SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 1(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1. Product identifier

Trade name
CORRTREAT 12286
Material number: 252621
Chemical nature: Mixture of amine containing actives in solvents

1.2. Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses of the substance or mixture
Industry sector : Oilfield
Type of use : Corrosion inhibitor for the petroleum industry
Exposure scenarios: see annex

1.3. Details of the supplier of the safety data sheet

Identification of the company
Clariant (Gulf) FZE
PO Box 2326
Dubai
Information about the substance/mixture
BU Oil & Mining Services
Product Stewardship
e-mail: SDS.Europe@clariant.com

1.4. Emergency telephone number

00800-5121 5121 (24 h)

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008)
Acute toxicity, Category 4 H302: Harmful if swallowed.

Skin irritation, Category 2 H315: Causes skin irritation.

Serious eye damage, Category 1 H318: Causes serious eye damage.

Skin sensitisation, Category 1 H317: May cause an allergic skin reaction.

Specific target organ toxicity - repeated H373: May cause damage to organs through
exposure, Category 2 prolonged or repeated exposure.

Chronic aquatic toxicity, Category 2 H411: Toxic to aquatic life with long lasting effects.

2.2 Label elements

Labelling (REGULATION (EC) No 1272/2008)
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Hazard pictograms :

Signal word : Danger

Hazard statements : H302 Harmful if swallowed.

H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H373 May cause damage to organs through prolonged or
repeated exposure.
H411 Toxic to aquatic life with long lasting effects.

Precautionary statements :
Prevention:
P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/ eye protection/ face protection.
Response:
P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously
with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing. Immediately call a
POISON CENTER/doctor.
P314 Get medical advice/ attention if you feel unwell.
P333 + P313 If skin irritation or rash occurs: Get medical
advice/ attention.

Hazardous components which must be listed on the label:

Ethanediol

Amines, tallow alkyl, ethoxylated

2-Mercaptoethanol

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of
0.1% or higher.
No additional hazards are known except those derived from the labelling.

SECTION 3: Composition/information on ingredients

3.2 Mixtures
Hazardous components
Chemical name CAS-No. Classification Concentration
EC-No. (% w/w)
Registration number
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2-Butoxy ethanol 111-76-2 Acute Tox. 4; H302 15 - 25

203-905-0 Acute Tox. 4; H332
01-2119475108-36 Acute Tox. 4; H312
01-2119475108-36- Skin Irrit. 2; H315
0000 Eye Irrit. 2; H319
01-2119475108-36-
0004
01-2119475108-36-
0018
01-2119475108-36-
XXXX
Ethanediol 107-21-1 Acute Tox. 4; H302 10 - 15
203-473-3 STOT RE 2; H373
01-2119456816-28
01-2119456816-28-
0000
01-2119456816-28-
0003
01-2119456816-28-
0038
01-2119456816-28-
XXXX
Fatty acids, tall-oil, reaction 61790-69-0 Eye Irrit. 2; H319 20 - 25
products with diethylenetriamine 263-160-2 STOT SE 3; H335
Skin Irrit. 2; H315
Fatty amine ethoxylate 61791-44-4 Acute Tox. 4; H302 5 - 15
263-177-5 Aquatic Chronic 2;
H411
Eye Irrit. 2; H319
Skin Irrit. 2; H315
For explanation of abbreviations see section 16.

SECTION 4: First aid measures

4.1 Description of first aid measures

General advice : Remove/Take off immediately all contaminated clothing.

Protection of first-aiders : First Aid responders should pay attention to self-protection

and use the recommended protective clothing

If inhaled : In case of accident or if you feel unwell, seek medical advice

immediately (show the label where possible).

In case of skin contact : Wash with plenty of soap and water.

In case of eye contact : In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.

If swallowed : Do NOT induce vomiting.

Get medical advice/ attention.
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4.2 Most important symptoms and effects, both acute and delayed
Symptoms : Treat symptomatically.

Risks : No additional risks are known.

4.3 Indication of any immediate medical attention and special treatment needed
Treatment : Treat symptomatically.

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media : Use extinguishing measures that are appropriate to local
circumstances and the surrounding environment.

5.2 Special hazards arising from the substance or mixture

Specific hazards during : Carbon oxides
firefighting Nitrogen oxides (NOx)

5.3 Advice for firefighters

Special protective equipment : Self-contained breathing apparatus
for firefighters

Further information : Use extinguishing measures that are appropriate to local

circumstances and the surrounding environment.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Personal precautions : Wear suitable protective clothing.
Information regarding Safe handling, see chapter 7.

6.2 Environmental precautions

Environmental precautions : Do not empty into drains.

6.3 Methods and material for containment and cleaning up

Methods for cleaning up : Soak up with inert absorbent material and dispose of as
hazardous waste.

6.4 Reference to other sections

Information regarding Safe handling, see chapter 7., For personal protection see section 8., For
disposal considerations see section 13.
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SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling : Keep away from heat and sources of ignition.
Keep container in a well-ventilated place.
Take precautionary measures against static discharges.

Advice on protection against : Use only in well-ventilated areas. Store in a closed container.
fire and explosion

7.2 Conditions for safe storage, including any incompatibilities

Advice on common storage : Oxidizing agents

7.3 Specific end use(s)

Specific use(s) : No further recommendations.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure Limits
Components CAS-No. Value type (Form Control parameters Basis
of exposure)
2-Butoxy ethanol 111-76-2 TWA 20 ppm 2000/39/EC
98 mg/m3
Further information Identifies the possibility of significant uptake through the skin, Indicative
STEL 50 ppm 2000/39/EC
246 mg/m3
Further information Identifies the possibility of significant uptake through the skin, Indicative
Ethanediol 107-21-1 TWA 20 ppm 2000/39/EC
52 mg/m3
Further information Identifies the possibility of significant uptake through the skin, Indicative
STEL 40 ppm 2000/39/EC
104 mg/m3
Further information Identifies the possibility of significant uptake through the skin, Indicative
Derived No Effect Level (DNEL) according to Regulation (EC) No. 1907/2006:
Substance name End Use Exposure routes Potential health Value
effects
Ethanediol Workers Dermal Long-term systemic 106 mg/kg
CAS-No.: 107-21-1 effects bw/day
Remarks: DNEL
Workers Inhalation Long-term local 35 mg/m3
effects
Remarks: DNEL
General Dermal Long-term systemic 53 mg/kg
population effects bw/day
Remarks: DNEL
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General Inhalation Long-term local 7 mg/m3

population effects
Predicted No Effect Concentration (PNEC) according to Regulation (EC) No. 1907/2006:
Substance name Environmental Compartment Value
Ethanediol Fresh water 10 mg/l
CAS-No.: 107-21-1
salt water 1 mg/l
Water (intermittent release) 10 mg/l
Fresh water sediment 20,9 mg/kg dry
weight (d.w.)
Soil 1,53 mg/kg dry
weight (d.w.)
Sewage treatment plant 199,5 mg/l
8.2 Exposure controls
Personal protective equipment
Eye protection : Safety glasses with side-shields conforming to EN166

Hand protection
Remarks : Nitrile rubber gloves.

Skin and body protection : Wear suitable protective clothing.

Respiratory protection : In case of insufficient ventilation, wear suitable respiratory

equipment.

Filter type : Organic vapour type (A)

Use respiratory protection in case of insufficient exhaust

ventilation or prolonged exposure
Short term: filter apparatus, Filter A
Filter A or self-contained breathing apparatus

Protective measures : Remove/Take off immediately all contaminated clothing.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Appearance : Liquid

Colour : dark brown

Odour : characteristic

Odour Threshold : Not tested

pH : 7-8
Determined in the undiluted form

Melting point : not determined

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Boiling point : not determined

Flash point : > 93,4 °C

Evaporation rate : not determined

Upper explosion limit : Not applicable

Lower explosion limit : Not applicable

Relative vapour density : Not applicable

Density : 0,99 - 1,03 g/cm3 (25 °C)

Solubility(ies)
Water solubility : soluble

Partition coefficient: n- : Not applicable

octanol/water

Auto-ignition temperature : not tested.

Decomposition temperature : not tested.

Viscosity
Viscosity, dynamic : 50 - 100 mPa.s

Explosive properties : Not explosive

Oxidizing properties : The substance or mixture is not classified as oxidizing.

9.2 Other information

Particle size : Not applicable

SECTION 10: Stability and reactivity

10.1 Reactivity
See section 10.3. "Possibility of hazardous reactions"
10.2 Chemical stability
Stable under normal conditions.
10.3 Possibility of hazardous reactions
Hazardous reactions : None reasonably foreseeable.

10.4 Conditions to avoid

Conditions to avoid : Keep away from open flames, hot surfaces and sources of
ignition.

10.5 Incompatible materials

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Materials to avoid : Strong acids and strong bases

Strong oxidizing agents

10.6 Hazardous decomposition products

Carbon oxides, Nitrogen oxides (NOx)

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity
Product:
Acute oral toxicity : Remarks: not tested.

Acute inhalation toxicity : Remarks: not tested.

Acute dermal toxicity : Remarks: not tested.

Components:
2-Butoxy ethanol:
Acute oral toxicity : LD50 (Rat): 1.746 mg/kg

Acute toxicity estimate: 500 mg/kg

Method: Converted acute toxicity point estimate

Acute dermal toxicity : LD50 (Pig): 6.411 mg/kg

Acute toxicity estimate: 1.100 mg/kg

Method: Converted acute toxicity point estimate

Ethanediol:
Acute oral toxicity : LD50 (Rat, male and female): 22.000 mg/kg
Method: Other
GLP: no

Acute inhalation toxicity : LC50 (Rat, male and female): > 2,5 mg/l
Exposure time: 6 h
Method: Other
GLP: yes

Acute dermal toxicity : LD50 (Mouse, male and female): > 3.500 mg/kg
Method: Other
GLP: yes

Skin corrosion/irritation
Product:
Remarks: not tested.
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Components:
2-Butoxy ethanol:
Species: Rabbit
Method: OECD Test Guideline 404
Result: irritating

Ethanediol:
Species: Rabbit
Exposure time: 20 h
Method: BASF test
Result: No skin irritation
GLP: no

Serious eye damage/eye irritation

Product:
Remarks: not tested.

