Vitamins
Vitamins
VITAMINS:
Composition and Sources:
Szent Gyogi says that, a vitamin is something that makes us sick when we do not eat it. Vitamins
are defined as, potent organic compounds, occurring in varying and minute proportions in food,
which must be available to the organism from exogenous sources, in order that physiological
processes essential to life may proceed normally.
Vitamins are natural substances found in plants and animals and known as Essential nutrients for
human beings. Dr. Funk introduced the term vitamine for these organic compounds. The vitamin
which Funk extracted contained as amine and that is found to be essential for vital activities.
Hence the name Vitamine. But later it was found that amine was not present in all the vitamins.
Hence ‘e’ was deleted and the term Vitamin was used instead of Vitamine.
Vitamins are low molecular weight organic compounds indispensable for the normal vital activity
of the organisms. Their absence causes deficiency diseases.
Vitamins either participate in the production of coenzymes, indispensable for normal functioning
or the corresponding enzymes or act as regulators or biochemical processes.
Sources of Vitamins:
Plants synthesize all vitamins, animals cannot synthesize all vitamins. But vitamins are present in
animals as a result of food intake. In humans the vitamin sources are food and intestinal bacteria.
Human body uses these substances to stay healthy and support its many functions.
The body needs vitamins to stay healthy and a varied diet usually gives you all the vitamins you
need. Vitamins do not provide energy (calories) directly, but they do help regulate energy-
producing processes.
There are two types of Vitamins –
i) Fat soluble vitamins such as Vit. A, D, E and K.
ii) Water soluble vitamins such as Vit. B1, Riboflavin, Vit. B6, Niacin, Panthothenic acid, Folic
acid, Vit. C etc.
Vitamin D properties
Good for Strong bones and teeth
Signs of deficiency Unhealthy teeth, osteomalacia (causes weakening of bones), rickets in children.
RDA 5 micrograms
Good sources Sunlight (the action of sunlight on the skin allows our bodies to
manufacture vitamin D), cod liver oil, sardines, herring, salmon, tuna, milk and
milk products.
Poisoning This vitamin is fat-soluble so can accumulate in the body. Overdoses are
dangerous, but there is wide variability in the toxic level, eg 400IU for
children.
Destroyed by Mineral oil.
Vitamin E (Tocopherol) properties
Good for Fighting toxins – vitamin E is a powerful antioxidant.
Signs of deficiency Weak muscles and fertility problems
RDA 10 mg
Good sources Nuts, soya beans, vegetable oil, broccoli, sprouts, spinach, wholemeal products
and eggs
Poisoning Potential effect with warfarin increasing risk of bleeding, more than 400IU/day
can increase risk of heart failure and death in long term illness.
Destroyed by Heat, oxygen, frost, iron and chlorine
Folic acid properties
Good for Production of red blood cells. It is essential in the first three months of
pregnancy to prevent birth defects such as spina bifida, cleft palate or cleft lip.
Signs of deficiency Tiredness due to anaemia and red tongue
RDA 200 micrograms. Women planning to conceive should take a daily supplement
of 400 mcg, continued for the first 12 weeks of pregnancy
Good sources Carrots, yeast, liver, egg, yolks, melon, apricots, pumpkin, avocado, beans, rye
and whole wheat and green leafy vegetables
Poisoning No danger. It dissolves in water, so any excess is passed in urine
Destroyed by Water, sunlight and heat
List of Vitamins with Chemical name, Food source, Recommended dietary allowances
(RDA), Deficiency disease and Overdose disease:
Name Chemical name of Food Source RDA Male: Deficiency Overdose disease
of Vitamin Age 19-70) disease
Vitamin
Fat Soluble Vitamins:
Vitamin Retinol, retinal and Cod liver oil 900 ug Night-blindness, Hypervitaminosis A
A four carotenoids Hyperkeratosis,
including beta and
carotene Keratomalacia
Vitamin Cholecalciferol Cod liver oil 5 – 10 ug Rickets and Hypervitaminosis D
D Osteomalacia
P a g e | 45
Functions of Vitamins:
Vitamins promote normal growth, provide proper metabolism, ensure good health and protect
against certain diseases. Vitamin is required by the body in small amounts for metabolism, to
protect health and for proper growth in children. Vitamins assist in the formation of hormones,
blood cells, nervous-system chemicals, and genetic material. Vitamins mainly serve as catalysts
for certain reactions in the body. They combine with proteins to create metabolically active
enzymes that in turn produce hundreds of important chemical reactions throughout the body. The
fundamentals of cells depend greatly upon vitamins. Vitamins are responsible for keeping cells
strong, binding tissues, fighting infections, etc. Without vitamins our cells would not function
properly and thus our organs would suffer and eventually we would no longer be able to survive.
