?At the laboratory experiment the leukocyte culture was mixed with staphylococci.

neutrophile leukocytes engulfed and digested bacterial cells. This process is

termed:
+ Phagocytosis
- Pinocytosis
-Diffusion
-Facilitated diffusion
- Osmosis

?In the surgical department of a hospital there was an outbreak of hospital

infection that showed itself in often postoperative wound abscesses.
Bacteriological examination of pus revealed aurococcus. What examination shall be
conducted to find out the source of this causative agent among the department
personnel?
+ Phagotyping
- Microscopical examination
- Serological identification
-Biochemical identification
- Estimation of antibiotic susceptibility

?Because of suspected intrahospital infection in the neonatal department of the

maternity home the inspection was carried out. In some children and on some general
things Staphylococcus aureus was revealed. What properties of these cultures allow
to establish their origin from one source?
-Antibioticogramma
- Antigenic structure
- Biochemical activity
+ Phagotype
- Chromogenesis

?In the surgical department of a dental clinic cases of hospital-acquired

staphylococcal infection were registered which was caused by strains with multiple
drug resistance. Such feature can be identified by presence of:
+ R-plasmids
- F-plasmids
- Exotoxins
-Temperate bacteriophages
- Virulent bacteriophages

?Staphylococci grow well in ordinary media but inoculation of blood and egg- yolk
salt agar should be done to separate pure bacterial cultures from diseased tissue.
What is the purpose of those media?
+ To define disease- producing factor
-To define tinctorial properties
-To study antigenic properties
-To define bacterial mobility
-To define antibiotic susceptibility

?During inspectation of dental tools for sterility in one case gram-positive cocci
were detected. They were situated in clusters and yielded positive plasma
coagulation reaction; the cocci were fermenting mannitol in anaerobic conditions
and exhibiting lecithinase activity. What microorganism as detected?
-St. saprophiticus
- St. epidermidis
- Corynebacterium xerosis
+ Staph. aureus
- Str. Pyogenes

?Microbiological purity of tableted drugs had been tested at factory. Samples

cultivation in mannitol salt agar resulted in growth of golden-yellow colonies,
microscopic examination of colonies detected grampositive globular bacteria
positioned in clusters; microorganisms had plasma coagulation properties. What pure
bacterial culture was obtained?
+ Staphylococcus aureus
- Enterobacteriaceae
- Staphylococcus epidermidis
-Staph. saprophyticus
- Pseudomonas aeruginosa

?A 65-year-old man has purulent abscess on his neck. Analyses revealed a culture of
gram-positive cocci with plasmocoagulase activity. This culture relates most likely
to:
+ Staphylococcus aureus
- Streptococcus pyogenes
- Staphylococcus epidermidis
-Staph. saprophyticus
- �

?Examination of a patient with pustular skin lesions allowed to isolate a causative

agent that forms in the blood agar roundish yellow middle-sized colonies surrounded
by haemolysis zone. Smears from the colonies contain irregularshaped clusters of
gram-positive cocci. The culture is oxidase- and catalasepositive, ferments
mannitol and synthesizes plasmocoagulase. What causative agent was isolated?
+ Staphylococcus aureus
- Streptococcus agalactiae
- Streptococcus pyogenes
-Staphylococcus epidermidis
- -

?From the purulent exudate of a patient with odontogenic phlegmon a pure culture of
Gram(+) microorganisms was segregated. This culture was lecithinously active,
coagulated plasma of a rabbit, decomposed mannitol under anaerobe conditions. What
microorganism may have contributed to the origin of suppurative complication?
+ S.aureus
- S.epidermidis
- S.pyogenes
-S.viridans
- S.mutans

?Purulent discharges of a patient with a mandibulofacial phlegmon contain spheroid

microorganisms making S-shaped colonies with golden pigment that produce
lecithinase, plasmocoagulase, hemolysin and decompose mannitol under anaerobic
conditions. Specify the kind of microorganisms that had caused the suppuration:
+ S. aureus
- Str. pyogenes
- Str. mutans
-S. epidermidis
- Str. Sanguis

?A 15-year-old patient consulted a dermatologist about a painful lump in the

armpit. Objectively: there is a walnut-sized node, lymphadenitis, infiltration of
the surrounding tissues. The patient has been diagnosed with hidradenitis. What is
the most likely causative agent of this disease?
+Staphylococci
- Streptococci
- Proteus vulgaris
- Pseudomonas aeruginosa
-Mixed infection
?Microscopy of a smear obtained from a patient with acute purulent periostitis
revealed gram-positive bacteria arranged in clusters resembling bunch of grapes.
What microorganisms is this morphology typical for?
+ Staphylococci
- Sarcina
- Tetracocci
-Candida fungi
- Streptococci

?Pathogenic staphylococcus was obtained from the purulent wound of the patient. Its
antibiotic sensitivity was determined to be as follows: penicillin growth
inhibition zone - 8 mm; oxacillin - 9 mm, ampicillin - 10 mm, gentamicin - 22 mm,
lincomycin - 11 mm. What antibiotic should be chosen for treatment in this case?
+ Gentamicin
- Penicillin
- Ampicillin
-Oxacillin
- Lincomycin

?Analysis of sputum taken from a patient with suspected pneumonia revealed rather
elongated gram-positive diplococci with somewhat pointed opposite ends. What
microorganisms were revealed in the sputum?
+ Streptococcus pneumoniae
- Staphylococcus aureus
- Klebsiella pneumoniae
-Neisseria meningitidis
- Neisseria Gonorrhoeae

?Analysis of sputum taken from a patient with suspected pneumonia revealed slightly
elongated gram-positive diplococci with tapered opposite ends. What microorganisms
were revealed in the sputum?
+ Stretpococcus pneumoniae
-Neasseria gonorrhoeae
- Neisseria meningitidis
- Staphylococcus aureus
-Klebsiella pneumonia

?A patient has a suspected pneumonia. In his sputum there were revealed

grampositive diplococci, prolonged with the slightly pointed opposite ands. What
microorganisms are revealed in the sputum?
-Staphylococcus aureus
- Neisseria gonorrhoeae
- Neisseria meningitidis
-Klebsiella pneumoniae
+ Streptococcus pneumonia

?A 22 y.o. man complains of acute throat pain, increasing upon swallowing during 3
days. Body temperature 38,30 C, neck lymph nodules are slightly enlarged and
painful. Pharyngoscopically � tonsilar hyperemia, enlargement and edema, tonsils
are covered by round yellow fibrinous patches around crypts openings. Beta-
haemolytic streptococcus in swab analysis. What is the diagnosis?
+ Acute membranous tonsilitis
- Acute follicular tonsilitis
- Pharyngeal diphtheria
-Infectious mononucleosis
- Pharyngeal candidosis

?A 10-year-old girl was admitted to a hospital with carditis presentations. It is

known from the anamnesis that two weeks ago she had exacerbation of chronic
tonsillitis. What is the most likely etiological factor in this case?
+ Streptococcus
- Staphylococci
- Pneumococci
- Klebsiella
-Proteus

?A 40-year-old woman was diagnosed with glomerulonephritis based on her clinical

symptoms and the results of urine analysis. Anamnesis states chronic tonsillitis.
What microorganisms are the most likely cause for the kidney damage in this case?
+ Streptococci
- Staphylococci
- Escherichia
-Mycoplasma
- Meningococci

?A 10-year-old child has painful swallowing, neck edema, temperature rise up to 39

oC, the whole body is covered with bright-red petechial rash. Back of the throat
and tonsils are hyperemic, the tongue is crimsoncolored. Tonsillar surface is
covered with isolated grayish- colored necrosis nidi. What disease is it?
+ Scarlet fever
- Meningococcal nasopharyngitis
- Diphtheria
- Influenza
- Measles

?A child is 10 years old. The following presentations have developed: sharp pain
during swallowing, swollen neck, body temperature rise up to 39,0oC, bright-red
finely papular rash all over the body. Pharynx and tonsils are sharply hyperemic
("flaming pharynx"), "crimson tongue". On the tonsils surface there are isolated
greyish necrosis focuses. What disease it might be?
+ Scarlet fever
- Meningococcal nasopharynxgitis
- Diphtheria
- Influenza
- Measles

?A boy is 7 y.o. Objectively: against the background of hyperemic skin there is

knobby bright-pink rash on his forehead, neck, at the bottom of abdomen, in the
popliteal spaces; nasolabial triangle is pale. Examination of oropharyngeal surface
revealed localized bright-red hyperemia; tonsils are swollen, soft, lacunas contain
pus, tongue is crimson. Cervical lymph nodes are enlarged, dense and painful. What
is the most probable diagnosis?
+ Scarlet fever
- Rubella
- Whooping cough
-Diphtheria
- Infectious mononucleosis

?A 9-year-old boy has acute onset of disease: sore throat, body temperature rise up
to 39,5oC; on the second day diffuse skin rash was detected all over his skin
except for nasolabial triangle. On examination of oral cavity: crimson tongue,
"flaming pharynx", necrotic tonsillitis. What diagnosis is the most likely?
+ Scarlet fever
- Measles
- Diphtheria
-Influenza
- Meningococcemia

?A 7 y.o. girl fell ill abruptly: fever, headache, severe sore throat, vomiting.
Minute bright red rash appear in her reddened skin in 3 hours. It is more intensive
in axillae and groin. Mucous membrane of oropharynx is hyperemic. Greyish patches
is on the tonsills. Submaxillary lymph nodes are enlarged and painful. What is your
diagnosis?
+ Scarlet fever
- Measles
- Rubella
-Pseudotuberculosis
- Enteroviral infection

?In a 2-year-old child with catarrhal presentations and skin rash a pediatrician
suspected scarlet fever. The child was given intracutaneously a small dose of serum
antibody to the streptococcal erythrogenic toxin; on the site of injection the rash
disappeared. What do the reaction results mean?
+ The clinical diagnosis was confirmed
- The child has hypersensitivity to the erythrogenic toxin
- The disease wasn�t caused by haemolytic streptococcus
-The whole serum dose may be injected intravenously
- The child has very weak immune system

?A 2 y.o. child has catarrhal effects and skin eruption. A doctor suspected scarlet
fever. The child was injected intracutaneously with some serum to the erythrogenic
streptococcus toxin, on the spot of injection the eruption disappeared. What do the
reaction results mean?
+ They confirm the clinical diagnosis
- The child has hypersensitivity to the erythrogenic toxin
- The disease was caused by non-hemolytic streptococcus
-The complete dose of serum could be introduced intravenously
- The child�s immune system is very weakened

?A 7 year old child often suffers from streptococcus angina. Doctor suspected
development of rheumatism and administered serological examination. The provisional
diagnosis will be most probably confirmed by presence of antibodies to the
following streptococcus antigen:
+ O-streptolysin
- C-carbohydrate
- M-protein
-Erythrogenic toxin
- Capsular Polysaccharide

?A male patient has been diagnosed with acute post-streptococcal

glomerulonephritis. It is most likely that the lesion of the basement membrane of
renal corpuscles was caused by the following allergic reaction:
+ Immune complex
- Anaphylactic
-Cytotoxic
-Delayed
-Stimulated

?A patient has been diagnosed with acute glomerulonephritis that developed after he
had had streptococcal infection. It is most likely that the affection of basal
glomerular membrane is caused by an allergic reaction of the following type:
+ Immune complex
- Anaphylactic
-Cytotoxic
-Delayed
-Stimulated

?
10 days after having quinsy caused by beta-hemolytic streptococcus a 6-year- old
child exhibited symptoms of glomerulonephritis. What mechanism of glomerular lesion
is most likely in this case?
+ Immunocomplex
- Anaphylaxis
- Cellular cytotoxicity
-Atopy
- Antibody-dependent cell-mediated cytolysis

?Blood of a patient with presumable sepsis was inoculated into sugar broth. There
appeared bottom sediment. Repeated inoculation into blood agar caused growth of
small transparent round colonies surrounded by hemolysis zone. Examination of a
smear from the sediment revealed gram-positive cocci in form of long chains. What
microorganisms are present in blood of this patient?
+ Streptococci
- Micrococci
-Staphylococci
-Tetracocci
-Sarcina

?Microscopy of a dental plaque revealed a large number of cocci arranged in pairs

and strings, as well as Gram-positive bacilli which were likely to be the cause of
cariogenesis. What microorganism associations are involved in the development of
dental caries?
+ S.mutans, streptococci and lactobacilli
- S.salyvarius, streptococci and lactobacilli
- S.mutans, streptococci and corynebacteria
-S.aureus and lactobacilli
- S.salyvarius, streptococci and enterococci

?A patient with streptococcal gingival infection was prescribed a medication that

contains beta lactam ring in its structure. What preparation belongs to this group?
+ Benzylpenicillin
- Rifampicin
- Erythromycin
-Streptomicin sulfate
- Chloramphenicol

?A patient with streptococcal infection of gums was prescribed a drug that

contained beta-lactam ring in its structure. Which drug relates to this group?
+ Benzylpenicillin
- Rifampicin
- Erythromycin
-Streptomycin sulfate
- Chloramphenicol

?During examination of a patient a dentist revealed a lot of "white spots zones of

enamel demineralization. What microorganisms take part in the development of this
process?
+ Streptococcus mutans
- Streptococcus salivarius
- Streptococcus pyogenes
-Veilonella parvula
- Staphylococcus epidermidis

?Bacteriological examination of purulent discharges from the urethra revealed gram-

negative bacteria looking like coffee beans. They were localized in the leukocytes
and could decompose glucose and maltose to acid. These are the causative agents of
the following disease:
+ Gonorrhoea
- Syphilis
- Melioidosis
-Soft chancre
- Veneral lymphogranulomatosis

?Gramnegative bin-shaped diplococcus inside and outside of leucocytes were detected

on bacteriological examination of the purulent exudates from the cervix of the
uterus. Name the causative agent of purulent inflammation of the cervix of the
uterus.
-Haemophilus vaginalis
- Chlamidia trachomatis
- Calymmatobacterium granulomatis
+ Neisseria gonorrhoeae
- Trichomonas vaginalis

?Bacteriological analysis of purulent discharges from urethra revealed presence of

gram-negative bacteria resembling of coffee beans, which were able to decompose
glucose and maltose into acid. They were found in the leukocytes. These bacteria
are causative agents of the following disease:
+ Gonorrhoea
- Venereal lymphogranulomatosis
- Melioidosis
-Ulcul molle
- Syphilis

?Bacteriological examination of purulent discharges from urethra revealed some

bacteria that had negative Gram�s stain, resembled of coffee corns, decomposed
glucose and maltose up to acid. They were located in leukocutes. What disease do
they cause?
+ Gonorrhea
- Syphilis
- Pseudocholera
-Soft chancre
- Venereal lymphogranulomatosis

?Microscopy of a female patient�s swabs made from vaginal secretion revealed

gramnegative bean-shaped diplococci. What provisional diagnosis can be made?
+ Gonorrhoea
- Syphilis
- Clamidiosis
-Mycoplasma
- Toxoplasma

?Microscopic study of discharges from urethra of a patient suffering from acute

urethritis revealed bean-shaped microorganisms up to 1 micrometer in diameter
arranged in pairs and placed inside the leukocytes. What microorganisms are these?
+ Gonococci
- Meningococci
- Tetracocci
- Streptococci
- Staphylococci

?A newborn child has hyperemia, edema of mouth mucous membrane, small erosions with
viscous muco-purulent discharge. Examination of muco-pus smears reveals a great
number of leukocytes containing gram-negative diplococci. The same microorganisms
can be found outside the leukocytes. What is the most probable diagnosis?
+ Gonococcal stomatitis
- Toxoplasmosis
- Prenatal syphilis
-Staphylococcal stomatitis
- Blennorrhea

?An 18 year old woman consulted a gynecologist about the pain in the lower part of
abdomen, fever up to 37,5oC, considerable mucopurulent discharges from the genital
tracts, painful urination. Vaginal and speculum examination results: the urethra is
infiltrated, cervix of the uterus is hyperemic, erosive. The uterus is painful,
ovaries are painful, thickened; fornixes are free. Bacterioscopy test revealed
diplococcus. What diagnosis is the most probable?
+ Recent acute ascending gonorrhea
- Trichomoniasis
- Candydomycosis
-Chronic gonorrhea
- Chlamydiosis

?On the fifth day after a casual sexual contact a 25-year-old female patient
consulted a doctor about purulent discharges from the genital tracts and itch.
Vaginal examination showed that vaginal part of uterine cervix was hyperemic and
edematic. There was an erosive area around the external orifice of uterus. There
were mucopurulent profuse discharges from the cervical canal, uterine body and
appendages exhibited no changes. Bacterioscopic examination revealed bean-shaped
diplococci that became red after Gram�s staining. What is the most likely
diagnosis?
+ Acute gonorrheal endocervicitis
- Trichomonal colpitis
-Candidal vulvovaginitis
-Bacterial vaginism
- Clamydial endocervicitis

?A 28-year-old patient has been admitted to the gynecological department three days
after a casual coitus. She complains about pain in her lower abdomen and during
urination, profuse purulent discharges from the vagina, body temperature rise up to
37,8oC The patient was diagnosed with acute bilateral adnexitis. Supplemental
examination revealed: the 4th degree of purity of the vaginal secretion, leukocytes
within the whole visual field, diplococcal bacteria located both intra- and
extracellularly. What is the etiology of acute adnexitis in this patient?
+ Gonorrheal
- Colibacterial
- Chlamydial
-Trichomonadal
- Staphylococcal

?A patient consulted a venereologist about painful urination, reddening of the

external opening of urethra, profuse purulent discharges from the urethra. He
considers himself to be ill for 3 days. He also associates the disease with a
casual sexual contact that took place for about a week ago. If provisional
diagnosis "acute gonorrheal urethritis" will be confirmed, then bacteriological
study of urethral discharges will reveal:
+ Gram-negative diplococci
- Gram-positive diplococci
- Spirochaete
-Proteus vulgaris
- Mycoplasma

?A female woman has been clinically diagnosed with gonorrhea. Which of the
following studies can be used to confirm the diagnosis?
+ Microscopy of the pathological material
- Disinfection of laboratory animals
- Bacteriophage test
- Hemagglutination reaction
- Immobilization test

?Clinical diagnosis of a female patient was gonorrhoea. What examination method can
be applied for confirmation of this diagnosis?
+ Microscopy of pathological material
- Infection of laboratory animals
- Test with bacteriophage
-Hemagglutination reaction
- Immobilization reaction

?A 30-year-old female patient has been delivered to the gynaecological department

with complaints of acute pain in the lower abdomen and body temperature 38,8C In
history: sexual life out of wedlock and two artificial abortions. Gynaecological
examination reveals no changes of uterine. The appendages are enlarged and painful
on both sides. Vaginal discharges are purulent and profuse. What study is required
to confirm a diagnosis?
+ Bacteriological and bacterioscopic analysis
- Hysteroscopy
- Curettage of uterine cavity
-Colposcopy
- Laparoscopy

?On admission a 35-year-old female reports acute abdominal pain, fever up to 38,8C,
mucopurulent discharges. The patient is nulliparous, has a history of artificial
abortions. The patient is unmarried, has sexual contacts. Gynecological examination
reveals no uterus changes. Appendages are enlarged, bilaterally painful. There is
profuse purulent vaginal discharge. What study is required to confirm the
diagnosis?
+ Bacteriologic and bacteriascopic studies
-Hysteroscopy
-Curettage of uterine cavity
- Vaginoscopy
- Laparoscopy

?An ophthalmologist suspects blennorrhea (gonococcal conjunctivitis) in a child

with signs of suppurative keratocojunctivitis. What laboratory diagnostics should
be conducted to confirm the diagnosis?
+ Microscopy and bacteriological analysis.
- Serum diagnostics and allergy test.
- Biological analysis and phagodiagnostics.
-Biological analysis and allergy test.
- Microscopy and serum diagnostics.

