Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.

Sc (Chemistry)

M. Sc [Chemistry] – Curriculum & Syllabus

(with effect from 2018-2019)

SEMESTER-I
Core/ Credits/ Duration of Marks
Subject Code Elective Title of the Paper Hrs. per Semester Total Marks
week Exam IA EA
Core Crystalline State and Inorganic Clusters 4 3 40 60 100
Core Principles of Organic Chemistry 4 3 40 60 100
Core Chemical Kinetics and Group Theory 4 3 40 60 100
Core Analytical Chemistry 4 3 40 60 100
Inorganic Chemistry Laboratory (6*) To be continued in semester II
Organic Chemistry Laboratory (6*) To be continued in semester II
Physical Chemistry Laboratory (6*) To be continued in semester II
Theory 16
Distribution of working hours / Week Seminar 2 Hours
Hours/credits
SEMESTER –II
Core Coordination Chemistry 4 3 40 60 100
Core Organic Transformations 4 3 40 60 100
Core Thermodynamics and Quantum Chemistry 4 3 40 60 100
Core Advanced Analytical Methods 4 3 40 60 100
Inorganic Chemistry Laboratory 6 6 40 60 100
Organic Chemistry Laboratory 6 6 40 60 100
Physical Chemistry Laboratory 6 6 40 60 100
Theory
Practical 18
Distribution of working hours / Week 16Hours/
Hours/credits
credits
SEMESTER-III (Any one elective paper has to be chosen)
Core Physical Methods in Inorganic Chemistry 4 3 40 60 100
Core Organic Spectroscopy 4 3 40 60 100
Core Electrochemistry and Spectroscopy 4 3 40 60 100
Core Organic Reagents & Reactions 4 3 40 60 100
Elective-1 Green Chemistry
Elective-2 Polymer chemistry 4 3 40 60 100
Elective-3 Nanomaterials
Analytical Chemistry Laboratory 6 6 40 60 100
Theory 20 Practical
Hours/credits 6Hours/credits
SEMESTER-IV (Any Two elective papers have to be chosen)
Core Soft Skills and Scientific Writing 4 3 40 60 100
Core Surface Chemistry and Photo Chemistry 4 3 40 60 100
Elective-1 Synthetic Organic Chemistry 4
3 40 60 100
Elective-2 Nuclear and Bioinorganic Chemistry
Elective-3 Supramolecular Chemistry
4 3 40 60 100
Elective-4 Crystal Growth
Comprehensive Viva 2 - - 100 100
Project Work and Viva-Voce 6 - - 100 100
Theory 16 Viva and project &
Distribution of working hours / Week
Hours/credits viva-voce 8 credits
TOTAL CREDITS 100

(*) total credits for one year TOTAL MARKS 2300

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

I - Crystalline State and Inorganic Clusters 4 0 0 4

Aim: To make the student to appreciate the effect of symmetry on properties of crystals, utility of
XRD in structure determination.

Objective:
 Understanding on properties of solids on the basis of the internal structure of the
crystals.
 Understanding on various types of inorganic clusters.

Outcome:
 Successful completion of the course the students should have knowledge about the X-ray
crystallography.

Unit-I Crystal structure (15 hrs)

Types of solids – crystalline state – order – unit cell- lattice – types – lattice planes- Miller
indices.Crystal geometry – symmetry – symmetry elements –space groups – types of crystals-
Reciprocal lattice – construction – properties – reciprocal lattices of SC,BCC and FCC lattices -
Ewald’s sphere -X-ray Diffraction – Bragg’s law – methods of diffraction – single crystal –
powder crystal and rotating crystal methods -Crystal structure determination – scattering factor –
structure factor –phase problem –space group determination.

Unit-II Structure of Ionic Solids (15 hrs)

Properties of ionic solids – lattice energy – Born-Haber cycle -Packing of atoms – AB and ABC
structures – radius ratio rules - Structure of simple ionic solids - AX type NaCl, CsCl, ZnS –
AX2 type CaF2, TiO2 – layered structures NiAs,CdI2 and MoS2 -Structures of spinels and
Perovskite.

Unit-III Defects and electronic structure of solids (15 hrs)

Crystal defects – types - point, line and plane defects – Schottky and Frenkel defects – colour
centers thermodynamics of defect formation – non stoichiometric crystals – consequences of
defects.Band theory – refinement of simple band theory – k-space – conductors, insulators and
semiconductors on the basis of band theory.Superconductivity – photoconductivity – dielectric
properties – pyroelectricity and piezoelectricity ( Basic concepts only)

Unit-IV Properties and applications of solids (15 hrs)

Magnetic materials - metals and alloys – metal oxides –garnets – ilmenites – magneto plumbites
– applications – transformer cores – information storage – memory devices – permanent
magnets.Solid state electrolytes – types - examples – applications – electrochemical cells –
batteries- sensors and fuel cells.Crystallization – growth of single crystals – Czochralski –
Bridgman and Stockbarger – zone melting - melt :flux methods

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Inorganic Rings chains and Clusters (15 hrs)

Silicates – chain silicates - 2D and 3D silicates – Beryls – Muscovite – aluminosilictaes –
zeolites( structures only)-Carboranes – types- nomenclature – metalloboarnes (Structures only)-
classification-Metal clusters – Re2Cl8 type clusters – structure – qualitative MO diagram –
quadruple bond

Text Books
I. Chaklrabarthy.D.K, Solid state chemistry, New Age India limited, 2005.
II. Velmurugan.D, Elementary crystallography, MJP Publishers, 2010.
III. West Anthony R. Solid State Chemistry and Its Applications. Wiley, 2014
IV. Shriver and Atkins , Inorganic Chemistry, Oxford University Press,2014

Reference Books
1. James Huheey, Ellen A.Keiter and Richard L.Keiter , Inorganic Chemistry Principles of
Structure and Reactivity, Pearson Education Asia, 2001.
2. J.D. Lee, Concise Inorganic ChemistryWiley India Ltd., Sixth edition, 2008
3. Gurdeep Raj, Advanced Inorganic Chemistry, Eleventh edition, Vol. II, Goel Publishing
House, 2008.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

I - Principles of Organic Chemistry 4 0 0 4

Aim: To learn about Reaction intermediates and stereochemistry of compounds.

Objectives:
 To learn the Nucleophilic Substitution and Electrophilic Substitution Reactions
 To understand the different types of organic reactions.

Outcome:
 Understanding on organic reaction kinetics and stereochemistry of reactions.
 Understanding on various types of organic reaction and reaction intermediates.

Unit-I Reaction intermediates (15 hrs)

Nomenclarure of aromatic and heteroaromatic compounds: Hetero cyclics with not more than
two heteroatoms (oxygen/sulfur/nitrogen)
Stability, generation and applications of carbocations, carbanions, free radicals, carbenes,
nitrenes, benzynes.ylides, enamines.

Unit-II Reactions: mechanisms and their determinations (15 hrs)

Principle of Equilibria and free energy, free energy change in relation to bond strengths,
activation energy, measurement of activation energy, reaction profile diagrams, rate determining
step, thermodynamic and kinetic control, applications of kinetic principles (Hammond postulate,
effect of solvent on reaction rate), Curtin-Hammett principle, Hammett equation,Swain-Scott
equation, Grunwald-Winstein equation,microscopic reversibility, methods of determining
mechanisms.

Unit-III Stereochemistry I (15 hrs)

Stereoisomerism: Introduction, molecular representation, classification of isomers based on:
symmetry criterion, energy criterion, stereoisomerism, conformation and chirality.
Nomenclature: Fischer’s D and L and R and S. E and Z nomenclature, Stereochemistry of
allenes, Biphenyl derivatives and atropisomerism, Stereoselective and stereospecific reactions,
Homotopic, enantiotopic and diastereotopic ligands (definitions only)

Unit-IV Stereochemistry II (15 hrs)

Stereochemistry of cyclic and acyclic systems, conformations of ethane, 1,2-disubstituted
ethanes, effect of conformation on reactivity (E2 elimination, Curtin-Hammett principle,
Wagner-Meerwein rearrangement. Conformations of cyclopentane, cyclohexane, methyl
cyclohexane, 1,2- 1,3- and 1,4-dimethyl cyclohexanes. Molecular dissymmetry and chirotropic
properties, circular birefringence, and circular dichroism, Cotton effect, applications of ORD and
CD, Axial halo ketone rule, Octant ruleconformational effects on reactivity (Ester hydrolysis
with a base, Cyclohexnol oxidation with chromium trioxide and water, Intramulecular closure of
halohydrin to form epoxide), NGP, Determination of 2-amino cyclohexanol

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Nucleophilic Substitution Reactions (15 hrs)

Aliphatic nucleophilic substitution reactions- Introduction, SN mechanism, SN1 mechanism,
2

(effects of substrate, attacking nucleophile, leaving group and solvent), SN1 vs SN2 reactions,
neighboring group participation and non-classical carbocations. Aromatic nucleophilic
substitution reactions – SNAr general mechanism, Aryl cation mechanism, benzyne mechanism.

Text books:
I. D. Nasipuri, Stereochemistry Organic Compounds, Principles and applications, Second
edition, New Age International (P) Ltd., 1994, Reprint 2008.
II. P.S. Kalsi, Stereochemistry Conformation and Mechanism, Seventh edition, , New Age
International Publishers, 2008.
III. P.S. Kalsi, Organic Reactions and their mechanisms, Third edition, New Age
International Publishers, 2010.
Reference Books:
1. Jerry March, Advanced Organic Chemistry, Reactions, Mechanisms and structures,
Wiley Students edition, 2006.
2. F.A. Carey and R.I. Sundberg, Advanced Organic Chemistry, Part A & B, 5th Ed.,
Springer, 2009.
3. V.K. Ahluwalia, R.K. Parashar, Organic Reaction Mechanisms, Third edition, Narosa
Publishing House, 2009.
4. Peter Sykes, A guide book of mechanism in organic chemistry, Pearson, 6th Ed., 2006.
5. Ernest.L.Eliel,Samuel H.Wilen,L.N.Mander, Stereo chemistry of Organic compounds,
John Wiley & Sons., New York, 2003.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

I - Chemical Kinetics and Group Theory 4 0 0 4

Aim: To study about Chemical Kinetics and Group Theory

Objectives:
 To understand the concepts and applications of reaction kinetics.
 To understand the symmetry of molecules and its applications.

