Substances Useful For The Manufacture of Drugs
Substances Useful For The Manufacture of Drugs
71
Substances useful for the manufacture of drugs
PART 1
1. The following substances, namely-
Ephedrine.
Ergometrine
Ergotamine.
Lysergic acid.
l-phenyl-2-propanone.
Pseudoephedrine.
2. The salts of all substances included in this Part, where the existence of
such salts is possible.
PART II
1. The following substances, namely-
Acetic anhydride.
Acetone.
Anthranilic acid.
Ethyl ether.
Phenylacetic acid.
Piperidine.
72
2. The salts of all substances included in this Part where the existence of
such salts is possible.
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Schedule 2
PART 1 Dependence-Producing Substances
1. The following substances, namely-
Amobarbital cyclobarbital and pentobarbital, except preparations and
mixtures containing not more than 30 milligrams per minimum
recommended or prescribed dose when intended for continued use in asthma
or containing not more than 50 milligrams per minimum recommended or
prescribed dose when intended for continued use in epilepsy.
Buprenorphine.
Chlorphentermine.
Diethylpropion (amfepramone).
Gluthethimide.
Meptazinol.
Pentazocine.
Tiletamine.
2. Unless expressly excluded, all substances included in this Part include the
following
( a)
73
The salts and esters of the specified substances, where the existence of such
salts and esters is possible: and
( b)
all preparations and mixtures of the specified substances.
PART II Dangerous Dependence-Producing Substances
1. The following substances or plants, namely-
Acetorphine.
Acetyldihydrocodeine. except preparations and mixtures containing not
more than 20 milligrams of acetyldihydrocodeine per recommended or
prescribed dose.
Acetylmethadol.
Alfentanil.
Allylprodine.
Alphacetylmethadol.
Alphameprodine.
Alphamethadol.
Alphaprodine.
Anileridine.
Benzethidine.
Benzphetamine.
Benzylmorphine.
74
Betacetylmethadol.
Betameprodine.
Betamethadol.
Betaprodine.
Bezitramide.
Chlorodyne (Chloroform and Morphine Tincture BP 1980) or any
preparation or mixture thereof described as chlorodyne, except preparations
and mixtures containing not more than 5.0 per cent of chlorodyne in
combination with other active medicinal substances.
Clonitazene.
Coca leaf and any salt. compound, derivative or preparation of coca leaf, and
any salt, compound, derivative or preparation thereof that is chemically
equivalent or identical to any of these substances, whether obtained directly
or indirectly by extraction from material or substances obtained from plants,
or obtained independently by chemical synthesis, or by a combination of
extraction and chemical synthesis, except decocainized coca leaf and
extractions of coca leaf where such extractions contain no cocaine or
ecgonine.
Codeine (methylmorphine), except preparations and mixtures containing not
more than 20 milligrams of codeine per recommended or prescribed dose.
Codoxime.
Desomorphine.
Dextromoramide.
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
75
Dextropropoxyphene, except preparations and mixtures for oral use
containing not more than 135 milligrams dextropropoxyphene, calculated as
the base, per dosage unit, or with a concentration of not more than 2.5 per
cent in undivided preparations
Diampromide.
Diethylthiambutene.
Difenoxin (or diphenoxylic acid), except mixtures containing, per dosage
unit, not more than 0.5 milligrams of difenoxin, calculated as the base, and a
quantity of atropine sulphate equal to at least 5.0 per cent of the quantity of
difenoxin, calculated as the base, which is present in the mixture.
Dihydrocodeine, except preparations and mixtures containing not more than
20 milligrams of dihydrocodeine per recommended or prescribed dose.
Dihydromorphine.
Dimenoxadol.
Dimepheptanol.
Dimethylthiambutene.
Dioxaphetylbutyrate.
Diphenoxylate, except preparations containing not more than 2.5 milligrams
of diphenoxylate, calculated as the base, and not less than 25 micrograms of
atropine sulphate per dosage unit.
Dipipanone.
Dronabinol [(-)-transdelta-9-tetrahydrocannabinol].
