a m m o n io c i t rat e o f
- -

bi sm u th The sol u t io n h as an alk ali n e re act io n and t h e

.

ep i n n der t h c o n di t io n s i s o f u n c er tai n q u ali ty

p s u ,
e ,
.

EL I XI R O F P YRO P H O S P H A T E O F I RO N W I TH CIN
CH O NID INE .

( Eu x1 R OR I R N
O A ND C 1 N C HO N 1D 1A . )

El i x i r of C i n c h on i d i n e 8 flui d ou n c es

El i x i r of Pe p h O S p h at e of I ron 8

M i x t he m t oge t her he n grad u all y add o f am m o n i a

, an d t

w at e r o r ac e t i c ac id an am o u n t s u ffi c ie n t t o re n der t h e
, .

liq u id o f n e u t ral re act io n and t ran s p are nt ; t he n fi l ter i t

i f n e ce ssar y .

Each fl u id drach m ( t e aspo o n fu l) o f th e fi n i shed elixi r

c o n tai n s o n e grai n O f p y ropho s ph at e o f iro n an d o n e h al f -

grai n o f ci ncho n id i ne The re m ar ks c o n cern i ng elixir

.

o f p y ropho sph at e o f i ro n w i t h s t ry c h n i n e are adap t ed t o

t hi s prep arat io n .
 1 16 ELI XIR F O R M U LE .

‘
E L 1 x 1 R O F P YR O P H O S P H A T E O F 1 R O N wn H CIN
C H O N I D IN E A N D S T R YC H N I N E .

( Eu x 1R O F I R N O , CI NCH N DO I IA A ND S T RY C H N IA .
)
S t ry c h n i n e 2
x g rai ns

El i x i r of P y rop h os p h at e of I ron w i t h C i n c h on i
dine 1 6 fl ui d ou n c e s

A c et i c A c i d , a s u ffi c i e n t q u an t i t y .

Po w der th e st r y ch n i n e and grad uall y add ace t i c ac id

u n t il i t i s di ssol v ed t he n m i x w i t h t h i s sol u t io n th e
,

elixir o f py ropho sph ate O f iro n w i t h ci ncho n id i n e E ac h .

fl uid drach m ( t e aspoo n fu l) o f t h e fi n i shed elixir co n tai n s

o n e gr ai n O f p y ropho s p h at e o f iro n ace tat e o f ci n ch o ni ,

di n e eq u i v ale nt t o o n e h al f grai n o f ci n cho n idi n e and one

-
,

fi fti et h grai n o f a ce ta t e o f st ry c h n i n e .

EL IXI R O F P YRO P H O S P H A TE O F I RO N W I TH Q UI
N I N E, C I N C H O N I D I N E A N D S TR YC H N I N E .

( Eu x m OF I R N QU N
O ,
1 1A, C rN C H O N rD rA A N D S T RY C H N IA .
)
El i x i r of Pe p h O S p h ate of I ron w i t h Qu i n i n e 8 flu i d ou n ces

El i xi r of P y rop h osp h at e of I ron w i t h C i n c h on i d i n e . . 8

S t ry c h n i n e g rai n s
A c et i c A c i d , a s u fli c i e n t q u a n t i ty .

M i x t h e elixi rs , an d
ry ch n i n e p rev io u sl y di s
add th e st

s ol v ed b y t ri t u ra t io n w i t h a su ffi c ie n t am o u n t o f ac e t i c

ac id . E ach fl u id drac h m ( t easpoo n fu l ) o f t h e fi n i she d

elixir co n tai ns o n e fo u r t h g rai n ci n cho n idi ne an d o n e h al f
- -

grai n q u i n i ne as th e ace tat e s o f t he se alk aloid s o n e grai n

, ,

O f p y roph o s pha t e o f i ro n an d o n e fi ft i eth o f a grai n o f

,
-

st r y c h n i n e .
1 18 ELIX I R F O RM U L E .

1 60 grai ns p y ropho sph at e o f iro n t o t h e pi n t A s 2 56

Of .

grai ns i s th e accep ted am o u n t O f t h e A m eri can Ph ar m a

c e u t i cal A ss o c i at io n w e e m plo y t h at propor t io n
, .

E L I XI R O F P YR O P H O S P H A T E O F I R O N W IT H Q UI
N IN E A N D CINC HO N ID IN E .

“ ha m or I R N O , Q u rN 1 A A N D C 1 NC NO N 1D 1 A .
)

El i x i r of Pe p h os p h a t e of I r on w i t h Qu i n i n e 8 flu i d ou n c e s

El i x i r of P y rop h os p h at e of I ron w i t h C i n c h o n i d i n e . . 8

Mix t he m t oge t her .

Each fl u id drach m ( t e aspoo n fu l) O f th e fi n i shed eli x ir

c o n tai n s t w o grai n s o f p y ropho s ph at e o f iro n an d t h e

eq u i v ale nt o f o ne h al f grai n O f q u i n i n e an d o n e fo u r t h
- -

grai n o f c i ncho n idi ne as t h e ace tat e s o f t he s e alk aloid s

, .

E L I XI R O F P YR O P H O S P H A T E O F I RO N W ITH Q UI
N IN E AND CIN C HO NIN E .

( EL1 x 1 R OF I R N QU N
O ,
1 1A AND C 1N C H O N 1 A .
)

El i x i r of Pe p h o s p h at e of I ron w i t h Qu i n i n e 8 flu i d ou n c e s

El i x i r of P y rop h os p h at e of I ron w i t h C i n c h on i n e 8

M i x t he m t oge ther .

Each fl u id drach m ( t e aspoo n fu l) o f t hi s eli xir co n tai n s

t w o grai n s o f p y ropho s pha t e O f iro n an d t h e eq u i v ale n t
o f o n e h al f grai n O f q u i n i n e an d o n e fo u r t h grai n o f c i n
- -

ch o n i n e as t h e ace tat e s O f t he s e alk aloid s .

 ELI X IR F O R M U LZE . 1 19

EL I X I R O F P YR O P H O S P H A T E O F I R O N W I TH Q UI
N I N E, C I N C H O N I N E A N D S T RYC H N I N E .

( EL1 x 1 R OF I R N QU N
O ,
1 1A, CI NCH N O IA AND Se cu m A
I
.
)

El ixi r of Pe p h os p h at e Of I r on w i t h Qu i n i n e an d

C i n c h on i n e 1 6 flu i d o u n c es

S t ry c h n i n e g r a i n s

A c et i c A c i d , a s u fl i ci e n t q u a n t i ty .

Tri t u rat e t h e st ry ch n i n e i n a m or tar w i t h e no u g h ,

ac e t i c ac id t o e ffe ct i t s s ol u t io n t he n m i x t hi s w i t h t h e ,

e lixir .

Eac h fl u id drach m ( t e aspoo n fu l) o f t h e fi n i shed elixi r

c o n tai n s t w o gr ai n s o f p y ropho s ph at e o f i ro n an d t h e

eq u i v ale nt O f o ne h al f grai n o f q u i n i ne an d o n e fo u rt h
- -

grai n o f c i nc ho n i n e as t h e ace tat e s o f t he se alk aloid s and ,

o n e fi ft i et h o f a grai n o f ace tat e O f s t r y ch n i n e

-
.

E L I X I R O F P YR O P H O S P H A T E O F I R O N W I TH Q UI
N IN E AN D S T RY C H N I N E .

( Eu xm o r I R N O , Q l 'l N l A A ND ST Y C H N I A ) .

S t ry c h n i n e 2
% g rai n s
El i x i r of P y rop h os p h at e of I ro n w i t h Qu i n i n e 1 6 flu i d ou n c e s

A c et i c A c i d , a s u ffi c i e n t q u an t i t y .

Po w der t h e st ry ch n i n e an d t ri t u rat e it w i t h su ffi cie nt

a ce t i c acid t o e ffect i t s s ol u t io n M i x t h i s w i t h t h e .
,

elixir o f p y ropho sph at e o f iro n w i t h q u i n i n e Each fl u id .

drach m ( te as poo n fu l ) o f t h e fin i shed e lixir co ntai n s o n e

fi fti et h O f a grai n o f s t r y c h n i n e o n e gr ai n O f q u i n i n e an d ,

t w o gr ai n s o f p e p h o s p h at e O f iro n I t agree s i n pro .

por t io ns w i t h t h e for m u l a adop t ed b y th e A m eri can Ph ar

m ace u t i cal A sso ci at io n 1 8 75 , .
 ELI X I R FO R M U LE .

1 60 grai ns p y ropho sph at e o f iro n t o t h e pi n t A s 2 56

of .

grai ns i s t h e accep t ed am o u n t o f t h e A m eri can Ph ar m a

c e u t i cal A s s o c i at i o n w e e m plo y t h at propor t io n
, .

E L I XI R O F P YR O P H O S P H A T E O F I R O N W IT H Q UI
N IN E A ND CIN C HO N ID IN E .

( Eu xi R O F I R N O , Q L1 N1 A
'
A ND C 1 N C H O N 1D 1 A .
)

El i x i r of P y rop h os p h at e of I ro n w i t h Qu i n i n e 8 flu i d ou n c e s

El i xi r of P y rop h os p h a t e of I ron w i t h C i n c h on i d i n e . . 8

M ix t he m t oge ther .

E ach fl u id drach m ( t easpoo n fu l) O f th e fi n i s hed eli x ir

c o nt ai n s t w o grai ns o f p y ropho s ph at e O f iro n an d t h e

eq u i v ale nt o f o ne h al f grai n o f q u i n i ne an d o ne fo u r t h
- -

grai n of c i ncho n idi n e as t h e ace tat e s o f t he se alk aloi d s

, .

E L I XI R O F P YR O P H O S P H A T E O F I R O N W I TH Q U I
N IN E AN D CI N C HO NI N E .

( Eu x m OF I R N QU N
O ,
1 1A A ND C 1N C H O N 1 A .
)

El i x i r of P y rop h os p h at e of I r on w i t h Qu i n i n e 8 flu i d o u n c es

El i x i r of P y rop h os p h at e of I ron w i t h C i n c h on i n e 8

M i x t he m t oge ther .

Each fl u id drach m ( t e aspoo n fu l) o f t h i s eli xir co n tai n s

t w o grai ns o f p y ropho spha t e o f iro n an d t h e e q u i v ale n t
o f o ne h al f grai n o f q u i n i n e an d o n e fo u r t h grai n o f c i n
- -

c h o n i n e as t h e ace tat e s O f t he s e alk aloid s .

1 20 E LI XIR F O R M U Ll E .

EL I X I R O F P YRO P H O S P H A T E O F I R O N W I TH V A LE
R IA N AT E O F
'
Q U I N I N E A N D A C ETA T E
O F S T RYC H N I N E .

( E1 1 x 1 R
. OF V A L E R N T E QU N W T H I R N
IA A OF S T RYCHN
I IA I O AND IA )
.

V al e ri an at e of Qu i n i n e g ra i n s

P y rop h os p h at e of I ron
S t ry c h n i n e
S i m p l e El i x i r 1 6 flu i d ou n c e s

A cet i c A ci d , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e st ry ch n i n e i n a m or tar w i t h ace t i c ac id

i n am o u n t s u ffi c ie n t t o e ffe ct i t s s ol u t io n t he n ad d t h e ,

v al eri ana t e o f q u i n i n e an d fo u r fl u id o u n c e s O f s im ple

elixir an d t ri t u rat e u n t il t h e v aleri anat e i s di ss ol v ed .

S ho u ld t h e v aleri an at e o f q u i n i n e fai l t o di ssol v e aft er

a m oderate t i m e ad d a li tt le ac e t i c ac id L ast l y di ssol v e .
,

th e p y ropho sph ate i n t h e re m ai nder o f t h e s i m ple elixi r ,

an d m i x t h e s ol u t io n s .

Each fl u id d rach m ( t e aspoo n fu l) O f th e fi n i shed e l ixir

co n t ai n s o n e grai n e ach o f t h e v aleri anat e o f q u i n i n e an d

p y ropho sph at e O f iro n an d o ne fi ft i e th grai n O f st ry c h

,
-

n i ne .

Th i s for m u l a c orre spo nd s regardi ng proport io n s w i t h , ,

o n e O ffered b y t h e D rugg i sts Ci rcu l ar 1 8 71 ex cep t i n g

’

, ,

t h at o u r s c o n tai ns h al f t h e am o u n t O f p y ropho sph at e o f

ir o n .

E L I XI R O F P YR O P H O S P H A T E O F I R O N W I TH P EP S I N .

( Eu x rR O F I R O N AND P E N
PS I . F E RR T E D
A Eu xm OF E SN)
P P I .

El i x i r Of P y rop h os p h at e of I ron 8 flu i d ou n c e s

El i x i r Of P ep s i n 8

M i x t h e m t oge th er e u t ral or o f s ligh t l y al

,
an d i f no t n

k ali n e re act i o n cau t io u s l y add amm o n i a w a t er u n t i l i t

,

w ill ch ange bl u e li t m u s p aper t o red .

 ELI XIR F O R M U L ZE . 2 I

Eac h fl u id d rach m ( t e aspoo nfu l) o f th e fin i shed elixir

c o n tai n s o n e grai n eac h o f p y ropho spha t e o f i ro n an d

su ch a m od ifi cat io n o f pep s i n as can exi st u n der t h e c o n

d i t i o n s n e c e ssary t o for m t h e el i xir .

E L I XI R O F P YRO P H O S P H A T E O F I RO N W IT H P EP S I N .
B I S M U TH A N D S T RYC H N I N E .

( Bu x I R or I R N PE N
O , PS I , B IS M UTH AND S T RYC H N IA. Eu xIR O P P E N
PS I , B IS M UTH ,

S T RY C H N IA AND I R N)
O .

El i xi r of P y rop h os p h at e of I ron 8 flu i d o u n ces

El i x i r of A m m on i o-C i t rat e of B i sm u t h an d P ep s i n 8 .

S t ry c h n i n e
A c e t i c A ci d , a s u ffi ci en t q u an t i t y.

Tri t u rat e t h e st rych n i n e i n a m ortar w i t h a ce t i c acid ,

su ffi c ie n t t o di ssol v e i t and t he n add t h e elixir s h av i n g

, ,

pre v io u s l y m ixed t he m t og e t her .

Each fl u id drach m ( t e aspoo nfu l ) o f th e fi ni shed elixir

c o n tai n s ( s u bje ct t o re m ark s w hi ch follo w ) o n e grai n O f

p y ropho sph at e O f iro n and o n e h al f grai n e ach o f am m o -

n i O c i t rat e
-
o f bi sm u t h an d o f pep s i n and o n e fi ft i e th ,
-

grai n o f st ry ch n i n e .

Th i s m ix t u re l i ke man y ot hers w e h av e bee n led t o

,

c o n s ider i n t h i s w ork r e m i n d s u s o f th e p ol y p harmacy

, e

O f old e n t i m e s ex cep t i n g t h at t h e c o n st i t u e n t s are n e w

, .

I n co ns id eri n g i t w e m ust a ccep t t h at t h e pep s i n h as n o

v al u e as a t herape u t i cal age n t u n le s s i t s ac t io n i s s i m pl
y
s u spe nded b y th e alka l i n e nat u re o f th e elixir .
 ELl R F O R M U LAZ. ‘

EL I X I R O F P Y R O P H O S P H A T E O F I R O N W IT H P EP S I N
AN D S T RYC H N I N E .

(E LXR
I I or I R N
O , P R Ps I N AND S T RYC H N IA Bu xi n or P E N
PS I ,
-
I RO N AND S T RY C H

El i x i r of Pe p h o s h
p at e of I ron w i t h P ep si n 1 6 flu i d ou n c e s

S t ry c h n i n e 2
% g rai n s
A c et i c A c i d , a s u ffi c i en t q uan t i ty .

Tri t u rat e t h e st ry ch n i n e i n a m or tar , w i t h ac e t i c acid

in s u fli c i e n t am
o u nt t o e ffe ct i ts s ol ut io n an d t he n ad d ,

t h e e l ixir o f p y ropho sph at e o f iro n w i t h pep s i n .

Ea ch fl u id dra ch m ( t e aspoo n fu l ) o f t h e fi ni shed e l i x i r

co ntai ns o n e grai n e ac h o f p yropho sph ate o f iro n an d o f

pep si n an d abo u t o ne fi ft i et h O f a g rai n o f stry ch ni n e

,
-
,

as t h e a c e tat e o f t ha t alk aloid .

EL I X I R O F P Y R O P H O S P H A T E O F I R O N A N D S T RY C H
N IN E .

( Eu x xR o r I R N
O A ND ST v n m A .)

a}; g rai n s
El i xi r of P y rop h os ph at e of I ro n 16 flui d ou n c e s

A cet i c A ci d , a s u ffi c i en t q u a n t ft y .

Pow d er
°

h i e and g rad u al l y ad d acet i c a ci d

r
t h e st y c n n

and tri t u rat e u n t il a c le ar s ol u t io n re su l ts M i x t hi s .

w i t h t h e elixir o f p y ropho sph at e O f iro n an d i f n o t o f ,

n e u t ral re act io n add ac e t i c ac id or a m m o n i a w a t er t o

n e u t ralizat io n .

Each fl u id d rach m ( t e as poo n fu l ) O f t h e fi n i sh ed elixi r

c o nt ai ns t h e fi ft ie t h of a gr ai n o f st ry ch n i n e i n t h e for m .

o f a ce t at e O f s t r y c h n i n e w hi c h i s t h e,propor t i o n adop t e d
b y t h e A m eri can Ph ar mace u t i cal A ss o c i at io n 1 8 75 , .

O u r e x perie nce i s d ec id e dl y i n fav or o f ac e t i c ac id fo r

m ak i ng th e sal ts o f al l alk aloid s w hi ch are t o b e ass o cia
1 24 E LI X IR F O R M U LA
E .

EL I XI R O F J A B O RA N D I .

F l u i d Ex t ract of j ab oran d i 2 flui d ou n ces

S i m p l e El i x i r
A l co h ol
C arb on at e Of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u r at e t h e fl u id ex t ract o f j aboran di i n a cap aci o u s

m or tar w i t h carbo n at e o f m ag ne s i u m i n am o u n t s u fli
,

c ie nt t o for m a c r eam y m ix t u re ; t he n grad u all y add t h e

s i m ple elixir s t irri ng w ell

, an d fil t er L ast l y m i x th e
,
.
,

fil t rat e w i t h th e al cohol .

Each fl u id drach m O f t h e fi n i sh ed elixir w ill co n tai n

t h e m edi c i nal pri n c iple s o f s e v e n and a h al f m i n i m s o f
fl u id ex t ract o f j abo rand i .

K L EI N S S TO M A C H I C EL I XI R
’
.

( EL1 x 1 R V 1 S C E R A L E K L E I Nn ) .

E x t rac t C ard u u s B en e d i c t u s 1 t roy ou n c e

E x t rac t E ry t h ra a C en t au ri u m 1

E x t ract G en t i an I

T i n ct u re B i t t er O ra n g e P e el 20 flui d ou n c e s

M al ag a W i n e

Pl ace th e ex t racts i n a m or tar an d bri ng t he m t o a

c re am y co n s i s t e n ce b y t ri t u rat io n w i t h s u cc e ss i v e add i ,

t io n s o f s m all am o u n t s o f w i n e t he n s t ir i n t h e re m ai n
der o f t h e w i n e an d ad d t h e t i n ct u re O f orange peel an d ,

fil t er .

( F r om t h e n o n-O fli c i n al For m u l a ry of th e D u t ch Soc i et y fo r th e A d v an c em en t of

P h ar m ac y .
)

EL I X I R L A C T O P E P T I N .

Lact o p ep t i n i s pri v at e prop e r t y U nder t hi s n am e a

.

p re p arat io n h as bee n i nt rod u ced and ex te ns i v e ly ad v er

 EL I XI R F O R M U LZE . 125

t i z ed , an d t h ro u gh o u r te sy t o t h e righ t fu l o w ner s w h o
c .

“
l o make
a s an Elixi r o f Lacto p ep t i n w e re frai n fro m
,

i n ter feri ng .

‘
5

EL I X I R O F LA C TU CA R I U M .

2 56 g rai n s
16 flu i d o u n c es

Tri t u rate t h e l ac t u car i u m w i t h t h e si m ple eli xir allo w ,

t h e m ix t u re t o re mai n i n a c o v ered v e ss el fo r t w e n ty fo u r -

h o u rs sh aki ng o ccas io nall y t he n fil ter i t

, , .

Each fl u id drac h m ( t ea spoo nfu l) o f t h e fi ni shed elixir

co n tai n s t h e proper t i e s o f t w o grai n s o f l ac t u cari u m .

L A X A T IV E E L I X I R .

F l u i d Ex t ract of R h u b arb flu i d ou n ce

F l u i d E x t ra c t Of S en n a
F l u i d E x t ra c t of T arax a c u m
F l u i d E x t ra c t of B u c k t h orn B ark 54
F l u i d E x t ra c t Of G i n g er 4
1
[

R oc h el l e S a l t 1 t roy ou n ce
S i m p l e El i x i r 14 fl u i d o u n ces
C arb on at e of M a g n es i u m , a s u fli c i e n t q u an t i ty .

Tri t u rat e t h e fl u id ex t ract s ( h av i ng pre v io usl y m ixe d

t he m t oge t her) i n a cap ac io u s m or tar w i t h carbo nat e O f ,

m ag ne s i u m i n am o u n t su ffi cie n t t o for m a c ream y m i x

t u re ; t h e n grad u all y ad d t h e s i m ple elixir st irri n g w ell , ,

an d fil t er .La st l y di ssol v e i n t h e fil t rat e t h e Ro c hel l e

,

sal t .

Thi s elixi r i s abo u t like t h at o f M r R W G ard n er as . . .

,

p u bli shed i n th e Pro ceedi ngs o f t h e A m e ri can Ph ar m a

ce u t i cal A sso c i at io n 1 8 8 0 ex c e p t i ng t h at w e h av e o m i t
, ,

t ed pho s ph at e an d bi carbo na t e o f s odi u m .

1 26 EL I X IR F O R M U LIE .

LERO Y S P U R G A T I V E E LI X I R
’
.

S ca m m o n y g rai n s

T u rp et h R oo t 6O
J al ap 480
D i l u t ed A l coh ol 1 6 flu i d o u n c es

M acerat e t h e dr u g s ( o ar sel y p o w dered

) icn t h e al c oh o l
for t w el v e ho u r s and i n a w ar m lo cat io n and fil t e r
, , .