Components:
2-Butoxy ethanol:
Species: rabbit eye
Method: OECD Test Guideline 405
Result: irritating

Ethanediol:
Species: rabbit eye
Exposure time: 24 h
Method: BASF test
Result: non-irritant
GLP: no

Respiratory or skin sensitisation

Product:
Result: May cause sensitization by skin contact.

Components:
Ethanediol:
Test Type: Maximisation Test
Exposure routes: Skin contact
Species: Guinea pig
Method: OECD Test Guideline 406
Result: Does not cause skin sensitisation.
GLP: yes
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Germ cell mutagenicity

Components:
Ethanediol:
Genotoxicity in vitro : Test Type: Ames test
Species: Salmonella typhimurium
Concentration: 33 - 5000 µg/plate
Metabolic activation: with and without
Method: OECD Test Guideline 471
Result: negative
GLP: yes

: Test Type: Ames test

Species: Escherichia coli
Concentration: 33 - 5000 µg/plate
Metabolic activation: with and without
Method: OECD Test Guideline 471
Result: negative
GLP: yes

Genotoxicity in vivo : Test Type: Dominant lethal assay

Species: Rat (male and female)
Strain: Fischer F344
Application Route: oral (feed)
Exposure time: 3 generation
Dose: 40 - 200 - 1000 mg/kg
Method: Other
Result: negative
GLP: no

Germ cell mutagenicity- : It is concluded that the product is not mutagenic based on
Assessment evaluation of several mutagenicity tests.

Carcinogenicity
Components:
Ethanediol:
Carcinogenicity - : Not classifiable as a human carcinogen.
Assessment

Reproductive toxicity
Components:
Ethanediol:
Effects on fertility : Species: Rat
Sex: male and female
Dose: 40 - 200 - 1000
Frequency of Treatment: daily
Fischer F344
Application Route: oral (feed)
Test period: 3 generations
NOAEL: > 1.000 mg/kg,
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F1: > 1.000 mg/kg,

F2: > 1.000 mg/kg,
Method: Other
GLP: no

Effects on foetal : Species: Rat

development Application Route: oral (gavage)
Exposure time: gestation day 6-15
Dose: 150 - 500 - 1000 - 2500 mg/kg
Group: yes
500 mg/kg
1.000 mg/kg
Number of exposures: daily
Method: Other
GLP: yes

Reproductive toxicity - : No reproductive toxicity to be expected.

Assessment No teratogenic effects to be expected.

STOT - single exposure

Components:
Ethanediol:
Assessment: The substance or mixture is not classified as specific target organ toxicant, single
exposure.

STOT - repeated exposure

Components:
Ethanediol:
Target Organs: Kidney
Assessment: May cause damage to organs through prolonged or repeated exposure.

Repeated dose toxicity

Components:
Ethanediol:
Species: Rat, male
NOAEL: 150 mg/kg
Application Route: oral (feed)
Exposure time: 16 w
Number of exposures: daily
Dose: 50 - 150 - 500 - 1000 mg/kg
Group: yes
Method: OECD Test Guideline 408
GLP: yes

Species: Dog, male

NOAEL: ca. 2.200 mg/kg
Application Route: Skin contact
Exposure time: 4 w
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Number of exposures: daily

Dose: 0,5 - 2 - 8 ml/kg
Group: yes
Method: OECD Test Guideline 410
GLP: yes

Aspiration toxicity
Components:
Ethanediol:
No aspiration toxicity classification

SECTION 12: Ecological information

12.1 Toxicity
Product:
Toxicity to fish : Remarks: not tested.

Toxicity to daphnia and other : Remarks: not tested.

aquatic invertebrates

Toxicity to algae : Remarks: not tested.

Components:
2-Butoxy ethanol:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 1.474 mg/l
Exposure time: 96 h

Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 1.550 mg/l
aquatic invertebrates Exposure time: 48 h
Test Type: Immobilization

Toxicity to algae : IC50 (Pseudokirchneriella subcapitata (microalgae)): 911 mg/l

Exposure time: 72 h

Ethanediol:
Toxicity to fish : LC50 (Pimephales promelas (fathead minnow)): 72.860 mg/l
Exposure time: 96 h
Test Type: static test
Analytical monitoring: yes
Method: EPA
GLP: no
Remarks: The details of the toxic effect relate to the nominal
concentration.

Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): > 100 mg/l
aquatic invertebrates Exposure time: 48 h
Test Type: static test
Analytical monitoring: yes
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Method: OECD Test Guideline 202

GLP: yes

Toxicity to algae : EC50 (Pseudokirchneriella subcapitata (green algae)): 6.500 -

13.000 mg/l
End point: Growth rate
Exposure time: 7 d
Test Type: static test
Analytical monitoring: no data available
Method: EPA
GLP: No information available.

Toxicity to bacteria : EC20 (activated sludge, domestic): > 1.995 mg/l

End point: Bacteria toxicity (respiration inhibition)
Exposure time: 0,5 h
Analytical monitoring: no
Method: ISO 8192
GLP: no
Remarks: By analogy with a product of similar composition

Toxicity to fish (Chronic : Chronic Toxicity Value: 2.629 mg/l

toxicity) Exposure time: 30 d
End point: Other
Species: Fish
Method: Other
GLP: no
Remarks: The details of the toxic effect relate to the nominal
concentration.

Toxicity to daphnia and other : NOEC: 8.590 mg/l

aquatic invertebrates Exposure time: 7 d
(Chronic toxicity) End point: Reproduction rate
Species: Ceriodaphnia spec.
Test Type: semi-static test
Analytical monitoring: yes
Method: Other
GLP: No information available.
Remarks: The details of the toxic effect relate to the nominal
concentration.

Toxicity to soil dwelling :

organisms Remarks: The study is not necessary from a scientific
perspective.

Plant toxicity : Remarks: The study is not necessary from a scientific

perspective.

Sediment toxicity : Remarks: The study is not necessary from a scientific

perspective.

Toxicity to terrestrial : Remarks: The study is not necessary from a scientific

organisms perspective.
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12.2 Persistence and degradability

Product:
Biodegradability : Remarks: Not applicable

Physico-chemical : Remarks: not tested.

removability

Components:
2-Butoxy ethanol:
Biodegradability : Test Type: aerobic
Inoculum: activated sludge
Result: Readily biodegradable
Biodegradation: 90,4 %
Exposure time: 28 d

Ethanediol:
Biodegradability : Test Type: aerobic
Inoculum: activated sludge
Concentration: 53 mg/l
Result: Readily biodegradable
Biodegradation: 90 - 100 %
Related to: DOC decrease
Exposure time: 10 d
Method: OECD Test Guideline 301A
GLP: yes

12.3 Bioaccumulative potential

Product:
Bioaccumulation : Remarks: no data available

Components:
Ethanediol:
Bioaccumulation : Remarks: Due to the low logPow bioaccumulation is not
expected

12.4 Mobility in soil

Product:
Distribution among : Remarks: not tested.
environmental compartments

Components:
Ethanediol:
Distribution among : Adsorption/Soil
environmental compartments Medium: water - soil
log Koc: 0
Method: other (calculated)
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12.5 Results of PBT and vPvB assessment

Product:
Assessment : This substance/mixture contains no components considered
to be either persistent, bioaccumulative and toxic (PBT), or
very persistent and very bioaccumulative (vPvB) at levels of
0.1% or higher..

Components:
Ethanediol:
Assessment : This substance is not considered to be persistent,
bioaccumulating and toxic (PBT)..

12.6 Other adverse effects

Product:
Environmental fate and : not tested.
pathways

Additional ecological : The product should not be allowed to enter drains, water
information courses or the soil.

no data available

Components:
Ethanediol:
Environmental fate and : not available
pathways

Additional ecological : Do not allow to enter ground water, waterways or waste water.
information

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product : Dispose of contents/ container to an approved waste disposal
plant.

Contaminated packaging : Empty containers should be taken to local recyclers for

disposal.

SECTION 14: Transport information

Section 14.1. to 14.5.

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ADR not restricted

ADN not restricted
RID not restricted
IATA not restricted
IMDG not restricted

14.6. Special precautions for user

See sections 6 to 8 of this Safety Data Sheet.

14.7. Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code (International
Bulk Chemicals Code)
No transport as bulk according IBC - Code.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or
mixture
Other regulations : European Regulation (EC) No 1272/2008 on classification,
labelling and packaging of substances and mixtures.

15.2 Chemical safety assessment

Chemical Safety Assessments (CSAs) are available for one or more of the component substances
contained in this product.

