D E PA R T M E N T O F S C I E N C E A N D T E C H N O L O G Y 1

P H I L I P P I N E C O U N C I L F O R H E A LT H R E S E A R C H A N D D E V E L O P M E N T
DOST-PCHRD

PCHRD
ANNUAL REPORT

20
Forty years of transforming lives through
health research and development

22
 D E PA R T M E N T O F S C I E N C E A N D T E C H N O L O G Y
P H I L I P P I N E C O U N C I L F O R H E A LT H R E S E A R C H A N D D E V E L O P M E N T
DOST-PCHRD

PCHRD
ANNUAL REPORT

20
Forty years of transforming lives through
health research and development

22
4 PCHRD ANNUAL REPORT 2022 5

The lead coordinating body

for health research in the The Philippine Council for Health Research and Development
(PCHRD) is one of the three sectoral councils of the Department
of Science and Technology (DOST). It is a forward-looking,

Philippines partnership-based national body responsible for coordinating

and monitoring research activities in the country.

DOST-PCHRD
DEPARTMENT OF SCIENCE AND TECHNOLOGY

Philippine Council for

Health Research and Development VISION CORE VALUES
The PCHRD as the recognized lead provider of research-
based solutions and innovations to address health
system needs by 2028.

MISSION
As the national coordinating body for health research,
P assion for excellence and
innovation in public service

we provide central direction, leadership and coordination

C
of health research activities. To achieve this, we are
ulture of teamwork and
committed to do the following: collaboration
• Formulate agenda, plans, policies, and strategies for
health research

H
• Mobilize resources to support health research
• Develop and strengthen capacity for health research
igh regard for work ethics
• Support the development of affordable, accessible,
and integrity
and quality S&T-based solutions and innovations

R
• Ensure the dissemination and utilization of health
research outputs esponsive personal
• Monitor and evaluate health research activities effectiveness
• Establish linkages and partnerships with local and
international organizations
• Promote good governance among health research
organizations through efficient, effective, transparent, D ynamic involvement in
quality management system
and ethical health research management system.
6 7

MESSAGE FROM THE

DOST SECRETARY
“Building on your legacy for the past 40 years,
I am confident that PCHRD is always one with
SEC. RENATO U. SOLIDUM the DOST in ensuring that the health research
Secretary
Department of Science and Technology community will contribute in the attainment of a
resilient, unified, and sustainable Philippines.”

For the Philippine Council for Health Research and priority health research areas – Addressing and Responding HeaRTNovation Program demonstrated the Council’s Council will never lose sight of its purpose and values.
Development (PCHRD), the year 2022 is a banner year in to COVID-19 through Health. Research (ARCHER), Tuklas commitment in innovating programs that will assist local
terms of making the public aware about DOST’s initiatives in Lunas, Biomedical Devices, Functional Foods, Diagnostics, researchers in the different stages of technology transfer — Building on the Council’s legacy for the past 40 years, I
combating the challenges of the COVID-19 pandemic in the Mental Health, Functional Foods, Disaster Risk Reduction conceptualization to commercialization. The well-received am confident that DOST-PCHRD is always one with the
Philippines. During the global outbreak, the general public and Climate Change Adaptation for Health, Nutrition and conduct of scientific and press conferences, contests, and DOST in ensuring that the health research community
has seen the importance of research and development Food Safety, and Digital Frontiers Technology for Health. exhibitions for your stakeholders is also admirable. Likewise, will contribute in the attainment of a resilient, unified, and
(R&D) and its applications in the filed of health-care, and the digital campaign, “Making your Life Better,” which sustainable Philippines.
this is another milestone for DOST-PCHD as we celebrate As one of the implementing arms of the DOST’s Balik made million engagements in the social media platform
its 40th founding anniversary. Scientist Program and S and T Fellowship Program, DOST- is something we can explore too as we work towards the Salute to the men and women of PCHRD!
PCHRD has shown persistence in tapping into the ingenuity realization of our new battle cry #OneDOST4U.
I am exceptionally proud of the significant progress we, and expertise of Filipino researchers. This strengthens the Maraming Salamat po.
collectively, have achieved this year in the areas of research research and development capabilities of the academe, In the coming year, we will witness the beginning of a
management, capacity building, technology transfer, and public and private sectors, and industry. chapter as we shift the wheel, stirring for the goals of the
research utilization. DOST-PCHRD remains consistently new administration. Seeing how DOST-PCHRD lived by the
strong in monitoring funded projects and in managing more DOST-PCHRD also continued to meaningfully advance mission of providing leadership and direction to the county’s
than 700 million pesos of the Department’s funds to support efforts in research utilization. The launching of the health research initiatives gives me confidence that the
8 9

