EDL Uganda 2001
EDL Uganda 2001
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All parts of this publication may be reproduced in any form, provided due acknowledgement is given
ISBN 9970-719-00-9
Foreword
It is my pleasure to present this revised and updated Essential Drugs list for Uganda (EDLU) 2001 to
all prescribing and dispensing staff, and to other health professionals handling medicines in Uganda.
This 3rd edition of EDLU has been produced in order to take account of the various changes which
have taken place in therapeutic practice over the 5 year period since the last edition.
Essential drugs are those which satisfy the needs of the majority of the population and should
therefore always be available in adequate amounts and appropriate dose forms. EDLU lists those
essential drugs considered to be the most appropriate for use in the Uganda public health system. It is
also strongly recommended as a rational basis for private sector prescribing.
In order to ensure that the correct decision is taken on whether to include a particular item or not,
consideration must be made of a number of key criteria including:
Efficacy: the capacity of the medicine effectively to treat the diagnosed condition
Safety: the therapeutic index of the drug (ratio of treatment dose to toxic dose) and
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Appropriateness: the overall suitability of the medicine within the local context
taking account of various factors including:
In preparing the new EDLU, these criteria have been carefully considered by the Committee on
Essential Drugs (CED), assisted as required by experts in the various medical specialities.
Drug lists by their very nature are subject to rapid obsolescence due to ever-changing therapeutic
requirements for the treatment of conditions found in Uganda. A good example of this is the
treatment of malaria which has had to be revised recently to take account of rapidly developing
resistance to previous first-line medication.
Thus the list should be subject to constant scrutiny and updated accordingly. This process is highly
dependent on the input of clinicians in the field who should therefore continuously assess the
appropriateness of the selected medicines for treating the conditions encountered. Clinicians are
encouraged to submit proposals for amendments to EDLU following the procedures given in the
Preface.
The EDLU is a guide for drug selection and level of distribution and is meant to be used together
with the National Standard Clinical Guidelines (NSCG) which give practical guidance on diagnosis
and appropriate therapeutic approaches. Both publications are also useful resource materials for
training in all aspects of rational drug use.
I wish to thank the Chairman and members of the National Drug Authority Committee on Essential
Drugs for the time and effort they have put into the production of this excellent and vital document.
It is my sincere hope that routine use of the EDLU in combination with the NSCG by all levels of
prescriber in their daily work will greatly assist in ensuring that patients receive optimum treatment
of their health problems at all times.
However this will only be possible if adequate quantities of the recommended drugs are constantly
available for utilisation at the appropriate level of health unit.
The Ministry of Health is therefore committed to improving accessibility to required essential drugs
through active implementation of the new National Drug Policy which aims inter alia at securing
adequate funding of essential drugs procurement and improved management of the drug supply
system at all levels.
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Dr C W C B Kiyonga MP
Hon. Minister of Health
The first and second editions of EDLU were produced in 1991 and 1996 respectively. As with these
previous editions which it now supersedes, this new EDLU 2001 is produced with the aim of
assisting in making accessible and affordable to the majority of the population those drugs which are
necessary for the prevention and treatment of common health problems in the country.
The EDLU lists those essential drugs considered to be most suitable for current use in Uganda. The
current WHO model list (11th revision December 1999) was used as a basis for EDLU and modified
to suit the requirements of Uganda according to the criteria given in the Foreword by the Honourable
Minister of Health, and taking into account available resources and currently applicable clinical
practice.
According to the National Drug Policy the EDLU is a ‘primary drug management tool at all levels of
the health system’ and is intended to ‘to strengthen and harmonise the essential drugs selection
process at national and district levels for both public and private sectors’. The EDLU should be used
‘as a basis for procurement, prescribing and dispensing in the public health system and its use
promoted in the private (profit and non-profit) sector’.
Thus it is important to stress that, although the list is designed primarily for public sector use, it is
equally appropriate for private sector prescribers who are strongly encouraged to select EDLU
drugs whenever possible. Numerous changes have been made to EDLU to bring it into line with
currently accepted therapeutic requirements. These are summarised on pages xix-xxvi.
As stated in the Foreword, the EDLU will be subject to constant review and revision. All clinicians
should therefore fully familiarise themselves with the contents of the EDLU and continuously
evaluate its relevance and appropriateness to their daily work.
Proposals for amendments to EDLU, together with supporting arguments and any available relevant
literature, should be forwarded in writing to:
The Chairman
National Drug Authority Committee on Essential Drugs
PO Box 23096, Kampala
Tel: 255665 / 255628 / 347391 / 347392
Fax: 255758
Email nda@imul.com
According to the National Drug Policy, the EDLU is supposed to be revised at least every three
years, thus the next edition should be produced by 2004.