Vitamins help regulate metabolism, help convert fat and carbohydrates into energy, and assist in
forming bone and tissue.
i) Vitamin A plays an important role in vision, bone growth, reproduction, cell division and
differentiation.
ii) Vitamin B complex improves the body's resistance to stress. Aids in digestion, promotes good
muscle tone, healthy skin. Vitamin B complex reduces muscle spasms, leg cramps, hand
numbness and helps regulate blood pressure.
iii) Vitamin C is responsible for helping to build and maintain our tissues and strengthening our
immune system.
iv) Adequate amounts of vitamin D is necessary for preventing bone loss.
v) Vitamin E is the most effective, fat-soluble antioxidant known to occur in the human body.
The main function of vitamin E is to maintain the integrity of the body's intracellular
membrane by protecting its physical stability and providing a defense line against tissue
damage caused by oxidation. Alpha-lipoic acid helps to neutralize the effects of free radicals
on the body.
vi) Vitamin K plays an important role in blood clotting and bone metabolism (carboxylation of
osteocalcin). Bioflavonoids have antioxidant, anti-inflammatory, antiallergenic, antiviral, and
anti-carcinogenic properties.
Vitamins as accessory factor of food:
In 1906, English biochemist Sir F. G. Hopkins was first called vitamin as accessory factor of
food. Because he was found that, most foods contain besides carbohydrates, proteins, fats,
minerals and water, other substances necessary for health.
Vitamin is a group of organic substances that are required in the diet of humans and animals for
normal growth, maintenance of life and normal reproduction. Vitamins act as catalysts; very often
either the vitamins themselves are coenzymes or they form integral parts of coenzymes. A
P a g e | 47
substance that functions as a vitamin for one species does not necessarily function as a vitamin for
another species. The vitamins differ in structure and there is no chemical grouping common to
them all.
Vitamins have diverse biochemical functions. Some have hormone-like functions as regulators of
mineral metabolism such as vitamin D or regulators of cell and tissue growth and differentiation
such as some forms of vitamin A. Others function as antioxidants e.g., vitamin E and
sometimes vitamin C. The large number of vitamins, such as B complex vitamins functions as
precursors for enzyme cofactors, which help enzymes in their work as catalysts in metabolism. In
this role, vitamins may be tightly bound to enzymes as part of prosthetic groups, for e.g. biotin is
part of enzymes involved in making fatty acids.
Vitamins may also be less tightly bound to enzyme catalysts as coenzymes, detachable molecules
that function to carry chemical groups or electrons between molecules, for e.g. folic acid may
carry methyl, formyl and methylene groups in the cell. Although these roles in assisting enzyme-
substrate reactions are vitamins best-known function, the other vitamin functions are equally
important.
Note : The recommended amounts of these vitamins are listed in three different ways: grams,
milligrams and micrograms.
Vitamin Examples of Function Recommended Upper Limit (The
Good Food Daily Amount Highest Amount
Sources (RDA) or Adequate You Can Take
Without Risk
Vitamin A Sweet potato Necessary for Men: 900 ug/day 3,000 ug/day
with peel, normal vision, Women: 700 ug/day
carrots, spinach, immune function,
fortified cereals reproduction
Vitamin Whole grain, Allows the body to Men: 1.2 mg/day Unknown
B1(Thiamin) enriched, process Women: 1.1 mg/day
fortified carbohydrates and Pregnant and
products; bread; some protein. breastfeeding
cereals women: 1.4 mg/day
Vitamin B2 Milk, bread Key in metabolism Men: 1.3 mg/day Unknown
(Riboflavin) products, and the conversion Women: 1.1 mg/day
fortified cereals of food into Pregnant Women:
energy; helps 1.4 mg/day
produce red blood Breastfeeding
cells Women: 1.6 mg/day
Vitamin B3 Meat, fish, Assists in Men: 16 mg/day For niacin in natural
(Niacin) poultry, enriched digestion and the Women: 14 mg/day sources, there is no
and whole grain conversion of food Pregnant upper limit.
breads, fortified into energy; Women: 18 mg/day For niacin in
cereals important in the Breastfeeding supplements or
P a g e | 48