Physiology Workbook
Physiology Workbook
RAJAJINAGAR, BENGALURU-10.
DEPARTMENT OF PHYSIOLOGY
Work Book on Charts, Problems and Case history
NAME
ROLL NO.
BATCH
YEAR
1
2
CHARTS
3
4
5
6
7
Identify the graph
8
9
1. Identify the diagram
2. What is the importance of myosin head?
3. What is a cross bridge?
4. What are the functions of sarcotubular system?
10
11
1. What is shown in the above diagram inside the blood vessel?
2. What is exposed below the endothelial cells?
3. Which pathway is activated in response to this event?
4. Name the first factor which is converted to active form.
12
13
14
15
16
17
18
19
1. Label the various parts.
2. What are the degrees of heart block?
3. Write the conduction velocities in each of these tissues.
1 2 3 heart block
20
1. Identify and label the diagram.
2. Explain the ionic basis of pacemaker potential.
3. What is the effect of vagal stimulation on pace maker tissue?
4. What is vagal tone?
21
1. Identify the graph. Label them.
2. What are the causes of different phases?
22
a. What does this graph depict?
b. Add the units to the numbers on the left side of the graph.
c. Identify each of these graphs.
23
1. Identify the diagram.
2. Name the areas
3. Add a note on heart sounds.
24
Percussion
wave in
arterial
ejection durin
systole
Dicpotic
wave
rebound
of blood
in andclosed
1. Identify the graph label.
2. What are the aortic
causes of different phases?
3. What is Radiofemoral delay and in which condition is it seen?
valv
during
diastolic
Notch
closure
of aortic
val
25
26
Pulmonary hypertension causes jvp raised
27
28
1. Identify the graph.
2. Identify all the parts and label them.
29
30
1. Name the event.
2. Write the events in all five diagrams.
3. Correlate to ECG.
31
32
1. Identify the diagram.
2. Name the various layers of this.
P
3. Write the values of pO2 & pCO2 in arteries & veins.
33
34
Volume
Pressure
Intra
pulmonary
pressure
1. Identify the different graphs.
2. Write the muscles of inspiration.
3. How the tranverse, longitudinal & vertical diameter increase during inspiration?
35
36
1. Identify the graph
2. Label the diagram from 1 to 7 and write their normal values.
37
38
1. Identify the graph.
2. Write the units on X- axis and Y- axis.
3. What is the P50?
4. What are the advantages of steep lower portion and flat upper portion?
39
40
1. Identify the diagram.
2. What are the effects of sections at various levels?
3. Where is the rhythmicity originated?
41
42
43
44
A fev1
A fev2
45
46
47
48
49
50
51
52
53
54
55
56
57
58
1. Identify the condition.
2. What is the cause of diabetes in
this condition?
3. What are somatomedins?
4. What is the action on growth?
5. Write three differences between
pituitary dwarfism and cretinism.
59
60
61
62
63
64
1. Identify the condition.
2. Name the clinical features of this
condition.
3. What is the action of this
hormone on CNS.
65
66
1. Identify the condition.
2. Mention the important clinical
features of the condition.
3. What is myxedema madness?
4. Mention the steps involved in
synthesis of thyroid hormones.
67
68
69
70
1. Label the stages of oogenesis.
2. What is the role of LH on ovulation?
3. What is Corpus luteum?
4. What are the actions of progesterone?
71
72
73
74
1. Mention the tests done for detection of ovulation.
2. What is the cause of increase in basal body temperature after ovulation.
3. What is LH surge?
75
76
1. What does these graph depict?
2. The dark line graph is for what?
3. The grey line graph is for what?
4. Write three functions of each.
77
78
1. Identify the picture & explain.
2. Mention the different methods which serve as ovulation indicators.
3. What is Mittelschmerz?
4. What is Spinnbarkeit?
79
80
1. Identify the diagram.
2. What is the innervation of Gastrointestinal tract?
3. What is the effect of sympathetic & parasympathetic stimulation on
motility?
81
82
1. Identify the diagram.
2. What is Sham feeding?
3. What are the differences between Pavlov’s pouvch & Heidenains
pouch?