M i x t h e fil t rat e w i th a sy r u p m ade as follo w s :

S e n n a , b r u i s ed g ra i ns

B oi l i n g W at er 4 fluid ou n c e s

S u g ar t roy ou n c es

I nfu se th e s e n na i n th e boil i ng w at er s t rai n and d i s

,

s ol v e t h e s u gar i n th e liq u id Thi s for m u l a w as p u b

‘

l i sh ed i n t h e D m gg i rts Ci r cu l ar
’

, 1 8 75 .

“
The abo v e e lixir m u st n o t be c o nfo u n ded w i th Le
ro y V o m ito P u rg at i v e Elixir
’
s -
.

L ER O Y S VO
’
M I T P U R G A T IV E E L I X I R
O -
.

F l u i d Ex t rac t of S en n a 1
X fl uid o u n ces

T art ar Em e t i c 20
g ra i n s

W h i te W ine 1 6 fluid ou n c es

Tri t u rat e th e fl u id ex tract o f s e n na i n a cap acio u s m o r

t ar w i t h carbo nat e o f mag ne si u m i n a m o u n t s u ffi ci e n t t o
,

for m a c ream y m ix t u re ; t he n grad uall y ad d t h e w i n e ,

s t irri n g w ell an d fi l t er
,
La st l y di ssol v e t h e tar tar
.
,

e m e t i c i n t h e fil t rate The origi n al for m u la u sed se nna

.

l ea v e s i nst ead o f th e fl u id ex tra ct o f sen n a

,
.
1 28 EL I XIR F O RM U LE
'

E L I x I R O F L A C T O - P H O S PH A T E O P L I M E . .

( Eu xIR O F LA CT O -P H OS P H TEA OF CA LC U M )
I .

P rec i p i t at ed P h os p h a t e of C al c i u m 1 28 g rai n s
S i m p l e E l i x i r, L act i c A ci d , H y d ro c h l o ri c A c i d , A m m on i a
W at er , D i s t i l l ed W at er , of ea c h a s u ffi c i e n t q u a n t i t y .

Mix th epre c ip i tat ed p h o sph at e o f cal c i u m w i t h s i x

t ee n fl u id o u nce s o f c old di s t illed w at er an d add e n o u g h ,

h y dro chlori c ac id t o di ssol v e i t Fil t e r t h i s s ol u t io n and .

,

m i x w i th i t s b u lk o f cold w at er and t he n ad d am m o ni a ,

w at er u n t i l i n s ligh t ex ce s s Transfer th e mi x t u re t o a .

fi n e m u s li n s t rai n er an d w he n t h e l iq u id h as d rai n ed re
,

t u r n t h e m ag m a t o t h e v e ssel m i x i t w i t h t h e am o u n t o f ,

w at er be fore e m plo yed an d ag ai n t ran sfer i t t o th e

,

s t rai n er . A s s oo n as th e m ag m a i s agai n drai n ed t ran s ,

fer i t t o a m ort ar an d di ss ol v e i t b y t h e addi t io n O f a s u ffi

ci e n t am o u n t o f l act i c ac id Fil t er t hi s and ad d e n o u gh
.
,

s i m ple elixir t o prod u c e s ix t ee n fl u id o u n c e s .

Each fl u id drach m ( t easpoo nfu l ) o f t h e fi n i shed eli x i r

co n tai n s o n e g rai n o f l act o pho spha t e o f cal ci u m -
.

EL I x I R O P L I QU O RI C E .

F l u i d Ext ract of Li q u ori ce 2 flui d ou n c es

S i m p l e El i x i r
C arb on at e Of M ag n e s i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e fl u id ex t ract O f liq u ori ce i n a cap aci o u s

m or tar w i t h carbo nat e o f m ag n e s i u m i n am o u nt s u fli ci e n t
t o for m a c re am y m ix t u re t h e n grad u all y ad d t h e s i m ,

ple elixir st irri ng w ell an d fi l t er

, ,
.

Each fl u id d rach m o f t h e fi n i shed elixi r repr es e nts se v e n

an d a h al f m i n i m s o f fl u id ex t ract o f liq u o ri c e Thi s .

ep ar a t io n i u s ed m ai n l y t o di sg u i s e t h e tas t e o f i
p r s q u
 EL I XIR F O R M U LZE . 1 29

i e Elixir o f gl y cy rrhizi n i s an ad m irable su b st i t u t e

n n . .

The re mark s co ncer n i n g t h at elixir appl y w i t h eq u al per t i

h e nce t o elixi r O f liq u ori c e .

E L I X I R O F L I Q U O R I C E, A R O M A T I C .

F l u i d E x t ract of Li q u ori c e . 1 2 flu i d o u n c es

F l u i d Ex t ra c t of S w ee t O ran g e
F l u i d E x t ra c t of C ori a n d e r
F l u i d Ex t rac t of A n g el i c a S e e d
F l u i d E x t ra c t of C i n n a m on
F l u i d Ex t rac t of C l ov e s
S i m p l e El i x i r

C a rb o n at e of M ag n es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e fl u id ex t rac ts h av i ng pre v io u sl y m ixed

,

t h e m t oge t her i n a cap ac io u s m or tar w i t h carbo nat e o f ,

mag ne s i u m i n a m o u nt s u ffi c ie nt t o for m a c re am y m i x
t u re ; t he n grad u all y ad d t h e s i m pl e e lixir st irri n g w ell , ,

an d fil t er .L as tl y m i x t h e fi l t rat e w i t h t h e al cohol
,
.

Each fl u id drac h m o f t h e fi n i sh e d elixir repr e se n t s se v e n

an d a h al f m i n i m s o f fl u id ex t r ac t o f liq u ori ce t oge t her ,

w i t h aro m at i cs Thi s elixir i s u sed t o di sg u i se t h e tast e

.

o f q u i n i n e w h i c h i t acc o m pli sh e s m ai n l y b y re n deri ng i t

,

i n sol u bl e ; he n ce w e re fe r t h e r ead e r t o o u r re m ark s co n

,

c er n i n g e lixir o f gl y cy rrhi z i n w hi c h m ay w i t h eq u al per

,

t i n en c e be applied t o t hi s prep ar at io n .

A ro m a t i c elixir o f liq u ori c e w as i n t rod u ced t hro u gh

t h e D m gg i sts Ci rcu l ar i n 1 8 79 al t ho u gh s i m il ar prep ara
'

, ,

t io n s h ad b e e n e m plo y ed pre v io u s l y an d t h e eli xir o f ,

liq u ori c e o f M r G G C S i m s ( see D rugg zlrts Ci rcul ar

. . . .
‘
’

1 8 74) w as n e arl y ide n t i cal w i t h t h e abo v e .

1 3 0 ELI XIR F O R M U LE .

E L I X I R E S U C C O L I Q U I R I T I JE .

P R C T O R ALE Eu xIR .
)

P u ri fied L i q u ori c e 2 p art s , b y w ei g h t

F e n n el W at e r 5

Make a s o l u t io n , an d ad d o f

A n i s at ed S p i ri t of A mm on i a’
2 p a rt s , b y w ei gh t

I t for m s lo u d y bro w n liq u id w h i c h m u st be sh ake n

a c , ,

u p be fore di s pe ns i n g I t s ho u ld be pre ser v ed i n w ell

.

c lo s e d e el s
v ss — Ger man P /i ar m acop a i a 1 8 70 ’
, .

Thi s prep ara t io n i s al so called Elixir Pe ct o rale Regi s

D ani tx or Pe ct oral Elixir O f t h e K i ng o f D e n mark
, .

E L I X I R O F C I T RA T E O F L I TH I U M .

C i t rat e of L i th i u m 2 56 g ra i n s
S i m p l e El i x i r 16 flu i d ou n c es

D i ssol v e t h e c i t ra t e of li t hi u m i n th e s i m ple elixir , and

fil t er i f n e ce ssary .

Ea ch fl u id d rach m ( t eas poo n fu l) O f th e fi n i sh ed elixi r

c o n tai n s t w o grai ns o f c i t rat e o f li t h i u m Th i s propor .

t io n w as adop t ed b y t h e J oi n t C o mm i tt e es o f t h e Nat io nal

C o l l ege o f Ph ar ma cy an d th e M edi cal S o cie ty o f t h e D i s
t ri ct o f C ol u m b i a .

°A n i s a ted Sp i r i t of A m mon i a . p
D i ss o l v e o n e ar t of oil O f ani se i n tw e n t y -fo u r
par t s o f al c o h o l , an d ad d fi v e p
ar t s o f am mo n i a w at e r A l l t h e p rO p o rt 1 on s are b y
.

weig h t .
1 32 X
ELI I R F O RM U LAJ ‘
.

e lixir s t irri ng w e ll and fi l ter Las t l y m i x th e fi l t rate

, ,
.
,

w i t h t h e al cohol .

Each fl u id dra ch m of t h e fi ni shed elixi r r epre se nt s

su c h p ar t o f s e v e n and a h al f m i n i m s o f fl u id ex t ract o f

m at i c o as w ill di ssol v e i n t h e m e n st r u u m e m plo y ed i n i t s

prep arat i o n We co ns ider al co hol o f s pe ci fi c g rav i ty
.

t o b e t h e prop er m e n st r u u m fo r exh au st i ng t h e
m edi c i nal pri nc iple s fro m m at i co and th e addi t io n o f ,

w at er de c re as e s i ts sol v e nt po w er i n propo rt io n t o t h e
a mo u nt o f w at er add e d I n co nseq u ence O f t h i s fa ct
.

w e o bj e c t t o an elixir o f m at i co .

CO M PO U ND E L I XI R O F M A T I C O .

F l u i d E x t rac t of M at i co 3 flu i d ou n c es

F l u i d E x t ra c t of B u ch u 1

F l u i d E x t ra c t of C u b eb s
S i m p l e El i x i r
C arb on at e of M ag n es i u m , a s u ffi c i en t q u an t i ty .

M i x t h e fl u id ex t ract s e v ap o rat e t h e m ix t u re at a
, an d ,

°
te m perat u re o f abo u t 1 50 F t o o n e h al f i t s b u lk
.
, Tr i t .

u rat e t h i s w i t h a su ffi c ie nt am o u n t o f carbo nat e o f m ag

n es i u m t o for m a cream y m i x t u re t he n grad u all y st i r i n ,

t h e s i m pl e elixir an d fil t er , The fl u id ex t ract s fo r t he

.

fore goi n g prepara t io n s ho u ld be m ade w i t h al cohol 5 g . .

The propor t io n an d i n gredie nt s o f t h i s elixir and ,

u po n w h i ch w e h av e b ased o u r for m u l a w ere gi v e n ,

i n t h e D mggvkts Ci rcu l ar I SSO

’
.
,

Each fl u id drach m o f t h e fi n i shed el ixir w ill co n

t ai n s u c h an am o u n t o f t h e proper t ie s o f abo u t e le v e n
m i n i m s o f fl u id e x t r act o f m at i c o an d t hree an d o n e h al f -

m i n i m s e ach o f b u c h u an d C u beb s as w ill di ss ol v e i n t h e ,

m e ns t r u u m S i n ce i n o u r opi n io n s t ro ng al co hol o n l y
.
, ,
 ELI X IR F O R M U LIE . 133

w il l pe rfe c tl y ex tract th e m edi c i nal pri nciple s o f t h e se

dr ug s t h e act u al v al u e o f t hi s eli xir i s v ery m u ch le ss
,

t h an t h at o f an eq u i v ale n t am o u n t o f t h e origi nal fl u id ex

t ract s an d i t s u se b y t h e p h y si ci an m u st be u n sati s fac
,

t o ry .

E L I X I R O F M AY -A P P L E .

( EL1 x 1 R OF PO D OP H YLLUM . EL1 x 1 R OF M A ND RAK B .

)

F l u i d E x t rac t o M y ap p l e
f a - 2 flu i d ou n c es

S i m p l e El i x i r
A l coh ol
C a rb o n at e of M ag n es i u m , a s u ffi c i en t q u a n t i t y .

Tri t u rat e th e fl u id ex t ract O f May apple i n a cap acio u s -

m or tar w i t h carbo nat e o f m ag n e s i u m i n am o u n t su ffi c ie n t

,

t o for m a c re am y m ix t u re t he n gr ad u all y ad d t h e s i m
,

ple eli xir st irri ng w ell an d fil ter Last l y m i x t h e fi l

, , .
,

t rat e w i t h t h e al cohol .

Each fl u id drach m o f t h e fi n i shed elixir repre se n ts

s u c h an am o u n t o f s e v e n an d o n e h al f m i n i m s o f fl u id ex -

t ra ct of M ay apple as t h e m e n s t r u u m can di ssol v e

-
.

S i nce res i n o f podoph y ll u m i s al m o st i n sol u ble i n w at er

’

w e d o n o t ad mire t h e abo v e pr ep arat io n .

CO M P O U N D E L I X I R O F M A Y -A P P L E .

( CO M UND
PO EL I x I R OF PO D HYLLUM
OP . CO M UND
PO ELI x I R OF M A ND RA x R .
)
F l u i d E x t ra c t of M ay -ap p l e 1
% fl uid ou n c e s

F l u i d Ex t ra c t of S en n a
O il of A ni se minim s
S i m p l e El i x i r 14 flu i d ou n c es

C a rb o n a t e of M ag n es i u m , a s u ffi c i e n t q u an t i t y .

M i x t h e fl u id ex t ract s ri t u rat e t h i s i n a cap ac io u s

an d t
m o rt ar w i t h carbo n at e o f m ag n es i u m i n am o u nt s u ffi ci e n t
,
 EL l R F O R M U LIE .

t o for m a ream y m i x t u re h av i n g pr ev io u sl y t ri t u rated

c ,

t h e o i l o f a n i s e w i t h t h e m ag ne s i u m carb o nat e ; t h e n
grad u all y ad d t h e s i m ple elixi r s t i rri ng w ell and fil t er , , .

L ast l y m i x th e fi l t rat e w i t h t h e al cohol

, .

E ach fl u id drach m o f t h e fi n i shed elixir repre se n t s

"

su bje c t t o c o n di t io n s n o t ed u n der elixir o f M ay apple

( ) -

abo u t fi v e m i n i m s o f fl u id ex t rac t o f M ay apple an d t h re e -

,

m i n i m s o f fl u id ex t ract o f se nna A for m u l a fo r t h i s prep

.

arat io n w as propo se d b y t h e D rugg zlrts Ci rcul ar 1 8 72

’

, ,

c o n tai n i ng i n s u b stan c e t h e fore go i n g i n gredie n t s The .

r e m ark s w e m ake r e gar d i ng elixir o f M ay apple applie s -

,

t o t hi s co m po u n d al s o al t ho u gh w e h av e t h e ad v an t ag e
,

o f t h e s e n na i n t hi s i n sta nc e w h i c h y ield s i t s m ed i c i nal

,

i n iple s t o t h e m e n s t r u u m co m po s i ng t h e elixir
p r c .

CO M P O U N D E L I X I R O F M YR R H .

( EL1x 1 R M Y R R i r/E C O M PO S r r U M ) .

Ex t rac t of S av i n 1 t roy ou n c e

T i n ct u re of C as t or 1

T i n ct u re of M y rrh
D ige st t he moge t her an d strai n
t Th i s prep arat i o n .

i s i m pro v ed fro m o n e de sc ribed i n so m e for m er di s pe nsa

t orie s u n der t h e nam e o f El i x i r Utm nu m
’
”
.
,

N ew D is p e n s at o r y , Lo n d o n ,

E LI XI R O F N U X V O M I C A .

T i n ct u re of N u x V om i c a 2 56 m i n i ms
S i m p l e El i x i r 1 4 flu i d ou n c es

A l c o h ol
A c et i c A c i d m i nims
P ow d ere d W ood C h arcoa l , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e t i nct u re o f n u x v o m i ca i n a cap ac io u s

m ort ar w i t h po w der e d w ood c h arc o al i n am o u n t s u ffi ci e n t
,
 1 36 EL1X 1 R F O R M U LA;

for m u l a . T hi s w as fo u n d
a m o ng th e e ffe cts o f t h e l at e
D r J R C hil t o n w h o s tate d t h at he ob tai ne d i t fro m
. . .
,

D r J oh n B M c M u nn t h e origi na tor o f t h e elixi r

. .
, Th e .

pro cess may be su m m arized as follo w s

Exh au st g um opi u m w i t h s u cce ss i v e m acerat io ns i n
s u lph u ri c e t her A ft er t h e fi nal d ecan ta t io n o f t h e e t her
.
,

boil t h e opi u m i n w at er u nt i l all o d or o f su l p h u ri c e th er

h as di sappe ared and t he n s t rai n t h e sol u t io n per mi t i t
, ,

t o s e t t le de cant t h e clear l i q u id and ad d rat her m ore

, ,

t h an i t s b u ll : o f al coh ol .

I t w ill be o b ser v e d t h at t h e foregoi ng pro ce ss prod uc e s

s i m pl y a s ol u t i o n o f opi u m fro m w hi c h t h e narc o t i n e an d

and O pi u m odor h av e bee n re m o v ed b y m e an s o f pre v i

o u s m ace rat io n w i t h s u lph u ri c e t her an d t h e O ffi c i nal ,

( 1 8 8 3) deodorized t i n c t u re o f opi u m m ay be c o n s ider e d a

s u b st i t u te .

EL I XI R O F O RA N G E .

O il of O ran g e , fres h an d p u r e ’
30 m inims
S i m p l e S y ru p 8 flu i d ou n c es

A l c oh ol . 4
D i s t i l l ed W at er . 4
C a rb on a t e of M ag n e s i u m t roy ou n c e

Tri t u ra t e t h e O i l o f orange i n a cap ac io u s m or tar w i th , ,

t h e carbo nat e o f m agn e s i u m ; t he n grad uall y add t he si m

l sy r u p s t irri n g w ell h av i n g p r ev io us l y m ixed i t w i t h
p e , ,

t h e w at er an d o n e h al f t h e al c ohol and fil t er i t
-
Last l y , .
,

m i x t h e fi l t rat e w i t h t h e r e m ai n der o f t h e al cohol Thi s .

h as an ex celle n t fl av or an d can be u sed i nst e ad o f s i m pl e,

P u re o i l o f or ang e m u st b e u se d in this p p
re arat i on . M u ch of t h e c o mm e rci al o i l

p r o d u c e s an e l i x i r p i
w h i c h h as t h e o d o r an d t a s t e o f t u r e n t ne , an d so m e t i m e s o n l y o f
tur p en ti n e g p g
W e w i l l s u g es t t h at u r e m l o f o r an e c an o n l y be o b t ai n e d b y ayi n
.

p
p f
.

the r i c e at w h i c h i t c a n b e s o l d , b u t i t d o e s n o t o ll o w t h a t al l o f t h e h 1g h - p r 1c e

oi l is p u re .
 E LI XI R F O R M U LIE . 1 37

el i x i pre ferre d
r if . O ur s i m ple elixi r co ntai ns m ore O i l
t han t h e fo re g oi ng , but i t i s m ore t ro u bl e s o m e t o m ak e .

E L I X I R O F P AN C R E A S .

Take si x p an cre as and ch o p th e m i n t o p i e ce s, and

m acerat e t h ree day s i n a m i x t u re of

W at er .

G l y c eri n e
H y d ro c h l ori c A ci d 4 flu i d ou n ces

The r i n st a n an d ad d
t w o an d o n e h al f fl u id d rachm s o f -

oil o f orange gl y ceri n e i n a m o u nt su ffi c i e n t t o p rod uce

,

t w e n t y pi n t s and t he n fil t er
, .

Thi s for m u la w as anno u nce d i n 1 8 73 t hro u gh t h e ,

A meri can j ournal of P harmacy by D r R V M a tt i so n , . . .

,

w h o s tat e s t h at o n e fl u i d drach m o f th e e l ix i r w i ll e m u l
s i fy o ne hal f o f a fl u i d o u n ce o f cod l i v e r o i l
-
.

E L I X I R O F P A R EI R A B R A V A .

F l u i d E x t ract of P arei ra B rav a 2 flui d ou n c es

S i m p l e El ix i r
C arb on at e of M ag n e s i u m , a s u fli ci e n t q u an t i ty

Tri t u rat e t h e fl u i d ex t ract o f p arei ra brav a i n a cap a ,

c i o u s m or tar w i t h carbo nat e O f m ag n e si u m in am o u n t

,

s u ffi c i e n t t o for m a c re am y m ix t u r e t he n grad u all y ad d

t h e s i m ple eli xi r s t i rri ng w ell an d fil t er
, , .

Each fl u id drach m o f th e fi ni shed elixir repr e se n t s se v e n

an d a h al f m i n i m s o f fl u id ex t rac t o f p areira brav a .
 1 38 ELI XIR F O R M U LzE .

ELIXI R O F P A R E I R A B R AV A A N D B U CHU .

El i x i r of B uch u 8 flui d ou n c es

El i xi r of P a r ei r a B rav a 8

M i x t he m t oge t her .

Each fl u id drach m ( t e aspoo nfu l ) o f t h e fi ni sh ed e l ix i r

c o n tai n s s u c h an am o u n t o f fo u r m i n i m s eac h o f fl u id e x

t rac t o f b u c h u an d fl u id e x t ra ct of p areira bra v a as w i l l

d i sso l v e i n th e menst r u u m .

E L I X I R P AR EGO R I C U M .

( C A M P H O R A T RD T I NC T UR E OF O PI UM )
Th e for m u l a o f th e L o n do n Ph ar m acop oei a , 1 770 , w as
t ake n fro m L e M or t ex c ep t i ng h o n ey liq u ori ce and p o
, ,

t assi u m carbo nat e I t i s stat ed i n th e

. N e w D i spe n sa
t ory p u bli shed i n L o ndo n 1 770 t h at t hi s prep arati o n
”

, , ,

w as origi nall y k no w n as El i xir A s th m ati c u m .

P EC T O R A L EL I XI R O F T H E E D I N B U R G H P H A R M A C O
P CE I A , 1 770 .

2 t roy o u n ces

11

A l co h ol 32 flu i d ou n c es

D ige st i n a san d bath for t hree d ay s , t he n fil t er ( I t .

sho u ld be made by macerat io n i n st e ad o f

,
—
h eat L) .

