Hiv Aids
Hiv Aids
OF
AGRICULTURE & TECHNOLOGY
JKUAT SODeL
Nairobi, Kenya
E-mail: elearning@jkuat.ac.ke
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TDH 1100 Introduction to HIV/AIDs
LESSON 1
General introduction
Learning outcomes
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TDH 1100 Introduction to HIV/AIDs
1.1. Introduction
AIDS has already killed millions of people, millions more con-
tinue to become infected with HIV, and there’s no cure - so
AIDS will be around for a while yet. However, some of us still
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age the cells it replicates in, which is one of the things that can
make an infected creature become ill. Different viruses attack
different parts of the body - some may attack the skin, others
the lungs, and so on.
What makes HIV so dangerous is that it attacks the immune
JJ II system itself - the very thing that would normally get rid of a
J I virus. It particularly attacks a special type of immune system
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TDH 1100 Introduction to HIV/AIDs
cell known as a CD4 lymphocyte and on top of this, HIV has
a number of tricks that help it to evade the body’s defenses,
including very rapid mutation. This means that once HIV has
taken hold, the immune system can never fully get rid of it.
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People can become infected with HIV from other people who
already have it, and when they are infected they can then go on
to infect other people. Basically, this is how HIV is spread.
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TDH 1100 Introduction to HIV/AIDs
one of a number of particularly severe illnesses. It is at this point
that they are said to have AIDS - when they first become seri-
ously ill, or when the number of immune system cells left in the
body drops below a particular point. Different countries have
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this stage the body has very little deference against any sort of
infection.
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TDH 1100 Introduction to HIV/AIDs
condition called AIDS
Human- means the virus can only survive in the hu-
man body because its only human blood that have
CD4+ lymphocytes and these are the cells where HIV
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attaches to.
Immunodeficiency- lack of natural ability of the
body to protect itself against diseases and/or infec-
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TDH 1100 Introduction to HIV/AIDs
to contain about 100million viral copies per ml.
2. AIDS - It is a collection of signs and symptoms caused by
infections and other implications arising from HIV infec-
tion. It may occur 3-10 years after HIV infection.
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TDH 1100 Introduction to HIV/AIDs
4. Infection - Invasion of the body by pathogenic organism.
Not all infections lead to diseases because the body’s de-
fense mechanism resist the effects of toxins (poisonous
substances) and prevents the multiplication and spread of
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pathogens.
5. Infectiousness/ communicability - Capacity of an organism
to spread
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TDH 1100 Introduction to HIV/AIDs
8. Opportunistic infection - These are infections that take
advantage of impairment of the immune system and some-
times are caused by organisms that don’t cause infection or
diseases in man. They take advantage of an immune sys-
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TDH 1100 Introduction to HIV/AIDs
a disease in a community/ region. Endemic diseases can
rapidly become epidemics if environmental factors changes
in a way which favors transmission
11. Epidemic - An acute outbreak of a disease in a commu-
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TDH 1100 Introduction to HIV/AIDs
(National AIDS and STDs Control Program). It involves
anonymous HIV testing of blood samples collected for rou-
tine testing of pregnant women who visit ante natal clinics.
15. Enzymes - Are biological catalysts that enables cellular
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TDH 1100 Introduction to HIV/AIDs
tation i.e. the mutant strain
18. Wild type virus - The original virus that has not undergone
mutation
19. Evidence based approach - An approach to prevent HIV/AIDS
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TDH 1100 Introduction to HIV/AIDs
HIV-2 is less easily transmitted & the period between ini-
tial infection & illness is longer. Its uncommon & concen-
trated in West Africa. E.g. Senegal, Ghana, Mali, Burkina
Faso, Ivory Coast.
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TDH 1100 Introduction to HIV/AIDs
Group O appears to be restricted to West-central Africa
Group N was discovered in 1998 in Cameroon & is ex-
tremely rare.
More than 90% of HIV-1 infections belong to group M
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TDH 1100 Introduction to HIV/AIDs
1.4. Origins, Theories and History of HIV/AIDS
The origin of AIDS and HIV has puzzled scientists ever since
the illness first came to light in the early 1980s. For over twenty
years it has been the subject of debate and the cause of countless
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TDH 1100 Introduction to HIV/AIDs
completely suppressed. Medics wrote their investigations in a
journal.
In 1983, it was discovered that the symptoms that were ear-
lier observed were caused by a certain virus called immunodefi-
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TDH 1100 Introduction to HIV/AIDs
find the source of AIDS, it is necessary to look for the origin
of HIV, and find out how, when and where HIV first began to
cause disease in humans.
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TDH 1100 Introduction to HIV/AIDs
significant differences from HIV-1.
• Hunter theory
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TDH 1100 Introduction to HIV/AIDs
calls for an outright ban on bush meat hunting to prevent simian
viruses being passed to humans.
ple in the Belgian Congo, Ruanda and Urundi in the late 1950s.
To be reproduced, live polio vaccine needs to be cultivated in
living tissue, and Hooper’s belief is that Chat was grown in kid-
ney cells taken from local chimps infected with SIVcpz. This,
he claims, would have resulted in the contamination of the vac-
cine with chimp SIV, and a large number of people subsequently
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becoming infected with HIV-1. However, in February 2000 the
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TDH 1100 Introduction to HIV/AIDs
Wistar Institute in Philadelphia (one of the original places that
developed the Chat vaccine) announced that it had discovered
in its stores a phial of polio vaccine that had been used as part
of the program. The vaccine was subsequently analysed and in
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April 2001 it was announced that no trace had been found of ei-
ther HIV or chimpanzee SIV. A second analysis5 confirmed that
only macaque monkey kidney cells, which cannot be infected
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TDH 1100 Introduction to HIV/AIDs
on inoculation and other medical programs, the huge quantities
of syringes needed would have been very costly. It is therefore
likely that one single syringe would have been used to inject mul-
tiple patients without any sterilization in between. This would
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tered, even if the SIV within the original person infected had
not yet converted to HIV.
