Safety Data Sheet
Safety Data Sheet
2. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW: Colorless, volatile liquid with ethereal and faint sweetish odor. Non-flammable material.
Overexposure may cause dizziness and loss of concentration. At higher levels, CNS depression and cardiac arrhythmia
may result from exposure. Vapors displace air and can cause asphyxiation in confined spaces. At higher temperatures,
(>250C), decomposition products may include Hydrochloric Acid (HCI), Hydrofluoric Acid (HF) and carbonyl halides.
SKIN: Prolonged and/or repeated contact with this solvent can cause irritation of the skin (defatting of skin).
EYES: Irritant. Liquid contact will irritate and may cause conjunctivitis.
INHALATION: When oxygen levels in air are reduced to 12-14% by displacement, symptoms of asphyxiation, loss of
coordination, increased pulse rate and deeper respiration will occur. Overexposure to vapors may cause
temporary anesthetic effects such as dizziness, headache and confusion. At higher levels, cardiac
arrhythmia may occur.
In repeated exposure tests with animals, changes were noted in liver functions and lipid production at levels
above 100 ppm. In isolated incidents with workers, overexposure to solvent vapors resulted in elevated
liver enzyme levels. Liver enzyme levels returned to normal after overexposure ceased.
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INGESTION: Discomfort due to volatility would be expected. Some of the inhalation effects could be expected.
DELAYED EFFECTS: No delayed effects of a single exposure have been identified. Delayed effects of multiple exposure
are seen in animal studies by the formation late developing benign tumors. Repeated
overexposure to vapor may result in elevated liver enzyme levels.
Ingredients found on one of the OSHA designated carcinogen lists are listed below.
There are no impurities or stabilizers that contribute to the classification of the material identified in Section 2
SKIN: Promptly flush skin with water until all chemical is removed. Remove clothing contaminated with liquid and wash before
use.
EYES: Immediately flush eyes with large amounts of water for at least 15 minutes, lifting eyelids occasionally to facilitate irrigation.
Get medical attention.
INHALATION: Immediately remove patient to fresh air. If breathing has stopped, give artificial respiration. Use oxygen as
required, provided a qualified operator is available. Get medical attention immediately. DO NOT give epinephrine
(adrenaline).
INGESTION: DO NOT induce vomiting unless instructed to do so by a physician. DO NOT give stimulants. Get medical
attention immediately.
ADVICE TO PHYSICIAN: Because of the possible disturbances of cardiac rhythm, catecholamine drugs, such as
epinephrine, should be used with special caution and only in situations of emergency life support.
Treatment of overexposure should be directed at the control of symptoms and the clinical
conditions.
FLAMMABLE PROPERTIES
FLASH POINT: None
FLASH POINT METHOD: ASTM D-1310-67 and ASTM D-56-82
AUTOIGNITION TEMPERATURE: 770C
UPPER FLAME LIMIT (volume % in air): None
LOWER FLAME LIMIT (volume % in air): None
FLAME PROPAGATION RATE (solids): Not applicable
OSHA FLAMMABILITY CLASS: Not applicable
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EXTINGUISHING MEDIA:
Use any standard agent – choose the one most appropriate for type of surrounding fire (material itself is not flammable)
Solvent vapors, when present in the flammable range (listed above), especially in a confined or poorly ventilated space, can
be ignited with a flame or high intensity source of heat.
IN CASE OF SPILL OR OTHER RELEASE: (Always wear recommended personal protective equipment.)
Evacuate unprotected personnel and provide maximum ventilation. Protected personnel should eliminate all ignition sources
if without risk. Only personnel equipped with proper respiratory and eye/skin protection should be permitted in the area.
Dike area to contain the spill. Take precautions as necessary to prevent contamination of ground and surface waters. For
large spills, pump solvent into appropriate containers. For small spills, recover or absorb spilled material using an absorbent
designed for chemical spills such as Hazsorb® pillows. Place used absorbents into closed DOT approved containers for
disposal. After all visible traces have been removed, thoroughly wet vacuum the area. DO NOT flush into sewer. If the
area of the spill is porous, removal of contaminated earth/surface may be required.
Spills and releases may have to be reported to Federal and/or local authorities. See Section 15 regarding reporting
requirements.
2. Carefully remove the ¾ inch plug from the center of the large bung. DO NOT puncture the inner seal.
3. Insert convenient length ¾ inch nipple fitted with a closed valve. As nipple is inserted, the inner seal is broken and container is
ready to unload through valve
STORAGE RECOMMENDATIONS:
Keep container closed when not in use. DO NOT store in open, unlabeled or mislabeled containers. Store in a cool, well-
ventilated area of low fire risk. Protect container and its fittings from physical damage. Storage in subsurface locations
should be avoided. Close valve tightly after use and when empty. If container temperature exceeds boiling point, cool the
container before opening
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INCOMPATIBILITIES: Alkali metals. Alkaline earth metals. Powdered metals. Powdered metal salts.
ENGINEERING CONTROLS:
Use local exhaust at filling zones and areas where leakage is probable. Use mechanical (general) ventilation for storage
areas. All ventilation should be designed in accordance with OSHA standard (29 CFR 1910.94). Concentration of R-123
should be monitored and kept below the recommended levels in work areas.
SKIN PROTECTION:
Use protective, impervious gloves and apron constructed of butyl rubber (2 nd choice: viton or neoprene), if
prolonged or repeated contact with liquid is anticipated. Any non-impervious clothing should be promptly removed
when contaminated and washed before reuse.
