Cambridge IGCSE™

BIOLOGY 0610/22
Paper 2 Multiple Choice (Extended) May/June 2021
45 minutes

You must answer on the multiple choice answer sheet.

*9597819231*

You will need: Multiple choice answer sheet

Soft clean eraser
Soft pencil (type B or HB is recommended)

INSTRUCTIONS
 There are forty questions on this paper. Answer all questions.
 For each question there are four possible answers A, B, C and D. Choose the one you consider correct
and record your choice in soft pencil on the multiple choice answer sheet.
 Follow the instructions on the multiple choice answer sheet.
 Write in soft pencil.
 Write your name, centre number and candidate number on the multiple choice answer sheet in the
spaces provided unless this has been done for you.
 Do not use correction fluid.
 Do not write on any bar codes.
 You may use a calculator.

INFORMATION
 The total mark for this paper is 40.
 Each correct answer will score one mark.
 Any rough working should be done on this question paper.

This document has 16 pages. Any blank pages are indicated.

IB21 06_0610_22/3RP
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1 What is a characteristic of all living organisms?

A breathing
B circulation
C egestion
D sensitivity

2 The bonobo and the chimpanzee are two closely related species.

What is the most accurate method of deciding how closely related species are?

A compare evolutionary relationships of other species

B compare the base sequences of their DNA
C compare their anatomy
D compare their morphology

3 Scientists discover a new species of animal.

It has a segmented body with two pairs of legs on each segment.

To which group of animals does this new species belong?

A arachnids
B crustaceans
C insects
D myriapods

4 Which part of a cell makes glucose?

A cell membrane
B chloroplast
C nucleus
D vacuole

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5 The diagram shows some of the blood vessels and other structures in the human body.

The blood vessels shown are all parts of the same

A cell.
B organ.
C organ system.
D tissue.

6 A photograph shows a plant cell nucleus measuring 2 mm across.

If the magnification of the cell is 500, what is the actual size of the nucleus?

A 0.00002 mm B 0.004 mm C 0.04 mm D 250 mm

7 By which process do oxygen and carbon dioxide move between cells and capillaries?

A breathing
B diffusion
C excretion
D respiration

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8 Which process is involved in the uptake of glucose by the epithelial cells of kidney tubules?

A active transport
B osmosis
C translocation
D transpiration

9 Which element is found in proteins but not carbohydrates?

A carbon
B hydrogen
C nitrogen
D oxygen

10 The sequence of the bases present on one strand of a DNA molecule is shown.

ATTGGACGGT

Which sequence shows the bases present on the opposite strand?

A CGGTTCATTG
B TCCAATGAAC
C TAACCTGCCA
D ATTGGACGGT

11 Starch is digested by amylase in the mouth, but it is not digested in the stomach.

What is the reason for this?

A All starch digestion is completed in the mouth.

B The pH in the stomach is not suitable for the amylase to work.
C The starch does not stay in the stomach long enough to be digested.
D The temperature in the stomach is not suitable for the amylase to work.

12 Which statement about an enzyme-controlled reaction is correct?

A During the reaction, the substrate changes into products.

B The enzyme is gradually used up during the reaction.
C The enzyme is slowly broken down during the reaction.
D The higher the temperature, the slower the reaction.

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13 A plant with striped leaves was kept in bright light for six hours.

white stripe

green stripe

A leaf was taken from the plant and the chlorophyll was removed. The leaf was then tested for
starch using iodine solution.

Which diagram shows the result of the test?

A B C D
yellow-brown white blue-black yellow-brown

blue-black blue-black green green

14 The graph shows daily carbon dioxide uptake and transpiration by the plant Agave americana.

The plant is adapted to live in very dry conditions.

10 0.6
CO2 uptake
8
0.4 transpiration
CO2 uptake 6
/ g H 2O
/ mg per dm2
transpiration per dm2
per hour 4
0.2 per hour
2

0 0
0 4 8 12 16 20 24
time of day / hours

What can be concluded from this graph?

A More stomata are closed during dark periods.

B More stomata are closed during light periods.
C There is no carbon dioxide uptake during dark periods.
D There is no water uptake during light periods.

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15 Statements 1 to 4 describe stages in the development of cholera.

1 Chloride ions are secreted into the gut.

2 Osmosis causes water to move into the gut.
3 The infected person becomes dehydrated.
4 Toxins are produced by the pathogenic bacteria.

