SLE5000

Neonatal Ventilator with

High Frequency Oscillation

When the smallest thing matters

SLE5000 - The Total Solution for Infant Ventilation

The smallest thing does matter...

There are still some neonates who
cannot be adequately ventilated with
even the most sophisticated conventional
ventilation.
Indeed, using conventional ventilation
with higher rates and airway pressures
has often led to an increased incidence
of barotrauma and lung tissue damage.
High Frequency Oscillation (HFO) has
been shown to overcome this problem
whilst still allowing excellent gaseous
exchange.

A proven technique
Developed in cooperation with nurses
and doctors, the SLE5000 uses a unique
valveless system that gives both a
manageable range of HFO parameters
plus the ability to have ‘active exhalation’
Of course, the SLE5000 still has all of the Fully Featured Advanced Software
conventional ventilation modes meaning Modes include: CPAP, CMV+ TTVplus, If you already use an SLE5000 or
that it can be used on virtually any baby PTV, PSV, SIMV+ TTVplus + PSV, HFO, SLE4000 ventilator then you will know
in the NICU HFO+CMV. just how versatile the range of installed
Plus, the SLE5000 gives you: modes can be, particularly on the
User Interface SLE5000 where HFO allows you to
SLE has always worked hard to make • The ability to preset parameters in all
include a considerably larger patient
our ventilators easier to use. Essential modes of operation
demographic than with conventional
functions are never more than a couple of • Powerful HFO with active expiration ventilation.
button pushes away. Our own research to cover a wide range of patients
SLE’s Software Engineers are always
has shown that users find it much easier • Full colour, total touch-screen working on new algorithms to ensure
to use a ventilator if there are fewer sub- operation the ventilators keep up with new
menus.
• Integral flow monitoring measuring developments in medicine and user-
By reducing the number of menus and lung mechanics and displaying of feedback.
sub-menus the SLE5000 is even easier loops and waveforms The latest software, standard on all
to use when time is critical.
• Trending of measured parameters new SLE5000 and SLE4000 ventilators
The SLE5000 has a high resolution colour includes:
• Standard patient circuit for all modes
touch-screen that is your interface to
including HFO • TTVplus
all the ventilator controls and functions,
but in addition allows you to access • Unique, patented valveless • Leak compensation
many new features including trends and technology • MAP in HFO (SLE5000)
dynamic loops. • Integral battery with up to 60 • Battery indicator
The SLE5000 also features parameter minutes operating capability
• Mute all alarms
presetting, meaning that you can • Software based, allowing for
• CPAP mode alarms
choose a ventilation mode and set up all upgrading to versions with new or
parameter values before accepting these improved functions
and confirming the mode change.
Comprehensive Ventilation Features

Targeted Tidal Volume plus (TTVplus)

The SLE5000 is our first production ventilator to feature TTVplus - an entirely
new way of managing the patient’s tidal volume.
Lung protective ventilation strategies in neonates are now accepted as a
marker for improved ventilation outcome. One such strategy is the use of a
targeted tidal volume in pressure ventilation. The aim of TTVplus is to deliver
a stable tidal volume at the lowest possible pressure. All this has to occur in
the presence of a changing lung environment, that also has potential for a
variable leak around the ET tube.
TTVplus approaches this challenge by assuring a stable expired volume, with
a leak adjustment capability within safe limits. TTVplus can be used in all
conventional ventilation modes and provides a stable tidal volume control
according to your requirements.

Pressure Support Ventilation (PSV)

PSV was developed on the SLE5000 as a method to decrease the work of
breathing in-between ventilator mandated breaths by providing an elevated
pressure triggered by spontaneous breathing that supports ventilation
during inspiration. Thus, SIMV might be combined with PSV so that
additional breaths beyond the SIMV programmed breaths are supported.
Whilst the SIMV mandated breaths have a preset volume or peak pressure,
the PSV breaths are designed to cut short when the inspiratory flow
reaches a percentage of the peak inspiratory flow (e.g. 0 - 50%). It includes
automatic leak compensation thereby ensuring the flow termination of
inspiration even in the presence of a leak.
All of this means that breathing on the SLE5000 ventilator is even easier for
the smallest of babies, allowing them more energy to grow.
Without flow termination With flow termination

High Frequency Oscillation (HFO)

In the SLE5000, HFO is powerful enough to cater for a wide range of
patients from 300 g to 20 kg, dependant on lung mechanics.
The SLE5000 provides sinusoidal ventilation with active expiration.
The main benefits of HFO include:
• Improves ventilation at lower pressures
• Higher levels of PEEP can be used without having to use high peak
airway pressures to maintain appropriate levels of CO2
• Produces more uniform lung recruitment
• Reduces airleaks
• Improved oxygenation in infants with severe RDS (Respiratory Distress
Syndrome)
Features and Functions

User Interface
Colour-coded user touch
screen. Easy-to-use, logical
sequence allowing quick, smooth
adjustments.
The SLE5000’s 12.1 inch screen
means that all the data you need
can be easily seen.