?A patient who came to the doctor because of his infertility was administered to
make tests for toxoplasmosis and chronic gonorrhoea. Which reaction should be
performed to reveal latent toxoplasmosis and chronic gonorrhoea in this patient?
-RIHA - Reverse indirect hemagglutination assay
- RDHA - Reverse direct hemagglutination assay
- IFA - Immunofluorescence assay
-Immunoblot analysis
+ (R)CFT- Reiter's complement fixation test

?A doctor made the diagnosis of gonorrhoea. It was known from the anamnesis that a
patient had had gonorrhoea before and he had been treated completely. What type of
infection can this new disease be attributed to?
- Superinfection
+ Reinfection
- Secondary infection
- Relapse
-Autoinfection

?Gonorrhoea was revealed in the patient on bacterioscopy of the smear from urethra.
Taking into account that medecines for gonorrhoea are fluorquinolones, patient
should be prescribed:
+ Ciprofloxacin
- Fluorouracil
- Cefazoline
-Urosulfan
- Furazolidone

?A patient has been diagnosed with gonorrhea. As fluoroquinolones are the drugs of
choice for treatment of gonorrhea the patient should be prescribed:
+ Ciprofloxacin
- Furazolidone
- Fluorouracil
-Sulfacarbamide (Urosulfanum)
- Cefazolin

?While studying blood and mucus samples from the nasopharynx, a bacteriologist took
certain measures to conserve the pathogens in the material. Bacterioscopic study
revealed the presence of gram-negative cocci looking like coffee beans and arranged
in pairs or tetrads. Name the pathogen that was isolated by the bacteriologist:
+ Neisseria meningitidis
- Staphilococcus aureus
- Neisseria gonorrhoeae
-Moraxella lacunata
- Acinetobacter calcoaceticus

?Bacterioscopy of nasopharyngeal mucus taken from a 2,5 year old child with
nasopharyngitis revealed gram-negative diplococci looking like coffee grains. ?What
organs of the child are most likely to be affected if these microorganisms
penetrate the blood?
+ Brain tunics
- Cardiac valves
- Renal glomeruli
-Urogenital tracts
- Lymph nodes

?A young woman suddenly developed fever up to 39oC accompanied by a strong

headache. Examination revealed marked nuchal rigidity. Spinal puncture was
performed. Gram-stained smear of cerebrospinal fluid contained many neutrophils and
Gram-negative diplococci. What bacteria could be the cause of this disease?
+ Neisseria meningitidis
- Streptococcus pneumoniae
- Haemophilus influenza
-Staphylococcus aureus
- Pseudomonas aeruginosa

?A 5 y.o. child had a temperature rise up to 400C, acute headache, vomiting,

anxiety, chill. 4 days later there appeared hemorrhagic skin eruption, oliguria and
adrenal insufficiency that caused death. Bacteriological examination of smears from
the child�s pharynx revealed meningococcus. What disease form was revealed?
+ Meningococcemia
- Meningococcal meningitis
- Meningoencephalitis
-Meningicoccal nasopharyngitis
- �

?A 5 year old child has the following symptoms: body temperature up to 40oC, acute
headache, vomiting, anxiety, shiver. 4 days later there appeared hemorrhagic skin
rash, oliguria and adrenal insufficiency that caused death. Bacteriological
examination of pharyngeal smears revealed meningococcus. What form of meningococcal
infection was it?
+ Meningococcemia
- Meningococcal meningitis
-Meningoencephalitis
-Meningococcal nasopharyngitis
- �

?In winter a 3-year-old child has sharp rise of body temperature up to 40-
Hemorrhagic rash is observed on the skin and mucosa. Bean-shaped gram- negative
microorganisms situated in pairs are detected in the blood. What provisional
diagnosis can be made?
+ Meningococcosis
- Gonorrhea
- Scarlet fever
-Influenza
-Diphtheria

?A 4 month old child fell seriously ill: body temperature rose up to 38,5oC, the
child became inert and had a single vomiting. 10 hours later there appeared rash
over the buttocks and lower limbs in form of petechiae, spots and papules. Some
haemorrhagic elements have necrosis in the center. What is the most probable
disease?
+ Meningococcemia
- Rubella
- Influenza
-Haemorrhagic vasculitis
- Scarlet Fever

?The disease of a 21 y.o. patient began with raise of temperature up to 39,0 0C,
headache, chill, repeated vomiting. Rigidity of occipital muscles is determined.
The analysis of liquor revealed: cytosis - 1237 in 1 ml, including: 84%
of neutrophils, 16 % of lymphocytes. On bacterioscopy: gram-negative cocci are
found in liquor. What is the most probable disease?
+ Meningococcal infection: purulent meningitis
- Meningococcal infection: serous meningitis
- Secondary purulent meningitis
-Serous meningitis
- Infectious mononucleosis

?A 1,5 y.o. child fell seriously ill: chill, body temperature rise up to 40,10 C,
then rapid dropping to 36, 20 C, skin is covered with voluminous hemorrhagic rash
and purple cyanotic spots. Extremities are cold, face features are sharpened.
Diagnosis: meningococcosis, fulminant form, infection-toxic shock. What antibiotic
must be used at the pre-admission stage?
+ Soluble Levomycetine succinate
- Penicillin
- Lincomycin
-Gentamycin
- Sulfamonometoxin
?A child with suspected colienteritis was delivered to the infectious disease
hospital. Colibacillus was obtained from the child�s feces. How to determine
whether this bacillus is of pathogenic variety?
-By means of bacteriophage typing
+Agglutination reaction with serum O
- Microscopy of stained smears
-Based on the nature of its growth in Endo medium
- Based on its biochemical properties

?Red colonies spread in the large quantity in the Endo culture medium were revealed
on bacteriological stool examination of a 4-month-old baby with the symptoms of
acute bowel infection. What microorganism can it be?
+ Escherichia
- Salmonella
- Staphylococcus
-Streptococcus
- Shigella

?On bacteriological examination of the defecation of a 4-months-old baby with the

symptoms of acute bowel infection there were revealed red colonies spread in the
large quantity in the Endo environment. What microorganism can it be?
-Staphylococcus
- Streptococcus
- Shigella
-Salmonella
+ Escherichia

?From the defecation of a 6-year-old ill child, who has artificial feeding, the
intestinal bacillus with antigen structure 0-111 is excreted. What is the
diagnosis?
-Food poisoning
- Dysentery-like disease
- Gastroenteritis
+ Coli-enteritis
- Cholera-like disease

?Stool culture test of a 6-month-old bottlefed baby revealed a strain of intestinal

rod-shaped bacteria of antigen structure 0-111.What diagnosis can be made?
+ Colienteritis
- Gastroenteritis
- Choleriform disease
-Food poisoning
- Dysentery-like disease

?12 year old child has the ulcer disease of stomach. What is the etiology of this
disease?
+ Intestinal bacillus
- Helicobacter pylori
- Salmonella
-Lambliosis
- Influenza

?Among junior children of an orphanage an outbreak of intestinal infection with

signs of coli-enteritis was registered. In order to identify isolated causative
agent it is necessary to:
+ To study biochemical properties of the causative agent
- To determine sensitivity to antibiotics
- To study sensitivity to bacteriophages
-Study antigenic properties of the causative agent
- To study virulence of the causative agent

?A 12-year-old boy has been hospitalized for suspected food poisoning. The fecal
samples were inoculated on the Endo agar, which resulted in growth of a large
number of colorless colonies. What microorganism is most likely to be EXCLUDED from
the list of possible causative agents of the disease?
+ Escherichia coli
- Salmonella enteritidis
- Proteus vulgaris
-Pseudomonas aeruginosa
- Yersinia enterocolitica

?Bacteriological examination of a patient with food poisoning required inoculation

of a pure culture of bacteria with the following properties: gramnegative movable
bacillus that grows in the Endo�s medium in form of colourless colonies. A
representative of which species caused this disease?
+ Salmonella
- Shigella
- Yersinia
-Esherichia
- Citrobacter

?On bacteriological study of rinsing water of the patient with food poisoning, the
pure bacterial culture was inoculated with the following properties: gram- negative
motile bacillus in the Endo environment grows like achromic colony. Representative
of what genus has caused the illness?
-Yersinia
- Citrobacter
+ Salmonella
-Shigella
- Escherichia

?It was reported an outbreak of food poisoning connected with consumption of pastry
that had been stored at a room temperature and had duck eggs as one of the
ingredients. What microorganisms might have caused this disease?
+ Salmonella
- Colon bacilli
- Staphylococci
-Legionella
- Comma bacilli

?A 10 month old boy has been ill for 5 days after consumption of unboiled milk.
Body temperature is 38 ? 39oC, there is vomiting, liquid stool. The child is pale
and inert. His tongue is covered with white deposition. Heart sounds are muffled.
Abdomen is swollen, there is borborygmus in the region of ubbilicus, liver is
enlarged by 3 cm. Stool is liquid, dark-green, with admixtures of mucus, 5 times a
day. What is the most probable diagnosis?
+ Salmonellosis
- Staphylococcal enteric infection
- Escherichiosis
-Acute shigellosis
- Rotaviral infection

?A nurse of the kindergarten was taken to the hospital with complaints of acute
pain in parumbilical region, convulsions of lower limbs, multiple bile vomiting,
frequent watery foul feces of green color in huge amounts. At the same time all the
staff in the kindergarden got ill. Two days ago all of them ate cottage cheese with
sour cream. General condition of patients is of moderate severity. Temperature
38,2o- Heart tones: rhythmic and muted. Heart rate 95/min, arterial pressure: 160
mm/Hg. Abdomen is slightly swollen, painful. Liver +2 cm. What is the most likely
diagnosis?
+ Salmonellosis
- Dysentery
- Cholera
-Food toxic infection
- Enterovirus infection

?A 33-year-old male patient developed a condition that had a stormy clinical

course: chills, fever up to 39oC, vomiting, epigastric pain, diarrhea with watery
smelly feces. 6 hours before, he ate a raw egg, fried potatoes with stewed meat,
drank some juice. What pathogen is likely to have caused this condition?
+ Salmonella
- Colibacillus
- Campylobacter
-Shigella
- Vibrio cholera

?A 28 year old patient was admitted to the clinic with complaints of the
temperature rise up to 39,0oC, headache, weakness, constipation on the 9th day of
the disease. On examination: single roseolas on the skin of the abdomen are
present. The pulse rate is 78 bpm. The liver is enlarged by cm. What is the most
probable diagnosis?
+ Typhoid fever
- Leptospirosis
- Brucellosis
-Sepsis
- Malaria

?A 28 y.o. male patient was admitted to the hospital because of high temperature
390C, headache, generalized fatigue, constipation, sleep disorder for 0 days. There
are sporadic roseolas on the abdomen, pulse- 78 bpm, liver is enlarged for 2 cm.
What is the most probable diagnosis?
+ Abdominal typhoid
- Typhus
- Sepsis
-Brucellosis
- Leptospirosis

?A patient with complaints of 3-daylong fever, general weakness, loss of appetite

came to visit the infectionist. The doctor suspected enteric fever. Which method of
laboratory diagnosis is the best to confirm the diagnosis?
+ Detachment of blood culture
- Detachment of myeloculture
- Detachment of feces culture
-Detachment of urine culture
- Detachment of pure culture

?A patient was hospitalized into the infectious diseases unit on the 11th day since
the disease onset and provisionally diagnosed with typhoid fever. What biological
material should be collected from the patient for the analyzes at this stage?
-Roseola secretion
- Blood serum
- Bile
+ Feces
- Urine

?A 50 year old locksmith was diagnosed with typhoid fever. The patient lives in a
separate apartment with all facilities. Apart of him there are also 2 adults in his
family. What actions should be taken about persons communicating with the patient?
+ Bacteriological study
- Antibiotic prophylaxis
- Dispensary observation
-Isolation
-Vaccination

?During the repeated Widal�s agglutination test it was noticed that the ratio of
antibody titers and O-antigens S.typhi in the patient�s serum had increased from
1:100 to 1:400. How would you interpret these results?
+ The patient has typhoid fever
- The patient is an acute carrier of typhoid microbes
- The patient is a chronic carrier of typhoid microbes
-The patient previously had typhoid fever
- The patient was previously vaccinated against typhoid fever

?A patient was brought into the infectional diseases hospital on the 8th day since
the disease onset. The patient complains of headache, malaise, and weakness. A
sample of blood was taken for the serological test. Widal agglutination test
results with blood sample diluted 1:200 and typhoid fever O- diagnosticum were
positive. What diagnosis can be made based on the results of this test?
+ Typhoid fever
- Leptospirosis
- Tuberculosis
-Dysentery
- Cholera

?To conduct serum diagnostics of typhoid fever a test is carried out, when
diagnosticums of three types of microorganisms are being added into different
solutions of patient�s serum; then agglutinate formation is checked. Name the
author of that test.
+ Widal
- Wassermann
- Ouchterlony
-Wright
- Sachs-Witebsky

?A 50-year-old patient with typhoid fever was treated with Levomycetin, the next
day his condition became worse, temperature rised to 39,60�. What caused
worthening?
-Reinfection
- Irresponsiveness of an agent to the levomycetin
- Allergic reaction
+ The effect of endotoxin agent
- Secondary infection addition

?Autopsy of a 46-year-old man revealed multiple brown-and-green layers and

hemmorhages on the mucous membrane of rectum and sigmoid colon; slime and some
blood in colon lumen; histologically - fibrinous colitis. In course of
bacteriological analysis of colon contents S.sonne were found. What is the most
probable diagnosis?
+ Dysentery
- Cholera
- Salmonellosis
-Yersiniosis
- Crohn�s disease

?A patient has been suffering from diarrhea for 5 day. On the fifth day colonoscopy
revealed that membrane of rectum was inflamed, there were greyish-green films
closely adhering to the subjacent tissue. What is the most probable diagnosis?
+ Dysentery
-Nonspecific ulcerous colitis
- Typhoid fever
-Salmonellosis
- Crohn�s disease

?A 71-year-old man had been presenting with diarrhea for 10 days. The feces had
admixtures of blood and mucus. He was delivered to a hospital in grave condition
and died 2 days later.
Bacteriological analysis revealed Shigella. What was the main disease?
+ Dysentery
-Typhoid fever
- Salmonellosis
-Nonspecific ulcerous colitis
- Yersiniosis

?A 28 y.o. man fell seriously ill, he feels chill, has got a fever, body
temperature raised up to 38,50C, paroxysmal pain in the left iliac region, frequent
defecation in form of fluid bloody and mucous mass. Abdomen palpation reveals
painfulness in its left half, sigmoid colon is spasmed. What is the most probable
diagnosis?
+ Acute dysentery
- Amebiasis
- Colibacillosis
-Nonspecific ulcerative colitis
- Malignant tumors of large intestine

?A 30-year-old patient complains of paroxysmal abdominal pain, frequent liquid

stools up to 10 times a day. Throughout the first 3 days he had a fever, since the
2nd day of disease there were scant liquid stools mixed with mucus. On palpation:
tenderness of all colon segments. Sigmoid colon was found spastic. What is your
provisional diagnosis?
+ Acute dysentery
- Intestinal amebiasis
- Salmonellosis
-Cholera
- Balantidiasis

?A 6-year-old child complains of frequent liquid stool and vomiting. On the 2nd day
of disease the child presented with inertness, temperature rise up to 38,2oC, Ps-
150 bpm, scaphoid abdomen, palpatory painful sigmoid colon, defecation 10 times a
day with liquid, scarce stool with mucus and streaks of green. What is a
provisional diagnosis?
+ Shigellosis
- Salmonellosis
- Escherichiosis
-Intestinal amebiasis
- Yersiniosis

?An 8-year-old boy fell ill acutely: he presents with fever, weakness, headache,
abdominal pain, recurrent vomiting, then diarrhea and tenesmus. Stools occur 12
times daily, are scanty, contain a lot of mucus, pus, streaks of blood. His sigmoid
gut is tender and hardened. What is your diagnosis?
+ Dysentery
- Salmonellosis
- Cholera
-Staphylococcal gastroenteritis
- Escherichiosis
?A patient with suspected dysentery has been admitted to the infectious diseases
hospital. Which basic method of laboratory diagnosis must be applied in the first
place?
+ Bacteriological
- Serological
- Allergic
-Biological
- Microscopic

?A patient was taken to the hospital with complaints of headache, high temperature,
frequent stool, stomach pain with tenesmus. Doctor made a clinical diagnosis
dysentery and sent the material (excrements) to the bacteriological laboratory for
analysis. What diagnostic method should the laboratory doctor use to confirm or to
disprove the clinical diagnosis?
+ Bacteriological
- Biological
- Bacterioscopic
-Serological
- Allergic

?The infectious diseases department of a hospital admitted a patient with nausea,

liquid stool with mucus and blood streaks, fever, weakness. Dysentery was
suspected. What method of laboratory diagnostics should be applied to confirm the
diagnosis?
+ Bacteriological
- Serological
- Mycological
-Microscopic
- Protozoological

?A patient diagnosed with acute dysentery has been treated for 3 days in an
infectious diseases hospital. On admission there were complaints of high
temperature, stomachache and fluid excrements with mucus as often as 8-10 times a
day. What sample should be taken for analysis?
+ Feces
- Urine
- Bile
-Liquor
- Blood

?A patient recovered from Sonne dysentery and was once more infected with the same
causative agent. What is such infection form called?
+ Reinfection
- Recidivation
- Superinfection
-Persisting infection
- Chronic infection

?From the fecal sample of a patient Shigella sonne were isolated. What additional
studies are required to identify the source of infection?
+ Phage-typing of the isolated pure culture
- Antibiogram
- Precipitation reaction
-Complement-fixation reaction
- Neutralization reaction

?For the purpose of retrospective diagnostics of recent bacterial dysentery it was

decided to perform serological examination of blood serum in order to determine
antibody titer towards Shiga bacilli. What of the following reactions should be
applied?
+ Passive hemagglutination
- Bordet-Gengou test
- Precipitation
-Hemolysis
- Bacteriolysis

?Retrospective diagnostics of bacterial dysentery involved serological analysis of

blood serum intended for determination of Shigella antibody titer. Which of the
following reactions should be applied for this purpose?
+ Passive haemagglutination
- Complement binding
- Precipitation
-Haemolysis
- Bacteriolysis

?Retrospective diagnostics of old bacillary dysentery required serologic

examination of blood serum in order to determine blood titer to the shigella. What
reaction should be applied for this purpose?
+ Reaction of passive hemagglutination
- Bordet-Gengou test
- Precipitation reaction
-Hemolysis reaction
- Bacteriolysis reaction

?Antigens of Sonne shigella placed on the objects of outdoor environment and

foodstuffs can be revealed by means of a certain test with application of a
diagnostic test system that includes a polystyrene tray with adsorbed specific
antibodies. What reaction is it?
+ Immune-enzyme assay
- Immunofluorescence test
- Passive inverse hemagglutination test
-Direct hemagglutination test
- Immunoelectrophoresis

