Peripheral Nerve Injuries
Peripheral Nerve Injuries
Peripheral nerve - A nerve belonging to the Peripheral Nervous System (PNS), a network of
43 pairs of motor and sensory nerves that connect the central nervous system (CNS, composed
of the brain & spinal cord) to the entire human body
● Peripheral nerves control the functions of sensation, movement and motor coordination
● Fragile and can be damaged easily
Causes: Peripheral nerves can sustain injury from a number of causes, including accidents or
trauma.
● Laceration (a cut or tear in the nerve tissue)
● Severe bruising (contusion)
● Gunshot wounds
● Stretching (traction)
● Drug injection injury
● Electrical injury
Symptoms
● Any of the following in the the affected area
○ Severe, unrelenting pain
○ Burning sensation
○ Tingling sensation
○ Numbness sensation
○ Total loss of sensation
Treatment:
● Treatment depends on:
○ Type of injury
○ Symptoms
○ The amount/severity of nerve injury sustained.
● For mild nerve injuries, the following non-surgical treatments may be part of the plan:
○ Acupuncture
○ Massage therapy
○ Medication
○ Orthotics
○ Physical/occupational therapy and rehabilitation (exercises, stretches, physical
agent modalities)
Classification
● 3 Basic Types of PNI:
1. Stretch related - Most common. The peripheral nerves are elastic, but when a
traction force is too strong, injury occurs. If the traction force is strong enough, a
complete tear may occur, but most commonly the continuity is retained, resulting
in injuries such as Erb's Palsy.
2. Lacerations - Type of injury in which the peripheral nerve is severed by a blade
→ Might be completely severed but usually some continuity remains.
3. Compressions - Type of injury caused by excessive pressure on a nerve via
nerve compression or entrapment
a. Does not involve tearing of the neural elements.
b. Certain nerves are more susceptible to this type of injury because of
where they are located in the body
c. Common entrapment neuropathies include:
i. Median nerve entrapment (“Carpal tunnel syndrome”)
ii. Radial nerve compression (“Saturday night palsy”)
iii. Anterior interosseous neuropathy
iv. Ulnar nerve entrapment
v. Femoral nerve entrapment
vi. Peroneal nerve entrapment
d. Some medical conditions may increase the likelihood of this injury, such
as diabetes, hypothyroidism, acromegaly, amyloidosis, carcinomatosis,
polymyalgia rheumatica, rheumatoid arthritis or gout.
● Sunderland classification system defines five different degrees of PNI:
1. First degree: A reversible local conduction block at the site of the injury. This
injury does not require surgical intervention and usually will recover within a
matter of hours to a few weeks.
2. Second degree: There is a loss of continuity of the axons (the “electrical wires”)
within the nerve. If this kind of injury can be confirmed through pre-operative
nerve testing, surgical intervention is usually not required.
3. Third degree: There is damage to the axons and their supporting structures
within the nerve. In this case, recovery is difficult to predict. Nerve conduction
studies performed during surgery are often able to help indicate outcome and
need for simple cleaning of the nerve (neurolysis) or a more extensive repair with
grafting.
4. Fourth degree: In this case, there is damage to the axons and the surrounding
tissues sufficient to create scarring that prevents nerve regeneration. Electrical
testing performed during surgery confirms that no electrical energy can be
passed along the neural pathways in this injured nerve. Surgical intervention with
nerve grafting is necessary to repair the injury.
5. Fifth degree: These injuries are usually found in laceration or severe stretch
injuries. The nerve is divided into two. The only way to repair a fifth-degree injury
is through surgery.
Medical Diagnosis
● In order to fully determine the extent of the damage to the nerve, the doctor may order
one of the following diagnostic tests:
○ An electrical conduction test to determine the passage of electrical currents
through the nerves.
