Eamc Notes
Eamc Notes
DOSING FOR ANESTHETIC DRUGS IN OBESE § MRM – for periop pain management
LEAN BW ADJUSTED BW TOTAL BW o PEC 2
(males max 100kg, (Ideal +
o Serratus anterior block + PEC 1
females max 70kg) 40% excess)
§ Propofol § Propofol § Suxamethonium POSTERIOR PERIPHERAL BLOCK
induction infusion § LMWHs (titrate § TRANSVERSUS ABDOMINAL PLANE (TAP) BLOCK
§ Thiopental § Neostigmine dose with Xa o 1 = external oblique, internal, transversus abdominis
§ Fentanyl (max 5 mg) levels) 2 = aponeurosis (near quadratus 5umborum) (20 cc
§ Alfentanil § Antibiotics § Midazolam Bupivacaine)
§ Morphine § Sugammadex § Fentanyl/sufenta § The more posterior, the better
§ Rocuronium § Paracetamol? § Cistracurium § NPO patient = Bull’s eye sign
§ Cistacurium § LMWH? induction § Stomach – is above aorta
maintenance § Sugammadex
§ Paracetamol § Neostigmine § RECTUS ABDOMINIS BLOCK
§ Bupivacaine § Mivacurium o Inguinal hernia to ↓ MAC
§ Lidocaine o Start at the middle
o Insert needle at aponeurosis at far end between
PONV PROPHYLAXIS BASED ON APFEL SCORE external and transversus abdominis
Risk score Prevalence Prophylaxis § Darkest – transversus abdominis
0 9% ± Ondansetron 4 mg § Thickest – external abdominis
1 20% Ondansetron 4 mg
± Dexamethasone 4 mg § PARAVERTEBRAL BLOCK
2 39% Ondansetron 4 mg o Cover 1-2 levels above & 1-2 levels below
+ Dexamethasone 4 mg § ERRECTOR SPINAL BLOCK
± Propofol infusion o On top of the bone
3 60% Ondansetron 4 mg § *Indicator that the block is correct the lungs will go up
+ Dexamethasone 4 mg
+ Propofol infusion
± Scopolamine patch EPIDURAL TEST DOSE
4 78% Ondansetron 4 mg ü 9.5cc Lidocaine (ampule) + 0.5 cc cocktail (1 cc syringe: 0.1cc
+ Dexamethasone 4 mg epinephrine + 0.9cc lidocaine)
+ Propofol infusion ü Epinephrine: 1:200,000 dilution
+ Scopolamine patch ü Top up dosing (mg): from insertion site (L3-L4/C6-C7) to target
sensory block (L3-T4: 10mg)
SIMPLIFIED APFEL SCORE PONV RISK % 30-45 mg Lidocaine OR 5-10 mg Bupivacaine
§ Female = 1 point § 1 risk factor = 20% § (+) signs of subarachnoid anesthesia
§ Non-smoker = 1 § 2 risk factor = 40% o 2-3 mins: warmth or tingling sensation on legs/feet,
§ History of PONV = 1 § 3 risk factor = 60% sensory block to cold & pinprick, motor block
§ Post-operative opioids = 1 § 4 risk factor = 80% § 2 limitations of lidocaine in pregnant:
TOTAL: 0-4 o Warmth in legs and motor weakness after injection
o Extensive sensory and sympathetic block
o High subarachnoid block
LMA SIZE = WEIGHT
§ 1,2 = pedia Lidocaine + 15 mcg Epinephrine IV
§ 3 = 30-50 kg § (+): ↑HR by at least 10 bpm & SBP 15 mmHg
§ 4 = 50-70 kg § Seizure, cardiac arrest
§ Blunt these responses: sedation, general anesthesia, β-
§ 5 = 70-90 kg blockade, elderly, and pre-existing neuraxial block
§ PRESSURE: not more than 60
DLT (Ht) Laboring women
§ MALE: >140 cm = Fr. 41, <170 cm = Fr. 39 § Pain-induce tachycardia can confuse with + epinephrine
§ FEMALE: >160 cm = Fr 39, <160 = Fr 37 response
§ Bilateral sensory change & analgesia 20-30 mins after 10-15 Ml
ETT SIZES DEPTH
of dilute local anesthetics or dilute opioid
§ Pedia uncuffed: Age (yrs)/4 + 4 § Age + 10
§ >2 y/o cuffed: Age (yrs)/4 + 3.5 § Age/2 +12 Surgical patients
§ <2 y/o cuffed: Age (yrs)/4 + 3 § ETT size x 3 § 2-chloroprocaine/ Lidocaine: warmth and numbness 5 to 10