Outcome:
 Students will get an idea about the applications of Group Theory to various Molecules.

Unit-I Theories of reaction rates (15 hrs)

Effect of temperature on reaction rates, Arrhenius equation for simple reactions, Energy of
activation, Potential energy surfaces, an introduction, Collision theory, factors affecting effective
collision, Weakness of collision theory, reaction cross section, comparison with Arrhenius
equation, Transition state theory, thermodynamic treatment, Unimolecular reactions,
Lindemann’s mechanism, Rice Ramsperger Kassel (RRK) model.

Unit-II Complex reactions (15 hrs)

Kinetics of reversible reactions, consecutive and parallel reactions,Kinetics of chain reactions,
H2&Br2, H2 & O2, decomposition of CH3CHO & N2O5, Study of fast reactions, flow technique,
stopped flow techinique, temperature and pressure jump methods, shock tubes.

Unit III Reactions in solutions (15 hrs)

Solvent effects, factors affecting reactions rates, ARRT as applied to solution phase, effect of
internal pressure, reactions between ions, single sphere and double sphere mechanisms, influence
of ionic strength, pressure and dielectric constant, volume of activation, diffusion controlled
reactions: an introduction, Linear free energy relations, Hammett equation.

Unit-IV Group theory – fundamentals (15 hrs)

Theory of groups, classes, sub groups, similarity transformations, point group classification,
isomorphism, Matrix representation of symmetry operations, reducible and irreducible
representations, decomposition of irreducible representation in to reducible representation,
properties of irreducible representation, notations and theorems related to irreducible
representations, Projection operator, theorems of representation, construction of character tables
for C2v and C3v point groups, direct product representation.

Unit-V Group theory – applications (15 hrs)

Applications of group theory to molecular vibrations (H2O & ethylene), group theoretical
treatment of hybridization (methane & boron trifluoride), SALC procedure for butadiene.
Electronic spectrum of formaldehyde,Selection rules for IR and Raman spectrum, Woodward
and Hoffmann rules.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. J. Rajaram, J. C. Kuriacose, Kinetics and Mechanisms of Chemical Transformations, First
edition, Macmillan, 1993, reprint 2011.
II. Peter Atkins, Julio de Paula, Physical Chemistry, Eighth edition, Oxford press, 2006.
III. P.C. Jain and Monika Jain, Engineering Chemistry, 15th editionDhanpat Rai
Publishing Co., 2008.
IV. F.A. Cotton, Chemical Applications of Group Theory, Third edition, John Wiley & Sons,
1990, reprint 2006.
V. M.S.Gopinathan and V. Ramakrishnan, Group theory in Chemistry, Second edition, Vishal
Publications, 1991, reprint 2001.

Reference Books
1. Donald A. Mcquarrie, John D. Simon, Physical Chemistry, First edition, Viva
Books,1998.
2. K. Veera Reddy, Symmetry and Spectroscopy of Molecules, Second edition, New Age
International, 2009.
3. Keith.J. Laidler, Chemical Kinetics, Third Edition, Pearson Education, 2004.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

I - Analytical Chemistry 4 0 0 4

Aim: To Understand the basic concepts of analytical techniques

Objective:
 To impart the knowledge of various analytical chemistry methods.

Outcome:
 The students will acquire knowledge of,
 Data handling and statistical treatment of data
 Principles of wet analytical methods, thermal analytical methods, optical methods,
chromatographic techniques and electro analytical techniques and its applications

Unit-I Errors & Laboratory Procedures (15 hrs)

Significant figures, rules for determination, definition and classification of errors, accuracy and
precision, methods of expressing accuracy (absolute error, relative error), comparison between
accuracy and precision, methods of expressing precision (mean, median, range, standard
deviation, variance), test of significance (F-test, chi square test, Q-test). Classification of
chemicals, rules for handling reagents and solutions, measurement of mass (Electronic analytical
balance only)

Unit-II Wet Analysis (15 hrs)

Volumetric analysis – acid base, redox & complexometric titrations- theory and experiment.
Gravimetric analysis - precipitation methods- homogeneous precipitation-filtration, washing,
drying, weighing-Colorimetric analysis – photoelectric colorimeter – single beam and double
beam schematic diagrams, applications.

Unit-III Thermal and Spectral Methods (15 hrs)

Thermal Analysis: TGA, DTA, DSC - principles, instrumentation and applications. Spectral
Methods: UV-Visible spectroscopy- Beer Lamberts Law, Description of UV-Vis
spectrophotometer Applications of UV- Visible spectroscopy -Infrared spectroscopy –
instrumentation, single beam and double beam spectrometers, sample handling, FTIR
spectrometer

Unit-IV Chromatographic Techniques (15 hrs)

Paper Chromatography – theory, techniques and applications. Column Chromatography –
principles, experimental requirements, identification of compounds and applications. Thin layer
Chromatography – theory, techniques and applications. Gas Chromatography – principle, theory,
instrumentation, identification of chromatogram. High Performance Liquid Chromatography –
instrumentation and applications.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Electroanalytical Methods (15 hrs)

Conductometric titrations – principle, practice and applications-Amperometric titrations –
principle, instrumentation and applications-Potentiometry – instrumentation, electrodes,
potentiometric titrations-pHmetry -Glass electrode and Ion selective electrodes-
Electrogravimetry – theory, electrolysis at constant current and constant voltage-principle,
experimental set up and applications-Coulometry – coulomb calculation, silver coulometer,
constant current Coulometry.

Text Books
I. Dhruba Charan Dash, Analytical Chemistry, PHI Learning Private Ltd., 2011.
II. H. Kaur, Instrumental Methods of Chemical Analysis, Sixth edition, Pragati Prakashan,
2010.
III. Douglas A. Skoog, Donald M. West, F. James Holler, Analytical Chemistry An
Introduction, Sixth Edition, Saunders College Publishing, 1994.

Reference Books
1. Douglas A. Skoog, F. James Holler, Stanley R. Crouch, Instrumental Analysis,
Brooks/Cole Cengage Learning (I) Pvt. Ltd.,, First Indian Reprint 2008.
2. Gurdeep R. Chatwal, Sham K. Anand, Instrumental Methods of Chemical Analysis, Fifth
edition, Himalaya Publishing Company, 2007.
3. H.H. Willard, L.L. Merritt Jr., J.A. Dean, F.A. Settle, Instrumental Methods of Analysis,
Seventh edition, CBS Publishers & Distributors, 1986.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Coordination Chemistry 4 0 0 4

Aim: To understand the basic principles of coordination chemistry

Objectives:
 Learning about the various theories of complex formation.
 Studying and interpreting the magnetic properties of complexes .

Outcome:
 Students will get an idea about basics of metal complex formation and explain the
properties of complexes on the basis of CFT and MOT.

Unit-I Theories of metal complexes (15 hrs)

Co-ordination compounds – detection of formation – isomerism in complexes-Historical
background of theories of metal complexes – Werner’s –Sidgwick and valence bond theories
Crystal field theory(CFT) – assumptions – splitting of d orbitals in different fields – CFSE
calculations – evidences for splitting factors affecting splitting –spectrochemical series – Jahn-
teller distortion – limitations of CFT Ligand Filed Theory (LFT) – sigma and pi bonding in
complexes – evidences for pi bonding – MO diagrams for Oh and Td complexes – effects of pi
donors and pi acceptors on splitting – nephelauxetic effect and series.

Unit-II Stability and reactions of complexes (15 hrs)

Stability of complexes kinetic and thermodynamic stabilities- formation constants – stepwise
and overall formation constants- factors affecting stability of the complexes -Kinetics and
mechanisms of ligand substitution reactions in Oh complexes- acid hydrolysis – base hydrolysis
- factors affecting the rate of reactions- anation reactions Substitution in SP complexes – trans
effect- theories of trans effect –applications Redox reactions of complexes – inner sphere and
outer sphere mechanisms- Marcus theory.

Unit-III Magnetic properties of metal complexes (15 hrs)

Basic definitions in magneto chemistry – thermal energy and magnetic properties- magnetism on
the basis of crystal field model .Zeeman effect – second order Zeeman effect on Sm(III)
Spin pairing – applications Anomalous magnetic moments – reasons -Co-operative magnetism –
antiferro magnetism – direct M- M interaction – super exchange – examples – Ferro magnetism
(Concept only)

Unit-IV Organometallics (15 hrs)

Types of organometallics – 18 e- rule –alkene complexes – Zeise’s salt – Hapticity Metal allyl
complexes – metal acetylene complexes -Metal sandwich complexes – Ferrocene – preparation
structure and reactivity-Reactions of organometallics – oxidative addition reductive elimination –
industrial applications of organometallics – Wilkinson’s catalysts- Reppe’s process- Oxo
process- Wacker’s process and Ziegler-Natta catalysts.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Metal Carbonyls and Nitrosyls (15 hrs)

Metal carbonyls – classification – description of M-CO bond- terminal and bridging CO groups –
carbonyls of V, Mn, Fe and Co. Metal carbonyl hydrides and metal carbonyl halides-Metal
nitrosyls - liner and bent nitrosyls- preparation and properties - nitrosyls of iron.

Text Books
I. James Huheey, Ellen A.Keiter and Richard L.Keiter, Inorganic Chemistry Principles of
Structure and Reactivity, Fourth edition, Pearson Education Asia, 2001.
II. Shriver and Atkins, Inorganic Chemistry, Third edition, Plenum Press, .
III. Wahid U.Malik, G.D.Tuli and R.D.Madan, Selected Topics in Inorganic Chemistry, First
Edition, S.Chand and Company Ltd., 1976 (Reprint 1998).
IV. R.Gopalan and V.Ramalingam,Concise Coordination Chemistry, First edition, Vikas
Publishing House Private Ltd., 2001 (Third reprint 2007).