The pe ct oral e lixi r O f m od e r n t i m e s i s Elixir e S u cco

t o w hi ch t h e re ader i s re ferred
”
Li q u i ri tee , .
1 40 ELI X IR F O R M U LIE .

“
probabl y ab se nt fro m Elixir o f Pep s i n an d B i sm u t h ,

an d he n c e t h at t h e v al u e o f t h i s elixi r depe n d s u po n t h e

al c oho l o n l y We h av e b e e n s o m ew h at s u ccessfu l i n
.

o v er co m i ng th e i n co ngr u i t i es w e h av e j u st nam e d b y s u b
st i t u t i ng ace t i c ac id fo r h y dro c hlori c ac id i n t h e pr e p ara

t io n o f t h e pep s i n liq u id t h u s p e r m i tt i n g i t t o b e
,

m ixed w i t h t h e bi sm u t h sol u t io n w i tho u t pr e c ip i tat io n

o f bi sm u t h an d al s o t h e app are n t s ol u t io n o f p e p s i n i n
,

t h e pre se n ce o f am m o n io c i t rat e o f bi s m u t h-
We u se .

“
t h e t er m app are n t s ol u t io n o f pep s i n fo r al t ho u gh
”

t h e pep s i n u n do u b t edl y di sappe ar s i t d oe s n o t n ecessa ,

ril y follo w t h at i t di ss ol v e s and re mai ns act i v e pep si n .

Perh ap s i t i s so m od i fied as t o b e de v oid of dige st i v e

v al u e an d s t i ll re m a i n di ssol v ed
, U po n t h e o t her ha n d
.
,

e v e n i f t hi s i s t h e cas e i t i s b arel y po ssible t h at suc h a

,

pep si n i s o n l y p aral y zed an d t h at i ts v i t ali ty w ill re t u rn

,

w he n i t i s take n i nt o t h e st o m ach Th i s s u bje ct i s p ecu

.

l i arl y p ai n fu l t o t h e c o n sc ie n t io u s ph ar m aci st an d w e re ,

i t n o t t r u e t h at t he se c o m bi nat io ns are de man ded by

ph y s i ci an s w e m igh t e v e n ignor e t he m al t oge t her A s
, .

i t i s o u r re m ark s m ay be o f v al u e and t h e re s u l t o f
, ,

o u r ex p eri me n t s m ay be i n t er est i n g t o o t her s .

p p
I t i s b y n o me an s c e r t ai n t h at s u c h a sol u t i o n of e s i n i s i nj u r ed reg ar d i n g i t s
g p
d i e st i v e o w e r b t h e s u b s t i t u t i o n o f ac e t i c ac i d for h y d r o c h l o r i c ac i d T rue i t is
fi
.

t h at t o d i s s o l v e al u m o n ar t i c i al l y h y d r o c h l o r i c ac i d i s n e c e s sar y , b u t t h e j u i c e s i n
t h e s t o mac h may r e n d er i t u nn ece ssar y . See El i x i r of P e si n p .
 E LI XI R F O R M UL/E . 4 1

EL I X I R O F P E P S I N .

P ep s i n , S ac ch a rat e d " 2 56 i
g r a n s

S i mpl e El ixi r 1 6 flu i d ou n c es

A c et i c A ci d 2 flu i d d ra c h m s

Mix t he m t oge t h er and

h ake o ccas io nall y d u ri n g a
s

period o f no t le ss t h an t w e n ty fo u r ho u rs D o no t fi l te r -
.

u n le ss ab sol u t el y n e c e ssar y Th e ac id u s u all y e m plo y ed

. .

t o e ffe ct t h e s ol u t io n o f pep s i n ( h y dro ch lori c a c id) i s s u b

st i t u t ed i n t hi s cas e by a ce t i c ac id We do t hi s i n orde r .

t o O b t ai n a s i m ple elixir of pep s i n m ore c o m p at ibl e w i t h

cert ai n i ro n sal t s an d w i t h am m o n io c i t rat e o f bi s mu t h -
.

H y dro ch l ori c ac id m ay be n e ce ssary i n c o n n e ct io n w i t h

ep i n t e ffe t t h e ar t ifi c i al s ol u t i o n o f c o ag u l at ed alb u
p s o c

m en b u t w e are b y n o m e an s co nv i nc ed t ha t i t i s a
,

n e cess i ty w he n t h e pep s i n i s i n t h e s t o m ach I n deed t h e .

,

prob abi li t ie s are t h at th e gast ri c j u i ce s u pplie s th e ac id

pri nciple e v e n i n v ery d y spe p t i c perso n s and repor ts
, ,

fro m t ho s e w h o u se d ry pep s i n co rrobo rat e t h e i nfere n ce .

Each fl u id drac h m ( t ea s poo n fu l ) o f t h e fi n i shed e lixi r

c o n tai n s t w o grai n s o f sacc h arat ed pep si n .

The for m u l a fir s t b ro u gh t t o o u r n o t i ce fo r elixir o f

ep i ppe red h D C Fr ’

p s n a a i n t e ru gg vlrts i rcu l ar 1 8 6 9 es h , .

r e n n e t w as e m plo y e d w i t h sal t w i n e an d aro mat i cs

, , .

Th e for m u l a w e pr es e n t c o ntai n s th e propor t i o n o f p e p si n

r e co mm e n ded b y t h e A m eri can Ph ar m ac e u t i cal A s so c i a

t i o n 1 8 73
, .

l"
Sac c h ar at e d pp
e si n is o fli ci n al h ence ou r d i rect i on t o us e t h i s form At .

r esen t p si n nearl y p
u r e i n s c a l es may b e r e ad i l y o b tai n ed , an d t h er e can c er t ai nl y
p
e
p
e n o o bj e c t i o n t o t h e u s e o f a n e q u i v al e n t p
rop o r t i on .
1 42 ELI X IR F O R M U LE .

E L I XI R OF P EP S I N W I TH C I TRA TE O F AM M O N IU M
AND B ISM U TH , AN D P H O S P HATE OF QU I N I N E .

( Eu x tR o r P E PS I N , B M UTH
IS A ND QU N 1 1A. )

El i x i r Of P ep si n an d A m m o n i a- C i t r at e of B i sm u th . 8 flu i d o u n ce s

El i x i r of P h o s p h at e of Qu i n i n e . 8

Mix t h e m t oge t he r ,e z an d
refu l l y b y n u t rali e v ery ca

me an s o f ace t i c ac id or amm o n i a w at er .

Each fl u id drach m ( t easpoo n fu l ) o f th e fi n i shed elixi r

c o n tai n s o ne h al f gr ai n e ach o f sacc harat ed pep s i n am
-
,

mo nio ci t rate o f bi sm u t h an d pho sph ate o f q u i n i ne

-
.

Thi s elixir s ho u ld be d i scarded as i t i s u n cer tai n u nsta , ,

ble and made o f i nco m p at ible s .

E L I XI R O F P E P S I N A N D P H O S P HA TE OF CINCH O N I
D IN E .

( EL1x 1 R or P E PS I N AND C I NC HO Nl D l A. )

El i x i r of P ep s i n 8 flu i d ou n c e s

El i x i r of P h os p h at e of C i n ch o n i d i n e. 8

M i x t he m t oge t her . I f no t of ac id reac t io n add a su f

fi ci e n t o u nt o f ace t i c ac id
am .

Each fl u id drach m ( t easp o o nfu l) o f th e fi ni shed eli xir co n

tai n s o n e grai n o f sa cch arat ed p ep si n an d o ne h al f gr ai n -

o f pho s p h at e o f ci nc ho n idi n e .

EL I XI R O F P E P S I N W I TH P H O S P HATE O F C IN C H O N I
D IN E AND S T R YC H N I N E .

( ELI x I R OF P E N
PS I , CI NC H N D O I IA AND ST R Y C H N l A ) .

El i xi r of P ep s m an d P h os p h at e or C i n c h on i d i n e . 8 flu i d ou n c es

S t ry c h n i n e
A c et i c A c i d , a s u ffi c i en t q u an t i t y .

Tri t u rat e t h e s t ry ch n i n e i n a m or t ar w i t h ,
ac etic ac id
i n su ffi cie n t am o u n t t o e ffe ct i ts s ol u t io n , an d t he n ad d
1 44 ELI XIR F O R M U LE .

ELI XI R O F P E P S I N A N D W A F ER A S H .

( Bu xI R o r P ra
'
A AND P a rs m .
)

F l u i d E x t rac t of P t el e a 2 flu i d o u n c es

El i x i r of P ep s i n 16

P ow d er ed W o od C h arcoal , a s u ffi c i en t q u a n t i t y .

fl u id ex t ract o f p t e l e a w i th po w d ered w oo d
T ri t u rat e t h e
ch ar co al i n am o u n t s u fl i ci e n t t o for m a t hi ck p ast y m i x
‘
,

t u re ; t he n grad u all y ad d t h e e lixir o f pep si n an d fil t er , .

E ach fl u id d rach m o f t h i s pre p arat io n repre s e n ts su ch

an am o u n t o f se v e n an d a h al f grai n s o f t h e m edi c i nal

pri n ciple s o f p t elea as w ill di ss ol v e i n t h e e lixir o f pep

si n , and t w o g rai ns o f sacc h arat ed pep s i n H o w e v er .
,

as t h e proper m e n st r u u m fo r ex t ract i ng t he s e pri n c iple s

fro m p t ele a t ri foli ata i s al cohol 5 g t h e elixir i s

. .

n o t a repre s e n tat i v e o f t h e fl u id e x t ract o f p t e le a u s ed i n

m aki ng i t We d ire ct p o w dered w ood ch ar co al i ns tead o f

.
,

t h e m agn e si u m carbo nat e or m ag n e s i u m pho sph at e as ,

t h e firs t w o u ld n e u t ralize t h e ac id o f t h e elixi r o f pep s i n ,

w h ile t h e l ast w o u l d d i ssol v e t o a c o n s iderable ex t e n t .

EL I XI R O P P EP S I N A N D P H O S P H AT E OF QU I N I N E .

( ELI x I R or P E Ps1 N AN D Q U 1 N 1A . )
El i x i r of P ep s i n 8 flui d ou n c es

El i xi r of P h os p h at e of Qu i n i n e 8

M i x t he m t oge t her .
,

E ac h fl u id drach m ( t eas poo n fu l ) of th e fi n i shed elixi r

o
c n tai n s o n e gr ai n o i s a c chara t ed pep s i n an d o n e h al f -

grai n o f q u i ni ne .
 EL I XI R F O R M U LIE .

E L I X IR O F P EP S I N , P H O S P H A T E O F QU I N I N E AN D
S T R YC H N I N E .

Emm a 0 1" P E N QU N
PS I , I I A A ND S T RY C H N IA .
)

El i x i r of P ep s i n 8 flu i d ou n c es

El i x i r of P h os p h at e of Qu i n i n e 8
S t ry c h n i n e g r a i n s

A cet i c A c i d , a s u fli ci e n t q u a n t i t y.

Tri t u rat e t h e st r y ch n i n e i n a m or tar w i t h ace t i c acid ,

i n am o u n t s u ffi c ie n t t o e ffe ct i t s s ol u t io n ; t he n ad d t h e
elixir s h av i ng prev io u sl y m 1x e d t he m t oge t h e r
,
.

Each fl u id drach m ( t e aspoo n fu l ) o f t h e fi n i shed elixir

c o n tai n s o n e grai n o f sacch ar at ed pep s i n o n e h al f grai n ,

o f q u i n i n e an d o n e fi ft i e t h o f a gr ai n o f s t ry c h n i n e
,
-
.

E L I X I R O F P E P S I N , P H O S P H AT E O F QU I N I N E , S TRYC H
N IN E AN D C I TRAT E O F AM M O N I U M
AN D BISM U TH .

( EL1 x 1 R E N QU N
OF P PS I ,
I 1A , S T RYCHN IA AN D B M UTH )
IS .

E l i x i r of P h os p h at e of Q u i n i n e 8 flu i d ou n c es

E l i x i r O f P ep s i n an d A m m on i o- C i t r at e of B i sm u t h . 8
S t ry c h n i n e
A c et i c A c i d , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e st ry ch n i n e i n a m or tar w i th ace t i c acid ,

i n am o u n t su ffi cie n t t o e ffe ct i t s sol u t io n an d t he n ad d ,

t h e eli x ir s h av i n g pre v io u sl y m ixed t he m t oge t her

, If .

t h e e lixir h as an ac id or an alk ali n e r e act io n cau t io u s l y ,

ad d e n o u gh amm on i a w at er or ace t i c ac id as th e case ,

m ay de m and t o re n der i t n e u t r al
, .

Eac h fl u id drach m ( t e as poo n fu l ) o f t h e fi ni shed elixir

co n t ai n s o n e h al f gr ai n eac h o f sacch ar at ed p e p s i n q u i
-
,

n i n e an d am m o n io c i t r at e o f bi s m u t h an d abo u t o n e fi f
-
,
-

t i e t h grai n o f s t ry ch n i n e Thi s i s an asso ci at io n o f i n

.

co ngr u i t ie s an d s ho u ld be di sc arded
, .

13
 4 6 EL l R F O R M U LA‘I .

EL IX I R O F P EP TO N E .

t roy ou n c e s

z n
1 flu i d ou n c e s

O O O O O Q O O O O O O C O O O O OG O O O O O O O O O O O O O O O O O O O O O

D i ssol v e th e p e p t o n e i n t h e w at e r t h en ad d t h e w i n e ,

an d su gar ,
an d aft e r t h e su g ar h as di s s ol v ed add t h e al

c ohol .

A P ET T I I
.
‘ ‘
.

EL I X I R O F P H O S P H O R U S .

P h o s p h oru s g r ai ns

Et h er 3 fl u i d d ra c h m s
A l c oh ol 1
% fl u i d ou n c e s

E s s en c e of P e p p e rm i n t fl u i d d r ac h m
G l y c eri n e fl u i d ou n c es
S i m p l e El i x i r

Weigh t h e pho sphor u s care fu ll y i n a gl ass st oppere d -

v i al , an d t he n ad d t h e e t her ; agi t at e u n t il t h e ph o s

h o ru s di ss ol v e s t he n a dd t h e al c ohol an d t h e e s s e n ce
p ,

o f pepper m i n t ; n o w s lo w l y ad d t h e gl y c eri ne s t irr i n g ,

w ell an d l ast l y th e s i m pl e e lixir

,
.

E ach fl u id drach m ( t eas poo n fu l ) o f t h e fi n i sh e d e lixi r

c o n t ai n s t h e o n e h u n dr e d t h o f a gr ai n o f pho sphor u s
-
.

Elixir o f pho sphor u s i s li abl e t o be co m e m ilk y o w i n g t o ,

t h e fact t h at pho s phor u s i s i n s ol u bl e i n w at er Thi s .

for m u l a i s ess e n t i all y t h at o f M r J G L u h n as p u b . . .

,

li sh ed i n t h e A meri can j ou rnal of P l zarmacy 1 8 74 , .

148 EL1x 1R F O R M U LA‘J .

EL I X I R O F A R S E N I T E O F P O TA S S I U M .

of A rs e n i t e of P ot as s i u m ( F o w l er So l u ti o n ) mi ni m s
’
S ol u t i on s . . 2 56

S i m p l e E l i x i r, a s u ffi c i e n t q u a n t i t y .

M i x th e s ol u t io n r e i te o f po tass i u m w i t h e n o u gh
of a s n

s i m ple elixir t o prod u c e s ix t e e n fl u id o u n ce s .

E ach fl u id drach m ( t ea spoo n fu l ) o f t h e fi n i she d elixir

c o n tai n s t w o m i n i m s o f s ol u t io n o f ar s e n i t e o f po tass i u m .

D o se o n e fl u id drach m ( t e aspoo nfu l ) w h i c h m ay be cau

, ,

t i o usl y i n c reas ed t o t w i c e t h at am o u n t .

E L I X I R O F AC E TA T E O F P O T A S S I U M A N D BUC HU .

A c et at e of P ot as s i u m 6 4 0 g rai n s
E l i xi r of B u ch u , a s u ffi c i en t a m ou n t .

D i sso l v e th e ace tat e o f po tass i u m i n e n o u gh elixir of

b u ch u t o prod u ce s ix tee n fl u id o u n ce s .

Each fl u id drach m r e pre se n t s fi v e grai n s o f ace tate of

po tassi u m .

EL I XI R O F B U C H U , J U N I P ER , AN D ACE TA T E O F PO
T AS S I U M .

T hi s prep arat io n i s m ade b y p ar t ie s w h o h av e ad v er

t i se d an d c re at ed a d e m an d fo r i t i n cer tai n s e c t io n s o f
o u r co u n t r y an d t o w ho m t h e for m u l a righ t fu ll y b e
,

lo ng s Thro u gh co u r te sy to t he se ge nt le m e n w e do n o t
.

gi v e a pro ce ss fo r maki n g i t .

EL I XI R O F B R O M I D E O F P O T A S S I U M .

B rom i d e of P ot as s i u m 1 280 g ra i n s

S i m p l e El i x i r, a s u ffi c i e n t q u an t i ty .

D i ssol v e th e bro m ide o f po tass i u m i n tw el v e fl uid

o unces of s i m pl e elix i r and ad d t o t h i s
, l
so ut i o n en o ugh
 ELI XIR F O RM U LE .
49

s i m ple elix i r t o br i ng t h e w hole to th e m easu re o f si x

t ee n fl u id o u n c e s .

Each t e aspoo nfu l o f th e fi n i shed e lixir repre sen t s ten

grai ns O f po tassi u m bro m ide and i s t h e sam e i n st re ngt h
,

as t h at adop t ed b y t h e A m eri can Ph ar m a c e u t i cal A ss o c i

a t io n 1 8 75
,
.

E L I XI R O F I O D I D E O F P O TA S S I U M .

I od i d e of P ot a s s i u m 2 56 g rai n s

S i m p l e E l i x i r, a s u ffi c i e n t q u an t i t y .

D i ssol v e iodide o f po ta ss i u m
th e in e n o u gh si m p l e
elixir t o prod u ce s i x t ee n fl u id o u nce s , and fil t e r i f neces

s ar y .

E ac h fl u id drach m ( t e aspoo nfu l ) o f t h e fi n i she d e l i x i r

c o n tai n s t w o g ra i n s O f i odide o f po ta ss i u m .

E L I X I R P R O P R I ET A T I S .

( P A Rc s Ls us E
'
LX R)
I I .

M y rrh 3 t roy ou n ces

A l c oh ol 2

Red uc e t h e dr u g s t o a co ar se po w der and m acera t e i n ,

t h e al cohol fo u r t e e n d ay s st irri n g th e m i x t u re t ho r
,

o u gh l y e ac h d ay ; t he n fil t er S e e al so page
( .

(S u pp l eme n t to Lo n d o n P h ar maOO p mi a,

E L I X I R P R O P R I E TA T I S C U M A C I D O .

Add t o e lixir proprie tat i s o f aro m at i c s u l p h u ri c , ac id

an a m o u n t s u ffi cie n t t o re n der i t fairl y aci d Th e . su p
1 50 ELI XI R P O R M U LAE .

p le m e n t t o t h e L o n do n Ph ar m acop oei a 1 8 2 1 d ire ct s , ,

w h at i n t he se d ay s w o u ld be c o n sidered an u n re aso nable

am o u n t o f ac id
( S ee . al so our for m ul a o n page 1 3 ,

wh i ch i s B oerh aav e s ori gi n al for m u l a fo r m aki n g Elixi r

’

Proprie tat i s w i t h D i st illed

R A D C L I F F S P U R G I N G EL I X I R
’
.

t roy ou n c e s

C ap e A l o e s
G en t i a n :
C a n el l a A l b a
O ran g e P ee l , B i tt er
G ra i n s of P arad i se
S c am m on y
S en n a .

D i l u t ed A l coh ol

Red u ce t h e dr u g s t o a co ar se po w der m i x t he m w i th ,

th e dil u t ed al cohol and m ac era t e fo u r t ee n d ay s st irri ng ,

the m ix t u re t h oro u ghl y e ac h d ay ; t he n fi l t er .

(S u p p l eme n t to Lo n d o n P h ar mac o p oeia, 1 82 1 )

CO M P O U N D E L I X I R O F R A S P B E RR Y .

F l u i d Ex t ract of R h at an y I flui d ou n c e s

F l u i d E x t ra c t of C i n n am on
F l u i d Ex t ra c t of C l ov e s
F l u i d E x t ra c t of A l sp i c e
'

F l u i d E x t r ac t of N u t m eg
R as p b e rry Ju i ce
S i m p l e El i x i r
C arb o n at e of M a g n es i u m , a s u ffi c i e n t q u an t i ty .

M i x t h e fl u id ex t ract s an d t ri t u ra t e t h e m ix t u re i n a
cap acio u s m or tar w i t h carbo nat e o f mag n e s i u m i n a m o u n t
,

s u ffi cie n t t o for m a c re am y m ix t u re ; t he n grad u all y ad d

 1 52 ELI XIR F O R M U LIE .

E L I XI R O F R H A M N U S P U R S H I A N A .

( EL1 x 1 R OP C AS C R
A A SAG R D
A A .
)

F l u i d E x t ra c t of R h a m n u s P u rs h i an a 2 flu id ou n c es

S i m p l e El i x i r

C arb on at e of M ag n es i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e fl u id ex t rac t o f rh am n u s p u r sh i ana i n a

cap ac io u s m or tar w i th carbo nat e
, of m ag n e s i u m i n
am o u n t s u fli c i e n t t o for m a c re am y m i x t u re ; t h e n grad u

all y ad d t h e si m ple elixir s t irr i n g w ell an d fil t er

, , .

Last l y , m i x t h e fil t rat e w i t h t h e al c ohol .

Each fl u id drach m O f t h e fi n i shed e li xir repre se nts

s e v e n an d a h al f m i n i m s o f fl u id ex t rac t o f rha m n u s u r
p
sh i ana .

CO M P O U N D EL I XI R O F R H A M N U S P U R S H I A N A .