■ Electromyography
■ Nerve conduction velocity
○ An imaging test such as:
■ CT scan
■ MRI
■ MRI neurograph
●
●
Ulnar Nerve
● Innervates Flexor Carpi Ulnaris muscle, Flexor Digitorum Profundus (ulnar head)
Median Nerve
● Arises from vertebral levels C6-T1 via the brachial plexus
● Courses along the brachial artery, travels down anterior department of arm
● At level of elbow: Lies between humeral, superficial, and ulnar deep heads of pronator
teres (big area of entrapment of median nerve)
● Enters anterior department of forearm into Flexor Digitorum Superficialis muscle
● At elbow and proximal aspect of forearm, innervates several muscles that are important
for hand function/typing/occupational reasons (Pronator Teres, Flexor Carpi Radialis,
Palmaris Longus, and Flexor Digitrum Superficialis)
● At the level of the humeral head of Pronator Teres, the anterior interosseous nerve
splits off from the median nerve. Named as such as it travels along the anterior
interosseous. Innervates deep muscles of the anterior forearm except ulnar half of FDP.
● Innervation:
○ Abductor Pollicis Brevis
○ Flexor carpi radialis
○ Flexor digitorum superficialis
○ Flexor pollicis brevis & longus
○ Lumbricals 1 & 2
○ Opponens pollicis
○ Palmaris Longus
○ Pronator quadratus
○ Pronator teres
○ Flexor digitorum profundus (radial half)
■ If you are trying to differentiate whether the issue is more myotomal
(relating to spinal root) vs distal nerve, assess finger flexion strength:
● Digits 2 and 3 flexion is caused by FDP innervated by MEDIAN N.
● Digits 4 and 5 flexion is caused by FDP innervated by ULNAR N.
THEREFORE
● Finger flexion weakness in Digits 2 & 3 = median n. dysfunction
● Finger flexion weakness in Digits 4 & 5 = ulnar n. dysfunction
● Finger flexion weakness in Digits 2-5 = dysfunction more
proximally, prior to split of median and ulnar nerves
● Popular areas of entrapment:
○ Pronator teres (elbow level)
○ Carpal tunnel (wrist level)
Radial Nerve
● Supplies the posterior portion of the upper limb
● Innervates the triceps brachii, brachialis, brachioradialis, and extensor carpi radialis
longus
● Dysfunction DIMINISHES ability to supinate, but since biceps brachii is the PRIMARY
muscle that supinates, person will still be able to supinate as long as biceps are intact
Arcade of Frohse
● The most superior part of the superficial layer of the supinator muscle
● A fibrous arch over the posterior interosseous nerve
● Sometimes called the supinator arch
SPECIFIC DIAGNOSES
a.
b. Characterized by:
i. Inflammation in the common extensor tendon (tendon origin of the
extensor carpi radialis brevis muscle)
ii. The focal point of pain most likely near the lateral epicondyle of humerus
c. Causes
i. Repetitive movement
d. Treatment
i. Rest. Avoid activities that aggravate your elbow pain.
ii. Pain relievers. Try over-the-counter pain relievers, such as ibuprofen
(Advil, Motrin IB) or naproxen (Aleve).
iii. Ice. Apply ice or a cold pack for 15 minutes three to four times a day.
iv. Technique. Make sure that you are using proper technique for your
activities and avoiding repetitive wrist motions.
3. Medial epicondylitis of “Golfer’s elbow”
a. Symptoms
i. Pain and tenderness usually felt on the inner side of the elbow. The pain
sometimes extends along the inner side of your forearm and is typically
exacerbated by certain movements.
ii. Stiffness - The elbow may feel stiff, and making a fist might hurt.
iii. Weakness - You may have weakness in your hands and wrists.
iv. Numbness or tingling - These sensations might radiate into one or more
fingers — usually the ring and little fingers.
b. Causes
i. Damage to the muscles and tendons that control the wrist and fingers,
typically related to excess or repeated stress — especially forceful wrist
and finger motions
ii. Improper lifting, throwing or hitting, as well as too little warmup or poor
conditioning during racket sports, throwing sports, or weight training
iii. Forceful, repetitive occupational movements. These occur in fields such
as construction, plumbing and carpentry
c. Prevention strategies:
i. Strengthen your forearm muscles. Use light weights or squeeze a tennis
ball. Even simple exercises can help your muscles absorb the energy of
sudden physical stress.