Mode Panel
The mode panel is the user’s interface
to all mode related functions.

Audible and Visual Alarms

The alarm panel provides an immediate
audible and pictorial view of the
alarm condition, thus allowing easy
monitoring, plus an alarm history of the
last 100 conditions.

Pre-Setting Facility
Parameters can be preselected for
the next mode whilst continuing to
ventilate the patient in the current
mode of ventilation.

Patient Circuit Connections

Front panel mounted patient circuit
connections with (autoclavable) exhalation
block.

Principles of operation of the SLE5000 valveless system

A constant flow of fresh gas is supplied to the patient circuit at 8 l/min. The expiratory manifold has three jets (➊, ➋ and
➌). The front jet (➊) is used to generate an opposing flow to the fresh gas in the exhalation manifold and thereby creates
CPAP/PEEP.
The rear jet (➋) is used to generate the Peak Inspired Pressure (PIP) in the same way.
A third (reverse) jet (➌) is used during High Frequency Oscillation (to produce an active negative pressure) in addition to
helping eliminate excess circuit pressure.
To avoid gas dilution these jets are supplied with the same oxygen concentration as the fresh gas supply. Sophisticated
software controls the rate and duration of the flow of driving gas into the exhalation manifold in opposition to the fresh gas
flow. The opposing flow acts as a pneumatic piston and creates a pressure wave at the ET manifold.
Since the opposing flow pressure is set by pressure regulators it automatically compensates for patient and circuit
compliance changes.
 Screen Pause
Freezes waveforms for review.

Graphic Select
Allows display of real-time or
trends of flow, pressure and
volume.
Loops depicting flow/volume,
flow/pressure and volume/
pressure may also be shown.

Night Mode and Screen Lock

A low-level light mode for night time
environments with automatic screen
locking.
Auto activation on an alarm condition.

Real-time Data Display

Real-time lung mechanics
measurements and ventilatory
data.
This allows for continuous
feedback for making crucial
clinical decisions.

Compact Unit
The SLE5000 ventilator is housed
in a single compact box, making it
easier to clean and use.
The integrated touch screen is
angled for perfect visibility and
easy to read from a distance.

How does it work...?

The illustration shows the exhalation block removed
from its mountings in the ventilator. When replaced,
the jets (➊ and ➋) can create a positive pressure on
➌ ➋ ➊
flow from the patient circuits’s expiratory limb.
Jet ➌ is used to create a negative pressure and
gives true active expiration.
Since there are no valves or other blockages in the
system, there is minimal resistance to the patient.
Fewer moving parts means there is less to clean
and less risk in terms of wrong assembly or To exhaust port From expiratory limb
infection. Exhalation block
SLE5000 Patient Circuits

BC5188/100/15
Single use breathing circuit for use with SLE4000 and SLE5000 infant
ventilators. Temperature port 100 mm from ET manifold (single use).
Circuit comes complete with filter connection kit and adaptors.
Box of 15

BC5188/400/15
Single use breathing circuit for use with SLE4000 and SLE5000 infant
ventilators. Temperature port 400 mm from ET manifold (single use).
Circuit comes complete with filter connection kit and adaptors.
Box of 15

BC5488/DHW/15
Dual heated wire smooth bore breathing circuit for use with SLE4000
and SLE5000 infant ventilators. Temperature port 170 mm from ET
manifold (single use). Circuit comes complete with filter connection kit
and adaptors.
Box of 15

BC6216
Nitric Oxide delivery kit. Set of connectors.

BC2506/25
Nebuliser Kit suitable for 15 mm diameter patient circuits. For use with the BC5188, BC2188, BC5198 & BC2198
circuits.
Box of 25

BC2508/15
Nebuliser Kit suitable for 10 mm diameter patient circuits. For use with the BC5488 Circuit.
Box of 15

BC4110/KIT
Nitric Oxide adaptor kit for BC5188/100 and BC5188/400 breathing circuits (SLE4000 and SLE5000 infant ventilators).
Box of 5

BC4110/ASY
Nitric Oxide dual hose scavenging filter assembly for SLE4000 and SLE5000 infant ventilators.
Box of 1
Technical Specification

