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Omocysteine: Increased Levels of Homocysteine in The Blood

Homocysteine is an amino acid produced by the body from methionine using B vitamins. Elevated homocysteine levels have been linked to various health issues like heart disease and stroke. Factors that can increase homocysteine include certain drugs, smoking, alcohol, and deficiencies in B6, B12, and folic acid. Testing homocysteine levels provides a more accurate cardiovascular risk assessment than cholesterol. Levels above 15 umol/L are considered high and can be classified as moderate, intermediate, or severe. Dietary and supplement changes focused on B vitamins and other cofactors can help lower an elevated homocysteine level.

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85 views2 pages

Omocysteine: Increased Levels of Homocysteine in The Blood

Homocysteine is an amino acid produced by the body from methionine using B vitamins. Elevated homocysteine levels have been linked to various health issues like heart disease and stroke. Factors that can increase homocysteine include certain drugs, smoking, alcohol, and deficiencies in B6, B12, and folic acid. Testing homocysteine levels provides a more accurate cardiovascular risk assessment than cholesterol. Levels above 15 umol/L are considered high and can be classified as moderate, intermediate, or severe. Dietary and supplement changes focused on B vitamins and other cofactors can help lower an elevated homocysteine level.

Uploaded by

Rukaphuong
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HOMOCYSTEINE

Homocysteine is a sulfur-containing amino acid that the body makes from foods containing methionine using
Vitamins B6, B12 and folic acid.

• Homocysteine can be recycled back into methionine using vitamin B12-related enzymes.

• Homocysteine can be converted to cysteine, with vitamin B6 facilitating this reaction.

• Cysteine (covered in class 5) is an important amino acid which has many roles in the body including the
metabolism of iron, zinc and copper, as well as being an anti-oxidant.

Increased levels of homocysteine in the blood

• When homocysteine cannot be converted into cysteine or back into methionine, blood levels increase.

• Elevated homocysteine levels in the body have been related to heart attack, stroke, hardening of the
arteries, heart disease, blood clots and perhaps the development of Alzheimer's disease.

• Narrow carotid arteries have been correlated with high homocysteine blood levels.

Contributing factors to an elevated homocysteine level:

• Diet • Smoking • High alcohol intake • Rheumatoid arthritis

• Poor lifestyle • High coffee intake • Diabetes • Poor thyroid function

• Some prescription drugs such as proton pump inhibitors (PPI) used to treat acid reflux

• Monosodium glutamate and Nutrasweet can drastically increase homocysteine levels in the bloodstream

Elevated blood levels of homocysteine have been associated with the following health issues:

• Cardiovascular disease • Cancer • Miscarriage • Infant seizures

• Parkinson’s • Poor memory • Pernicious anemia • Neural tube defects in infants

• Alzheimer’s • Dementia • Osteoporosis • Stroke in newborn infants

• Poor concentration • Depression • Abnormal bones in children • Nearsightedness in children

• Mental retardation • Diabetes • Broken bones in the elderly • Pre-eclampsia in pregnancy

• Impaired judgement • Migraines

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Homocysteine Levels in the bloodstream

Measuring homocysteine in the bloodstream is a more accurate measurement of the risk of cardiovascular
disease than cholesterol.

Most laboratories list a normal homocysteine level as between 4 - 15 micromoles/Liter (µmol/L).

• Anything above 15 is considered high.

• An optimal level is below 10 - 12.

• Blood serum homocysteine levels are typically higher in men than in women and the level tends to
increase with age.

Elevated homocysteine has 3 classifications:

1. Moderate (15 to 30 µmol/L) 2. Intermediate (30 to 100 µmol/L) 3. Severe (greater than 100 µmol/L)

To Lower a High Homocysteine Level

• Make dietary changes • Folic acid • B12 • B6 • B3 • Betaine

Muscle Test for Elevated Homocysteine Levels:

1. Test an indicator muscle to make sure the person is strong in the clear.

2. Expose the person to homocysteine by placing a vial (109 from the Biochemical Test Kit) on the person’s
stomach and retest the indicator muscle.

3. If it goes weak, that means the person’s homocysteine levels are too high.

Correction:

1. While keeping the homocysteine on the person’s stomach, add Folic acid, B12, B6, B3, and betaine
individually and test one by one.

2. They need whichever make the person test strong.

3. Also, instead of testing each individually, you can use homocysteine factors, which contains all of the
items in one tablet. NeoLife’s Lipotropic Adjunct has these.

4. Muscle test to find out the daily dosage.

• People with MTHFR (Methylenetetrahydrofolate reductase gene variant) can’t metabolize B12 and
folic acid unless it is methylated.

• People with MTHFR will probably have a high homocysteine level but unmethylated B12 and folic
acid won’t be helpful for them.

• Biotics has a methylated folic acid and B12 supplement called Methylfolate Plus that is ideal for them.

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