ii. Stretch before your activity. Walk or jog for a few minutes to warm up your
muscles. Then do gentle stretches before you begin your game.
iii. Fix your form. Whatever your sport, ask an instructor to check your form
to avoid overload on muscles.
iv. Use the right equipment. If you're using older golfing irons, consider
upgrading to lighter graphite clubs. If you play tennis, make sure your
racket fits you. A racket with a small grip or a heavy head may increase
the risk of elbow problems.
v. Lift properly. When lifting anything — including free weights — keep your
wrist rigid and stable to reduce the force to your elbow.
vi. Know when to rest. Try not to overuse your elbow. At the first sign of
elbow pain, take a break.
d. Therapy Interventions:
i. Rest. Put your golf game or other repetitive activities on hold until the pain
is gone. If you return to activity too soon, you can worsen your condition.
ii. Ice the affected area. Apply ice packs to your elbow for 15 to 20 minutes
at a time, three to four times a day for several days. To protect your skin,
wrap the ice packs in a thin towel. It might help to massage your inner
elbow with ice for five minutes at a time, two to three times a day.
iii. Use a brace. Your doctor might recommend that you wear a counterforce
brace to reduce tendon and muscle strain.
iv. Stretch and strengthen the affected area. Progressive loading of the
tendon with specific strength training exercises has been shown to be
especially effective.
v. Gradually return to your usual activities. When your pain is gone, practice
the arm motions of your sport or activity. Review your golf or tennis swing
with an instructor to ensure that your technique is correct, and make
adjustments if needed.
4. DeQuervain’s tenosynovitis
a. A painful condition affecting the tendons on the thumb side of your wrist.
b. Symptoms:
i. Pain when you turn your wrist, grasp anything or make a fist.
ii. Pain near the base of your thumb
iii. Swelling near the base of your thumb
iv. Difficulty moving your thumb and wrist when you're doing something that
involves grasping or pinching
v. A "sticking" or "stop-and-go" sensation in your thumb when moving it
vi. If the condition goes too long without treatment, the pain may spread
further into your thumb, back into your forearm or both. Pinching, grasping
and other movements of your thumb and wrist aggravate the pain.
c. Causes:
i. The exact cause is unknown
ii. Exacerbated by repetitive hand or wrist movement — such as working in
the garden, playing golf or racket sports, or lifting your baby. (Repeating
a particular motion day after day may irritate the carpal tunnel, causing
thickening and swelling that restricts their movement.)
iii. Direct injury to your wrist or tendon; scar tissue can restrict movement of
the tendons
iv. Inflammatory arthritis, such as rheumatoid arthritis
d. Diagnosis
i. Examine the hand - Does the patient report pain when pressure is applied
to the thumb side of the wrist?
ii. Finkelstein test - Test in which you bend your thumb across the palm of
your hand and bend your fingers down over your thumb. Then you bend
your wrist toward your little finger. If this causes pain on the thumb side of
your wrist, you likely have de Quervain's tenosynovitis.
g.
h. Treated with outpatient surgery to decompress the median nerve by cutting the
ligament at the bottom of the wrist to release pressure. Your hand and wrist may
be bandaged for seven to 10 days. Often the bandage stays in place until you
visit the clinic for removal of the stiches. You may or may not experience
immediate relief, as the area will be sore following surgery. That will improve over
time. Pain medication will be provided before you go home. It is recommended
that you rest and elevate your hand and wrist, as well as limiting their use.
i.
PT/OT Assessments
● Must assess where sensory symptoms are reported → Location of sensory symptoms
will match dermatomes of specific nerve
● If you are trying to differentiate whether the issue is more myotomal (relating to spinal
root) versus distal nerve, we can assess finger flexion strength
● Tinel Sign & Phalen Sign YouTube video
● Assess which digits display weakness:
○ Weakness in Digits 2 & 3 finger flexion = stemming from MEDIAN NERVE
○ Weakness in Digits 4 & 5 finger flexion = stemming from ULNAR NERVE
○ Weakness in ALL digits or digits 2-4 = stemming from NERVE ROOT
Interventions
● Most treatment of peripheral nerve problems are geared to reduce or eliminate
symptoms.