SECTION 16: Other information

Full text of H-Statements

H302 : Harmful if swallowed.
H312 : Harmful in contact with skin.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H332 : Harmful if inhaled.
H335 : May cause respiratory irritation.
H373 : May cause damage to organs through prolonged or repeated
exposure if swallowed.
H411 : Toxic to aquatic life with long lasting effects.
Full text of other abbreviations
Acute Tox. : Acute toxicity
Aquatic Chronic : Chronic aquatic toxicity
Eye Irrit. : Eye irritation
Skin Irrit. : Skin irritation
STOT RE : Specific target organ toxicity - repeated exposure
STOT SE : Specific target organ toxicity - single exposure
ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways; ADR - European Agreement concerning the International Carriage of Dangerous
Goods by Road; AICS - Australian Inventory of Chemical Substances; ASTM - American Society
for the Testing of Materials; bw - Body weight; CLP - Classification Labelling Packaging
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Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive

Toxicant; DIN - Standard of the German Institute for Standardisation; DSL - Domestic Substances
List (Canada); ECHA - European Chemicals Agency; EC-Number - European Community
number; ECx - Concentration associated with x% response; ELx - Loading rate associated with
x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances
(Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally
Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research
on Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal
inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of
Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO -
International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO -
International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50
- Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test
population (Median Lethal Dose); MARPOL - International Convention for the Prevention of
Pollution from Ships; n.o.s. - Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect
Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect
Loading Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention;
PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of
Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship;
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council
concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID -
Regulations concerning the International Carriage of Dangerous Goods by Rail; SADT - Self-
Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical
Substance Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA - Toxic
Substances Control Act (United States); UN - United Nations; vPvB - Very Persistent and Very
Bioaccumulative
Further information

This information corresponds to the present state of our knowledge and is intended as a general
description of our products and their possible applications. Clariant makes no warranties, express
or implied, as to the information's accuracy, adequacy, sufficiency or freedom from defect and
assumes no liability in connection with any use of this information. Any user of this product is
responsible for determining the suitability of Clariant's products for its particular application.
Nothing included in this information waives any of Clariant's General Terms and Conditions of
Sale, which control unless it agrees otherwise in writing. Any existing intellectual/industrial
property rights must be observed. Due to possible changes in our products and applicable
national and international regulations and laws, the status of our products could change. Material
Safety Data Sheets providing safety precautions, that should be observed when handling or
storing Clariant products, are available upon request and are provided in compliance with
applicable law. You should obtain and review the applicable Material Safety Data Sheet
information before handling any of these products. For additional information, please contact
Clariant.

REG_EU / EN
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 18(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Exposure scenario

Number Title
ES 1 Professional use; Use in oil and gas field drilling and production
operations
PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b - ERC8d
2-Butoxyethanol
ES 2 Industrial use; Industrial use of processing aids in processes and
products, not becoming part of articles
PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC13,
PROC14, PROC15 - ERC4
Ethane-1,2-diol
ES 3 Formulation; Formulation & (re)packing of substances and mixtures
PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC14,
PROC15 - ERC2
2-Butoxyethanol
ES 4 Industrial use; Formulation [mixing] of preparations and/or re-packaging
PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC14,
PROC15 - ERC2
Ethane-1,2-diol
ES 5 Industrial use; Use in functional fluids
PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC9 - ERC7
Ethane-1,2-diol
ES 6 Professional use; Anti-freeze and de-icing products
PROC1, PROC2, PROC8a, PROC8b, PROC11 - ERC8d
Ethane-1,2-diol
ES 7 Professional use; Use in functional fluids
PROC1, PROC2, PROC3, PROC4, PROC8a, PROC9, PROC20 - ERC9a, ERC9b
Ethane-1,2-diol

1. ES 1: Professional use; Use in oil and gas field drilling

and production operations
1.1. Titles of Contributing scenarios (CS)

Environment
CS1: Professional use (Wide dispersive outdoor use of processing aids in ERC8d
open systems)
Workers
CS2: Professional use (Transfer of substance or preparation PROC8b
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CORRTREAT 12286 Page 19(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

(charging/discharging) from/to vessels/large containers at dedicated

facilities)
CS3: Professional use (Transfer of substance or preparation PROC8b
(charging/discharging) from/to vessels/large containers at dedicated
facilities)
CS4: Professional use (Use in closed batch process (synthesis or PROC3
formulation))
CS5: Professional use (Use in batch and other process (synthesis) where PROC4
opportunity for exposure arises)
CS6: Professional use (Use in batch and other process (synthesis) where PROC4
opportunity for exposure arises)
CS7: Professional use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS8: Professional use (Use in closed batch process (synthesis or PROC3
formulation))
CS9: Professional use (Use in closed batch process (synthesis or PROC3
formulation))
CS10: Professional use (Use in closed process, no likelihood of exposure) PROC1
CS11: Professional use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS12: Professional use (Use in batch and other process (synthesis) where PROC4
opportunity for exposure arises)
CS13: Professional use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS14: Professional use (Use in closed process, no likelihood of exposure, Use PROC1, PROC2
in closed, continuous process with occasional controlled exposure)

1.2. ES 1 Conditions of use affecting exposure

1.2.1 ES 1 - CS 1: Control of environmental exposure: Professional use (Wide
dispersive outdoor use of processing aids in open systems) (ERC8d)

Product characteristics
Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure

Amount used
Annual amount per site : 50 tonnes/year
Daily amount per site : 3100 kg/day

Frequency and duration of use

Continuous exposure : 16 days per year, Batch process

Technical conditions and measures / Organizational measures

Water : No wastewater treatment required.
Soil : Soil emission controls are not applicable as there is no direct
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CORRTREAT 12286 Page 20(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

release to soil.
Remarks : Prevent environmental discharge consistent with regulatory
requirements.
Air emission controls are not appliable as there is no direct
release to air.

Waste management measures

Waste treatment : Incineration
Disposal methods : Dispose of waste product or used containers according to
local regulations. (Effectiveness (of a measure): 99,98 %)
Conditions and measures related to external recovery of waste
Recovery Methods : Not applicable

1.2.2 ES 1 - CS 2: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
dedicated facilities) (PROC8b)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Bulk transfers from tote tanks and supply vessels

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 21(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

characterisation.

Type of Application (Use) : Bulk transfers from tote tanks and supply vessels
Organisational measures to : Ensure operation is undertaken outdoors.
prevent /limit releases, dispersion
and exposure
Personal protective measures : Use suitable eye protection.

1.2.3 ES 1 - CS 3: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
dedicated facilities) (PROC8b)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Filling of equipment from drums or containers

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Filling of equipment from drums or containers

Organisational measures to : Ensure operation is undertaken outdoors.
prevent /limit releases, dispersion
and exposure
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 22(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Personal protective measures : Use suitable eye protection.

1.2.4 ES 1 - CS 4: Control of worker exposure: Professional use (Use in closed batch

process (synthesis or formulation)) (PROC3)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Drilling mud (re-)formulation

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Drilling mud (re-)formulation

Personal protective measures : Use suitable eye protection.

1.2.5 ES 1 - CS 5: Control of worker exposure: Professional use (Use in batch and

other process (synthesis) where opportunity for exposure arises) (PROC4)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Drill floor operations
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 23(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Drill floor operations

Organisational measures to : Ensure operation is undertaken outdoors.
prevent /limit releases, dispersion
and exposure
Personal protective measures : Use suitable eye protection.

1.2.6 ES 1 - CS 6: Control of worker exposure: Professional use (Use in batch and

other process (synthesis) where opportunity for exposure arises) (PROC4)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Operation of solids filtering equipment
With potential for aerosol generation
Elevated temperature

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 24(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Operation of solids filtering equipment

With potential for aerosol generation
Elevated temperature
Technical conditions and : Provide extract ventilation to points where emissions occur.
measures
Effectiveness (of a measure) : >= 90 %
Personal protective measures : Use suitable eye protection.

1.2.7 ES 1 - CS 7: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
non dedicated facilities) (PROC8a)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Cleaning of solids filtering equipment

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.
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according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 25(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Frequency and duration of use

Exposure duration : <4h

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Cleaning of solids filtering equipment

Organisational measures to : Avoid carrying out activities involving exposure for more than
prevent /limit releases, dispersion 4 hours per day.
and exposure
Technical conditions and : Provide a good standard of controlled ventilation (10 to 15 air
measures changes per hour).
Personal protective measures : Use suitable eye protection.

1.2.8 ES 1 - CS 8: Control of worker exposure: Professional use (Use in closed batch

process (synthesis or formulation)) (PROC3)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Treatment and disposal of filtered solids

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

SAFETY DATA SHEET
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CORRTREAT 12286 Page 26(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Treatment and disposal of filtered solids

Personal protective measures : Use suitable eye protection.

1.2.9 ES 1 - CS 9: Control of worker exposure: Professional use (Use in closed batch

process (synthesis or formulation)) (PROC3)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Process sampling

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 27(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

hand contact with substance likely. Clean up

contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Process sampling

Personal protective measures : Use suitable eye protection.

1.2.10 ES 1 - CS 10: Control of worker exposure: Professional use (Use in closed

process, no likelihood of exposure) (PROC1)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Processing aid
Automated task

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

1.2.11 ES 1 - CS 11: Control of worker exposure: Professional use (Transfer of

SAFETY DATA SHEET
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CORRTREAT 12286 Page 28(82)

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substance or preparation (charging/discharging) from/to vessels/large containers at

non dedicated facilities) (PROC8a)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Processing aid
Manual

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 4h

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Processing aid

Manual
Organisational measures to : Avoid carrying out activities involving exposure for more than
prevent /limit releases, dispersion 4 hours per day.
and exposure
Technical conditions and : Provide a good standard of controlled ventilation (10 to 15 air
measures changes per hour).
Personal protective measures : Use suitable eye protection.

1.2.12 ES 1 - CS 12: Control of worker exposure: Professional use (Use in batch and
other process (synthesis) where opportunity for exposure arises) (PROC4)

Remarks : Oil field well drilling operations (including drilling muds and
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well cleaning) including material transfers, on-site formulation,

well head operations, shaker room activities and related
maintenance.
Scale squeeze operations

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 12 h

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Organisational measures to : Ensure operation is undertaken outdoors.

prevent /limit releases, dispersion
and exposure
Personal protective measures : Use suitable eye protection.