4. What are the phases of gastric secretion?
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
1. Label the parts.
2. Write the components of basal ganglia.
3. Write any 2 afferent & efferent connections of basal ganglia.
4. What is the role of basal ganglia in the maintenance of rigidity.
5. Write any 2 hypokintetic and 2 hyperkinetic features of parkinsonism.
6. What is the role of L Dopa in parkinson’s disease treatment?
103
104
105
106
107
108
109
110
111
112
113
114
1. What are the receptors for stimulation of vestibular apparatus?
2. Trace the vestibular pathway.
115
116
1. Identify the diagrams and label the parts.
2. What is near point? Why it recedes.
3. How accommodation occurs for a near object.
4. What is the role of ciliary muscle in accommodation.
117
118
1. Identify the diagram and label the parts.
2. What is blind spot?
3. Where is the crossing of optic fibres?
4. Where is the lesion in homonymous and heteronymous hemianopia?
5. Where exactly is the synapse of optic fibers in midbrain and thalamus?
119
PROBLEMS
120
GENERAL PHYSIOLOGY
121
2 Calculate the extra cellular fluid(ECF)Volume
122
3) Calculate the interstitial fluid volume from the following data;
4- Define odema.
123
4) Calculate the sucrose space from the following data and calculate total
body water;
3- What are the other substances which can be used to measure ECF
volume?
124
RENAL SYSTEM:
125
6) Calculate the renal plasma flow from the following data
126
7) Calculate the inulin clearance
127
8) Calculate the Net filtration pressure from the following data and calculate
GFR.
1. Define GFR
2. Name 2 conditions where Glomerular hydrostatic pressure
is increased
3 .Name 2 conditions where Glomerular oncotic pressure is increased.
128
9) Calculate the GFR from the following data,
Filtration pressure= 10 mm Hg
1. Define GFR
2. Name 2 conditions where Glomerular hydrostatic pressure is increased
3. Name 2 conditions where Glomerular oncotic pressure is increased.
4. What is filtration coefficient?
5. Name the conditions which increase Bowman’s capsule hydrostatic
pressure.
129
RESPIRATORY SYSTEM:
Case Tidal vol(ml). Resp. Rate/min Min. vent(litres) Dead space (ml)
1 150 40 6L 150
2 500 12 6L 150
3 1000 6 6L 150
130
11) Calculate the breathing reserve & Dyspnoeic index
131
12) Calculate the respiratory dead space volume
132
13) Calculate the functional residual capacity (FRC) from the given data.
133
14) Calculate the amount of oxygen delivered to tissues from the following
data.
134
15) Find out the Inspiratory capacity from the following data
135
16) Calculate the respiratory minute volume and alveolar ventilation from
the following data
136
17) Which of the following is likely to have airway obstruction?
137
CARDIOVASCULAR SYSTEM:
138
19) Calculate the cardiac output & cardiac index
139
20) Calculate the cardiac index from the following data.
140
21) Calculate the ejection fraction from the following data.
141
22) Calculate Mean Arterial pressure from the following data.
b. Diastolic BP = 90 mm Hg.
142
23. Calculate MCV and MCH from the following data:-
PCV = 28%
RBC count = 4 Million cells/mm3
Hb = 9 gm%
143
24. A patient has the following values –
Hb = 10 gm%
RBC count = 3 million cells /mm3
PCV = 25%
Calculate his MCV, MCH, & MCHC and comment on the above values.
144
CASE HISTORY
145
Blood –
Investigations revealed
Achlorhydria by histamine augmented test
RBC count = 3 million cells/mm3, irregular in size & shape
Leucopenia
Thrombocytopenia
QUESTIONS:
146
2. A 3-year-old male child was brought to the doctor with complaints of
bleeding profusely with trivial injury. Careful history revealed similar
bleeding tendency in male relatives.