● Nonsurgical treatments include medications, immobilization and physical therapy
● Surgical treatment may be needed if the individual has persistent neurologic symptoms
or if conservative therapies have been unsuccessful.
Physical Agent Modalities (PAMs): If the underlying reasons for the decreased ROM are scar
tissue or pain, PAMs such as US or heat (hot pack, parrafin bath) may be indicated
● Should be used as an ADJUNCT to therapy → NOT the sole intervention
● Examples (W&S) P.664
○ Superficial heat (hot packs, heating pads, paraffin wax, fluidotherapy, whirlpool)
■ Indiciations:
● Prior to active exercise, passive stretching, and joint mobilization
● Before traction and soft tissue mobilization
● Reduce joint pain and muscle spasms
● AFTER acute inflammation to promote tissue healing via cellular
activity
■ Contraindications
● Decreased circulation
● Decreased sensibility
● Open wounds or recently healed burns
● Signfiicant areas of edema
● Over tissue during acute inflammation
○ Deep heat US
■ Indiciations:
● Soft tissue tightness
● Subacute and chronic inflammation (i.e. tendinitis)
● Bone fracture
● Wound healing
■ Contraindications
● Do not use over or near eyes or ears
● Do not use near heart
● Do not use near pregnant uterus
● Do not use near testes,
● Do not use near known or expected malignant tumor
● Do not use near pacemaker
● Do not use near joint replacements, metal implants, insensate
areas
○ Therapeutic Cold (cold packs, cold baths, & ice massage)
■ Indiciations:
● Minimize acute inflammation
● Reduce edem & bleeding
● Reduce spasticity
■ Contraindications
● Temperature sensation deficits
● Circulation deficits
● Altered cardiorespiratory status
● Cold hypersensitivity such as Raynaud’s phenomenon
■ Evidence for Effectiveness
○ Contrast baths
■ Indiciations:
● Promotes tissue healing
■ Contraindications:
● PVD
● Loss of sensation
● Pregnancy
● Cold hypersensitivity such as Raynaud’s phenomenon
■ Precautions:
● Cardiovascular problems such as fluctuations in BP may occur
■ Evidence for Effectiveness
○ Electrotherapy iontophoresis
■ Indiciations:
● Modulate pain
● Decrease inflammation (i.e. bursitis, tendinitis)
● Reduce edema
■ Contraindications
● Do not use over eyes or ears
● Do not use over chest of person with cardiovascular disease
● Do not use over pregnant uterus
● Do not use over wounds or skin breaks
● Do not use over known or expected malignant tumor
● Do not use over pacemaker
● Do not use over blood vessels susceptible to hemorrhage,
thrombus, or embolus
● Do not use over insensate areas
■ Evidence for Effectiveness
Splints - “Splints and orthotics are external devices that are applies to the body to immobilize,
restrain, or support injured tissues; align or correct deformities; and improve function (Anderson,
Anderson, & Ganze, 1998; O’Toole, 1997). W&S p.663
● May be used to:
○ Support healing
○ Reduce stress on joints such as wrist support splints for CTS and arthritis pain.
Thumb splints may be indicated for CMC arthritis or deQuervain’s tendinitis
○ Align or correct deformities, for example ulnar deviation splints can be used for
clients with RA
● Examples
○ Wrist Cock-up
■ Carpal tunnel syndrome
■ Radial nerve palsy
■ Tenosynovitis/tendinitis
■ Wrist fractures
■ RA
■ OA
■ Reflex sympathetic dystrophy (RSD)
○ Resting splint
■ RA
■ Traumatic injuries: crush, contusion
■ Burns
■ Tendon injuries
■ Stroke
■ SCI
■ CNS disease & injury
■ Post-op dupuytrens
■ Infections
○ Thumb spica splint
■ DeQuervain’s syndrome
■ Degenerative arthritis / basilar joint arthritis
■ RA
■ Thumb sprains
■ Median nerve injuries
HEPs
● Must consider COMPLIANCE --. Therapists should make sure clients and families
understand the exercises and should provide them with written or picture instructions.