1.2.13 ES 1 - CS 13: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
non dedicated facilities) (PROC8a)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
Equipment cleaning and maintenance

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article
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CORRTREAT 12286 Page 30(82)

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Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 4h

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : Equipment cleaning and maintenance

Organisational measures to : Avoid carrying out activities involving exposure for more than
prevent /limit releases, dispersion 4 hours per day.
and exposure
Technical conditions and : Provide a good standard of controlled ventilation (10 to 15 air
measures changes per hour).
Personal protective measures : Use suitable eye protection.

1.2.14 ES 1 - CS 14: Control of worker exposure: Professional use (Use in closed

process, no likelihood of exposure, Use in closed, continuous process with
occasional controlled exposure) (PROC1, PROC2)

Remarks : Oil field well drilling operations (including drilling muds and
well cleaning) including material transfers, on-site formulation,
well head operations, shaker room activities and related
maintenance.
General exposures (closed systems)
Storage
With sample collection

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid, vapour pressure < 0.5 kPa at Standard Temperature
and Pressure
SAFETY DATA SHEET
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CORRTREAT 12286 Page 31(82)

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Remarks : Assumes use at not more than 20°C above ambient

temperature.

Frequency and duration of use

Exposure duration : 12 h
Remarks : Batch process

Other operational conditions affecting workers exposure

Outdoor / Indoor : Outdoor

Risk Management Measures

Organisational measures to : Assumes a good basic standard of occupational hygiene is
prevent /limit releases, dispersion implemented
and exposure Supervision in place to check that the RMMs in place are
being used correctly and OCs followed.
Avoid direct skin contact with product. Identify potential areas
for indirect skin contact. Wear gloves (tested to EN374) if
hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Note : Risk management measures are based on qualitative risk
characterisation.

Type of Application (Use) : General exposures (closed systems)

Storage
With sample collection
Personal protective measures : Use suitable eye protection.

1.3. ES 1 Exposure estimation and reference to its source

1.3.1 ES 1 - CS 1: Environmental release and exposure: Professional use (Wide
dispersive outdoor use of processing aids in open systems) (ERC8d)

Release route Release rate Release estimation method

Air 0 kg/day CHARM model
Water 3100 kg/day CHARM model
Soil 0 kg/day CHARM model

Protection target Exposure estimation and reference to its source RCR

(based on CHARM model)
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Sewage treatment plant. Not applicable

Freshwater Not applicable
Freshwater sediment Not applicable
Marine water Not applicable
Marine sediment < 0,0000006 mg/kg dry weight < 0,01
Soil Not applicable, Risk from environmental exposure is
driven by soil.

1.3.2 ES 1 - CS 2: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities) (PROC8b)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 9,1 ppm (ECETOC TRA worker V3, Bulk transfers from 0,455
tote tanks and supply vessels)
Dermal 17,823 mg/kg bw/day (ECETOC TRA worker V3, Bulk 0,238
transfers from tote tanks and supply vessels)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.3 ES 1 - CS 3: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities) (PROC8b)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 9,1 ppm (ECETOC TRA worker V3, Filling of equipment 0,455
from drums or containers)
Dermal 17,823 mg/kg bw/day (ECETOC TRA worker V3, Filling 0,238
of equipment from drums or containers)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.4 ES 1 - CS 4: Worker exposure: Professional use (Use in closed batch process

(synthesis or formulation)) (PROC3)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 3,9 ppm (ECETOC TRA worker V3, Drilling mud (re- 0,195
)formulation)
Dermal 0,897 mg/kg bw/day (ECETOC TRA worker V3, Drilling 0,012
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 33(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

mud (re-)formulation)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.5 ES 1 - CS 5: Worker exposure: Professional use (Use in batch and other

process (synthesis) where opportunity for exposure arises) (PROC4)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 9,1 ppm (ECETOC TRA worker V3, Drill floor operations) 0,455
Dermal 8,918 mg/kg bw/day (ECETOC TRA worker V3, Drill floor 0,119
operations)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.6 ES 1 - CS 6: Worker exposure: Professional use (Use in batch and other

process (synthesis) where opportunity for exposure arises) (PROC4)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 6,5 ppm (ECETOC TRA worker V3, Operation of solids 0,325
filtering equipment, With potential for aerosol generation,
Elevated temperature)
Dermal 1,784 mg/kg bw/day (ECETOC TRA worker V3, 0,024
Operation of solids filtering equipment, With potential for
aerosol generation, Elevated temperature)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.7 ES 1 - CS 7: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 4,5 ppm (ECETOC TRA worker V3, Cleaning of solids 0,225
filtering equipment)
Dermal 13,71 mg/kg bw/day (ECETOC TRA worker V3, Cleaning 0,183
of solids filtering equipment)
Available hazard data do not enable the derivation
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 34(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

of a DNEL for dermal irritant effects., Available

hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.8 ES 1 - CS 8: Worker exposure: Professional use (Use in closed batch process

(synthesis or formulation)) (PROC3)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 3,9 ppm (ECETOC TRA worker V3, Treatment and 0,195
disposal of filtered solids)
Dermal 0,897 mg/kg bw/day (ECETOC TRA worker V3, 0,012
Treatment and disposal of filtered solids)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.9 ES 1 - CS 9: Worker exposure: Professional use (Use in closed batch process

(synthesis or formulation)) (PROC3)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 3,9 ppm (ECETOC TRA worker V3, Process sampling) 0,195
Dermal 0,897 mg/kg bw/day (ECETOC TRA worker V3, Process 0,012
sampling)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.10 ES 1 - CS 10: Worker exposure: Professional use (Use in closed process, no

likelihood of exposure) (PROC1)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 0,013 ppm (ECETOC TRA worker V3, Processing aid, < 0,001
Automated task)
Dermal 0,039 mg/kg bw/day (ECETOC TRA worker V3, < 0,001
Processing aid, Automated task)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 35(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

1.3.11 ES 1 - CS 11: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 4,5 ppm (ECETOC TRA worker V3, Processing aid, 0,225
Manual)
Dermal 13,71 mg/kg bw/day (ECETOC TRA worker V3, 0,183
Processing aid, Manual)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.12 ES 1 - CS 12: Worker exposure: Professional use (Use in batch and other
process (synthesis) where opportunity for exposure arises) (PROC4)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 9,1 ppm (ECETOC TRA worker V3, Scale squeeze 0,455
operations)
Dermal 8,918 mg/kg bw/day (ECETOC TRA worker V3, Scale 0,119
squeeze operations)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.13 ES 1 - CS 13: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 4,5 ppm (ECETOC TRA worker V3, Equipment cleaning 0,225
and maintenance)
Dermal 13,71 mg/kg bw/day (ECETOC TRA worker V3, 0,183
Equipment cleaning and maintenance)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.3.14 ES 1 - CS 14: Worker exposure: Professional use (Use in closed process, no

likelihood of exposure, Use in closed, continuous process with occasional controlled
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 36(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

exposure) (PROC1, PROC2)

Route of exposure and type Exposure estimate RCR

of effects
inhalative 6,5 ppm (ECETOC TRA worker V3, General exposures 0,325
(closed systems), Storage, With sample collection)
Dermal 1,781 mg/kg bw/day (ECETOC TRA worker V3, General 0,024
exposures (closed systems), Storage, With sample
collection)
Available hazard data do not enable the derivation
of a DNEL for dermal irritant effects., Available
hazard data do not enable the derivation of a DNEL
for eye irritant effects.

1.4. ES 1 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario
ECHA guidance for downstream users
Section 2
Environment

2. ES 2: Industrial use; Industrial use of processing aids in

processes and products, not becoming part of articles
2.1. Titles of Contributing scenarios (CS)

Environment
CS1: Industrial use (Industrial use of processing aids in processes and ERC4
products, not becoming part of articles)
Workers
CS2: Industrial use (Use in closed process, no likelihood of exposure) PROC1
CS3: Industrial use (Use in closed, continuous process with occasional PROC2
controlled exposure)
CS4: Industrial use (Use in closed batch process (synthesis or formulation), PROC3, PROC4
Use in batch and other process (synthesis) where opportunity for
exposure arises)
CS5: Industrial use (Mixing or blending in batch processes for formulation of PROC5
preparations and articles (multistage and/or significant contact))
CS6: Industrial use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS7: Industrial use (Transfer of substance or preparation PROC8b, PROC9
(charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers
(dedicated filling line, including weighing))
CS8: Industrial use (Treatment of articles by dipping and pouring) PROC13
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 37(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

CS9: Industrial use (Production of preparations or articles by tabletting, PROC14

compression, extrusion, pelettisation)
CS10: Industrial use (Use as laboratory reagent) PROC15

2.2. ES 2 Conditions of use affecting exposure

2.2.1 ES 2 - CS 1: Control of environmental exposure: Industrial use (Industrial use
of processing aids in processes and products, not becoming part of articles) (ERC4)

Remarks : As no environmental hazard was identified no environmental-

related exposure assessment and risk characterization was
performed.

2.2.2 ES 2 - CS 2: Control of worker exposure: Industrial use (Use in closed process,

no likelihood of exposure) (PROC1)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed process, no likelihood of exposure
measures Sample via a closed loop or other system to avoid exposure.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.3 ES 2 - CS 3: Control of worker exposure: Industrial use (Use in closed,

continuous process with occasional controlled exposure) (PROC2)
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 38(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : Use in closed, continuous process with occasional controlled
exposure
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.4 ES 2 - CS 4: Control of worker exposure: Industrial use (Use in closed batch

process (synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
Remarks : Use in closed batch process (synthesis or formulation)
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Remarks : Use in batch and other process (synthesis) where opportunity
for exposure arises

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 39(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Risk Management Measures

Technical conditions and : Use in closed batch process (synthesis or formulation)
measures

Note : Use in batch and other process (synthesis) where opportunity

for exposure arises
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.5 ES 2 - CS 5: Control of worker exposure: Industrial use (Mixing or blending in

batch processes for formulation of preparations and articles (multistage and/or
significant contact)) (PROC5)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : Dermal
Personal protective measures : Wear chemically resistant gloves (tested to EN374) in
combination with specific activity training.
Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.6 ES 2 - CS 6: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at non
dedicated facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 40(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Both hands
Covers skin contact area up to : 960 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : inhalative
Technical conditions and : Local exhaust ventilation
measures
Effectiveness (of a measure) : 90 %
Personal protective measures : If technical measures not practical:
Wear respiratory protection.
Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.7 ES 2 - CS 7: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 41(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Additional good practice advice : Wear solely goggles.