EXECUTIVE DIRECTOR’S
REPORT

DR. JAIME C. MONTOYA

Executive Director,
Philippine Council for Health Research and Development
To our partners in health and to every Lead Coordinator,
Philippine National Health Research System
Filipino to whom all our efforts are for:

Our partners in health and every Filipino to whom all our Institute of the Philippines (VIP), and the continuation of of our own pool of researchers, we carried out capacity research utilization, we provided support to 12 research
efforts are for: long-running projects such as the Prospective Urban and building activities that cover a wide spectrum of health dissemination projects, provided inputs to 22 proposed
Rural Epidemiological (PURE) study. With the support of our research topics and implemented several scholarship legislations, and provided support to five projects from
It is my pleasure to present to you the 2022 Annual Report 29 Tuklas Lunas partners, we also continued our thrust for programs. This year alone, we monitored a total of 181 Filipino startup companies. This year, we also secured
of the Department of Science and Technology - Philippine local drug discovery and development, exploring promising scholars and welcomed 16 new scholars. We are also proud funding for our HeaRTNovation Hubs Program, which
Council for Health Research and Development (DOST- herbal and drug candidates for priority diseases, while to share that we have six scholars who already graduated will enable us to develop a framework that will guide the
PCHRD). simultaneously building our infrastructure capabilities in this year. from our MD-PhD and MS in Molecular Medicine establishment of innovation hubs in our partner hospitals
the field. This year, we saw the completion of the remaining Programs. and health institutions. We are also proud to share that we
This year has been very special to the Council, as we marked projects for the establishment of the Philippine Biorepository have already launched our HeaRTNovation portfolio, which
our 40th founding anniversary. Through a series of activities Network (PBN), which we foresee will support further To ensure that health research initiatives will adhere to the showcases 41 PCHRD-supported technologies that are
that ran throughout the year, we celebrated four decades research on medicinal plants and their conservation. In highest ethical standards, we worked with the Philippine either ready for adoption, pre-commercialization, or are fully
worth of health research initiatives dedicated to making lives the field of genomics, we stayed true to our commitment Health Research Ethics Board (PHREB) for the accreditation commercialized.
better for the Filipino people. of studying the Filipino genome for the development of of 36 research ethics committees (RECs) and assisted in the
improved and targeted strategies or technologies in disease conduct of 65 capacity building activities on ethical research. To increase appreciation for health research, we continue
Parallel to this commitment, we continued to expand our diagnosis, management, treatment, and prevention. In 2022, This year, we also launched the 2022 National Ethical to intensify our communication strategies that cater to our
support for health R&D – utilizing more than 478 million we saw the commencement of several projects for OMIC Guidelines for Research Involving Human Participants. diverse audiences and stakeholders. In order to provide
pesos for research and development projects, 125 million technologies, such as the study on rare Filipino diseases like a platform for dialogue with the media, we conducted 11
pesos for capacity building activities, and 54 million pesos X-linked Dystonia Parkinsonism or XDP, and the launch of By forging strategic alliances abroad, we are also able to sessions of our Talakayang HeaRTBeat. We also reinforced
for S&T services. We were also able to generate and allocate biosurveillance activities of the Philippine Genome Center expand our support for researchers. Together with Italy, our efforts across all platforms, especially on Facebook
funds for health research with the support of the DOST and (PGC) in Visayas and Mindanao. Similar themes of sustained we are currently implementing capacity building programs where we now have over 75,000 followers. This year, we
our partner institutions both here and abroad. growth and development can also be seen across all our at the University of Trieste, University of Pisa, and the also saw the success of our “Making Your Life Better” digital
supported research programs, which you can read more as Fondazione Italiana Fegato (FIF). Our partnership with FIF campaign with more than a million engagements, which
Building on our previous achievements, we continue to note you browse through this publication. also enables collaborative work on liver studies between highlighted the Council’s contribution to health research and
significant growth from our supported projects across our the two countries and will eventually pave the way for the its impact on improving the lives of the Filipino people.
priority research areas. Expected to emerge as one of our Likewise, we continue to invest in building the country’s establishment of the Philippine Liver Network. We also
biggest programs in the coming years, our Re-emerging and capacity against COVID-19 and in assisting our communities have two ongoing projects with Singapore: one with the What I mentioned here are only examples of our work and
Emerging Diseases or RED Program received the biggest transition to the new normal. This year, we allocated more Singapore Diagnostics Development Hub (DxD) Hub who accomplishments for 2022. With this report, I hope not to only
chunk of combined investment from the DOST and the than 85 million pesos for projects related to COVID-19 is our co-chair for the ASEAN Diagnostics Initiative (DxI), share our progress, but to also reinforce our commitment: to
PCHRD in 2022. The allocation supported the advancement through our Addressing and Responding to COVID-19 and the other with the Agency for Science, Technology, and make lives better for the Filipino people through health R&D.
of several projects that cover a diverse range of focal areas in through Health Research or ARCHER Program. This Research (A*STAR) for the establishment of innovation hubs
the field, including the commencement of the Inter-Regional allocation supported a total of 17 projects, 15 of which are in the Philippines. On behalf of the Council, I thank everyone who has been
Network through One Health Approach to Combat AMR already completed. with us for the past 40 years.
program, the approval and implementation of several studies All our initiatives, of course, are meant to be translated
under the soon-to-be established Virology and Vaccine Recognizing the critical importance of nurturing the growth into outputs that will benefit our communities. In terms of
40
10 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 11