Reference Books
1. F.Albert cotton, Advanced Inorganic Chemistry, Sixth edition, Geoffrey Wilkinson,
Carlos.A.Murilo and Manfred Bochmann, Wiley India, 2004 (Reprint 2008).
2. Gurdeep Raj,Advanced Inorganic Chemistry, Eleventh edition, Vol. II, Goel Publishing
House, 2008,
3. Agarwal and Keemti Lal, Advanced Inorganic Chemistry, Eleventh edition, Pragati
Prakashan, 2012.
4. J.D. Lee, Concise Inorganic Chemistry, Sixth edition, Wiley India Ltd., 2008.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Organic Transformations 4 0 0 4

Aim: To understand the mechanism of organic reactions

Objectives:
 To understand the mechanism of molecular rearrangements
 To acquire knowledge in natural products

Outcome:
 Students will acquire knowledge in mechanism of various organic reactions
 Learn about the preparation and uses of natural products

Unit-I Electrophilic Substitution Reactions (15 hrs)

Arenium ion mechanism -SE2 reaction (nitration, sulphonation, halogenation, Friedel-Crafts
alkylation, acylation), Vilsmeier-Hack formylation, substitution on monosubstituted benzenes –
orientation and reactivity – activation and deactivation (inductive effect, mesomeric effect),
examples of ortho & para directing groups, meta directing groups, activating and deactivating
substituent’s and their synthetic applications.

Unit-II Addition and elimination reactions (15 hrs)

Addition to double bonds: Addition of Halogens & Hydrogen Halides, Electrophilic addition to
alkynes, Nucleophilic addition to alkenes and alkynes, Nucleophilic addition to carbonyl
compounds-Hydride reduction-hemiacetals and acetals. E2 mechanism, direction of elimination
in E2, rate of E2 reactions, stereochemistry of E2 elimination, E2 elimination from acyclic systems
& cyclohexane systems, E1 mechanism, direction of elimination, E1 elimination from cyclic
compounds, Curtin-Hammett principle.

Unit-III Molecular rearrangements (15 hrs)

Pinacol-pinacolone, Wagner-meerwein, wolff, benzyl-benzilic acid, Beckmann, Hofmann,
Curtius, Lossen, Schmidt, Baeyer-Villiger, Hydroperoxide, Dakin, Favorskii, Stevens,
Sommelet-Hauser, Wittig, Neber, Fries, Claisen, dienone-phenol rearrangements and their
mechanisms.

Unit-IV Organometallic compounds (15 hrs)

Grignard reagents, organolithium, organocopper- Gilmans reagent, Gignard –copper- I reagent-
reactions of organo cuprates, epoxide cleavage, conjugate addition, Tandem-1,4-addtion,
organozinc-alkyl zinc iodides-di alkyl zinc-reformatsky reaction-cyclopropanation-Dibal-H
reduction, Julia olefinations, Petersons olefination.

Unit-V Alkaloids (15 hrs)

Occurrence-functions-nomenclature-classification-isolation-general structure determination-
synthesis and structural elucidation of quinine, papaverine, morphine.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. P.S. Kalsi, Organic Reactions and Their Mechanisms, Third edition, New Age
International Publishers, 2010.
II. V.K. Ahluwalia, R.K. Parashar, Organic Reaction Mechanisms, Third edition, Narosa
Publishing House, 2009.
III. W.Caruthers, Iain Coldhan, Modern Methods of Organic Synthesis, Cambrodge
university press,2015.
IV. I.L.Finar, Organic Chemistry Vol-II, Pearson Education, 2002.

Reference Book
1. Jerry March, Advanced Organic Chemistry: Reactions, Mechanisms and Structure, Wiley
Student Edition, 2006.
2. ROC.Norman and J.M coxon, Principles of organic synthesis Modern synthesis,CRC
press,1993
3. Francis. A Carey and Richard. J Sundberg, Advanced Organic Chemistry:Part-
B:Reaction and synthesis,Springer,2008

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

Thermodynamics and Quantum
II - 4 0 0 4
Chemistry

Aim: To understand the basics of Thermodynamics and quantum mechanics

Objectives:
 To understand the fundamentals and applications of statistical thermodynamics.
 To study the basics and applications of chemical thermodynamics.
 To study the fundamentals and applications of quantum chemistry.

Out Come:
 Students will get Knowledge about Various types of Quantum Statistics.

Unit-I Thermodynamics of open systems (15 hrs)

Partial molar properties, chemical potential, partial molar volume, partial molar heat content,
variation of chemical potential with temp. and pressure, fugacity, determination of fugacity,
variation with temp., and pressure. Thermodynamics of ideal and non-ideal solutions. Excess
functions for non-ideal solutions. Concepts of activity and activity coefficients, detn. of activity
and standard free energy, choice of standard states.

Unit-II Third law of thermodynamics & classical statistics (15 hrs)

Nernst heat theorem, need for third law, third law of TD’s, experimental verification of third law,
entropies of real gases, entropy changes in chemical reactions, Boltzmann entropy equation,
residual entropy, statistical meaning of third law. Introduction to statistical thermodynamics,
terminologies, Liouville’s theorem, statistical equilibrium, thermodynamic probability,
Boltzmann statistics, partition function, translational, rotational, vibrational and electronic
partition function, partition functions and thermodynamic functions (internal energy, heat
capacity, entropy, work function), partition function for monatomic and diatomic molecules,
limitations of Boltzmann’s statistics.

Unit-III Quantum statistics (15 hrs)

Bose-Einstein statistics, Bose-Einstein condensation, Fermi-Dirac statistics, Fermi energy, Fermi
energy of electron gas in a metal, thermionic emission, comparison between MB, FD & BE
statistics.

Unit-IV Basics of quantum mechanics (15 hrs)

Inadequacy of classical mechanics, black body radiation, photoelectric effect, Bohr’s quantum
theory, Davisson & Germar experiment, wave particle duality, Compton effect, De-broglie’s
equation, Uncertainty principle, theory of wave motion, Schrodinger’s equation for particle
waves, wave function and its physical meaning,Postulates of quantum mechanics, operator
algebra, Eigen values, Eigen functions, particle in a box (1-D and 3-D), quantum numbers, zero
point energy. Self Study (not for exams): Harmonic oscillators and rigid rotors.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Applications of quantum mechanics (15 hrs)

Approximation methods, perturbation and variation methods, application to hydrogen and helium
atom, R-S coupling and term symbols for atoms in the ground state, HFSCF theory, Slater
determinant, Born-Oppenheimer approximation, hydrogen molecule ion, hydrogen molecule,
Concept of hybridization, Huckel’s theory (ethylene, 1,3-butadiene and benzene).

Text Books
I. B.R. Puri, L.R. Sharma & Madan S. Pathania, Principles of Physical Chemistry, 42nd
edition, Vishal Publishing Company, 2008.
II. R.P. Rasthogi & R.R. Misra, An Introduction to Chemical Thermodynamics, Sixth
edition, Vikas Publishing House, 2008.
III. S.K. Sinha, Introduction to Statistical Mechanics, First edition, Narosa Publishing
House, 2005.
IV. R. K. Prasad, Quantum Chemistry, Third edition, , New Age International, 2007.
V. Gurdeep Raj, Advanced Physical Chemistry, 22nd edition, Goel Publications, 1998.

Reference Books
1. Donald A. Mcquarrie, John D. Simon, Physical Chemistry, First edition, Viva Books,
1998.
2. Peter Atkins, Julio de Paula, Physical Chemistry, Eighth edition, Oxford press, 2006.
3. Moudgil, The text book of Physical Chemistry, Printice hall publication, 2010.
4. Donaua.Mcquarrie, Qunatum Chemistry, Second Edition, University Science books
Publication, 2007.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Advanced Analytical Methods 4 0 0 4

Aim: To know about spectroscopy

Objective:
 To impart the knowledge of various advanced analytical techniques for chemical
characterization.

Outcome:
 The students will acquire knowledge of principles, instrumentation and applications of
separation techniques, AAS, inductively coupled plasma atomic emission spectroscopy,
NMR, XRD, fluorescence spectroscopy, and mass spectrometry.

Unit-I Separation techniques (15 hrs)

Capillary electrophoresis: Theory, instrumentation and applications. Ion Chromatography:
Theory, instrumentation, and applications.

Unit-II AAS & ICP (15 hrs)

Atomic Absorption Spectrometry: Introduction, basic principles, instrumentation, quantification
of elements, applications. Inductively coupled Plasma Atomic Emission Spectroscopy:
Introduction, physical and chemical principles, instrumentation, applications.

Unit-III NMR & XRD (15 hrs)

NMR: Theory, instrumentation, and applications. X-ray diffraction: Introduction, theory,
instrumentation and applications.

Unit-IV Fluorescence Spectroscopy & Microscopic Methods (15 hrs)

Theory, instrumentation and applications of Fluorescence spectroscopy. Principle,
instrumentation and applications of SEM and TEM techniques.

Unit-V Techniques of Mass Spectrometry (15 hrs)

Different ionization techniques, and detectors in mass spectrometers, basic instrumentation of
MS, and applications, GC-MS, LC-MS.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. Skoog, Holler, and Crouch, Instrumental Analysis, Brooks/Cole, 2007.
II. Willard, Merrit, Dean, Settle, Instrumental Methods of Analysis, Seventh edition, CBS
publishers and distributors, 1986.
III. Skoog, West, Holler, Analytical Chemistry: An Introduction, Sixth edition, Saunders
College Publishing, 1994.
IV. Khopkar, S.M., Basic Concepts of Analytical Chemistry, New Age International (P)
Limited, Publishers, (2008).

Reference Book
1. Frank Settle, Handbook of Instrumental Techniques for Analytical Chemistry, Pearson
education, 1997.
2. Silverstein, Bassler, Morrill, Spectrometric identification of organic compounds, John
Wiley & Sons, 1991.

17
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Inorganic Chemistry Laboratory 0 6 0 6

1. Separation and Analysis of an “Inorganic mixture containing two common and two less
common metal ions” including the following:
Common Ions: Pb, Cu , Bi, Cd, Al, Ni, Co, Mn, Zn, Ba, Ca, Sr and Mg; Less common
Ions: W, Se, Te, Mo, Ce, Th, Zr, Ti, V, U, and Li

2. Estimation of metals in a mixture (Volumetry and Gravimetry)

 Copper (V) - Nickel (G)
 Copper (G) – Zinc (V)
 Iron (V) – Nickel (G)
 Iron (V) – Magnesium (G)
3. Colorimetric Estimation of Cu,Cr,Fe,Ni and Mn

4. Preparation of any five of the following complexes:

i. Tetraamminecopper(II) sulphate,
ii. Potassium trioxalatochromate(III),
iii. Hexaureachromium(III) chloride,
iv. Sodium trioxalatoferrate(III),
v. Tris(acetylacetanato)copper(II),
vi. Tris(ethylenediamine)nickel(II) chloride

Reference Books
1. V.V. Ramanujam, Inorganic Semi-micro Analysis, 3rd edition, The National publishing
companay, 1997.
2. Gurdeep Raj, Pragathi Prakasan ,Advanced Inorganic Practical, Meerut.
3. Vogel’s Text book of Quantitative Analysis, Longman Group publishers, 5 th edition,
1994.
4. G.B.Kauffmann, Inorganic Coordination Compounds, Heyden and Son Ltd.
5. Burger,Synthesis of Inorganic Complexes, 1973.

