APPICON Abstracts
APPICON Abstracts
Aim And Objective: Hpylori is a prevalent pathogen of human and chronic infection of gastric mucosa results
in gastritis, Peptic Ulcer Disease(PUD), MALT lymphoma and gastric adenocarcinoma. Epidemiological studies
have demonstrated a higher frequency of blood group O and nonsecretors in PUD. Since H pylori is an established
etiological factor of PUD, an association of ABO and Secretor phenotype with Hpylori was established. To evaluate
the frequency of ABO and secretor phenotype in patient suffering from PUD and to crosscheck whether they were
infected with H pylori.
Materials And Methods: A retrospective study was done in 86 PUD patients who underwent endoscopy and urea
breath test for detection of H pylori, which was confirmed by PCR in biopsy samples from September 2012 to Aug
2013 in Gauhati Medical College and Hospital. ABO phenotype was determined by standard hemagglutination
test and secretor phenotype was determined by hemagglutination inhibition test of saliva.
Result: Out of 86 patients suffering from PUD, 90.3% were blood group O and 61.62% were non secretors. Also,
among 56 patients infected with H pylori, 64.2% were nonsecretors.
Conclusion: Result suggests that H pylori infection can be related to blood group O nonsecretors.
Key Words: PUD:Peptic Ulcer Disease, H pylori: Helicobacter pylori, Secretors and nonsecretors.
Despite of the advances in the treatment of coronary artery disease, acute myocardial infarction is one of the
leading causes of morbidity and mortality worldwide in both men and women. Tea is a beverage that has been
consumed from time immemorial for its supposed stimulating and detoxifying properties. Bio-tea (Kombucha)
is prepared by the fermentation of tea by using a symbiotic association of acetic acid bacteria and yeast. The
present study compares the cardioprotective effect of tea and Bio-tea in Isoproterenol (ISO)-induced myocardial
infarcted rats. The pretreatment was carried out in male Albino Wistar rats for a period of 30 days followed
by subcutaneous injection of Isoproterenol (85mg/kg body weight). Along with these, normal rats as well as
Isoproterenol induced myocardial infarcted rats were also used which served as controls. ISO-induced rats
showed a significant increase in the activities of marker enzymes such as creatine kinase, creatine kinase-MB,
lactate dehydrogenase, aspartate transaminase and alanine transaminase in the serum and a subsequent decrease
of the same in the heart. A marked reduction was observed in the concentration of markers enzymes in the serum
with a simultaneous increase of the same in the heart tissue in rats pretreated with either tea or Bio-tea. However
the present study indicated that Bio-tea possessed higher cardioprotective potential than tea.