years of
PCHRD was created on March 17, 1982 through
Executive order No. 784. In 1987, Executive Order
No. 128 reaffirmed its existence and relevance. This making life
better for the
directive reorganized the National Science and
Technology Authority into what is now the
Department of Science and Technology.

Filipinos
 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 13
12

HeaRT for the Filipino: Pananaliksik Pangkalusugan para sa Pilipino

The kick-off event

To commence the beginning of the year-long anniversary celebration, a kick-off event entitled, “HeaRt for the Filipino:
Pananaliksik Pangkalusugan para sa Pilipino,” was held on 17 January 2022 via Zoom video conference and live
simulcast in its DOST-PCHRD Facebook page.

In the event, the Council launched the Visualized Health Research 2.0, a visual abstract contest which aims to translate
results of PCHRD projects which are published in scholarly journals into visual abstracts that will be posted in Facebook
and Twitter. Intellectual Property and Technology Management (IPTM) Programs and Services were also launched in
the event.

40-Day Video Countdown

A year-long celebration of
PCHRD’s 40 years
In the past 40 years, the DOST-PCHRD, together with its partners, worked to provide
research-based solutions for health. With the theme, “PCHRD @ 40 and Beyond:
Transforming Lives through Health Research and Development,” a series of activities
for the whole year was prepared, which highlights every aspect of its initiatives in
health – from supporting R&D, strengthening the capacity of its pool of experts, to
bringing research outputs to utilization.

On 7 February 2022, the first of the 40 videos was released in the DOST-PCHRD Facebook page to mark the 40-day
countdown to the anniversary main event. Each video contains significant accomplishments of the Council each
year since its inception in 1982 so stakeholders can look back on its important contributions as it reaches its 40th
anniversary.
 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 15
14

Drawing on Collective Strengths for Pandemic Preparedness: Launch of SARS- CoV-2

Genomic Biosurveillance Services at UP PGC Visayas and Mindanao

On 11 March 2022, in a virtual event co-hosted by the

DOST-PCHRD, the University of the Philippines (UP),
through its Philippine Genome Centers (PGCs) in
UP Visayas and in UP Mindanao, announced that it is
capable of sequencing the genome of SARS-CoV-2 from
community samples in both island groups.

The fully-equipped satellite facilities, made possible

through the joint efforts of UP, the Department of Science
and Technology (DOST), the Department of Health (DOH),
and the Department of Budget and Management (DBM),
began genome sequencing services of nasopharyngeal
or oropharyngeal swab samples from DOH-licensed
COVID-19 testing laboratories in cooperation with the
DOH - Epidemiology Bureau (DOH-EB), to detect SARS-
CoV-2 variants circulating in the Visayas and Mindanao
regions.