F l u i d E x t ra c t of R h a m n u s P u rs h i a n a 2 flu i d ou n c es

F l u i d E x t r ac t of B el l a d o n n a m inims
T i n c t u re of C a r d a m om
C i t rat e of S t ry c h n i n e 1 g r ai n

A m m o n i a c al G l y cy rrh i z i n 30 g rai n s
S i m pl e El ix i r 16 flui d o u n c es

A l coh ol
C arb on at e of M ag n e s i u m , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e m i xed fl u id ex t racts i n a cap ac io u s mor

t ar w i t h am m o n i acal gl y cy rrhi z i n an d carbo nat e o f m ag
,

n esi u m i n am o u n t su ffi c ie n t t o for m a c re am y m ix t u r e ;

t he n grad u all y ad d t h e s i m ple elixir s t i rri ng w e ll an d , ,

fil t e r Last l y m i x t h e fi l t r at e w i t h t h e al c ohol an d d i s
.
, ,

sol v e i h t hi s t h e c i t rat e o f st r y c h n i n e an d add t h e t i n c ,

t u re o f card am o m .

E ac h fl u id drach m o f t h e fi n i sh e d e lixir repre se nts

abo u t se v e n an d o n e h al f m i n i m s o f fl u id ex t r ac t o f r h am
-

n u s p u r shi an a an d o n e h al f m i n i m o f fl u id ex t ract o f bel

-
 E LI XIR F O R M ou s .
53

l ado nn a and o n e h u n dred an d t w e n ty e igh t h o f a grai n

,
-

o f c i t ra t e o f s t r y c h n i n e .

Thi s m ix t u re w as ann o u n ced by M r H L C oi t b u t . . .

,

w e do n o t k n o w t h at i t w as o f h i s c o n c o ct io n I t ce r .

t ai n l y i s o n e o f t h e m o st O bj e c t io n able o f co m bi n at i o n s ,

an d as u n re as o n able as t ho u gh h an ded do w n fro m t h e

fi ft ee nt h c e n t u r y S u ch m ix t u re s fu r n i s h st ro ng poi n t s
.

for t ho se w h o oppo se elixi r s " .

E L I x I R R OB O R A N S W HYTT II .

Y e l l ow C i n c h on a B a r k 3 t roy o u n c es

G en t i an 1

B i t t e r O ra n g e P e e l 1

A l c o h ol . 1 6 flu i d ou n c e s

C i n n am on W a t er 8

R ed u c e t h e dr u g s t o a co ar se po wder an d prep are a ‘

t i n ct u re b y per c ol at io n u s i n g a m ix t u re o f t h e al co hol
,

an d c i nn am o n w at er Thi s prep arat io n i s a m od e r n t i n c

.

t u re al t ho u gh i t w as o n c e c l ass ed w i t h elixir s
, The .

Ger m an Ph ar m ac op oei a ( 1 8 72 ) re cog n ize s u n der t h e ,

abo v e n am e t h e c o m po u n d t i n ct u re o f c i n c ho na
, .

EL I XI R O F R H U B AR B .

F l u i d E x t ra c t of R h u b a rb 2 fluid ou n c es

S i m p l e El i x i r
C a rb on at e of M ag n e s i u m , a s u ffi c i e n t q u an t i t y .

Tri t u rat e t h e fl u id ex t ract o f rh u b arb i n a cap ac io u s

m or tar w i t h carbo nat e o f m ag n e s i u m i n am o u n t s u ffi c ie n t
,

In our i n t rod u c t i on ( pg w il l b
a e e fo i m d t h e s t a t e m e n t t h at w e h av e n o t d ev i
at e d f
ro m t h e p ro p or n o n f fif o th one- ti e Of a g i
ra n i
o f s t r y c h n n e to e ac h fl i
u d d r ach m
of t h e fi m s h ed el 1 x 1 r.
'
l h
‘

p p ti1s re ara o n 1 s an e x c e p t I O n .
 54 ELI XIR F o R M U Lac .

to f or m a c re am y m ix t u re ; t h e n grad u all y ad d t h e s i m ple

e lixir s t irri n g w ell
,
an d fi l t er
, .

Each fl u id drac h m o f t h e fi n i sh e d elixir repre se n t s

sev e n an d a h al f m i n i m s o f fl u id ex t ract o f rh u b arb .

EL I XI R R H U B A R B , C O M P O U N D .

20 t roy ou n c es

10 flu i d ou n c e s

2 00

D i l u t e d A l c oh ol

M i x th e dr u g s red u ce t he m to a c o ar se po w der
an d ,

an d m acerat e t h i s i n t h e m ixed al c ohol an d w i n e fo r fo u r

t ee n d ay s st irri ng t h e m ix t u re t horo u ghl y e ach d ay

,

t he n fi l t er an d ad d t h e e t her
,
.

Thi s elixir i s re co m m e n ded as a v ehi c le fo r d i sg u i s i n g

t h e t ast e o f cas t or O i l an d w as i n t rod u ced b y M r B ido n e
, .

C arlo w h o s tat e s t h at o n e p ar t o f thi s e lixi r w i ll re m o v e

,

t h e tas t e an d odor fro m t hree p ar t s o f cas t or O i l

. I t w as .

n am ed Elixir o f Rh u barb b u t t o av oid c o nfu s io n w i t h

,

t h e r eg u l ar an d s i m ple elixir o f rh u b arb w e h av e added

t h e w ord comp ou nd .

(S ee N e w R e m e d i es ,

E L IXI R O F R H U B A R B A N D CO LU M B O .

El i x i r of R h u b a rb 5 flui d o u n c es

El i x i r of C ol u m b o 5
S i m p l e El i x i r

Mix h e m t og et h e r
t .

Each fl u id drach m of th e fi n i s hed e li xi r repre se n t s

1 56 ELI XIR F O R M U LZE .

S AC R ED EL I X I R .

( EL1 x 1 R S A CR U M . TI NC T UR E R H EI E T A L ES
O . Ed P h ar m
. .
,

5 d ra c h m s

1 6 fl ui d o u n c es

M i x t h e dr u g s and
r e d u ce t he m t o a co ar se po w d e r ,

an d m a cer at e t hi s i n t h e br an d y fo r fo u r t ee n d ay s s t ir ,

ri n g th e m ix tu re t horo u ghl y e ach d ay t he n fil t er .

( Ed i n b u rg h P h arm O O O p mi a,

EL I X I R O F S A L I C YL I C A C I D .

S a l i cy l i c A c i d 1 28 g ra i n s

P ow d e re d B orax 1 28

S i m p l e El i x i r 1 6 flu i d o u n c es

Tri t u rat e t h e sali cy li c acid and po w dered bor ax t o

g e th e r ad d t h e s i m ple elixir and w he n t h e po w ders are
, ,

di ssol v e d fil t er th e liq u id .

Eac h fl u id drach m ( t e as poo n fu l ) of th e fi n i shed elixi r

c o n tai n s o n e grai n o f sali cy li c ac id .

I n M ar ch 1 88 1
,
D r Wol ff pre se n t ed a for m u l a fo r
,
.

m aki n g t h i s elixir t o t h e Ph il adelph i a C oll ege o f Ph ar

,

m acy u s i ng sali cy li c ac id al c ohol an d si m ple e lixir

, , In .

o u r h an d s i t failed t h e sali cy li c acid c ry s tallizi n g as s oo n

,

as t h e s i m ple elixir w as add e d t o t h e al c oholi c s ol u t io n .

We h av e m et w i t h li tt le su cces s w he n w e h av e en d eav
or e d t o m ake an elixir o f t hi s ac id w i t ho u t u s i n g s o m e
s u b s t an c e s u c h as borax t o ac t as a s ol v e n t O f co u rse .

bi carbo nat e o f s odi u m i s n o t ad m i ssible or o t her alk a ,

li n e carbo n at e o r an alk ali fo r s u ch w ill for m sal t s o f sal

, ,

i cy l i c ac id .
 E LI X IR 1 57

EL I X I R O F S C A M M O N Y .

S c am m on y 2 d rac h m s
D i l u t e d A l c oh ol 8 flu i d ou n c es

H e at an d se t fire to t h e s pi ri t , an d ad d

S u g ar 4 t roy o u n c e s

Whe n i t h as di ssol v ed ex t i ng u i sh
, the fl am e an d ad d

S y ru p of V i ol e t s 2 flu i d ou n c e s

—G U I BO U R 1
‘
.

EL IX I R S A L U T I S .

( EL1x 1 R OF H E LT H
A . CO M UND
PO T 1 N C T U RR OF S E NN A .
)
S en n a 2 t roy ou n c e s

J al ap 1

C ori a n d er
D i l u t ed A l coh ol 3

Red u ce t h e dr u g s t o a coar se po w der and m acerat e ,

t hi s i n t h e dil u t ed al c ohol fo r fo u rt ee n d ay s st irri ng t h e ,

m ix t u re t horo u ghl y e ach d ay ; t he n fi l ter .

( Ed i n b u rg h N e w D i s p e n sat or y ,

EL IXI R O F S EN N A .

F u i d Ex t ra ct of S en n a . 2 flu i d O u n ces

S i m p l e El ix i r
A l c oh ol .

C a rb o n at e of M ag n es i u m , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e fl u id ex t ract o f se nna i n a cap acio u s m o r

t ar w i t h carbo n at e O f m ag n e s i u m i n am o u n t s u ffi c ie n t t o
,

for m a cre am y m ix t u re ; t he n grad u all y ad d t h e s i m ple

elixi r st irri ng w ell an d fil t er Last l y m i x t h e fil t rat e
, , .
,

w i t h t h e al c ohol .

E ach fl u id drach m o f t h e fi n i shed elixir c o n tai ns t h e

m edi c i nal pri n ciple s o f se v e n an d a h al f m i n i m s o f fl u id
ex t rac t O f se n na .
1 58 ELI X IR F O R M U L/E .

ELI X I R S EN N A C O M P O U N D .

F l u i d E x t r ac t S e n n a 4 flu i d o u n c es

F l u i d E x t ra c t T a ra x a c u m
C om p o u n d T i n ct u re C ard am om
S i m p l e El i x i r
C a rb on a t e of M ag n e s i u m , a s u ffi c i e n t q u a n t i ty .

M i x t h e fl u id ex t racts and t i n ct u re an d t ri t u rat e w i t h

ca rbo nat e o f mag n e si u m u nt il o f a cre amy co n s i ste nce ;
t he n grad u all y ad d t h e s i m ple elixir and fil t er .

Each fl u id drach m co ntai n s s e v e n and a h al f m i n i m s o f

fl u i d ex t ract o f Se nna an d abo u t fo u r m i n i ms O f fl u id ex
,

t ra ct O f taraxa c u m .

( S ee A m er i ca n P r a c t i t i on er ,

S I M P L E ELIXI R .

( W H I TE ELI x I R ) .

O il of S w e et O ran g e 1 flu id d rac h m
Oil of L em on
D i s t i l l ed W at er 41 flu i d ou n c es

A l c o h ol 13

S u g ar 32 t r oy ou n ces

C a rb on at e of M ag n es i u m , on e tw o ou n c e b l oc k .

D i ssol v e t h e gar w i t ho u t hea t i n t h e di st illed w at er

su , , ,

an d t he n m i x w i t h t hi s s ol u t io n n i n e fl u id o u n ce s o f al co

hol D i ssol v e t h e O il s i n t hree fl u id o u n ce s o f al c ohol

.
,

an d s lo w l y ad d t h e l iq u id st irri n g c o n s ta n t l y t o t h e so
, ,

l u t i o n o f s u gar Th e n cr u sh t h e blo ck o f carbo n ate o f

.

m ag n e s i u m be tw ee n t h e h an d s per m i tti n g th e po w der ,

t o grad u all y scatt er i t s e l f o v er t h e s u rfac e O f t h e l iq u id

an d s e t t le t o t h e bo t t o m o f t h e v e s sel A ft er st an di ng .

h al f an ho u r st ir i t w e ll an d t ran sfer t h e m ix t u re t o a
,

w e ll c lo sed v e ssel an d per m i t i t t o re m ai n fo r s i x or

,

eigh t ho u r s st irri ng i t o ccas io nall y an d t he n fil t er i t

, ,
 1 60 ELI X IR F O RM U LK
E .

EL I X I R O F B RO M I D E O F S O D I U M .

B rom i d e of S od i u m 2 56 g ra i n s

S i m p l e El i x i r 1 6 flui d ou n c e s

D i ssol v e bro m id e o f s odi u m i n t h e s i m pl e e lixir

th e ,

an d fil t er i f n e c e ssary .

u id drach m
E h
”
ac fl ( t e as poo n fu l
) o f t h e fi n i s h e d eli xir

c o n tai ns t w o grai n s o f bro m id e o f s odi u m .

EL IXI R O F I O D I D E O F S O D I U M .

I od i d e of S od i u m 2 56 g ra i n s
S i m p l e El i x i r 1 6 flu i d ou n c e s

i ssol v e t h e I od ide o f s odi u m i n t h e s i m pl e e lixi r an d

D ,

fil t er i f ne ce ssary .

Each fl u id drach m ( t e as poo n fu l) o f t h e fi n i sh e d e lixir

c o n tai n s t w o grai n s o f iodide o f s odi u m .

S QU I R E S E L I XI R
’
.

O pium 4 t roy o u n c es

C am p h o r 1

C o c h i n e al 1

O i l F en n e l S e e d fl u i d d ra c h m s
2

T i n ct u re S e rp e n t a ri a 16 fl u i d ou n c e s
S p i ri t A n i s e 1 6
W a t er 2

Red u c e dr u g s t o a c o ar se po w d e r H av i ng pre v i
the .
~

o u s l y di ss ol v ed t h e oil o f fe n n el seed i n t h e s piri t o f an

i se an d m ixed t hi s w i t h t h e w at e r add t h e po w d e red ,

dr u g s and t h e t i nc t u re o f se rpe ntar ia Macerat e fo u r .

t ee n d ay s s t irri ng th e m i x t u r e t horo u ghl y e ach d ay ;

,

S upp l e ment to ti l e Lona on P /zan n acopcc i a

’
t h e n fil t er .
,

1 82 1 .

The origi nal for m u l a in th e abo v e w ork c o n tai ns si x

 ELI XIR F O R M U Li E . 16 1

o u nc e s o f A u ru m M u si v u m ( su lph u re t of ti n ) ,
w h i ch

we l eav e o u t .

ST . H U B ER T H U N T E R S E L I x rR
’
S
’
.

( EL1 x 1 R D E ST . H U E R T P UR
B OC H A E UR )
LE S SS S .

C a rb ol i c A c i d 1 t roy ou n ce

A l coh ol

M ix t he m t oge t her .

E ach fl u id drach m co ntai ns abo u t t w o and o ne -

fo u rt h
m i n i m s o f carbol i c acid .

( C A S S E L L M A N , fro m N e w Rem ed i e s,

EL I XI R O F S TI L L I N G I A .

F l u i d E x t ra ct of S t i l l i n gi a 2 flui d ou n c es

S i m p l e El i x i r
A l c oh o l
C arb on at e of M ag n e s i u m , a s u ffi c i en t q u an t i t y .

Tri t u rat e t h e fl u id ex t ract o f st illi n gi a i n a cap acio u s

m ort ar w i t h carbo nat e o f m ag n e s i u m i n am o u n t s u ffi
,

c ie n t t o for m a c re am y m i x t u r e ; t he n grad u all y ad d t h e

s i m ple elixi r s t irri ng w ell an d fil t er

, ,

CO M PO U ND EL IXI R O F S TI LLI N GIA .

F l u i d E x t ra c t of S t i l l i n gi a , C o m p o u n d 2 flu i d ou n ce s

S i m p l e El i x i r
A l co h ol
C arb on at e of M a g n es i u m , a s u ffi c i e n t q u a n t i ty .

Tri t u rat e t h e fl u id e x t ract o f st i lli n gi a co m po u n d w i t h

carbo nat e o f m ag n e s i u m i n s u ffi c ie n t am o u n t t o for m a

c re am y m ix t u re ; t he n grad u all y ad d t h e s i m ple elixir ,

s t i rri n g w ell and fil ter

, Last l y m i x th e fi l t rate w i th t h e
.
,

al c ohol .

14
1 62 ELI x I R F O R M U LJE .

E ac h fl u id drach m ( t easp oo n fu l ) o f th e fi ni shed elixi r

w ill c o n tai n s u ch an am o u n t o f se v e n an d a h al f m i n i m s
o f fl u i d ex t ract o f c o m po u n d s t illi ngi a m i x t u re as t h e

m en st ru u m i s cap able o f di ss ol v i ng .

S TO M A C H I C EL I XI R .

( E LXR
I I ST O M A C H I C L M ) ‘

G en t i a n 2 t roy o u n c e s

C u r a c ao O ra n g e P e e l
V i rg i n i a S n ak e - root
C o c h i n ea l g ra i n s
B ra n d y 2

M i x t h e dr u g s red u ce t he m t o a co ar s e po w der
an d ,

an d m acerat e t h i s i n t h e br an d y fo r fo u r t ee n d ay s s ti r ,

ri ng t h e m ix t u re t horo ughl y e ach d ay t he n fil t er .

S W E E T E L I XI R O F V I T R O L .

( EL1 x 1 R V I T R I O LI D ULC E ) .

A rom at i c T i n ct u re
D u l ci fi ed S p i ri t of V i t rol

M i x t he m t oge t her .

( Lo n d o n P h ar maco p oei a,

S TO U G H TO N S EL I XI R
’
.

G e n t i an 2
% t roy ou n c es

S e rp e n t ari a
B i t t e r O ra n g e P e e l
C al am u s
D i l u t e d A l c oh ol

Red u ce th e dr u g s t o a co arse po w d e r an d m acerat e ,

t hi s i n t h e d il u t ed al c ohol fo r fo u r t ee n d ay s st irri n g t h e ,

m ix t u re t horo u ghl y eac h d ay ; t h e n fil t e r .

(S u ppl e m en t t o t h e Lo n d o n P h ar mac o p oei a . )

1 64 EL I XIR F O R M U LAZ .

i ngredie nt s an u n s igh t l y m ix t u re re s u l t s pro v idi n g th e

, ,

fl u id ex t ract o f s u m b u l w as made w i t h al cohol an d w as

l l Ot an aq u eo u s i n fu s io n H e n ce th e dire ct io ns w e h av e
.

gi v e n are for t h e p u rpo se o f prod u ci n g a pre se ntable

liq u id .

Each fl u id d rach m r e pre s e n t s abo u t fo u r m i n i m s o f

fl u id ex t ract o f su m b u l an d t hir ty si x m i n i m s o f eli x ir o f -

v aleri anat e o f amm o n i u m .

EL I XI R O F T A R .

P i n e T ar 5 t roy ou n ce s

S u gar 1 5
D i l u t ed A l coh ol I oo flui d o u n c es

Tri t u rat e th e t ar and s u gar t oge t h er t he n w i t h t h e ,

al cohol an d fil t er ,
.

Thi s w as su gg e st ed b y M agn e s Lahe n s i n t he I tal i an ,

C/zemi cal Gaz ette I n re ali ty i t i s s ol u t io n o f tar i n dil u

.
,

t ed al c ohol and doe s n o t co n for m t o t h e m oder n A m er i

,

can elixir .

E L I XI R O F T A R C O M P O U N D .

W ine of T ar 16 flu i d ou n ce s

S y ru p of W ild C h e rry 4
S y ru p of T ol u 4
M e t h y l i c A l c o h ol I

S u l p h at e of M orp h i n e 4 g ra i n s

D i ssol v e th e su lphat e o f morphi ne i n t h e w i ne of tar ,

an d t he n ad d th e o t her i ngre die nt s .

( N on -
o ffi c i n al f or m u l ae i n l o c al u se , c o m pil e d an d p u b li s h e d by t h e Jo i n t C o mmi t t e e o f
th e M ed i cal an d P h ar mac eu t i c al A s s oc i at i on s of t h e D i s t ri c t of C o l u mbi a )
.
 ELI XIR F O R M U LIE .

EL I x I R O F T H U J A O C C I D EN T A L I S .

( EL1 x1 R or A R R BO V I T JE )
.

F l u i d Ex t ract T h uj a O c c i d en t a l i s 2 flu i d ou n c es

S i m p l e El i x i r
A l c o h ol
C ar b o n a t e of M ag n e s i u m , a s u ffi c i en t q u a n t i ty .

Tri t u ra t e th e fl u id ex t ra ct o f t h uj a w i th carb o na t e o f
m ag n e s i u m u n t il o f a crea m y c o ns i st e nce ; t he n grad u all y
ad d t h e s i m ple elixir fil t er an d add th e al c ohol A
, ,
.

fo rm u l a for elixir o f t h uj a o cc ide n tali s w as propo sed by

M r W H Law s i n N ew Re m edie s 1 8 77 T h i s i s o n e
”
. . .
.
, ,

o f t h e cla ss o f su b stan c e s w h i c h i n o u r opi n io n can n o t

, ,

be sat i sfa ct oril y exh au st ed b y m e ans o f an aq u eo u s m en

s t ru u m . The ch a ract eri st i c pri n c iple s o f t h uj a are oil y
an d re s i n o u s an d t he se are l argel y pre cipi t at ed b y any
,

aq u eo u s liq u id .

Each fl u id drach m o f t h i s elixir repre se nt s l ess th e ,

s u b s tan ce s pre cipi tat ed b y t h e s i m ple elixir s e v e n and a ,

h al f m i n i m s o f fl u id ex t ract o f t h uj a o cc ide n tali s .

E L I XI R O F V A L ER I A N .

F l u i d E x t ract of V al e ri an 2 flu i d ou n c es

S i m p l e El i x i r
A l c oh ol
C a rb on a t e of M ag n es i u m , a s u fli c i en t q u an t i ty .

Tri t u rate t h e fl u id ex t ract o f v aleria n i n a capa cio u s

m or tar w i t h carbo nat e o f m ag ne s i u m i n am o u n t s u ffi
,

cie n t t o for m a c rea m y m ix t u re ; t he n grad u all y ad d t h e

s i m ple elixir st irri n g w ell

, an d fil t er Lastl y m i x th e
, .
,

fil t rat e w i t h th e al cohol .

E ach fl u id drach m o f t h e fi n i shed elixir w ill co n tai n o f

se v e n an d a hal f m i n i m s o f fl u id ex t ract o f v al e rI an su ch

an a m o u nt as t h e m e nst ru u m i s cap able o f di sso l v i ng

 ELI XIR F O RM U LIE .

MYN I C H T S EL I XI R O F V I TRI O L
’
.