Scheme of Evaluation

S.No. Particulars Max. marks

Analysis of the mixture
1 50
(Group separation-10, Analysis of each cation-10)
2 Preparation 30
3 Viva-voce 10
4 Record 10
Total 100

18
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Organic Chemistry Laboratory 0 6 0 6

1. Separation and Analysis of an organic binary mixture and derivatisation of the components.

2. Preparation of organic compounds (Any 8 from the following list): 1. Benzoic acid from
benzaldehyde, 2. Salicylic acid from methyl salicylate, 3. o-chlorobenzoic acid from anthranillic
acid, 4. Resacetophenone from resorcinol, 5. Para bromoacetanilide from acetanilide, 6. para-
nitroacetanilide from acetanilide, 7. Dibenzalacetone from acetone, 8. Benzhydrol from
benzophenone, 9. Phenylazo-2-naphthol from aniline, 10. Glucose penta acetate from glucose,
11. Piperidone from ethyl acetoacetate, 12. Naphthylmethyl ether from -naphthol

Reference Books
1. Jag Mohan, Organic, Analytical chemistry, theory and practice. Narose publishing
House, 2006.
2. Gnanaprakasam, Ramamurthy. Organic chemistry lab manual.

Scheme of Evaluation

S. No. Particulars Max. marks

Analysis of the mixture
1 50
(each component -25)
2 Preparation 20
3 Pilot separation 10
4 Viva-voce 10
5 Record 10
Total 100

19
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

II - Physical Chemistry Laboratory 0 6 0 6

Electrochemistry Experiments
Conductometry Experiments
1. Titration of : 1. Strong acid Vs strong base, 2. Weak acid Vs Strong base, 3. Weak acid
Vs weak base
2. Titration of a strong base Vs mixture of acids.
3. Precipitation titration: 1. BaCl2 Vs MgSO4, 2. AgNO3 Vs mixture of halides
4. Verification of Debye - Huckel – Onsager relation for a strong electrolyte
5. Dissociation constant of a weak electrolyte.
6. Solubility and solubility product of a sparingly soluble salt.

Potentiometry Experiments
1. Dissociation constant of a weak acid: titration method
2. Dissociation constant of a weak acid: Henderson method
3. Redox titration: KMnO4 Vs Fe2+ / KMnO4 Vs KI
4. Precipitation titration: AgNO3 Vs mixture of halides
5. Standard reduction potential of Cu / Zn / Ag electrode
6. Formal redox potential of Fe2+ / Fe3+ or Ce3+ / Ce4+ system
7. Solubility product of a sparingly soluble salt by (i) Single electrode method (ii)
Concentration cell method.

Non- Electrochemistry Experiments

1. Determination of partition coefficient of I2 between water and CCl4.
Equilibrium constant for the formation of I3- ion.
2. Construction of phase diagram for a pair of partially miscible liquids and the effect of
added impurity.
3. Construction of phase diagram for a three partially miscible liquids.
4. Construction of phase diagram for a simple eutectic system.
5. Construction of phase diagram for a system with compound formation
6. Determination mol.wt of a non-volatile solute by Rast’s method
7. Determination mol.wt of a non-volatile solute by transition temperature method
8. Study of adsorption of oxalic acid on charcoal. (Verification of Freundlich’s isotherm)
9. Determination of integral heat of solution by solubility method.
10. Determination of heat hydration of anhydrous CuSO4.
11. Determination of rate, order of the reaction between K2S2O8 and KI (clock reaction
method)
12. Verification of Bronsted –Bjerrum equation with reaction between K2S2O8 and KI.
13. Determination of order of the reaction for base hydrolysis of an ester- Condutomentric
method
14. Kinetics of acid catalyzed iodination of acetone – spectrophotometeric method.
15. Determination of Arrhenius parameters for acid catalyzed hydrolysis of ester.

20
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Reference Books
1. A.Finlay and J.A.Kitchener, Practical Physical Chemisty, Longman, 1973.
2. F.Daniels and J.H.Mathews Experimental Physical Chemistry, , Longman, 1985.
3. A.M.James, J.A.Churchil,Practical Physical Chemistry, 1961.
4. H.H.Willard, L.L.Merritt and J.A.Dean,Instrumental Methods of Analysis, Affiliated
East-West Press, 1965.
5. D.P.Shoemaker and C.W.Garland, Experimental Physical Chemistry, McGraw-Hill,
1974.

Scheme of Evaluation

S.No. Particulars Max.marks

1 Aim & Principle 5
2 Procedure, Formula, Model graph & Table 25
3 Reading & Calculation 30
4 Graph 10
5 Result 10
6 Record 10
7 Viva-voce 10
Total 100

21
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

Physical Methods in Inorganic
III - 4 0 0 4
Chemistry

Aim: To study about utility of spectroscopic techniques in study of inorganic compounds.

Objectives:
 To understand the role of spectroscopic methods in inorganic chemistry.
 To acquire basic knowledge about the application of spectral methods in structural
elucidation of inorganic compounds.

Outcome:
 Students will Understand the importance of various spectral methods in structural
elucidation of inorganic compounds

Unit-I Infra red & Raman spectroscopy (15 hrs)

Infrared spectroscopy: Principle – molecular vibrations – types- vibrational energy of a molecule
– Selection rules – dipole moments in the vibrating molecule –IR activity conditions -
anharmonicity of vibrations –consequences – expressions for fundamentals –overtones and hot
bands – coupling of rotations and vibrations. Normal mode analysis of C2V group (H2O , SO2
and ClO2) – ZXY2 type molecule – square planar XY4 complexes(AuCl4 ). Raman spectroscopy:
Raman effect – Raman ,Rayleigh and fluorescent scatterings –polarized Raman lines- conditions
for Raman activity. Structure of molecules from IR and Raman spectra – mutual exclusion
principle – violation of the principles – dynamic modes of molecules – structure determination -
identification of coordination – site symmetry lowering (SCN-, NO3- SO42- and Urea as ligands).

Unit-II Electronic spectra (15 hrs)

Free ion configurations –terms and states –spin orbit coupling –L-S coupling scheme –j-j
coupling scheme – terms for p2 and d2 configurations – hole formalism – energy of terms –
Hund’s rule – inter electronic repulsion parameters – spin –orbit coupling parameters.Effect of
crystal fields on terms – S, P, D and F terms – Ligand field term diagrams – Orgel diagrams –
expected electronic transitions – term interactions – Tanabe– Sugano diagrams – uses. Electronic
spectra of metal complexes – selection rules – group theoretical treatment of selection rules –
relaxation of selection rules – electronic spectra bands – band intensities and widths - Jahn-Teller
effect – spectrochemical series – nephelauxetic series – calculation of Dq, B’ and β – graphical
method – Konig’s numerical method – charge transfer spectra – spectra of lanthanides and
actinides.

Unit-III NMR spectroscopy (15 hrs)

Nuclear magnetic resonance – chemical shift-reference compounds –interpreting chemical shift –
spin –spin coupling. Aids in analyzing spectra-FTNMR-advantages- variable temperature NMR.
Dynamic NMR spectra –. symmetrical two -site exchange – (slow/fast)-barrier to internal
rotation-unsymmetrical site exchange – ring inversion – fluxional molecules –

22
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

13
fluorophosphoranes – organometallic compounds. NMR Spectra of other nuclei C,19F and 31
P
applications to simple molecules.

Unit-IV ESR spectroscopy (15 hrs)

Electron spin resonance- principle-ESR transition -selection rules-g-factor-presentation of
spectra-relaxation processes-hyperfine splitting-dipolar interaction-isotropic hyperfine
interaction-spin polarization-hyperfine splitting constants-anisotropy in A and g- factor –
dynamic processes-electron transfer-proton exchange-fluxional molecules. ESR of systems with
more than one unpaired electron Triplet state-spin transition in triplet state-effect of dipolar field
– zero field splitting- Kramer’s degeneracy-ESR of transition metal complexes-factors affecting
g-value-effect of John-Teller distortion-spectra of 3d series metal ions.

Unit-V Mossbauer, NQR & PES (15 hrs)

Mossbauer spectroscopy- Principle – Recoilless transition – Effect of Magnetic field –
Quadrupole nuclei – simple application to Iron and Tin complexes. Nuclear Quadrupole
Resonance Spectroscopy: Introduction-quadrupole moment – electrical field gradient-asymmetry
parameter- effect of external magnetic field-applications. Photo Electron Spectroscopy: UVPES
and XPES Koopmann’s theorem –ESCA - Auger effect- AES.

Text Books
I. K.Veera Reddy, Symmetry and spectroscopy of molecules, Second revised edition, New
Age International Publishers, 2009.
II. Russell.S.Drago, Physical Methods in Inorganic Chemistry, First edition, Affiliated East-
West Press Private Ltd., 1965.
III. D.N.Sathyanarayana, Introduction to Magnetic Resonance Spectroscopy ESR, NMR,
NQR, First edition, I. K. International Publishing House Pvt. Ltd., 2009.
IV. C.N.Banwell & Elaine McCash, Tata, Fundamentals of Molecular Spectroscopy, Fourth
edition, McGraw- Hill Publishing Co.Ltd., 1994.

Reference Book
1. D.N.Sathyanarayana, Electronic Absorption Spectroscopy and Related Techniques, First
edition, Universities Press (India) Ltd., 2001.
2. E.A.V.Ebsworth,David, W.H.Rankin, Structural Methods in Inorganic Chemistry, ELBS
edition, Stephen Cradock, Blackwell Scientific Publications, 1988.
3. D.N.Sathyanarayana, , Vibrational Spectroscopy Theory and Applications, Second
edition, New Age International Publishers 2004 (Reprint 2007).

23
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Organic Spectroscopy 4 0 0 4

Aim:
 To study the principles and applications of spectroscopic methods in structural
elucidation of simple organic molecules

Objective:
 To impart the knowledge of structure elucidation of organic compounds using
spectroscopic data.