?A patient has been diagnosed with bacillary dysentery. What drug of those listed
below should be prescribed?
+ Amoxicillin
- Isonicotinic acid hydrazide (Isoniazid)
- Benzylpenicillin sodium salt
-Itraconazole
- Acyclovir

?Patient was admitted to the infection unit with diagnosis of bacterial dysentery.
On laboratory studies it was revealed that causative element is sensitive to the
many antimicrobial medicines, but patient has anemia. What medicine is contra-
indicated to the patient?
-Enteroseptol
- Phthalazol
+ Levomycetin
-Ampicillin
- Furazolidone

?Microscopy of a smear taken from the film that appeared on the peptone water 23
hours after seeding and culturing of a fecal sample in a thermostat revealed mobile
gram-negative bacteria curved in form of a comma that didn�t make spores or
capsules. What microorganisms were revealed?
+ Vibrios
- Spirochetes
- Clostridia
-Corynebacteria
- Spirilla

?Vomiting matters of a patient suspected of having cholera were delivered to the

bacteriological laboratory. The material was used for preparing a "hanging drop"
specimen. What type of microscopy will be applied for identification of the
causative agent by its mobility?
+ Phase-contrast microscopy
- Electron microscopy
- Immune and electron microscopy
-Fluorescence microscopy
- Immersion microscopy

?Bacilli were extracted from investigated sample. The bacilli are curved, extremely
mobile, gram-negative, form no spores or capsules, have anaerobic form of
respiration. They form transparent smooth colonies in alkaline agar, ferment
saccharose and mannose into acid, produce exotoxin, fibrinolysin, collagenase, and
hyaluronidase. What agent was extracted?
+ Comma bacillus
- Proteus
- Dysentery bacillus
-Blue pus bacillus
- Colibacillus

?Patient with diarrhoea was admitted to the infection unit. Gramnegative curved
rod-like bacteria were founded on bacterioscopic examination of faecal masses What
is the most likely disease in this patient?
-Typhoid fever
+Cholera
- Diphtheria
-Intestinal form of plague
- Salmonellosis gastroenteritis

?6 hours after the initial inoculation of water sample into 1% peptone water, the
growth of a culture in form of a thin pellicle on the medium surface was
registered. Such cultural properties are typical for the causative agent of the
following disease:
+ Cholera
- Plague
- Tuberculosis
-Dysentery
- Pseudotuberculosis

?From the feces of a patient with acute gastroenteritis a pure culture of

microorganisms was obtained. The microorganisms are small mobile slightly curved
gram-negative bacilli that within 6 hours grow into a light blue film on the 1%
alkaline peptone water. Such properties are characteristic of the following
microorganism:
-Bacillus
- Clostridium
- Spirochete
-Spirillum
+ Vibrio

?Initial inoculation of water in 1% peptone water resulted in growth of a thin film

on the medium surface in 6 hours. Such cultural properties are characteristic of
causative agent of the following disesase:
+ Cholera
- Plague
- Tuberculosis
-Dysentery
- Pseudotuberculosis

?After inoculation of feces sample into the 1% alkaline peptonic water and 8- hour
incubation in the thermostat at a temperature of 37oC a culture in form of a tender
bluish film has grown. Such cultural properties are typical for the causative agent
of the following disease:
+ Cholera
- Plague
- Typhoid fever
-Paratyphoid fever A
- Dysentery

?A man is suffering from diarrhea. In summer he spent his vacation in the south at
the sea coast. Bacteria with the following properties were detected in his feces:
gram-negative curved mobile monotrichous bacilli that do not produce spores or
capsules. They are undemanding to nutrient medium but require alkaline reaction (��
8,5-9,5). Described are the agents of the following enteric infection:
+ Cholera
- Shigellosis
- Typhoid fever
-Colienteritis
- Pseudotuberculosis

?A patient had been suffering from profuse diarrhea and vomiting for 2 days. He
died from acute dehydration. Autopsy revealed that the intestinal wall was edematic
and hyperemic, with multiple haemorrhages in the mucous membrane. Intestine lumen
contains whitish fluid resembling of rice water. What disease caused death?
+ Cholera
- Dysentery
- Salmonellosis
-Typhoid fever
- Enterocolitis

?A patient with marked manifestations of exsicosis died in the infectious disease

hospital. Postmortem examination results: the corpse with contracted muscles, dry
skin and mucous membranes, thick and dark blood in veins, edematous plethoric
mucosa, distended bowel loops, the lumen contains about 4 liters of rice-water
fluid. What is the most likely diagnosis?
+ Cholera
- Enteric fever
- Dysentery
-Anthrax, intestinal form
- Yersiniosis

?Autopsy of a 42-year-old man revealed a distinctly dilated lumen of small

intestine filled with rice-water-like liquid. The intestine wall was edematic with
lots of petechial haemorrhages on the mucosa. What infectious disease is the
described enteritis typical for?
+ Cholera
- Dysentery
- Salmonellosis
-Amebiasis
- Typhoid fever

?The disease began acutely. The frequent watery stool developed 6 hours ago. The
body�s temperature is normal. Then the vomiting was joined. On examination: his
voice is hoarse, eyes are deeply sunken in the orbits. The pulse is frequent. Blood
pressure is low. There is no urine. What is the preliminary diagnosis?
+ Cholera
- Toxic food-borne infection
- Salmonellosis
-Dysentery
- Typhoid fever

?A man in grave condition was delivered to the admission ward of a hospital on the
2nd day of illness. Examination revealed body temperature of 36,1oC, sharpened
features of face, dry skin that makes a fold, aphonia, convulsive twitching of some
muscle groups. Acrocyanosis is present. Heart sounds are muffled, Ps is 102 bpm, AP
is 50/20mm Hg. Abdomen is soft, drawn-in, painless. Anuria is present. Stool is
liquid in form of rice water. What is the most probable diagnosis?
+ Cholera
- Acute dysentery
- Salmonellosis
-Escherichiosis
- Intestinal amebiasis

?A child is presumably ill with diphtheria. A specimen of affected mucous membrane

of his pharynx was taken for analysis. The smear was stained and microscopic
examination revealed yellow rods with dark blue thickenings on their ends. What
structural element of a germ cell was revealed in the detected microorganisms?
+ Volutin granules
- Plasmids
- Capsule
-Spores
- Flagella

? On examination of a 6-year-old child the doctor noticed greyish film on the

child�s tonsils. Microscopy of the smear stained by Neisser method detected there
Corynebacterium diphtheria. What morphologic feature was the most indicative for
determining the type of the agent?
-Fence-like position of the agent�s cells
- Spores that exceed cells in diameter
- Localization of the causative agent within macrophages
+ Polar placement of volutin granules
- Presence of the capsule

?A smear from the tonsillar coating of a patient with suspected diphtheria was
found to contain blue bacilli with a thickening at the poles. What method of smear
staining was used?
+ Leffler
- Burri
- Hins
-Gram
- Neisser

?Microscopy of smear preparation stained with methylene blue revealed bacilli with
clublike expansions on their ends similar to -diphtheriae. What additional method
of staining should be used to verify this assumption?
+ Neisser
- Kozlovsky
- Ziehl-Neelsen
-Zdrodovsky
- Aujeszky
?There are several cases of children from boarding school suffering from sore
throat. Microscopy of tonsil smears stained according to Neisser method has
revealed thin yellow bacilli with dark brown grains on their ends placed in the
shape of Roman numeral five. What infection can be suspected in this case?
+ Diphtheria
- Infectious mononucleosis
- Listeriosis
-Tonsillitis
- Scarlet fever

?A sample taken from the pharynx of a patient with angina was inoculated on the
blood-tellurite agar. This resulted in growth of grey, radially striated (in form
of rosettes) colonies up to 4-5 mm in diameter. Microscopically there can be seen
gram-positive rods with club-shaped ends arranged in form of spread fingers.
What microorganisms are these?
+ Corynebacteria diphtheriae
- Clostr. botulinum
- Diphtheroids
-Streptococci
- Streptobacilli

?After inoculation of the material obtained from the pharynx of an angina patient
onto the blood-tellurite agar, grey colonies could be observed. They were 4-5 mm in
diameter, radially striated (in form of rosettes). Microscopical examination
revealed gram-positive bacilli with clavate swollen ends arranged in form of wide-
spread fingers. Identify these microorganisms:
+ Diphtheria corynebacteriae
- Clostr. botulinum
- Diphtheroids
-Streptococci
- Streptobacilli

?Inoculum from pharynx of a patient ill with angina was inoculated into
bloodtellurite agar. It resulted in growth of grey, radially striated (in form of
rosettes) colonies 4-5 mm in diameter. Grampositive bacilli with clublike
thickenings on their ends placed in form of spread wide apart fingers are visible
by microscope. What microorganisms are these?
+ Diphtheria corynebacteriae
- Botulism clostridia
- Diphtheroids
-Streptococci
- Streptobacilli

?A 4-year-old child presents with general weakness, sore throat and deglutitive
problem. After his examination a doctor suspected diphtheria and sent the material
to the bacteriological laboratory. In order to determine the diphtheria causative
agent the material should be inoculated into the following differential diagnostic
medium:
+ Blood tellurite agar
- Levenshtein- Yessen agar
- Ploskyrev�s agar
-Sabouraud�s agar
- Endo�s agar

?From the nasopharynx of a 5-year-old child it was excreted a microorganism which

is identical to Corynebacterium diphtheriae dose according to morphological and
biochemical signs. Microorganism does not produce exotoxin. As a result of what
process can this microorganism become toxigenic?
+ Cultivation in the telluric media
- Chromosome mutation
- Passing through the organism of the sensative animals
-Phage conversion
- Growing with antiserum

?Autopsy of a dead 6-year-old child revealed a marked edema of the soft tissues of
neck and enlarged tonsils. Pharyngeal mucosa was covered with numerous dense
whitish-yellow pellicles exposing deep ulcers after their removal. What infectious
disease caused the death of the child?
+ Diphtheria
- Parainfluenza
- Scarlet fever
-Whooping cough
- �

?While examining a patient an otolaryngologist noticed hyperaemia and significantly

edematous tonsils with a grayish film upon them. Microscopical examination of this
film revealed some gram-positive bacilli placed at an angle with each other. What
disease might be suspected?
+ Diphtheria
- Angina
- Scarlet fever
-Meningococcal nasopharyngitis
- Epidemic parotitis

?During examination of a 6-yearold child a doctor revealed greyish films on the

pharyngeal tonsils. Their removal provoked moderate haemorrhage. Bacterioscopy
revealed gram-positive clublike bacteria. What symptoms will in this child within
the next few days if no specific treatment is provided?
+ Toxic lesions of myocard, liver and kidney
- Pulmonary edema
- Strong paroxysmal cough
-Papulous skinrash
- Intermittent fever

?A diseased child has a high fever, sore throat, swelling of submandibular lymph
nodes. Objectively: pharyngeal mucosa is edematous, moderately hyperemic, the
tonsils are enlarged, covered with grayish membrane tightly adhering to the tissues
above. Attempts to remove the membrane produce the bleeding defects. What disease
are these presentations typical for?
+ Diphtheria
- Catarrhal tonsillitis
- Scarlet fever
-Meningitis
- Measles

?A 5 y.o. girl has high temperature and sore throat. Objectively: soft palate
edema, tonsills are covered with grey films that can be hardly removed and leave
deep bleeding tissue injuries. What disease is the most probable?
+ Pharyngeal diphtheria
- Vincent�s angina
- Lacunar angina
-Infectious mononucleosis
- Necrotic angina

?A woman complains of high temperature to 380C, mild pain in the throat during 3
days. On examination: angle lymphatic nodes of the jaw are 3 cm enlarged, palatinel
tonsils are enlarged and coated with grey plaque which spreads to the uvula and
frontal palatinel arches. What is the most probable diagnosis?
+ Larynx diphtheria
- Infectious mononucleosis
- Vincent�s angina
-Agranulocytosis
- Oropharyngeal candidosis

?A 4-year-old boy had untimely vaccination. He complains of painful swallowing,

headache, inertness, fever. Objectively: the child is pale, has enlarged anterior
cervical lymph nodes, swollen tonsils with cyanotic hyperemia, tonsils are covered
with gray-white pellicles which cannot be easily removed. When the pellicles are
forcibly removed, the tonsils bleed. What is the most likely diagnosis?
+ Oropharyngeal diphtheria
- Lacunar tonsillitis
- Pseudomembranous tonsillitis
-Infectious mononucleosis
- Follicular tonsillitis

?A 24 year old patient complains about general weakness, dizziness, body

temperature rise up to 37,5oC, sore throat, neck edema, enlargement of submaxillary
lymph nodes. Objectively: mucous membrane of oropharynx is edematic and cyanotic,
tonsils are enlarged and covered with films that spread beyond the tonsils and
cannot be easily removed. What is the leading mechanism of this illness�
development?
+ Action of bacterial exotoxin
- Action of bacterial endotoxin
- Allergic
-Accumulation of suboxidated products
- Bacteriemia

?
From pharynx of a child with suspected diphtheria a pure culture of microorganisms
was isolated. Their morphological, tinctorial, cultural and biochemical properties
appeared to be typical for diphtheria causative agents. What study should be
conducted in order to make a conclusion that this is a pathogenic diphtheria
bacillus?
+ Estimation of toxigenic properties
- Estimation of proteolytic properties
- Estimation of urease activity
-Estimation of cystinase activity
- Estimation of ability to decompose starch

?Pure culture of microorganisms was obtained from pharynx of a child with suspected
diphtheria. Morphologic, tinctorial, cultural, and biochemical properties of the
microorganisms were studied and revealed to be characteristic of diphtheria agents.
What investigation should be additionally performed to make a conclusion, that
these microorganisms are pathogenic diphtheria bacilli?
+ Determine toxigenic properties
- Determine proteolytic properties
- Determine urease activity
-Determine cystinase activity
- Determine amylolytic activity

?In order to determine toxigenicity of diphtheria bacilli a strip of filter paper

impregnated with antitoxic diphtheria serum was put on the dense nutrient medium.
There were also inoculated a microbial culture under examination and a strain that
is known to be toxigenic. If the microbial culture under examination produces
exotoxin, this will result in formation of:
+ Precipitin lines
- Precipitin ring
- Haemolysis zones
-Zones of diffuse opacification
- Zones of lecithovitellase activity

?In order to estimate toxogenicity of diphtheria agents obtained from patients the
cultures were inoculated on Petri dish with nutrient agar on either side of a
filter paper strip that was put into the centre and moistened with antidiphtheric
antitoxic serum. After incubation of inoculations in agar the strip-like areas of
medium turbidity were found between separate cultures and the strip of filter
paper. What immunological reaction was conducted?
+ Precipitation gel reaction
- Rings precipitation reaction
- Opsonization
-Coomb�s test
- Agglutination reaction

?When examining a child the dentist found the deposit on both tonsils and suspected
atypical form of diphtheria. A smear was taken, and after the nutrient media
inoculation the toxicity of the isolated pure culture was determined. What reaction
was used to determine the toxigenicity of the isolated strain of diphtheria
bacillus?
+ Gel precipitation reaction
- Agglutination reaction on a glass slide
- Complement binding reaction
-Hemolysis reaction
- Ring precipitation reaction

?A 7 year old girl was taken to an infectious diseases hospital. She had complaints
of high temperature, sore throat, general weakness. A doctor assumed diphtheria.
What will be crucial proof of diagnosis after defining pure culture of pathogenic
organism?
+ Toxigenity test
- Detection of volutine granules
- Hemolytic ability of pathogenic orhanism
-Cystinase test
- Phagolysability

?A 7 y.o. girl was admitted to the infectious diseases hospital with fever, sore
throat, common weakness. A doctor suspected diphtheria. What would be crucial for
diagnosis confirmation after pure culture of causative agent had been singled out?
+ Toxigenity test
- Detection of volutine granules
- Hemolytic ability of a causative agent
-Cystinase test
- Phagolysability

?A patient has pure culture of diphtheria corynebacteria. What immunological

reaction should be used in order to determine bacteria toxigenity?
+ Precipitation in agar
- Agglutination
- Complement binding
-Inhibition of hemagglutination
- Indirect hemagglutination

?In a closed community it is necessary to determine community members immunity to

diphtheria and verify the need for their vaccination. What investigation is
necessary in this case?
-Check medical records for vaccination.
- Test community members for diphtheria bacillus carriage.
+ Determine antitoxin titer by means of indirect hemagglutination
assay.
-Determine diphtheria antibody titer.
- Determine community members immunity to diphtheria bacillus.

?In order to establish the level of antidiphtheritic immunity in a child it was

decided to use a passive hemagglutination test. This task can be completed by the
sensibilization of erythrocytes by:
+ Diphtheria anatoxin
- Diphtheria antitoxin
- Diphtheria bacillus antigens
-Antidiphtheric serum
- �

?A patient with suspected diphtheria went through bacterioscopic examination.

Examination of throat swab revealed rod-shaped bacteria with volutin granules. What
etiotropic preparation should be chosen in this case?
+ Antidiphtheric antitoxic
serum
- Bacteriophage
- Diphtheria antitoxin
-Eubiotic
- Interferon

?Bacterioscopic examination of a smear from the pharynx of a diphtheria suspect

revealed bacilli with volutine granules. What etiotropic drug should be chosen in
this case?
+ Antidiphtheritic antitoxic serum
- Bacteriophage
- Interferon
-Eubiotic
- Diphtheritic anatoxin

?What drugs are used for specific treatment of diphtheria?

-Placental gamma globulin.
- Anatoxin.
- Native plasma.
+ Antitoxic serum.
- Antibiotics.