Ventilation Modes: Conventional The above values are measured under Apnoea time
CPAP / PTV / PSV ATPD (ambient temperature and pressure, Settable only in CPAP or when Backup
Inspiratory Time: 0.1 to 3.0 sec dry) conditions. rate is less than 20 BPM
CPAP Pressure: 0 to 20 mbar Range: 3 to 60 sec
Inspiratory Pressure: 0 to 65 mbar Oxygen Concentration Resolution: 1 second
Volume Targeting: 2 to 200 ml Range: 21 to 100%
FiO2: 21% to 100% (Resolution 1%) Power, Dimensions, Standards etc.
Power Requirements
CMV / SIMV Pressure Voltage : 100-250 V
BPM: 1 to 150 Real-time Pressure 50-60 Hz
I:E Ratio: (11.2:1 to 1:600) measurement: Resolution 1 mbar Power : 115 VA
Inspiratory Time: 0.1 to 3.0 sec Sampling time: 2 ms Battery back up: 45-60 minutes
PEEP Pressure: 0 to 20 mbar Peak Pressure: 0 to 175 mbar (dependant on mode of operation)
Inspiratory Pressure: 0 to 65 mbar (resolution 1 mbar) Battery charging: Full charge 24
Volume Targeting: 2 to 200 ml PEEP Pressure: 0 to 175 mbar hours, 80% charge after 8 hours
FiO2: 21% to 100% (resolution 1 mbar)
Mean Pressure: -175 to 175 mbar Outputs
Ventilation Modes: HFO Ventilation (resolution 1 mbar) RS-232C
HFO Only
Frequency Range: 3-20 Hz In HFO combined mode, Delta P is Air and O2 input
I:E Ratio: 1:1 measured during expiration only Pressures: 2.8 - 6 bar
Delta Pressure range: 4 to 180 mbar
Mean airway range: 0 to 35 mbar User Settable Alarms: Fresh Gas Flow: 8 litres/min
FiO2: 21% to 100% High Pressure
Autoset when patient pressure controls are Maximum gas flow: 60 litres/min
HFO+CMV adjusted or can be manually adjustable
BPM: 1 to 150 Range: 10 to 110 mbar Operating Environment
Inspiratory Time: 0.1 to 3.0 Resolution: 0.5 mbar Temp: 10-40 ºC
Frequency Range: 3-20 Hz Humidity: 0-90%
I:E : (11.2:1 to 1:600) Cycle Fail (non-condensing)
Inspiratory Pressure: 0 to 65 mbar Autoset when patient pressure controls are
Delta Pressure range: 4 to 180 mbar adjusted or may be manually adjusted Dimensions
Mean airway range: 0 to 35 mbar Size, ventilator only: 330mm W x
FiO2: 21% to 100% Low Pressure 330mm H x
Autoset when patient pressure controls are 470mm D
Monitoring Parameters adjusted or can be manually adjustable
Measurement of Flow and Volume Range: -10 mbar Height on trolley: 131 cm
Flow Sensor Type: 10 mm dual-hot- (Conventional)
wire anemometer (autoclavable or single -70 mbar Weight, ventilator only: 22.4 kg
use) (HFO modes) to
Flow Rate: 0.2 to 32 l/min 10 mbar below Constructed to conform to:
(Accuracy ±8%) high pressure BS EN 60601-1: 1990 +A1:93, A11:93,
Expiratory Tidal threshold A12:93, A2:95, A13:96, Corrigendum: 94
Volume: 0 to 999 ml BS EN 60101-2-12: 2006
Expiratory Minute Low Tidal Volume Medical Devices Directive (93/42/EEC)
Volume: 0 to 18 litres Range: 0 to 200 ml
Deadspace: 1 ml Resolution: 0.2 ml EMC
Weight: 10 g BS EN 60601-1-2: 2001+A1
Low Minute Volume BS EN 61000-3-2: 2006
Conventional Ventilation and combined Range: 0 to 0.02 litres BS EN 61000-3-3: 1995 +A1
modes only: below High Minute
Tube Leakage: 0 to 50% Volume threshold European conformity mark: CE 0120
(Resolution: 5%, averaged over 5 breaths) Resolution: 0.1 litre
Breath Rate (total): 0 to 150 BPM Environmental storage conditions
Dynamic Compliance: 0 to 100 ml/mbar High Minute Volume When packed for transport or storage:
(Resolution: 1 ml/mbar) Range: 0.02 to 18 litres Ambient Temperature: -40 °C to +70 °C
C20/C: Resolution 0.1 Resolution: 0.1 litre Relative Humidity : 10% to 90%
Sampling Time: 2 ms (non-condensing)
Resistance: 0 to 1000 mbar Atmospheric Pressure: 500 hPa to
/l/second 1060 hPa
Triggering: Inspiratory flow
(0.2 to 10 l/min)
 SLE is a world leader in the
design and manufacture of
neonatal ventilators.
Years of ventilation experience
have given the company an
understanding of the challenges
facing nurses and clinicians when
caring for the tiniest and most
critical babies.
From being the pioneers of
neonatal Patient Triggered
Ventilation (PTV) in the 1980’s,
to the introduction of combined
HFO (High Frequency Oscillation)
in the 1990’s, SLE has maintained
a position of strength in neonatal
ventilation.
The company’s guiding principle
is to support clinical and nursing
staff in their everyday work.
The knowledge and experience
gained during years of
development is evident in the
SLE5000 ventilator: the result of
SLE’s ongoing commitments to
innovation, competency and care.

G0006/0UK/001 04/12

SLE Limited.
Twin Bridges Business Park, 232 Selsdon Road,
South Croydon Surrey CR2 6PL UK
Telephone:+44 (0)20 8681 1414 • Fax: +44 (0)20 8649 8570
E-mail: sales@sle.co.uk • Web: www.sle.co.uk