QUESTIONS:
147
3. A term female newborn is noted to have oedema, dyspnoea, cyanosis
and marked jaundice. Mother is AB negative. Her previous childbirth
was an uneventful full-term vaginal delivery. The mother did not
receive any subsequent immunizations after her first delivery. On
examination, there was pallor, marked jaundice, hypotonia,
hepatosplenomegaly, and generalized oedema.
QUESTIONS:
What is your diagnosis? Discuss.
148
4. During a physiology practical class, a student was found to have a
reticulocyte count of 5%. Questioning revealed that he had donated
blood a few days back.
QUESTIONS:
1. Comment on his reticulocyte count.
2. What response is he showing?
3. What is the physiology underlying this response?
149
5.A healthy subject went to spend his vacation at Darjeeling. After 3
weeks stay, his PCV was found to be 60%.
QUESTIONS:
150
6.A child from a low-income group shows the following features:
a. Reduced Haemoglobin
b. Hook worm infestation
QUESTIONS:
151
7. A woman aged 30 years complains of general fatigue, breathlessness on
exertion, giddiness and palpitation. On examination, patient had pallor of
skin and mucous membrane, glossitis and koilonychia.
Investigations revealed:
Haemoglobin : 6gm/100ml
RBC count : 3million cells/cumm of blood
MCHC : 28%
MCV : 60 cubic microns
WBC : Eosinophilia
Stool examination: Hookworm ova present.
Questions –
a. To which morphological classification of Anaemia, the case belongs?
b. To which etiological classification of Anaemia, the case belongs?
c. Write any two other causes of anaemia.
d. What is a microcyte?
e. What is the exact role of Vit B12 and folic acid in erythropoiesis?
f. What is the normal Hb content?
g. Write the breakdown product of Hb. Write its normal value.
152
II CARDIOVASCULAR SYSTEM:
8) A lady complained of swelling in the feet from the last 2 days only. It was pitting in
nature. Blood pressure was normal. Swelling receded in 2 days. On the previous day of her
visit to the doctor, she had under taken a long distance bus journey.
QUESTIONS:
1. What is the cause of edema in this case?
2. What are the other causes of edema?
153
9) An individual met with an accident and suffered severe blood loss and was brought to
the hospital. On examination, he showed the following signs:
QUESTIONS:
1. What is your diagnosis?
2. How do you explain the signs & symptoms?
3. What immediate treatment will you suggest?
154
III RESPIRATORY SYSTEM:
10) A premature infant was admitted with severe dyspnoea and cyanosis. The cardio
vascular system was found to be normal.
QUESTIONS:
155
11) A patient with congestive cardiac failure was admitted in the intensive care unit. He
is seen to breathe rapidly for a few minutes followed by a short period of apnea.
QUESTIONS:
156
IV ENDOCRINE SYSTEM:
12) A young girl aged 9 years is very short statured for her age.
QUESTIONS:
157
13) A 37 year old woman complains of diplopia and blurred vision. She also has lactation
with altered menstrual cycle. MRI scan revealed a pituitary mass.
QUESTIONS:
158
14) A male aged 40 years complains of severe joint pains, widening of spaces between
teeth is seen; his nose, hands and feet are unusually large. He reveals that his shoe size
has increased from 10 to size 16.
QUESTIONS:
159
15) A patient comes with history of excess drinking water and passing of excess colorless
urine frequently. He is markedly dehydrated with water deprivation.
Investigation revealed that patient passed 15L of urine in 24 hrs. Specific gravity of urine
was 1002-1004, with no sugar or albumin.
QUESTIONS:
160
16) A middle aged man complains of weakness, polyuria , polydypsia & increased
appetite. He also has poor wound healing.
Investigations revealed:
QUESTIONS:
161
17) A patient was admitted to the hospital with multiple fractures after a fall.
QUESTIONS:
162
18) Mrs ‘Q’aged 39 years complains of polyuria (frequent urination), nocturia (urination
during night). Also complains of weakness of muscles, change in the Voice and deepening
of voice recently, excess hair growth over face and body, amenorrhea (stoppage of
monthly menstruation). On examination, face is seen round and puffy, arms and legs
appear thin, purple striae are seen over abdomen. Her blood pressure was 160/104mm of
Hg. Fasting blood Sugar was 148mg/100ml of blood. Wound healing was poor.