In the first quarter of the year, UP-PGC Visayas worked The Main Celebration human participants in research will be protected, even
with the Western Visayas Medical Center for the those involved in non-health research projects.
collection and viral RNA extraction of samples prior to A three-day virtual celebration on 16-18 March 2022 via
sequencing. From January-December 2022, the UP-PGC Zoom and Facebook live streaming was held to celebrate Another highlight was the awarding and recognition of the
Visayas successfully sequenced a total of 5,128 samples the 40th Anniversary of DOST-PCHRD. The event PHREB-accredited Research Ethics Committees. A total
and submitted the results to the DOH-EB for analysis and provided a platform for participants from the of 13 Research Ethics Committees (REC) were awarded
endorsement to the Regional Epidemiology Surveillance with accreditation, with 8 RECs at Level 1, 2 RECs at Level
Units (RESUs). The RESUs report supplements the academe, policymakers, private sector, and civil society 2, and 3 RECs at Level 3.
respective local government units (LGUs) strategy to representatives to converse on advancing the landscape
mitigate the transmission of circulating variants in the of the country’s health research in the next decade. In the afternoon, two parallel sessions were held. First,
concerned areas. hosted by the UPSCALE Innovation Hub, the University
Day 1: Pre-conference Innovation Fellows (UIF) for Health Demo Day showcased
Similarly, the UP-PGC Mindanao team worked with the The first day of the celebration featured the launching of the top seven (7) health-based technologies of the UIF for
Southern Philippines Medical Center (SPMC) for the two publications which were products of partnerships - Health Project that is being funded by the DOST-PCHRD.
sequencing of samples from Mindanao. From January- the Tuklas Lunas Book of Accomplishments and the 2022 The demo day became a venue for technology owners
December 2022,the UP-PGC sequences a total of 1,865 National Ethical Guidelines for Research Involving Human to network and engage with industry partners, potential
samples. Participants (NEGRIHP). customers, and collaborators. The UIF for Health project
is implemented by the UPSCALE Innovation Hub of UP
The national effort for genomic biosurveillance of SARS- The Tuklas Lunas Book of Accomplishments highlights a Diliman in cooperation with the UP System, UP Manila,
CoV-2 is a collaboration among different agencies. decade’s worth of research and innovation in the field of UP Diliman, and UP Visayas Technology Transfer and
Laboratories and other institutions, through a coordinated drug discovery and development. Through the years, the Business Development Offices.
chain of roles and responsibilities, aim to provide local and program has partnered with 30 institutions across Luzon,
national authorities with data and scientific evidence on Visayas, and Mindanao on more than 60 research projects, The second session, an education forum entitled: “How to
the circulating SARS-CoV-2 variants in the archipelago. spanning a diverse range of possible herbal formulations Prepare a Peer Review Report,’’ was held in partnership
and drug leads for priority diseases. The book also aims to with the Philippine Association of Medical Journal Editors
promote continuity and serve as a guide for researchers (PAMJE). Around 500 participants in this session learned
who will further pursue projects in the field. a suggested structure for manuscript review; gained an
overview of comments to the editor and comments to
On the other hand, the 2022 NEGRIHP is an updated authors; and discussed examples on how to prepare a
version of the 2017 National Ethical Guidelines for Health peer review report. After the educational forum, the PAMJE
and Health-Related Research (NEGHHR). The updated General Assembly was conducted and attended by its 51
version is made to be more inclusive, to ensure that all members.
16 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 17