§ Adult Female: size 7-8 § 18-20 mins after
§ Male: size 8-9 § 20-22 § Bupivacaine/ Ropivacaine: 15 to 30 mins after
MAINTENANCE FLUID DIFFICULT MASK VENTILATION (MOANS)
SHORTCUT (24 hrs cycle) Mask seal inadequate
§ Wt (kg) + 40 Obesity/ Obstruction
HOLLIDAY-SEGAR Age >55
§ 1st 10 kg: 100 mL/kg No teeth
§ 2nd 10 kg: 50 mL/kg Stiff lungs/ Sleep apnea
§ Remaining kg: 20 mL/kg
FOR 24 HR CYCLE DIFFICULT LARYNGOSCOPY (LEMON)
§ 1st 10 kg: 4 mL/kg/24 hr = 40 Look externally: beard, small chin, buck teeth, facial trauma,
§ 2nd 10 kg: 2 mL/kg/24 hr = 20 airway bleeding
§ Remaining kg: 1 mL/kg/24 hr Evaluate 3-3-2:
FLUID DEFICIT § Inter-incisor <3
FD = [MF x NPO (hrs)] – [Input (IVF,BT) + Output (UO,edema)] § Mentohyoid <3
1st hr = FD/2 + MF § Thyrohyoid <2 fingerbreadths
2nd – 3rd hr = FD/4 + MF Mallampati score >3
4th hr = MF + Fluid loss stress Obesity/ Obstruction
Neck pathology (immobilization/surgery)
SPINAL COCKTAIL
§ 0.9 cc Bupivacaine + 0.1 cc Morphine DIFFICULT SUPRA GLOTTIC AIRWAY INSERTION
o 100 mcg/mL dilution (RODS)
o 2-3 drops Morphine Restricted mouth opening
o Usually 200-300 mcg/mL dilution Obstruction
Distorted anatomy (surgery/infection/trauma/tumor)
Stiff lungs
POST-OP CARE FOR OBESE
PACU discharge: DIFFICULT SURGICAL CRICOTHYROIDOTOMY (SHORT)
§ Discharge criteria met
Surgery to neck
§ SpO2 maintained at pre-op levels w/ minimal O2 therapy
§ No evidence of hypoventilation Hematoma to neck
OSA or Obesity Hypoventilation Syndrome: Obesity
§ Sit up and avoid sedatives and post op opioids Radiotherapy to neck
§ Reinstate patient’s own CPAP if applicable w/ additional Tumor
time in recovery until free of apneas w/o stimulation
§ Untreated, intolerant of CPAP or ineffectively treated EQUIPMENT FOR OBESE
(persistent symptoms) are at risk for hypoventilation § Suitable bed/trolley & OR table
§ IV opioids should be avoided, but if warranted, continue § Gel padding
SpO2 monitoring and level 2 care must be considered. § Wide strapping
§ Table extension/arm boards
§ Forearm cuff or large BP cuff
FACTORS ↑ MAC § Step for anesthetist
§ Acute use of amphetamine § Difficult airway equipment
§ Cocaine § Video laryngoscope
§ Ventilatory with PEEP & pressure modes
§ Ephedrine
§ Hover mattress
§ Chronic use of Ethanol § Long spinal, regional, and vascular needles
§ Highest at 6 months old § Ultrasound machine
§ Hypernatremia § Appropriately sized calf compression devices
§ Hyperthermia § Depth of anesthesia monitoring
§ Red hair § Neuromuscular monitoring
§ Sufficient staff to move the patient
FACTORS ↓ MAC § Ramping
§ Propofol o Tragus level with sternum
§ Etomidate o Reduces risk of difficult laryngoscopy
§ Barbiturates o Improves ventilation and pre-oxygenation
§ Benzodiazepine
§ Ketamine GENERAL GOOD WARD LEVEL PRACTICE
§ α2-Agonist (Clonidine, Dexmedetomidine) § Multimodal analgesia
§ Acute use of Ethanol § Caution with long-acting opioids and sedatives
§ Local anesthetics § Early mobilization
§ Opioids § Robust thromboprophylaxis regimen
§ Chronic use of amphetamine § Experienced consultant review
§ Lithium
§ Verapamil
THYROIDECTOMY
§ Elderly
§ Hyponatremia ü Vocal cord paralysis d/t accidental cut of recurrent
§ Anemia (Hgb <5 g/dL) laryngeal nerve