2.2.8 ES 2 - CS 8: Control of worker exposure: Industrial use (Treatment of articles

by dipping and pouring) (PROC13)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : Dermal
Personal protective measures : Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training.
Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.9 ES 2 - CS 9: Control of worker exposure: Industrial use (Production of

preparations or articles by tabletting, compression, extrusion, pelettisation) (PROC14)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 42(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.2.10 ES 2 - CS 10: Control of worker exposure: Industrial use (Use as laboratory

reagent) (PROC15)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Amount used
Storage : < 1 kg, < 1 l

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 240 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : Use as laboratory reagent
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

2.3. ES 2 Exposure estimation and reference to its source

2.3.2 ES 2 - CS 2: Worker exposure: Industrial use (Use in closed process, no

likelihood of exposure) (PROC1)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,03 mg/m³ (ECETOC TRA v2.0 worker) 0,0007
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,003
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according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 43(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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systemic
combined routes ECETOC TRA v2.0 worker 0,004

2.3.3 ES 2 - CS 3: Worker exposure: Industrial use (Use in closed, continuous

process with occasional controlled exposure) (PROC2)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
systemic
combined routes ECETOC TRA v2.0 worker 0,08

2.3.4 ES 2 - CS 4: Worker exposure: Industrial use (Use in closed batch process

(synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 7,76 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,22
- local and systemic batch process (synthesis or formulation))
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed batch process (synthesis or formulation))
combined routes ECETOC TRA v2.0 worker, Use in closed batch process 0,23
(synthesis or formulation)
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Use in batch 0,37
- local and systemic and other process (synthesis) where opportunity for
exposure arises)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,06
systemic batch and other process (synthesis) where opportunity for
exposure arises)
combined routes ECETOC TRA v2.0 worker, Use in batch and other 0,43
process (synthesis) where opportunity for exposure
arises

2.3.5 ES 2 - CS 5: Worker exposure: Industrial use (Mixing or blending in batch

processes for formulation of preparations and articles (multistage and/or significant
contact)) (PROC5)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
systemic
combined routes ECETOC TRA v2.0 worker 0,38
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according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 44(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

2.3.6 ES 2 - CS 6: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,13
systemic
combined routes ECETOC TRA v2.0 worker 0,20

2.3.7 ES 2 - CS 7: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation (charging/discharging)
from/to vessels/large containers at dedicated facilities)
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation (charging/discharging) from/to vessels/large
containers at dedicated facilities
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation into small containers (dedicated
filling line, including weighing))
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation into small containers
(dedicated filling line, including weighing))
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation into small containers (dedicated filling line,
including weighing)

2.3.8 ES 2 - CS 8: Worker exposure: Industrial use (Treatment of articles by dipping

and pouring) (PROC13)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 25,87 mg/m³ (ECETOC TRA v2.0 worker) 0,74
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
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according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 45(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

systemic
combined routes ECETOC TRA v2.0 worker 0,75

2.3.9 ES 2 - CS 9: Worker exposure: Industrial use (Production of preparations or

articles by tabletting, compression, extrusion, pelettisation) (PROC14)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 3,43 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,03
systemic
combined routes ECETOC TRA v2.0 worker 0,40

2.3.10 ES 2 - CS 10: Worker exposure: Industrial use (Use as laboratory reagent)

(PROC15)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,003
systemic
combined routes ECETOC TRA v2.0 worker 0,37

2.4. ES 2 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario
ECHA guidance for downstream users
Section 2

3. ES 3: Formulation; Formulation & (re)packing of

substances and mixtures
3.1. Titles of Contributing scenarios (CS)

Environment
CS1: Formulation (Formulation of preparations) ERC2
Workers
CS2: Formulation (Use in closed process, no likelihood of exposure) PROC1
CS3: Formulation (Use in closed, continuous process with occasional PROC2
controlled exposure)
CS4: Formulation (Use in closed batch process (synthesis or formulation)) PROC3
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 46(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

CS5: Formulation (Use in batch and other process (synthesis) where PROC4
opportunity for exposure arises)
CS6: Formulation (Mixing or blending in batch processes for formulation of PROC5
preparations and articles (multistage and/or significant contact))
CS7: Formulation (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS8: Formulation (Transfer of substance or preparation PROC8b
(charging/discharging) from/to vessels/large containers at dedicated
facilities)
CS9: Formulation (Transfer of substance or preparation into small containers PROC9
(dedicated filling line, including weighing))
CS10: Formulation (Use as laboratory reagent) PROC15

3.2. ES 3 Conditions of use affecting exposure

3.2.1 ES 3 - CS 1: Control of environmental exposure: Formulation (Formulation of
preparations) (ERC2)

Amount used
Annual amount per site : 25000 tonnes/year
Daily amount per site : 83000 kg/day

Frequency and duration of use

Continuous exposure : 300 days per year

Environment factors not influenced by risk management

Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Technical conditions and measures / Organizational measures

Remarks : No air emission controls required; required removal efficiency
is 0%.
Risk from environmental exposure is driven by freshwater.
Prevent discharge of undissolved substance to or recover
from onsite wastewater.
If discharging to municipal sewage treatment plant, no onsite
wastewater treatment required.
Common practices vary across sites thus conservative
process release estimates used.
Site should have a spill plan to ensure that adequate
safeguards are in place to minimize the impact of episodic
releases.
A leak prevention plan is needed to prevent low level continual
releases.
Bund storage facilities to prevent soil and water pollution in
the event of spillage.

Conditions and measures related to sewage treatment plant

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CORRTREAT 12286 Page 47(82)

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Flow rate of sewage treatment : 2.000 m3/d

plant effluent
Effectiveness (of a measure) : 87,4 %
Sludge Treatment : No application of sewage sludge to soil, Sewage sludge
should be incinerated, contained or reclaimed.

Waste management measures

Waste treatment : External treatment and disposal of waste should comply with
applicable local and/or national regulations.
Conditions and measures related to external recovery of waste
Recovery Methods : External recovery and recycling of waste should comply with
applicable local and/or national regulations.

3.2.2 ES 3 - CS 2: Control of worker exposure: Formulation (Use in closed process,

no likelihood of exposure) (PROC1)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.
Technical conditions and : Handle substance within a closed system.
measures

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.3 ES 3 - CS 3: Control of worker exposure: Formulation (Use in closed,

continuous process with occasional controlled exposure) (PROC2)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article
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CORRTREAT 12286 Page 48(82)

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Version : 4 - 0 / EU Date of printing : 15.09.2016

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.
Technical conditions and : Handle substance within a closed system.
measures

Type of Application (Use) : Bulk product storage

Technical conditions and : Transfer via enclosed lines.
measures Store substance within a closed system.
Avoid dip sampling.

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.4 ES 3 - CS 4: Control of worker exposure: Formulation (Use in closed batch

process (synthesis or formulation)) (PROC3)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
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CORRTREAT 12286 Page 49(82)

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Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.
Technical conditions and : Handle substance within a closed system.
measures

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.5 ES 3 - CS 5: Control of worker exposure: Formulation (Use in batch and other

process (synthesis) where opportunity for exposure arises) (PROC4)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.
Technical conditions and : Handle substance within a closed system.
measures

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.6 ES 3 - CS 6: Control of worker exposure: Formulation (Mixing or blending in

batch processes for formulation of preparations and articles (multistage and/or
significant contact)) (PROC5)
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CORRTREAT 12286 Page 50(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.

Type of Application (Use) : Mixing operations (open systems)

Technical conditions and : Provide extract ventilation to points where emissions occur.
measures

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.7 ES 3 - CS 7: Control of worker exposure: Formulation (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

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CORRTREAT 12286 Page 51(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Type of Application (Use) : General exposures

Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.

Type of Application (Use) : Mixing operations (open systems)

Technical conditions and : Provide extract ventilation to points where emissions occur.
measures

Type of Application (Use) : Transfer from/pouring from containers

Technical conditions and : Use drum pumps.
measures

Type of Application (Use) : Equipment cleaning and maintenance

Technical conditions and : Drain down and flush system prior to equipment break-in or
measures maintenance.
Provide a good standard of controlled ventilation (10 to 15 air
changes per hour).

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.8 ES 3 - CS 8: Control of worker exposure: Formulation (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities) (PROC8b)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
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CORRTREAT 12286 Page 52(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

to prevent / minimise exposures and to report any skin

problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.
Technical conditions and : Handle substance within a closed system.
measures

Type of Application (Use) : Mixing operations (open systems)

Technical conditions and : Provide extract ventilation to points where emissions occur.
measures

Type of Application (Use) : Bulk transfers

Technical conditions and : Clear transfer lines prior to de-coupling.
measures

Type of Application (Use) : Transfer from/pouring from containers

Technical conditions and : Use drum pumps.
measures

Type of Application (Use) : Drum/batch transfers

Technical conditions and : Avoid spillage when withdrawing pump.
measures

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.9 ES 3 - CS 9: Control of worker exposure: Formulation (Transfer of substance or

preparation into small containers (dedicated filling line, including weighing)) (PROC9)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
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CORRTREAT 12286 Page 53(82)

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on hands.
Technical conditions and : Fill containers/cans at dedicated fill points supplied with local
measures extract ventilation.
Put lids on containers immediately after use.