Day 2: Opening Ceremonies National Comprehensive Newborn Screening Program,

In his message during the opening ceremonies, DOST which is now supported by Republic Act 9288 or the
Secretary Fortunato de la Peña recounted what it was Newborn Screening Act of 2004 Relative to this, she
like for the health research community 40 years ago. He addressed funding agencies to emphasize how important
said, “Before PCHRD was founded 40 years ago, there it is to believe in ideas, whether big or small. “Big things
was no organized body that would provide leadership to come from small ideas. And no matter how small an idea
all health research initiatives in the Philippines. What is is, they should be given a chance to be proven in the
normal today – a coordinated framework, and an enabling context of science and research,” said Dr. Padilla.
environment for health innovators – was just a vision in
1982 that required determination and vigor to make every Compared to when it started, the program was able to The journey of health R&D she said. Aside from this, she added that the deficiency of
Filipino’s life better.” significantly expand its coverage, which now screens for Starting with the growth of health research in the country, specialized equipment is also a difficulty the regions have
29 conditions and is implemented by more than 7000 the panel discussed the changes in the sector over the to overcome.
Meanwhile, in his welcome message, DOST-PCHRD facilities in the country as cited in the Department of decades.
Executive Director Jaime C. Montoya, promised that Health website. Dr. Padilla proudly reported that through On the other hand, Dr. Saniel commended the growth of
the Council will take bolder strides moving forward to the years, “the program has saved thousands of newborns Dr. Maramba shared her experiences as a founding the health research landscape as a whole. “The breadth
support our health researchers. “In the past 40 years, from mental retardation and death.” member of the National Integrated Research Program and depth of the research that has been done in the
the DOST-PCHRD, together with its partners, worked to on Medicinal Plants (NIRPROMP). Developed in six country is truly amazing,” said Dr. Saniel, emphasizing
provide research-based solutions for health. Recognizing In completing research projects, she reminded months, she shared how the institution came to be. “We the importance given by the current health research
the dynamic field of healthcare, we continuously expand researchers to keep the greater good in mind and to had only one goal and that was to serve the needs of community in the implementation of the National Unified
and assess the scope of our services to respond to the bring their research output to the people. She also the Filipinos, especially in the rural areas.” Focusing on Health Research Agenda (NUHRA). According to her, this
changing needs of our communities. In the new normal, emphasized how the future for health research is a improving the access of the Filipino to treatments through has guided the direction of health research efforts, helping
PCHRD’s new life will begin at 40.” shared responsibility: “With government funding and herbal medicine, the NIRPROMP has patented at least 10 Filipino researchers to be recognized globally through
the academe for a nurturing environment, and the medicinal plants to date. their works.
The Keynote Message researchers for the continuous supply of new solutions
Ideas should be given a chance to be proven in the context for the old and new issues of the country.” Also specializing in drug discovery research is Dr. Dalisay. Despite notable progress, Philippine health research
of science and research – UP Manila Chancellor She pointed out the lack of academic programs and continues to adapt to the most pressing national health
Then, Now, and Futures of Health Research in a facilities for her desired research area in the 90s which concerns. The panel shared some advice to current and
University of the Philippines Manila (UPM) Chancellor changing world: A talk show led her to pursue graduate studies in Australia. However, aspiring health researchers on how to ensure that health
Carmencita Padilla highlighted the importance of One of the highlights of the opening ceremonies was through the DOST’s Balik Scientist Program (BSP), she research continues to benefit Filipino communities in the
believing in research ideas by citing her work on newborn the talk show entitled, “Then, Now, and Futures of Health returned to the Philippines to share her expertise on marine future.
screening in 1996, in her keynote message. Research in a Changing World.” Health researchers microorganisms. She shared updates on her engagement
Dr. Nelia Maramba of the University of the Philippines as a DOST Balik Scientist, “For the last four years, we Health research moving forward
She narrated how she and her mentor Dr. Carmelita College of Medicine (UPM CM), Dr. Mediadora Saniel of were able to create our own collection of these diverse Citing her experiences with the NIRPROMP, Dr. Maramba
Domingo initiated the newborn screening project in 24 The Medical City, Dr. Doralyn Dalisay of the University microorganisms from all over the Philippines.” Currently, emphasized the role of S&T in providing answers for those
hospitals in 1996. The newborn screening test entails of San Agustin (USA), and Dr. Joycelyn Jumawan of the Dr. Dalisay’s team has around 3,000 highly diverse marine who actively seek information. She hopes that researchers
getting a few drops of blood from the heel of a newborn Caraga State University (CSU) shared their journey in sediments stored in a biobank in the USA which may be will be more receptive to questions and feedback from
to run tests to diagnose certain conditions that can conducting research over the years and their vision of the used for drug discovery. end-users. “We should be able to give what they [end-
be treated immediately to save the baby from mental health research landscape in the coming decade. Dr. Eva users] are asking for as far as information is concerned,”
retardation and death. Needing to cover 18 private and Maria Cutiongco-De La Paz, Executive Director, National Representing regional researchers, Dr. Jumawan cited she said. According to her, this helped in encouraging the
six government hospitals for an adequate sample size, Dr. Institutes of Health, UPM, served as the talk show host. the lack of researchers as one of the major barriers to use of herbal medicine, in the context of her work with
Padilla shared how they worked to secure funding for the the growth of health research in the regions. “I believe NIRPROMP.
project from the DOST-PCHRD and UPM. She shared it is about time to put a premium on programs and
how the support from both institutions paved the way scholarships on health research, especially for takers from For Balik Scientist Dr. Dalisay, Philippine health research
for the research project which became the basis for the the regions to increase the number of health researchers,” should be prepared for opportunities amid the widespread
18 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 19