Drotebanol.
Ecgonine and the esters and derivatives thereof which are convertible to
ecgonine and cocaine.
76
Ethylmethylthiambutene.
Ethylmorphine, except preparations and mixtures containing not more than
20 milligrams of ethylmorphine per recommended or prescribed dose.
Etonitazene.
Etorphine.
Etoxeridine.
Fenproporex.
Fentanyl.
Furethidine.
Hydrocodone (dihydrocodeinone).
Hydromorphinol (14-hydroxydihydromorphine).
Hydromorphone (dihydromorphinone).
Hydroxypethidine.
Isomethadone.
Ketobemidone.
Levomoramide.
Levophenacylmorphan.
Levorphanol.
Mecloqualone.
Mefenorex.
Metazocine.
77
Methadone.
Methadone-intermediate.
Methorphan, including levomethorphan and racemethorphan, but excluding
dextromethorphan.
Methyldesorphine.
Methyldihydromorphine.
Methylphenidate and the derivatives thereof.
Metopon.
Moramide-intermediate.
Morpheridine.
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Morphine, except preparations and mixtures of morphine containing not
more than 0.2 per cent of morphine, calculated as anhydrous morphine.
Morphine methobromide and other pentavalent nitrogen morphine
derivatives.
Morphine-N-oxide and the derivatives thereof.
Myrophine (myristylbenzylmorphine).
Nicocodine.
Nicodicodine.
Nicomorphine.
78
Noracymethadol.
Norcodeine, except preparations and mixtures containing not more than 20
milligrams norcodeine per recommended or prescribed dose.
Norlevorphanol.
Normethadone.
Normorphine (demethylmorphine or N-demethylated morphine).
Norpipanone.
Opium and opiates and any salt, compound, derivative or preparation of
opium or opiates, whether obtained directly or indirectly by extraction from
material or substances obtained from plants, or obtained independently by
chemical synthesis, or by a combination of extraction and chemical
synthesis, except mixtures containing not more than 0.2 per cent of
morphine, calculated as anhydrous morphine.
Opium-poppy and poppy straw, whether obtained directly or indirectly by
extraction from material or substances obtained from plants, or whether
obtained independently by chemical synthesis, or by a combination of
extraction and chemical synthesis.
Oxycodone (14-hydroxydihydrocodeinone or dihydrohydroxycodeinone).
Oxymorphone (14-hydroxydihydromophinone or
dihydrohydroxymorphinone).
Pethidine. pethidine-intermediate A, pethidine-intermediate B and
pethidineintermediate
C. Phenadoxone.
Phanampromide.
Phenazocine.
Phendimetrazine.
Phenomorphan.
79
Phenoperidine.
Pholcodine. except preparations and mixtures containing not more than 20
milligrams of pholcodine per recommended or prescribed dose.
Piminodine.
Piritramide.
Proheptazine.
Properidine.
Propiram.
Racemoramide.
Racemorphan.
Secobarbital.
Sufentanil
Thebacon.
Thebaine.
Tilidine.
Trimeperidine.
2. Unless expressly excluded, all substances or plants included in this Part
include the following:
( a)
The isomers of the specified substances or plants, where the existence of
such isomers possible;
80
( b)
the esters and ethers of the specified substances or plants and of the isomers
referred to in subparagraph ( a), as well as the isomers of such esters and
ethers, where the existence of such esters, ethers and isomers is possible;
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
Sch. 2 Drugs and Drug Trafficking Act, No.140 of1992 Sch. 2
( c)
the salts of the specified substances or plants, of the isomers referred to in
subparagraph ( a) and of the esters, ethers and isomers referred to in
subparagraph ( b), as well as the isomers of such salts, where the existence
of such salts and isomers is possible; and
( d)
all preparations and mixtures of the specified substances or plants and of the
isomers, esters, ethers and salts referred to in this paragraph.
PART III Undesirable Dependence-Producing Substances
1. The following substances or plants, namely-
Amphetamine.
Brolamfetamine.
Bufotenine (N,N-dimethylserotonin).