In the meantime, any proposals will be discussed by the Committee on Essential Drugs. Agreed
amendments to the list will be notified to all prescribers through Ministry of Health circulars as
appropriate.
3. Acknowledgements
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Preparation of this vital publication would not have been possible without the dedication and hard
work of my fellow contributing members of the Committee on Essential Drugs who are listed on
pages xv-xvi and without the invaluable contributions of the key clinical specialists listed on page
xvii. I wish to express my sincere thanks to them all for their time and efforts.
I am also greatly indebted to the Chairman and Executive Secretary / Registrar of NDA for
facilitating the completion of this work through the provision of a most suitable and supportive
working environment and to the NDA Secretariat staff for their continuous technical and
administrative support.
Dr A Lukanga-Ndawula
MB ChB, FRCS(Ed)
Chairman, NDA Committee on Essential Drugs
2. Dr E Owino
3. Dr G W Zirembuzi
Chairman, NDA
5. Prof G R Nzarubara
6. Dr C W Kadama
Private Medical Practitioner, Centenary Clinic, Kampala representing the Private Medical
Practitioners Association
7. Ms D A Kusemererwa
8. Dr E K Kanyesigye
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9. Mr G K Sematiko
10. Dr B A Mpeka-Tusubira
11. Dr S Ndyanabangi
13. Dr J C Lule
14. Mr C J Forshaw
Psychiatrist,
Butabika Hospital, Kampala
2. Prof T Clshoz
Professor of Anaesthesiology,
University Hospital, Mbarara
Dept. of Ophthalmology,
Makerere Medical School, Mulago Hospital, Kampala
4. Dr J V B Tindimwebwa
5. Mr E K Naddumba
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Presentation of Information
1. General
Drug names: the relevant International Non-proprietary Name (INN) or generic name are used
throughout the list. According to the National Drug Policy and Authority Statute 1993 sec 12 generic
names shall be used for prescribing and labelling (ie. including dispensing) of drugs, except where
no such generic or suitable alternative non-proprietary name exists.
Order of sections: drugs are arranged in alphabetical order by pharmacological / therapeutic groups
following the same basic arrangement as the WHO Model List of Essential Drugs with the addition
of two additional sections: 28: Ear, Nose and Oropharyngeal Preparations and 29: Drugs for
Neurosurgical Use.
2. Level of Use
For each item the lowest level of health care facility at which the item may be used is indicated as
shown in the table below. This designation is in line with the diagnostic and clinical skills expected
to be available at that level. In certain cases the use of an item is further restricted to facilities where
a specific type of clinical and/or diagnostic expertise is available, eg. certain ophthalmological
preparations. The in-charge of each level of Health Centre is given in parentheses.
Notes:
1. Diagnostic facilities: Health facilities of levels HC3 and higher have different degrees of
laboratory diagnostic support facilities available.
2. Drug availability: all of the items listed for health centre levels up to and including H (Hospital)
level are expected to be available at all times from National Medical Stores. More specialised items
with an R (Restricted) or Ref (Referral) designation will be available from NMS only at the request
of the relevant institution. It is therefore important that accurate estimates for the annual
requirements for these items are made by the institutions concerned well in advance and the
information forwarded to NMS so that sufficient quantities of the required items may be procured
and held in stock.
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L = litre = 1,000 mL
mL = millilitre = 0.001 L
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B. Deletions
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1Soda lime must be available for CO2 absorption during closed circuit general
anaesthesia
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2. ANALGESICS, ANTIPYRETICS
2.1 Non-opioids
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4. ANTIDOTES
4.1 General
4.2 Specific
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6. ANTI-INFECTIVE DRUGS
6.1 Anthelmintics
6.1.2 Antifilarials
6.1.3 Antischistosomals
6.2 Antibacterials
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7. ANTIMIGRAINE DRUGS
7.2 Prophylaxis
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9. ANTI-PARKINSONISM DRUGS
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13.5 Scabicide
13.6 Pediculicide
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15.1 Antiseptics
15.2 Disinfectants
16. DIURETICS
17.2 Antiemetics
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17.3 Antihaemorrhoidals
17.4 Antispasmodics
17.5 Laxatives
17.6.2 Antidiarrhoeals1
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18.2 Androgens
18.4 Oestrogens
18.7 Progestogens
norethisterone tablet 5 mg H
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19. IMMUNOLOGICALS<sup>2</sup>
2 See individual product literature for more information
19.3 Vaccines
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21.5 Mydriatics1
21.6 Astringents1
22.1 Oxytocics
22.2 Antioxytocics
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26.2 Parenterals
26.3 Miscellaneous
1Contains: nicotinamide 40mg, pyridoxine HCl 4mg, riboflavine 4mg, thiamine HCl
10mg/2mL amp
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clotrimazole solution 1% H
gentamicin ear drops 0.3% H
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