2/18/23, 5:47 PM Post-Review Exam - Anti-Infectives - Feb 18, 2023 - 11:30 AM to 12 Noon: Attempt review

Dashboard My courses CA Pharmacology BCA Review FEB-MARCH2023

Post-Review Exam - Anti-Infectives - Feb 18, 2023 - 11:30 AM to 12 Noon

Started on Saturday, 18 February 2023, 11:21 AM

State Finished
Completed on Saturday, 18 February 2023, 11:38 AM
Time taken 16 mins 49 secs
Grade 25.00 out of 25.00 (100%)

Question 1
Correct

Mark 1.00 out of 1.00

Which macrolide can be given as a single dose in the management of non-gonococcal urethritis?

a. Clarithromycin

b. Erythromycin

c. Azithromycin 

The correct answer is: Azithromycin

Question 2
Correct

Mark 1.00 out of 1.00

The following antifungal agents are used primarily for dermatophytic infections EXCEPT

a. Nystatin

b. Caspofungin 

c. Terbinafine

d. Griseofulvin

The correct answer is:

Caspofungin

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Question 3

Correct

Mark 1.00 out of 1.00

Which of the following pairs of protein synthesis inhibitors is generally bacteriostatic?

a. Aminoglycosides and Tetracyclines

b. Tetracyclines and Linezolid 

c. Aminoglycosides and Linezolid

The correct answer is:

Tetracyclines and Linezolid

Question 4
Correct

Mark 1.00 out of 1.00

Which of the following are useful for prophylaxis against influenza A and B?

a. Oseltamivir 

b. Ribavirin

c. Ganciclovir

d. Amantadine

The correct answer is:

Oseltamivir

Question 5
Correct

Mark 1.00 out of 1.00

This antifungal is a CYT P450 enzyme inducer.

a. Ketoconazole

b. Anidulafungin

c. Flucytosine

d. Griseofulvin 

The correct answer is:

Griseofulvin

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Question 6

Correct

Mark 1.00 out of 1.00

The following protein synthesis inhibitors binds to the 30S bacterial ribosomal subunit EXCEPT?

a. Amikacin

b. Tetracycline

c. Chloramphenicol 

d. Doxycycline

The correct answer is:

Chloramphenicol

Question 7
Correct

Mark 1.00 out of 1.00

The following antibiotics are part of the oral antibiotic therapy against Helicobacter pylori EXCEPT

a. Amoxicillin

b. Clarithromycin

c. Cefuroxime 

d. Tetracycline
e. Metronidazole

The correct answer is:

Cefuroxime

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Question 8

Correct

Mark 1.00 out of 1.00

Pyrimethamine + sulfadiazine is a drug regimen used in the treatment of

a. Toxoplasmosis 

b. Trichomoniasis

c. Amebiasis

d. Giardiasis

The correct answer is:

Toxoplasmosis

Question 9
Correct

Mark 1.00 out of 1.00

The following antimalarials are considered safe in patients with G6PD deficiency EXCEPT

a. Atovaquon

b. Halofantrine

c. Artemisinin derivatives

d. Primaquine 

The correct answer is:

Primaquine

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Question 10

Correct

Mark 1.00 out of 1.00

This antimalarial agent acts by blocking DNA replication and transcription to RNA. It is associated with cinchonism
as an adverse effect.

a. Chloroquine

b. Quinine 

c. Primaquine

d. Atovaquone + proguanil

The correct answer is:

Quinine

Question 11
Correct

Mark 1.00 out of 1.00

This antimalarial agent inhibits mitochondrial electron transport and folate metabolism.

a. Atovaquone-proguanil 

b. Primaquine

c. Mefloquine

d. Doxycycline

The correct answer is:

Atovaquone-proguanil

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Question 12

Correct

Mark 1.00 out of 1.00

Which of the following antiviral agents inhibits viral DNA polymerase but DOES NOT cause chain termination when
incorporated into DNA?