Thi s ancie nt elixir h as bee n m odified an d de s erv edl y , ,

t i m e an d agai n u n t il e x c ep t i n g t h e su lph u ri c ac id i t
, , ,

s car cel y r ese m ble s i t s for m er s el f I t w as m ade b y t h e

.

L o n do n and Edi nb u rgh Ph ar macop oei as pre cedi n g 1 770 , ,

as follo w s

3 d rach m s
3
3
I t roy o u nces

2 d rach ms
2

Red u ce th ese i ng red i en ts i n to a p o w d er, to w h i ch add Of

3 t roy ou nces

D i ges t th em togeth e r for tw en ty d ays, an d th en fi l ter th e ti n c tu re fo r

u se .

The Edi nb u rgh Phar m acop oei a 1 770 i m pro v e s u po n , ,

t hi s pro ce ss m odi fy i n g i t u n t il t h e prod u ct re se m ble s o u r

,

for m er aro ma t i c sul ph u ri c acid ( elixir v i t riol ) U S P , . . .

,

t h e propor t io n o f s u lph u ri c ac id bei ng red u ced v er y

“
c o n s iderabl y Tho se w h o m ake Elixi r o f V i t riol at
.
”

t h e pre s e n t t i me w ill fi n d i n o u r Ph ar m ac op oei a o f 1 8 8 2 a

pro cess w h i ch i n o u r opi n io n i s v er y m u ch su peri o r t o

, ,

an y h ere t o fore su gge st ed an d t h i s ol d fo rm ul a i s s i mp l y

,

a cu rio si ty .
1 68 ELI X IR F O R M U L/E .

EL I X I R O F W AHO O .

F l u i d E x t ract of W ah oo 2 flui d ou n c e s

S i m p l e El i x i r
A l co h ol
C arb o n at e of M agn es i u m , a s u fl i c i en t q u an t i t y .

Tri t u ra t e t h e fl u id ex t ract o f w ahoo w i t h carbo n at e ,

o f m ag n e s i u m i n su ffi c ie n t am o u n t t o for m a c re am y
.

m ix t u re ; t he n grad u all y add t h e s i m ple elixir st irri n g ,

w ell an d fil t er
, Last l y m i x t h e fil t rat e w i t h t h e al cohol
.
, .

Each fl u id dra ch m o f t h e fi n i shed elixir w ill c o n tai n

t h e m edi ci na l pri n ciple s o f s u c h an am o u nt o f s e v e n an d
a h al f m i n i m s o f fl u id ex t ract o f w ahoo as can be re

tai ned i n s o l u t i o n by t h e m e n st r u u m .

EL I X I R O F YER B A S AN T A .

F l u i d E x t ract of Y erb a S an t a 2 fluid o u n c es

S i m p l e El i x i r
A l coh o l
C a rb o n at e of M ag n es i u m , a s u ffi c i e n t q u an t i ty .

Tri t u rat e t h e fl u id ex t ract o f y erba san ta i n a cap ac io u s

m or t ar w i t h carbo nat e o f m ag n e si u m i n am o u n t s u ffi
,

c ie n t t o for m a c re am y m ix t u re ; t he n gr ad u all y add t h e

s i m ple elixir st i rri n g w ell

, an d fil t er, L ast l y m i x t h e .
,

fil t rat e w i t h th e al cohol .

Thi s elixi r h as bee n re c o m m e nded as a v ehi cle fo r ad

m i n i s t eri ng q u i n i ne and i s said to di sg u i se i t s bi t t er ne s s
, .

A pro ce ss was de v i sed b y M r Jas S M cC l eary w here . . .

,

b y aro ma t i cs w ere added an d w hi ch w e gi v e i n su b

,

s tan c e u n der c o m po u n d elixir of y erba san ta Y erba .

s an ta co n t ai n s a pe cu li ar sw ee t ast ri nge nt pri ncipl e

w hi ch m ay p re c ipi tat e t h e q u i n i n e t h u s re n deri n g i t i n
,

s ol u ble . Care s ho u ld be take n t h at t h e m i x t u re b e no t

fil t e red afte r t he ad d i t i o n o f the q u i n i ne .
 ELI XIR F O R M U LZE . 1 69

CO M PO U N D EL I XI R O F YER B A S A N TA .

F l u i d E x t ra ct of Y e rb a S an t a 2 flui d ou n c es

F l u i d Ex tract of S w ee t O ra n g e P ee l
F l u i d E x t ra c t of C i n n am on
F l u i d E x t ra c t of C l ov es
S i m p l e El i xi r
R e d S au n d e rs g r a i n s

C a rb on at e of M ag n e s i u m , a s u ffi c i e n t q u an t i t y .

M i x t h e fl u id ex t rac t s ,
ad d red
der s and t ri t
th e sau n ,

u r at e i n a cap ac i o u s m or tar w i t h s u ffi c ie n t carbo nat e o f

,

m ag n e s i u m t o for m a c re am y m ix t u re ; t he n grad u all y

ad d t h e s i m ple elixi r s t irri n g w ell an d fil t er
, , .

Thi s pre p arat io n i s u s ed fo r di sg u i s i n g t he tast e o f q u i

n i ne S e e o u r re m ark s u n d e r e lixir o f y e rb a santa )
(
. .

EL I XI R O F V A L E R I A N AT E O F Z I N C .

V al eri a n a t e of Z inc 64 g ra i n s

D i s t i l l ed W at er 6 flui d ou n c e s

S i m p l e El i xi r 9

Tri t u rate t h e v aleri anat e o f z i n c w i t h t h e w at er an d

t he n ad d t h e s i m ple elixir Wh e n s ol u t io n o f t h e s al t
.

r es u l t s fi l te r t h e liq u id S ho u ld t h e v aleri anat e o f z i nc

.

re fu se t o di ss ol v e cau t io u s l y drop i n a li t t le h y dro chlori c

,

ac id car e b e i ng t ake n t h at o n l y e n o u gh t o e ffe c t i t s s ol u

,

t io n i s add ed .

E ac h fl u id dra ch m ( teaspoo n fu l ) o f th e fi ni sh e d elixi r

c o n t ai n s o n e an d a h al f gr ai n s o f v al eri anat e o f z i nc .
 1 70 EL I XIR F O R M U LE .

A DD E N D A .

L R
E IX I L Y O F CA IS A A.

We s t at e d in t he fi r st ed i t i o n o f o u r f t h ese
wor k (see pg a e 1 6 t h at
“ th e fi r st o
p p r e ar a t i o n s w h i c h t h e w r i t e r c a n r ec al l w as t h r o w n u o n t h e m ar e t i n t h i s c i t y p k
( C i n c i n n a t i ), a b o u t 1 8 62 u n d e r t h e n am e C o r d I al Eli x I r o f C al s a y a an d i n a oo t i f
n ot e w e r e ma r t h at
“
,

k
the rs t u bli s h e d fi p
o r m u l a t h a t w e c an fi n d fo r a n
y of th i s f
c l ass o f p p
r e a r a t i o n s u n d e r t h e n am e e l i x i r , i s t h e o r m u l a w e g i v e fo r El i x i r o f C al i f
say a, b y M r A l r e d B T a y l o r , f f
r o m t h e j ou r n a l of P h a r m a cy , Jan u a r y , 1 8 5 The
f f
.

D m g gi r tr C i r c u l a r o f s a m e d at e s t at e s t h at u p t o t h at t i m e n o or m u l a or t h at
’
’

p
p r e ar at i o n h ad b e e n ub l i s h e d p
fi
.

O u r h i s t o r i c al r e v i e w w i l l h a v e t o b e m od i e d t o an e x t e n t A l t h o u g h w e c on
p f g k
.

s u l t e d s e v er al o l d h a r mac i s t s b e o re i ss u i n t h e w o r , w e fi n d t h at e h x i r s an t e d at ed
t h e t i me n am e d b y m an y y e ar s H o w e v er , t h e y d i d n o t c o m e i n t o g e n er al u s e u n t i l
.

the o r l o d n am e d b y u s
B f p g k f
.

rof P W e d or d , u o n r ev i e w i n t h e bo o , k i n d l i n o r m e d u s t h at o n e of t h e
p p p
. . .

o u l ar e l i x i r s o f t h e r e s e n t d ay i s a d v e r t i s e d t o h av e ee n i n t ro d u c e d I n t h e y ear
1 8 3 0 , an d w e h av e s i n c e c o r r o b or a t e d t h e e v i d e n c e O u r r e s e c t e d r i e n d M r C h as f
p
.
, .

A H e i n i st h , w h o d o u b t l ess i s o n e o f t h e o ld e s t , as h e i s o n e o t h e ab l e s t , h ar m ac i st s ,
f k pp f
.

w r o t e 11 5 s h o r t l y a t e r t h e b o o a e a r e d , as o l l o w s :
“
I se n d y o u a C o p o f an o l d l ab e l fo r a C o r d ial El i x i r o f
‘
u inin e my a t h e r Q ’
f
fo rm erl y mad e T h i s l a c l I r e m e m b e r a
. e ar e d o l d w h e n I pp
r s t w or e d i n t h e s t o r e, fi k
i n 1 83 8 . H ow l ong i t h ad b ee n u s e d , i s m o r e t h a n I c an s ay o r r e m e m b e r I h ad l os t .

si g h t o f i t u n t i l I r ead t h e n o : i c e t h at y o u c o u l d fi n d n o r e c or d o f el i x i r o f c al i sa a be
fo r e t h e y ear 1 8 59 T h i s C o r d i al Eli x i r o f C al i sa a w as c o m o se d o f u i n i n e , c o v es , p q
p p g
.

ci n n am o n , bi t t e r o r an e e e l , c a s i c u m s u ar a n d i l u t e al c o h ol
p g k f
.
,

M r H ei n i s t h e nc o s e d u s a c o y o f t h e o r i i n al l ab e l , t a e n r o m o n e o f t h e b o t
i
t l es w h c h w as i n t h e c e l l ar o f t h e S t o r e i n 1 8 3 8 W e t a e t h e l ibe r t t o r e p z o d u c e i t , k
p
.

an d o u r r ead e r s w ill n o t e t h a t i t cl os e l y r e s e m b l e s t h e e li x i r l ab e l s 0 t h e r e s e n t d ay :

C RD L
O IA E LI x I R o r U N NE Q I I .

p p
T h i s e x c e ll e n t r e ar a t i o n i s a r t i c u l ar reco e n ed t o p
e r s o n s O f d el i c at e ly mm d p
h abi t an d w e a s t om ac h k I t i n c r e ase s t h e a e t t e, ac t at e s d i g e s t i o n , a n d i s w e l l pp i f i l i
p p g g f
.

ad a t e d t o al l e r so n s l i v i n i n l o w a n d m ar s h y c o u n t r i e s, w h e r e a u e a n d e v er p r e
v ai l , a n d a l so fo r t h os e w h o a r e e x o s e d t o d am an d w e t w e a t h e r p
I t i s ta e n w i th p k
p k f g p p
.

s u c c e ss b y e rso n s w ea e n e d b e v e r an d a u e, or b y a c o i o u s e r s i r at i on p r o
d u c e d b y t h e h eat o f s u m m e r e r so n s r e c o v e r i n ro m b i l i o u s e v e r 5 o u l d u se i t gf f
p p f g f k
.

fr e e l y , t o re v e n t a r e l a s e F r o m h al a w i n eg l as s t o a w i n e l ass u l i s t o be t a e n
on c e o r t w i c e a d ay , as o c c as i o n m ay re u i r e q
p g
.

P r e are d an d s ol d by Jo h n T H e i n i s t h , D r ug i s t , Eas t K i n g S t , La n cas t er, Pa . . .

O ur at t e n t i o n h as b ee n c al l e d t o t h e f ll wi g o o n o mi ssi o n s :

E L X R M LT
I I or A
fl
.

F l u i d Ex t r ac t of M al t 8 uid o u n c es
p fl
,

Si m l e El i x i r , 8 uid o u n c es

Mix g t h em to et h er Eac h fl ui d d r ac h m (t easp oo n f ul ) of t h i s el i x i r r e p r e se n t s

f fl
.

t hi t y mi i m
r n s o u i d e x t r ac t o f mal t
p f p f p
.

If t a e as oo n u l m al t i s m i x ed w i t h a t abl e s o on u l of s t arc h
of el i x i r o f ast e
m d b b i li g
a e o n one p
ar t o f s t ar c h w i t h s i x t e e n ar t s o f w a t e r , t h e m i x t u r e w i l l i m p
fl
m e d i at e y bec o m e u i d at a t e m e rat u r e o f 1 50 F ah °
I n rom t e n t o p t e e n m i n u t es f fif
f p pp
.

t h e m i x t u r e w i l l ai l t o ro d u c e a bl u e c o l o r w h e n d r o e d i n t o d i l u t e so l u t i o n of
V
i o d i n e ( o l u m e t r i c S ol u t i o n o f I o d i n e , U S P ) . . .

EL X R I I OF M LT A A ND I R N O
fl
.

El i x i r of M al t 8 u i d o u n c es
p fl
,

Eli x i r of P h o s h at e of I r on , 8 u i d o u nc es

M i x t h em to g e t h e r an d filt
d r ac h m ( t eas oo n u l ) c on
er if n ec e ss ar y Eac h fl ui d p f
fif fl fg p p
.

t ai n s t ee n m i n i ms o f u i d e x t r ac t o f m al t , an d o n e -h al ra i n of h o s h at e o f i r o n
g p p
.

N ew R em ed i es fo r A u u s t , 1 8 8 3 , c o n t ai n s a fo r m u l a fo r t h i s r e ar a t i o n , w h i c h i s
e s se n t i al l y t h e s am e as t h a t w e iv e g
W e m o d i y i t s o m e w h a t , i n o r d e r t h at i t s h al l f
f p p k k
.

co n o rm t o t h e o t h e r re ar a t i o n s o f o u r w or of a l i e n at u r e .

EL X R I I OF M LT A A ND P E N PS I
i i fl
.

El x r of M al t , 8 u d
i ou n c e s
E11 x 1 r of P e p sm , 8 fl u Id o u nc es

M ix
t h e m t og e t h e r Eac h u d d r ac h m ( t e as oo n u l ) o f t h e
p . fl i
n i s h e d e li x i r c on f fi
i
tai n s o n e g r a n of s acc h ar at e d p e p s m an d fi ft e en m n ms of u i d ex t rac t of mal t . i i fl
 1 72 I ND E X .

C o m p o u n d t i n c tu r e o f al oes 1 5—1 2 7 . El i x i r o f al oes an d r h u b arb .

C o m p o u n d t i n c t u r e o f g en t i an 15 . El i x i r am ar u m
C o m po u n d t i n c t u re o f al a p 43 j . El i x i rs , Am er i c an
C o m p o u n d t i n c t u re o f s en n a 1 1 —1 57 El i x i r o f amm o n i o c i t rate o f b i s
-

C o n t i n uo u s p r ec i p i tat i o n i n e l i x m u th
i rs 2 4 —2 5 El i x i r o f amm o n i o c i trate o f -

C o r d i al el i x i r o f c al i saya o r c i n b i s m an d i r o n p y r o p h
.

ch ona El i x i r o f am m o n i o c i t r ate o f
-

C o r d i al v s e l i x i r . b i s m an d p ep si n
.

C r i t i c i s m s o n e l i x i rs El i x i r o f am m o n i o c i trate of -

C r i t i c i sms o n v ari e ty o f el i x b i sm , p ep s i n an d s t ryc h n i n e

.

i rs 2 6- 2 7 El i x i r o f am m o n i o c i t r ate o f
-

b i s m an d st ryc h n i n e
—
.

El i x i r o f amm o n i o -c i t r ate o f
'

D afi e y s e l i x i r
’
14 91
V i l l e t te s g o u t e l i x i r i ron
’
D e

D e r i v at i o n o f t h e w o r d e l i x i r El i x i r o f am m o n i u m b ro m i d e .

esl au r i e r s e l i x i r o f cal i sa a El i x i r o f am m o n i u m - c i t rat e,

’
D y
i r o n c h l o r i d e an d w i ld c h e r ry
D es l a u r i e r s
’
to n i - fe b r i fu ge an El i x i r o f amm o n i u m v al er i an ate
q ui n q ui na et c afé El i x i r o f am m on i u m v al er i an
D e tan n a te d el i x i r of b ar k . at e an d c i n c h o n i d i n e

D etan n ated e l i x i r o f c al i sa a
y or El i x i r o f am m o n v al e ri an ate
.

c i n ch o n a an d c i nc h o n i n e

D i eh l s d e tan n ate d e l i x i r o f cal

’
El i x i r o f am m o n v al er i an a te,
.

i saya c i n c h o n id i n e an d c i n c h o n i n e,

D i eh l , Pro f C Lew i s, an d el i x
. . El i x i r o f am m o n v al er i an ate,
.

ll S c i n c h o n i d i n e c i n c h o n i n e an d
’

D i l l y s d affy s t r ch n i ne
’
y
D r B u t l er s e l i x i r o f b r an d y
.
’
. El i x i r o f amm o n v al er i an ate,
.

D r H ar tsh o r n e s c h l o r o fo rm c i n ch o n i d i n e an d i ro n p y
’
.

a e o ri c r o p h o s ph at e
p r
g
D u l c i fi e d sp i r i t o f v i t r i o l El i x i r o f am m o n v al er i an ate ,
.

c i n c h o n i d i n e , i ro n p y ro p h o s

Eb er t, A E , an d el i x i r s h a t e a nd s t r c h n i ne
. .
p y
El i x i r o f ac e t at e o f C h i n o i d i n e . El i x i r o f am m o n v al eri an ate ,
.

El i x i r o f ac e t ate o f m ag n esi u m c i n ch o n i n e an d i ro n p yro

an d r h u b ar b h o s h ate
p p
El i x i r o f acet ate o f p o t ass i u m . El i x i r o f am m o n v al er i an ate,
.

El i x i r o f ac et ate o f po t assi u m c i n ch on i ne an d s t r ch n i n e
y
a n d b u ch u El i x i r o f amm on v al er i an ate
.

El i x i r o f ac e tate o f p o tassi u m an d i ro n p y r o p h o s p h a t e

j u n i pe r an d b u ch u El i x i r o f am m o n v al eri an ate
.

El i x i r o f ac i d arsen i o u s, h yd r o an d m u sk r o o t

c h l or. q u i n i n e an d i ro n ch l o El i x i r o f amm o n v al er i an ate

.

ri d e an d q u i ni n e

E l i x i r o f ac i d sal i cy l i c E l i x i r o f am m o n v al e r i anate,
.

El i x i r o f ac i d u m H al l er i u i n i n e an d c i n c h o n i d i n e
q
El i x i r adj u v an s El i x i r o f am m on v al er i an ate,
.

El i x i r al b u m q u i n i ne, c i n ch o n i d i n e , i r on
El i x i rs al k al o i d al r o h o s h ate a n d s t c h
py p p r
y
El i x i r o f al o es n i ne
 IND E X . I 7S

El i x i r of ammo n . v al er i an ate , El i x i r o f b ark , st ryc h n i n e an d

q ui n i n e , c i n ch o n i d i ne an d b i s m , fer r ate d
s t r yc h n i n e 3 8 El i x i r o f b a rk an d s t ry c h n i n e ,
El i x i r of am m o n . l i
v a e r an at e,

q u i n i n e an d c i n c h o n i n e .
39 El i x i r o f b e ef
El i x i r of am m on . l
v a er i an at e , El i x i r o f b ee f, c i t r ate o f i r o n
q u i n i n e, c i n ch o n i n e an d ca l i saya an d s t r c h n i n e
y
s t r yc h n i n e El i x i r o f b eef an d i ro n
El i x i r of am m o n . v al e r i an a te, El i x i r o f b eef, i ro n an d c al i
q u i n i ne an d i r o n p yr o p h o s saya

p h at e 40 El i x i r of b ee f, i ro n an d ci n

El i x i r o f am m o n v al er i an at e,
.

q u i n i n e , i ro n py pr o h o s h at e
p El i x i r of b ee f, i ro n , c i n c h o n a
an d s t r yc h n i n e an d s t ry c h n i n e

El i x i r o f a mm o n v al e r i an ate
. El i x i r o f b eef an d i r o n c i t r ate .

q u i n i n e an d s t r y ch n i n e El i x i r o f b eef, i r o n c i tr a te an d
El i x i r o f am m o n v al e r i an ate . cal i say a

an d s t r y c h n i n e El i x i r o f b i sm u t h
El i x i r o f a m m o n v al er i an at e
. El i x i r o f b i s m u t h an d am m o n
an d s u m b u l . i u m c i t r ate .

El i x i r an t i g l ai reu x Eli x i r o f b i sm u t h , am m o n i o
El i x i r o f an t i g o u tte u x d e V i l c i t rate an d i ro n p y ro p h os
l e t te p h a t e

E l i x i r o f ar b o r v i tae El i x i r o f b i sm u t h am m o n i o
El i xi r ar o m at i c c i t r ate an d
p pe si n

E l i x i r o f ar sen i c El i x i r o f b i sm u th am m o n i o
E l i x i r o f ar se n i c i od i d e an d -
c i t r ate, e
p p s i n a n d s t r
y c h n i n e
m er c u ry El i x i r o f bi sm u th am m o n i o
El i x i r o f arsen i c , i r o n an d q u i c i t r ate an d s t r c h n i n e
y
El i x i r o f b i sm u t h an d b ar k , fer
El i x i r o f arsen i ou s ac i d , h yd ro
ch l o r . q u i n i ne an d i r o n c h l o El i x i r of b i sm u t h , b ar k an d
r id e 1 08 i r on
El i x i r o f ar se n i te o f o tass i u m 1 48 El i x i r o f b i sm u t h , c al i saya an d
p .

El i x i r o f ar sen i t e o f s o d i u m i ro n
59
1
El i x i r ast h m at i c u m 138 El i x i r o f bi s m u t h , c al i saya, i ro n
El i x i r ofb ar k 6 7—68 py p r o h o s h ate an d
p a m m o n .