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.2.10 ES 3 - CS 10: Control of worker exposure: Formulation (Use as laboratory

reagent) (PROC15)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Liquid

Vapour pressure : < 5 hPa
Remarks : Assumes use at not more than 20°C above ambient
temperature.

Frequency and duration of use

Exposure duration : 8h
Remarks : Continuous process

Risk Management Measures

Type of Application (Use) : General exposures
Organisational measures to : Avoid direct skin contact with product. Identify potential areas
prevent /limit releases, dispersion for indirect skin contact. Wear gloves (tested to EN374) if
and exposure hand contact with substance likely. Clean up
contamination/spills as soon as they occur. Wash off any skin
contamination immediately. Provide basic employee training
to prevent / minimise exposures and to report any skin
problems that may develop.
Avoid direct eye contact with product, also via contamination
on hands.

Exposure routes : Dermal

Personal protective measures : Wear suitable gloves (tested to EN374) and eye protection.

3.3. ES 3 Exposure estimation and reference to its source

3.3.1 ES 3 - CS 1: Environmental release and exposure: Formulation (Formulation of
preparations) (ERC2)

Release route Release rate Release estimation method

Air 83 kg/d ECETOC TRA worker V3, (Initial
release prior to RMM)
Water 41,5 kg/day ECETOC TRA worker V3, (Initial
release prior to RMM)
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CORRTREAT 12286 Page 54(82)

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Soil 0,83 kg/day ECETOC TRA worker V3, (Initial

release prior to RMM)

Protection target Exposure estimation and reference to its source RCR

(based on ECETOC TRA worker V3)
Sewage treatment plant. 20,8 mg/L 0,044924
Freshwater 0,264 mg/L 0,0301
Freshwater sediment 1,03 mg/kg dry weight 0,0297
Marine water 0,0266 mg/L 0,030227
Marine sediment 0,022 mg/kg dry weight 0,006432
Soil 0,0485 mg/kg dry weight 0,020815
Air 0,0191 mg/m³

3.3.2 ES 3 - CS 2: Worker exposure: Formulation (Use in closed process, no

likelihood of exposure) (PROC1)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,01 ppm (ESIG GES tool, worker) < 0,01
- systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ESIG GES tool, worker) < 0,01
systemic

3.3.3 ES 3 - CS 3: Worker exposure: Formulation (Use in closed, continuous process

with occasional controlled exposure) (PROC2)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 1 ppm (ESIG GES tool, worker) 0,1
- systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ESIG GES tool, worker) < 0,01
systemic

3.3.4 ES 3 - CS 4: Worker exposure: Formulation (Use in closed batch process

(synthesis or formulation)) (PROC3)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 3 ppm (ESIG GES tool, worker) 0,2
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ESIG GES tool, worker) < 0,01
systemic

3.3.5 ES 3 - CS 5: Worker exposure: Formulation (Use in batch and other process

(synthesis) where opportunity for exposure arises) (PROC4)
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CORRTREAT 12286 Page 55(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 5 ppm (ESIG GES tool, worker) 0,3
- systemic
Worker - dermal, long-term - 6,86 mg/kg bw/day (ESIG GES tool, worker) 0,1
systemic

3.3.6 ES 3 - CS 6: Worker exposure: Formulation (Mixing or blending in batch

processes for formulation of preparations and articles (multistage and/or significant
contact)) (PROC5)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 5 ppm (ESIG GES tool, worker) 0,3
- systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ESIG GES tool, worker) 0,2
systemic

3.3.7 ES 3 - CS 7: Worker exposure: Formulation (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 10 ppm (ESIG GES tool, worker) 0,5
- systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ESIG GES tool, worker) 0,2
systemic

3.3.8 ES 3 - CS 8: Worker exposure: Formulation (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities) (PROC8b)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 5 ppm (ESIG GES tool, worker) 0,3
- systemic
Worker - dermal, long-term - 6,86 mg/kg bw/day (ESIG GES tool, worker) 0,1
systemic

3.3.9 ES 3 - CS 9: Worker exposure: Formulation (Transfer of substance or

preparation into small containers (dedicated filling line, including weighing)) (PROC9)

Route of exposure and type Exposure estimate RCR

of effects
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according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 56(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Worker - inhalative, long-term 5 ppm (ESIG GES tool, worker) 0,3

- systemic
Worker - dermal, long-term - 6,86 mg/kg bw/day (ESIG GES tool, worker) 0,1
systemic

3.3.10 ES 3 - CS 10: Worker exposure: Formulation (Use as laboratory reagent)

(PROC15)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 5 ppm (ESIG GES tool, worker) 0,3
- systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ESIG GES tool, worker) < 0,01
systemic

3.4. ES 3 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario
ECHA guidance for downstream users
Section 2
Environment
Guidance is based on assumed operating conditions which may not be applicable to all sites;
thus, scaling may be necessary to define appropriate site-specific risk management measures.
Required removal efficiency for wastewater can be achieved using onsite/offsite technologies,
either alone or in combination.
Required removal efficiency for air can be achieved using on-site technologies, either alone or in
combination.
Further details on scaling and control technologies are provided in SpERC factsheet
(http://cefic.org/en/reach-for-industries-libraries.html).
Health
Estimated workplace exposures are not expected to exceed DNELs when the identified risk
management measures are adopted.
Where other risk management measures/operational conditions are adopted, then users should
ensure that risks are managed to at least equivalent levels.

4. ES 4: Industrial use; Formulation [mixing] of

preparations and/or re-packaging
4.1. Titles of Contributing scenarios (CS)

Environment
CS1: Industrial use (Formulation of preparations) ERC2
Workers
CS2: Industrial use (Use in closed process, no likelihood of exposure) PROC1
CS3: Industrial use (Use in closed, continuous process with occasional PROC2
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CORRTREAT 12286 Page 57(82)

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controlled exposure)
CS4: Industrial use (Use in closed batch process (synthesis or formulation), PROC3, PROC4
Use in batch and other process (synthesis) where opportunity for
exposure arises)
CS5: Industrial use (Mixing or blending in batch processes for formulation of PROC5
preparations and articles (multistage and/or significant contact))
CS6: Industrial use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS7: Industrial use (Transfer of substance or preparation PROC8b, PROC9
(charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers
(dedicated filling line, including weighing))
CS8: Industrial use (Production of preparations or articles by tabletting, PROC14
compression, extrusion, pelettisation)
CS9: Industrial use (Use as laboratory reagent) PROC15

4.2. ES 4 Conditions of use affecting exposure

4.2.1 ES 4 - CS 1: Control of environmental exposure: Industrial use (Formulation of
preparations) (ERC2)

Remarks : As no environmental hazard was identified no environmental-

related exposure assessment and risk characterization was
performed.

4.2.2 ES 4 - CS 2: Control of worker exposure: Industrial use (Use in closed process,

no likelihood of exposure) (PROC1)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
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CORRTREAT 12286 Page 58(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed process, no likelihood of exposure
measures Sample via a closed loop or other system to avoid exposure.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.3 ES 4 - CS 3: Control of worker exposure: Industrial use (Use in closed,

continuous process with occasional controlled exposure) (PROC2)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : Use in closed, continuous process with occasional controlled
exposure
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.4 ES 4 - CS 4: Control of worker exposure: Industrial use (Use in closed batch

process (synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

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CORRTREAT 12286 Page 59(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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Exposure duration : <= 480 min

Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
Remarks : Use in closed batch process (synthesis or formulation)
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Remarks : Use in batch and other process (synthesis) where opportunity
for exposure arises

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed batch process (synthesis or formulation)
measures

Note : Use in batch and other process (synthesis) where opportunity

for exposure arises
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.5 ES 4 - CS 5: Control of worker exposure: Industrial use (Mixing or blending in

batch processes for formulation of preparations and articles (multistage and/or
significant contact)) (PROC5)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : Dermal
Personal protective measures : Wear chemically resistant gloves (tested to EN374) in
combination with specific activity training.
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CORRTREAT 12286 Page 60(82)

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Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.6 ES 4 - CS 6: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at non
dedicated facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Both hands
Covers skin contact area up to : 960 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : inhalative
Technical conditions and : Local exhaust ventilation
measures
Effectiveness (of a measure) : 90 %
Personal protective measures : If technical measures not practical:
Wear respiratory protection.
Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.7 ES 4 - CS 7: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 61(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Exposure duration : <= 480 min

Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.8 ES 4 - CS 8: Control of worker exposure: Industrial use (Production of

preparations or articles by tabletting, compression, extrusion, pelettisation) (PROC14)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.2.9 ES 4 - CS 9: Control of worker exposure: Industrial use (Use as laboratory

reagent) (PROC15)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 62(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Amount used
Storage : < 1 kg, < 1 l

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 240 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : Use as laboratory reagent
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

4.3. ES 4 Exposure estimation and reference to its source

4.3.2 ES 4 - CS 2: Worker exposure: Industrial use (Use in closed process, no

likelihood of exposure) (PROC1)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,03 mg/m³ (ECETOC TRA v2.0 worker) 0,0007
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,003
systemic
combined routes ECETOC TRA v2.0 worker 0,004

4.3.3 ES 4 - CS 3: Worker exposure: Industrial use (Use in closed, continuous

process with occasional controlled exposure) (PROC2)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
systemic
combined routes ECETOC TRA v2.0 worker 0,08
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 63(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

