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Generic Drugs

This document provides dosing information for several generic medications: 1) Acetaminophen is used to relieve minor aches and pains and reduce fever. Dosing is weight-based for children under 12 and fixed dosing for those ages 6-12, not to exceed certain daily amounts. 2) Atomoxetine is used to treat ADHD and helps increase attention and focus. Dosing starts at 40mg daily for adults and is weight-based for pediatric patients, not exceeding certain daily maximums. 3) Bearberry is used as a urinary tract antibacterial and astringent, though long-term safety is unclear. Dosing involves dried herb, tea, or fluid extract up to
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0% found this document useful (0 votes)
58 views5 pages

Generic Drugs

This document provides dosing information for several generic medications: 1) Acetaminophen is used to relieve minor aches and pains and reduce fever. Dosing is weight-based for children under 12 and fixed dosing for those ages 6-12, not to exceed certain daily amounts. 2) Atomoxetine is used to treat ADHD and helps increase attention and focus. Dosing starts at 40mg daily for adults and is weight-based for pediatric patients, not exceeding certain daily maximums. 3) Bearberry is used as a urinary tract antibacterial and astringent, though long-term safety is unclear. Dosing involves dried herb, tea, or fluid extract up to
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Generic

Monica name A. Bullecer Description


Joeanne Dosage 12 - STC
Acetaminophen Acetaminophen is an analgesic (Weight based dosing) Children under 12 years: 10-15
used to temporarily relieve minor mg/kg/dose taken orally once every 4-6 hours; not to
aches and pains due to headache, exceed 5 doses in 24 hours
muscular aches, backache, minor Fixed dosing
pain of arthritis, the common cold, (Fixed dosing) Children under 6 years: Ask a healthcare
toothache, and premenstrual and provider
menstrual cramps. Acetaminophen Children 6-12 years: 325 mg orally once every 4-6 hours;
is also used to temporarily reduce not to exceed 1.625 g/day for not more than 5 days unless
fever. directed by a healthcare provider
Children under 12 years and older:
Regular strength: 650 mg once every 4-6 hours; not to
exceed 3.25 g in 24 hours; under supervision of healthcare
professional, doses of up to 4 g/day may be used
Extra strength: 1000 mg once every 6 hours; not to
exceed 3 g in 24 hours; under supervision of healthcare
professional, doses of up to 4 g/day may be used
Extended-release: 1.3 g once every 8 hours; not to exceed
3.9 g in 24 hours
Atomoxetine Atomoxetine is used to treat Adult: 40 mg orally once daily initially; increased after 3
attention-deficit hyperactivity days or more to 80 mg orally once daily or divided every
disorder (ADHD) as part of a total 12 hours; may be increased to up to 100 mg if optimal
treatment plan, including response is not achieved
psychological, social, and other Dosing considerations
treatments. Atomoxetine may help When drug is coadministered with strong CYP2D6
to increase the ability to pay inhibitors (e.g., paroxetine, fluoxetine, quinidine) or used
attention, concentrate, stay in patients known to be poor CYP2D6 metabolizers,
focused, and stop fidgeting. It is decrease dosage; initiate with 40 mg/day, but do not
thought to work by restoring the exceed 80 mg/day
balance of certain natural Pediatric:
substances (neurotransmitters) in Children over 6 years and up to 70 kg: 0.5 mg/kg orally
the brain. once daily; increased after 3 days or more to target dosage
of approximately 1.2 mg/kg orally once daily or divided
every 12 hours; total daily dose not to exceed 1.4 mg/kg or
100 mg, whichever is less; no benefit observed with
higher doses
Greater than 70 kg: 40 mg orally once daily initially;
increased after 3 days or more to 80 mg orally once daily
or divided every 12 hours; if necessary, may be increased
after 2-4 additional weeks to 100 mg orally once daily
Dosing considerations
When drug is coadministered with strong CYP2D6
inhibitors (e.g., paroxetine, fluoxetine, quinidine) or used
in patients known to be poor CYP2D6 metabolizers,
decrease dosage
Up to 70 kg: 0.5 mg/kg/day initially; increased to usual
target dosage of 1.2 mg/kg/day only if symptoms fail to
improve after 4 weeks and initial dosage is well tolerated
Greater than 70 kg: 40 mg/day initially; not to exceed 80
mg/day
Bearberry Bearberry is used as a urinary tract Dried herb
antibacterial and astringent. 1.5-4 g orally once daily
Bearberry is possibly effective for Tea
urinary tract inflammation. One cup of tea orally once daily
Currently it is not clear if bearberry Steep 3 grams dried leaf in 150 mL cold water for 12-24
extended use is safe. Patients are hours and then strain
advised not to use it long-term. Fluid extract (1:1 in 25% alcohol)
1.5-4 mL orally three times daily
Hydroquinone derivative, calculated as water-free
arbutin
100-210 mg orally once daily
Clobetasol Clobetasol is a prescription topical Corticosteroid-responsive Dermatoses
steroid used to treat the Adult: Cream/foam: apply a thin layer to affected areas
inflammation and itching caused every 12 hours and rub in gently and completely; not to
