MATERIAL SAFETY DATA SHEET

Propiconazole Technical

SECTION -1 : CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

Trade Name: Propiconazole Technical

Manufacturer Name & Address: Meghmani Industries Limited

27, GIDC Industrial Estate,
Phase-I, Vatva, Ahmedabad-382445
Tel: +91 2583 1050
Mobile No: +91 8155002069, 8155002071
Fax: +91 79 2589 3495

Corporate Office: 301, White Cross, 15 Patel Society,

GulbaiTekra Road, Panchvati,
Ahmedabad-380 006, Gujarat (India)
Phone No: +91 79 26562827, 26569901
Fax: +91 79 26422600, 26463999

SECTION – 2 : COMPOSITION, INFORMATION ON INGREDIENTS

Common name: Propiconazole Technical

CA Name: (±)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
IUPAC Name: (±)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-Ylmethyl]-1H-1,2,4-triazole
CAS Number: [60207-90-01]

Chemical Family: Triazole Fungicide

Molecular Formula: C15H17Cl2N3O2
Molecular Weight: 342.2
Product Use:
Propiconazole is a systemic fungicide which inhibits the biosynthesis of ergosterol by fungi.
Ergosterol is a vitamin-like compound needed by fungi to form their cell walls. According to the
manufacturer, propiconazole is both a preventative and curative fungcide. It is used on grasses
grown for seed, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots,
peaches, nectarines, plums and prunes. On cereals Propiconazole controls diseases caused by
Erysiphe graminis, Leptosphaeria nodorum, Pseudocerosporella herpotrichoides, Puccinia spp.,
Pyrenophora teres, Rhynchosporium secalis, and Septoria spp.
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Composition:
CAS No. Chemical Name Percent (% by w/w) EINECS No.
262-104-4
[60207-90-01] Propiconazole 95%
Other organic Impurities 05%

SECTION - 3 : HAZARDS IDENTIFICATION

Skin Contact
May irritate skin. The dermal toxicity of this product is low. However, skin contact should be
avoided. This product is not a skin sensitizer.
Eye Contact
This product may be mildly irritating to eyes. However, it is unlikely to cause any more than mild
transient discomfort. It is also unlikely to cause any lasting effects.
Inhalation
May be a slight respiratory irritant.
Ingestion
The acute toxicity of this product is low, but it may be harmful if a large amount is swallowed.
Environmental

Slight toxic to aquatic organisms.

Fire and Explosion
Flammable at high Temperature

SECTION - 4 : FIRST AID MEASURES

Inhalation:
Remove to fresh air. If not breathing, follow standard resuscitation practices.
Skin contact:

Flush with soap and water, remove contaminated clothing, and seek medical attention.
Eye Contact:

Flush with plenty of water for at least 15 min. seek medical attention if irritation begins and / or
persists.

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Ingestion: Drink 1-2 glasses of water, induce vomiting, seek medical attention. Do not induce
vomiting or give anything by mouth to an unconscious person.
Advice to physician:
The following symptoms may occur: Local – slight skin and eye irritation. Systemic – none
documented over many years’ experience. For local contamination treatment should be
symptomatic after decontamination. In case of skin or eye contamination, treat as documented
under “First Aid”. If a large amount of this product is fully conscious and it is less than 30min.
since ingestion. Monitor blood count; Gastric lavage, Charcoal administration. Treat
symptomically.

SECTION - 5 : FIRE FIGHTING MEASURES

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH
(approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Suitable Extinguishing Media:
In case of fire, use water spray, foam, dry powder, carbon dioxide or sand. Keep nearby containers
and equipment cool with a water stream.
Special Hazards arising from the substance or mixture:
Wear self- contained breathing apparatus. If area is heavily exposed to fire and if conditions
permit, let fire burn itself out since water may cause increase contamination hazard.
Unusual Fire and Explosion Hazards:
Toxic and flammable fumes. Do not release chemically contaminated water in to drains, soil and
surface waters.
Advice for firefighters:
Whenever this product involved in a major fire, firefighters to wear boots, overalls, gloves, eye and
face protection and breathing apparatus. Keep containers cool with water spray. Water should be
used only to cool the unaffected stock.

SECTION - 6 : ACCIDENTAL RELEASE MEASURES

Personal precautions: Safety glasses or goggles, rubber gloves, shoes plus socks, long-sleeved
shirt, and long pants.
Environmental precautions: Prevent the contamination of the floor and of beds of water.
Cleaning methods: Clear the liquid formation. Transfer to a properly labeled deposit that will be
closed and sealed until the recovery of climination of the product.

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SECTION -7 : HANDLING AND STORAGE

Handling:
Do not apply to humans, their clothing, or bedding. Do not contaminate food or use on household
tanks.
Storage:
Technical protective measures: store in original container only in cool, dry, well-ventilated, secure
area at minimum storage temperature and out of reach of children and animals.

SECTION - 8 : EXPOSURE CONTROLS, PERSONAL PROTECTION

Control parameters:
Components with workplace control parameters:
Exposure controls:

Appropriate Engineering Controls:

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after
handling the product.
Personal Protective Equipment:
Eye/face Protection:
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin Protection:
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection:
Complete suit protecting against chemicals, the type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory Protection:
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air

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respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
SECTION - 9 : PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid

Appearance: Yellowish, Viscous Liquid.
Odor: Odorless,

Density/Sp gr: 1.29 g/ml (20 0C)

Boiling Point: 120°C
Flash Point: above 1000C
Viscosity: No data available
Auto Ignition Temperature: No data available
Oxidizing Properties: No data available
Explosive Properties: No data available
Combustibility: No data available
Corrosiveness: No data available

Solubility: In water 100 mg/l (20 ºC). In n-hexane 47 g/l. Completely miscible with ethanol,
acetone, toluene and n-octanol (25 °C).
Vapor Pressure: 2.7 10-2 mPa (20 °C); 5.6 10-2 mPa
x x

Partition Coefficient: KOW log P = 3.72 (pH 6.6, 25 ºC)

Other information: Henry 9.2 X 10-5 Pa m3 mol-1 (20 °C, calc.)