4.3.4 ES 4 - CS 4: Worker exposure: Industrial use (Use in closed batch process

(synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 7,76 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,22
- local and systemic batch process (synthesis or formulation))
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed batch process (synthesis or formulation))
combined routes ECETOC TRA v2.0 worker, Use in closed batch process 0,23
(synthesis or formulation)
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Use in batch 0,37
- local and systemic and other process (synthesis) where opportunity for
exposure arises)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,06
systemic batch and other process (synthesis) where opportunity for
exposure arises)
combined routes ECETOC TRA v2.0 worker, Use in batch and other 0,43
process (synthesis) where opportunity for exposure
arises

4.3.5 ES 4 - CS 5: Worker exposure: Industrial use (Mixing or blending in batch

processes for formulation of preparations and articles (multistage and/or significant
contact)) (PROC5)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
systemic
combined routes ECETOC TRA v2.0 worker 0,38

4.3.6 ES 4 - CS 6: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,13
systemic
combined routes ECETOC TRA v2.0 worker 0,20
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 64(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

4.3.7 ES 4 - CS 7: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation (charging/discharging)
from/to vessels/large containers at dedicated facilities)
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation (charging/discharging) from/to vessels/large
containers at dedicated facilities
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation into small containers (dedicated
filling line, including weighing))
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation into small containers
(dedicated filling line, including weighing))
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation into small containers (dedicated filling line,
including weighing)

4.3.8 ES 4 - CS 8: Worker exposure: Industrial use (Production of preparations or

articles by tabletting, compression, extrusion, pelettisation) (PROC14)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 3,43 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,03
systemic
combined routes ECETOC TRA v2.0 worker 0,40

4.3.9 ES 4 - CS 9: Worker exposure: Industrial use (Use as laboratory reagent)

(PROC15)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,003
systemic
combined routes ECETOC TRA v2.0 worker 0,37
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 65(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

4.4. ES 4 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario
ECHA guidance for downstream users
Section 2

5. ES 5: Industrial use; Use in functional fluids

5.1. Titles of Contributing scenarios (CS)

Environment
CS1: Industrial use (Industrial use of substances in closed systems) ERC7
Workers
CS2: Industrial use (Use in closed process, no likelihood of exposure) PROC1
CS3: Industrial use (Use in closed, continuous process with occasional PROC2
controlled exposure)
CS4: Industrial use (Use in closed batch process (synthesis or formulation), PROC3, PROC4
Use in batch and other process (synthesis) where opportunity for
exposure arises)
CS5: Industrial use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS6: Industrial use (Transfer of substance or preparation PROC8b, PROC9
(charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers
(dedicated filling line, including weighing))

5.2. ES 5 Conditions of use affecting exposure

5.2.1 ES 5 - CS 1: Control of environmental exposure: Industrial use (Industrial use
of substances in closed systems) (ERC7)

Remarks : As no environmental hazard was identified no environmental-

related exposure assessment and risk characterization was
performed.

5.2.2 ES 5 - CS 2: Control of worker exposure: Industrial use (Use in closed process,

no likelihood of exposure) (PROC1)
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 66(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed process, no likelihood of exposure
measures Sample via a closed loop or other system to avoid exposure.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

5.2.3 ES 5 - CS 3: Control of worker exposure: Industrial use (Use in closed,

continuous process with occasional controlled exposure) (PROC2)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : Use in closed, continuous process with occasional controlled
exposure
No specific measures identified.
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 67(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

5.2.4 ES 5 - CS 4: Control of worker exposure: Industrial use (Use in closed batch

process (synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
Remarks : Use in closed batch process (synthesis or formulation)
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Remarks : Use in batch and other process (synthesis) where opportunity
for exposure arises

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed batch process (synthesis or formulation)
measures

Note : Use in batch and other process (synthesis) where opportunity

for exposure arises
No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

5.2.5 ES 5 - CS 5: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at non
dedicated facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 68(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Both hands
Covers skin contact area up to : 960 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : inhalative
Technical conditions and : Local exhaust ventilation
measures
Effectiveness (of a measure) : 90 %
Personal protective measures : If technical measures not practical:
Wear respiratory protection.
Effectiveness (of a measure) : 90 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

5.2.6 ES 5 - CS 6: Control of worker exposure: Industrial use (Transfer of substance

or preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa
Physical Form (at time of use) : Low volatile liquid
Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year
Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use
Outdoor / Indoor : Indoor use
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 69(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Risk Management Measures

Note : No specific measures identified.

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

5.3. ES 5 Exposure estimation and reference to its source

5.3.2 ES 5 - CS 2: Worker exposure: Industrial use (Use in closed process, no

likelihood of exposure) (PROC1)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,03 mg/m³ (ECETOC TRA v2.0 worker) 0,0007
- local and systemic
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,003
systemic
combined routes ECETOC TRA v2.0 worker 0,004

5.3.3 ES 5 - CS 3: Worker exposure: Industrial use (Use in closed, continuous

process with occasional controlled exposure) (PROC2)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,01
systemic
combined routes ECETOC TRA v2.0 worker 0,08

5.3.4 ES 5 - CS 4: Worker exposure: Industrial use (Use in closed batch process

(synthesis or formulation), Use in batch and other process (synthesis) where
opportunity for exposure arises) (PROC3, PROC4)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 7,76 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,22
- local and systemic batch process (synthesis or formulation))
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed batch process (synthesis or formulation))
combined routes ECETOC TRA v2.0 worker, Use in closed batch process 0,23
(synthesis or formulation)
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 70(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Use in batch 0,37
- local and systemic and other process (synthesis) where opportunity for
exposure arises)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,06
systemic batch and other process (synthesis) where opportunity for
exposure arises)
combined routes ECETOC TRA v2.0 worker, Use in batch and other 0,43
process (synthesis) where opportunity for exposure
arises

5.3.5 ES 5 - CS 5: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 2,59 mg/m³ (ECETOC TRA v2.0 worker) 0,07
- local and systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,13
systemic
combined routes ECETOC TRA v2.0 worker 0,20

5.3.6 ES 5 - CS 6: Worker exposure: Industrial use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities, Transfer of substance or preparation into small containers (dedicated filling
line, including weighing)) (PROC8b, PROC9)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities)
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation (charging/discharging)
from/to vessels/large containers at dedicated facilities)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation (charging/discharging)
from/to vessels/large containers at dedicated facilities)
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation (charging/discharging) from/to vessels/large
containers at dedicated facilities
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation (charging/discharging) from/to vessels/large
containers at dedicated facilities
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation into small containers (dedicated
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 71(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

filling line, including weighing))

Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,37
- local and systemic substance or preparation into small containers (dedicated
filling line, including weighing))
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation into small containers
(dedicated filling line, including weighing))
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation into small containers
(dedicated filling line, including weighing))
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation into small containers (dedicated filling line,
including weighing)
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,43
preparation into small containers (dedicated filling line,
including weighing)

5.4. ES 5 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario
ECHA guidance for downstream users
Section 2

6. ES 6: Professional use; Anti-freeze and de-icing

products
6.1. Titles of Contributing scenarios (CS)

Environment
CS1: Professional use (Wide dispersive outdoor use of processing aids in ERC8d
open systems)
Workers
CS2: Professional use (Use in closed process, no likelihood of exposure, Use PROC1, PROC2
in closed, continuous process with occasional controlled exposure)
CS3: Professional use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS4: Professional use (Transfer of substance or preparation PROC8b
(charging/discharging) from/to vessels/large containers at dedicated
facilities)
CS5: Professional use (Spraying outside industrial settings and/or PROC11
applications)

6.2. ES 6 Conditions of use affecting exposure

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 72(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

6.2.1 ES 6 - CS 1: Control of environmental exposure: Professional use (Wide

dispersive outdoor use of processing aids in open systems) (ERC8d)

Remarks : As no environmental hazard was identified no environmental-

related exposure assessment and risk characterization was
performed.

6.2.2 ES 6 - CS 2: Control of worker exposure: Professional use (Use in closed

process, no likelihood of exposure, Use in closed, continuous process with
occasional controlled exposure) (PROC1, PROC2)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
Remarks : Use in closed process, no likelihood of exposure, Use in
closed batch process (synthesis or formulation)
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Remarks : Use in closed, continuous process with occasional controlled
exposure

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed process, no likelihood of exposure
measures Sample via a closed loop or other system to avoid exposure.

Technical conditions and : Use in closed, continuous process with occasional controlled
measures exposure

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 73(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

6.2.3 ES 6 - CS 3: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
non dedicated facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Both hands
Covers skin contact area up to : 960 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : inhalative
Technical conditions and : Local exhaust ventilation
measures
Effectiveness (of a measure) : 80 %
Personal protective measures : If technical measures not practical:
Wear respiratory protection.
Effectiveness (of a measure) : 80 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

6.2.4 ES 6 - CS 4: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
dedicated facilities) (PROC8b)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 74(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

6.2.5 ES 6 - CS 5: Control of worker exposure: Professional use (Spraying outside

industrial settings and/or applications) (PROC11)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Amount used
Amounts used : 0,05 L/min

Frequency and duration of use

Exposure duration : 150 min
Frequency of use : <= 5 days per week

Human factors not influenced by risk management

Dermal exposure : Whole body

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use
Room size : <= 1000 m3

Risk Management Measures

Personal protective measures : Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training.
Effectiveness (of a measure) : 90 %

Personal protective measures : Wear suitable protective clothing.

Wear suitable coveralls to prevent exposure to the skin.
Effectiveness (of a measure) : 80 %

Personal protective measures : Wear a respirator conforming to EN140.