EYE PROTECTION:
For normal conditions, wear safety glasses. Where there is reasonable probability of liquid contact, wear splash-
proof goggles.
RESPIRATORY PROTECTION:
None generally required for adequately ventilated work situations. Where concentrations are above the
recommended (* Workplace Environmental Exposure Level of 50 ppm TWA), use NIOSH-approved organic vapor
canister respirator. For large spills or non-ventilated situations where concentrations are significantly above the
recommended TLV, use a NIOSH-approved supplied air respirator.
ADDITIONAL RECOMMENDATIONS:
High dose-level warning signs are recommended for areas of principle exposure. Provide eyewash stations and
quick-drench shower facilities at convenient locations. For tank cleaning operations, see OSHA regulations, 29
CFR 1910.132 and 29 CFR 1910.133.
EXPOSURE GUIDELINES
INGREDIENT NAME ACGIH TLV OSHA PEL OTHER LIMIT
Dichlorotrifluoroethane None None * 50 ppm TWA
INCOMPATIBILITIES:
Freshly abraded aluminum surfaces (may cause strong exothermic reaction). Chemically active metals for example sodium,
potassium, calcium, magnesium, zinc, or powdered aluminum.
HAZARDOUS POLYMERIZATION:
Will not occur.
OTHER DATA:
No reproductive effects were seen in a two-generation, inhalation reproduction study although a retarded rate of weight gain
and lower pup weights were noted. These effects were seen at inhalation concentrations above 30 ppm for animals exposed
throughout the test. A follow-up Cross Fostering study confirmed that these body weight gain effects were the direct result
of exposure of the pups to either HCFC-123 or its metabolite, Trifluoroacetic acid, through the maternal milk and not a
reproductive or developmental effect.
Six genetic assays were run, five of which were negative. The sixth, chromosome aberration of human lymphocytes, was
weakly positive.
In isolated instances, some workers overexposed to HCFC-123, were found to have elevated liver enzymes. The liver
enzyme levels returned to normal when the worker overexposure ceased.
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POTENTIAL HEALTH HAZARDS
SKIN: Prolonged and/or repeated contact with this solvent can cause irritation of the skin (defatting of skin).
EYES: Irritant. Liquid contact will irritate and may cause conjunctivitis.
INHALATION: When oxygen levels in air are reduced to 12-14% by displacement, symptoms of asphyxiation, loss of
coordination, increased pulse rate and deeper respiration will occur. Overexposure to vapors may cause
temporary anesthetic effects such as dizziness, headache and confusion. At higher levels, cardiac
arrhythmia may occur.
In repeated exposure tests with animals, changes were noted in liver functions and lipid production at levels
above 100 ppm. In isolated incidents with workers, overexposure to solvent vapors resulted in elevated
liver enzyme levels. Liver enzyme levels returned to normal after overexposure ceased.
INGESTION: Discomfort due to volatility would be expected. Some of the inhalation effects could be expected.
DELAYED EFFECTS: No delayed effects of a single exposure have been identified. Delayed effects of multiple exposure
are seen in animal studies by the formation late developing benign tumors. Repeated
overexposure to vapor may result in elevated liver enzyme levels.
Ingredients found on one of the OSHA designated carcinogen lists are listed below.
Biodegradability - Minimal
Daphnia Magna LC50 = 17.3 mg/L
Rainbow Trout LC50 = 55.5 mg/L
Green Algae – LC50 = 96.6 mg/L
Octanol Water Partition Coefficient: Log P ow = 2.307 (estimated)
RCRA
Is the unused product a RCRA hazardous waste if discarded? Not a hazardous waste.
If yes, the RCRA ID number is: Not applicable
The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with other materials
may significantly change the characteristics of the material and alter the RCRA classification and the proper disposal method.
Spills or releases resulting in the loss of any ingredient at or above its RQ requires immediate notification to the
National Response Center [(800) 424-8802] and to your Local Emergency Planning Committee.
STATE RIGHT-TO-KNOW
In addition to the ingredients found in Section 2, the following are listed for state right-to-know purposes.
WARNING: DO NOT VENT TO THE ATMOSPHERE. TO COMPLY WITH PROVISIONS OF THE U.S. CLEAN AIR
ACT, ANY RESIDUAL MUST BE RECOVERED. CONTAINS DICHLOROTRIFLUOROETHANE
This product has been evaluated in accordance with the hazard criteria of the CPR and the MSDS contains all the information
required by the CPR.
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FOREIGN INVENTORY STATUS:
EINECS (EU) # 2061903 Korean ECL and Canadian DSL
CHANGES TO MSDS FROM PREVIOUS ISSUE DATE ARE DUE TO THE FOLLOWING:
Section 8: Updated ACGIH-TLV for HF decomposition product
Section 15: Updated TSCA information
DISCLAIMER:
National Refrigerants, Inc. believes that the information and recommendations contained herein (including data and statements are
accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF
MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE
INFORMATION PROVIDED HEREIN. The information provided herein relates only to the specific product designated and may not
be valid where such product is used in combination with any other methods of use of the product and of the information referred to
herein are beyond the control of National Refrigerants. National Refrigerants expressly disclaims any and all liability as to any results
obtained or arising from any use of the product or reliance on such information.
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Current Issue Date: May 2018