?A child with diphtheria 10 days after injection of antitoxic antidiphtherial serum

has developed skin rash, accompanied by severe itch, rising temperature up to 380C
and joints pain. What is the cause of these symptoms?
-Delayed type of hypersensitivity
- Anaphylacsis
- Contact allergy
-Atopia
+ Serum sickness

?A 16-year-old adolescent was vaccinated with DTP. In eight days there was
stiffness and pain in the joints, subfebrile temperature, urticarial skin eruption,
enlargement of inguinal, cervical lymph nodes and spleen. What kind of allergic
reaction is observed?
+ Immunocomplex
- Hypersensitivity of immediate type
- Cytoxic
-Hypersensitivity of delayed type
- �
?It is necessary to carry out preventive vaccination of a student group because of
an occurrence of diphtheria. Which preparation should be used for the creation of
the artificial active immunity?
+ Diphtheria anatoxin
- Specific immunoglobulin
- DTP vaccine
-Inactivated bacteria vaccine
- Anti- diphtheria serum

?Vaccination is done by means of a toxin that has been neutralized by a

formaldehyde (0,4%) at a temperature 37 � 400C for four weeks. Ramond was the first
to apply this preparation for diphtheria prophylaxis. What preparation is it?
+ Anatoxin
- Immunoglobulin
- Antitoxic serum
-Adjuvant
- Inactivated vaccine

?Diphtheria exotoxin had been treated with 0,3-0,4% formalin and kept in a
thermostat for 30 days at a temperature of 40o-What preparation was obtained as a
result of these manipulations?
+ Anatoxin
- Antitoxin
- Diagnosticum
-Therapeutic serum
- Diagnostic serum

?A toxin neutralized with 0.4% formaldehyde under 37-40�C for 4 weeks is used for
vaccination. This preparation was first used by Gaston Ramon for diphtheria
prevention. Name this preparation:
-Immunoglobulin
+Anatoxin
- Antitoxic serum
-Inactivated vaccine
- Adjuvant

?An 11-year-old girl has been immunized according to her age and in compliance with
the calendar dates. What vaccinations should the children receive at this age?
+ Diphtheria and tetanus
- TB
- Polio
-Hepatitis B
- Pertussis

?In an inhabited locality there is an increase of diphtheria during the last 3

years with separate outbursts in families. What measure can effectively influence
the epidemic process of diphtheria and reduce the morbidity rate to single cases?
+ Immunization of the population
- Hospitalization of patients
- Detection of carriers
-Early diagnostics
- Disinfection in disease focus

?A bacteriological laboratory received sputum sample of a patient suffering from

tuberculosis. Bacterioscopic examination of smears and detection of tuberculosis
bacillus can be realized by one of enrichment methods that involves processing of
sputum only with solution of caustic soda. What is this method called?
+ Homogenization
- Inactivation
- Flotation
-Filtration
- Neutralization

?Specimen of a patient�s sputum was stained with the following dyes and reagents:
Ziehl�s solution, methylene blue solution, 5% solutoin of sulfuric acid. What
staining method was applied?
+ Ziehl-Neelsen
- Burri�s
- Gram�s
-Peshkov�s
- Neisser�s

?A consumptive patient has an open pulmonary form of disease. Choose what sputum
staining should be selected for finding out the tubercle (Koch�s) bacillus?
+ Method of Ziel-Neelsen
- Method of Romanowsky-Giemsa
- Method of Gram
-Method of Neisser
- Method of Burry-Gins

?Study of bacteriological sputum specimens stained by the Ziel-Neelsen method

revealed some bright-red acid-resistant bacilli that were found in groups or
singularly. When inoculated onto the nutrient media, the signs of their growth show
up on the 10-15 day. These bacteria relate to the following family:
+ Micobacterium tuberculosis
- Yersinia pseudotuberculosis
- Histoplasma dubrosii
-Klebsiella rhinoscleromatis
- Coxiella burnettii
?Microscopy of stained (Ziehl-Neelsen staining) smears taken from the sputum of a
patient with chronic pulmonary disease revealed red bacilli. What property of
tuberculous bacillus was shown up?
+ Acid resistance
- Alkali resistance
- Alcohol resistance
-Capsule formation
- Sporification

?A bacteriological laboratory has received smears from the sputum of a patient with
a chronic pulmonary disease. Microscopical examination of the smears stained by the
Ziehl-Neelsen technique revealed red bacilli. What property of the tuberculosis
bacillus has shown itself?
+ Acid resistance
- Alkali resistance
- Alcohol resistance
-Capsule formation
- Spore formation

?Sputum smears of a patient with chronic pulmonary disease were stained by Ziehl-
Neelsen method and analyzed in the bacteriological laboratory. Microscopy revealed
red bacillus. What property of tuberculosis myobacteria was found?
+ Acid resistance
- Alkali resistance
- Alcohol resistance
-Encapsulation
- Spore-formation

?During the skill-building session in microbiology the students need to stain the
prepared and fixed sputum smears obtained from a tuberculosis patient. What
staining technique should be used in this case?
-Gram
- Giemsa
+ Ziehl-Neelsen
-Burry
- Gins

?While registering the child to the school Mantoux's test was made to define
whether revaccination was needed test result is negative. What does this result of
the test mean?
+ Absence of antitoxic immunity to the tuberculosis
- Presence of antibodies for tubercle bacillus
- Absence of antibodies for tubercle bacillus
-Presence of cell immunity to the tuberculosis
- Absence of cell immunity to the tuberculosis

?A child entering the school for the first time was given Mantoux test in order to
determine if there was a need for revaccination. The reaction was negative. What is
the meaning of this test result?
+ No cell-mediated immunity to tuberculosis
- Availability of cell-mediated immunity to tuberculosis
- No antibodies to the tuberculosis bacteria
-No anti-toxic immunity to tuberculosis
- Presence of antibodies to the tuberculosis bacteria

?A 45 year old male died from disseminated tuberculosis. On autopsy the symptoms of
tuberculosis were confirmed by both microscopical and histological analyses. What
kind of hypersensitivity reaction underlies the process of granuloma development?
+ Delayed
- Antibody- dependent cytotoxicity
- Complement- dependent cytotoxicity
-Anaphylactic
- Immune Complex

?hours after performing tuberculin test (Mantoux test) to a child a 10 mm papule

appeared on the spot of tuberculin introduction. What hypersensitivity mechanism
underlies these changes?
+ Cellular cytotoxicity
- Anaphylaxis
- Antibody-dependent cytotoxicity
-Immune complex cytotoxicity
- Granulomatosis

?Tuberculine was injected intracutaneously to the child for tuberculin test. Marked
hyperemia, tissue infiltration developed on the place of injection in 24 hours.
What mechanism caused these modifications?
+ Cells cytotoxity
- Reagin type cytotoxity
- Granuloma formation
-Immunocomplex cytotoxity
- Antibody cytotoxity

?A 4 year old child had Mantoux test. 60 hours after tuberculin introduction a
focal skin hardening and redness 15 mm in diameter appeared. It was regarded as
positive test. What type of hypersensitivity reaction is this test based upon?
+ Delayed-type hypersensitivity
- Immune complex- mediated hypersensitivity
- Complement- mediated cytotoxic hypersensitivity
-Immediate hypersensitivity
- �

?A 10-year-old child had the mantoux tuberculin test administered. 48 hours later a
papule up to 8 mm in diameter appeared on the site of the injection. What type of
hypersensitivity reaction developed after the tuberculin injection?
+ Type IV hypersensitivity reaction
- Arthus phenomenon
- Seroreaction
-Type II hypersensitivity reaction
- Atopic reaction

?A 10 year old child was subjected to Mantoux test (with tuberculin). 48 hours
later a papule up to 8 mm in diameter appeared on the site of tuberculin injection.
What type of hyperesponsiveness reaction has developed after tuberculin injection?
+ Hyperresponsiveness reaction type IV
- Reaction of Arthus phenomenon type
- Reaction of serum sickness type
-Atopic reaction
- Hyperresponsiveness reaction type II

?A child suspected for tuberculosis underwent Mantoux test. 24 hours after allergen
injection there appeared a swelling, hyperaemia and tenderness. What are the main
components in the development of this reaction?
+ Mononuclears, T-lymphocytes and lymphokines
- Granulocytes, T-lymphocytes and IgG
- Plasmatic cells, T-lymphocytes and lymphokines
-B-lymphocytes, IgM
- Macrophages, B-lymphocytes and monocytes

?A patient was diagnosed with active focal pulmonary tuberculosis. What drug should
be prescribed in the first place?
+ Isoniazid
- Sulfalen
- Cyclocerine
-Ethionamiden
- Ethoxide

?A patient suffers from pulmonary tuberculosis. During treatment neuritis of visual

nerve arose. What drug has caused this by-effect?
+ Isoniazid
- Ethambutol
- Kanamycin
-Rifampicin
- Streptomycin

?After 4 months of treatment for tuberculosis the patient began complaining of toes
and fingers numbness, sensation of creeps. He was diagnosed with polyneuritis. What
antituberculous drug might have caused these complications?
+ Isoniazid
- Rifampicin
- Ciprofloxacin
-Sodium salt of benzylpenicillin
- Iodine solution

?A patient suffering form tuberculosis was treated with rifampicin, which caused
drug resistance of tuberculosis mycobacteria. In order to reduce mycobacteria
resistance, rifampicin should be combined with the following drug:
+ Isoniazid
-Acyclovir
-Intraconazole
-Metronidazole
-Amoxicillin

?Tuberculosis can be treated by means of combined chemotherapy that includes

substances with different mechanisms of action. What antituberculous medication
inhibits transcription of RNA into DNA in mycobacteria?
+ Rifampicin
- Isoniazid
- Streptomycin
-Ethionamide
- Para-aminosalicylic acid

?A patient with pulmonary tuberculosis is prescribed the most effective

antituberculosis antibiotic. Name this drug:
-Tetracycline
- Furasolidone
+ Rifampicin
-Bactrim (Co- trimoxazole)
- Streptocide

?The 32-year-old patient has been taking antituberculosis drugs. Later he noticed
that his urine had become redorange in color. What drug is conductive to this
phenomenon?
+ Rifampicin
- Isoniazid
- Pyrazinamide
-Ethambutol
- Streptomycin sulphate

?After starting treatment for pulmonary tuberculosis a patient complained about red
tears and urine. What drug could cause such changes?
+ Rifampicin
- Benzylpenicillin sodium salt
- Benzylpenicillin potassium salt
-Biseptol-480
- Cefazolin

?To treat tuberculosis, an antibiotic that colors urine red is prescribed. Name the
antibiotic:
-Amoxicillin
+Rifampicin
- Nitroxoline
-Erythromycin
- Cefotaxime 53

?Following treatment with a highly efficient anti-tuberculosis drug a 48-yearold

female developed optic nerve neuritis, memory impairment, cramps. Which of these
anti-TB drugs had the patient taken?
+ Isoniazid
- PASA
-Rifampicin
-Ethambutol
- Kanamycin

?A patient being treated for tuberculosis is suffering from hearing deterioration.

What drug causes this complication?
+ Streptomycin
- Isonicotinic acid hydrazide (Isoniazid)
- Rifampicin
-Ethionamide
- Kanamycin sulphate

?A 16 y.o. boy from a countryside entered an educational establishment. Scheduled

Manteux test revealed that the boy had negative reaction. What are the most
reasonable actions in this case?
+ To perform BCG vaccination
-To repeat the reaction in a month
- To perform serodiagnostics of tuberculosis
-To isolate the boy temporarily from his mates
- To perform rapid Price diagnostics

?Medical examination of the first-year pupils included Mantoux test. 15 pupils out
of 35 had negative reaction. What actions should be taken against children with
negative reaction?
+ BCG vaccination
- Examination of blood serum
- Rabies vaccination
-Repeat Mantoux test
- Antitoxin vaccination

?Planned mass vaccination of all newborn 5-7 day old children against tuberulosis
plays an important role in tuberculosis prevention. In this case the following
vaccine is applied:
+ BCG
- Diphteria and tetanus toxoids and pertussis vaccine
- Diphtheria and tetanus anatoxin vaccine
-Adsorbed diphtheria vaccine
- �

?For tuberculosis prevention the newborns got an injection of a vaccine. What

vaccine was used?
+ BCG
- Mantoux
- DTaP vaccine
-Anatoxin
- Oral polio vaccine (Sabin vaccine)

?In a maternity hospital a newborn should receive vaccination against tuberculosis.

What vaccine should be chosen?
+ BCG vaccine
- STI vaccine
- EV vaccine
-DPT vaccine
- Tuberculin

?There is a suspicion of active tuberculosis development in patient. The doctor has

appointed Mantoux test to make a diagnosis. What immunobiological agent has to be
administered?
+ Tuberculine
- BCG vaccine
- DPT vaccine
-Tularin test
- DT vaccine

?A 6-year-old child with suspected active tuberculosis process has undergone

diagnostic Mantoux test. What immunobiological preparation was injected?
+ Tuberculin
- BCG vaccine
- DTP vaccine
-Tularinum
- Td vaccine

?The first grade pupils were examined in order to sort out children for
tuberculosis revaccination. What test was applied for this purpose?
+ Mantoux test
- Schick test
- Anthraxine test
-Burnet test
- Supracutaneous tularin test

?First-year schoolchildren have received tuberculin skin test (Mantoux test) at the
school nurse�s office. The purpose of this test was:
-To detect parotitis in schoolchildren
- To measure allergization rate toward rickettsia
- To measure immune stress toward diphtheria
+ To determine the children that need to receive BCG vaccination
- To preventively vaccinate against tuberculosis

?Microscopic analysis of tissue sampling from affected area of mucous membrane of

oral cavity revealed bacillus in form of accumulations that looked like a pack of
cigarettes. Ziehl-Neelsen staining gives them red colour. What kind of pathogenic
organism was most likely revealed in tissue sampling?
+ M.leprae
- M. tuberculosis
- A bovis
-A israilii
- M. avium

?Granulomas containing lymphocytes and macrophages were detected during analysis of

skin biopsy material. Among macrophages there are large cells with fat inclusions,
which contain microorganisms in spheric packages (Virchow�s cells). The following
disease is based on the described type of hypersensitivity:
+ Leprosy
- Syphilis
- Tuberculosis
-Rhinoscleroma
- Epidemic typhus

?A patient presents with fever, chill and cough. From his sputum the ovoid Gram-
negative bipolar-stained bacilli with a delicate capsule were secured. What is the
most likely diagnosis?
+ Plague
- Tuberculosis
- Leptospirosis
-Brucellosis
- Toxoplasmosis

?2 days after a hunter cut a ground squirrel�s body, he developed fever up to 38 C,

his lymph nodes enlarged. Later he developed pneumonia with serohemorrhagic exudate
that contained egg-shaped microorganisms with bipolar staining. What provisional
diagnosis can be made in this case?
-Brucellosis.
- Anthrax.
- Tetanus.
+ Plague.
- Pseudotuberculosis.

?During the examination of a patient, who had been to the mountain pasture and had
been hospitalized in a bad condition with fever, the doctor found out the
enlargement of inguinal lymph nodes to 8 cm, which were attached to the surrounding
tissues, immovable, the skin above them was red and tender. The microscopic
examination of the node revealed acute serohemorrhagic inflammation. What disease
is it typical for?
-Brucellosis
- Syphilis
- Anthrax
-Tularemia
+ Plague

?The patient has developed pain in the axillary area, rise of temperature developed
10 hours ago. On examination: shaky gait is marked, the tongue is coated by white
coating. The pulse is frequent. The painful lymphatic nodules are determined in the
axillary area. The skin is erythematous and glistering over the lymphatic nodules.
What is the most probable diagnosis?
+ Bubonic plague
- Acute purulent lymphadenitis
- Tularemia
-Anthrax
- Lymphogranulomatosis

?
A patient has got pain in the axillary area, rise of temperature developed 10 hours
ago. On examination: shaky gait is evident, the tongue is coated with white
deposit. The pulse is frequent. The painful lymphatic nodes are revealed in the
axillary area. The skin over the lymph nodes is erythematous and glistering.What is
the most probable diagnosis?
+ Bubonic plague
- Acute purulent lymphadenitis
- Lymphogranulomatosis
-Anthrax
- Tularemia

?A 45-year-old patient, a sailor, was hospitalized on the 2nd day of the disease. A
week ago he returned from India. Complains of body temperature of 41oC, severe
headache, dyspnea, cough with frothy rusty sputum. Objectively: the patient is
pale, mucous membranes are cyanotic, breathing rate - 24/min, tachycardia is
present. In lungs: diminished breath sounds, moist rales over both lungs,
crepitation. What is the most likely diagnosis?
+ Pneumonic plaque
- Miliary tuberculosis
- Influenza
-Ornithosis
- Sepsis

?The laboratory for especially dangerous infections conducts microscopic

examination of pathological material from a patient with suspected plague. The
sample was stained by Burri-Gins technique. What property of the causative agent
can be identified by this technique?
+ Capsule formation
- Spore formation
- Acid resistance
-Alkali resistance
- Presence of volutin Granules
?A puncture sample has been taken from the inguinal lymph nodes of a patient
provisionally diagnosed with plague. The sample was inoculated into a hard nutrient
medium. What shape will the colonies have, if the diagnosis is confirmed?
-�Dewdrops�
- �Shagreen leather�
+ �Lace handkerchief�
-�Mercury drops�
- �Lion�s mane�

?Dwellers of a village noticed mass mortality of rats in some farms. It was

suspected that the animals might have died from plague. What postmortal analyses
should be conduced in order to establish the causative agent of the infection as
soon as possible?
+ Ring precipitation reaction
- Agglutination reaction
- Passive agglutination reaction
-Neutralization reaction
- Complement- binding reaction

?On the territory of a certain region the mass death of rodents was observed. It
was assumed that it may be caused by plague agent. What serological reaction should
be applied for quick determination of antigen of this epizootic agent?
+ Precipitation reaction
- Agglutination reaction
- Reaction of passive hemagglutination
-Bordet-Gengou test
- Neutralization reaction

?On a certain territory mass death of rodents was registered. It was suspected that
their death might have been caused by plague. What serological reaction should be
applied for quick identification of antigen of the causative agent of this
epizooty?
+ Precipitation
- Agglutination
- Passive hemagglutination
-Complement binding
- Neutralization

?On examination of a patient with disease onset 5 days ago the doctor suspected
tularemia and prescribed the patient tularin intracutaneously. What is the purpose
of this drug administration in the patient?
+ Allergy diagnostics
- Prognosis for the disease
- Treatment
-Treatment evaluation
- Prevention

?A smear of streptobacillus preparation stained by Ozheshko method has been studied

microscopically with oil immersion. What structural feature of the bacteria has
been studied?
+ Spores
- Capsule
- Flagella
-Inclusions
- Structure of cell wall

?It is planned to use the territory of an old cattle burial ground (which is not
used for more than 50 years) for building houses. But ground analysis revealed
presence of the pathogen of the very dangerous illness. Which of the indicated
microorgonisms is likely to remain in the ground for such a long time?
-Mycobacterium bovis
- Brucella abortus
- Yersinia pestis
-Francisella tularensis
+ Bacillus anthracis

?The territory of an old burial ground for animal refuse that hasn�t been used for
over 50 years is meant for house building. But soil investigation showed the
presence of viable spores of a causative agent causing a very dangerous disease.
What microorganism might have been preserved in soil for such a long period of
time?
+Bacillus anthracis
- Francisella tularensis
- Brucella abortus
-Yersinia pestis
- Mycobacterium bovis

?A patient complained about a carbuncle on his face. Examination results: neither

dense nor painful edema of subcutaneous cellular tissue, there is black crust in
the middle of the carbuncle and peripheral vesicular rash around it.
Bacteriological examination revealed presence of immobile streptobacilli able of
capsulation. What microorganisms are causative agents of this disease?
+ Bacillus antracis
- Staptylococcus aureus
- Bacillus anthracoides
-Bacillus megaterium
- Bacillus subtilis

?A 34 year old male patient consulted a doctor about face carbuncle. Objectively: a
loose, painless edema of hypodermic tissue; black crust in the center of carbuncle,
vesicular rash around it. Microbiological examination revealed static
streptobacilli capable of capsule building. What microorganisms are the causative
agents of this disease?
+ Bacillus antracis
- Staptylococcus aureus
- Bacillus subtilis
-Bacillus anthracoides
- Bacillus megaterium

?A worker of a cattle farm consulted a surgeon about fever up to 40oC, headache,

weakness. Objective examination of his back revealed hyperaemia and a dark red
infiltration up to 5 cm in diameter with black bottom in the center and some
pustules. What disease are these presentations typical for?
+ Anthrax
- Plaque
- Tularemia
-Furuncle
- Abscess

?A 43 y.o. patient was admitted to the hospital with complaints of high temperature
of the body and severe headache. On examination: carbuncle is revealed on the
forearm. There are intense edema around it, insignificant pain, regional
lymphadenitis. The patient is a worker of cattle-ranch. What disease is it
necessary to think about first?
+ Anthrax
- Carcinoma of skin
- Erysipelas
-Erysipeloid
- Eczema

?
A 49-year-old countryman got an itching papule on the dorsum of his right hand. In
the centre there is a vesicle with serosanginous exudate. Within the next days the
patient developed a painless edema of hand and forearm. On the 4th day the
temperature rose to 38,5oC, in the right axillary region a large painful lymph node
was found. One daybefore the onset of the disease the patient had examined a dead
calf. What is the most likely diagnosis?
+ Cutaneous anthrax
- Bubonic plague
- Lymphocutaneous tularemia
-Carbuncle
- Erysipelas

?Quite often, the soil may contain a number of pathogenic microorganisms. The
causative agents of the following disease may exist in the soil for a long time:
+ Anthrax
- Diphtheria
- Viral hepatitis
-Pertussis
- Dysentery

?At a bacteriological laboratory animal skins are analyzed by means of Ascoli

precipitaion test. What is detected if the reaction is positive?
+ Anthrax agent antigens
- Brucellosis agent
- Anaerobic infection toxin
-Plague agent
- Yersinia surface Antigen

?What diagnostic method should be used in industry to test the raw leather for
presence of - antracis?
-Microscopy with Burry-Gins stain
- Microscopy with Aujeszky stain
+ Ascoli's thermo precipitation test
-Bacteriological analysis
- Serological test

?There was a record of some anthrax cases among animals in a countryside. The
spread of disease can be prevented by means of immunization. What kind of vaccine
should be used?
+ STI live vaccine
- BCG vaccine
- Salk vaccine
-Sabin�s vaccine
- Diphteria and tetanus toxoids and pertussis vaccine

?In a village, a case of anthrax had been registered. Medical services began
epidemiologically indicated specific prophylaxis of population against anthrax.
What preparation was used for this purpose?
+ Live vaccine
- Inactivated vaccine
- Chemical vaccine
-Genetically engineered vaccine
- Anatoxin

?An infectious diseases hospital admitted a veterinarian with assumed brucellosis.

