Scribd
Upload
41 views10 pages

2.enzyme L-2

Uploaded by

MD IMRAN HOSSEN
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
41 views10 pages

2.enzyme L-2

Uploaded by

MD IMRAN HOSSEN
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 10

SDET in Chemical Engineering

ChE 4779

Sustainable Development &


Emerging Technologies in
Chemical Engineering
Mahbuba Jannat, PhD
Assistant Professor
Dept. of Chemical Engineering, BUET

Prepared by Dr. Jannat


SDET in Chemical Engineering

Enzyme
• Enzymes are protein molecule which play important role in biological
processes such as food digestion, wound healing, blood clotting, etc.

• Bio-makers of different diseases: HIV, heart diseases, metastatic


cancer, etc.
Without Enzyme

With Enzyme

Energy
Substrate Enzyme product
Reaction progress Prepared by Dr. Jannat
SDET in Chemical Engineering

Source of enzyme

https://slideplayer.com/slide/17605196/ Prepared by Dr. Jannat


SDET in Chemical Engineering

Specificity of Enzyme

https://ib.bioninja.com.au/standard-level/topic-2-molecular-biology/25-enzymes/enzyme-experiments.html

Prepared by Dr. Jannat


SDET in Chemical Engineering

Lock and key mechanism

https://www.google.com/search?q=lock+%26+key+mechanism&rlz=1C1CHBD_enSG730SG730&sxsrf=APq-WBs2ZDRDqj0elbUuGobKkExHYpzdQg:1645623548451&source=lnms&tbm=isch&sa=X&ved=2ahUKEwiT5qe4-
ZX2AhWy4jgGHUSYCD4Q_AUoAXoECAEQAw&biw=1366&bih=657&dpr=1#imgrc=6pJ4iR0ke2b1WM
Prepared by Dr. Jannat
SDET in Chemical Engineering

Enzyme Inhibition
• Enzyme active sites are occupied by other substance than substrate
• It causes decrease in enzyme activity

Inhibitor

Substrate

Enzyme

https://www.goconqr.com/flashcard/12017048/enzyme-inhibition Prepared by Dr. Jannat


SDET in Chemical Engineering

Types of Enzyme Inhibition


• Competitive
• Non-competitive
• Un-competitive

https://www.researchgate.net/publication/319715362_Redox_Reactions_in_the_Physiopathology_of_the_Liver/figures?lo=1 Prepared by Dr. Jannat


SDET in Chemical Engineering

Enzyme Inhibition: Competitive

• Inhibitor competes with substrate to occupy the active site


• Increasing substrate concentration can overcome inhibition

Normal Competitive
Substrate Inhibitor

https://chem.libretexts.org/Courses/University_of_Arkansas_Little_Rock/Chem_4320/Chem_4320%2F%2F5320%3A_Biochemistry_1/05%3A_Michaelis-Menten_Enzyme_Kinetics/5.4%3A_Enzyme_Inhibition
Prepared by Dr. Jannat
SDET in Chemical Engineering

Enzyme Inhibition: Non-competitive

• Inhibitor binds with different active site or enzyme-substrate complex


• Increasing substrate concentration cannot overcome inhibition

Normal
Substrate

Non-competitive
Inhibitor

https://chem.libretexts.org/Courses/University_of_Arkansas_Little_Rock/Chem_4320/Chem_4320%2F%2F5320%3A_Biochemistry_1/05%3A_Michaelis-Menten_Enzyme_Kinetics/5.4%3A_Enzyme_Inhibition
Prepared by Dr. Jannat
SDET in Chemical Engineering

Enzyme Inhibition: Un-competitive

• Inhibitor binds with enzyme-substrate complex only


• Increasing substrate concentration favors inhibition

Enzyme- Un-competitive
Substrate Inhibitor
Complex

Prepared by Dr. Jannat

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy