RIFT VALLEY UNIVERSITY ADAMA CAMPUS COC ASSESMENT FOR LEVEL IV

PHARMACY TVET STUDENTS

1. In a prescription, RX MEANS:
A. Dispense C. Sale
B. Take D. Administer
2. Identify the dosage form which require shaking prior to usage
A. Emulsion C. Elixir
B. Syrup D. Tincture
3. Identify the vitamin which prevents bleeding.
A. Vitamin K C. Vitamin E
B. Vitamin D D. Vitamin A
4. The best ways to determine the storage conditions for a particular drug is to:
A. Refer to the united states C. Ask the pharmacist
pharmacopeia D. Try different ways of storage
B. Refer to the manufacturer`s label
5. Which drug must be taken 30 minutes before meal?
A. Omeprazole C. Amoxicillin
B. Cimetidine D. Diclofenac
6. which one of the Ethiopian TM bonesetters
A. debtera B. Wagesha C. weqaby D. kalicha
7. if 400,000 IU of procaine penicillin given daily for 07 days. how much vial is given ?
A. 3 vial B. vial C. 1 vial D. 0.5 vial
8. which one of the following drugs is used to type I diabetes not used for type II Diabetes
A. Metformin B. Glibenclamide C. Insuline D. Dailol
9. Drugs which have a potentially of life saving, are categorized as:
A. Vital C. less essential
B. Essential D. None essential
10. One which of the following area patient needs drug information from pharmacy professions?
A. Amount to be taken C. Duration of therapy
B. Frequency of administration D. All of the above
11. One of the following prescription information is used adjustment of the dose the drug.
A. Sex B. Age C. address D. diagnosis
12. Which of the following drug is different from the others?
A. Erythromycin B. Larothromycin C. Paramomycin D. Azithromycin
13. Which one has non phototoxicity effect?
A. Doxycyclin B. Ciprofloxacin C. Norfloxacin D. None
14. ____Causes gray baby syndrome
A. Vancomycine B. Chloramphenicol C. Gentamycin D. Erythromycin
15. Which one of the following is the principal drug metabolizing organ
A. Kidney B. Lung C. Liver D. Intestine
16. A 10 years old boy (weight is 30kg) has been prescribed Rifampicin 150mg tablet at a dose 10mg/kg
twice daily for 4 weeks. How many tablets should be dispensed for this patient to cover for 4 week.
A. 114 tablet B. 116 tablet C. 112 tablet D. 108 tablet
17. Substance like Glycerol and Sorbitol are commonly included in Capsule shell production. What is the
importance of these substance?
A. Increase stability B. Increase flexibility C. as preservatives
18. A 29 years old man was newly diagnosed with TB last week & started taking medication. He come
yesterday complaining orange-red discoloration of urine. Which of ant TB drug would be the cause for
discoloration of Urine.
A. Isoniazide B. Pyrazinamide C. Ethambutol D. Rifampicin
19. A patient with HIV AIDS has been taking a drug regimen ZDV/3TC/LPV it for last one year when the
patient come to ART clinic he/she diagnosed for Severe anaemia which drug would be the cause of
this side effects?
A. Lopinavir B. Lamivudine C. Zidovudine D. None
20. Alcohol of 70% needed for anti-fungi solution preparation but in you lab you have 50% and 75%
alcohol respectively mixed to prepare 120ml of 70%. Calculate the ratio used?
A. 3:2 B. 1:4 C. 7:5 D. 3:4 E. None
21. A patient was diagnosed for PUD due to H. pyroli the physician prescribes the following drug
regimen, Amoxacillin + Omeprazole + Clarithromycin. What is the role of Omeprazole?
A. Killing the H.pyroli B. Neutralizing the HCL C. Inhibit HCL secretion D. None
22. A hospital planned to procure pharmaceutical but there was no sufficient time. There was only one
supplier. Which method of procurement would be best option?
A. Competitive negotiation B. Open tender C. Restricted tender D. Direct procurement
23. A pregnant mother in her 1st trimester was diagnosed with uncomplicated plasmodium falciparum.
Which one is the best drug to be dispensed for this mother?
A. Chloroquine B. Quinine C. Primaquine D. Coatum
24. Which of the following Solution dosage form has Alcohol?
A. Spirit B. Enema C. Syrup D. Douche
25. Which is the most widely used Surfactant in the preparation of Suspension?
A. Sodium lauryl sulfate B. Poly sorbate 80 C. Methyl cellulose D. Tragacanth
26. One of the following alternative medicine involves penetrating the skin with thin solid metallic needs
that are manipulated by hands or electrical stimulation.
A. Ayurveda B. Acupuncture C. Chiro practice D. Aromatherapy
27. One of the following is Not the desired feature of Good Suspensions
A. Easy to pour B. Re-suspended C. Good syringe ability D. settle rapidly
28. Which of the following physical instability of Emulsion refers to a change in W/O to O/W or vise
versa.
A. Creaming B. Breaking C. Phase inversion D. Coalescence
29. One of the following statement is true about sedimentation property of Suspension
A. Deflocculated suspension will have clear supernatant on short period of standing
B. Flocculated suspension will produce cake on long period of standing
C. Flocculated suspension will form a porous sediment
D. The sedimentation volume of flocculated suspension is narrow
30. A physician prescribed CAF oral suspension for patient to be taken 10ml 4 times a day for 15 days. If
the concentration of this suspension 50mg/ml. how many milligram of the drug will patient receives in
15 days.
A. 2000mg B. 3000mg C. 10000mg D. 30000mg