What serologic test can confirm this diagnosis?
+ Wright�s agglutination reaction
- Widal�s agglutination reaction
- Ascoli�s precipitation reaction
-Weigl�s agglutination reaction
- Wassermann reaction of complement binding

?A veterenary attendant working at a cattle farm complains of joint pain, fever,

indisposition and sweating at nighttime that he has been experiencing for a month.
Giving the regard to such presentations and occupational history the doctor
suspected brucellosis. What material taken from this patient is to be analyzed in a
common microbiological laboratory?
+ Blood serum
- Spinal fluid
- Vomit mass
-Urine
- Feces

?A 40-year-old female farmworker has been diagnosed with brucellosis and

administered causal chemotherapy. What group of drugs will be used for this
purpose?
+ Antibiotic
- Donor immunoglobulin
- Inactivated therapeutic vaccine
-Antitoxic serum
- Polyvalent bacteriophage

?For cultivation of Brucella, pure cultures should be incubated in CO2 enriched

atmosphere. What type of breathing is typical for Brucella?
+ Capnophilic
- Facultative anaerobic
- Obligate anaerobic
-Obligate aerobic
- Any

?Microscopic examination of a microbial culture revealed fusiform spore-forming

microorganisms that get violet-blue Gram�s stain. What microorganisms were
revealed?
+ Clostridia
- Streptococci
- Spirochaete
-Actinomycete
- Diplococci

?Those organisms which in the process of evolution failed to develop protection

from H2O2 can exist only in anaerobic conditions. Which of the following enzymes
can break hydrogen peroxide down?
+ Peroxidase and catalase
- Oxygenase and hydroxylase
- Cytochrome oxidase, cytochrome B5
-Oxygenase and catalase
- Flavin- dependent oxidase

?Pathological material taken from a patient suffering from pulpitis was inoculated
onto Kitt-Tarozzi cultural medium. It is planned to find the following
microorganisms:
+ Anaerobic
- Acid-resistant
- Acidophilic
-Haemolytic
- Aerobic

?A patient was taken to a hospital with acute food poisoning caused by homemade
canned mushrooms. The product analysis revealed some microorganisms that develop
only in the absence of oxygen. What microorganisms caused the poisoning?
+ Obligate anaerobes
- Facultative anaerobes
- Microaerophiles
-Obligate aerobes
- Capnophiles

?A lot of pyoinflammatory processes in oral cavity are caused by anaerobes. What

nutrient medium can be used for control of wound textile contamination by
anaerobes?
+ Kitt-Tarozzi
- Endo
- Roux
-Sabouraud�s
- Ploskirev�s

?A patient has a necrotizing phlegmon of his lower extremity. A doctor suspects a

gas gangrene. Microscopy reveals grampositive bacilli. In order to confirm the
diagnosis further bacteriological tests should include inoculation of the material
into the following nutrient medium:
+ Kitt-Tarozzi medium
- Endo agar
- Meat-peptone agar
-Levine agar
- Milk-salt agar

?In 8 days after a surgery the patient develops tetatus. The surgeon suspects this
condition to be caused by suture material contaminated by tetanus agent. The
material is delivered to a bacteriological laboratory. What nutrient medium is
required for primary inoculation of the suture material?
-Sabouraud agar
- Endo agar
- Hiss medium
+ Kitt-Tarozzi medium
- Egg-yolk salt agar

?A patient consulted a dentist about limited (restricted) mouth opening (trismus)

He has a history of a stab wound of the lower extremity. What infection may cause
these symptoms?
+ Tetanus
- Brucellosis
- Whooping cough
-Wound anaerobic infection
- Tularemia

?A patient with convulsive contractions of facial muscles was admitted to the

infectious disease ward. From a scratch on his lower right extremity analysts
isolated bacteria with terminal endospores that gave them drumstick appearance.
What bacteria are compliant with given description?
+ Clostridium tetani
- Clostridium botulinum
- Clostridium perfringens
-Bacillus anthracis
- Bacillus cereus
?A 47-year-old male patient consulted a dentist about difficult mouth opening
(lockjaw or trismus). The patient has a history of a stab wound of the lower
extremity. What infection can be manifested by these symptoms?
+ Tetanus
- Brucellosis
- Whooping cough
-Anaerobic wound infection
- Tularemia 65

?On the 15-th day after a minor trauma of the right foot a patient felt malaise,
fatigability, irritability, headache, high body temperature, feeling of
compression, tension and muscular twitching of his right crus. What disease can it
be?
+ Tetanus
- Anaerobic gas gangrene
- Erysipelas
-Acute thrombophlebitis
- Thromboembolism of popliteal artery

?A 65 y.o. woman complains of complicated mouth opening following foot trauma 10

days ago. Next day she ate with difficulties, there were muscles tension of back,
the back of the head and abdomen. On the third day there was tension of all muscle
groups, generalized convulsions every 10-15 min. What is the most probable
diagnosis?
+ Tetanus
- Tetania
- Meningoencephalitis
-Hemorrhagic stroke
- Epilepsy

?A 45-year-old patient complains of body temperature rise up to 40oC, general

weakness, headache, painfulness and spastic muscle contractions around the wound in
the shin. He received this wound 5 days ago when working in his garden. He
requested no medical care back then. What wound infection can be suspected?
+ Tetanus
- Anthrax
- Erysipelas
-Gram-positive
- Gram-negative

?A 45-year-old patient complains of fever up to 40oC, general weakness, headache

and spasmodic contraction of muscles in the region of a shin wound. The patient got
injured five days ago when tilling soil and didn�t seek medical attention. What
kind of wound infection can be suspected?
+ Tetanus
- Anthrax
- Erysipelas
-Gram-positive
- Gram-negative

?A 38-year-old male complains of tonic tension of the masticatory muscles, so that

he cannot open his mouth. 12 days before, he was bitten by an unknown dog.
Objectively: there is pronounced tension and twitching of the masticatory muscles.
What is the most likely diagnosis?
+ Tetanus
- Rabies
- Hysteria
-Neuralgia
- Apyretic tetanus
?Soil microflora often includes the representatives of pathogenic microorganisms.
Specify the diseases, whose causative agents may say viable in the soil for a long
time:
+ Tetanus and gas anaerobic infection
- Tuberculosis and mycobacterioses
- Colibacillosis and cholera
-Leptospirosis and plague
- Typhoid fever and dysentery

?What preventive medications should be injected to a patient with open

maxillofacial trauma provided that he has never got prophylactic vaccination
before?
+ Antitetanus immunoglobulin and anatoxin
- Diphtheria, tetanus toxoids and pertussis vaccine and antibiotics
- Anticonvulsive drugs and anatoxin
-Antitetanus serum and antibiotics
- Tetanus anatoxin and antibiotics

?Anti-tetanus gamma globulin is produced by hyperimmunization of donors with

tetanus anatoxin. What class of immunoglobulins prevails in this preparation?
+ IgG
- IgA
- IgM
-IgE
- IgD

?On the 8th day since the patient was inoculated with antitetanic serum because of
dirty wound of his foot he has developed rising temperature up to 38� , pains in
the joints, rash and itch. The blood tests revealed leukopenia and
thrombocytopenia. Allergic reaction of what type has developed in this case?
-Anaphylactic
- Cytotoxic
- Delayed type of hypersensitivity
-Stimulating
+ Immunocomplex

?A 16-year-old adolescent was vaccinated with DTP. In eight days there was
stiffness and pain in the joints, subfebrile temperature, urticarial skin eruption,
enlargement of inguinal, cervical lymph nodes and spleen. What kind of allergic
reaction is observed?
+ Immunocomplex
- Hypersensitivity of immediate type
- Cytoxic
-Hypersensitivity of delayed type
- � 67

?A child cut his leg with a piece of glass while playing and was brought to the
clinic for the injection of tetanus toxoid. In order to prevent the development of
anaphylactic shock the serum was administered by Bezredka method. What mechanism
underlies this method of desensitization of the body?
+ Binding of IgE fixed to the mast cells
- Blocking the mediator synthesis in the mast cells
- Stimulation of immune tolerance to the antigen
-Stimulation of the synthesis of antigenspecific IgG
- Binding of IgE receptors to the mast cells

?A 10-year-old child cut his leg with a piece of glass and was sent to a clinic for
an anti-tetanus serum injection. In order to prevent the development of
anaphylactic shock, the Besredka desensitization method was applied. What mechanism
underlies this method?
+ Binding to IgE fixed to mast cells
- Inhibited synthesis of mast cells mediators
- Stimulation of the immunological antigen tolerance
-Stimulation of antigen-specific IgG2 synthesis
- Binding of IgE receptors on mast cells.

?A 10-year-old child cut his leg with a glass shard, when playing, and was
delivered to outpatient department to receive anti-tetanus serum. To prevent
development of anaphylactic shock the serum was introduced by Bezredka method. This
method of organism hyposensitization is based on the following mechanism:
-Stimulation of antigen-specific IgG2
- Stimulation of the immunological antigen tolerance
- Stabilization of mast cell membranes
-Blocking of mast cell mediators synthesis
+ Binding of mast cell-fixed IgE

?Typical manifestations of food poisoning caused by - botulinum are double vision,

abnormal functioning of the swallowing and breathing. These symptoms develop as a
result of:
+ Exotoxin effects
- Enterotoxin effects
- Enterotoxic shock development
-Activation of adenylate cyclase
- Pathogen adhesion to the enterocyte receptors

?Typical signs of food poisoning caused by - botulinum include diplopia, swallowing

and respiration disorders. These signs develop due to:
-Enterotoxic shock development
- Enterotoxin action
C Adenylate cyclase activation
-Adhesion of the agent to enterocyte receptors
+ Exotoxin action

?After consumption some tinned meat a patient had diplopia, acute headache,
deglutition disorder, hard breathing, muscle weakness. The diagnosis was botulism.
What factor of pathogenicity are the clinic presentations of this disease connected
with?
+ Exotoxin
- Hemolysin
- Endotoxin
-Plasmocoagulase
- Fibrinolysin

?When examining a patient with a suspicion of food toxicoinfection, a doctor on

duty has detected symptoms characteristic of botulism. The patient named the meals
he had eaten the day before. What is the most probable cause of infection?
+ Homemade canned meat
- Custard pastry from private bakery
- Sour cream from local dairy factory
-Strawberries from suburban vegetable garden
- Fried eggs

?When examining a patient presumptively diagnosed with food toxicoinfection, a

doctor on duty has detected symptoms characteristic of botulism. The patient named
the meals he ate the day before. What is the most probable cause of infection?
+ Homemade canned meat
- Custard pastry from a private bakery
- Sour cream from a local dairy factory
-Strawberries from a suburban vegetable garden
- Fried eggs

?
An outbreak of food poisoning was recorded in an urban settlement. The illness was
diagnosed as botulism on the grounds of clinical presentations. What foodstuffs
should be chosen for analysis in the first place in order to confirm the diagnosis?
+ Tinned food
- Potatoes
- Pasteurized milk
-Boiled meat
- Cabbage

?A bacteriological laboratory studied the home-made dried fish which had caused a
severe food poisoning. Microscopy of the culture grown on the Kitt-Tarozzi medium
revealed microorganisms resembling a tennis racket. What is the most likely
diagnosis?
+ Botulism
- Salmonellosis
- Cholera
-Dysentery
- Typhoid fever

?A bacteriological laboratory has been investigating a sample of homemade dried

fish that was the cause of severe food poisoning. Microscopy of the culture
inoculated in Kitt-Tarozzi medium revealed microorganisms resembling a tennis
racket. What diagnosis can be made?
+ Botulism
- Salmonellosis
- Cholera
-Dysentery
- Typhoid fever

?
A bacteriological laboratory received a sample of dried fish from an outbreak of
food poisoning. Inoculation of the sample on Kitt-Tarozzi medium revealed
microorganisms resembling tennis racket. These microorganisms are causative agents
of the following disease:
+ Botulism.
- Diphtheria.
- Typhoid fever.
-Salmonellosis.
- Dysentery.

?On microscopic examination of leftovers of the canned meat eaten by patient with
severe food toxicoinfection the following was detected: gram-positive bacilli with
subterminal staining defect and configuration alteration of bacilli generally
resembling a tennis racket. What agent was detected?
+ +botulinum
- P.vulgaris
- E coli
-S.aureus
- S.enteritidis

?Botulism agent causes severe food toxicoinfection. Point out the most
characteristic morphologic feature of botulism agent.
+ Gram-positive spore-forming bacilli with subterminal spore
- Thick gram-positive non-sporeforming bacilli
- Gram-positive spore-forming bacilli with terminal spore
-Thin mobile spore-forming bacilli with central spore
- Thick gram-positive non-sporeforming bacilli

?The causative agent of botulism causes severe food poisoning. Specify the most
characteristic morphological feature of botulism causative agent:
+ Gram-positive bacillus with subterminal spore
- Thick gram-positive non-spore-forming bacillus
- Gram-positive bacillus with terminal spore
-Thin mobile bacillus with central spore
- Thick gram-positive bacillus without spores and flagella

?The patient 25 y.o. was admitted on the 1st day of the disease with complaints of
double vision in the eyes, heavy breathing. The day before the patient ate homemade
mushrooms. On objective examination: paleness, widened pupils, disorder of
swallowing, bradycardia, constipation are marked. What is the diagnosis?
+ Botulism
- Yersiniosis
- Leptospirosis
-Salmonellosis, gastrointestinal form
- Lambliasis

?In the morning a patient had nausea, abdominal discomfort, single vomiting, dry
mouth. In the evening, the patient presented with the increasing general weakness,
double vision, difficult swallowing of solid food. Objectively: ptosis, mydriasis,
anisocoria, absence of gag and pharyngeal reflex, dry mucous membranes. The
previous evening the patient had dinner with canned food and alcohol. What is the
presumptive diagnosis?
+ Botulism
- Poliomyelitis
- Food toxicoinfection
-Acute ischemic stroke
- Intoxication with unknown poison

?A 12-year-old boy presents with nausea, frequent repeated vomiting that first
occurred after eating canned vegetables. Objectively: the patient has dry mucous
membranes, muscular hypotonia, anisocoria, mydriasis, dysphagia and dysarthria.
What is the most likely diagnosis?
+ Botulism
- Shigellosis
- Salmonellosis
-Cholera
- Yersiniosis

?Patient with vomiting, dizziness, sensation of dubble vision, difficult swallowing

was admitted to the hospital. Doctor suspects botulism. What diagnostic methods
should be used for diagnosis approving?
-�
- Bacteriological, mycological
+ Biological test, bacteriological
-Allergic test, serological
- Protozoological, microscopical

?A patient has been hospitalized with provisional diagnosis of botulism. What

serological reaction should be used to reveal botulinum toxin?
+ Neutralization reaction
- Agglutination reaction
- Bordet-Gengou test
-Precipitation reaction
- Immunofluorescence test

?Researchers of a bacteriological laboratory examine tinned meat for botulinic

toxin. For this purpose a group of mice was injected with an extract of the
material under examination and antitoxic antibotulinic serum of A, B, E types. A
control group of mice was injected with the same extract but without antibotulinic
serum. What serological reaction was applied?
+ Neutralization
- Precipitation
- Complement binding
-Double immune diffusion
- Opsonocytopha-gic

?A laboratory received a food product that had been taken from the focus of food
poisoning and presumably contained botulinum toxin. To identify the type of toxin,
the neutralization reaction must be performed on white mice. What biological
product is used in this reaction?
+ Antitoxic serum
- Normal serum
- Antibacterial serum
-Diagnosticum
- Allergen

?Bacteriological laboratory examines canned meat whether it contains botulinum

toxin. For this purpose an extract of test specimen and antitoxic antibotulinic
serum of A, B, E types were introduced to a group of mice under examination; a
control group of mice got the extract without antibotulinic serum. What serological
reaction was applied?
+ Neutralization
- Precipitation
- Complement binding
-Double immune diffusion
- Opsonophagocytic

?A bacteriological laboratory tests canned meat for botulinum toxin. Extract of the
tested material and ABE botulinum antitoxin serum was introduced into the test
group of mice; a control group of mice received the extract without antibotulinic
serum. What serological reaction was used?
+ Neutralization
- Precipitation
- Complement binding
-Double immunodiffusion
- Opsonophagocytic

?A 12 year old girl complains about abrupt weakness, nausea, dizziness, vision
impairment. The day before she ate home-made stockfish, beef. Examination revealed
skin pallor, a scratch on the left knee, dryness of mucous membranes of oral
pharynx, bilateral ptosis, mydriatic pupils. The girl is unable to read a simple
text (mist over the eyes). What therapy would be the most adequate in this case?
+ Parenteral introduction of polyvalent antibotulinic serum
- Parenteral disintoxication
- Parenteral introduction of antibiotics
-Gastric lavage
- Parenteral introduction of antitetanus serum

?A patient diagnosed with botulism has been prescribed antibotulinic serum for
treatment. What immunity will be formed in the given patient?
+ Antitoxic passive immunity
- Infection immunity
- Antitoxic active immunity
-Antimicrobic active immunity
- Antimicrobic passive immunity

?A patient has food poisoning. Laboratory analysis revealed a culture of anaerobic

gram-positive spore-forming bacteria. What is the most likely kind of the isolated
causative agent?
+ C. perfringens
- Proteus vulgaris
- P. mirabilis
-Vibrio parahemolyticus
- Esherichia coli

