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STS L 3.2 With Answers

This document discusses gene therapy and its various forms. It begins by naming diseases that have become obsolete due to medical advances like polio, guinea worm disease, and measles. The document then discusses why some diseases like cancer and HIV remain incurable and explains gene therapy is an experimental technique that uses genes to treat diseases. It describes two main techniques: gene augmentation therapy which adds a functional gene to replace a missing protein, and gene inhibition therapy which introduces a gene to inhibit the expression of another gene. The document differentiates somatic and germline gene therapy based on the type of cells treated.

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82 views4 pages

STS L 3.2 With Answers

This document discusses gene therapy and its various forms. It begins by naming diseases that have become obsolete due to medical advances like polio, guinea worm disease, and measles. The document then discusses why some diseases like cancer and HIV remain incurable and explains gene therapy is an experimental technique that uses genes to treat diseases. It describes two main techniques: gene augmentation therapy which adds a functional gene to replace a missing protein, and gene inhibition therapy which introduces a gene to inhibit the expression of another gene. The document differentiates somatic and germline gene therapy based on the type of cells treated.

Uploaded by

Vhince Pisco
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 4

JANN MC NAMRA C.

PISCO,II
BSHM 3C
GE 117
Lesson 2
TITLE: The Aspects of Gene Therapy

ACTIVITY

NAME IT:

Name at least 5 diseases that were considered as obsolete (non-existing) because of


medical breakthrough.

1) POLIO
2) GUINEA WORM DISEASE
3) LYMPHATIC FILARIASIS
4) MEASLES
5) CYSTICERCOSIS
ANALYSIS

Despite the advancement of science, why is it that there are some diseases like cancer and
HIV, are still considered as incurable?

There are many conditions that, while incurable, will still allow the person to live a
long, full life. Conditions like diabetes, asthma and a variety of mental illnesses,
including Alzheimer’s and other forms of dementia, cannot be “cured,” but they can
be managed. No cure exists for HIV/AIDS, but medication exists that can help control
the symptoms of it and Cancer Metastatic cancer is typically incurable, although
treatment can extend a patient’s life.

1
APPLICATION

DISCUSSION

You will be evaluated using the rubric below;

Description
Score Understanding Strategies Thinking Skills
Uses effective
Understanding of Uses logical thinking
4 strategies to get
concept is clearly evident to arrive at conclusion
accurate results
Uses appropriate
Understanding of the
strategies to arrive Shows thinking skills
3 concept is evident
at a result to arrive at conclusion

Has limited
Uses strategies Attempts to show
2 understanding of a
that are ineffective thinking skills
concept

Has a complete lack of Makes no attempt Shows no


1
understanding of concept to use a strategy understanding

What is gene therapy? What are the other various forms of gene therapy? Explain each.

Gene therapy is an experimental technique that uses genes to treat or prevent


disease. In the future, this technique may allow doctors to treat a disorder by
inserting a gene into a patient’s cells instead of using drugs or surgery.

There are several techniques for carrying out gene therapy. These include:

2
Gene augmentation therapy

 This is used to treat diseases caused by a mutation that stops a gene from
producing a functioning product, such as a protein?.
 This therapy adds DNA containing a functional version of the lost gene back
into the cell.
 The new gene produces a functioning product at sufficient levels to replace
the protein that was originally missing.
 This is only successful if the effects of the disease are reversible or have not
resulted in lasting damage to the body.
 For example, this can be used to treat loss of function disorders such as
cystic fibrosis by introducing a functional copy of the gene to correct the
disease.

Gene inhibition therapy

 Suitable for the treatment of infectious diseases, cancer and inherited disease
caused by inappropriate gene activity.
 The aim is to introduce a gene whose product either:
 Inhibits the expression of another gene
 Interferes with the activity of the product of another gene.
 The basis of this therapy is to eliminate the activity of a gene that encourages
the growth of disease-related cells.

SOURCE: (https://www.yourgenome.org/facts/what-is-gene-therapy)

Should gene therapy be limited to medical concerns only or could it be used for aesthetic
purposes?

Gene therapy can be used for aesthetics along with medical purposes. Gene therapy
refers to the insertion of genes to treat disorders, which can not be treated
otherwise. Example of disorders which can be treated is cancer, cystic fibrosis etc.
Gene therapy also finds its applications for aesthetic purposes. The area includes
the beautification of humans. The application can be in the form of plastic surgery,
production of designer babies. Though the use may remain limited for some time in
future too, due to ethical purposes and unorganized management to control black
marketing of confidential data. Misuse of therapy may also harm humans

Differentiate the two forms of gene therapy.

3
There are two different types of gene therapy depending on which types of cells
are treated:

 Somatic gene therapy: transfer of a section of DNA to any cell of the body that
doesn’t produce sperm or eggs. Effects of gene therapy will not be passed onto
the patient’s children.

 Germline gene therapy: transfer of a section of DNA to cells that produce eggs
or sperm. Effects of gene therapy will be passed onto the patient’s children and
subsequent generations.

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