What is the correct sequence of the four stages?

A 1234

B 1432

C 4123

D 4132

16 The diagram shows part of the human body.

Which statement about organs X and Y is correct?

A X absorbs more water from food than Y.

B X does not absorb water from food.
C Y absorbs more water from food than X.
D Y does not absorb water from food.

17 Which sequence describes the pathway taken by water as it moves through a plant?

A root hair cell  xylem  root cortex cell  mesophyll

B mesophyll  xylem  root cortex cell  root hair cell

C root cortex cell  root hair cell  xylem  mesophyll

D root hair cell  root cortex cell  xylem  mesophyll

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18 The diagram shows a plant at different times of year.

stage 1 At the start of the growing season, the plant uses the food reserves stored in
the bulb for the growth of shoots and leaves.
stage 2 Later in the season, the leaves of the plant photosynthesise and the food
reserves in the bulb are replaced.

new growth of photosynthesising

shoots and leaves leaves

food reserves
in the bulb
bulb containing being replaced
food reserves

stage 1 stage 2

What is the role of the bulb during stage 1 and stage 2?

stage 1 stage 2

A sink sink
B sink source
C source sink
D source source

19 How does blood enter the heart?

A through arteries into the atria

B through arteries into the ventricles
C through veins into the atria
D through veins into the ventricles

20 What is the sequence of organs that blood passes through during one circulation of the body of a
fish?

A muscle  heart  gill  muscle

B muscle  gill  heart  muscle

C muscle  heart  gill  heart  muscle

D muscle  gill  heart  gill  muscle

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21 A child is vaccinated against measles. After a period of time the child is infected with the measles
virus.

The graph shows the concentration of measles antibodies in the child’s bloodstream during this
time.

antibody
concentration
in the blood

time

Which statement is consistent with the information in the graph?

A After the vaccination, the child produced memory cells.

B The child had passive immunity against measles.
C The measles virus contains antibodies.
D The vaccination failed to protect the child against measles.

22 Which sequence of changes takes place when we breathe in?

A diaphragm contracts  volume of thorax increases  pressure in lungs decreases

B diaphragm contracts  volume of thorax increases  pressure in lungs increases

C diaphragm relaxes  volume of thorax increases  pressure in lungs decreases

D diaphragm relaxes  volume of thorax increases  pressure in lungs increases

23 What is the link between muscle contraction, protein synthesis and the maintenance of a constant
body temperature?

A They are controlled by hormones.

B They are examples of homeostasis.
C They require energy.
D They require carbon dioxide.

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24 After vigorous exercise, an athlete continues to breathe deeply during the recovery period.

During this recovery period the oxygen debt is removed.

Which reaction is used to remove the oxygen debt?

A aerobic respiration of lactic acid in the liver

B aerobic respiration of lactic acid in the muscles
C anaerobic respiration of lactic acid in the liver
D anaerobic respiration of lactic acid in the muscles

25 The diagram shows some of the organs in the human body.

Which row matches the function to the correct organ?

excretes carbon
excretes urea produces urea
dioxide

A 1 2 3
B 1 3 2
C 2 3 1
D 2 1 3

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26 What is the result of the release of adrenaline?

blood glucose
breathing rate
concentration

A decreases decreases
B decreases increases
C increases decreases
D increases increases

27 A person's skin looks more red in a warm environment than it does in a cool environment.

Which explanation is correct?

A The arterioles supplying capillaries in the skin vasodilate and less blood flows to the skin
surface.
B The arterioles supplying capillaries in the skin vasodilate and more blood flows to the skin
surface.
C The arterioles supplying capillaries in the skin vasoconstrict and more blood flows to the skin
surface.
D The arterioles supplying capillaries in the skin vasoconstrict and less blood flows to the skin
surface.

28 The diagram shows a plant next to a window.

light

Which statement explains the plant shoot’s growth?

A There is a higher concentration of auxin in the cells on the shaded side of the shoot. This
prevents cell elongation.
B There is a higher concentration of auxin in the cells on the shaded side of the shoot. This
stimulates cell elongation.
C There is a lower concentration of auxin in the cells on the shaded side of the shoot. This
prevents cell elongation.
D There is a lower concentration of auxin in the cells on the shaded side of the shoot. This
stimulates cell elongation.

