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Agents Causing Coma or Seizures

This document lists various agents that affect pupil size and cause different toxic effects. It categorizes agents based on whether they cause miosis, mydriasis, coma/seizures, changes in heart rate, changes in temperature, changes in blood pressure, and other effects. For each category, it assigns mnemonics to help remember examples of agents that fall into that category.
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0% found this document useful (0 votes)
288 views3 pages

Agents Causing Coma or Seizures

This document lists various agents that affect pupil size and cause different toxic effects. It categorizes agents based on whether they cause miosis, mydriasis, coma/seizures, changes in heart rate, changes in temperature, changes in blood pressure, and other effects. For each category, it assigns mnemonics to help remember examples of agents that fall into that category.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Agents Affecting Pupil Size Muscarinic (DUMBELLS)

Miosis (COPS) Cholinergic Toxidrome (Flashcard)


Cholinergic, clonidine, carbamates Diarrhoea, diaphoresis
Opioids, organophosphates Urination
Phenothiazines (antipsychotics), pilocarpine, Miosis
pontine haemorrhage Bradycardia
Sedative – hypnotics Emesis
Lacrimation
Mydriasis (SAW) Lethargic
Sympathomimetics Salivation
Anticholinergics Nicotinic: Days of the Week
Withdrawal syndromes Mydriasis
Agents Causing Coma or Seizures Tachycardia
Weakness
Agents Causing Coma or Seizures Tremors
Coma (LETHARGIC) Fasiculations
Lead, lithium Seizures
Ethanol, ethylene glycol, ethchlorvyol Somnolent
Tricyclic antidepressants, thallium, toluene
Heroin, hemlock, hepatic encephalopathy, Anticholinergic Toxidrome (Flashcard)
heavy metals, hydrogen sulphide, Blind as a bat;
hypoglycaemics Mad as a hatter;
Arsenic, antidepressants, anticonvulsants, Red as a beet;
antipsychotics, antihistamines Hot as Hades/Hell/Desert;
Rohypnol (sedative hypnotics), risperidone Dry as a bone;
Gamma-hydroxybutyrate (GHB) The bowel and bladder lose their tone, and the
Isoniazid, insulin heart runs alone.
Carbon monoxide, cyanide, clonidine Or…
Can’t See (blurred vision);
Seizures (OTIS CAMPBELL) Can’t pee (urinary retention);
Organophosphates, oral hypoglycaemics Can’t spit (dry mouth);
Tricyclic antidepressants Can’t Shit (constipated)
Isoniazid, insulin Substances that cause bradycardia.
Sympathomimetics, strychnine, salicylates
Camphor, cocaine, carbon monoxide, cyanide, Substances that cause bradycardia
chlorinated hydrocarbons PACED
Amphetamines, anticholinergics Propranolol (Beta blockers), poppies (opiates),
Methylxanthines (theophylline, caffeine), propoxyphene, physostigmine
methanol Anticholinesterase drugs, antiarrythmics
Phencyclidine (PCP), propranolol Clonidine, calcium channel blockers
Benzodiazepine withdrawal, botanicals (water Ethanol or other alcohols
hemlock, nicotine), bupropion, GHB Digoxin, digitalis
Ethanol withdrawal, ethylene glycol Substances that cause tachycardia.
Lithium, lidocaine
Lead, lindane
Cholinergic Toxidrome
Substances that cause tachycardia Substances causing hypertension
FAST CT SCAN
Free Base or other forms of cocaine, Freon Cocaine
Anticholinergics, antihistamines, Thyroid supplements
antipsychotics, amphetamines, alcohol Sympathomimetics
withdrawal Caffeine
Sympathomimetics (cocaine, caffeine, Anticholinergics, amphetamines
amphetamines, phencyclidine [PCP]), solvent Nicotine
abuse, strychnine Substances that cause hyperventilation.
Theophylline, tricyclic antidepressants, thyroid
hormones Substances that cause hyperventilation
Substances that cause hypothermia. PANT
PCP, paraquat pneumonitis, phosgene
Substances that cause hypothermia Acetylsalicylic acid (ASA) and other salicylates
COOLS Noncardiogenic pulmonary oedema, nerve
Carbon monoxide agents
Opioids Toxin-induced metabolic acidosis
Oral hypoglycaemics, insulin Substances that cause hypoventilation
Liquor (alcohols)
Sedative-hypnotics Substances that cause hypoventilation
Substances that cause hyperthermia. SLOW
Sedative-hypnotics (barbiturates,
Substances that cause hyperthermia benzodiazepines)
NASA Liquor (alcohols)
Neuroleptic malignant syndrome, nicotine Opioids
Antihistamines, alcohol withdrawal Weed (marijuana)
Salicylates, sympathomimetics, serotonin Substances causing a wide anion-gap
syndrome acidosis.
Anticholinergics, antidepressants,
antipsychotics Substances causing a wide anion-gap acidosis.
Substances that cause hypotension CAT MUD PILES
Cyanide, carbon monoxide, colchicine
Substances that cause hypotension Alcohol, alcoholic ketoacidosis, acetaminophen
CRASH (in large doses)
Clonidine, calcium channel blockers Toluene
Rodenticides (containing arsenic, cyanide) Methanol, metformin
Antidepressants, aminophylline, Uraemia
antihypertensives Diabetic Ketoacidosis
Sedative-hypnotics Paraldehyde
Heroin or other opioids Isoniazid, iron
Substances causing hypertension. Lactic acidosis
Ethylene glycol
Salicylates
Potentially lethal toxins where early activated
charcoal maybe indicated.
Potentially lethal toxins where early activated
charcoal maybe indicated.
Killer C’s
Cyanide
Colchicine
Calcium channel blockers
Cyclic antidepressants
Cardiac glycosides
Cyclopeptide mushrooms
Cocaine
Cicutoxin (water hemlock)
Salicylates
Substances that do not bind to charcoal.

Substances that do not bind to charcoal


PHAILS
Pesticides
Heavy metals
Acids/alkalis/alcohols
Iron
Lithium
Solvents
Dialysable Toxins.

Dialysable Toxins.
PLASMA TV
Phenobarbitol
Lithium
Acidosis
Salicylates
Metformin
Alcohols
Theophylline
Valproic Acid
Substances amenable to multi-dose activated
charcoal.

Substances amenable to multi-dose activated


charcoal.
ABCDQ
Aminophylline / theophylline
Barbiturates
Carbamazepine / concretion forming drugs
(salicylates)
Dapsone
Quinine

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