Acid Base Study Guide
Acid Base Study Guide
Hi New Friend!
In this acidbase guide you’ll find brevity in only some of the highest yield “mustknow”
content for your exams. This one is solely focused on basics of acid base.
For even more content or to be able to remember all of these facts (and more) simply
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● pH
○ Normal Blood: 7.
35
7.
45
○ Low Numbers (Acidosis) High Numbers (Alkalosis)
● CO2 (Carbonic ACID)
○ Normal: 35 45
○ CO2 is ACIDIC
○ Primarily regulated by LUNGS/RESPIRATORY
○ ****Remember that you BLOW OFF CO2
■ Breathing faster and deeper will blow off more CO2
● Decreasing acid in body
■ Not breathing will cause a BUILDUP of CO2
● Increasing acid in body
○ You can remember pH and CO2 by remembering 7 and 3545 since they are the same.
● HCO3 (Bicarbonate)
■ Normal: 22 26
■ HCO3 is BASIC/ ALKALINE
■ Primarily regulated by KIDNEYS/ METABOLIC
■ Slow to respond (Requires about 1224 hours to compensate and change levels)
HOW TO INTERPRET:
■ Step 1: Evaluate pH
● Below 7.35 = Decreasing (Acidic)
● Above 7.45 = Increasing (Alkalotic)
● MAKE LITTLE ARROWS AND WRITE DOWN HALF OF YOUR ANSWER
(ACIDIC/ALKALOTIC)
■ Step 2: Evaluate CO2
● Below 35 = Decreasing
● Above 45 = Increasing
● CO2 = Controlled by Lungs = You Blow off CO2 = by breathing IN and OUT in
OPPOSITE directions. “Respiratory Opposite”
■ HCO3 = Controlled by kidneys = You pee our bicarb = by letting it all go out one
direction.
Disorder Overview
● Respiratory Acidosis
● Respiratory Alkalosis
● Metabolic Acidosis
■ Often seen in ESRD, Diabetic Ketoacidosis, Lactic Acidosis
■ Think DOWN, DOWN, DOWN
■ Decreased pH, Decreased CO2, Decreased HCO3
■ These patients will immediately attempt to balance their low amount of HCO3 with their
respiratory status by blowing off CO2:
● Kussmaul's Breathing (Hyperventilation)
■ Metabolic Acidosis Labs
● pH = DOWN
● CO2 = DOWN
● HCO3 = DOWN
● Metabolic Alkalosis
■ Often seen in patients with excessive vomiting, diarrhea, excessive antacid use, diuretics
● They lose too much acid and have too much HCO3
■ Think UP, UP, UP!
■ Increased pH, Increased CO2, Increased HCO3
■ These patients may attempt to compensate by decreasing respirations to build up acid in
an attempt to correct pH.
■ Metabolic Alkalosis Labs
● pH = UP
● CO2 = UP
● HCO3 = UP
LEARN THE
PICMONICS
TAKE A
QUIZ
VIEW AN
INTRO VIDEO