Minutes of the Meeting for Syllabus Discussion of T.Y.B.Pharm.

Sem V R-2019 Pharmacology-II Theory and Pharmacology-II

Practical syllabus held online on Wednesday, 23rd June 2021 at 2.00 pm

Organizer: SJIPR, Palghar

Subject Experts:
Dr. Vandana Panda (KMKCP, Colaba) - Chairperson
Dr. Deepak Bharati (SJIPR, Palghar) -Coordinator
Dr. Priti Patel (DLHHCOP, Ulhasnagar)
Mrs. Pradnya Korlekar (VESCOP, Chembur)

Following are the recommendations arising from the discussion in the meeting of the subject experts with representative members of
different Pharmacy Colleges:

BP503.T. PHARMACOLOGY-II (Theory)

Unit Topic Hours Recommendations

I Pharmacology of drugs acting on 10 ● I.a Self Study: Conduct quiz on this topic
cardiovascular system ● For b to f: Cover Classification
a. Introduction to hemodynamic and ● Cover MOA, ADR & Application of each class of drugs
electrophysiology of heart. ● Descriptive Questions should be based on classification and
b. Drugs used in congestive heart failure particular classes of drugs
c. Anti-hypertensive drugs. ● Descriptive Questions based on individual drugs should NOT
d. Anti-anginal drugs. be asked
e. Anti-arrhythmic drugs. ● MCQ on prototype drugs based on peculiar
f. Anti-hyperlipidemic drugs. ADR/Application/classification can be asked

II 1. Pharmacology of drugs acting on 10 ● Cover Classification

cardiovascular system ● Cover MOA, ADR & Application of each class of drugs

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 a. Drug used in the therapy of shock. ● Descriptive Questions should be based on classification and
b. Hematinics, coagulants and anticoagulants. particular classes of drugs
c. Fibrinolytics and anti-platelet drugs ● Descriptive Questions based on individual drugs should NOT
d. Plasma volume expanders be asked
2. Pharmacology of drugs acting on urinary ● MCQ on prototype drugs based on peculiar
system ADR/Application/classification can be asked
a. Diuretics
b. Anti-diuretics.

III 3. Autocoids and related drugs 10 ● Cover Classification

a. Introduction to autacoids and classification ● Cover MOA, ADR & Application of each class of drugs
b. Histamine, 5-HT and their antagonists. ● Cover DMARDs in Antirheumatic drugs
c. Prostaglandins, Thromboxanes and ● Descriptive Questions should be based on classification and
Leukotrienes. particular classes of drugs.
d. Angiotensin, Bradykinin and Substance P. ● Descriptive Questions based on individual drugs should NOT
e. Non-steroidal anti-inflammatory agents be asked
f. Anti-gout drugs ● MCQ on prototype drugs based on peculiar
g. Antirheumatic drugs ADR/Application/classification can be asked

IV 4. Pharmacology of drugs acting on endocrine 8 ● 4.a Self Study: Conduct quiz on this topic
system ● 4.b Anterior Pituitary : Mention hormones and its uses and
a. Basic concepts in endocrine pharmacology. cover only Growth Hormone in detail (For Descriptive
b. Anterior Pituitary hormones- analogues and question ask only on Growth Hormone )
their inhibitors. ● 5 d. Only hormones to be covered and not the synthetic
c. Thyroid hormones- analogues and their agents
inhibitors. ● Cover Classification
d. Hormones regulating plasma calcium level- ● Cover MOA, ADR & Application of each class of drugs
Parathormone, Calcitonin and ● Descriptive Questions should be based on classification and
Vitamin-D. particular classes of drugs
d. Insulin, Oral Hypoglycemic agents and ● Descriptive Questions based on individual drugs should NOT
glucagon. be asked
e. ACTH and corticosteroids. ● MCQ on prototype drugs based on peculiar
ADR/Application/classification can be asked

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V 5. Pharmacology of drugs acting on endocrine 7 ● 5. Cover Classification
system ● Cover MOA, ADR & Application of each class of drugs
a. Androgens and Anabolic steroids. ● Descriptive Questions should be based on classification and
b. Estrogens, progesterone and oral particular classes of drugs.
contraceptives. ● Descriptive Questions based on individual drugs should NOT
c. Drugs acting on the uterus. be asked
● MCQ on prototype drugs based on peculiar
6. Bioassay ADR/Application/classification can be asked
a. Principles and applications of bioassay.
b.Types of bioassay ● 6 a & b Can be covered in Lab
c. Bioassay of insulin, oxytocin, vasopressin, ● 6 C : Cover only those which are not covered in lab
ACTH,d-tubocurarine,digitalis, histamine
and 5-HT