?Gram-positive spore-forming bacilli were extracted in anoxic environment from the

patient�s wound contaminated with soil. Cultivation on a blood-glucose agar
resulted in growth of the colonies surrounded with hemolysis zone. What agent was
extracted from the wound?
+ Clostridium perfringens
- Clostridium botulinum
-Staphylococcus aureus
-Pseudomonas aeruginosa
- Esherichia coli

?On the 5th day after a surgery for colon injury a patient complains of bursting
pain in the postoperative wound, weakness, drowsiness, headache, fever up to 39-
Objectively: the skin around the wound is swollen, there is gas crepitation.The
wound discharges are scarce foul-smelling, of dark-gray color. What is the most
likely diagnosis?
+ Anaerobic clostridial wound infection
- Abscess
- Postoperative wound infection
-Erysipelas
- Phlegmon

?4 days after a patient received a gunshot wound of the middle third of the thigh
soft tissues his condition suddenly began deteriorating. There are complaints of
bursting pain in the wound; pain increases during the last 12 hours. Edema of skin
and hypodermic tissue quickly grows. Body temperature is 38,2oC, heart rate is
102/min. The wound edges gape, are dull in color; the muscles, viable as of day
before, now protrude into the wound, look boiled, are dull in color, have dirty-
grey coating and fall apart when being held with forceps. What infection has
developed in the wound?
+ Anaerobic
- Aerobic gram-negative
- Putrid
-Aerobic gram-positive
- Diphtheria of wound

?A laboratory received a material from a patient�s wound. Preliminary diagnosis is

gaseous gangrene. What microbiological method should be applied to determine
species of causative agent?
+ Bacteriological
- Allergic
- Bacterioscopic
-Serological
- RIA

?The following spore-forming bacteria can be preserved in soil over a long period
of time: clostridia of tetanus, botulism, anaerobic gas infection. Name the way
with which these microorganisms get into soil.
+ With feces
- With urine
- With water
-With industrial waters
- With expectoration

?A patient consulted a stomatologist about purulent inflammation of his gums. What

drug will be the most effective if it is suspected that a causative agent is an
anaerobe?
+Metronidazole
- Gentamicin
- Oxacillin
-Co-trimoxazole
- �

?For serological diagnostics of the whooping cough it was made large-scale reaction
with parapertussis and pertussis diagnosticums. At the bottom of the test-tubes
with diagnosticum of Bordetella parapertussis grain-like sediment formed. What
antibodies have this reaction revealed?
- Bacteriolysins
+ Agglutinins
- Antitoxins
- Opsonins
- Precipitins

?A large-scale reaction with parapertussis and pertussis diagnosticums was made in

order to make serological diagnostics of the whooping cough. At the bottom of the
test-tubes with diagnosticum of Bordetella parapertussis a granular sediment
formed. What antibodies did this reaction reveal?
+ Agglutinins
- Precipitins
- Opsonins
-Bacteriolysins
- Antitoxins

?A patient has been suffering from elevated temperature and attacks of typical
cough for 10 days. Doctor administered inoculation of mucus from the patient�s
nasopharynx on the agar. What microorganism is presumed?
+ Pertussis bacillus
- Pfeiffer�s bacillus
- Listeria
-Klebsiella
- Staphylococcus

?A patient has severe catarrhal symptoms. Material growth on Bordet-Gengou agar

showed mercury-drop like colonies. Examination of the blood smears revealed some
small ovoid gram-negative bacilli sized 1-3 microns. What microorganisms were
isolated?
+ Bordetella
- Corynebacteria
- Mycobacteria
-Meningococcus
- Brucella

?During bacteriological examination of sputum of a child with choking cough and

fever there were revealed glossy smooth colonies growing on casein-charcoal agar
and reminding of mercury drops. Microscopic examination revealed short Gram-
negative bacteria. What microorganism was secured from the sputum?
+ Bordetella pertussis
- Haemophylus influenzae
- Corynebacterium dyphtheriae
-neumoniaa neumonia
- Streptococcus pyogenes

?While studying a microslide obtained from the punctuate of a regional lymph node
and stained by Romanovsky-Giemsa method a physician revealed some light pink thin
microorganisms with 12-14 regular spiral coils and pointed ends, up to 10-13
micrometer long. This might be the causative agent of the following disease:
+Syphilis
-Trypanosomiasis
-Leptospirosis
-Relapsing fever
-Leishmaniasis

?In the micropreparation made from patient�s regional lymph node punctate and
stained according to Romanovsky-Giemsa method, the doctor found out thin
microorganisms with 12-14 equal ringlets and pale-pink sharp pointes 10-13 mkm in
length. The pathogen of what disease is it about?
-Leishmaniasis
- Leptospirosis
- Surra
+ Syphilis
- Relapsing fever

?In a microslide of the patient�s regional lymph node stained with Giemsa method a
doctor detected thin microorganisms with 12-14 uniform tendrils with pointed tips,
10-13 micrometers in length, pale pink in color. In this case they can be
identified as infectious agents of the following disease:
+ Syphilis
- Trypanosomiasis
- Leptospirosis
-Relapsing fever
- Leishmaniasis

?Bacterioscopic examination of chancre material revealed some mobile, long,

convoluted microorganisms with 8-12 regular coils. These features are typical for:
+ Treponema
- Borrellia
- Leptospira
-Vibrios
- Campylobacter

?An 18-year-old patient has enlarged inguinal lymph nodes, they are painless,
thickened on palpation. In the area of genital mucous membrane there is a small-
sized ulcer with thickened edges and �laquer�bottom of greyish colour. What is the
most probable diagnosis?
+ Syphilis
- Tuberculosis
- Lepra
-Trophic ulcer
- Gonorrhea

?A 14-year-old patient was diagnosed with Hutchinson�s triad: barrel-shaped

incisors, parenchymatous keratitis and deafness. The revealed presentations are
consistent with the following disease:
+ Syphilis
- Toxoplasmosis
- Lepra
-Tuberculosis
- �

?A dentist examined a 5-year-old boy and found him to have a saddle nose, high-
arched palate, natiform skull. Both front maxillary incisors are peg-shaped and
have a crescent-shaped notch in the cutting edge. Lymph nodes are not changed. What
is the provisional diagnosis?
+ Late congenital syphilis
- Early congenital syphilis
- Tertiary syphilis
-Fluorosis
- Rickettsiosis

?During examination of the patient�s oral cavity a dentist noticed deformation of

the teeth and a crescent indentation of the upper right incisor. The teeth are
undersized, barrel-shaped � tooth cervix is wider than its edge. The patient uses a
hearing aid, suffers from visual impairment. What type of syphilis affects teeth in
such way?
-Primary
- Early congenital
- Neurosyphilis
-Secondary
+ Late congenital

?A 32 y.o. man is divorced, has an irregular sexual life. He complains of falling

out of hair in the region of eyelashes, eyebrows, scalp. Objectively: diffuse
alopecia is observed, eyebrow margin is absent, eyelashes are stair-like (Pinkus�
sign). What examination should be carried out first of all?
+ Wasserman test, IFT
- T. pallidum Immobilization Test (TPI)
- Detection of the nasal mucous membrane for M. leprae
-Consultation of neuropathist
- CBC

?A patient who suffered form syphilis took a course of antibiotic therapy and fully
recovered. Some time later he was infected again with Treponema pallidum. What form
of infection is it?
+ Reinfection
- Recurrence
- Superinfection
-Relapse
- Complication

?
A patient had been provisionally diagnosed with syphilis. A laboratory assistant
took the blood serum for an immunologic test based on the detection of antibodies
preventing the movement of treponemas and causing their death. What reaction was
used for the diagnosis?
+ Immobilization
- Complement binding
- Agglutination
-Precipitation
- Neutralization

?A 32-year-old patient undergoing dental examination was found to have some rash-
like lesions resembling secondary syphilis in the oral cavity. The patient was
referred for the serological study with the purpose of diagnosis confirmation. In
order to detect antibodies in the serum, living Treponema were used as
diagnosticum. What serological test was performed?
+ Immobilization
- Passive HA
- PT
-CFT
- Nt

?A patient suffering from syphilis was prescribed a drug the action of which based
upon disturbed generation of murein leading to death of the causative agent. What
drug is it?
+ Benzylpenicillin sodium salt
- Bijochinol
- Ciprofloxacin
-Azithromycin
- Doxycycline

?
A 19 year old woman suffers from primary syphilis. Doctor administered her complex
therapy that includes benzylpenicillin sodium salt. What is the mechanism of action
of this drug?
+ It blocks synthesis of peptidoglycan of microbial membrane
- It blocks synthesis of cytoplasm proteins
- It blocks thiol enzymes
-It blocks RNA synthesis
- It blocks DNA synthesis

?A man was admitted to the hospital on the 5th day of disease that manifested
itself by jaundice, muscle aching, chill, nose bleedings. In course of laboratory
diagnostics a bacteriologist performed darkfield microscopy of the patient�s blood
drop. Name a causative agent of this disease:
+ Leptospira interrogans
- Borrelia dutlonii
-Calymmatobacterium granulomatis
-Bartonella bacilloformis
-Rickettsia mooseri

?A patient was admitted to the hospital on the 7th day of the disease with
complaints of high temperature, headache, pain in the muscles, especially in calf
muscles. Dermal integuments and scleras are icteric. There is hemorrhagic rash on
the skin. Urine is bloody. The patient was fishing two weeks ago. What is the most
likely diagnosis?
+ Leptospirosis
- Yersiniosis
- Salmonellosis
-Brucellosis
- Trichinellosis

?
A 33 year old patient was delivered to the infectious diseases department on the 7-
th day of disease. He complained about great weakness, high temperature, pain in
the lumbar area and leg muscles, icteritiousness, dark color of urine, headache.
The acute disease started with chill, body temperature rise up to 40C, headache,
pain in the lumbar area and sural muscles. Icterus turned up on the 4th day, nasal
and scleral haemorrhages came on the 5th day. Fever has lasted for 6 days. Diuresis
� 200 ml. What is the most probable diagnosis?
+ Leptospirosis
- Typhoid fever
- Virus A hepatitis
-Sepsis
- Yersiniosis

?A 25-year-old patient was delivered to an infectious diseases unit on the 3rd day
of illness with complaints of headache, pain in lumbar spine and gastrocnemius
muscles, high fever, chill. Objectively: condition of moderate severity. Scleras
are icteric. Pharynx is hyperemic. Tongue is dry with dry brown coating. Abdomen is
distended. Liver is enlarged by 2 cm. Spleen is not enlarged. Palpation of muscles,
especially gastrocnemius muscles, is painful. Urine is dark in color. Stool is
normal in color. The most likely diagnosis is:
+ Leptospirosis
- Infectious mononucleosis
- Viral hepatitis A
-Malaria
- Yersiniosis

?A man died from an acute infectious disease accompanied by fever, jaundice,

haemorrhagic rash on the skin and mucous membranes as well as by acute renal
insufficiency. Histological examination of renal tissue (stained by Romanovsky-
Giemsa method) revealed some convoluted bacteria looking like C and S letters. What
bacteria were revealed?
+ Leptospira
- Treponema
- Spirilla
-Borrelia
- Campilobacteria

?Etiological factors for the infectious diseases are often microorganisms with
various ultrastructure. Which of the following microorganism groups relates to the
eukaryotes?
+Protozoa
-Viruses
-Viroids
-Prions
-Scotobacteria

?In order to prevent wound infection associated with surgical procedures a patient
was given a synthetic antiprotozoan drug with a high activity against Helicobacter
pylori. Specify this drug:
+ Metronidazole
- Doxycycline hydrochloride
- Chingamin
-Acyclovir
- Isoniazid

?A dentist has detected symptoms of parodontosis in a patient. What antiprotozoal

drug should be prescribed?
+ Metronidazole
- Levamisole
- Griseofulvin
-Mykoseptin
- Furazolidone

?
Patients with similar complaints applied to the doctor: weakness, pain in the
intestines, disorder of GIT. Examination of the feces revealed that one patient
with four nucleus cysts should be hospitalized immediately. For what protozoa are
such cysts typical?
-Lamblia
+Dysenteric amoeba
- Balantidium
-Trichomonas
- Intestinal amoeba

?Several patients with similar complaints came to the doctor. They all present with
weakness, pain in the intestines, indigestion. Feces analysis revealed the need for
urgent hospitalization of the patient, who had microbial cysts with four nuclei
detected in his samples. Such cysts are characteristic of the following protozoon:
+ Entamoeba histolytica.
- Entamoeba coli.
- Balantidium.
-Trichomonad.
- Lamblia.

?A patient complains of frequent bowel movements and stool with blood admixtures
("raspberry jelly" stool). Microscopic examination revealed large mononuclear cells
with absorbed red blood cells. What protozoon is this morphological structure
typical for?
+ Entamoeba histolytica
- Giardia lamblia
- Campylobacter jejuni
-Toxoplasma gondii
- Balantidium coli

?A 40-year-old patient presents with abdominal pain, frequent loose stools with
mucus and blood. Stool analysis revealed vegetative forms of some protozoa sized
30-40 microns, with short pseudopodia, containing large amounts of phagocytosed
erythrocytes. What protozoan disease does the patient have?
+ Amebiasis
- Leishmaniasis
- Trichomoniasis
-Giardiasis
- Toxoplasmosis

?A patient complains of acute spastic abdominal pain, frequent urge to defecate,

liquid bloody feces with mucus. Laboratory analysis of fecal smear revealed
inconstant in shape organisms with erythrocyte. What is the most likely diagnosis?
+ Amebiasis.
- Lambliasis.
- Schistosomiasis.
-Intestinal trichomoniasis.
- Balantidiasis.

?A patient with suspected liver abscess was admitted to the surgical department.The
patient had been staying for a long time on business in one of African countries
and fell repeatedly ill with acute gastrointestinal disorders. What protozoal
disease may the patient be now ill with?
+ Amebiasis
- Trypanosomosis
- Leishmaniasis
-Malaria
- Toxoplasmosis

?Among public catering workers examined by doctors of sanitary and epidemiologic

station often occur asymptomatic parasite carriers. This means that a healthy
person carries cysts that infect other people. Such parasitizing is possible for
the following causative agent:
+ Dysenteric amoeba
- Malarial plasmodium
- Intestinal trichomonad
-Dermatotropic leishmania
- Viscerotropic leishmania

?When doctors of a sanitary and epidemiologic institution examine employees of

public catering establishments they often reveal asymptomatic parasitosis, that is
when a healthy person is a carrier of cysts that infect other people. What
causative agent can parasitize in such a way?
+ Dysenteric amoeba
- Malarial plasmodium
- Enteral trichomonad
-Dermatotropic leishmania
- Viscerotropic leishmania

?Microscopy of dental plaque revealed unicellular organisms. Their cytoplasm had

two distinct layers, barely visible core, wide pseudopodia. The patient is most
likely to have:
+ Entamoeba gingivalis
- Entamoeba histolytica
- Trichomonas tenax
-Lamblia
- Entamoeba coli

?Carious cavities of a 29-year-old patient contain the parasitic protozoa. It is

established that they relate to the Sarcodina class. Specify these single-celled
organisms:
+ Entamoeba gingivalis
- Entamoeba histolutica
- Entamoeba coli
-Amoeba proteus
- Lamblia intestinalis

?A 52-year-old patient has the following diagnosis: systemic amebiasis with

involvment of intestines, liver, lungs. What drug should be prescribed?
+ Metronidazole
- Quiniofone
- Tetracycline
-Quingamine
- Enteroseptol

?Systemic amebiasis with involvment of intestines, liver, lungs was diagnosed in a

52-year-old patient. What drug should be prescribed?
-Quiniofone
- Enteroseptol
+ Metronidazole
-Tetracycline
- Quingamine

?What drug is more advisable for the patient with amebic dysentery?
+ Metronidazole
- Pyrantel
- Levamisole
-Bicillin-5
- Benzylpenicillin sodium salt (Penicillin G sodium salt)

?A 30-year-old patient complains about having abdominal pain and diarrhea for five
days; body temperature rise up to 37, 5oC along with chills. The day before a
patient had been in a forest and drunk from an open water reservoir. Laboratory
analyses enabled to make the following diagnosis: amebic dysentery. What is the
drug of choice for its treatment?
+ Metronidazole
- Furazolidonum
- Levomycetin
-Phthalazol
- Emetine hydrochloride

?A 30 year old patient consulted a doctor about having diarrhea and stomach aches
for 5 days, temperature rise up to 37,50C with chills. The day before the patient
was in a forest and drank some water from an open pond. He was diagnosed with
amebic dysentery that was bacteriologically confirmed. Name the medication for
treatment of this disease:
+ Metronidazole
- Furasolidone
- Chloramphenicol
-Phthalazole
- Emethine hydrochloride

?A 30 y.o. patient is diagnosed with amebic dysentery. This diagnosis was

bacteriologically confirmed. Name the preparation for its treatment:
+ Metronidazole
- Mebendazole
- Itrakonazole
-Furacillin
- Acyclovir

?A patient ill with amebiasis was prescribed a certain drug. The use of alcohol
together with this drug is contraindicated because the drug inhibits metabolism of
ethyl alcohol. What drug is it?
+ Metronidazole
- Reserpine
- Clonidine
-Diazepam
- Aminazine

?Examination of duodenal contents revealed some pyriform protozoa with twin nuclei
and four pairs of flagella. There were two supporting filaments between the nuclei
and a suctorial disc on the ventral side. What representative of protozoa was
revealed in this patient?
+ Lamblia
- Toxoplasma
- Leishmania
-Intestinal trichomonad
- Trypanosome

?Examination of the duodenal contents revealed some pear-shaped protozoa with two
nuclei and four pairs of flagella. The organisms had also two axostyles between the
nuclei and a ventral adhesive disc. What protozoan representative was found in the
patient?
+ Lamblia
- Toxoplasma
- Leishmania
-Intestinal trichomonad
- Trypanosome

?A duodenal content smear of a patient with indigestion contains protozoa 10- mcm
large. They have piriform bodies, 4 pairs of filaments, two symmetrically located
nuclei in the broadened part of body. What kind of the lowest organisms is it?
+ Lamblia
- Dysentery ameba
- Trichomonas
-Intestinal ameba
- Balantidium

?A 13 year old child complains about poor appetite, pain in the right subcostal
area. Microscopical examination of duodenal contents revealed big pyriform cells
with two nuclei. What microorganism was revealed?
+ Lamblia
- Trichomonas
- Amoeba
-Trypanosoma
- Toxoplasma

?A female patient consulted a doctor about a sense of epigastric discomfort, nausea

and anorexia. A duodenal content analysis revealed lamblia. What drug should be
prescribed?
+Metronidazole
-Chingamin
-Rifampicin
-Isoniazid
-Acyclovir

?
A patient consulted a doctor about bowels disfunction. The doctor established
symptoms of duodenitis and enteritis. Laboratory examination helped to make the
following diagnosis: lambliosis. What medication should be administered?
+ Metronidazole
- Erythromycin
- Monomycin
-Chingamin
- Tetracycline

?Sanitary assessment of a pond, where the children from a recreation summer camp
take their swims, detected there oval cysts 50-60 micron in diameter, with 2 nuclei
visible in their cytoplasm (macronucleus and micronucleus). What protozoa do these
cysts belong to?
-Toxoplasma
- Amoeba
+ Balantidium
-Lamblia
- Euglena