Cannibis (dagga), the whole plant or any portion thereof, except dronabinol
[(-)-transdelta-9-tetrahydrocannabinol].
Cathinone.
Dexamphetamine.
81
Diethyltryptamine [3-(2-(diethylamino)-ethyl)-indole].
2,5-dimethoxyamphetamine (DMA).
2,5-dimethoxy-4-ethylamphetamine (DOET).
3-(1,2-dimethylheptyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo [b,
d] pyran-1-01 (DMHP).
Dimethyltryptamine [3-(2-(dimethylamino)-ethyl)-indole].
Fenetylline.
Fentanyl-analogues:
acetyl-alpha-methyl-fentanyl;
alpha-methyl-fentanyl;
alpha-methyl-fentanyl-acetanilide;
alpha-methyl-thio-fentanyl;
benzyl-fentanyl;
beta-hydroxy-fentanyl;
beta-hydroxy-3-methyl-fentanyl;
3-methyl-fentanyl and the two isomeric forms thereof, namely,
cis-N-(3-methyl-1-(2-phenethyl)-4-piperidyl)propionanilide and trans-N-(3-
methyl-1-(2-phen-ethyl)-4-piperidyl)propionanilide;
3-methyl-thio-fentanyl;
para-fluoro-fentanyl; and
thiofentanyl.
82
Harmaline (3,4-dihydrobarmine).
Harmine [7-methoxy-1-methyl-9H-pyrido (3,4-b)-indole].
Herion (diacetylmorphine). Levamphetamine. Levomethamphetamine.
Lysergide (lysergic acid diethylamide).
Mescaline (3,4,5-trimethoxyphenethylamine).
Methamphetamine and methamphetamine racemate.
Methaqualone, including Mandrax. lsonox. Quaalude, or any other
preparation containing metha-qualone and known by any other trade name.
2-methoxy-4,5-methylenedioxyamphetamine (MMDA).
4-methylaminorex.
4-methyl-2,5-dimethoxyamphetamine (DOM) and the derivatives thereof.
Methylenedioxyamphetamine (MDA):
N-ethyl-methylenedioxyamphetamine; and
N-hydroxy-methylenedioxyamphetamine.
Schs. 2-3 Drugs and Drug Trafficking Act, No.140 of1992 Schs. 2-3
Schs. 2-3 Drugs and Drug Trafficking Act, No.140 of1992 Schs. 2-3
Nabilone.
Parahexyl.
Paramethoxyamphetamine (PMA).
Phencyclidine and the congeners thereof, namely, N-ethyl-1-
phenylcyclohexylamine (PCE), 1-(1-phenylcyciohexyl) pyrrolidine (PHP or
PCPY) and 1-[1-(2-thienyl) cycohexyl] piperidine (TCP).
83
Pethidine-analogoues:
1-methyl-4-phenyl-4-propionoxy-piperidine (MPPP);
1-methyl-4-phenyl-l,2,5,6-tetrahydropiperidine (MPTP); and
1-phenylethl-4-phenyl-4-acetyloxy-piperidine (PEPAP).
Phenmetrazine.
Psilocin (4-hydroxydimethyltryptamine).
Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine).
Tetrahydrocannabinol
3,4,5-trimethoxy amphetamine (TMA).
2. Unless expressly excluded, all substances or plants included in this Part
include the following:
( a)
The isomers of the specified substances or plants, where the existence of
such isomers is possible;
( b)
the esters and ethers of the specified substances or plants and of the isomers
referred to in subparagraph ( a) as well as the isomers of such esters and
ethers, where the existence of such esters, ethers and isomers is possible;
( c)
the salts of the specified substances or plants, of the isomers referred to in
subparagraph ( a) and of the esters, ethers and isomers referred to in
subparagraph ( b), as well as the isomers of such salts, where the existence
of such salts and isomers is possible; and
84
( d)
all preparations and mixtures of the specified substances or plants and of the
isomers, esters, ethers and salts referred to in this paragraph.
Schedule 3 LAWS REPEADED (SECTION 66)