El i x i r o f b ar k an d b i s m , fer . c i t rate

r at ed . El i x i r o f b i s m u t h , c i n c h o n a,
El i x i r o f b ar k , d e tan n ated . i ro n an d s t ry c h n i n e
El i x i r o f b ar k an d i r o n El i x i r o f b i s m u t h , fe r r at ed
El i x i r o f b ar k , i ro n an d h i s E l i x i r o f b i s m u t h an d i ro n
m u th . E l i x i r o f b i sm u t h i ro n an d c i n
El i x i r o f b ar k , i ro n an d p e p ch o na

El i x i r o f b i sm u t h , i ro n an d ep
p
El i x i ro f b ar k , i ro n p ro to
x i de

an d s tr yc h n i n e 75 El i x i r o f b i sm u th i r o n p yro
,

El i x i r of b ar k , i ro n an d s t r y c h p h o s p h at e , c a l i sa a
y a n d
79 s t r
yc h n i n e

El i x i r of b ar k , i ro n , s t r yc h El i x i r o f b i sm u t h , i ro n , st ryc h
n i ne an d b i sm .
77 n i n e an d b ar k
 I 74 IND EX .

El i x i r o f b i sm u th and p eps i n ” El i x i rs, c a l i saya

El i x i r o f b i sm u t h , pe psi n and El i x i r o f c a l isaya al k a l o i d s
i ro n pyro ph osp h ate El i x i r o f c al i saya b ar k and i r o n
El i x i r o f b i sm u th , pepsi n an d El i x i r o f c al i saya an d cal c i u m
q u 1n 1 n e l ac to p h o sp h ate
-

El i x i r o f b i sm u th , pe psi n an d El i x i r o f cal i saya, c i trate o f i ron

p h o s p h a t e o f uqi n i n e p ro to x id e an d s t r c h n i ne
y
El i x i r o f b i sm u t h , p pe s i n El i x i r o f c al i saya an d c i trate o f
s t r ch n i n e an d i r o n ro to x i d e o f i ro
y .
p
El i x i r o f b i sm u t h , p y ro p h os El i x i r o f cal i saya and co ffee,
h of i i n an d D esl au r i er s ’
p a t e r on,
p pe s 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

s t ryc h n i n e El i x i r o f c al isaya, d e tan n ated

q
El i x i r o f b i sm u th , u i n i n e, p ep El i x i r o f c al i saya, fe r rated
s i n an d s t ryc h n i n e El i x i r o f c al i saya and ferr o u s
q
El i x i r o f bi sm u th , u i n i ne p h os c i trate .

p h a t e a n d s t r y chni ne El i x i r o f c al i saya, fer ro u s c i t rate

El i x i r o f b i sm u th , strych n i n e an d s t r yc h n i n e
an d b ar k , fe r r ated El i x i r o f c al i saya, i ro n an d b ee f
q
El i x i r b i su l p h ate o f u i n i n e . El i x i r o f c al i saya, i r o n and h i s
El i x i r, b i t ter m u th
Eli x i r o f b l ac k b e r r y Eli x i r o f c al i saya an d i ron c h l o
El i x i r o f b l ack co h osh , co m r id e

p o u n d El i x i r o f c al i saya, i r o n ch l o r i d e
El i x i r o f b ol d o and amm o n -c i t r at e
.

El i x i r o f b ran d y El i x i r o f c ali saya, i ro n ch l o r i d e,

El i x i r o f b ro m i d e of am m o n amm o n -
c i t rate an d
.
g en t i an ,

i um El i x i r o f c al i saya, i ro n c i t rate
El i x i r o f b rom i d e o f cal ci u m an d b eef
El i x i r o f b ro mi d e o f i ro n El i x i r o f c al i saya, i r on ci trate,
El i x i r o f b rom id e o f p o tass i u m , b ee f an d st ryc h n i ne
Eli x i r o f b ro m id e o f u i ni n e q El i x i r o f c al i saya, i ro n and ge n
El i x i r o f b ro m i d e o f sod i u m . t i an
El i x i r o f b u ch u . Eli x i r o f c al i saya, i r o n an d p ep
j
El i x i r o f b u ch u , u ni per an d sm .

ace tate o f p o t assi u m El i x i r o f c al i saya, i r on p ro to x

El i x i r o f b uc h u an d p arei ra i d e an d s t ryc h n i n e
b rav a El i x i r o f c al i saya a nd i ron p yro
El i x i r o f b u ch u an d po tassi u m p h os p h a t e

acetat e El i x i r o f c al i saya, i r on pyr o

El i x i r o f caffei n e c i t rate p h osp h a te , amm o n i o-c i t rat
e

El i x i r o f c al ci um , b ro m i d e o f . an d b i sm u th
El i x i r o f cal c i um , i o d o b ro m i d e
-
El i x i r o f cal i saya, i ron p y ro
p h os p h at e , b i s m u th an d

El i x i r of cal c i u m l ac to p h o s
-
s trych n i n e

p h a t e El i x i r of cal i saya, i ron pyr o

El i x i r o f cal ci u m l ac to p h os
-
p h o s p h ate an d l i m e l ac to
p h at e an d c al i s aya p h osp h ate

El i x i r o f cal ci u m l ac to p h o s -
El i x i r o f c al i saya, i ro n pyro
p h a t e , i ro n py pro h o s p h at e p h o sp h at e an d p e p si n

an d c al i saya El i x i r of c al i saya, i ro n pyro

El i x i r of cal i saya p h o s p h ate an d s t r yc h n i n e .
 1 76 I ND EX .

El i x i r of c i n ch o n i d i n e, i r on El i x i r of c ncih on i n e , c i n ch on i
p h os p h a t e , q u i n i ne an d d i n e an d v al e r i an ate o f am m o
s t r yc h n i n e

El i x i r o f c i n ch o n i d i n e an d i r o n El i x i r o f ci n ch o n i n e an d i ro n
r o h o s h at e ro h o h a t
py p p p y p s
p e

El i x i r o f c i n c h o n i d i n e, i ro n El i x i r o f c i n c h o n i n e p h osp h at e
r o h os h a t e a n d t r ch an d p e psi n
py p p s y
m na El i x i r o f c i n ch o n i n e p h o sp h ate
El i x i r o f c i n c h o n i d i n e, i r o n p pe s i n a n d s t r
ych n i ne

q u i n i n e an d s t r c h n i n e
y El i x i r o f c i n c h o n i n e , q u i n i n e,

El i x i r o f c i n c h o n i d i n e , i r o n an d amm o n . v al e r i an at e an d
s tr yc h n i n e s t ry ch n i n e

El i x i r o f c i n c h o n i d i n e p h o s El i x i r o f c i n c h o n i n e, q u i n i n e,

p h a t e i ro n py ro -
p h o s
p h at e a n d
El i x i r o f c i n c h o n i d i n e p h os s t r y ch n m e
0

p h a t e a nd
p e psi n El i x i r o f c i n c h o n i ne an d q u i
El i x i r o f c i n c h o n id i n e p h os n i n e p h o s h ate
p .

p h a t e , p p
e s i n an d s t r c h n i n e ,
y El i x i r o f c i n c h o n i n e an d st r yc h
q
El i x i r o f c i n c h o n i d i n e, u i n i n e ni ne
p h o s h ate
p .

an d am m o n v al er i an at e
. . El i x i r o f c i n c h o n i n e an d v al e r i
q
El i x i r o f c i n c h o n id i n e, u i n i n e, an ate o f am m o n i u m
am m o n v al e r i an at e, i ro n p El i x i r o f c i tro l ac tate o f i r o n
-
.
y
ro h o s p h at e an d s t ryc h n i n e
p El i x i r o f c i tr ate o f am m o n i u m
q
El i x i r o f c i n c h o n i d i n e, u i n i n e, an d b i s m u t h

am m o n . v al er i an ate an d El i x i r o f c i t r ate o f am m on i u m ,
st r y c h n i n e i r o n c h l o r i d e an d w i l d c h er
q
El i x i r o f c i n c h o n i d i n e , u i n i n e
an d i r o n p y ro p h o sp h at e . El i x i r o f c i tr at e o f c affei n e
El i x i r o f c i n c h o n i d i n e an d q u i El i x i r o f c i t rate o f i ro n
n i n e p h o sp h ate . El i x i r o f c i t rate o f i ro n an d
El i x i r of c i n c h o n i di n e an d b ee f
str yc h n i n e El i x i r o f c i trate o f i r o n , cal i
El i x i r o f ci n ch o n i n e . sa a an d
y b ee f
El i x i r o f c i n c h o n i n e , amm o n . El i x i r o f c i tr ate o f i r o n , c al i
v al e r i a n a t e , i r o n py r o p h o s sa a, b eef an d s t r y c h n i n e
y
p h a t e an d s t r yc h n i n e . El i x i r o f c i t r at e o f i ro n , co l u m
El i x i r o f c i n c h o n i n e, am m o n . b o an d r h u b ar b
v al e r i an at e an d q u i n i ne . El i x i r o f c i t r ate o f i r o n , q u i
El i x i r o f c i n c h o n i n e, am m o n . n i n e an d s t ryc h n i n e

v al e r i an at e an d s t r y c h n i n e . El i x i r o f c i t rate o f i r o n p r o t o x
El i x i r o f c i n c h o n i n e , c i n c h o n i ide
d i n e, am m o n v al er i an ate
. . El i x i r o f c i tr ate o f i ro n p ro to x
an d s t r yc h n i n e i d e an d s t rych n i n e
El i x i r o f c i n c h o n i n e an d c i n El i x i r o f c i t ra te an d l ac t at e o f
ch o n i d i n e h o s h at e
p p .

El i x i r o f c i n c h o n i n e, c i n c h o n Eli x i r o f c i tr ate o f l i th i u m
i d i ne an d q u i ni ne
p h os El i x i r o f c i t rate o f p r o to x id e
h ate o f i ro n an d c i n c h o n a
p .

El i x i r o f c i n c h o n i n e , c i n ch o n El i x i r o f c i t r at e o f p ro to x i d e
i d i n e an d s t r yc h n i n e p h o s of i ro n and q u i n i n e p h o s
p h a t e p h ate
 IND EX .
77

El i x i r o f c i trate o f p d
r o to x ie of El i x i r of g e n ti an , c al i sa a an d
y
q
i ro n , u i n i n e an d s tyc h n i n e . n on

El i x i r, Gl and er s El i x i r of i c h l o ri d e of
’
g e n t an ,

El i x i rs co n tai n i ng am m o n i o i ro n , amm o n c i t r ate

. an d
c i trate o f b i sm u t h cal i saya

El i x i rs co n tai n i n g b i s m u t h . El i x i r o f gen ti an , i ro n c h l o r id e
El i x i rs co n tai n i n g fl u i d e x t rac ts, an d amm o n c i t r at e
. 1 07
El i x i rs c o n tai n i n g py pro h os El i x i r o f gi n ger , w i l d 0
95 0 0 0 0 0 0 0

El i x i r fo r g e no r rh oea
l
h ate o f n o n 43
p
El i x i rs con tai n i ng st ry ch n i ne . El i x i r o f g l ycyrrh i z i n 96
Eli x i r o f coco El i x i r o f g l y cyr r h i z i n , aro mati c 9 7
El i x i r o f cofl ee an d cal i saya, El i x i r o f g ri n d e l i a
'

9 8
D es l au r i er s
’
El i x i r o f gr i n d el i a ro b u sta 98
Eli x i r of co h osh , b l ac k , co m El i x i r o f g u ai ac u m 99
p o und El i x i r o f g u aran a 98
El i x i r o f co l u m b o El i x i r o f h eal th 9 1 —1 57
El i x i r o f c o l u mb o , i ro n c i trate El i x i r , H el m o n t s 1 00
an d r h u b ar b ” El i x i r o f h el o n i as 1 00
El i x i r o f col u m bo an d r h u El i x i rs, h i sto ry o f 5 92 -

b ar b El i x i r o f h ops 101
El i x i r s, co n ti n u ou s p rec i p i ta El i x i r o f h op s and c h i ret ta 1 02
ti o n i n El i x i r o f h o p s, c om p o u nd 1 02
El i x i r o f co ryd al i s co m p ou n d . El i x i r o f h yd rate o f c h l oral 57
El i x i r o f co to El i x i r o f h yd ro b ro m ate o f q u i
El i x i r of croto n ch l oral h y n 1n e
El i x i r of h yd roc h l o u i n i n e, q
El i x i r of d am i an a . arsen i o u s ac i d an d i r o n c h l o
El i x i r o f d an d el i o n ri de 1 08
El i x i r o f d an d el i o n , c o m p o u n d , El i x i r of h yp o p h osp h i te o f i r o n 1 09
El i x i r o f d and e l i o n an d q u i n i ne Eli x i r, H u fe l an d s ’
1 03
El i x i r d e G ar us El i x i r o f i od i d e o f arsen i c and
El i x i r, d eri v ati o n o f w o rd m ercu ry
El i x i r d e S t H u b er t p ou r l es
. El i x i r o f i od i d e o f i ron and
c h asseu rs q u i ni ne

El i x i r o f d ew b er ry , co m po u n d El i x i r o f i od i d e o f p o tassi u m
El i x i r e s u c co l i q u i r i tre El i x i r o f i od i d e o f so d i u m
El i x i r o f eucal yp t u s El i x i r o f i o d o-b ro m i d e o f c al
El i x i r o f eu c al yp t u s, co m po u n d C i um o o o o o 0 0 0 0 0 0 0 0 0 0

El i x i r of ferro u s c h l o r i d e El i x i r o f i pe cac .

El i x i r o f ferro us c i t rate Eli x i r o f i ro n , am m o n i o-ci tr ate

El i x i r o f fer ro u s c i t ra te an d cal
i saya El i x i r o f i ro n and b ark
El i x i r o f ferr ou s c i t rate , cal i saya El i x i r o f i ro n b ar k an d h i s
an d s trych n i ne m u th
El i x i r o f fer ro us c i t rate an d El i x i r o f i ro n , b ar k an d peps i n ,
s t r yc h n i n e El i x i r o f i ro n , bar k an d s t ryc h
El i x i r o f fer rou s ph os p h ate an d n i ne
q u i n i ne El i x i r o f i ro n , bar k , s tr ych n i ne
El i x i r o f F o w l e r s so l u ti o n
’
an d b i sm u t h
El i x i r o f gen t i an El i x i r o f i ro n , b ee f an d c i n ch o
El i x i r of gen ti an , co m p o u nd t1 a
 1 78 IND EX .

El i x i r of i r o n an d b i sm u th . El i x i r of i r o n c i t rate a nd b eef .

El i x i r of i ron , b i smu t h an d El i x i r o f i ro n c i trate, cal i saya

si n an d bee f
p pe

El i x i r o f i r o n , b r o m i d e o f : El i x i r o f i r o n c i trate , cal i saya,

El i x i r o f i t o n , c al i saya a n d b eef an d st ry c h n i n e
b eef . El i x i r o f i r o n c i t rate, co l u m bo
El i x i r o f i ro n , cal i saya an d b i s an d r h u b ar b 0 0 0 0 0 0 0 0 0 0 0 0 0 .

m u th El i x i r of i ro n , c i t rate o f p ro to x
El i x i r o f i ron , cal i saya an d id e
El i x i r o f i ro n , c i tr ate o f p ro to x
El i x i r o f i ro n , cal i sa a and
y p p e i d e o f, an d c al i saya
b ill . O O O O 0 0 O O 0 0 0 0 0 0 0
El i x i r o f i ro n , c i t rate o f p ro to x
El i x i r of i r on , c al i sa a
y an d i d e o f, an d c i n ch o na
st r y c h n i n e El i x i r o f i ron , ci t rate o f p ro to x
El i x i r o f i ron an d c i nc h o m i d e o f, an d q u i n i ne p h osp h ate
d me El i x i r o f i ro n c i trate, q u i n i ne
El i x i r of i ro n c h l o r i d e, am m o n an d s t ry c h n i n e
c i t rate an d g e n t i an El i x i r o f i ro n, c i tr o-l ac tate of
El i x i r of i ro n c h l o ri d e an d cal i El i x i r o f i ro n , h y po p h osp h i te o f
saya El i x i r o f i ron, i od i d e of, an d
El i x i r o f n o n ch l o r i d e, cal i say a q u i n i ne
an d am mo n . c i t rate El i x i r of i r o n , l ac tate o f
El i x i r of i r on c h l or i d e , cal i El i x i r o f i ron, l actate an d ci t
saya, am m o n . c i t rat e an d r ate o f

g e n t i an . .
El i x i r o f i ro n, l ac tate o f, and
El i x i r o f i ro n c h l o r i d e an d
c i n c h on a El i x i r of i r o n an d p ep si n
El i x i r of ch l o r i d e,
q u m i ne El i x i r of i ro n , p ep si n an d
h yd roch l o r i d e an d arsen i o u s s tr ch n i n e 1 22
y
ac i d El i x i r o f i ro n , p h osp h ate o f 1 1 1
El i x i r of i ron c h l o r i d e an
.

d El i x i r o f i ron p h osp h ate, q u i

w i l d c h er ry n i n e, c i n ch o n i d i n e an d str c h
y
El i x i r o f i r on c h l o r i d e, w i l d n i ne 1 16
ch er ry an d am mo n c i trate . . El i x i r o f i r on , p r o to c h l o ri d e o f
-
1 08
El i x i r o f i ro n, c i n ch o n a an d El i x i r o f i r on , p r o to x i d e o f 1 05
b ee f El i x i r o f i ro n p ro to x i d e, b ark
El i x i r o f i r o n , c i nc h o n a, b eef an d str ych n i n e

an d str y c h n i n e El i x i r o f i ro n p r o tox i d e an d c al
El i x i r of i r on , c i nch o n a an d i saya
b i s m u th El i x i r o f i ro n p r o tox id e, cal i saya
El i x i r o f i r o n , c i n ch o n a an d an d st r y c h n i n e

l ac to-ph o s ph at e o f l i m e El i x i r o f i ro n p ro to x i d e and
El i x i r o f i ro n , c i n ch o na a nd
” o

c i n ch o n a

p pe si n El i x i r o f i ro n p ro to x i d e and
El i x i r o f i r o n , c i n ch o n a arid qu i ni ne

s tr ch n i 11 e
y . . El i x i r o f i r o n p ro to x i d e, q ui
El i x i r o f i 1 o n , c i n c h o na, s t rych n i n e an d s tr c h n i n e
y
n i n e an d b i sm u t h . Eli x i r o f i r o n p y rop h o sp h ate
El i x i r o f i ro n , c inc h o n i d i n e El i x i r o f i r on p y rop h , amm o n . .

an d st ryc h n i n e v al er i an ate, c i n ch o n i di ne an d

El i x i r o f i ro n , c i t rate o f . s t ryc h n i n e
 1 80 I N D EX .

El i x i r o f l ac t0pep t i n 1 24 El i x i r o f parei ra b rav a an d

El i x i r o f l ac t u ca ri u m 1 25 b u ch u
El i x i r, Lav o l l ey s p u rgat i v e El i x i r p ecto ral e
’
.
43
El i x i r, l a x at i v e 125 E l i x i r pe c t o ral e, Ed i n b u rg h
El i x i r o f l i fe 1 0— 1 1 P h arm ( 1 770)
.

El i x i r o f l i fe , b i t ter 1 27 El i x i r pec toral e, K i ng o f D e n

El i x i r o f l i m e, l ac t o-p h o sp h ate 1 2 8 m ar k s ’
. . .

El i x i r o f l i me, l ac to-p h o sph ate, El i x i r p ec to ral e, reg i s D an i tz a

an d c al i saya El i x i r o f p eps i n .

El i x i r o f l i me , l ac to- ph osph ate, El i x i r o f pe psi n an d am m o n i o

an d c i n c h o n a c i t rate o f bi sm u t h .

El i x i r o f l i m e, l ac to-p h osp h ate, El i x i r o f p e psi n an d b i sm u t h

i ro n an d c i n c h o na El i x i r o f p e psi n , b i sm u t h , am
El i x i r o f l i m e, l ac to -p h osph ate, m o n i o -ci t rat e o f, an d s t ryc h
i ro n p y r o p h osp h ate and cal i 11 1 11 e

saya 78 El i x i r of e
p p s i n , b i sm u t h an d
El i x i r o f l i q uo r i ce 1 28 i ro n

El i x i r o f h q u o ri ce, arom at1e 1 29 El i x i r of e

p p si n , b i sm u t h an d
El i x i r o f l i t h i u m , c i t rate o f 1 30 i ro n p y ro p h
El i x i r o f l u p u l i n 131 El i x i r o f p ep si n , b i sm u t h , i ro n
El i x i r o f m ac ro tys 58 py p r o h an d s t r y c h n i n e
.

El i x i r o f m acro tys, co m po u n d , 58 El i x i r o f pepsi n , b i sm u th an d

El i x i r o f m agnesi a and rh u bar b , 1 55
El i x i r o f m ag nesi u m acetate, El i x i r of e
p p si n ,
b i sm u t h an d
an d r h u b ar b 1 55 s tr
yc h n i ne

El i x i r o f m al to-pepsi n 13 1 El i x i r of e
p p s i n , b i sm u t h
El i x i r o f m an d rak e 133 s tr
y c h n i n e an di ron

El i x i r o f m an d rake, co m po u n d 1 3 3 El i x i r o f p e psi n an d c i n c h o n i a .

El i x i r m an i a 16 Eli x i r o f p epsi n ci n ch o n i a an d
El i x i r o f m at i co 13 1 str ch n i a
y
El i x i r o f m at i co , co m po u n d . 13 2 El i x i r o f p e ps i n an d c i n c h o n i
Eli x i r o f m ayap p l e 133 d ia .

El i x i r o f m ayap p l e , co m po u n d 1 3 3 , El i x i r o f p ep si n , c i n ch o n id i a
El i x i r o f m e r c u ry and i o d i d e o f an d st r ych n i a .

arse n i c El i x i r o f p e p si n and i ro n
El i x i r of m ono-b ro m ated ca m El i x i r o f p ep s i n , i ro n an d b ar k ,
p h o r El i x i r o f p e ps i n , i ro n an d cal i
E l i x i r o f m o n o -
b ro m at ed cam saya

p h o r, c o m o u n d
p 55 El i x i r o f p p
e s i n , i ro n an d c i n

El i x i r o f m u sk r oo t , co m p o u n d , 1 63 c h on a

E l i x i r o f m u s k r oo t an d v al e r i El i x i r o f pe p s i n an d i ro n l ac tate
an at e o f am m o n i u m El i x i r o f p e l si 1 an d i ro n p yr o
El i x i r o f m y r r h , c o m po u n d p h o s p h at e

El i x i rs , n u m b er o f El i x i r o f p epsi n , i ron py r o p h .