?A patient working at a pig farm complains about paroxysmal abdominal pain, liquid
feces with admixtures of mucus and blood, headache, weakness, fever. Examination of
large intestine revealed ulcers from 1 mm up to several cm large, feces contained
oval unicellular organisms with cilia. What disease should be suspected?
+ Balantidiasis
- Amebiasis
- Toxoplasmosis
-Lambliasis
- Trichomoniasis

?
Slime, blood and protozoa 30-200 microns of length have been revealed in a man�s
feces. The body is covered with cilias and has correct oval form with a little bit
narrowed forward and wide round shaped back end. On the forward end a mouth is
visible. In cytoplasm there are two nucleuses and two short vacuoles. For whom are
the described attributes typical?
+ Balantidium
- Lamblia
- Dysenteric amoeba
-Trichomonas
- Intestinal amoeba

?Parents with ill child came to the infectionist. They worked in one of the Asian
countries for a long time. Child has eathy colored skin, loss of appetite, laxity,
enlarged liver, spleen, peripheral glands. What protozoan illness can this child
have?
-Amebiasis
- Balantidiasis
+ Visceral leishmaniasis
-Lambliasis
- Toxoplasmosis

?A patient has roundish ulcers on his face, inflammation and enlargement of lymph
nodes. These symptoms turned up as a result of mosquito bites. Laboratory
examination of discharge from the ulcers revealed unicellular aflagellar organisms.
What is the most probable diagnosis?
+ Dermatotropic leishmaniasis
- Toxoplasmosis
- Scabies
-Trypanosomiasis
- Myasis

?A group of Ukrainian tourists returning from Samarqand was bringing with them
gerbils. During examination in customs office ulcers were detected on the skin of
the animals. What protozoa is the most likely to cause the disease in the animals,
if mosquitoes are the carriers?
+ Leishmania tropica major
- Balantidium coli
- P. falciparum
-T. cruzi
- Toxoplasma gondii

?While examining a blood smear taken form a patient and stained by

Romanovsky�s method a doctor revealed some protozoa and diagnozed the patient with
Chagas disease. What protozoan is the causative agent of this disease?
+ Trypanosoma cruzi
- Toxoplasma gondii
- Leishmania donovani
-Leishmania tropica
- Trypanosoma brucei

?In the South and Central America there can be found a species of trypanosomes that
is the causative agent of Chagas disease. What animal is the infection carrier
specific to this disease?
-Gnat
- Mosquito
- Tsetse fly
-Cockroach
+ Triatomine bug

?A businessman came to India from South America. On examination the physician found
that the patient was suffering from sleeping-sickness. What was the way of
invasion?
+ As a result of bug�s bites
- As a result of mosquito�s bites
- With contaminated fruits and vegetables
-Through dirty hands
- After contact with a sick dogs

?A patient has symptoms of inflammation of urogenital tracts. Examination of a

vaginal smear revealed big monocellular, pear-shaped organisms with the pointed
spike at the posterior end of body, big nucleus and undulating membrane. What
protozoa were found in the smear?
+ Trichomonas vaginalis
- Trichomonas hominis
- Trichomonas buccalis
-Trypanosoma gambiense
- Lamblia intestinalis

?A gynaecologist was examining a patient and revealed symptoms of genital tract

inflammation. A smear from vagina contains pyriform protozoa with a spine, flagella
at their front; there is also an undulating membrane. What disease can be
suspected?
+ Urogenital trichomoniasis
- Lambliasis
- Intestinal trichomoniasis
-Toxoplasmosis
- Balantidiasis

?A female patient has symptoms of inflammation of urogenital tracts. A smear from

the vaginal mucous membrane contained big unicellular pyriform organisms with a
sharp spike on the back end of their bodies; big nucleus and undulating membrane.
What protozoa were revealed in the smear?
+ Trichomonas vaginalis
- Trichomonas hominis
- Trichomonas buccalis
-Trypanosoma gambiense
- Lamblia intestinalis

?Microscopical examination of discharges from the gums of a patient ill with

paradontosis revealed some protozoan pear-shaped organisms 6-13 micrometer long.
The parasite has one nucleus and undulating membrane, there are four flagella at
the front of its body. What protozoan were found?
+ Trichomonads
- Leishmania
- Amoebae
-Balantidia
- Lamblia

?A smear from frothy and purulent vaginal discharges of a 42 y.o. woman was stained
by Romanovsky-Giemsa method. Its analysis revealed some microorganisms of
flagellates class. What microorganism were the most probably revealed?
+ Trichomonas vaginalis
- Leishmania donovani
- Trypanosoma gambiense
-Trihomonas hominis
- Lamblia intestinalis

?A 42-year-old female has foamy purulent vaginal discharges. The smear stained by
Romanovsky-Giemsa�s method has been found to include flagellated bacteria. What is
the most likely microorganism that has been found by the doctor?
+ Trichomonas vaginalis
- Trypanosoma gambiense
- Leishmania donovani
-Trihomonas hominis
- Lamblia intestinalis

?A patient consulted a dentist about itching and burning in the oral cavity; high
temperature. The patient was diagnosed with trichomonal gingivostomatitis. What
drug should be chosen for his treatment?
+ Metronidazole
- Ampicillin
- Gentamicin sulfate
-Nystatin
- Doxycycline hydrochloride

?As an example of specific human parasites one can name Plasmodium falciparum,
human pinworm and some others. The source of parasite invasion is always a human.
Such specific human parasites cause the diseases that are called:
+ Anthroponoses
- Zoonoses
- Anthropozoonoses
-Infections
- Multifactorial Diseases

?A patient who has recently come from an endemic area presents with elevated body
temperature, headache, chills, malaise, that is with the symptoms which are typical
for a common cold. What laboratory tests are necessary to confirm or to refute the
diagnosis of malaria?
+ Microscopy of blood Smears
- Study of lymph node punctate
- Urinalysis
-Study of cerebrospinal fluid
- Microscopy of bone marrow punctuate

?According to the data of WHO, for about 250 mln of Earth population fall ill with
malaria. This disease is mostly spread in tropical and subtropical regions. Range
of its spread falls into the area of the following mosquitoes:
+ Anopheles
- Culex
- Aedes
-Mansonia
- Culiseta

?A patient has been brought to the hospital with the complaints of headache, pain
in left hypochondrium. He has been ill for 1,5 weeks. The sudden illness began with
the increase of body temperature up to 39, 90- In 3 hours the temperature decreased
and hydropoiesis began. The attacks repeat rhythmically in hours. The patient had
visited one an African country. The doctors have suspected malaria. What method of
laboratory diagnostics is necessary to use?
+ Blood examination
- Immunological tests
- Stool examination
-Urine examination
- �

?A journalist�s body temperature has sharply increased in the morning three weeks
after his mission in India, it was accompanied with shivering and bad headache. A
few hours later the temperature decreased. The attacks began to repeat in a day. He
was diagnosed with tropical malaria. What stage of development of Plasmodium is
infective for anopheles-female?
+ Gametocytes
- Shizontes
- Merozoites
-Microgamete
- Sporozoites

?A 47-year-old patient came to see a doctor on the 7th day of disease. The disease
developed very fast: after the chill body temperature rose to 40oC and lasted up to
7 hours, then dropped abruptly, which caused profuse sweat. There were three such
attacks occur in once in two days. Two days ago the patient arrived from Africa.
Objectively: pale skin, subicteric sclera, significantly enlarged liver and spleen.
What is the cause of fever attacks in this disease?
+ Erythrocytic schizogony
- Tissue schizogony
- Gametocytes
-Exotoxin of a causative agent
- Endotoxin of a causative agent

?A 34-year-old male visited Tajikistan. After return, he complains of fever up to

40oC which occurs every second day and is accompanied by chills, sweating.
Hepatosplenomegaly is present. Blood test results: RBC- 3x1012/l, �b- 80 g/l, WBC-
4x109/l, eosinophils - 1%, stab neutrophils - 5%, segmented neutrophils - 60%,
lymphocytes - 24%, monocytes - 10%, ESR - 25 mm/h. What is the provisional
diagnosis?
+ Malaria
- Infectious mononucleosis
- Sepsis
-Typhoid fever
- Leptospirosis

?A 23 year old female patient complains about periodical chill and body temperature
rise up to 40oC, sense of heat taking turns with profuse sweating. The patient has
had already 3 attacks that came once in two days and lasted 12 hours. She has lived
in Africa for the last 2 months. Liver and spleen are enlarged. In blood:
erythrocytes - 2,5x1012/l. What is the most probable diagnosis?
+ Malaria
- Spotted fever
- Sepsis
-Hemolytic anaemia
- Leptospirosis

?2 weeks since the blood transfusion a recepient has developed fever. What
protozoal disease can it be?
+ Malaria
- Trypanosomiasis
- Amebiasis
-Toxoplasmosis
- Leishmaniasis

?Two weeks after hemotransfusion a patient developed fever. What protozoal disease
can be suspected?
+ Malaria
- Toxoplasmosis
- Leishmaniasis
-Amebiasis
- Trypanosomiasis

?A healthy man is in a region with high risk of catching malaria. What drug should
be administered for individual chemoprophylaxis of malaria?
+Chingamin
-Sulfalen
-Tetracycline
-Metronidazole
-Biseptol

?This drug has a destructive effect on erythrocytic forms of malarial plasmodia and
dysenteric amoebae. It is used for treatment and prevention of such diseases as
malaria, amebiasis and interstitial disease. What drug is it?
+ Chingamin
- Emetine hydrochloride
- Tetracycline
-Erythromycin
- Quinine

?What drug should be administered for individual prevention of malaria?

+ Chingamin
- Rifampicin
- Ampicillin
-Gentamicin
- Biseptol (Co-Trimoxazolel)

?UN volunteers have arrived in Nigeria to assist the locals in aftermath of

earthquakes. What drug should they prescribe for individual chemoprophylaxis of
malaria?
+ Chingamin
- Pyrimethamine (Chloridinum)
- Interferon
-Primaquine
- Pyrantel

?In preparation for business trip abroad the doctor was prescribed a
histoschizontocidal antimalarial drug as a personal means of disease prevention.
What drug was given to the doctor?
+ Chingamin
- Biseptol (Co- Trimoxazole)
- Mefloquine
-Quinine
- Doxycycline

?A lymph node punctate of a patient with suspected protozoa disease was examined.
Examination of the stained specimen (Romanovsky�s stain) revealed some crescent
bodies with pointed end, blue cytoplasm and red nucleus. What protozoan were
revealed in the smears?
+ Toxoplasmas
- Malarial plasmodiums
- Dermotropic leishmania
-Viscerotropic leishmania
- Trypanosomes

?A puncture sample taken from the lymph node of a patient with preliminary
diagnosis of protozoan disease has been investigated. The preparation was processed
with Giemsa stain and the following was detected: crescent-shaped bodies with
pointed tips, blue cytoplasm and red nuclei. What protozoa have been detected in
the preparation?
+ Toxoplasma
- Plasmodium malariae
- Trypanosoma
-Viscerotropic Leishmania
- Dermatotropic Leishmania
?Examination of a man revealed a protozoan disease that affected brain and caused
vision loss. Blood analysis revealed unicellular half-moon-shaped organisms with
pointed end. The causative agent of this disease is:
+ Toxoplasma
- Leishmania
- Lamblia
-Amoeba
- Trichmonad

?A man is ill with a protozoan disease characterized by cerebral affection and loss
of sight. Blood analysis revealed halfmoon-shaped unicellular organisms with
pointed ends. This disease is caused by:
+ Toxoplasma
- Leishmania
- Lamblia
-Amoeba
- Trichomonad

?A woman who was infected with toxoplasmosis during the pregnancy has a child with
multiple congenital defects. This is a result of:
+ Teratogenesis
- Cancerogenesis
- Recombination
-Chemical mutogenesis
- Biological mutogenesis

?A woman delivered a dead child with multiple developmental defects. What protozoan
disease might have caused the intrauterine death?
+ Toxoplasmosis
- Leishmaniasis
- Malaria
-Amebiasis
- Lambliasis

?A woman gave birth to a stillborn baby with numerous malformations. What protozoan
disease could cause intrauterine death?
+ Toxoplasmosis
- Leishmaniasis
- Malaria
-Amebiasis
- Lambliasis

?A married couple applied to the genetic consultation in order to consult about

their child with multiple abnormalities (microcephaly, idiocy etc). The woman has
had an illnesses during her pregnancy but she didn�t take any teratogens or
mutagens. The parents� and the child�s karyotype is normal. Anamnesis study
revealed that the family kept a cat. What gravidic disease caused the child�s
abnormalities?
+ Toxoplasmosis
- Leishmaniasis
- Dysentery
-Balantidiasis
- Trichomoniasis

?A patient�s preliminary diagnosis is toxoplasmosis. What material was used for

diagnostics of this disease?
+ Blood
- Feces
- Urine
-Duodenal contents
- Sputum

?A patient who came to the doctor because of his infertility was administered to
make tests for toxoplasmosis and chronic gonorrhoea. Which reaction should be
performed to reveal latent toxoplasmosis and chronic gonorrhoea in this patient?
-RIHA - Reverse indirect hemagglutination assay
- RDHA - Reverse direct hemagglutination assay
- IFA - Immunofluorescence assay
-Immunoblot analysis
+ (R)CFT- Reiter's complement fixation test

?A pregnant woman applied to a doctor with complaints typical for toxoplasmosis.

The doctor took a sample of her blood. What serological tests should be performed
in this case?
+ Complement binding assay
- Precipitation test
- Neutralization test
-Widal�s test
- Wassermann test

?After the second abortion a 23 year old woman has been diagnosed with
toxoplasmosis. Which drug should be used for toxoplasmosis treatment?
+ Co-trimoxazole
- Itraconazole
- Mebendazole
-Azidothimidine
- Acyclovir

?A patient with suspicion on epidemic typhus was admitted to the hospital. Some
arachnids and insects have been found in his flat. Which of them may be a carrier
of the pathogen of epidemic typhus?
+ Lice
- Spiders
- Bed-bugs
-Cockroaches
- Houseflies

?A sick man with high temperature and a lot of tiny wounds on the body has been
admitted to the hospital. Lice have been found in the folds of his clothing. What
disease can be suspected in the patient?
+ Epidemic typhus
- Tularemia
- Scabies
-Malaria
- Plague

?A 28 y.o. homeless male was admitted to the hospital because of initial diagnosis
"influenza". Roseolo-petechiae rash has appeared on the trunk and internal surfaces
of the limbs on the fifth day. Temperature is 410C, euphoria, face and sclera�s
hyperemia, tongue tremor, tachycardia, splenomegaly, excitement. What is the most
probable diagnosis?
+ Typhus
- Alcogolic delirium
- Leptospirosis
-Abdominal typhoid
- Measles

?A 28 y.o. patient without permanent residence was admitted to the hospital with
the preliminary diagnosis influenza. On the fith day of illness he got a
maculopapular petechial rash on his body and internal surfaces of extremities. Body
temperature is 410 C, euphoria, face hyperemia, sclera reddening, tongue tremor,
tachycardia, splenomegaly, excitement. What is the most probable diagnosis?
+ Epidemic typhus
- Delirium alcoholicum
- Leptospirosis
-Measles
- Typhoid fever

?A 28-year-old patient was hospitalized with preliminary diagnosis "influenza".

Roseolous-petechial rash appeared on the 5th day of disease on the trunk. The
temperature is 41o- Hyperemia of face, reddening of scleras, tremor of tongue,
tachycardia, splenomegaly are present. What is the most likely diagnosis?
+ Epidemic typhus
- Measles
- Alcohol delirium
-Leptospirosis
- Typhoid fever

?A 55-year-old patient with a characteristic rash, fever, dizziness has been

admitted to a hospital. He has been provisionally diagnosed with typhus. No similar
cases have been reported. In his youth (15 years old) the patient suffered typhus
in a boarding school. What disease is it?
+ Brill�s disease
- Typhoid fever
- Measles
-Rubella
- Cholera

?5 days before, a 26-year-old female patient developed an acute condition.

Objectively: marked headache, vomiting, weakness, poor appetite, temperature up to
39o- Objectively: the patient is in a moderately grave condition, excited. The face
is hyperemic, sclerae are injected. The tongue is coated with brown fur. The trunk
and limbs are covered with plentiful roseolous and petechial rash.
Hepatosplenomegaly is present. Complement binding reaction with Rickettsia
prowazekii is positive with the titer of 1:640. What drug should be administered?
+ Doxycycline
- Chloramphenicol
- Penicillin
-Streptomycin
- Metronidazole

?A 35-year-old patient has been admitted to a hospital for pain in the left
sternoclavicular and knee joints, lumbar area. The disease has an acute character
and is accompanied by fever up to 38o- Objectively: the left sternoclavicular and
knee joints are swollen and painful. In blood: WBCs - 9, 5x109/l, ESR - 40 mm/h,
CRP - 1,5 millimole/l, fibrinogen - 4,8 g/l, uric acid - 0,28 millimole/l.
Examination of the urethra scrapings reveals chlamydia. What is the most likely
diagnosis?
+ Reiter�s syndrome
- Rheumatic arthritis
- Gout
-Bechterew�s disease
- Rheumatoid arthritis

?On the base of the clinical data a child was diagnosed with atypical pneumonia
resistant to the effects of beta-lactam antibiotics. The patient�s sputum was
cultured and incubated in a special medium, which resulted in growth of
microorganisms forming microscopic colonies with a dense center (looking like fried
eggs). What microorganism caused the disease?
+ Mycoplasma pneumoniae
- Klebsiella pneumoniae
- Str. pneumoniae
-L. pneumophila
- Chlamidia pneumonia

?From a medicinal herb a certain phytopathogenic microorganism was secured. In the

nutrient medium it forms "fried egg"colonies. What is the most likely agent?
+ Mycoplasma
- Yeasts
- Actinomycetes
-Nocardia
- Pseudoonas

?A 22-year-old patient is a clerk. His working day runs in a conditioned room. In

summer he was taken by an acute disease with the following symptoms: fever,
dyspnea, dry cough, pleural pain, myalgia, arthralgia. Objectively: moist rales on
the right, pleural friction rub. X-ray picture showed infiltration of the inferior
lobe. In blood: WBC - 11 � 109/l, stab neutrophils - 6%, segmented neutrophils -
70%, lymphocytes - 8%, ESR - 42 mm/h. What is the etiological factor pneumonia?
+ Legionella
- Mycoplasma
- Streptococcus
-Staphylococcus
- Pneumococcus

?A 21-year-old female patient consulted a gynecologist about itching, burning,

watery vaginal discharges with a fish-like smell. Speculum examination revealed
that the cervical and vaginal mucosa was of a normal pink color. Vaginal
examination revealed no alterations of the uterus and appendages. Gram-stained
smears included clue cells. What is the most likely pathology?
+ Bacterial vaginosis (gardnerellosis)
- Chlamydiosis
- Gonorrhea
-Trichomoniasis
- Candidiasis

?Bacteriological examination of the urine of the patient with pyelonephritis

revealed microorganisms that produced yellow-green pigment and a characteristic
odor in meat-peptone agar. What are they called?
+ Pseudomonas
- Escherichia
- Proteus
-Klebsiella
- Azotobacter

?Many diseases of medicinal plants are caused by bacteria of the Pseudomonas genus.
Select the bacteria relating to this genus:
+ Blue pus bacillus
- Colon bacillus
- Proteus
-Mycoplasma
- Micrococci

?Urine examination of a patient with acute cystitis revealed leukocytes and a lot
of gram-negative bacilli. Inoculation resulted in growth of colonies of mucous
nature that formed green soluble pigment. What microorganism is the most probable
cause of the disease?
+ Pseudomonas aeruginosa
- Klebsiella pneumoniae
- Escherihia coli
-Proteus mirabilis
- Salmonella enteritidis

?A patient of surgical department complains about pain in the small of her back and
in the lower part of her belly; painful and frequent urination. Bacteriological
examination of urine revealed gram-negative oxidase-positive rod-like bacteria
forming greenish mucoid colonies with specific smell. What causative agent can it
be?
+ Pseudomonas aeruginosa
- Mycoplasma pneumonie
- Str.pyogenes
-E coli
- Proteus mirabilis

?A patient has wound abscess. Bacteriological examination of the wound content

revealed a gram-negative bacillus which forms semi-transparent mucous colonies of
blue-green color with a pearlescent appearance on the beef-extract agar. Culture
has a specific odor of violets or jasmine. What type of pathogen was isolated from
the patient�s wound?
+ P. aeruginosa
- P.vulgaris
- S.aureus
-S.pyogenes
- S.faecalis

?A patient of oral surgery department has developed a purulent complication.