31. A patient you are treating in the hospital has a Hypertension emergency. With pressure of
210/140mmhg. Which of the following drugs be the most effective intravenously?
A. Hydrochlorothiazide B. Methyl dopa C. Spirilactone D. Hydralaine
32. How many grams of Salicylic acid and Benzoic acid should be used in preparation of 100mg of an
Ointment containing 12% and 6% of each respectively.
A. 12mg & 6mg B. 22mg & 16mg C. 12mg & 9mg D. 6mg & 12mg
33. A topical agent that is frequently successful in Melasma.
A. Benzoic acid B. Hydroquinolone C. Calamine D. Beceplemine
34. According to WHO selection of drug based on all Except
A. Relevance to the pattern of prevalent C. Proven efficacy & safety
diseases
D. Favourable cost-benefit ration
B. Presence of d/f brand
35. An adverse effects associated with pharmacotherapy using Heparin
A. An increase in number of circulating C. Purple toe syndrome
platelets
D. Teratogenicity to the Foetus
B. Thrombocytopenia
36. Local anaesthetic interfere with the movement of ___________
A. Calcium B. Potassium C. Sodium D. Oxygen
37. Which of the following Opioid analgesically active mechanism?
A. Naloxone B. Codein C. Propoxyphene D. Meperidine
38. Drug that penetrate in blood brain barrier in reasonable concentration
A. Ampicillin B. Penicillin G C. Neomycin D. Cefotaxime
39. All of them act by inhibition of bacterial cell wall synthesis Except
A. Penicillin B. Vancomycin C. Cephalosporins D. Aminoglycosides
40. Drug administered orally if even fully absorbed into blood stream b/c of varies barrier Except
A. Biological barrier B. Physical C. Chemical D. Presence of Saliva
41. A pharmacy technician accidentally dropped half the medication from the bottle contained 20tsp of
pediatric cough syrup. How many ½tsp of doses in the bottle?
A. 16 B. 20 C. 40 D. 25
42. Gastric acid secretion is stimulated by the presence of
A. Histamine & motilin B. Norepinephrine & pepsin C. Ach & gastrin D. Ach & pepsin
43. Inventory management is the Heart of drug supply system. So poor inventory management leads to:-
Except
A. Wastage of financial resources
B. Good for patient needs for large quantity of drug
C. Shortage of essential drug
D. Decrease in the quantity of patient care
44. Drug of choice for inducing Labour
A. Misoprostol B. Ergometrine C. Mifeprostone D. Oxytoxin
45. Which one of the following drug are not used for treatment of glaucoma
A. Bexalol B. Timolol C. Pilocarpine D. Atropine
46. Which of the following is false about drug selection
A. Selection by generic name of the drug C. Cost effectiveness
B. Give priority for local manufacture D. Select by brand name of the drug
47. A patient prescribed to take prendisolone 80mg bid for 5 days the 40mg for 10 days, then 20mg QD
for 21 days. Prendisolone is available as 5mg enteric coated tablet. How many tablet of prendisolone
shoud be dispended?
A. 324 B. 424 C.144 D. 244

