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Chest DZ: Multiple Choice Questions

This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

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42 views3 pages

Chest DZ: Multiple Choice Questions

This document contains 14 multiple choice questions testing knowledge of various respiratory conditions and immunological concepts: 1. The questions cover topics like primary and secondary immunodeficiencies, Aspergillus infections, granuloma formation, idiopathic pulmonary fibrosis, sarcoidosis, allergic alveolitis, Kawasaki's disease, hypercalcemia in sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, T helper cell responses, mast cell distribution, skin prick testing, and the pathophysiology of asthma. 2. The answer options provide statements that are either true or false about each condition or concept being tested. 3.

Uploaded by

IM CT
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Chest Dz

Multiple Choice Questions


Question 1. Recurrent or severe bacterial pneumonia does NOT usually complicate which one
of the following conditions:
A Complement C3 deficiency.
B Primary antibody deficiencies
C Secondary immunodeficiency.
D Splenectomy.
E Immunosuppression following renal transplantation.
Question 2. Which one of the following statements about bronchial eosinophilia due to
Aspergillus fumigatus is true?
A Patients usually have chronic asthma.
B The fungus is nearly always seen on chest X-ray.
C Serum IgE levels are usually low or normal.
D Precipitating antibodies to Aspergillus fumigatus are rarely found.
E Eosinophils are never found in mucus plugs.
Question 3. The presence of which one of the following cell types defines a granuloma on
routine histology:
A T lymphocytes
B Basophils
C Erythrocytes
D Epithelioid cells
E Giant cells
Question 4. Which one of the following statements about idiopathic fibrosing alveolitis
(cryptogenic fibrosing alveolitis) is true?
A Patients are usually young.
B Antineutrophil cytoplasmic antibodies are positive in 90% of patients at presentation.
C A chest X-ray can show a ‘ground-glass’ appearance.
D 50% of patients die within 6 months of diagnosis.
E Lung transplantation is never effective in such patients.
Question 5. Sarcoidosis is characteristically associated with a positive Mantoux test.
A True
B False

Question 6. Extrinsic allergic alveolitis [EAA] is characteristically caused by


exposure to an organic dust.
A True
B False
Question 7. Kawasaki's disease often causes aortic aneurysms:
A True
B False
Question 8. Hypercalcaemia in sarcoidosis, due to abnormal vitamin D metabolism, is a
common feature.
A True
B False
Question 9. The Churg-Strauss syndrome is associated with peripheral blood eosinophilia.
A True
B False
Question 10. A first line treatment in granulomatosis with polyangiitis (formerly Wegener's
granulomatosis) is cyclophosphamide and corticosteroids.
A True
B False
Question 11. Which one of the following statements about Th responses is FALSE?
A Th2 cells produce cytokines that favour the production of IgE
B Th1 cells can be found in atopic eczema lesions.
C Th2 cells characteristically express the Foxp3 gene product
D Th2 cells produce IL-4.
E Th1 cells are associated with the transcription factor T-bet.
Question 12. Mast cells are not found in which one of the following sites?
A Dermis
B Gastrointestinal mucosa
C Epidermis
D Muscles
E Respiratory mucosa
Question 13. Which one of the following statements about skin prick testing is FALSE?
A A useful diagnostic test for respiratory allergy
B Is good for food allergy
C Can cause an anaphylactic reaction
D Is more reliable than specific IgE tests for hypersensitivity to an allergen
E Detects type I hypersensitivity reactions

Question 14. Which one of the following statements is NOT thought to be involved in asthma?

A Activation of Th1cells
B Epithelial cell activation occurs
C Upregulation of VCAM-1 results in infiltration of eosinophils
D Adrenaline is always used to reverse bronchoconstriction in mild asthmatics
E Blocking activation of mast cells with a monoclonal antibody to IgE can give clinical benefit

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