digitalization in healthcare. She envisions interoperable With the threat of re-emerging and emerging diseases to
data, sophisticated tests, and early diagnostics to be public health, the Re-emerging and Emerging Diseases
available among the centers of healthcare in the future. (RED) program is an expansion of the DOST-PCHRD’s
Mentioning the surge of digitalization in healthcare Dengue and Other Arboviruses program. It supports
due to the pandemic, Dr. Dalisay believes that these R&D that generates local and novel technology platforms,
advancements “will harmoniously bring together in therapeutics, preventive measures, surveillance, and
order to provide a sustainable well-being to Filipino control and management protocols for various diseases.
communities.” She added that there could be increased The program is intended to equip the country’s health
capabilities in diagnosis, intervention to delay or eliminate systems with research-based solutions and innovations
the onset of diseases, and cure delivery. for better disease management and prevention.

On the other hand, Dr. Jumawan expressed her hope for On the other hand, the Digital and Frontier Technologies
increased support for emerging and regional researchers. for Health program builds from the Council’s Information
She said that funding and training on the conduct of and Communication Technology (ICT) for Health
research up to its utilization will encourage more regional program. To respond to eHealth needs emphasized by
researchers to undertake R&D and empower them to the implementation of universal health care (UHC), the
apply for grants. She also highlighted the importance updated research program now focuses on R&D utilizing
of capacitating the regions in health research ethics. artificial intelligence and other elements of the 4th
“Academic institutions in the CARAGA region have yet to industrial revolution, connectivity platforms and new fields
establish their own PHREB-accredited academe-based of digitalization.
ethics review committee,” Dr. Jumawan said, sharing the
current status of health research ethics in her region. “We Another program, the Nutrition and Food Safety Program
would really welcome more training in order to increase aims to address various malnutrition and food safety issues
the number of the members of the committee so we can using science and technology. This research priority area
really assist and accommodate reviewing proposals for hopes to cover studies on the nutrition of all age groups
professionals as well as students,” she added. (pediatric, adolescent, adult, and geriatric), malnutrition
and its relation to infectious diseases, use of innovative
Lastly, Dr. Saniel called on the PCHRD to initiate efforts technologies such as omics for individual diets, fad diets,
toward the prioritization of research on universal nutrition for the disabled as well as for athletes or people
healthcare. “For PCHRD, to really identify what are the active in sports, safety of foods sold in the local markets,
priority areas for implementation research for universal and tools that can be used to identify and prevent diseases
healthcare. I think that is urgent,” she said. Dr. Saniel also related to food safety.
cited antimicrobial resistance and impact evaluation In the second part of the session, six S&T Fellows who
as areas of health research that should be given more participated in various R&D management-related activities
attention moving forward. such as program conceptualization and assessment,
strategy and policy development, and monitoring and
Day 3: Technical Sessions evaluation were introduced.
Three technical sessions were conducted on the last day
of the anniversary main event. The S&T Fellows deployed in DOST-PCHRD are tasked
to focus on specific health research priority areas, are as
Session 1: Introduction of new R and D programs and follows:
PCHRD S and T Fellows