Outcome:
 The students will acquire knowledge of using UV-Visible, IR, NMR and Mass spectral
data for elucidating the structure of organic compounds.

Unit-I UV-Vis spectroscopy (15 hrs)

Electronic transitions, red shift, blue shift – effects of solvents, calculation of λmax for isolated
double bonds, conjugated double bonds, polyenes, carbonyl compounds (Woodward-Fieser
rules), aromatic systems. Spectral problems.

Unit-II Infra Red spectroscopy (15 hrs)

Absorption of IR radiation, Molecular vibrations (Vibrational motion is quantized, dipole
moment and IR spectra, fundamental vibrations, symmetry and IR spectra, Overtones and
combination bands, coupled vibrations, Fermi resonance), calculation of vibrational frequencies,
Interpretation of IR spectra of alkanes, alkenes, alkynes, aromatic rings, alcohols, phenols,
ethers, carbonyl compounds, aldehydes, ketones, carboxylic acids, esters, amides, acid chlorides,
amines, nitro compounds. Spectral problems.

Unit-III H1NMR & C13NMR spectroscopy (15 hrs)

Introduction-chemical shift-TMS scale-spectrum-shielding effect and spin-spin splitting-theory
of PMR-internal standard-factors affecting chemical shift-equivalent and non-equivalent protons-
theory of spin-spin splitting-magnitude of coupling constant- 2D NMR – ROESY- COSY -
NOE- NOESY-DOSY. Spectral problems. Introduction-spectrum-operating frequency-off
resonance decoupling-chemical shift equivalence-chemical shifts. Spectral problems.

Unit-IV Mass spectrometry (15 hrs)

Introduction-EI ionization method-base peak-molecular ion peak-instrumentation-fragmentation
pattern of general and simple organic molecules and derivatives.

24
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Combined spectral problems (15 hrs)

Combined spectral problems.

Text Books
I. P.S. Kalsi, Spectroscopy of Organic Compounds, Fifth edition, New Age International
Publishers, 2004.
II. Pavia, Lampman, Kriz, Vyvyan, Spectroscopy, Brooks/Cole, 2007.

Reference Book
1 . Silverstein, Bassler, Morrill, Spectrometric identification of organic compounds, John
Wiley & Sons, 1991.
2 . William Kemp, Organic Spectroscopy, Palgrave, 1991.

25
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Electrochemistry and Spectroscopy 4 0 0 4

Aim: To understand the physical principles behind various spectral methods

Objectives:
 To study about the various theories of Electrolytic Conductance & Irreversible Electrode
process.
 To study in detail Raman and electronic spectroscopies.
 To study in detail NMR and ESR spectroscopies.

Outcome:
 Students acquire Knowledge about Principles of Spectroscopy & about Irreversible
electrode process

Unit-I Theory of Electrolytic Conductance (15 hrs)

Degree of dissociation, ionic atmosphere, Debye-Huckel theory, mechanism of electrolytic
conductance, DHO equation, validity of DHO eqn., deviations from DHO eqn., significance of
degree of dissociation, determination of degree of dissociation, conductance ratio and DHO,
Debye-Falkenhagen and Wien effects. Debye-Huckel limiting law, Debye-Huckel Bronsted
equation, test for DH limiting eqn, extension of DH theory, triple ions (concept only).

Unit-II Electrified Interface (15 hrs)

Thermodynamics of electrified interface, Lippmann equation, electro-capillary curves, surface
excess, determination of surface excess, structure of electrical double layer, Helmholtz-Perrin
model, Gouy-Chapman model, Stern model. Electro-kinetic Phenomena, Zeta potential, electro-
osmosis, streaming potential, electrophoresis, determination of zeta potential, effect of ions on
electro-kinetic phenomena.

Unit-III Irreversible electrode processes & Electrodics (15 hrs)

Theories of overvoltage and its determination, factors affecting overvoltage, exchange current
density, polarization.Irreversible electrode processes, polarography, theory and experimental set
up, Ilkovic equation derivation, Halfwave potential, applications of polarography, amperometric
titrations, kinetics of electrode reactions, Butler-Volmer equation derivation, Tafel equation,
transfer coefficient (concept only).

Unit-IV Physical principles of spectroscopy, IR & Raman spectra (15 hrs)

EM radiation, quantization of energy, regions of spectrum, interaction of radiation with matter,
representation of spectra, spectrometers, signal to noise ratio, resolving power, parameters for a
spectral line (position, intensity, width), factors affecting them, FT spectroscopy, computer
averaging.Infra red spectroscopy, the vibrating diatomic molecule, simple harmonic oscillator
model, the anharmonic oscillator, diatomic vibrating rotator, break down of Born-Oppenheimer
26
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

approximation, vibrations of polyatomic molecules, overtones and combination frequencies,

influence of rotation on the spectra of polyatomics, parallel and perpendicular vibrations, skeletal
vibrations and group frequencies. Raman effect, classical and quantum theories, rotational
raman spectra, symmetric tops and asymmetric tops, vibrational raman spectra, role of mutual
exclusion, polarization of light and raman effect, combined use of raman and IR.

Unit-V Electronic and Spin Resonance Spectroscopies (15 hrs)

Electronic spectroscopy of molecules, Born-Oppenheimer approximation, vibrational coarse
structure, progressions and sequences, Frank-Condon principle, dissociation energy, rotational
fine structure, Fortrat diagram, pre-dissociation. NMR Spectroscopy: Interaction of spin and
applied field, population of energy levels, Larmor precision, relaxation, FTNMR, multiple pulse
FTNMR, NMR spectrum of hydrogen nuclei, chemical shift, coupling constant, Quadrupole
effect. ESR Spectroscopy: Position of ESR absorption, hyperfine structure, fine structure of ESR
spectrum, zero filed splitting, calculation of electron density.

Text Books
I. Samuel Glasstone, An Introduction to Electrochemistry, First edition, Affiliated East
West Press Private Ltd., 1942, reprint 1999.
II. J. N. Gurtu & A. Gurtu, Pragati Prakashan, Advanced Physical Chemistry, Eighth
revised edition, 2006.
III. B.R. Puri, L.R. Sharma & Madan S. Pathania, Principles of Physical Chemistry, 37th
edition, Shoban Lal Nagin Chand and Co., 1998.
IV. C. N. Banwell & Elaine McCash, Fundamentals of Molecular Spectroscopy, Fourth
edition, Tata McGraw-Hill Publishing Co. Ltd., 1994, reprint 2001.

Reference Books
1. Skoog, Holler, and Crouch, Instrumental Analysis, Brooks/Cole, 2007.
2. H. Kaur, Pragati Prakashan, Instrumental Methods of Chemical Analysis, Sixth edition,
2010.
3. John.O.M Bockris and Amulya K.N Reddy, Modern Electrochemistry, Vol 1&2 ,Springer
publications, 2008.
4. O.D. Tyagi & M. Yadav, A Text book of Spectroscopy, Anmol publications, 2002.

27
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Organic Reagents & Reactions 4 0 0 4

Aim: To enable the students to learn the principles of Photo chemical reactions and reagents
used for various reactions

Objective:
 To impart the knowledge of Oxidation-reduction reactions are widely used to produce
chemicals that are used in manufacturing

Outcome:
 Students get knowledge about organic compounds through the name reactions, oxidation
and reduction reactions.
 To get an idea about terpenoids.

Unit-I Oxidation reactions (15 hrs)

Mn(VII) oxidants: for the oxidation of alcohols, alkenes, alkynes, aromatic side chains and rings,
aldehydes, ketones, amines, nitro, and carbonyl compounds. Oxidation by MnO2. Cr (VI)
oxidants: for the oxidation of alcohols, phenols- Jones reagent, Chromium trioxide-pyridine
complex, pyridinium chlorochromate complex, pyridinium dichromate, Oxidation of alkanes,
alkenes, and aromatic side chains and nucleus-catalytic asymmetric epoxidation, Swern
oxidation,

Unit-II Reduction reactions (15 hrs)

Reduction using: Copper Chromite, LiAlH4, Sodium borohydride, Sodium cyanoborohydride,
Diborane, asymmetric reductions using Borane complexes Sodium/alcohol, Sodium/liq. NH3,
Magnesium, Zinc Chloride acid, Hydazine, Di-amide, Formic acid, silanes, stannous chloride,
Sn/HCl, Zn/CH3COOH, Zn/NaOH, Sodium metabisulphite, Sodium dithionite, Mg/alcoho,l.

Unit-III Organic name reactions (15 hrs)

Aldol condensation, Diels Alder reaction, Enamine reaction, Elbs persulfate oxidation, HVZ
reaction, Perkin reaction, Riemer-Tiemann reaction, Rosenmund reaction, Wurtz reaction,
Shapiro reaction, Robinson annulations, Chichibabin amination, MPV reduction.

Unit-IV Photochemical reactions (15 hrs)

Laws of photochemistry, electronic excitation, excited states, chemistry of excited molecules,
difference between photochemical and thermal reactions, photochemical reactions of carbonyl
compounds and olefins, photoisomerization of cis-trans stilbenes, photochemical cycloaddition
reactions.

Unit-V Terpenoids (15 hrs)

Nomenclature-properties-isolation-isoprene rule-special isoprene rule-gem dialkyl rule-
classification-general methods for structure determination-synthesis and structural determination
of α pinene-camphor.
28
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. V.K. Ahluwalia, R.K. Parashar, Organic Reaction Mechanisms, Third edition, Narosa
Publishing House, 2009.
II. P.S. Kalsi, Organic reactions and their mechanisms, Third edition, New Age
International Publishers, 2010.
III. Gurdeep R. Chatwal, Organic Chemistry of Natural Products, Vol-I, Fifth edition,
Himalaya Publishing Company, 2011.
IV. Gurdeep R. Chatwal, Organic Chemistry of Natural Products, Vol-II, Fifth edition,
Himalaya Publishing Company, 2011.

Reference Book
1. I.L. Finar, Organic Chemistry, Vol I and II, Longman, 1963.
2. F.A. Cary and R.I. Sundberg Advanced Organic Chemistry, Part A & B, 5th Ed.,
Springer, 2009.
3. Laszlo Kurti, Barbara Czako, Strategic Applications of Named reactions in Organic
Synthesis, Elsevier Academic press,2005.

29
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Green Chemistry 4 0 0 4

Aim: To make the students to understand, appreciate the practices and outcomes of green
chemistry.