by a number of skin conditions exceed 50 g/week
such as allergic reactions, eczema, Pediatric:
and psoriasis. Clobetasol is a very Children under 12 years old: safety and efficacy not
strong (super-high-potency) established
corticosteroid. Children over 12 years: cream/foam: apply a thin layer to
affected areas every 12 hours and rub in gently and
completely, not to exceed 50 g/week
Scalp Psoriasis
Adult: Shampoo: Apply a thin film to dry scalp once a
day; leave in place for 15 minutes, add water, lather, and
then rinse thoroughly
Pediatric:
Children under 12 years old: safety and efficacy not
established
Children over 12 years: shampoo: apply a thin film to
dry scalp once per day; leave in place for 12 minutes; add
water, lather, and then rinse thoroughly
Mild to Moderate Plaque-type Psoriasis of Nonscalp
Areas
Adult: Foam: Apply to the affected area in scalp every 12
hours for up to 2 weeks; not to exceed 50 g/week
Pediatric:
Children under 12 years old: safety and efficacy not
established
Children over 12 years old: foam: Apply to the affected
area in scalp every 12 hours for up to 2 weeks; not to
exceed 50 g/week
Moderate to Severe Plaque-type Psoriasis
Emollient/cream/lotion: Apply to the affected area in
scalp every 12 hours for up to 2 weeks if the area is less
than 10% of the body surface area; not to exceed 50
g/week
Spray: Apply by spraying onto affected area every 12
hours; rub into the skin; should not be used for more than
4 weeks
Deferasirox Deferasirox is a prescription Transfusional Hemosiderosis
medication used for the treatment Adult dosage
of transfusional hemosiderosis and  Exjade: 20 mg/kg orally every day; may increase
non-transfusion-dependent
thalassemia. by 5- to 10-mg increments based on serum ferritin;
if not controlled on 30 mg/kg/day (ie, serum
ferritin persistently above 2500 mcg/L), may
increase up to 40 mg/kg every day
 Jadenu: 14 mg/kg orally every day (round to
nearest whole tablet); adjust dose in 3.5-7 mg/kg
according to response and goals; if not adequately
controlled on 21 mg/kg/day (serum ferritin levels
persistently above 2500 mcg/L), may increase to
28 mg/kg/day; do not exceed 28 mg/kg
Pediatric dosage
 Children below 2 years: Safety and efficacy not
established
Children above 2 years
 Exjade: 20 mg/kg orally every day; may increase
by 5- to 10-mg increments based on serum ferritin;
if not controlled on 30 mg/kg/day (ie, serum
ferritin persistently above 2500 mcg/L), may
increase up to 40 mg/kg every day
 Jadenu: 14 mg/kg orally every day (round to
nearest whole tablet); adjust dose in 3.5-7 mg/kg
according to response and goals; if not adequately
controlled with doses of 21 mg/kg/day (serum
ferritin levels persistently above 2500 mcg/L), may
increase up to 28 mg/kg/day ; do not exceed 28
mg/kg
Nontransfusion-Dependent Thalassemia
Adult dosage
 Exjade: 10 mg/kg orally every day (calculate dose
to nearest tablet size); if LIC above 15 mg Fe/g dw
after 4 weeks, consider increasing dose by 5-10
mg/kg up to 20 mg/kg/day
 Jadenu: 7 mg/kg orally every day (calculate dose
to nearest whole tablet); if LIC above 7 mg Fe/g
dw after 6 months, increase dose by 3.5-7 mg/kg
up to 14 mg/kg/day; do not exceed 14 mg/kg/day
Pediatric dosage
Children below 10 years: Safety and efficacy not
established
Children above 10 years
 Exjade: 10 mg/kg orally every day (calculate dose
to nearest tablet size); if LIC above 15 mg Fe/g dw
after 4 weeks, consider increasing dose by 5-10
mg/kg up to 20 mg/kg/day
 Jadenu: 7 mg/kg orally every day (calculate dose
to nearest whole tablet); if LIC above 7 mg Fe/g
dw after 6 months, increase dose by 3.5-7 mg/kg
up to 14 mg/kg/day; do not exceed 14 mg/kg/day
Elderberry Elderberry suggested uses include Syrup
for treatment and prevention of the Adult: 15 mL (1 tablespoon) orally four times daily for 3-
common cold, cough and flu 5 days (Sambucol, Nature's Way)
symptoms, sinusitis, as an Children: 15 mL (1 tablespoon) orally twice daily for 3
immunostimulant, and treating days
mouth ulcers and tonsillitis. Other Lozenge
uses for elderberry extract include 175 mg orally four times daily for 2 days
reducing the damaging effects of Topical
LDL cholesterol, and protection as Leaves are used for bruises, sprains, wounds, and burns
an antioxidant. Suggested uses for
elderberry leaves for topical
application includes treatment of
bruises, sprains, wounds, burns and
chilblains, and as mouthwash for
mouth ulcers. Suggested uses for
elderberry tincture are for
rheumatic conditions, and
suggested uses for elderberry oil
are for painful joints.
Ferrous sulfate Ferrous sulfate is an iron  Children 0-6 months: 0.27 mg/day
supplement used to treat or prevent  Children 6-12 months: 11 mg/day
low blood levels of iron (e.g., for  Children 1-3 years: 7 mg/day
anemia or during pregnancy). Iron  Children 3-8 years: 10 mg/day
is an important mineral that the  Children 8-13 years: 8 mg/day
body needs to produce red blood  Children over 13 years:
cells and keep you in good health. o Males: 11 mg/day
o Females: 15 mg/day
o Pregnant females: 27 mg/day
o Lactating females: 10 mg/day
 Adults 19-50 years:
o Males: 8 mg/day
o Females: 18 mg/day
o Pregnant females: 27 mg/day
o Lactating females: 9 mg/day
 Adults over 50 years: 8 mg/day