One of the flagship services offered by the DOST-PCHRD • Dr. Aimee Yvonne Criselle Aman for OMIC
is its research grant services that provides funding and Technologies for Health
assistance to Filipino researchers in the conduct of health • Dr. Ma. Neda Catalma for Functional Foods, Nutrition,
research. To ensure that the Council invests in projects that and Food Safety
solve pressing, real-world problems; it outlines research • Dr. Adam Christian Espiritu for Diagnostics
priority areas with specific topics for each round of call for • Dr. Phoebe Nicole Perez for Biomedical Devices and
proposals. In the first part of this session, three new R&D Engineering for Health
priorities of the Council were introduced namely: • Dr. Albert Remus Rosana for Tuklas Lunas
• Re-emerging and Emerging Diseases • Dr. Ranhel De Roxas-Bernardino for Digital and
• Digital and Frontier Technologies for Health, and Frontier Technologies for Health
• Nutrition and Food Safety
20 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 21

Session 2: Today and Beyond: Strengthening the country’s Technology, Research, and Innovation for Development
capacity in research Chief of Party Dr. Richard Abendan, World Intellectual
Property Office- Asia Pacific Bureau Director Atty. Michael
The second session entitled, “Today and Beyond: Andrew Ong, Philippine Association of Medical Journal
Strengthening Country’s Capacity in Research” aims Editors President Dr. Cecilia Maramba-Lazarte, Research
to gather some of the Council’s staunch partners Institute for Tropical Medicine - Immunology Department
representing Luzon, Visayas, and Mindanao to converse Head Dr. Mario Jiz and a Science Communicator based in
about their region’s achievements, current initiatives, Singapore Ms. Kamila Isabelle Navarro.
and plans to bolster the country’s capacity, including the
infrastructure, systemic relationships, scholarships, and The questions revolved around the experiences of the
ethics in health research. resource persons in using different pathways in research
utilization namely, policy making, technology transfer,
In this dialogue, Dr. Lyre Anni Murao, Program Director journal publication, and information dissemination for the
of the Philippine Genome Center Mindanao, Dr. Julius public.
Capili, Director of Cagayan Valley Health Research
and Development Consortium, and Dr. Edgardo Tulin, Director Mamaril gave her perspective as someone who
President and University Professor at the Visayas State works in the DOH. According to her, research is important
University, shared about the past, present, and future of because it is the backbone of objective and evidence-
health research capacity in the Philippines. informed policy planning and program development in
Dr. Capili expressed how the research undertaking in their department. She gave emphasis on the importance
Luzon has improved in the past decades, from being of health policy in the daily decision-making of the DOH
regarded as “just satisfactory” to now having a clear-cut which in turn creates impact in the lives of the Filipinos.
research direction through the establishment of a health
research agenda, and appreciating the dynamism of the For Dr. Abendan, bigger partnerships with the government
consortium. and the academe create innovative work in health research
that would leverage more impact. As an example, he
For Visayas, Dr. Tulin highlights, “Health research was not talked about the partnership of the STRIDE program with
as aggressive but that was a good start for the people the DOST and other government agencies in providing
in the region.” Dr. Tulin recalled that many research capacity building not only for Filipino researchers but also
initiatives in the region from the past were only focused on to science communicators who have an important role in
antibacterial and anti-microbial properties coming from ensuring research results reach the target users..
natural products and indigenous plants, as well as animal
research and agriculture-related R&D. He emphasized
that the establishment of the Consortium in 1982 is a “very Attorney Ong, on the other hand, emphasized the
good strategy” for the region as it paved the way for many importance of being knowledgeable about the Intellectual
researchers in the region to be funded by the consortium. Property and Technology Transfer Laws. According to him,
As described by Dr. Murao, “In Mindanao, Health research researchers should know the terms of transacting and
is growing, and it is growing in the right direction.” She licensing in negotiating research outputs, and ensuring
added that there has been an increased number of that it is protected. In this way, researchers would reap the
proposal submissions, an increased Regional Research full commercial benefits of their discoveries or innovation.
Fund, and the existence of big-ticket programs in different
institutions in the region. It is through publication that research results are
disseminated to other researchers that’s why Dr. Lazarte
The session moderator was Dr. Unity Cortez, Chief of encouraged researchers to publish their research
Medical Professional Services of the Ilocos Training and results in respectable journals to contribute to the body been and how these investments help in capacity building and in enhancing research facilities. He emphasized that
Regional Medical Center. of knowledge, thus, make an impact. Dr. Lazarte also communicating science is vital in gaining the public’s trust that will lead to better interventions, health programs, and
reminded researchers, especially the beginners, the improve the lives of the Filipino community.
Session 3: Research Utilization: A road to impact importance of having good mentors who can guide and
direct them in choosing topics that will achieve the utmost Ms. Navarro, on the other hand, specified time, training, and local science culture as some of the challenges in
The final session was a one-on-one interview with six impact for the community. communicating science in the country. She also had given health researchers some tips in effectively communicating
experts who have been using results of research to by identifying the audience and keeping the messaging short and simple. “Science communication is not a one-time
make an impact or create a change in society or in Dr. Jiz and Ms. Navarro’s interview revolved on the thing, it’s an ongoing skill that has to be learned and improved continuously,” she added.
their community. They were as follows: Department of importance of translating science information for the public.
Health (DOH) - Health Policy Development and Planning According to Dr. Jiz, researchers, especially those who The session moderator was Dr. Jason Ligot, Director for Development Communication at Organic Intelligence.
Bureau Officer-in-charge Dir. Frances Rose Elgo-Mamaril, gain support from the government, have the responsibility
US Agency for International Development-Science, to tell the people how good research investments have
 22 PCHRD ANNUAL REPORT 2022 40TH ANNIVERSARY 23