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29 The graph shows how smoking different numbers of cigarettes for different lengths of time affects
the risk of lung cancer.

45 key
40
smoking less than 20 cigarettes per day
35
smoking more than 20 cigarettes per day
30
risk of lung cancer 25
/ arbitrary units 20
15
10
5
0
< 20 20–29 30–39 40–49 > 50
number of years smoking

Which conclusions are supported by the data in the graph?

1 Smoking more than 20 cigarettes per day always increases the risk of lung cancer
more than smoking less than 20 cigarettes per day.
2 Smoking cigarettes for more years increases the risk of lung cancer.
3 Smoking more than 20 cigarettes per day for more than 50 years has the highest
risk of lung cancer.

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

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30 The life cycle of aphids includes both sexual and asexual reproduction.

parent
offspring

reproduction
X
fertilised egg

reproduction
Y female offspring
parent

male
parent

Which statement is correct?

A X shows asexual reproduction, which produces genetic variation in the offspring.

B Y shows asexual reproduction, which produces genetic variation in the offspring.
C X shows asexual reproduction, which produces genetically identical offspring.
D Y shows asexual reproduction, which produces genetically identical offspring.

31 Modern agricultural methods often use artificial insemination (AI) to breed dairy cattle.

Which statement describes the process of artificial insemination?

A Sperm is collected from a bull and frozen. The sperm is later inserted into the vagina of a
cow.
B Eggs are removed from a cow and fertilised using sperm from a bull. The fertilised eggs are
reinserted into the uterus of the cow.
C Male and female cows with desired characteristics are chosen to mate.
D Embryos are removed from the uterus of the cow. The embryos are frozen and stored for
future use.

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32 The Tasmanian devil is an animal with seven pairs of chromosomes in each body cell.

The diagram shows the chromosomes in a cell from a Tasmanian devil.

Which statement is correct?

A The cell is a haploid cell containing pairs of chromosomes.

B The cell is a diploid cell with no pairs of chromosomes.
C The cell is a haploid cell with no pairs of chromosomes.
D The cell is a diploid cell containing pairs of chromosomes.

33 Some statements about mitosis are listed.

1 Cells divide and produce new cells to repair damaged tissues.

2 Chromosomes are duplicated and the cell separates to form gametes.
3 Chromosomes are duplicated and the cell separates to form genetically identical
cells.
4 Mitosis is used in asexual reproduction.

Which statements are correct?

A 1, 2 and 3 B 1, 3 and 4 C 2 and 4 D 3 and 4 only

34 Coat colour in cattle is controlled by two codominant alleles.

The genotype CRCR results in cattle with a red coloured coat. The genotype CWCW results in cattle
with a white coloured coat. The genotype CRCW results in a roan coat; these cattle have a mixture
of red hairs and white hairs in their coat.

A mating occurs between a red cow and a roan bull.

What is the expected ratio of coat colour in the offspring?

A 50% red, 50% white

B 100% red
C 50% red, 50% roan
D 100% roan

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35 Which feature would help a plant to survive in a dry environment?

A large leaves
B many stomata
C small roots
D thick waxy cuticle

36 What occurs as a result of artificial selection?

A antibiotic resistance in bacteria

B disease resistant crops
C presence of roots in cactus plants
D sickle cell anaemia

37 Which type of energy is passed from organism to organism in a food chain?

A light
B chemical
C heat
D kinetic

38 The diagram shows a food web.

brown trout

dragonfly
nymph
mayfly freshwater
nymph shrimp

microscopic
pondweed alga

How many organisms feed at more than one trophic level?

A 0 B 1 C 2 D 3

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39 Bacteria can be used to make human proteins.

Which statement explains why this is possible when a human gene is placed in a bacterial cell?

A Bacteria are able to reproduce rapidly.

B Bacteria are very small organisms.
C Bacteria contain genetic material in plasmids.
D Bacteria have the same genetic code as humans.

40 The process of eutrophication begins with the increased availability of nitrate ions and other ions
in water.

The processes involved in eutrophication are listed.

1 increased aerobic respiration by decomposers

2 increased death of producers due to lack of light
3 rapid growth of producers
4 oxygen concentration in the water decreases and more organisms die

What is the correct sequence?

A 3214

B 3421

C 4123

D 4132

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