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 Blue Print

Considering Online Mode: 40 Marks MCQ + 40 Marks Descriptive

Unit Topic MCQ - Descriptive - 40 marks Total

40
Marks

I Pharmacology of drugs acting on 6 12M Difficult + M Easy 22

cardiovascular system (10 Hours)

II Hematology (10 Hours) 8 8M Medium 18

III Autocoids and related drugs (10 Hours) 4 12M Difficult + M Easy 20

IV Pharmacology of drugs acting on 10 8M Medium 18

endocrine system (8 Hours)

V Reproductive endocrinology 10 8M Easy 18

Bioassay (7 Hours)

Please Note: No question on Physiology and Self Study Topics. For Self Study topics - Quiz to be taken
Refer to Syllabus discussion MOM above for topic specific resolutions

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 Considering Online Mode: 20 Marks MCQ + 60 Marks Descriptive

Unit Topic MCQ - Descriptive - 40 marks Total

40
Marks

I Pharmacology of drugs acting on 2 12M Difficult + 12M Easy 26

cardiovascular system (10 Hours)

II Hematology (10 Hours) 4 12M Medium 16

III Autocoids and related drugs (10 Hours) 2 12M Difficult 26

+ 12M Easy

IV Pharmacology of drugs acting on 6 12M Medium 18

endocrine system (8 Hours)

V Reproductive endocrinology 6 12M Easy 18

Bioassay (7 Hours)

MCQ 2 D
8M
10 E

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 Blue Print

Considering Offline Mode: 75 Marks (PCI paper pattern)

Unit Topic MCQ - Long Answers Short Answers Total

20*1=20 (Answer 2 out of 3) (Answer 7 out of 9)
Marks 2 x 10 = 20 Marks 7 x 5 = 35 marks

I Pharmacology of drugs acting on 4 10 5+5 24

cardiovascular system (10 Hours)

II Hematology (10 Hours) 4 10 5 19

III Autocoids and related drugs (10 5 10 5 20

Hours)

IV Pharmacology of drugs acting on 3 5+5+5 18

endocrine system (8 Hours)

V Reproductive endocrinology 4 5+5 14

Bioassay (7 Hours)

Please Note: No question on Physiology and Self Study Topics. For Self Study topics - Quiz to be taken
Refer to Syllabus discussion MOM above for topic specific resolutions

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 BP 507 P. PHARMACOLOGY-II (Practical)

All laboratory techniques and animal experiments are demonstrated by simulated

experiments from softwares and videos

Sr No. Particular

1 Introduction to in-vitro pharmacology and physiological salt solutions.

2 Effect of drugs on isolated frog heart.

3 Effect of drugs on blood pressure and heart rate of dog.

4 Study of diuretic activity of drugs using rats/mice.

5 DRC of acetylcholine using frog rectus abdominis muscle.

6 Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis
muscle and rat ileum respectively.

7 Bioassay of histamine using guinea pig ileum by matching method.

8 Bioassay of oxytocin using rat uterine horn by interpolation method.

9 Bioassay of serotonin using rat fundus strip by three point bioassay.

10 Bioassay of acetylcholine using rat ileum/colon by four point bioassay.

11 Determination of PA2 value of prazosin using rat anococcygeus muscle (by Schilds plot
method).

12 Determination of PD2 value using guinea pig ileum.

13 Effect of spasmogens and spasmolytics using rabbit jejunum.

14 Anti-inflammatory activity of drugs using carrageenan induced paw-edema model.

15 Analgesic activity of drug using central and peripheral methods

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Additional Recommendations:
Following resources can be explored:
1. Link for MSBTE Pharmacology Toxicology manual:
https://curriculum.msbte.ac.in/msbteacmon/curdev/outer.php?q=get_lab_manuals
2. Contact Detail for ExPharmacology Software suggested by Ms. Tatheer Fatima: Dr. Dharmendra Ahuja - 9636348191
3. Practical Manual of Experimental and Clinical Pharmacology by Bikash Medhi for Pharmacology Lab II suggested by Tanmay
Patwardhan
4. Fundamentals of Experimental Pharmacology by M.N. Ghosh for Pharmacology Lab II suggested by Ms. Vaibhavi Garge
5. Experimental Pharmacology and Toxicology by Dr. Vrushabendra Swamy, S. Chand Publication

Dr. Vandana Panda

Chairperson
Syllabus Discussion Committee for T.Y. B. Pharm. Pharmacology II