Bacteriological analysis of the wound discharge allowed to isolate a culture
producing a blue-and-green pigment. Which of the listed microorganisms may be a
causative agent of the infection?
+ Pseudomonas aeruginosa
- Staph. epidermidis
- B.subtilis
-Pr. vulgaris
- Klebsiella pneumoniae

?A patient in the oral surgery department has got purulent complication.

Bacteriological analysis of the wound material found a culture that produces cyan
pigment. What microorganism is the most probable causative agent?
+ Pseudomonas aeruginosa
- Staph. epidermidis
- B. subtilis
-Kleb. pneumoniae
- Pr.vulgaris

?A patient being treated in the burns department has suppurative complication. The
pus is of bluish-green color that is indicative of infection caused by Pseudomonas
aeruginosa. What factor is typical for this causative agent?
+ Gram-negative stain
- Presense of spores
- Coccal form
-Cell pairing
- Mycelium formation

?Bacteriological inspection of disinfection quality at a pharmacy revealed a

microorganism in an utility room (in the sink). The microorganism has the following
properties: mobile nonspore-forming gram-negative bacteria that form capsular
substance, grow well on ordinary nutrient media, secrete the blue-green pigment.
This microorganism is most likely to be of the following genus:
+ Pseudomonas
- Proteus
- Clostridium
-Shigella
- Vibrio

?A sample of a finished dosage form was found to be contaminated with some

microorganisms exhibiting the following properties: greenish fluorescent colonies
of gram-negative nonsporeforming bacilli that grew on the medium for the detection
of pyocyanin. The bacilli release the bluegreen pigment into the medium. What
microorganisms contaminated the finished dosage form?
+ Pseudomonas aeruginosa
- Enterobacteriaceae
- Staphylococcus aureus
-Staphylococcus epidermidis
- Staph. saprophyticus

?During bacteriological examination of the purulent discharge obtained from a

postoperative wound an inoculation on meat infusion agar has been performed. The
inoculation has resulted in large colorless mucous colonies that in 24 hours with
exposure to sunlight developed green-blue pigmentation and smell of honey or
jasmine. Bacterioscopy revealed gram-negative lophotrichea. What bacterial culture
is contained in purulent discharge?
+ Pseudomonas aeruginosa
- Klebsiella osaenae
- Streptomyces griseus
-Proteus vulgaris
- Brucella abortus

?A 60-year-old patient was hospitalized to the surgical department because of

infection caused by blue pus bacillus (Pseudomonas aeruginosa) which is sensative
to penicillin antibiotics. Indicate which of the given penicillins has marked
activity to the Pseudomonas aeruginosa?
+ Carbenicillin disodium
- Benzylpenicillin
- Methicillin
-Oxacillin
- Methylpenicillin

?A patient suffers from severe postoperative pseudomonadous infection. What of the

following antibiotics should be administered in this case?
+ Amicacin sulfate
- Benzylpenicillin
- Cephazolin
-Erythromycin
- Doxycycline

?From urine of a 14-year-old boy with the exacerbation of secondary obstructive

pyelonephritis Pseudomonas aeruginosa was isolated with a titer of 1000000 microbes
per 1 ml. Which antibiotic is most advisable to be administered in this case?
+ Ciprofloxacin
- Ampicillin
- Cefazolinum
-Azithromycin
- Chloramphenicol
?Impression smear of mucosa biopsy material has been obtained from a patient with
peptic ulcer disease of the stomach. Gram-negative arcuate bent microorganisms were
detected, urease activity test was positive. What microorganisms were detected in
the patient?
+ Helicobacter
- Spirochete
- Spirilla
-Leptospira
- Treponema

?A male patient has been diagnosed with gastric ulcer. Bacteriological examination
of biopsy material from the affected part of stomach revealed small colonies of
gram-negative, oxide reductase-positive flexibacteria that grew on the chocolate
agar on the fifth day. Which of the following microorganisms is the most likely
causative agent?
+ Helicobacter pylori
- Campilobacter jejuni
- Campilobacter fetus
-Mycoplasma hominis
- Chlamydia trachomatis

?A patient underwent esophagogastroduodenoscopy. Analysis of the biopsy material

enabled doctors to diagnose him with helicobacteriosis. What property of the
bacteria found in this patient had to be obligatory taken into account during their
cultivation?
+ Microaerophilic ability
- Presence of urease
- Absence of spores and capsules
-Colonisation of gastral cells
- Presence of six polar flagella

?During fibergastroscopy a patient with ulcer disease of the stomach, the mucosal
biopsy is taken from the area of an ulcer. Impression smear is prepared from biopsy
material and stained by Gram method; the rest of biopsy material is tested for
urease activity. Microscopy of the impression smear revealed gram-negative spiral-
shaped microorganisms, urease activity test is positive. What bacteria were
detected?
+ Helicobacter pylori
- Campilobacter jejuni
- Treponema pallidum
-Spirilla minor
- Shigella flexneri

?A 42-year-old patient with gastric ulcer has a disbalance between the aggressive
and defensive factors. Which of the following factors contributes to the
development of gastric ulcer?
+ Helicobacter pylori
- Mucin
- Hydrocarbonate
-Prostaglandin
- Prostacyclin

?A 32 year old patient complains about heartburn and dull pain in the epigastrium
that appear 2-3 hours after meal. Exacerbations happen in spring and in autumn. The
patient has food intolerance of eggs and fish. Objectively: stomach palpation
reveals painfulness in the gastroduodenal area. Electrophasoduodenoscopy revealed a
5 mm ulcer on the anterior wall of duodenum. Urease test is positive What is the
most probable leading mechanism of disease development?
+ Helicobacterial infection
- Dietary allergy
- Autoantibody production
-Reduced prostaglandin synthesis
- Disorder of gastric motor activity

?In order to prevent wound infection associated with surgical procedures a patient
was given a synthetic antiprotozoan drug with a high activity against Helicobacter
pylori. Specify this drug:
+ Metronidazole
- Doxycycline hydrochloride
- Chingamin
-Acyclovir
- Isoniazid

?A 6-year-old child has duodenal ulcer. What antibacterial drug should be co-
administered together with metronidazole and De-Nol in order to eradicate
Helicobacter pylori infection?
+ Amoxicillin
- Tetracycline
- Oleandomycin
-Biseptol
- Sulfadimethoxinum

?A 40 year old man noticed a reddening and an edema of skin in the area of his neck
that later developed into a small abscess. The incised focus is dense, yellowish-
green. The pus contains white granules. Histological examination revealed drusen of
a fungus, plasmatic and xanthome cells, macrophages. What type of mycosis is the
most probable?
+ Actinomycosis
- Aspergillosis
- Candidosis
-Sporotrichosis
- Coccidioidomycosis

?A 40-year-old man developed skin redness and an swelling in the neck area, where
eventually a small abscess appeared. The section the focus is dense and yellow-
green colored. In the purulent masses there are white granules. Histologically
there are fungal druses, plasma and xanthome cells, and macrophages detected.
Specify the most correct etiological name of this pathological process?
+ Actinomycosis
- Furuncle
- Carbuncle
-Syphilis
- Leprosy

?Microscopical examination of an infiltrate removed from the submandibular skin

area of a 30 y.o. man revealed foci of purulent fluxing surrounded by maturing
granulations and mature connective tissue, the pus contains druses consisting of
multiple short rod-like elements with one end attached to the homogenous centre.
What disease is it?
+ Actinomycosis
- Tuberculosis
- Syphilis
-Candidosis
- �

?A 32-year-old patient who lives in the countryside consulted a doctor about a

painful swelling and a fistula in the submandibular region. Examination revealed an
infiltration with a fistula discharging thick pus and containing white granules. On
dissection the infiltration tissues turned out to be dense, yellow-green and had
honeycomb structure because of multiple abscesses. What is the most likely
diagnosis?
+ Actinomycosis
- Tuberculosis
- Lepra
-Syphilis
- Submandibular abscess

?Microscopic examination of pus sample taken from mandibular fistula canal and
stained by Gram�s method has revealed druses with gram-positive coloring in the
center and cone-shaped structures with gram-negative coloring. Such morphology is
characteristic of the agent of:
-Fusobacteriosis
+Actinomycosis
- Staphylococcal osteomyelitis
-Anaerobic infection
- Candidiasis

?A 3 month old infant has got a white deposition on the mucous membrane of his
mouth, tongue and lips. The doctor suspected candidosis. What nutrient medium
should be used for inoculation of the material under examination in order to
confirm this diagnosis?
+ Sabouraud
- Endo
- Loewenstein-Jensen
-Roux
- Clauberg

?A 3 m.o. baby has white film on the mucous membrane of his mouth, tongue and lips.
A doctor suspected candidosis. What nutrient medium should be applied for
inoculation of the material under examination in order to confirm this diagnosis?
+ Sabouraud�s
- Endo
- Jensen�s
-Roux
- Clauberg�s

?Examination of a child revealed some whitish spots looking like coagulated milk on
the mucous membrane of his cheeks and tongue. Analysis of smears revealed gram-
positive oval yeast-like cells. What causative agents are they?
+ Candida
- Staphylococci
- Diphtheria bacillus
-Actinomycetes
- Fusobacteria

?During examination of a 3-month old infant a pediatrician revealed that the baby�s
oral mucosa and tongue were covered with a thick white deposit. In the material
taken from the affected site a bacteriologist revealed the presence of yeast fungi
giving the reasons for suspecting a fungal infection which occurs most often in
children of this age, namely:
+ Candidiasis
- Favus
- Epidermophytosis
-Actinomycosis
- Trichophytia

?Microscopic examination of a Gramstained scrape from patient�s tongue revealed

oval, round, elongated chains of dark-violet gemmating cells. What disease can be
caused by this causative agent?
+ Candidosis
- Actinomycosis
- Diphtheria
-Staphylococcic infection
- Streptococcic infection

?A 9 y.o. child has been taking antibiotics on account of bronchopneumonia for a

long time. There appeared pain and burning in the area of mucous membrane of his
lips and tongue. Objectively: mucous membrane of lips and tongue has caseous and
grey plaques that can be easily removed by a spatula leaving hyperemia foci on
their spot. Microscopic examination of the plaques revealed mycelium. What is the
most probable diagnosis?
+ Candidous cheilitis
- Exfoliative cheilitis
- Leukoplakia
-Contactant allergic cheilitis
- Manganotti�s Cheilitis

?After continuous treatment with antibiotics a patient got symptoms of stomatitis.

Examination of specimens of oral mucous membrane revealed some oval polymorphous
Gram-positive microorganisms arranged in clusters. What microorganism may be the
cause of such manifestations?
+ �.albicans
- -perfringens
- S.aureus
-S.pyogenes
- H.pylori

?After long-term antibiotic treatment a patient has developed whitish spots on the
oral mucosa. Gram-positive oval budding cells were detected in the smear
preparations. What causative agents were detected?
+ Candida fungi
- Staphylococci
- Sarcinae
-Actinomycete
- Tetracocci

?A 70-year-old man has developed prosphetic stomatitis. Apart of this he was found
to have an evident lesion of mouth corners. Microscopical examination revealed
large ovoid gram-positive cells. What microorganisms are most likely to be the
leading etiological agent of such a lesion?
+ Candida fungi
- Streptococci
- Staphylococci
-Neisseria
- Corynebacteria

?An 18-year-old patient has developed candidiasis after the case of pneumonia
treated with ?-lactam antibiotic. What antimycotic agent should be prescribed?
+ Fluconazole
- Streptomycin
- Phthalylsulfathiazole
-Ampicillin
- Trimethoprim/sulfamethoxazole

?A patient who has been taking tetracycline for a long time has developed
candidosis of mucous membranes. What drug shoul administered for its treatment?
+ Itraconazole
- Griseofulvin
- Nitrofungin
-Amphotericin
- Nitrofurantoin

?A female who had been continuously taking antibiotics for an intestinal infection
developed a complication manifested by inflammation of the oral mucosa and white
deposit. Bacteriological study of the deposit samples revealed yeast fungi Candida
albicans. Which of the following medications is indicated for the treatment of this
complication?
+ Fluconazole
- Biseptol
- Tetracycline
-Furazolidone
- Polymyxin

?A pregnant woman complains of vaginal mucosa irritation, itching and genital

tracts secretion. Bacterioscopy of vaginal smears revealed large gram-positive oval
oblong cells that form pseudomicelium. What is the most probable channel of
infection?
+ Endogenous infection
- Sexual transmission
- Contact infection
-Vector-borne transmission
- Wound infection

?A patient with skin mycosis has disorder of cellular immunity. The most typical
characteristic of it is reduction of the following index:
+ T-lymphocytes
- Immunoglobulin G
- Immunoglobulin E
-B-lymphocytes
- Plasmocytes

?In order to establish the possible contamination of a medication with fungi, a

nutrient medium was inoculated, which resulted in growth of large cream-like
colonies. What nutrient medium was used in this case?
+ Sabouraud
- Lowenstein- Jensen
- Roux
-Loeffler
- Finn-2

?Crude herbal drugs must be examined for yeast-like fungi. What agar can ensure
development of these microorganisms so that associating microflora will grow very
slowly or won�t grow at all?
+ Sabouraud�s peptone agar
- Endo agar
- Milk-salt agar
-Meat infusion agar
- Blood agar

?What preparations are used for prevention of fungal infection?

+ Fluconozol, Orungal, Nisoral
- Rubomycin, Bleomycin, Mytomycin C
- Cytosar, Cormyctin, Lomycitin
-Captopril, Enalapril
- Isoniazid, Ftibazid, Pyrazinamid
?Name the halogen-containing antiseptic with fungicidal properties, which is used
to treat dermatomycosis:
+ Iodine solution
- Formalin solution
- Methylene blue
-Brilliant green
- Boric acid solution

?During the regular sanitary epidemiological inspection of a pharmacy, the

bacteriological analysis of air was performed. The air was found to have bacilli,
yeast fungi, hemolytic streptococci, micrococci. Which of the detected
microorganisms indicate the direct epidemic danger?
+ Haemolytic streptococci
- Micrococci
- Bacilli
-Yeast fungi
- �

?Presence of pathogenic microorganisms in the air can be detected by presence of

sanitary representative bacteria. Choose bacteria that are indicators of direct
epidemiological danger:
+Hemolytic streptococci
-Sarcina
-Molds
-Yeast
-Micrococci

? Sanitary microbiological analysis of the indoor air of a pharmacy carried out in

summer revealed presence of Streptococcus haemolyticus and Streptococcus viridians
at the rate of 40 microorganisms per 1 m3. Specify the microbiological
characteristic of the air:
+ Contaminated
- Within the permissible limits
- Almost pure
-Pure
- These microorganisms are not the indexes of the air quality

?Sanitary and bacteriological examination of air in drug-store premises revealed

increased content of sanitary representative microorganisms. What microorganisms
are these?
+ Golden staphylococcus and hemolytic streptococcus
- Diphtheria and tuberculosis bacilli
- Colon and blue pus bacilli
-Epidermal staphylococcus and sarcina
- Enterococci and citrobacter

?During sanitary and bacteriological examination of air in a drugstore it was

revealed that the air had high concentration of sanitary meaningful microorganisms.
What microorganisms are these?
+ Staphylococcus aureus and hemolytic streptococcus
- Diphtheritic and tuberculous bacilli
- Colibacilli and blue pus bacilli
-Epidermal staphylococcus and Sarcina
- Enterococci and Citrobacter

?Sanitary-biologic examination of air in a drugstore revealed a sanitary-indicative

microorganism. Name it:
+ Staphylococcus aureus
- Colon bacillus
- Fecal enterococcus
-?-haemolytic streptococcus
- Citrobacter

?Routine investigation of microbiological sanitary condition of air in a hospital

is performed once in 3 months. What microorganism is the sanitary indicator of air
condition in an enclosed space?
+ S.aureus
- E coli
- E faecalis
-P.aeruginosa
- C perfringens

?Sanitary bacteriological research on water by the membrane filter method revealed

two red colonies on a membrane filter (Endo agar) through which 500 ml of analyzed
water were passed. Calculate the coli index and coli titer of the analyzed water:
+ 4 and 250
-2 and 500
-250 and 4
-500 and 2
-250 and 2

?During sanitary and bacteriological testing of water with the membrane filter
technique there were revealed two red colonies on a membrane filter (Endo agar)
through which 500 ml of water was filtred. Calculate the coli index and coli titer
of the analyzed water:
+ 4 and 250
-2 and 500
-250 and 4
-500 and 2
-250 and 2

?After the sanitary and bacteriological study of tap water the following results
were obtained: the total number of bacteria in 1,0 ml was 80, coli index was 3. How
would you interpret the study results?
+ Water is safe to be consumed
- Water is of doubtful quality
- Water is of highly doubtful quality
-Water is contaminated
- Water is highly contaminated

? Bacteriological analysis of tap water has resulted in the following: total

bacterial count in 1,0 ml of water is 80, coli index is 3. What would be the
conclusion?
+ The water is safe for consumption
- The water quality is doubtful
- The water is extremely polluted
-The water quality is extremely doubtful
- The water is polluted

?After the water supply system had been put into operation in a new residential
area, the medical officers of sanitary and epidemiological station measured total
microbial number in the water. Name the maximum permissible value of this indicator
for potable water:
-1000.
- 500.
- 400.
+ 100.
- 10.

?A laboratory received a sample of water used in drug production for sanitary and
viral analysis. What group of viruses will indicate fecal contamination of water
and thus the need for its additional purification?
+ Picornaviridae
- Herpesviridae
- Flaviviridae
-Retroviridae
- Orthomyxoviridae

?In an urban settlement situated on the riverbank, an outbreak of hepatitis A was

registered. The disease might have water origin. This assumption can be confirmed
by growth of the following values of water quality:
+ Number of coli-phages
- Escherichia coli index
- Oxidability
-Index of fecal coli-forms
- Presence of benign leptospirosis pathogen

?Basing upon the data of laboratory assessment of sanitary state of soil in a

certain territory, the soil was found to be low-contaminated according to the
sanitary indicative value; contaminated according to the coli titer; low-
contaminated according to the anaerobe titer (C perfringens). This is indicative
of:
+ Fresh fecal contamination
- Old fecal contamination
- Insufficient intensity of soil humification
-Constant entry of organic protein contaminations
- Insufficient insolation and aeration of soil