Minoxidil Minoxidil is indicated only in the Severe or Refractory Hypertension (HTN)


treatment of hypertension that is  Adult, Initial: 5mg orally once/day, increase every
symptomatic or associated with 3 days as needed
target organ damage and is not  Adult, Maintenance: 2.5-80 mg/day once/day or
manageable with maximum every 12 hours; not to exceed 100 mg/day
therapeutic doses of a diuretic plus  Children under 12 years
two other antihypertensive drugs. Children over 12 years
At present use in milder degrees of  Initial: 5mg orally once/day, increase every 3 days
hypertension is not recommended as needed
because the benefit-risk  Maintenance: 2.5-80 mg/day once/day or every 12
relationship in such patients has hours; not to exceed 100 mg/day
not been defined. Geriatric: 2.5 mg orally once/day; titrate to response
gradually
Quercetin Quercetin suggested uses include Suggested Dosing
for seasonal allergies, prevention  400-500 mg orally three times daily
of diabetic cataracts, viral  Prostatitis: 500 mg orally twice daily
infections, cardiovascular disease,  Cancer: 420-1400 mg/m2 intravenous (IV) bolus
as adjunctive therapy in cancer, to once/week
treat chronic prostatitis, and
interstitial cystitis.
Xylometazoline Xylometazoline, also spelled Adult and pediatric dosage
xylomethazoline, is a medication Nasal drops/spray
used to reduce symptoms of nasal  0.05%
congestion, allergic rhinitis, and Nasal Congestion
sinusitis. Adult dosage
 Aged below 12 years: Not recommended
 Aged above 12 years: 0.05% Spray (2-3
drops/sprays) per nostril every 8-10 hours; no more
than 3 doses/day

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