§ Hypercarbia ü Check vocal cord via laryngoscopy prior extubation
§ Hypothermia ü If with paralysis = can delay extubation
§ CNS hyperosmolality ü Repeat serum Calcium 6 hrs post specimen out
§ CNS depressants, Tranquilizers, Narcotics (indicate time)
§ Hypoxia
§ Pregnancy
INNERVATION OF THE LARYNX
NERVE SENSORY MOTOR PHYSIOLOGIC CHANGES OF PREGNANCY AT TERM
Internal superior § Epiglottis Plasma volume ↑ 40-50%
laryngeal nerve § Base of tongue Total blood volume ↑ 25-40%
§ Supraglottic Hemoglobin ↓ 11-12 g/dL
mucosa NONE Fibrinogen ↑ 100%
§ Thyroepiglottic Serum cholinesterase ↓ 20-30%
joint
Systemic vascular resistance ↓ 50%
§ Cricothyroid
joint Cardiac output ↑ 30-50%
External superior Anterior subglottic Cricothyroid Systemic blood pressure ↓ slight
laryngeal nerve mucosa membrane Functional residual capacity ↓ 20-30%
Recurrent § Subglottic § Thyroarytenoid Minute ventilation ↑ 50%
laryngeal mucosa membrane Alveolar ventilation ↑ 70%
§ Muscle § Lateral Oxygen consumption ↑ 20%
spindles cricoarytenoid Carbon dioxide production ↑ 35%
membrane Arterial carbon dioxide tension ↓ 10 mmHg
§ Interarytenoid Arterial oxygen tension ↑ 10 mmHg
membrane Minimum alveolar concentration ↓ 32-40%
§ Posterior
cricoarytenoid
membrane
PREOXYGENATION/ DENITROGENATION
ü 8 Vital capacity breaths / deep breaths of 100% oxygen
MEDS & ANESTHETIC IMPLICATIONS PRE-OP over 60 seconds
MEDS ANESTHETIC RECOMMENDATION o 4 vital capacity breaths of 100% oxygen over 30
AMINOGLYCOSIDES Potentiates non- Monitor NMBs carefully seconds = high arterial Pao2 (339mmHg)
depo relaxants ü Tidal volume breathing of 100% oxygen at 10-12 LPM via
CLONIDINE ↓anesthetic Continue on day of sx, tight fitting mask for 5 minutes
requirement; can use dermal periop
HTN crisis o Will give 8 mins apneic time before desaturation
o BOTH replaces 80% of FRC with oxygen
LITHIUM Potentiates Monitor NMBs & s. Na;
NMBs; induces avoid Na-wasting ü Sevoflurane
hypothyroidism diuretics; obtain thyroid o Low pungency
func tests o Rapid onset
MAO INHIBITORS ↑catecholamine Avoid indirect-acting & o High potency permitting delivery of high-inspired
stores; ↓direct-acting oxygen concentration
hepatotoxic sympathomimetics; do ü Priming
LFTs; Avoid Meperidine; o Filling the breathing circuit with 8% sevoflurane by
Discontinue 14-21 days
emptying the reservoir bag
for elective sx
o Open adjustable pressure-limiting valve
WARFARIN Excessive Withdraw in advance;
intraop bleeding substitute Heparin b/c it o Use high fresh gas flow (8L/min) for 1 min before
may stop immediately applying the face mask
preop & restarted o Can produce loss of consciousness for 1 minute
Somatostatin
§ 250 mg IV bolus then
o 3 mg in 250cc D5W x 12 hrs
o 3 mg in 500cc D5W x 42 hrs (250 mg/hr)
LAYERS TRAVERSING IN MEDIAL SPINAL ANESTHESIA § Acute angle of the right mainstem bronchus at the carina
Skin → subcutaneous fat → supraspinous/interspinous § Turbulent gas flow until the 5th bronchial division
ligament → ligamentum flavum → epidural space → dura (resistance is inversely related to the radius to the 5th
mater → subdural space → arachnoid mater → power)
subarachnoid space
INDICATION IN EPIDURAL SPACE
§ “snap” supraspinous ligament
§ “mushy” intraspinous ligament
§ “gritty” ligamentum flavum = pop