Objectives:
 To define “green chemistry” and place its birth and expansion in an historical context.
 To introduce the principles of green chemistry, outline examples, and establish the
arguments for our need to recognize green criteria in the practice of chemistry.
 To present examples of successful green technologies.
Outcome:
 A functional understanding of the field of green chemistry.
 A working understanding of the twelve principles of green chemistry.
 An understanding of several real world examples where organizations used green
chemistry to improve the sustainability performance of their products.
 An appreciation of how the practice of green chemistry enhances competitiveness,
innovation and faster time to market.

Unit-I Principles & Concept of green chemistry (15 Hours)

Introduction –Concept and Principles-development of Green Chemistry- Atom economy reactions
–rearrangement reactions , addition reactions- atom uneconomic-sublimation elimination-Wittig
reactions-toxicity measures- Need of Green Chemistry in our day to day life.

Unit-II Green Metrics - Measuring environmental performance (15 Hours)

Importance of measurement – lactic acid production-safer Gasoline – introduction to life cycle
assessment-four stages of Life Cycle Assessment (LCA) –Carbon foot printing-green process
Matrics-eco labels -Integrated Pollution and Prevention and Control(IPPC)-REACH
(Registration, Evaluation, Authorization of Chemicals)

Unit-III Emerging green technology and alternative energy sources (15 Hours)
Design for Energy efficiency-Photochemical reactions- Advantages-Challenge faced by
photochemical process. Microwave technology on Chemistry- Microwave heating –Microwave
assisted reactions-Sono chemistry and Green Chemistry –Electrochemical Synthesis-Examples of
Electrochemical synthesis- Organic solvents – effects of solvents – Solvent less synthesis.

Unit-IV Renewable resources (15 Hours)

Biomass –Renewable energy – Fossil fuels-Energy from Biomass-Solar Power- Other forms of
renewable energy-Fuel Cells-Alternative economics-Syngas economy- hydrogen economy-Bio
refinery chemicals from fatty acids-Polymer from Renewable Resources –Some other natural
chemical resources.

30
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Unit-V Industrial case studies (15 Hours)

Methyl Methacrylate (MMA)-Greening of Acetic acid manufacture-Vitamin C-Leather
manufacture –Types of Leather –Difference between Hide and Skin-Tanning –Reverse tanning –
Vegetable tanning –Chrome tanning-Fat liquoring –Dyeing –Application-Polyethylene- Ziegler
Natta Catalysis-Metallocene Catalysis-Eco friendly Pesticides-Insecticides.

Text Books
I. Lancaster, M. Green Chemistry: An Introductory Text; The Royal Society of Chemistry:
2002.
II. Anastas, P. T.; Warner, J. C. Green Chemistry: Theory and Practice; Oxford University
Press,1998.
III. Manahan, S. E. Green Chemistry and the Ten Commandments of Sustainability;
ChemChar Research Inc, 2005.
IV. J. Clark, D. Macquarrie, “Handbook of Green Chemistry & Technology”, Blackwell
Science, 2002.
V. Ahluwalia, V. K.; Kidwai, M. New Trends in Green Chemistry; Kluwer
Academic:Dordrecht, The Netherlands, 2004.

Reference Books
1. Sheldon, R. A.; Arends, I.; Hanefeld, U. Green Chemistry and Catalysis; Wiley-VCH:
Weinheim, 2007.
2. Renewable Resources: Scope and Modificaiton for Non-Food Applications; Stevens, C.
Verhé, R. G., Eds.; John Wiley & Sons Ltd.: West Sussex, 2004.
3. Tundo, P.; Perosa, A.; Zecchini Methods and Reagents for Green Chemistry: An
Introduction;, F., Eds.; John Wiley & Sons, Inc.: Hoboken, NJ, 2007.

31
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Polymer Chemistry 4 0 0 4

Aim: To understand the basic concepts of polymers

Objectives:
 To gain the knowledge in the preparation, properties, characterization and Uses of
polymers.
 To Understand the industrial polymer processing techniques

Outcome:
 Students get knowledge about the various polymerization techniques.
 Learn about the applications of industrial oriented polymers.

Unit-I Basic concepts of polymers (15 hrs)

Importance of polymers - Monomers - Degree of polymerization – Linear - Branched and
Network polymers - Classification of polymers –Polymerization Methods: Condensation,
Addition - Radical chain - Ionic and Co-ordination and Co-polymerization-Polymerization
conditions and reactions- Polymerization in homogeneous and heterogeneous systems.

Unit-II Kinetics and Mechanisms (15 hrs)

Kinetics and mechanisms of Condensation, Addition - Radical chain - Ionic and Co-ordination-
(Ziegler-Natta) polymerization and Co-polymerization.

Unit-III Polymer characterization (15 hrs)

Chemical analysis of polymers - Spectroscopic methods - X-ray diffraction studies - Thermal
analysis - Physical testing: Tensile strength – Fatigue – Impact - Tear resistance - Hardness and
Abrasion resistance. Polydispersion - Molecular weight: Number, Weight and Viscosity average
molecular weights - Polydispersity and molecular weight distribution - Practical significance of
molecular weight - Measurement of molecular-weights: End-group, Viscosity, Light scattering,
Osmotic and Ultracentrifugation methods.

Unit-IV Polymer Structure and properties (15 hrs)

Molecular forces in polymers - dipole forces, induction forces, dispersion forces, Dependence of
physical properties on intermolecular forces. Configuration of polymer chains – Crystal structure
of polymers – morphology of crystalline polymers – structural requirements for crystallinity,
degree of crystallinity, crystallizability-mechanism of crystallization– Crystalline melting point –
glass transition temperature.

Unit-V Synthesis, Applications and polymer processing (15 hrs)

PE, PS, PMMA, PVA and PTFE -Polymer Processing: Molding – Compression – Injection –
Blow – Thermoset – Extrusion – Brief Notes on Recent Advances in Polymers: Conducting
Polymers - Polyaniline – Bio-degradable polymers –Polymer composites.

32
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. F.W. Billmeyer Jr., Wiley-India Textbook of Polymers Science, Second Edition, Wiley-
India, 2007.
II. V.R. Gowarikar, N.V. Viswanathan, Jayadev Sreedhar, Polymer Science, First edition,
New Age International (P) Ltd., Publishers, Reprint 2005.
III. Introduction to Polymer Chemistry, Charles E. Carraher. Jr., CRC Press, Taylor and
Francis, 2006

Reference Books
1. M.S. Bhatnagar, A Text book of Polymer chemistry, S.Chand Publications, 2004.
2. B.K. Sharma, polymer Chemistry, Goel Publishing House, 2014
3. The Elements of Polymer Science and Engineering, Alfred Rudin, Elsevier Academic
Press, 1999.
4. Polymer Science and Technology, Premamoy Ghosh, Tata MC Graw Hill, 2011.

33
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Nanomaterials 4 0 0 4

Aim: To study about nanoscience and nanotechnology

Objectives:
 To understand the basic concepts and chemistry of nanomaterials
 To familiarize with importance and applications of nanotechnology

Outcome:
 Students acquire basic knowledge on nanoscience
 They get an idea about the scope and importance of nanotechnology.

Unit-I Introduction to Nanoscience (15 hrs)

The Science of Nano - Atomic structures - Molecular and atomic size - Bohr radius – Emergence
of Nanotechnology – Differences between bulk and nanomaterials – Reasons - Challenges in
Nanotechnology.

Unit-II Growth of Nanomaterials (15 hrs)

Influence of nucleation - rate on the size of the crystals - macroscopic to microscopic crystals
and nanocrystals - large surface to volume ratio, top-down and bottom-up approaches - self
assembly process – template assisted and template free approach – micelles assisted methods -
grain boundary volume in nanocrystals - defects in nanocrystals - surface effects on the
properties.

Unit-III Types of Nanostructures (15 hrs)

Different types of nanomaterials - Types of Nanocrystals - One Dimensional (1D) - Two
Dimensional (2D) -Three Dimensional (3D) nanostructured materials - Quantum dots - Quantum
wire - Core/Shell nanostructures - Synthesis and properties of Carbon Nanotubes (CNT) and
Graphene – Metal nanostructures of Au and Ag - Metal oxides (TiO2, CeO2, ZnO) -
Semiconductors (Si, Ge, CdS, ZnSe) - Ceramics and Composites – Polymer nanocomposites.

Unit-IV Instrumentation Analysis for Nanomaterials (15 hrs)

Principle, Theory, Working and Applications of X-Ray Diffraction, Scanning Electron
Microscopy, Transmission Electron Microscopy, High Resolution Transmission Electron
Microscopy, Field Emission Scanning Electron Microscopy, Atomic Force Microscopy.

Unit-V Applications of Nanoscience and Nanotechnology (15 hrs)

Biological applications - Biochemical sensor - Nanoscience in Drug Delivery - Nanomedical
applications of green nanotechnology - Membrane based water purification. Energy applications
– Electrocatalysis – Nano Electronics and Nano Optics – Industrial Applications.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text books:

I. A.K.Bandyopadhyay, Nano Materials, New Age International, India, 2008.

II. K.K.Chattopadhyay, A.N.Banerjee Introduction to nanoscience & nanotechnology, PHI
India, 2009.
III. T.Pradeep, Nano: the essentials understanding nanoscience & nanotechnology, Mcgraw-
Hill Education India Pvt. Ltd, 2007.
IV. C.Carl, Koch, Nanostructured materials: Processing, properties & applications, William
Andrew, NY, 2007.

Reference books:
1. M. Wilson, K. Kannangara, G Smith, M. Simmons, B. Raguse, Nanotechnology: Basic
science and Emerging technologies, Overseas Press India Pvt Ltd, New Delhi, First
Edition, 2005.
2. C.N.R. Rao, A. Muller, A. K. Cheetham (Eds), The chemistry of nanomaterials: Synthesis,
properties and applications, Wiley VCH Verlag Gmbh&Co, Weinheim, 2004.
3. Kenneth J. Klabunde (Eds), Nanoscale Materials Science, John Wiley & Sons, InC, 2001.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

III - Analytical Chemistry Laboratory 0 6 0 6

1. Estimation of KMnO4 by Visible Spectrophotometery.

2. Estimation of Dye by Visible Spectrophotometery.
3. Estimation of Surfactant by UV-Visible Spectrophotometery.
4. Determination of Kinetics by UV-Visible Spectrophotometery.
5. Qualitative analysis of organics by FT-IR Spectrometer – KBr – technique.
6. Qualitative analysis of organics by FT-IR Spectrometer – ATR-technique.
7. Pot. Ferri cyanide and Ferro cyanide by Cyclic Voltammetry.
8. Electrochemical Oxidation of Organics by Cyclic Voltammetry.
9. Estimation of Fluorescence Dye by Spectrofluorometer.
10. Estimation of Quantum Yield by Spectrofluorometer.
11. Estimation of Alkali metals by Flame Photometry.
12. Determination of Reaction Kinetics by FT-IR spectrometer.
13. Analysis of water quality parameters.
14. Estimation of COD of waste water by spectrophotometer.