48. From the following given formula what is the concentration of salicylic acid in the ointment in %
W/W
Salicylic acid ------ 60gm
Benzoic acid ------- 40 gm
Vaseline ------------ 200 gm
A. 20% B. 13.3% C. 66.7% D. None
49. Which drug, when used in conjugation with amoxicillin would enhance the anti-bacterial action of this
drug
A. Capholosporin C. Vitamin B6
B. Clavulic acid D. Tetracycillin
50. _________ is a process in which the excess of standard solution used to react with analyte determined
by titration with the second standard solution
A. Direct titration C. Back titration
B. Blank determination D. Complex metric titration
51. Which one of the following drug is contraindicated in paediatric patients
A. Ethambutol C. Tetracycline
D. Glucocorticoid
B. Norfloxocillin E. All

52. How many milliliters of a medicine would provide a patient with 2 TSP twice a day for 15 days
 A. 200ml D. 150ml
B. 300ml E. None
C. 100ml
53. The following information should be recorded on prescription except
A. Prescription number C. Product & quantity dispensed
B. Expiration date D. Patient information
54. Which of the following vitamins should be avoided by a patient taking oral anti-coagulant
A. Vitamin A C. Vitamin K
D. Vitamin C
B. Vitamin B

55. Mr X UTI, with penicillin allergic . Which is the drug of choice.

A. Ampicillin C. Pipracillin
B. Amoxicillin D. Erythromycin.
56. Which drugs not store under 20c- 80c in refrigerator
A. Ergometr in D. Oxytoxian
B. Ergometrin E. None
C. TAT
57. Which of the following drugs is a protenase inhibitors
A. Lamavudine C. Ritonavir
B. Tenofovir D. Didonisine
58. Which one of the following disease not caused by protozoa
A. Ameobiasis B. Candiasis C.Giardiasis D. Malaria
59. Which one additive or excipeint added for the purpose of increasing production bulkiness of product.
A. Binders C. Anti-adherent
B. Diluents D. Lubricant

60. True about narcotic and psychotropic prescriptions

A. Can be prescribed by any doctor
B. Photo copied prescriptions can be dispensed
C. The prescription should not be dispensed after 15 days elapsed
D. More than one drug can be dispensed on a single prescription
61. Which of the following quantification method is used for estimation drug requirement in emergency
relief situations like cholera epidemic, floods etc
A. Adjusted consumption method B. Consumption method
C. Morbidity method D. One of the above
62. Which of the following method do you use to issue products from your medical store if the products
have the same expiry date but differ price.
A. FEFO C. LIFO
B. FIFO D. All
63. The basic technique in compounding of powders in sequential order is
A. Size reduction, weighing, mixing C. Weighing, mixing, size reduction
B. Mixing, size reduction, weighing D. Weighing, size reduction mixing
64. Choose the corrected matched
A. HCT- DM C. Metformin – Asthma
B. Metronidazole – Anti TB D. Enalapril – Antihypertensive
65. Which of the following alternative medicine practice in Chinese medicine
A. Acupuncture C. Unani
B. Homeopathy D. Ayurveda
66. The most widely used and convenient sterilization method
A. Chemical sterilization C. Dry heat sterilization
B. Mechanical sterilization D. Moist heat sterilization
67. Which one of the following is best method of extraction used for thermo labile plant constituent.
A. Soxhletion C. Reflex
B. Percolation D. Decoction
68. From 30% of 5ml H2 O2 prepared 5% H2 O2 how much ml of solvents (water) you use
A. 45ml C. 50ml
B. 30ml D. None
69. Which one of the following is an antiseptic alcohol.
A. Ethanol 70% C. Ethanol 98%
D. none
B. Ethanol 60%

70. Which one of the following formulation indicate dosage form containing drug substance dissolved in
the solvent.
A. Suspension C. Emulsion
D. Solution
B. Emulsion
71. Sister Alemitu Want to order DNS for emergency word. Which form should she used
A. Model 2021 C. Model 22
B. Model 19 D. Stock card.