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TDH 1100 Introduction to HIV/AIDs
this original infection could have lead to an epidemic. During
the late 19th and early 20th century, much of Africa was ruled
by colonial forces. In areas such as French Equatorial Africa
and the Belgian Congo, colonial rule was particularly harsh and
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TDH 1100 Introduction to HIV/AIDs
camps actively employed prostitutes to keep the workers happy,
creating numerous possibilities for onward transmission.
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TDH 1100 Introduction to HIV/AIDs
gay men through Hepatitis B vaccine trials.
not how or why. The scientists calculated how far back in time
one could need to go for all the HIV-viral subtypes to have a
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TDH 1100 Introduction to HIV/AIDs
engineering technology available to ’create’ the virus at the time
that AIDS first appeared.
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TDH 1100 Introduction to HIV/AIDs
suddenly decide to settle His score with homosexuals and drug
addicts rather than any other ’sinners’. The Bible clearly speaks
of a future (and imminent) judgment time when all sinners - no
matter what their specific practice - will have to pay the penalty
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for their sins. It does not tell, however, of a God who prejudges
particular situations and who picks out special groups for early
condemnation. Clearly, there are God-given laws which govern
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TDH 1100 Introduction to HIV/AIDs
itation from God, many Africans believe that AIDS is caused
by another supernatural power - witchcraft and they use anti-
witchcraft rituals and objects to counteract the infection.
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TDH 1100 Introduction to HIV/AIDs
1.5. Sex and Sexuality
1.5.1. What is sex education?
Sex education, is sometimes called sexuality education or sex
and relationships education. It’s the process of acquiring in-
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TDH 1100 Introduction to HIV/AIDs
1.5.2. Aims of sex education
To reduce the risks of potentially negative outcomes from
sexual behaviour like unwanted or unplanned pregnancies
and infection with STDs.
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TDH 1100 Introduction to HIV/AIDs
semen from the penis & as a result the woman may
become pregnant.
– Sex abuse- Illegal sexual activities esp as practiced
on children by adults
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TDH 1100 Introduction to HIV/AIDs
Genetic makeup of a person i.e tribe
Curiosity –the urge to discover
Availability of sexually explicit material e.g. pornography
Breakdown of mechanism of social control
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Poverty
Idleness
Alcoholism & drug addiction
Attitude towards premarital sex e.g European countries
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TDH 1100 Introduction to HIV/AIDs
Homosexuality
Lesbianism
Incest
Rape - one partner is willing
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Prostitution
Sugar mummies/daddies
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TDH 1100 Introduction to HIV/AIDs
Observation
Literature-novels
Professionals-doctors, teachers
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TDH 1100 Introduction to HIV/AIDs
Sex with virgins cures AIDS/ raping young girls cure AIDS
Women should never say no to sex
Sex with condoms is not real sex
Have sex early to know if you are functioning well
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TDH 1100 Introduction to HIV/AIDs
Global Distribution and Trends of HIV/AIDS - Com-
parative Trends
Trends - Involves looking at the direction HIV/AIDS is
taking, the way it is affecting people, and, what measures
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grossly affected.
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TDH 1100 Introduction to HIV/AIDs
Exercise 1. Revision Questions
Give an account of the limitations of Oral Polio Vaccine The-
ory as a possible explanation to the origin of HIV
Example . Describe the difference Between HIV and AIDS?
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TDH 1100 Introduction to HIV/AIDs
Learning Activities
Read more papers and journal articles on current advances in
HIV/AIDs research. Visit the reproductive health clinic/ section
in a hospital around you and get to learn various methods used
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Assignments
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TDH 1100 Introduction to HIV/AIDs
References and Additional Reading Materials
1. Maranga R. O, Muya S. M and Ogila K. O (2008) Funda-
mentals of HIV/AIDS Education. Signon Publishers.
2. Barry D. S. (1999) AIDS and HIV in Perspectives. CPU.
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ISBN-13: 9780521627665
3. Ellison G. Parker M., Camphpbell C (2003) Learning from
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Solutions to Exercises
Exercise 1. Fertility myth - Common belief that one engage
in sex to enhance fertility in future. This not true. People have
to multiply to fill the earth, a literal translation of a bibli-
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ever fallen sick or become mad for not engaging in sexual inter-
course. Having a venereal disease is considered a badge of honor
that confirms manhood. Venereal diseases confers no honor to
any man Venereal disease is cured if the man has sex with a
virgin. This is not true. On the contrary the Venereal disease
JJ II sufferer will transmit the disease to the virgin. Special food
J I and exercise will make the penis grow big. This is not true.
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TDH 1100 Introduction to HIV/AIDs
Whatever that is good for other body parts is also good for sex
organs. Men have stronger sexual urges than women. Men sex
drive is believed to be boundless and irrepressible. This is not
true. Sexual urge is equal in both the sexes. It is generally said
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not true One can’t get pregnant during the first sex intercourse.
Common believe that there is a grace period between the first
sexual encounter and getting pregnant - like the payment sched-
ule on credit card. This one isn’t true. One can’t get pregnant
during unprotected sex if the man pulls out before he ejaculates.
JJ II This is not true. Some small amounts of sperm containing se-
J I men may be deposited in the vagina before ejaculation. Other
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TDH 1100 Introduction to HIV/AIDs
remain in the urethra after ejaculation and can fertilize an ova.
A woman is not considered to be a female if she cannot con-
ceive a child.The femininity of a person is not judged by the
ability to conceive a child. There are other criteria. Common
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