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Hepatitis B Quiz

The document discusses recommendations from the CDC Advisory Committee on Immunization Practices regarding hepatitis B vaccination and screening. It provides guidance on prophylactic hepatitis B immune globulin administration for newborns, antiviral treatment during pregnancy, and viral load thresholds for treatment initiation. Recommendations are given for periodic monitoring of chronic hepatitis B patients on treatment and catch-up vaccination strategies.

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Bianca Watanabe - Ratilla
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234 views2 pages

Hepatitis B Quiz

The document discusses recommendations from the CDC Advisory Committee on Immunization Practices regarding hepatitis B vaccination and screening. It provides guidance on prophylactic hepatitis B immune globulin administration for newborns, antiviral treatment during pregnancy, and viral load thresholds for treatment initiation. Recommendations are given for periodic monitoring of chronic hepatitis B patients on treatment and catch-up vaccination strategies.

Uploaded by

Bianca Watanabe - Ratilla
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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1.

The following recommendations from the CDC Advisory Committee on Immunization


Practices (ACIP) as of February 2021 are TRUE, EXCEPT:

a. unvaccinated persons should complete a 3-dose series at 0, 1–2, 6 years


b. adolescents 11–15 years old may use an alternative 2-dose of adult recombinant
formulation schedule with at least 4 months between doses;
c. adolescents ≥ 18 years old may receive a 2-dose series of adjuvanted Hep B vaccine at
least 4 weeks apart;
d. adolescents ≥ 18 years old may receive the combined Hep A and Hep B vaccine as a 3-
dose series (0, 1, and 6 months) or 4-dose series (3 doses at 0, 7, and 21–30 days,
followed by a booster dose at 12 months)

2. A 23 year old G1P0 with unknown HBsAg status came in at the ER and was in active
labor. Upon giving birth, she asks if her child could be given prophylactic HBIG. What
would be your response?
a. Yes, we should definitely give your child HBIG in order to reduce maternal to child
transmission of Hepatitis B.
b. Yes, we should give you and your child prophylactic HBIG to decrease the risks of
hepatocellular carcinoma.
c. No, we should not give prophylactic HBIG to infants with mothers of unknown HBsAg
status.
d. None of the above.

3. Which of the following drugs can be given to pregnant patients with chronic hepatitis B
infection?
a. Entecavir
b. Tenofovir
c. Efavirenz
d. Lamivudine

4. Antiviral agents that inhibit HBV replication have been administered to pregnant women
with a high viral load and may reduce the risk of maternal to child transmission of
hepatitis B. What is the threshold of viral load wherein treatment may be initiated?
a. >= 100,000 IU/ml
b. >= 200,000 IU/ml
c. >= 300,000 IU/ml
d. >= 400,000 IU/ml

5. Which of the following statements regarding screening for hepatitis B is true?


a. Acceptance for HBV screening is high among pregnant patients.
b. All Filipinos should be screened for HBV using HBsAg and sonography.
c. In the Philippines, screening using rapid diagnostic tests is not considered cost effective
to prevent incurring chronic hepatitis B related medical expenses.
d. None of the above

6. In resource limited settings, which of the following can be used to guide initiation of
antiviral treatment in adults with chronic hepatitis B infection?
a. ALT elevated for 6 months with HBV DNA >= 200,000 IU/ml
b. Single elevated ALT and HBV DNA >= 2000 IU/ml
c. HBV DNA >= 200,000ml alone
d. None of the above

7. Among chronic hepatitis B patients with compensated liver cirrhosis on treatment, the
following are recommended for periodic monitoring EXCEPT:
a. HBV DNA
b. AFP
c. CEA
d. Creatinine

8. Which of the following is true regarding prophylactic HBIG administration?


a. For infants born to HBsAg positive mothers, HBV and HBIG 0.5ml should be administered
within 12 hours of life.
b. HBIG should not be administered later than 7 days, if not available immediately.
c. For infants born < 2kgs, the 1st dose received at birth is not counted as part of the
vaccine series. Additional 3 doses of HBV is needed.
d. All of the above.

9. Which of the following statements regarding catch up vaccination with HBV is true?
a. HBV catch-up vaccination among children 18 years old and younger with incomplete or
unknown HBV vaccination is recommended to decrease prevalence of HBsAg, HBV
detection, and increase anti-HBs seroconversion.
b. Catch up vaccination of healthy adults with no serological evidence of immunity ore
previous vaccination is recommended to decrease the incidence of acute hepatitis B.
c. Vaccination is recommended for pregnant women with no serological evidence of
immunity to prevent horizontal transmission. However, there is insufficient evidence
that this would decrease mother-to-child-transmission.
d. All of the above.

10. True or False. HBIG is only recommended for infants born to HBsAg positive mothers
True

Prepared by:
Dr. Bianca Watanabe – Ratilla
2nd Year, Resident

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