QUESTIONS:
163
19) A 22 year old married woman has been menstruating regularly.
QUESTIONS:
164
20) A newly married lady wants to know if she has conceived.
QUESTIONS:
165
21) Semen analysis of a male aged 30 years reveals tail less sperms, many non motile
sperms and a sperm count of 10 million per ml.
QUESTIONS:
166
22) A couple in their mid-thirty’s has two healthy children and decide to have no more
children. They seek advice on contraception from a doctor.
QUESTIONS:
167
V GASTRO INTESTINAL SYSTEM:
23) A middle aged man had extensive resection of his ileum for malignancy. Following this
he complains of loss of weight and of passing bulky stools. Examination of the patient
revealed hypoproteinemia and evidences of multiple vitamin deficiencies.
QUESTIONS:
168
24) A man 35 years old complains on and off epigastric pain for the past 3 years. Pain
increases after his meals.
QUESTIONS:
169
25) On the 4th post-operative day, a patient complains of not passing stools since surgery.
He complained abdominal distension with spasmodic pain. On examination, bowel sounds
are absent.
QUESTIONS:
170
26) A patient comes to a doctor with history of yellowish discoloration of skin and mucous
membrane. Stool was clay colored and foul smelling.
Investigations revealed:
QUESTIONS:
171
27) A chronic alcoholic patient showed the following on clinical examination,
– Severe jaundice
– Increased clotting time
– Increased alkaline phosphate level of blood
QUESTIONS:
172
VI MUSCLE NERVE PHYSIOLOGY, CENTRAL NERVOUS SYSTEM and SPECIAL SENSES:
QUESTIONS:
173
29) A student complained that he is not able to see what was written on the blackboard
by the teacher.
QUESTIONS:
174
30) A 50 year old woman complained that she couldn’t read news paper while keeping
the paper at normal distance.
QUESTIONS:
175
31) A man aged 25 years was disqualified for the post of engine driver, as he could not
recognized green light.
QUESTIONS:
176
32) A man walks to E.N.T out patient department complaining of deafness from the last 3
months. During history taking, it was found out that he is suffering from pulmonary
tuberculosis and is on anti-tubercular treatment from the last 6 months.
QUESTIONS:
177
33) Following repeated middle ear infections on the left side, a little girl complained of
some hearing impairment. On examination, the Rinne’s test showed that bone conduction
was better than air conduction on the left side.
QUESTIONS:
178
34) A 69 year old man goes to the physician. He observes tremors in his hand and fingers.
His face is unexpressive, makes few movements. He walks slowly without swinging his
arms. His speech is monotonous and muscles exhibit rigidity.
QUESTIONS:
179
35) A man in neurology OPD was seen walking like a drunkard. He had slurred speech On
examination, there was hypotonic, pendular knee jerk, nystagmus.
QUESTIONS:
180
36) An elderly man woke up one morning to find that the limbs on the right side of his
body were paralysed. The muscles became spastic. On chewing food, he found that the
food collected on the right side of the mouth.
QUESTIONS:
181
37) A middle aged man was found to have unsteadiness of gait with eyes closed.
Sensations were impaired in the lower limbs. Light reflex was absent but constriction of
pupils occurred on accommodation.
QUESTIONS:
182
38) Mother of 6 year old child noticed weakness in her child’s lower limb muscles.
Weakness progressed to flaccidity of the lower limb muscles. Child had a history of fever
for 5-6 days with severe headache. CSF examination revealed viral infection.
QUESTIONS:
183
AMPHIBIAN GRAPHS
184
Identify the graph and explain.
185
Identify the graph and explain.
186
Identify the graph and explain.
187
Identify the graph and explain.
188
Identify the graph and explain.
189
Identify the graph and explain.
190
Identify the graph and explain.
191
Identify the graph and explain.
192
Identify the graph and explain.
193
Identify the graph and explain.
194
Identify the graph and explain.
195
Identify the graph and explain.
196
Identify the graph and explain.
197
Identify the graph and explain.
198