Effectiveness (of a measure) : 40 %

Organisational measures to : Ensure that direction of application is only horizontal or

prevent /limit releases, dispersion downward.
and exposure

Organisational measures to : Ensure that the distance from worker to task is greater than 1
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 75(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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prevent /limit releases, dispersion m.

and exposure

Organisational measures to : Ensure that the direction of airflow is clearly away from the
prevent /limit releases, dispersion worker.
and exposure
Note : Not applicable

Organisational measures to : Provide enhanced general ventilation by mechanical means.

prevent /limit releases, dispersion
and exposure

Organisational measures to : Regular cleaning of work area

prevent /limit releases, dispersion
and exposure

Organisational measures to : Regular cleaning of equipment

prevent /limit releases, dispersion
and exposure

Organisational measures to : Ensure regular inspection, cleaning and maintenance of

prevent /limit releases, dispersion equipment and machines.
and exposure

Organisational measures to : Ensure that the task is not carried out by more than one
prevent /limit releases, dispersion worker simultaneously.
and exposure

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

6.3. ES 6 Exposure estimation and reference to its source

6.3.2 ES 6 - CS 2: Worker exposure: Professional use (Use in closed process, no

likelihood of exposure, Use in closed, continuous process with occasional controlled
exposure) (PROC1, PROC2)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,03 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,0007
- local and systemic process, no likelihood of exposure)
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed process, no likelihood of exposure)
combined routes ECETOC TRA v2.0 worker, Use in closed process, no 0,004
likelihood of exposure
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Use in closed, 0,37
- local and systemic continuous process with occasional controlled exposure)
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,01
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 76(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

systemic closed, continuous process with occasional controlled

exposure)
combined routes ECETOC TRA v2.0 worker, Use in closed, continuous 0,38
process with occasional controlled exposure

6.3.3 ES 6 - CS 3: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 13,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,13
systemic
combined routes ECETOC TRA v2.0 worker 0,50

6.3.4 ES 6 - CS 4: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at dedicated
facilities) (PROC8b)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 25,88 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,74
- local and systemic substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities)
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation (charging/discharging)
from/to vessels/large containers at dedicated facilities)
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,80
preparation (charging/discharging) from/to vessels/large
containers at dedicated facilities

6.3.5 ES 6 - CS 5: Worker exposure: Professional use (Spraying outside industrial

settings and/or applications) (PROC11)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 14,05 mg/m³ (Stoffenmanager v4.0) 0,40
- local and systemic
Worker - dermal, long-term - 53,75 mg/kg bw/day (RISKOFDERM v2.1) 0,51
systemic
combined routes Not applicable 0,91

6.4. ES 6 Guidance to Downstream User to evaluate whether he

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 77(82)

Substance key: 000000478216 Revision Date: 03.06.2016
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works inside the boundaries set by the Exposure Scenario

7. ES 7: Professional use; Use in functional fluids

7.1. Titles of Contributing scenarios (CS)

Environment
CS1: Professional use (Wide dispersive indoor use of substances in closed ERC9a, ERC9b
systems, Wide dispersive outdoor use of substances in closed systems)
Workers
CS2: Professional use (Use in closed process, no likelihood of exposure, Use PROC1, PROC2,
in closed, continuous process with occasional controlled exposure, Use PROC3
in closed batch process (synthesis or formulation))
CS3: Professional use (Use in batch and other process (synthesis) where PROC4
opportunity for exposure arises)
CS4: Professional use (Transfer of substance or preparation PROC8a
(charging/discharging) from/to vessels/large containers at non dedicated
facilities)
CS5: Professional use (Transfer of substance or preparation into small PROC9
containers (dedicated filling line, including weighing))
CS6: Professional use (Heat and pressure transfer fluids in dispersive use but PROC20
closed systems)

7.2. ES 7 Conditions of use affecting exposure

7.2.1 ES 7 - CS 1: Control of environmental exposure: Professional use (Wide
dispersive indoor use of substances in closed systems, Wide dispersive outdoor use
of substances in closed systems) (ERC9a, ERC9b)

Remarks : As no environmental hazard was identified no environmental-

related exposure assessment and risk characterization was
performed.

7.2.2 ES 7 - CS 2: Control of worker exposure: Professional use (Use in closed

process, no likelihood of exposure, Use in closed, continuous process with
occasional controlled exposure, Use in closed batch process (synthesis or
formulation)) (PROC1, PROC2, PROC3)
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according to Regulation (EC) No. 1907/2006

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Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of one hand
Covers skin contact area up to : 240 cm²
Remarks : Use in closed process, no likelihood of exposure, Use in
closed batch process (synthesis or formulation)
Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²
Remarks : Use in closed, continuous process with occasional controlled
exposure

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Technical conditions and : Use in closed process, no likelihood of exposure
measures Sample via a closed loop or other system to avoid exposure.

Technical conditions and : Use in closed, continuous process with occasional controlled
measures exposure

Technical conditions and : Use in closed batch process (synthesis or formulation)

measures With occasional controlled exposure

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

7.2.3 ES 7 - CS 3: Control of worker exposure: Professional use (Use in batch and

other process (synthesis) where opportunity for exposure arises) (PROC4)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 79(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

7.2.4 ES 7 - CS 4: Control of worker exposure: Professional use (Transfer of

substance or preparation (charging/discharging) from/to vessels/large containers at
non dedicated facilities) (PROC8a)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Both hands
Covers skin contact area up to : 960 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Exposure routes : inhalative
Technical conditions and : Local exhaust ventilation
measures
Effectiveness (of a measure) : 80 %
Personal protective measures : If technical measures not practical:
Wear respiratory protection.
Effectiveness (of a measure) : 80 %

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

7.2.5 ES 7 - CS 5: Control of worker exposure: Professional use (Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)) (PROC9)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 80(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

7.2.6 ES 7 - CS 6: Control of worker exposure: Professional use (Heat and pressure

transfer fluids in dispersive use but closed systems) (PROC20)

Product characteristics
Concentration of the Substance in : <= 100 %
Mixture/Article

Physical Form (at time of use) : Low volatile liquid

Vapour pressure : 0,123 hPa

Frequency and duration of use

Exposure duration : <= 480 min
Frequency of use : <= 240 days per year

Human factors not influenced by risk management

Dermal exposure : Palm of both hands
Covers skin contact area up to : 480 cm²

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor use

Risk Management Measures

Note : No specific measures identified.

Additional good practice advice beyond the REACH Chemical Safety Assessment
Additional good practice advice : Wear solely goggles.

7.3. ES 7 Exposure estimation and reference to its source

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 81(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

7.3.2 ES 7 - CS 2: Worker exposure: Professional use (Use in closed process, no

likelihood of exposure, Use in closed, continuous process with occasional controlled
exposure, Use in closed batch process (synthesis or formulation)) (PROC1, PROC2,
PROC3)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 0,03 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,0007
- local and systemic process, no likelihood of exposure)
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed process, no likelihood of exposure)
combined routes ECETOC TRA v2.0 worker, Use in closed process, no 0,004
likelihood of exposure
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker, Use in closed, 0,37
- local and systemic continuous process with occasional controlled exposure)
Worker - dermal, long-term - 1,37 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,01
systemic closed, continuous process with occasional controlled
exposure)
combined routes ECETOC TRA v2.0 worker, Use in closed, continuous 0,38
process with occasional controlled exposure
Worker - inhalative, long-term 7,76 mg/m³ (ECETOC TRA v2.0 worker, Use in closed 0,22
- local and systemic batch process (synthesis or formulation))
Worker - dermal, long-term - 0,34 mg/kg bw/day (ECETOC TRA v2.0 worker, Use in 0,003
systemic closed batch process (synthesis or formulation))
combined routes ECETOC TRA v2.0 worker, Use in closed batch process 0,23
(synthesis or formulation)

7.3.3 ES 7 - CS 3: Worker exposure: Professional use (Use in batch and other

process (synthesis) where opportunity for exposure arises) (PROC4)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 25,88 mg/m³ (ECETOC TRA v2.0 worker) 0,74
- local and systemic
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,06
systemic
combined routes ECETOC TRA v2.0 worker 0,80

7.3.4 ES 7 - CS 4: Worker exposure: Professional use (Transfer of substance or

preparation (charging/discharging) from/to vessels/large containers at non dedicated
facilities) (PROC8a)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

CORRTREAT 12286 Page 82(82)

Substance key: 000000478216 Revision Date: 03.06.2016
Version : 4 - 0 / EU Date of printing : 15.09.2016

Worker - dermal, long-term - 13,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,13
systemic
combined routes ECETOC TRA v2.0 worker 0,50

7.3.5 ES 7 - CS 5: Worker exposure: Professional use (Transfer of substance or

preparation into small containers (dedicated filling line, including weighing)) (PROC9)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 25,88 mg/m³ (ECETOC TRA v2.0 worker, Transfer of 0,74
- local and systemic substance or preparation into small containers (dedicated
filling line, including weighing))
Worker - dermal, long-term - 6,86 mg/kg bw/day (ECETOC TRA v2.0 worker, Transfer 0,06
systemic of substance or preparation into small containers
(dedicated filling line, including weighing))
combined routes ECETOC TRA v2.0 worker, Transfer of substance or 0,80
preparation into small containers (dedicated filling line,
including weighing)

7.3.6 ES 7 - CS 6: Worker exposure: Professional use (Heat and pressure transfer

fluids in dispersive use but closed systems) (PROC20)

Route of exposure and type Exposure estimate RCR

of effects
Worker - inhalative, long-term 12,94 mg/m³ (ECETOC TRA v2.0 worker) 0,37
- local and systemic
Worker - dermal, long-term - 1,71 mg/kg bw/day (ECETOC TRA v2.0 worker) 0,02
systemic
combined routes ECETOC TRA v2.0 worker 0,39

7.4. ES 7 Guidance to Downstream User to evaluate whether he

works inside the boundaries set by the Exposure Scenario