E l i x i r o f n u x v o m i ca an d cal i s aya

El i x i r o f o p i u m , N e M u n n s El i x i r of pe psi n , i 1 o n an d
’

El i x i r o f o ran ge s tr ch n i ne
y
El i x i r o f pan c reas El i x i r o f p epsi n , i ro n p yr0 p h
Eli x i r Parac el su s a n d s t r yc h n i n e
’

E l i x i r p ar ego r i c u m El i x i r o f p e p s i n and ph osp h at e

El i x i r o f p arei ra b r av a o f c i n c h o n i di ne
 IND E X . 18 1

Eli x i r of e
p p si n , p h os p h ate o f El i x i r p of
h o sp h ate of
q u i f
i i n e

c i n c h o n i d i n e an d s t r yc h n i n e . an d ci nc h o n i ne

El i x i 1 o f p e p s i n an d p h osp h ate El i x i r o f p h o s p h at e o f q
u i n i ne,

of ci n ch o n i ne c i t ra te o f i ro n p r o to x i d e an d

El i x i r o f p e ps i n , p h os p h at e o f str c h n i ne
y
c i n c h o n i ne an d s t ryc h n i n e . q
El i x i r o f p h os p h ate o f u i n i n e
El i x i r o f p e ps i n an d p h os p h ate a n d i r o n p ro to x i d e, c i t r ate o f .

of q u i ni ne q
El i x i r o f p h o sp h ate o f u i n i n e
El i x i r o f p ep s i n , p h os p h at e o f an d p e p s i n

q u i n i n e an d b i s m u t h q
Eh x i r of p h os p h ate o f u i n i n e
El i x i r o f p ep s m , p h o s p h a te o f p p
e s m a n d b i sm u th

q u i n i n e an d s t r yc h n i n e q
El i x i r o f p h osp h ate o f u i n i n e
El i x i r o f p ep s i n an d p tel ea e psi n an d s t ryc h n i n e
p
El i x i r o f p ep si n an d u i n i aq q
Eh x i r o f p h os p h ate o f u i n i ne
El i x i r o f pep si n , q
u i n i n e an d an d st r yc h n i n e

st r yc h n i n e q
El i x i r o f p h osp h ate o f u i n i n e,
q
El i x i r o f pe psi n , u i ni ne , stryc h st r y c lm i n e an d bi sm u t h

n i n e an d b i s m u t h Eh x i r o f p h o sp h o r u s
El i x i r o f p e p s i n an d w afe r ash . El i x i r o f p h osp h o r u s, co m

E l i x i r o f p e p to n e p o un d

El i xi rs, pe rmanen t . El i x i r o f p h o sp h o ro u s, q
u i n i ne

El i x i r o f p h o s p h at e o f c i n ch o n an d s t ryc h n i n e
El i x i r o f p od o p h yl l u m
El i x i r of p h o s h ate o f c i n c h o n
p El i x i r o f p o tass i u m ace tate
i d i n e, c i nc h o n i n e an d s t ry c h El i x i r o f p o tassi u m ace tate an d
m ne
El i x i r o f p h o sp h at e o f c i n c h o n El i x i r o f p o tass i u m ac e tate,
i d i n e an d p e p s i n . 142 b u c h u an d j u n i p e r 1 48
El i x i r o f p h o s p h ate o f c i n c h o n El i x i r o f p o tass i u m arsen i te 1 48
i d i n e, p e p si n an d s tr y ch n i n e . 142 El i x i r o f p o tassi u m b r o m i d u m . 1 48
El i x i r o f p h osp h ate o f c i n c h o El i x i r o f p o tass i u m i o d i d e I 49
n i n e an d c i n c h o n id i n e 80 El i x i r p ro b l e m , fo r p h arma
Eli x i r o f ph o sp h ate o f c i n c h o C 1 s ts 26
n i n e an d p ep s i n . 1 43 El i x i r p r o p r i e t at i s 1 2 , 1 3 , 1 5, 1 49
E l i x i r o f p h o s p h at e o f c i n c h o El i x i r p ro p r i e tat i s c u m ac id o 1 3 -
1 50
n i n e , p e p s i n an d s t ryc h n i n e x4 3 El i x i r p r o p r i e tat i s w i t h d i s
El i x i r o f p h os p h ate o f c i n c h o t i l l ed v i n eg ar 13 -
1 50
n i n e an d s t r yc h n i n e 80 El i x i r o f p r o to c h l o r i d e o f i ro n
-
. 1 08
El i x i r o f p h o s p h ate o f i ro n 1 1 1 El i x i r o f p ro to x i d e o f i ro n 1 05
El i x i r o f p h o sp h ate o f i ro n an d E l i x i r o f p r o to x i d e o f i ro n , b ark
an d s t ry c h n i n e
El i x i r of h os h a t e o f i El i x i r o f p r o to x i d e o f i r o n an d
p p ro n ,

q ui n i ne , c i n c h o n id i n e an d cal i saya
s t ryc h n i n e 1 16 El i x i r o f p r o t o x i d e o f i r o n c al
El i x i r o f p h o s p h ate o f i ro n i saya an d s t ryc h n i n e
q u i n i n e an d s t r yc h n i n e I I2 El i x i r o f p r o to x i d e o f i ro n an d
El i x i r o f p h o s p h at e o f q u i n i n e . ci nch o n a

El i x i r o f p h o s p h a t e o f q u i n i n e El i x i r o f p ro to x i d e o f i ro n an d
an d c i n c h o n i d i n e
El i xi r o f p h o s p h at e o f q u i n i n e, El i x i r o f p r o t o x id e o f i r o n , q u i
c i n c h o n i d i n e an d c i n c h o n i n e . 85 n i n e an d s tr c h n i n e
.
y
1 82 I ND E X .

El i x i r o f p tel ea and pepsi n . 1 44 El i x i r of

py p
r o h os p h ate o f i ro n ,
El i x i r , p u rg at i v e , Lav o l l ey s
’
43 q u i n i n e, amm o n . v al e r . an d
El i x i r , p u rg at i v e , Le ro y s 1 26
’
s tr
yc h
E l i x i r o f p y ro p h osp h ate o f i ro n 1 1 4 El i x i r o f p e p h o s p h ate o f i ro n
El i x i r o f pyro p h o s p h ate o f i ro n q u i n i n e an d c i n c h o n i d i n e

an d b i s m u t h am m o n i o c i t rat e
-
49 El i x i r o f pyro p h os ph ate o f n o n ,
El i x i r o f p yr o p h osp h ate o f i ro n q u i n i ne , c i n ch o n i ne an d
bi s m u t h an d pe ps i n s t r y ch

El i x i r o f p y ro p h o sp h ate o f i ro n El 1 x 1 r o f p y ro p h o sp h a te o f i r o n
an d c al i s aya 1 6 , 76 q u i n i n e an d s t r c h
y
El i x i r o f pyro p h os ph ate o f i ro n , El i x i r o f pyro p h osp h ate o f i ro n
c al i s aya an d amm o n . c i t rate q u i n i n e v al e r an d s t r c h
y
.

o f bi s m u t h El i x i r o f pyro p h osp h ate o f i ro n

El i x i r o f pyro p h o sp h ate o f i ro n , an d s t r yc h
c al i saya, b i sm u t h an d s t ryc h El i x i r o f py r0p l1 osp h ate o f i ro n
ni ne a n d am m o n v a l e r .

El i x i r o f p yr o p h os p h ate o f i ro n , El i x i r o f py ro p h osp h ate o f i ro n ,

c al i sa a an d p e s i n
y p v al e r am m o n ,
. u i n i n e, c i n
. q
El i x i r o f p yro p h o sp h at e o f i ro n c h o n i d i n e an d s t r c h
y
c al i s aya an d s tryc h n i n e 1 6, 79 q
El i x i r o f u i n i ne
El i x i r o f p e p h o sp h ate o f i ron q
El i x i r o f u i n i ne , amm o n v al e r . .

an d c i n c h o n a an d c i n c h o n i d i n e
El i x i r o f p y ro p h osp h at e o f i ron El i x i r of q
u i n i n e, am m o n .

c i n c h o n a an d p e p si n v al e r , c i n c h on i d i n e, ro
.
py
El i x i r o f py ro p h osp h ate o f i ro n p h o s h ate o f i ro n an d s t r c h
p y .

an d c i n c h o n id i n e El i x i r o f q
u i n i n e, amm o n .

Eh x i r o f pyro p h o sp h ate o f i r o n , v al er , . c i n c h on i d i n e an d
c i n c h o n i d i n e , am mo n v al er
. . s t r yc h 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

an d s t r y ch El i x i r of q u i n i n e, am mo n v al e r . .

El i x i r o f p yro ph osp h ate o f i ro n an d c i n c h o n i d i n e

c i n c h o n i d i n e an d s t rych El i x i r o f q u i n i n e, amm o n .

El i x i r o f p yro p h o sp h ate o f i ro n , v al er , c i n c h o n i n e an d s t r c h
.
y .

c i n c h o n i d i n e an d v al e r am . El i x i r o f q u i ni ne, amm o n v al e r . .

mon and p y1 0 p h o s p h at e o f i r o n .

El i x i 1 o f pyro ph osph at e o f i ro n El i x i r o f q u i n i n e , amm o n .

an d ci n c h o n i n e v al e r , r o h o s h ate o f i r on
py p
.
p
El i x i r o f p e p h osp h ate of n o n , an d s t r yc h
c i n c h o n i n e an d am m o n v al e r . .
35 El i x i r o f q u i n i n e , a m m o n v al e r . .

El i x i r o f p e p h o sp h ate o f i r o n , an d s t ryc h

c i n c h o n i ne , am m o n v al e r
. . El i x i r o f q u i n i ne, b i s m u th an d
an d st r ch e si n
y p p .

El i x i r o f p yro p h osp h ate o f i r o n El i x i r o f q u i n i n e, bi s u l p h

an d p e p s i n El i x i r o f q u i n i ne, b ro m id e o f
El i x i r o f p y ro ph osph at e o f i r o n El i x i r o f q u i n i n e an d c i n ch o n
e s i n , b i sm an d s t r yc h i d ine h os p h ate
q
p p . 0 0 0 0 0 0 0

E l i x i r o f p yro p h o s p h ate o f i r o n El i x i r o u i n i n e , ci n ch o n i d in e

e s i n an d s t r c h
y an d c i n c h o n i n e p h o s h at e
p p p
El i x i r o f p yro p h o sp h ate o f i r o n El i x i r o f q u i n i n e , c i n c h o n i d i n e
an d q u i n i ne an d i r o n p yro p h o s h at e
p
El i \ i r o f p e p h os p h at e o f i r o n El i x i r o f q u i n i n e an d c i n c h o n
q u i n i n e an d amm o n . v al e r i n c p h o sp h ate
1 84 IND E X .

El i x i r o f so d i u m i od id e 1 60 El i x i r of st ry ch . , c i n c h o n i n e,

El i x i r sq u i re s
’
. . 1 60 q u i n i ne an d v al e r . am m o n
40
El i x i r o f s t i l l i ng i a 16 1 El i x i r o f s t ry c h . an d c i t rate o f

El i x i r o f s t i l l i n g i a. co m o u n d 161 i ro n p ro to x
p
El i x i r s to m ac h i c u m 1 5—1 62 El i x i r o f st ryc h and fe r ro us
.

El i x i r o f s t r yc h , am m o n v al er
. . . c i t rate

an d c i nc h o n i ne El i x i r o f st ryc h an d i ro n
. .

El i x i r o f s t ryc h , b ark an d b i s
. El i x i r of s t ryc h i r o n , b ar k
m u th , fe r r ated . an d bi sm u t h

El i x i r o f s tr yc h , b ar k an d . El i x i r o f s t ryc h i r o n and c i n
.

i ro n 77 79
- c h o n a
El i x i r o f st ryc h , b ee f, c i trate
. El i x i r o f s tr yc h , i r o n , c i n .

o f i ro n an d c al i saya c h o na an d bi sm u th .

El i x i r o f s t rych , b ee f, i ro n an d
. El i x i r o f s t ryc h , i ro n an d c i n .

c i n ch o n a c h o n i d i ne

El i x i r o f st rych an d b i sm u th . El i x i r o f st rych , i ro n an d p ep .

am m o n i o -
c i t r ate s 111 .

El i x i r o f st rych , b i sm u th , i ro n
. El i x i r o f st ryc h , i r o n p ro t o x . .

o p h os p h ate an d i n a n d b a k
py r p p
e s r

El i x i r o f s t ryc h , b i sm u th , pe p
. El i x i r o f s t ryc h i r o n p r o to x. .

si n an d i ro n an d c al i saya

El i x i r o f strych , cal i saya an d . El i x i r o f st ryc h , i ro n p r o to x .

fer ro u s ci trate
. i d e an d q u i n i n e
El i x i r o f str ych , cal i saya and . El i x i r o f stryc h , i r on p h os .

i ro n p h a t e , c i n c h o n i d i n e an d q ui
El i x i r o f s tryc h , c i n ch o n i a, . 11 1 ne

i ro n an d q u i n i a El i x i r o f s t ryc h an d i r o n py r o .

El i x i r o f s t rych n i a, c i n ch on i a p h o s p h a t e

an d p e p s i n Eli x i r o f s t ryc h i ro n p y r o
El i x i r o f s trych n i a, c i n ch o n i d i a p h o s h ate
p b i s m u t h an d c al i

an d p e p si n . saya

El i x i r o f s trych n i ne an d c i n El i x i r o f s t ryc h., i ro n p ) r o

c h on i d i n e p h o s p h a t e a n d c a l i s a a
y
El i x i r o f s t ry ch , c i n c h o n id i ne
. El i x i r o f s t ryc h , i ro n p y ro .

an d i ro n p yr o ph osph ate p h o s h ate, c i n c h o n i d i n e an d

p
El i x i r o f s tr yc h n i n e , c i n ch o n i amm o n v al e r .

d i ne p h o s p h ate an d p e p s i n El i x i r o f s t r yc h , i ro n p y ro
. .

El i x i r o f s t rych , c i n ch o n i d i ne ,
.
p h o s p h a t e , c i n c h o n i n e a n d
q u i n i ne an d am mo n v al er 3 8 a m . m . o n v al e r .

El i x i r o f str yc h , c i n ch o n i n e ,
. El i x i r o f s t ry c h , i ro n pyro .

ci n c h o n i d i ne a nd am mo n p h o s
.
p h a t e a n d e
p p s i n
v al e r El i x i r o f st ryc h , i ro n py r o .

El i x i r o f s t ryc h , c i n c h on i n e h o s h ate , q u i n i n e an d am
.
p p
an d c i n ch o n i d i n e p h o s p h at es 82 m o n v al er
. .

El i x i r o f s t r yc h and c i nc ho n. El i x i r o f s t ryc h , i ro n p y ro .

i n e p h o sp h ate p h o s p h a t e an d q u i n i n e v al er . [2 0
E l i x i r o f s t r yc h , c i n c h o n i n e . El i x i r o f s t ry c h , i ro n p yro .

p h os p h a t e an d p e psi n p. h os p h a t e , v al e r a m m o n , . .

El i x i r o f st ryc h , c i n c h o n i n e ,
. q u i n i n e an d c i n ch on id i n e
q u i n i n e an d i ro n p yr0 p h os El i x i r o f s trych , i ro n an d q u i .

p h ate n i ne
 IND EX . 185

El i x i r o f s t1
y c h .
, i ro n , q u i n i ne El i x i r of v al er . am m o n . , ci n

an d c i n c h o n id i n e c h o n id i n e an d i ro n p yro p h o s
El i x i r of s tr
y ch. , i ron ai id p h a t e

l
v a er . q
u i n i ne El i x i r o f v al e r am m o n , c i n
. .

El i x i r o f s t rych , p e psi n an d c h o n i d i ne, i ro n o h os

.
py pr

b i s m u t h a m m o n i o -c i t rate p h a t e a n d s tr c h
y
El i x i r o f s t r y c h n i n e p h o s p h o r u s El i x i r o f v al e r am m o n an d . .

an d u i n i ne c i n ch o n i ne
q .

El i x i r o f st ry c h n i n e an d u i n i ne q . El i x i r o f v al er am m o n , ci n
. .

E l i x i r o f s t ry c h , u i n i n e an d
. q c h o n i n e an d i ro n
py pro h os

am m o n .v al er
p h at e

E l i x i r o f s t r yc h , u i n i n e and
. q El i x i r o f v al e r am m o n , c i n
. .

i ro n c i t r a t e . c h o n i n e, i r o n p y r o p h osp h ate

El i x i r o f s t rych n i n e, uini ne q an d s tryc h

an d i ro n p h o sp l1 a te . . El i x i r o f v al er am m o n , c i n
. .

El i x i r o f s tr yc h , u i n i n e an d
. q c h o n i n e a nd st r ych

i r o n p y ro p h osp h ate El i x i r o f v al er amm o n an d . .

El i x i r o f s t rych , u i n i n e an d
. q i ro n p e p h osp h ate
El i x i r o f v al er amm o n an d. .

El i x i r of s t rych n i n e, q u i n i n e, m u sk roo t
p p
e si n an d b i sm u t h . El i x i r o f v al er amm o n an d . .

El i x i r o f s trych an d .u i n i ne q
p h o s h at e
p El i x i r o f v al er am mo n , q u i
. .

El i x i r o f s t ry ch , u i n i ne p h os
. q n i n e an d c i n ch o n i d i n e

p h at e an d b i s m u th El i x i r o f v al er ammo n , q u i
. .

El i x i r o f s t r y ch , u i n i ne p h o s
. q n i n e, c i n c h o n i d i n e , i r o n
py ro

p h a t e a n d p pe si n .
p h o s h ate an d s tr ch
p y
El i x i r o f s t r yc h an d .u i n i ne q El i x i r o f v al e r am m on , q u i
. .

v al e r n i n e , c i n ch o n i d i n e an d s t r yc h .

El i x i r o f s tr yc h n i n e v al er
°
. El i x i r o f v al er amm o n , q u i
. .

El i x i r o f s trych an d v al er
. n i n e an d c i n c h o n i n e
i an at e o f amm o n i u m . El i x i r o f v al e r am mon , q u i
. .

El i x i r o f su m b u l , com p oi1 n d . n i n e, c i n c h o n i n e an d s t r yc h .

El i x i r o f su m b u l and v al e r El i x i r o f v al er am m o n , q u i
. .

i an at e o f am m o n i u m n i n e an d i ro n p y ro p h osp h at e .

El i x i r o f s u l p h ate o f u i n i n e q . El i x i r o f v al er am m o n , q u i
. .

El i x i r o f t ar n i n e, i r o n o h o s h ate an d
py pr p
El i x i r o f ta r , co m p o u n d s t r yc h

El i x i r o f ta r ax ac u m El i x i r o f v al e r amm o n , q u i
. .

El i x i r o f tar ax ac u m , co m p o u n d . n i n e an d s t ry ch

j
El i x i r o f t h u a o cc i d e n t al i s El i x i r o f v al e r amm o n an d . .

El i x i r u te r i n u m st r
y ch .

El i x i r o f v al e r i an . El i x i r f v al e r am m on an d
o . .

Eli x i r o f v al e r i an ate o f am m o n . s umb u l

El i x i r o f v al er a mm o n an d c i n
. . El i x i r o f v al er ui ni ne
. q .

c h on i d i n e El i x i r o f v al e r u i n i n e,
. q
i ro n
El i x i r o f v a l e r am m o n . cin .
, an d s t r yc h
ch on i d i ne an d c i nc h o n i ne .
E l i x i r o f v al e r u i n i n e,
. q
i ro n
El i x i r o f v al e r a m m o n . cin .
,
r
i ro
y p h o s h at e an d st r c h
p y
c h o n i d i n e, c i nch o n i n e an d Eh x i r o f v al e r u i ni ne. q
an d

st r y ch
1 86 I ND E X .

El i x i r v al e r i an ate o f s t r
y c h H an co c k , M r J F , an d el i x i rs 1 9
n i n e . 1 63 . . .

El i x i r o f v al e r i an at e o f z i n c 1 6 9 H e al t h e l i x i r
.
—
9 1 57
1
El i x i r v i sc e r al e H o fi m an m 10 1 H el mo n t 12
El i x i r o f v i sce ral e K l e i n i i H e l m o n t s el i x 1 r 1 4—
’
1 24 1 00
1—
0 0 0 0 0 0 0 0 0 0 0

El i x i r v i tae 10 H i s to r y o f e l i x i rs 23
El i x i r o f v i tri o l H o fl m an n s an od y n e
'
’
1 66 1 67
El i x i r o f v i t r i o l d u l ce —
1 6 2 1 6 7 H o fl m an n s s to m ach e l i x i r
’
'

101
El i x i r o f v i t r i o l s w ee t —
1 62 1 6 7 H o e fl an d s el i x i r
’
1 03
El i x i r o f v i t r i o l , M yn fi c h t s 1 66 H u n ter s el i x i r , S t H u b er t s
’ ’
1 61 .

El i x i r of v i tri o l v o l at i le, Vi
g au Ps 1 67 I saac H ol l an d e s 12
El i x i r v om i to-p u rg at i v e, Le ro y s 1 26 I ro n pyro p h o sp h ate i n
’
.
e l i x i rs . 1 13
Q

El i x i r v s co rd i al
. 16
El i x i r o f w afe r ash an d p ep si n . 1 44 J al ap , co m p o un d t i n c tu re of. 43
El i x i r o f Wah oo 1 68
El i x i r, w h i te 1 58 K i n g o f D en mar k s p e c t o ral e ’

El i x i r o f w i l d ch e r ry 56 el i x i r

El i x i r o f w i l d c h e r ry, c i t rate o f K l e i n s sto m ac h e l i x i r

’

am m o n an d i ro n c h l o r i d e
. .
57
El i x i r o f w i ld c h e rry, ferrated .
57 Lax at i v e el i x i r 1 25
El i x i r o f w i ld c h e r ry an d i ro n Lem ery 12
c h l or i d e Le ro y s p u rgat i v e el i x i r
’
1 26
El i f w i ld c h e r r y, i ro n c h l o r Ler oy s v o m i to p u rgat i v e el i x i r . 1 26
’
xi r o -

i d e an d am m o n c i t rate Le ttso m s e l i x i r
’
. 1 27
El i x i r o f w i ld g i n ger Li fe el i x i r , bi t ter 127
El i x i r o f m m , v al eri an ate
M an i a t h e el i x i r
,

F er rated el i x i r o f b ar k 79 M c M u n n s e l i x i r of op i um
’

F e r rated e l i x i r o f b ar k an d h i s M o u n tai n w i ne
m u th 77 M y n fi c h t s e l i x i r
’

F er rated el i x i r o f b ar k , b i s M y n fi c h t s e l i x i r o f v i tr i o l
’

m u th an d s t ryc lm i n e
F er rated e l i x i r of b ark an d b i s N ew ar k Ph ar m ac e u ti cal Asso
m u th . 49 c i ati o n an d e l i x i rs

F er rated e l i x i r o f b ar k an d cal
i saya 76 O i l o f o r a n g e 1 36
F err ated el i x i r o f b ar k an d p e p O i l y sp i ri t, v o l ati l e 99
1 20 O p i u m , c am p h o r ated t i n c t u re . 15
F e rr ated e l i x i r o f b ar k an d
w i l d c h e r ry Paracel su s
F i xed al k al i n e sal t Parac el s u s, el i x i r
F l u i d e x t r ac ts i n p rep arati o n o f Parego r i c
el i x i r s Pec to ral e e l i x i r
F ri ar Baco n Pec to r al e e l i x i r o f Ed i n b u rgh
Ph arm , 1 770 .