SECTION - 10 : STABILITY AND REACTIVITY

Stability:
Stable for at least 2 years at ambient temperatures.
Chemical Stability: Stable up to 320 0C; no significant hydrolysis.
Conditions to Avoid: Open flames, sparks, ignition sources, and dampness.
Incompatibility: Strong acids, oxidizers, dampness (in storage).
Hazardous Polymerization: Not available

Hazardous Decomposition Products: Toxic and flammable fumes produced: oxides of nitrogen,
and carbon.

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SECTION -11 : TOXICOLOGICAL INFORMATION

Acute Oral:
LD50 for rats 1517, mice 1490 mg/kg.
Acute Inhalation:

LC50 (4 h) for rats >5800 mg/m3.

Acute Eye & Skin Irritation:

Acute percutaneous LD50 for rats >4000, rabbits >6000 mg/kg. Non-irritating to skin and eyes
(rabbits). No sensitization (guinea pigs).
Carcinogenicity: No carcinogenic potential of relevance for human exposure.
Teratogenicity: Not teratogenic.

Mutagenicity: Not mutagenic.

SECTION - 12 : ECOLOGICAL INFORMATION

Ecotoxicology:
Birds:
Acute oral LD50 for Japanese quail 2223, bobwhite quail 2825, mallard ducks >2510, Pekin
ducks >6000 mg/kg. LC50 (8 d) for Japanese quail >1000, bobwhite quail >5620, mallard ducks
>5620, Pekin ducks >1000 ppm.
Fish:
LC50 (96 h) for carp 6.8, rainbow trout 5.3, golden orfe 5.1, spot 2.6 mg/l.
Daphnia: EC50 4.8 mg/l.
Algae:
EC50 0.02-13.6 mg/l for three freshwater algae and two diatom species.
Other aquatic spp.:
LC50 (96 h) for crayfish 42 mg/l. EC50 (96 h) for mysid shrimp Mysidopsisbahia) 0.5 mg/l.
Bees:

Not toxic to bees; LD50 (contact and oral) >100 g/bee.

~

Worms: No toxic effects against Lumbricus rebellus.

Persistence/ Degradability:
Propiconazole is stable in water. Propiconazole is not persistent in soil.
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Mobility in Soil:
Propiconazole has low to medium mobility in soil.
Bioaccumulative Potential:
Propiconazole has low to medium potential to bioaccumulation.

SECTION - 13 : DISPOSAL CONSIDERATIONS

Product : Do not reuse product containers. Dispose of product containers, waste containers, and
residues according to local, state and environment and regulations.
Waste Disposal Method :
In accordance with local, provincial and federal regulations. Packaging should be disposed off at a
specialized chemical waste. Contact regional environment agency.
Other:
Emergency eye wash and shower.

SECTION - 14 : TRANSPORT INFORMATION

UN Number:
ADR/RID: 3082 IMDG: 3082 IATA: 3082
UN Proper Shipping Name:
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Propiconazole)

IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Propiconazole)

IATA: Environmentally hazardous substance, liquid, n.o.s. (Propiconazole)

Transport Hazard Class(es):

ADR/RID: 9 IMDG: 9 IATA: 9

Packaging Group:
ADR/RID: III IMDG: III IATA: III

Environmental Hazards:
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes

Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Propiconazole Technical)

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Environmental risk : Not Harmful

Environmental
Propiconazole designated as marine

SECTION - 15: REGULATORY

Classification of the substance or mixture:

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute toxicity, Oral (Category 4)
Skin sensitization (Category 1)
Acute aquatic toxicity (Category
1) Chronic aquatic toxicity
(Category 1)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Harmful if swallowed. May cause sensitization by skin contact. Very toxic to aquatic organisms,
may cause long-term adverse effects in the aquatic environment.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram

Signal word Warning

Hazard statement(s)
H302 Harmful if swallowed.
H317 May cause an allergic skin reaction.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P273 Avoid release to the environment.
P280 Wear protective gloves.
P501 Dispose of contents/ container to an approved waste disposal plant.
Supplemental Hazard none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)

R-phrase(s)
R22 Harmful if swallowed.
R43 May cause sensitization by skin contact.
Very toxic to aquatic organisms, may cause long-term adverse
R50/53 effects in
the aquatic environment.
S-phrase(s)

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 S36/37 Wear suitable protective clothing and gloves.
If swallowed, seek medical advice immediately and show this
S46 container or
label.
This material and its container must be disposed of as hazardous
S60 waste.
Avoid release to the environment. Refer to special instructions/
S61 Safety
data sheets

SECTION - 16: ADDITIONAL INFORMATION

MSDS Creation Date: 06/01/2010

Revision Date: 10/07/2013

To the best of Meghmani Industries Ltd’s knowledge, the above information is true and accurate
as of the date of preparation of this material safety data sheet. The above information is not
intended to be exhaustive. Additional or other information may be required depending on actual
conditions of use and handling. Meghmani Industries Ltd make no warranties, expressed or
implied and shall not be liable for any damages or injury, howsoever caused, arising out of the use
of this data sheet.