a. Ganciclovir 

b. Acyclovir

c. Famciclovir

The correct answer is:

Ganciclovir

Question 13
Correct

Mark 1.00 out of 1.00

Among the following antifungals, which is used only for dermatophytes?

a. Amphotericin B

b. Flucytosine

c. Griseofulvin 

The correct answer is:

Griseofulvin

Question 14
Correct

Mark 1.00 out of 1.00

Ceftaroline is a ______ generation cephalosporin.

a. 2nd

b. 5th 

c. 1st

d. 3rd

e. 4th

The correct answer is:

5th

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Question 15

Correct

Mark 1.00 out of 1.00

This antifungal agent inhibits fungal cytochrome P450. It is also associated with gynecomastia as an adverse
effect.

a. Griseofulvin

b. Amphotericin B

c. Ketoconazole 

d. Flucytosine

The correct answer is:

Ketoconazole

Question 16
Correct

Mark 1.00 out of 1.00

Which of the following classes of reverse transcriptase inhibitors requires bioactivation?

a. Non-nucleoside reverse transcriptase inhibitors

b. Nucleoside reverse transcriptase inhibitors 

The correct answer is:

Nucleoside reverse transcriptase inhibitors

Question 17
Correct

Mark 1.00 out of 1.00

In the management of HIV, this agent inhibits integrase.

a. Enfuvirtide

b. Maraviroc

c. Raltegravir 

d. Ritonavir

The correct answer is:

Raltegravir

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Question 18

Correct

Mark 1.00 out of 1.00

Penicillin G is the drug of choice for prophylaxis in

a. Rheumatic fever 

b. Infective endocarditis

c. Recurrent otitis media

d. Pneumocystis carinii pneumonia

The correct answer is:

Rheumatic fever

Question 19
Correct

Mark 1.00 out of 1.00

The drug of choice for cysticercosis and hydatid disease is

a. Niclosamide

b. Albendazole 
c. Metrifonate

d. Praziquantel

The correct answer is: Albendazole

Question 20
Correct

Mark 1.00 out of 1.00

Fluoroquinolones should not be given during pregnancy because it

a. Is ototoxic

b. Is mutagenic via the Ames test

c. Has deleterious effects on collagen metabolism 

d. Causes cholestasis in pregnancy

The correct answer is:

Has deleterious effects on collagen metabolism

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2/18/23, 5:47 PM Post-Review Exam - Anti-Infectives - Feb 18, 2023 - 11:30 AM to 12 Noon: Attempt review

Question 21

Correct

Mark 1.00 out of 1.00

This antifungal inhibits Inhibits squalene epoxidase.

a. Griseofulvin

b. Terbinafine 

c. Nystatin

d. Caspofungin

The correct answer is:

Terbinafine

Question 22
Correct

Mark 1.00 out of 1.00

Which adverse effect is common to all nucleoside reverse transcriptase inhibitors?

a. Disorders of lipid and carbohydrate metabolism

b. Lactic acidosis 

c. Severe hypersensitivity

d. Bone marrow suppression

The correct answer is:

Lactic acidosis

Question 23
Correct

Mark 1.00 out of 1.00

After prolonged clindamycin therapy, a patient developed pseudomembranous colitis. You decide to give
vancomycin orally. Is systemic absorption significant?

a. Yes

b. No 

The correct answer is:

No

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Question 24

Correct

Mark 1.00 out of 1.00

The following antihelminthics act by GABA receptor activation leads to paralysis and expulsion of worms EXCEPT

a. Ivermectin

b. Pyrantel pamoate 

c. Piperazine

The correct answer is:

Pyrantel pamoate

Question 25
Correct

Mark 1.00 out of 1.00

Antacids may decrease the oral bioavailability of the following EXCEPT

a. Azole antifungals

b. Tetracyclines
c. Fluoroquinolones

d. Amoxicillin 

The correct answer is:

Amoxicillin

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