● ROM
○ Full ROM is typically not achieved during everyday tasks; therefore, individuals
who have ROM deficits may need passive, active assistive, or active ROM
exercises.
○ For a person who has undergone surgery or has been in a cast because of a
fracture, the decrease in joint motion is due to temporary immobilization and is
probably amenable to change. For this person, a more aggressive therapy using
a PAM (i.e. hot pack) along with activities or exercise would be indicated to
improve motion
Compensatory Strategies
● “Other compensatory approaches to treat strength and endurance impairments might
consist of using lighter-weight tools, using electric appliances, and client education
regarding joint protection, energy conservation, and work simplification
● Posture
a. Rounded shoulders / stooped posture causes shortening of anterior muscles.
Tight pectoralis and scalenes muscles can cause pressure on brachial plexus.
● Joint Protection principles (W&S p.668)
a. Respect pain - If pain persists for >2 hr after performing an activity, modify it by
spending less time on it, using adaptive equipment, or resting during an activity
b. Use proper body mechanics and use joints in good alignment
■ Lean forward to put weight over feet and use armrests on chairs to come
to standing position
■ Use the palms of your hands on the armrests to push up to standing
■ Push or pull on objects rather than lifting
■ Avoid bending, reaching, and twisting.
c. Avoid holding one position for a long time and prolonged repetitive motions
■ Alternate sitting & standing during an activity, or shift around
■ Relax & stretch the hands every 5 minutes when doing an activity that
requires holding objects or tools such as holding cards, pencils,
telephone, knitting or crochet needles, garden, kitchen, or hand tools
■ Avoid kneeling to scrub the floor or to garden; instead, sit on a stool and
use longer-handled tools
d. Avoid positions and stress that cause deformity
■ Avoid pressures along the lateral (thumb) side of the fingers that
encourage ulnar deviation such as turning keys, doorknobs, or
screwdrivers
■ Avoid pressure against the back of the fingers and wrist, such as propping
the chin on the back of the hand
■ Avoid excessive and constant pressure against the pad of the thumb
■ Avoid positions of ulnar deviation of the wrist, such as cutting with
scissors or cutting with knives
e. Use the larger and strongest muscles & joints
■ Carry a briefcase or purse over one or both shoulders instead of holding it
with the fingers
■ Use the palm of the hands to lift pots and pans, or slide them along the
counter/table
■ Lift objects using your legs instead of your back muscles
f. Balance rest & activity
■ Exercise & activity are important for joint mobility & strength, but leisure
and work should be balanced with periods of rest
g. Never begin an activity that cannot be stopped immediately if needed.
■ Preplan and pace activities
■ Try to slide, push, or pull objects rather than lifting
● Energy Conservation strategies
a. Plan ahead
■ Gather all items needed before an activity
■ Spread heavy/strenuous and light tasks throughout the day/week rather
than scheduling heavy tasks back to back
■ Schedule more energy-demanding tasks earlier in the day
■ Schedule small rest breaks into your day
b. Pace yourself
■ Build in frequent small rest breaks before, during, and after each task
■ Break activities into smaller units that can be done over a number of days
■ Pace yourself while doing activities - do not rush
c. Prioritize
■ Decide which activities are important to be completed and ones that can
be completed later or eliminated
■ Delegate tasks to other family members of friends
d. Use efficient positioning
■ Sit when possible (use a seat in the shower instead of standing, sit on the
bed or a chair to get dressed, consider a high stool to sit on while doing
dishes)
■ Maintain good posture
● Avoid a prolonged stooped posture
● Avoid excessive reaching and bending by pre-arranging work
centers to be an appropriate height and keeping frequently-used
items at comfortable heights
e. Use work simplification techniques
■ Eliminate unnecessary tasks (i.e. buy permanent-press clothes, precut
vegetables)
■ Work in a well-lit, ventilated environment