Reference Book
1. Course material developed by the department of chemistry, SCSVMV.

Scheme of Evaluation

S. No Particulars Max. Marks

Aim, Principle, Procedure, Model graph
1 20
and Table
2 Graph 10
3 Calculation 10
4 Interpretation of result 10
5 Spectra Interpretation 30
6 Record 10
7 Viva-voce 10
Total 100

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Soft Skills and Scientific Writing 4 0 0 4

Aim: To develop soft skills of students and to introduce about scientific literature to the students.

Objective:
 To impart the knowledge of soft skills, scientific literature survey and report writing.

Outcome:
 The students will acquire knowledge of time management, positive thinking and report
writing

Unit-I Memory and study skills (15 hrs)

Definition and importance of memory-Causes of forgetting-How to forget (thought stopping),
how to remember (techniques for improving memory)-The technique of passing exams-
management of examination fear.

Unit-II Power of positive thinking (15 hrs)

Nurturing creativity, decision-making and problem solving-Thinking power- seven steps for
dealing with doubt-Traits of positive thinkers and high achievers-Goals and techniques for
positive thinking-Enhancement of concentration through positive thinking-Practicing a positive
life style-Advantages of time management.

Unit-III Literature survey (15 hrs)

Chemical nomenclature and literature primary sources - secondary sources including reviews.
Treatise and monographs, literature searching, Review of work relevant to the chosen problems.
Abstraction of a research paper.

Unit- IV Writing a thesis or paper (15 hrs)

General format - page and chapter formation. The use of quotation - footnotes - tables and
figures - referencing - appendixes - revising the paper or thesis - editing and evaluating the final
product - proof reading the final typed copy - Publication of Research paper

Unit-V Oral presentation skills (15 hrs)

Structure, voice, appearance, body language – delivery Presentation a scientific seminar –
appearing in interviews.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. G.A. Dudley, Double your learning power,Thomas Publishing Group Ltd., Delhi, 2004.
II. J. Anderson, B.H. Dursten and M. Poole, Thesis and Assignment Writing, Wiley Eastern,
1977.
Reference Books
1. D.J. Mile, Power of positive thinking, Rohan Book Company, Delhi, 2004.
2. H. Lorayne, How to develop a super power memory, Thomas Publishing Group Ltd.,
2004.
3. J. Anderson, B.H. Dursten and M. Poole, Thesis and Assignment Writing, Wiley Eastern,
1977.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Surface Chemistry and Photo Chemistry 4 0 0 4

Aim:
 To make the students to understand about the basics of surface chemistry and
Photochemistry.

Objectives:
 To understand the concepts and applications of surface chemistry.
 To study about Photophysical Processes & Principles of PhotoChemistry

OutCome:
 Students acquire the knowledge about Catalytic reactions Which are used in day to day
life.

Unit-I Adsorption (15 hrs)

Gas-Solid interface, types of adsorption, factors affecting adsorption, physical adsorption,
adsorption isotherms, Freundlich’s adsorption isotherm, Langmuir adsorption isotherm, BET
equation, modification of BET equation, determination of surface area, Harkins and Jura method,
Benton and White method, point B method, importance of surface area, heat of adsorption.
Adsorption from solutions, types, Gibbs adsorption equation, verification of Gibbs equation,
Domain & Barker method, tracer method, surface tension and surface free energy, capillary
condensation, wetting phenomena, applications of adsorption.

Unit-II Reaction on Surfaces (15 hrs)

Mechanisms of surface reactions, effect of surface heterogeneity, unimolecular surface reactions,
bi-molecular surface reactions, combination and formation of atoms at surfaces, exchange
reactions, transition state theory of surface reactions, comparison of homogeneous and
heterogeneous reaction rates. Classification of catalytic reactions, types of catalysts, metals,
semi-conductors, insulators, energetic of adsorption processes.

Unit-III Colloids (15 hrs)

Emulsions, types, characteristics of emulsions, emulsifiers, theories of emulsification,
importance of emulsion, micellar emulsion, applications, micelles, structure of micelles, ionic
micelles, CMC, determination of CMC, solubilization, Donnan membrane equilibrium and its
application. Applications of colloids.

Unit-IV Excitation of Molecules (15 hrs)

Mechanism of radiation absorption, electric dipole transitions, Einstein’s treatment, intensity of
electronic transitions, selection rules, directional nature of light absorption, life times of excited
states, types of transitions, two photon absorption spectroscopy. Physical properties of excited
molecules, changes on electronic excitation, potential energy diagram, shape of absorption band
and Frank-Condon principle, emission spectra, environmental effect, dipole moment, acidity

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

constant, redox potential in excited states, geometry of electronically excited molecule, flash
photolysis.

Unit-V Photophysical Processes (15 hrs)

Types of Photophysical pathways, Jablonski diagram, radiationless transition, internal
conversion, intersystem crossing, fluorescence, phosphorescence, emission property and
electronic configuration, kinetics of unimolecular processes, state diagram, delayed fluorescence,
effect of temperature on emission processes. Kinetic collisions and optical collisions, mechanism
of fluorescence quenching in gases, collisions in solution, Stern-Volmer equation, concentration
dependence of quenching, excimer formation. Quenching by foreign substances,
photosensitization, charge transfer mechanisms, energy transfer mechanism, donor acceptor
interaction in energy transfer (qualitative treatment), sensitized delayed emission.

Text Books
I. Gurdeep Raj, Advanced Physical Chemistry, 22nd edition, Goel Publications, 1998.
II. Keith J. Laidler, Chemical Kinetics, Third Edition, Pearson Education, 2004.
III. J. Rajaram, J.C. Kuriacose, Kinetics and Mechanisms of Chemical Transformations,
First edition, Macmillan, 1993, reprint 2011.
IV. K.K. Rohatgi-Mukherjee, Fundamentals of Photochemistry, New Age International
Publishers, 1978, revised edition 2002.

Reference Book
1. Peter Atkins, Julio de Paula, Physical Chemistry, Eighth edition, Oxford press, 2006.
2. Arthur W.Adamson & Aulice P. Gast, Physical Chemistry of Surface, Wiley India Pvt
Ltd., 2012.
3. Gurudeep Raj, photochemistry, Krishna Prakashan publications,2012.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Synthetic Organic Chemistry 4 0 0 4

Aim: To teach the synthetic organic methodologies and reagents in organic synthesis

Objective:
 To impart the knowledge of multistep organic synthesis.

Outcome:
 Students get knowledge about the chemical modification of a functional group to obtain
chemoselectivity in a subsequent chemical reaction.
 To get an idea about modern synthesis.

Unit-I Heterocyclic compounds (15 hrs)

Chemistry of heterocyclic compounds, synthesis and reactivity of the following systems-
quinoline, isoquinoline, benzofuran, benzothiophene, pyrazole, imidazole, oxazole, isoxazole,
thiazole, isothiazole, pyridazine, pyrimidine, and pyrazine.

Unit-II Protecting groups and retero synthetic analysis (15 hrs)

Requirements for protecting groups-Protection and deprotection of hydroxyl, carboxyl, carbonyl,
carboxy amino groups and carbon-carbon multiple bond; chemo- and regioselective protection
and deprotection; illustration of protection and deprotection in synthesis.
Disconnection approach to synthesis – disconnection- definition – preferred positions – FGI –
Synthons – synthetic equivalents – reterosynthetic analysis of Benzocaine, BHT and saccharine.
Types of disconnections – order of disconnections - one group disconnections – RCO-X and
ROH disconnections – two group C-X disconnections – types and examples only.

Unit-III Reagents in organic synthesis (15 hrs)

Preparation and reactions of: Aluminium isopropoxide, NBS, Diazomethane, DDQ, DCC, LTA,
LAH, OsO4, Sodium borohydride, Wittig reagent-hydroboration-oxidation-regio and stereo
selectivity.

Unit-IV Modern synthetic methods (15 hrs)

Baylis-Hillman reaction, Henry reaction, Nef reaction, Kulinkovich reaction, Ritter reaction,
Sakurai reaction, Tishchenko reaction and Ugi reaction. Brook rearrangement; Tebbe olefination.
Metal mediated C-C and C-X coupling reactions: Heck, Stile, Suzuki, Negishi and Sonogashira.

Unit-V Pericyclic reactions (15 hrs)

Types of Pericyclic reactions, stereochemistry of Pericyclic reactions, M.O. theory, symmetry
properties of reactant and product orbitals, 2+2 cycloadditions, 4+2 cycloadditions, cyclization
of 4n systems, 4n+2 systems, correlation diagram, sigmatropic rearrangements.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. V.K. Ahluwalia, R.K. Parashar, Organic Reaction Mechanisms, Third edition, Narosa
Publishing House, 2009.
II. P.S. Kalsi, Organic reactions and their mechanisms, Third edition, New Age
International Publishers, 2010.
III. F.A. Carey and R.I. Sundberg., Advanced Organic Chemistry, Part A & B, 5th Ed.,
Springer, 2009.

Reference Book
1. Jerry March., Advanced Organic Chemistry: Reactions, Mechanisms and Structure,Wiley
Student Edition, 2006.
2. R.O.C. Norman and James.M. Coxon, Principles of Organic Synthesis, Modern
synthesis,CRC press,1993
3. S.Warren,The Disconnection Approach, John Wiley & Sons, 2004.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Nuclear and Bioinorganic Chemistry 4 0 0 4

Aim: To study about basic concepts of nuclear chemistry and bioinorganic Chemistry

Objectives:
 To understand the basic concepts of nuclear reactions and nuclear reactor.
 To understand the biological importance of inorganic chemistry.

Outcome:
 Students will get an idea nuclear reactions and applications of inorganic compounds in
biological systems.