G ar d n er , Mr R W , and
. . . Perm an en t el i x i rs
el i x i rs . Pe p si n sacc h arated
G ar u s el i x i r
’
P h ar m ac eu ti c al A ssoc i at i o n ,
G en t i an , co m po u n d t i n c t u re o f . A m eri c an , an d el i x i rs 1 8—21
Ph ar m ac eu ti c al Assoc i at i on o f
H el l e r ’
s ac id el i x i r 99 N e w ark , and el i x i rs 0 0 0 0 0 0 0 0 0
 CHEMISTRY OF MEDICINES
A TE X T AND R E F E R E N C E BO O K
FO R T H E U S E O F

MEDICAL STUDENTS ,
PHYSICIANS AND PHARMACISTS .

By 1 . U . LLO YD ,

CI NC NN T I A I, 0 11 1 0 .

P ri ce : Cl ot/z ,
S /z eep $3 , 25 .

RO B ERT C LAR K E Co .
,
P u bli sh e r s , C i n ci n n at i , 0 .

F 0 U R T H ED I T / 01 V .

T h i s w o r k i s i n te n d ed as a te x t an d co n v en i en t r efere n c e b o ok fo r
s t u d en ts , an d al so fo r p h ys i c i an s an d p h ar m ac i s ts I t o p en s w i th a c h ap .

te r o n ap p ar at u s , g i v i n g d esc r i p t i o n s an d d i rec t i o n s fo r t h e i r u se, fo l l o w ed

b y a c h ap ter 0 11 c h em i c al t h eo ry ; c o n tai n i ng a l so e x p l an at i o n s o f p h ysi
c a l p h e n o m e n a an d c o n d i t i o n s ( e l e c t r i c i ty , m ag n et i sm , c r ys ta l l o g r a h ,
p y
an d o f v ar i o u s p r o cesses, l i k e ev ap o r at i o n , fi l t e r i n g , d i al ys i s , e tc .

T h en fo l l o w s i n o rg an i c c h em i s t r y, d i v i d ed , as u su al , i n to c h e m i s t r y o f
n o n m et al l i c a n d o f m e tal l i c e l e m en ts , ar r an g e d i n to g r o u p s
-
T h e ac i d s .

ar e al l c o n s i d er ed u n d e r h yd r o g e n , as co m p o u n d s o f t h at e l em en t , an d i n
al p h ab e t i cal o rd er ; t h e l at te r ar r an g e m e n t b ei n g al so u sed u n d e r t h e
h e ad s o f t h e m e tal s fo r t h e i r s al ts .

I n t h e c h ap te r 0 11 o rg an i c c h e m i s tr y , t h e c om p o u n d s ar e c on si d e red as
h yd r o car b o n s , al c o h o l s, e t h e rs, ald e h yd s, c ar b o h yd rates , am i n es , al k a
l o id s g l u c os i d es , r es i n s o l eo res i n s , an d v o l a t i l e o i l s
, , T h e l as t fe w p ages .

c o n tai n d i rec t i o n s fo r th e e x am i n at i o n o f u r i n e .

A l l t h e i m p o r tan t e l em e n ts are d esc r i b e d , b u t o f th e c o m p o u n d s t h ose

w h i c h h av e b e en e m p l o ye d i n m ed i c i n es are t reated o f, al m o s t to t h e e x
e l u s i o n o f o t h er s, a fe w i m p o r t an t o n es e x c e p ted T h e l i m i t s t h u s d r aw n .

b y t h e au t h o r h av e e n ab l e d h i m t o g i v e, i n t h e s p ac e at h an d , o u t l i n e s o f
t h e p ro c esses , w i th m an y u se fu l , p r ac ti c al h i n ts , d esc r i p t i o n s o f t h e v a r i
o us co m p o u n d s, an d b r i e f d i r ec t i o n s fo r d e te rm i n i n g t h e i r p u r i ty .

— A m e r i ca n j ou r n a l of l rmae
y P h i l a d elp h i a ,
.

Li k e al l t h e w o r k yo u d o ; i t i s h i g h l y c r ed i tab l e .

R o B E R T s B A R I H O LO W M D , j efi e r s r m fif ed i c a l Col l eg e
‘ ' ‘ '
, . . .

I tak e g r e at p l eas u r e i n re c o m m e n d i ng y o u r w o r k o n t h e C h em i s
t r y o f M edi c i n es t o a l l m e d i c al s t u d e n ts F o r cl ear n ess , co m p l et en ess
’
.

an d c o n c i sen ess, i t h as n o s u p er i o r
”
.

M . DL Y
W L D U E P r of Ch enn s try {Mi a m i M ed i ca l Col l eg e C i n 0
,
.
'

, , .
, .
 I t w as to b e ex p ec te d th at a ge n t l e man e n gaged fo r m an y years i n
t h e m an u fac t u re, an d , at t h e sam e t i m e, i n t eac h i n g c h em i s t ry to a cl ass
o f m ed i c al s t u d en t s, w o u l d b e ab l e, fr o m t h e k n o w l ed g e t h us o b tai n ed o f
q
w h at i s r e u i si te fo r a me d i cal c l ass, to p re se n t th e c an d i d ate s fo r o u r p ro
fessi o n a tex t-b ook o f u n u su al v al u e Th e v ol ume befo re u s fu l l y us ti . j
”
fi es t h i s e x c tat i o n .

JA S CME Y N D M A N M D , P r o/ Z M ed i ca l C h em i s t ry , ri l ed i ca l Col l eg e o
.
, . .
f Oh i o .

I ts pl an i s n o v el an d goo d I ts th o ro u gh l y p rac ti cal c h arac te r w i l l

.

mak e i t par ti cu l arl y v al u ab l e to al l w h o st ud y c h em i st ry as app l i ed to

m ed i c i n es an d t h e ar ts Y o u r b o o k w i l l b e a v al uabl e ass i s tan t to th ose
.

e ngaged i n teach i n g c h em i s t r y t o m ed i c al an d h ar m ac e u t i cal s tu d en ts ”

.

N . W . LO RD , Ch em i s t i n c h a rg e o f Oh i o ta t : L a bo r a to ry , Col u m bu s .

I feel c on fid en t t h at i t w i l l p ro ve v a u ab l e
l to st u d en ts , an d sh al l n o t

fai l to reco m men d i t .

C H AS . O C U RT M A N , Ch e m i s t Col l eg e
. o f P h a r m a cy , S t Lo u i s .

I l i k e th e m eth o d an d g e n e r al ar r an
g em en t of th e w o r k .

J W . . HO LL ND
A ,
P r o/ i Ch em i s t ry , U n i r'er s i ty f
o L ou i s v i l l e .

O n e o f th e b est feat u res o f th e b oo k i s ab u nd an ce o f p rac ti cal d e tai l s,

w h i c h i s t h e o u tco me o f th e au th o r s l arg e m an u fac t u ri ng e x p er i en c e W e
’
.

k n o w o f n o o n e b etter cal c u l ated to i m p ar t such i n fo r m ati on th an M r .

Ll o yd , w h o i s th e p rac ti cal m an ag er o f on e o f th e b est eq u i pp ed l ab o ra

t or i es i n t h e W es t
—Th e M on th ly Rev i ew of M ed i ci n e a n d P ha r m a cy P h i l a d elp h i a
.

, .

We co n si d er th e b ook as th e b est p rac t i cal w or k o n m ed i cal ch e m i stry

t h at c an b e fo u n d i n th e m ar k et b y t h e st u d en t, th e p h ysi c i an , o r d r ug
g i st . —S t . Lou i s Cl i n i ca l Reco r d .

We c an reco m m en d th e b oo k as a v ery p rac t i cal an d easi l y i n tel l i gi bl e

g u id e fo r i n t ro d u c t i on t o th e s t u d y o f c h em i stry, an d p ar t i c u l ar l y so to
st u d en ts o f m ed i c i ne .

T h i s w o rk seem s to b e a n ew d e p ar tu re i n th e w ay O f b o o k s o n ch em
i st r y .Th e w r i ter p l aces th e fac ts b efo re th e read er i n as c l ear an d c on
c i se a w ay as p ossi b l e, b u t n o t s p ar i n g w o r d s w h en n ec ess ary to i n s u re a

c l ear an d co m p l ete u n d e rs tan d i n g o f t h e su b ec t I n fac t, i t m i g h t b e sai d j .

t o tak e th e p l ace of a p r i v ate i n s t r u c tor i n ch em i st ry T h e w r i te r i m .

v es u o n o th er w o r k s, i a t h at o f m en ti o n i n h i i l i m
p ro p g t e p r n c p a p r i ti es
u

o r ad u l ter at i o n s t h at m ay b e fo u n d i n c h em i cal s, an d i n i v in
g g p per
ro

t es ts fo r t h ei r d e t ec t i on T h i s, i f d o n e w i t h c ar e, i s a v al u ab l e ad d i t i on ,
.

an d t o al l w h o k now t h e w r i te r , h i s r e p u tat i o n i s su ffi c i e n t g u ar an tee

— Th e
. .

P h a r ma ci s t and Ch em i s t , Ch i cag o .

T h e au th or w astes b u t l i t tl e t i m e o n th eory, b u t g i v es c l ear d esc r i p

t i on s o f t h e p r ocesses b y w h i c h ch em i cal s are p rep ar ed , m e n t i o n s t h e
r i n ci p al i m p uri ti es or ad u l ter at i o n s to w h i c h t h ey are l i ab l e , an d s u
p p p l i es
t es t s for th ei r d etec ti on Po i so n s an d th ei r an t i d o tes are a l s o s p ec i fi e d i n
.

t h ei r p ro p er p l ace T h e syn o n ym s o f such c om p o u n d s as h av e an y are

.

n o t fo rgo t ten , n o r are t h e ato m i c w e i g h ts, s p ec i fi c g rav i t i es , so l u bi l i ti es,

et c , o f each su b s tan ce as far as k n o w n

. I n th i s w ay t h e c h e m i c al h i sto ry .

o f th e el e men ts o r co m p o u n d s i s co m p l eted i n a v e ry c l ear an d s u c c i n c t

m an n er Th e b oo k i s p r i n te d i n go o d r ead abl e typ e, an d i l l us t r ated w i th

.

w oo d c u ts i n th e te x t I t w i l l p ro v e a v al u ab l e ad d i ti o n t o th e l i b r ar y ,
.

usefu l fo r al l , an d al mo st i n d i spe n sab l e to th e st u d e n t i n m ed i c i n e o r h a r

p
mac y . —Th e D r ug g i st
’
s Ci r cu l a r a nd Ch em i ca l Ga z ette, N Y. .
2 Robert Clarke ( 1: Co P u bli cati ons
’
. 8 .

t h e Cor resp on d en ce b e t w een Geor ge W ash i n gton an d W i l l i am

C r aw fo rd , co n cer n i n g W e st er n La n d s SW ) 1 00 . .

B U TT ERF I ELD ( C W ) T h e D i scov ery o f t h e N or th w est i n 16 3 4

. .
,

by J o h n N i c ol e t , w i th a S k e tc h of h i s Li fe l 2m o 1 00 . .

CLAR K ( Col Geo r g e Ro ge rs ) . S k e tch es of h i s Cam p ai gn i n th e .

I l i n o i s i n 1 778—
l 9 W i th an I n t r o du c ti o n b y H o n H e n ry . .

P i r t l e, an d an A p p e n d i x 8v o $ 2 00 Large p ap e r, 4 00 . . .

C O FF I N ( Lev i ) Th e Re m i n i sc en ces o f Lev i Coffi n t h e Rep u t e d

.
,

P r es i d e n t o f t h e U n d e rg r o u n d Rai l ro ad A B i i e f H i st o r y o f .

t h e Lab o rs o f a Li fe t i m e m be h al f o f t h e S av e W i t h S to r i e s l .

o f F u gi t i v e S av e s e t c e tc l 2m o l 2 00 ,
.
, . .

C O LL1 ER ( P e t e r ) S o r gh u m : i ts Cu l t u re an d M an u fac tu re Eco

.

n o m i c al l y Co n s i d e r e d a n d as a So u r ce o f S u gar S y ru p an d , ,

F od d e r I l l u s t rated
. 1 2111 0 I n p r ess . . .

CO N S T 1T UT 1 0N O F T H E U N l T En ST AT ES ETC T h e D ec l ar at i o n o f ,
.

I n d ep e n d e n c e J u l y t h e Ar ti c l es O f Co n fed er at i on
, ,

J u l y 9 1 778 ; t h e Co n sti t u t i o n of th e U n i t ed S tates, S ep tem ber

,

t h e Fi fte e n Am e n d m e n t t o t h e Co n s t i t u t i o n , an d
I n d e x ; Wash i ng to n s F ar e w el l A d d ress, S ep tem b er 7, 1 796
’
.

8v o . P ap e r . 25
C O RNWELL ( H G ) Co n s u l t ati o n C h ar t o f t h e Ey e Sy m p t om s
. .
-

a n d Ey e Com p l i c at i o n s o f G en e r al D i sea se
-
14 x 20 i n c h es . .

M o u n ted o n Ro l l e r . 50
CR AI G ( N B ) Th e Ol d e n Ti m e
. . A M o n th l y P u b l i cat i o n d e .
,

v o t ed t o t h e P 1 e s e rv ati o n O f D oc u m e n t s o f Earl y H i st o r y ,

etc . O ri gi n al l y P u bl i s h e d at Pi ttsb u rg, i n 1 8 46 4 7 2 v ol s -

. .

8vo . 1 0 00
D RAK E ( D ) Pi o n ee r Li fe i n K en t u ck y
. Ed i ted w i t h N o t es .
,

a n d a B i ograp h i c al Sk e tch by h i s S o n , H on Ch as D D rak e . . . .

8 vo . $3 00 Lar ge p ap e r . 6 00 .

D U B REU I L ( A ) V i n eyar d Cu l tu re I m p r ov ed an d Ch eap en ed

. .

Ed i te d b y D r J A W ard e r l 2m o . . . 2 00 . .

Gran d m a s Ch r i st m as D ay
’
ELLARD ( V i rgi n i a G ) I ll us
. Sq . . .

l 2m o . 1 00
EV ERTS ( O r p h eu s ) W h at S h al l W e D o W i t h th e D r u n k ard "
.

A Rati o n al V i ew of t h e U se o f B r ai n S ti m u l an ts 8 vo . .

P ap e r . 50
F AM I LY EX P EN S E B O O K A P r i n te d A ccou n t B ook w i th Ap p r o .
,

r i a t e C o l u m n s an d H e ad i n gs fo r k e ep i n g a Com p l e t e Rec o rd
p ,

o f Fam i l y Ex p e n s es l 2m o . 50 .

F i NL EY ( I J ) a n d P U T N AM ( R ) Pi on eer Rec or d an d Rem i n i s

. .

c e n c e s o f t h e Ear l y S e t tl er s a n d S et t l em e n t o f Ross Co u n ty ,

Oh i o . SW ) . 2 50
F LET C H ER ( Wm B M D ) Ch ol er a : i ts Ch arac ter i st i cs H i s to r y
. . .
, .

T reat m e n t e t c 8vo P ap er 1 00
—
. . .

FO RC E ( M F E ss ay s P r e H i s t or i c M a n D ar w i n i sm an d .
-

De y i t — Ih e I ou n d B u i l d ers 8 v o P ap e r
'
. . .

F O RC E ( M F ) S om e Earl y N o t i ce s o f t h e I n d i an s o f O h i o
. . .

TO W h at Race d i d t h e M o u n d B u i l d ers B el on g " 8 v o .

P a per . 50
F REEM AN ( El l en ) M an u al o f t h e F re n ch V erb , t o accom p an y
.
 A LL A G H ER

ot h e r P o em s l 2m o . . 2 00
G RI M E E ( F C o n si d er at i on s o n t h e Nat u re an d Te n d e n c y O f
) .

F r ee I n st i t u t i o n s 8 vo . 2 50 .

G Ru wow ( W ) K ansas : H er Resou rces an d D ev el op m ent s ; o r ,

.

t h e K an sas P i l o t 8 vo P ap e r . 50 . .

H ALL ( J am es ) Lege n d s o f t h e Wes t. S ket ch es i l l u st rat i v e o f .

th e Hab i ts, O cc u p at i o ns P ri vat i o n s Ad v en t u re s, an d Sp o r t s , ,

of t h e P i o n e er s o f t h e W es t l 2m o 2 00 . .

HALL ( J am es ) Rom an ce o f W es t e r n H i sto ry ; or S k et ch es o f

.
,

H i s to ry Li fe an d M an n ers i n t h e W es t
, . l 2m o 2 00 . .

H ANO V ER ( M D ) A P rac t i cal T reat i se o n th e Law of H or s es ,

’

. .

em b rac i n
g t h e L a w o f B a rg a i n , S al e , a n d W a r r a n t y o f H orse s

an d o t h e r Li v e S t oc k ; t h e Ru l e as to U n so u n d n ess a n d V i c e ,
an d t h e Res p o n si b i l i ty o f t h e P ro p r i et o rs o f Li v er y , Au c t i o n ,

an d S al e S tabl es I n n - k ee p ers V e t e r i n ary S u r ge o n s, an d Far

, ,

r i e rs Car r i er s , e tc
, 8 vo . 4 00 .

H A RT ( J M ) . A S y l l ab u s o f A n gl o Sax o n Li t e rat u r e
. 8y o -
. .

P ape r . 50
H AS S AU REK ( F ) T h e Sec r et of t h e An d es
. A Ro m an c e . .

l 2m o . 1 50
TH E S A ME, i n G e r m an 8v o Pa p e r c l ot h , . 1 00 .
,

H AS S AU REK ( F ) Fo u r Y ears A m o n g S p an i s h Am e r i c an s
. Th i r d .

Ed i t i o n 1 2m o
. . 1 50
H AT C H ( Col W S ) A C h ap t e r i n t h e H i s t or y o f t h e W ar o f
. . . .

1 8 12, i n t h e N or t h we s t e m b rac i n g t h e S u r re n d e r o f t h e ,

N o r t h w este r n A r m y a n d Fo r t a t D e t ro i t Au gu s t 1 6 1 8 13 e t c , , , ,
.

18 m o . 1 25
H A Y ES ( Ru th er for d B ) T h e Li fe P u b l i c S er v i c es, an d S el ec t .
,

S peec h es o f Ed i t ed b y J Q . Ho w ar d 1 2m o P ap e r 75c ; . . . . , .

Cl o t h . l 25
H AZ EN ( Ge n W B ) O u r B arre n Lan d s. . T h e I n te r i o r o f t h e
. .

U n i t e d S t a te s W e s t o f t h e O n e-
H u n d r ed t h M er i d i an , an d
,

Eas t o f t h e S i e r ra Nev ad a 8 vo P ap e r 50 . . .

H ENS R ALL ( D r J am es A ) B oo k o f t h e B l ac k B ass ; co m p r i s i n g

. .

i t s com p l e t e Sc i e n t i fi c an d Li fe Hi s tory , t o ge t h er w i t h a P rac

t i cal T r eat i se o n A n gl i n g a n d Fl y Fi s h i n g, an d a fu l l d e
sc r i p t i o n o f To ol s Tac k l e an d I m p l e m e n t s I l l u s t r a te d
, ,
. .

1211 1 0 . 3 00
H O RT O N ( S D an a) . S i l v er an d Gol d , an d t h ei r Rel ati on t o t h e
.

P ro b l em O f Resu m p t i o n 8 vo l 50 . .

HO RT O N ( S D a n a) . Th e M o n e t ar y S i t u at i on. 8v o P ap e r 50 . . .

H O UG H ( Fra n k l i n B ) El e m e n ts o f For est r y D e s i g n ed t o affo rd

. .

I n fo r m at i o n co n c e r n i n g t h e P l a n ti n g an d Car e o f Fo res t T r ees

fo r O r n am e n t an d P ro fi t ; a n d gi v i n g S u ggest i o n s u po n t h e
Cr e at i o n an d C are o f W o od l an d s w i t h t h e v i e w o f sec u r i n g ,

t h e great e s t be n e fi t fo r t h e l o n ge s t t i m e P ar t i c u l arl y ad ap t e d .

t o t h e w an ts a n d c o n d i t i o n s o f t h e U n i t ed S t a te s Il lu s .

t r at e d I 2m o
. . 2 00
H O U S ER EEP I NC I N T H E B LU E G RAS S A N e w an d P rac ti c al Coo k .

Book . B y Lad i es o f t h e P re sb y t er i an C h u rc h , P a r i s , K y .

l 2m o . 1 3 th t h o u san d 1 50
.

H O V EY ( H or ace C ) Ce l eb r ated Am er i can Cav e r n s, e sp ec i al l y

.
 Robert Clarke ( 1: Co P ubl i cati ons
’
4 s .

Mamm oth W yan d ot Lu ray ; to get h er w i t h H i stor i cal , Sci

, , an d
e n t i fi c , an d D escri ti v e N ot i c es of Cav es and G ro t toes i n O t h er
Lan d s M ap s an I l u st rati o n s 8 v o
. l 2 00 . .

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