72. Hydro carbon ointment base is characterized by

A. Have emollient effect B. Difficult to wash
C. Remain on skin for long period time D. All

73. The interaction b/n TTC and antacid is

A. At the level of excretion C. At level of excretion
D. At level of distribution
B. At the level of absorption

74. Alcohol + diazepam the effect is known as

A. Summative or additive C. Antagonist
B. Synergestic D. Potency.

75. The time at which the drug retains its stability, safety, efficacy and potency is known as
A. Shelf life C. Dispensing date
B. Manufacturing date D. Expiry date

76. Which one of the following indicate the first cycle on drug and medical supply management
A. Procurement C. Selection
B. Distribution D. Quantification
77. Which one of the following is not the base for drug selection and quantification
A. The prevalent health problem C. Quality and safety of the drug
B. The financial violability D. None
78. Which one of the following sources of drug information is classified under primary sources?
A .Ethiopian pharmaceutical C. Medical dictionary
joumal
D. Standard treatment
B .Hospital formulary guidelines
79. Which one of the following is the principal drug metabolizing organ
A. Kidney B. Lung C. Liver D. Intestine
80. Which procurement method leads to high price & quick
A. Restricted tender C. Competitive negotiation
B. Direct D. Open tender.

81. One of the following is not inhalation general anaesthetic.

A. Ether C. Ketamine
B. Nitrous oxide D. Halothane
82. Which of the following therapeutic uses of steroids.
A. For asthma D. For ophthalmic inflammation
B. Cough suppressant E. All except B
C. For rheumatoid arthritis

83. One of the following antibiotic cause aplastic anaemia.

 A. Streptomycin C. Cotrimoxozole
B. Amoxicillin D. Chlorphenicol(CAF)
84. Is ART drug prevent mother to child HIV transmission
A. Efevirenz C. Nevirapine
B. Stavudine D. Didonisine
85. One of the following drug is narcotic drugs
A. Phenytoin C. Lidocaine
B. Librax D. Pethidine

MATCHING
A
1. Ingredient information other than drug substance
2. Date that the first step of manufacture is perform
3. Capacity of drug product maintain its strength quality & purity throughout its shelf life
4. A substance with pharmacological effect
5. Any component present in the quality or API that is not desired quantity
6. Concentration of drug substances
7. A document specifying ingredient with their quantities compounding
8. A date which manufacturer no longer guarantees efficacy, safety &stability of drug product
9. 15-25oc
10. 2 oc-8 oc
11. 8 oc-15
12. Kept with item
13. Report & request for dispensing unit
14. Amount of drug taken (administered once
15. Available stock if any point in time

“ B”
A. Active ingredient H. Cold place O. Strength
B. Excipient I. Stock on hand P. RRF
C. IFRR J. Expiry date Q. Dose
D. Stability K. Manufacturing drug R. Room temperature
E. Cool place L. Impurity S. Bin card
F. Master formula M. Stock card
G. Shelf life N. Safety stock T. Purity

DRUG ARRENGMENT
Instruction: Demonstrate Arrangement of the following medicines in dispensary based on their
Pharmacological action/class.
Risperidone, Carbamazepine, Diazepam, Acetaminophen, Indomethacin, Ibuprofen, Amitriptyline, Diclofenac,
Bisacodyl, Metoclopramide, Castor oil, Ampicillin, Metronidazole, Tinidazole, Cephalexin,
Doxycycline, Ceftriaxone, Erythromycin, Clarithromycin, Azithromycin, Gentamicin,
Ciprofloxacin, Norfloxacin, Artisunate, Chloroquine, Quinine, Mebendazole, Griseoflovin,
Fluconazole, Acyclovir, Zidovudine, Efavirenz, Ritonavir, Albendazole, Isoniazid.
1. ANALGECICS (NSAIDS) DRUGS.
2. CNS DRUGS
3. ANTI PROTOZOA

4. ANTIBACTERIAL DRUGS

5. ANTI VIRAL DRUGS

6. GIT DRUGS
10 collected and prepared by:- Bekuwet Solomon Bekele (Ye Yeshared Lij