Unit-I Structure of nucleus (15 hrs)

size and shape of nucleus – nuclear stability - nuclear angular momentum – magnetic properties
of nuclei – quadrupole moment –nuclear parity-forces and interactions.
Nuclear models: Shell, liquid drop and Fermi gas models – collective model –optical model.
Detection and measurement of radioactivity: Radio activity – units of radio activity -
characteristics of decay – decay kinetics – theories of alpha and beta decay(primitive treatment
only) – gamma emission – artificial radio activity – detectors –ionization chamber scintillation
and – semiconductor detectors.

Unit-II Nuclear reactions and applications (15 hrs)

Nuclear reactions: Bethe’s notation – types of reactions –cross section- compounds nuclear
theory – photo and thermo nuclear reactions – fusion reactors – origin and evolution of elements.
Applications of radioactivity: Nuclear reactors – breeder reactor –India’s nuclear energy –
recovery of U and Pu from spent fuel – applications of radio isotopes – probing – Szilard-
Chalmers’ reaction – cow and milk systems –tracers. Elementary particles of nucleus:
classification – particles and antiparticles – Parton structure –Quarks and Gluons – classification
of Quarks – Higgs Boson.

Unit-III Bioinorganic Chemistry (15 hrs)

Metal ions in biological systems: Electron transfer systems –cytochrome and Fe –S proteins -
Structure and functions -Transport and storage of oxygen – Haemoglobin –structure and
functions –cyanide poisoning –Myoglobin-Chlorophyll – Cyanocobalamine- structure and
functions- Calcium in biological systems –sodium-potassium ion pumps-Metals in medicine – Pt
binding to DNA.

Unit-IV Acids, Bases and Non-Aqueous Solvents (15 hrs)

Acids and Bases: Arrhenius theory –Bronsted –Lowry theory –Lux-Flood definition – Solvent
system definition – Lewis concept – Usanovich definition – generalized acid base concept -
HSAB concept – basis of classifications – applications – pi bonding contributions –electro
negativity and hard soft species – limitations of the principle. Non aqueous solvents:

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

classification of solvents – leveling and differentiating solvents ionizing solvents –Liq.NH3 –

Liq.SO2 - Liq.N2O4 - Liq. BrF3 – acetic acid.

Unit-V Inorganic nomenclature and redox stability (15 hrs)

Affixes used in naming- general naming – names of ions- radicals –acids – salts and salt like
compounds- boron hydrides-isopolyanions and heteropolyanions- organometallics
Redox stability in water – hydrogen over voltage – oxygen over voltage – Latimer, Frost and
Pourbaix diagrams – Electrometallurgy - Ellingham diagram.

Text Books
I. H.J.Arnikar., Essentials of nuclear chemistry, Revised Fourth edition, 1995, New Age
International Publishers, Reprint 2009.
II. P.S.Kalsi and J.P.Kalsi., Bioorganic, Bioinorganic and Supramolecular chemistry,
Fourth edition, New Age International Publishers, 2007.
III. R.Gopalan and V.Ramalingam. Concise coordination chemistry, First edition, 2001,
Vikas Publishing House Private Ltd., Third reprint, 2007.
IV. Wahid U.Malik, G.D.Tuli and R.D.Mada.n, Selected Topics in Inorganic Chemistry, First
edition, S.Chand and Company Ltd., 1976 (Reprint 1998).
V. F.Albert Cotton, Geoffrey Wilkinson, Carlos. A.Murilo and Manfred Bochmann.,
Advanced inorganic chemistry, Sixth edition, Wiley India, 2004 (Reprint 2008).
VI. G.S.Manku., Theoretical principles of Inorganic chemistry, First edition, Tata McGraw-
Hill Publishing Company Ltd., 1980 (Twentieth reprint).

Reference Books
1. Bodie Douglas, Darl McDaniel and John Alexander., Concepts and Models of Inorganic
Chemistry, Third edition, Wiley India Ltd., 2006.
2. Asim.K.Das., Bioinorganic Chemistry, First edition, Books and Allied (P) Ltd., 2007
(Reprint 2009).
3. M.Satake and Y.Mid., Bioinorganic Chemistry, First edition, Discovery Publishing
House, 2001( Reprint 2003).
4. Stephen J. Lippard, Jeremy M. Principles of bioinorganic chemistry Berg.Mill
Valley, Calif. University Science Books, 1994.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Supramolecular Chemistry 4 0 0 4

Aim: To introduce and demonstrate the importance of supramolecular (non-covalent

interactions) complex materials and applications.

Objective: To impart knowledge of types of supramolecules, structures their applications as

organic materials, sensors, and devices.

Outcome: The students will acquire knowledge of,

 Molecular recognition and nature of bindings involved in biological systems
 Structure of supramolecules of various types in solution and solid state
 Applications of supramolecules in miniaturization of molecular devices

Unit-I Supramolecular chemistry: Basic concepts, principles and history (15 hrs)
Introduction to Supramolecular chemistry- Basic concepts, principle and history. Nature of
binding interactions in supramolecular structures: ion-ion, ion-dipole, dipole-dipole, H-bonding,
cation-π, anion-π, π-π and vander waal interactions.

Unit-II Receptors: synthesis, structure and binding (15 hrs)

Synthesis and structures of crown ethers, Lariat ethers, Podands, Cryptands, Spherands,
Calixarene, Cyclodextrins, Cyclophanes, Cryptophanes, Carcerands and hemicarcerands, Host-
guest interactions, Preorganisation and complimentarity, Lock and key analogy. Binding of
cationic, Anionic, Ion pair and neutral guest molecules.

Unit-III Self-assembly molecules (15 hrs)

Design, Synthesis and Properties of the molecules, Self assembly by H-bonding, Catenanes,
Rotaxanes, Dendrimers and Supramolecular gels. Relevance of supramolecular chemistry to
mimic biological system.

Unit-IV Supramolecular Reactivity and Catalysis (15 hrs)

Catalysis by reactive macrocyclic cation receptor molecules. catalysis by reactive anion receptor
molecules. catalysis with cyclophane type receptors. supramolecular metallocatalysis.
cocatalysis: catalysis of synthetic reactions. biomolecular and abiotic catalysis.
Supramolecular chemistry in solution: cyclodextrin, micelles, dendrimmers, gelators.
classification and typical reactions- applications.

Unit-V Supramolecular devices and sensors (15 hrs)

Various types of supramolecular devices, supramolecular light conversion and energy transfer
devices. supramolecular electronic conducting devices - molecular wires, modified and
switchable molecular wires. ion and molecule sensors.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text Books
I. Atwood, J., Steed, J., Supramolecular Chemistry - 2nd ed. Chichester: John Wiley &
Sons, Ltd., 2009.
II. Hans-Joerg Schneider and Anatoly Yatsimirsky, Principles and Methods in
Supramolecular Chemistry, J. Wiley and Sons; 1st Ed. 2000.
III. Kalsi, P.S., and Kalsi, J.P., Bioorganic, Bioinorganic and Supramolecular Chemistry,
New Age International (P) Limited, Publishers, 2010.

Reference Books
1 . Lehn, J. M., Supramolecular Chemistry-Concepts and Perspectives, Wiley –VCH, 1995.
2 . Beer, P.D., Gale, P. A., and Smith, D. K., Supramolecular Chemistry, Oxford University
Press.1999.
3 . Steed, J. W., and Atwood, J. L., Supramolecular Chemistry, Wile, 2000.
4 . Kunitake, T., Ariga, K., Supramolecular Chemistry – Fundamentals and Applications.
Advanced Textbook. Berlin: Springer-Verlag Heidelberg, 2006.

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 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Semester Sub. Code Title of the Paper L P T Credits

IV - Crystal growth 4 0 0 4

Aim: To create interest in the field of crystal growth techniques

Objectives:
 To study the Crystal Growth Theories.
 To understand the Characterization of Crystals.

OutCome:
 NLO organic single crystals have been identified as potential candidates in optical and
electro-optical devices.

Unit-I Nucleation (15 hrs)

Nucleation concept – Kinds of nucleation – Classical theory of nucleation - Spherical nucleus –
Induction period – Measurement - Heterogeneous nucleation – Equilibrium concentration of
embryos – Energy of formation of a critical nucleus - Free energy of formation of a critical
heterogeneous cap shaped and disc shaped nuclei –Nucleation rate.

Unit-II Crystal Growth Theories (15 hrs)

Surface energy theory – Diffusion theory – Adsorption layer theory – Volmer theory –Bravais
theory – Kossel theory – Two dimensional nucleation theory – Free energy of formation of a two
dimensional nucleus – Possible shapes – Rate of nucleation.

Unit-III Crystal Growth Methods (15 hrs)

Growth from Melt, Vapor, Solution (High & Low Temperature Solution Growth). Low
Temperature Solution Growth – Slow Cooling, slow Evaporation & Temperature Gradient
Method.

Unit-IV Characterization of Crystals (15 hrs)

Different techniques for analysis - FTIR, UV as applied to solid crystals - Single Crystal XRD,
SEM, NLO, Micro hardness. Principles of NLO -SHG. Steps in Crystal structure analysis

Unit-V Effects of impurities on crystals (15 hrs)

Doping,Types of Dopants-Imperfections due to doping – Thresholds concentration of doping in
Crystals. Effect of doping on crystals. Methods of detecting imperfections.

47
 Dept. of Chemistry, SCSVMV – BOS-04.01.18 M.Sc (Chemistry)

Text books:
i. Crystal growth for beginners, Ivan.V. Markov, World scientific Private
Ltd.,2016.
ii. Introduction to crystal growth: Principles and practice, H. L. Bhat, CRC Press, 2014.
iii. Solid state chemistry, D.K.Chakrabarthy, New Age International Ltd, 2010.
iv. Solid state chemistry and its applications, Anthony.R. West, John Wiley& sons, 2014.
v. Introduction to Solid state physics, Neil W Ashcroft, N. David Mermin, Cengage Ltd,
2003.

Reference books:
1. Introduction to crystal growth, Klaus-Werner Benz, Wolfgang Neumann, Wiley-VCH,
2014.
2. Crystal Growth , Brain R. Pamplin., Pergamon Press. Oxford, 1980.
3. The growth of crystals from melt, Brice, J.C.. North Holland, Amsterdam, 1973.
1. Crystal Growth in Gels, Heinz K. Henish.. Cambridge University Press, 1973.
2. Cryst allization Mullin, J.W. Academic Press. London.1972.

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