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Medication: Expected Pharmacological Action Therapeutic Use

Hydrochlorothiazide, chlorthalidone, and chlorothiazide are thiazide diuretic medications used to treat hypertension, edema, and hypokalemia. They work by blocking sodium and chloride reabsorption in the distal convoluted tubule, promoting diuresis. Potential complications include dehydration, hypokalemia, hyperglycemia, and hyperuricemia. The medications are administered orally with food to reduce GI side effects and require monitoring of electrolytes, blood pressure, weight, and urine output.

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Mike Everette
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186 views1 page

Medication: Expected Pharmacological Action Therapeutic Use

Hydrochlorothiazide, chlorthalidone, and chlorothiazide are thiazide diuretic medications used to treat hypertension, edema, and hypokalemia. They work by blocking sodium and chloride reabsorption in the distal convoluted tubule, promoting diuresis. Potential complications include dehydration, hypokalemia, hyperglycemia, and hyperuricemia. The medications are administered orally with food to reduce GI side effects and require monitoring of electrolytes, blood pressure, weight, and urine output.

Uploaded by

Mike Everette
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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ACTIVE LEARNING TEMPLATE: Medication

Michael Everette
STUDENT NAME______________________________________
Hydrocholorothiazide, Chlorthalidone, Chlorothiazide
MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER__144
__________

CATEGORY CLASS__Thiazide Diuretic (thiazide like)


_____________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Therapeutic Use


Early distal convoluted tubule First choice med for hypertension
Edema of mild to moderate heart failure & liver/kidney disease
Blocks re-absorption of sodium & chloride & In combo w. antihypertensive agents for BP control
prevents reabsorption of water at site Reduce urine production in clients with diabetes insipidus
Promotes reabsorption of calcium and can reduce the risk for postmenopausal
Promote diuresis when renal function is not impaired osteoporosis

Complications Medication Administration


Dehydration & hyponatremia Chlorothiazide is administered
Hypokalemia & hypochloremia orally & IV
Hyperglycemia Chlorthalidone &
Hyperuricemia, hypomagenesemia, increased lipids Hydrochlorothiazide given orally
Administer w. food to reduce GI
effects

Contraindications/Precautions
Contraindications: clients w. renal impariment
Precautions: clients w. DM, hypokalemia, hyperlipidemia, Nursing Interventions
hypomagnesemia, & gout
clients take digoxin, lithium, or antihypertensives Monitor BP & I&O
Monitor K+ levels
Monitor orthostatic BP, weight,
electrolytes & location and
Interactions extent of edema

Lithuim toxicity can occur


NSAIDs can reduce effectiveness
Can be combined w. ototoxic meds

Client Education
Take med first thing in the AM
Consume food high in K+ & maintain adequate
Evaluation of Medication Effectiveness fluid intake (1500 mL/day)
Take meds after meals if GI upset occurs
Self monitor BP & weight (for hypertension)
Decrease in BP Report significant weight loss, lightheadness, GI
Decrease in edema distress
Increase in urine output Monitor elevated blood glucose levels (for
diabetes)
Reduced urine output in diabetes insipidus Observe for low magnesium levels, weakness,
Preserved bone integrity in postmenopausal clients muscle twitching & tremors

ACTIVE LEARNING TEMPLATES

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