Pagpupugay at Pasasalamat: 40 Taon ng

Pananaliksik Pangkalusugan Para sa Pilipino
A Recognition Day

To recognize the notable contributions of Filipino health researchers and research institutions in realizing the mission
of the DOST-PCHRD, a hybrid event entitled, “Pagpupugay at Pasasalamat: 40 Taon ng Pananaliksik Pangkalusugan
Para sa Pilipino,” was held on 10 June 2022, at the Philippine International Convention Center (PICC), Pasay City and
live streamed in DOST-PCHRD Facebook page.

Certificates of appreciation were given to Technical Reviewers, Technical Working Group, Technical Advisory Group,
Partner Institutions, Regional Health Research and Development Consortia, Philippine Biomedical Device Innovation
Consortium, PNHRS Week Regional Host, media members, DOST-PCHRD Governing Council members, past
PCHRD directors, and DOST officials.

Present and past PCHRD staff were also in attendance. DOST Secretary Fortunato de la Pena, who was also recognized
for his service and support to PCHRD, gave a heartfelt message:

“Ako ay nagagalak na masaksihan ang pagbibigay-pugay at pagkilala sa lahat ng Pilipinong siyentista, mananaliksik,
at mga katuwang ng PCHRD sa pananaliksik. Kami ay lubos na nagpapasalamat sa inyong serbisyo para sa bayan
gamit ang siyensya upang makapagbigay solusyon sa mga isyu at problemang pangkalusugan na kinakaharap ng
bawat Pilipino.”

Isay Alvarez, and her husband Robert Seña, the Bayanihan, National Dance Company of the Philippines, and some
veteran poets such as Bong Cabrera, Liway Perez, Pere Santiago, and Vince Conrad, performed in the said event.

PCHRD Services Clinic. To conclude the year-long

anniversary celebration, a PCHRD Services Clinic
was held last 14 December 2022 at the Philippine
International Convention Center as a side activity of the
mental health public forum. Participants of the forum
was able to get the latest information about the services
and programs offered by the DOST-PCHRD from
research proposal making up to research utilization.
24 PCHRD ANNUAL REPORT 2022 25

T ogether with the Central Luzon Health Research and

Development Consortium (CLHRDC), the DOST-PCHRD
organized the 15th Philippine National Health Research System
(PNHRS) Week at the Clark Marriott Hotel, Pampanga on 8-12
August 2022. The event was conducted in a hybrid format with
limited face-to-face and virtual conference through Zoom and
Facebook live. With the theme, “Health Research: Responding
to Challenges towards National Recovery and Resiliency,” the
celebration highlighted the experiences, best practices, and
discoveries in coping with the pandemic and other natural
calamities and disasters that can be utilized and translated into
the 6Ps (Publication, Patent, Product, People Services, Places and
Partnerships, and Policies) and 2Is (Social and Economic Impact)
as means for the country’s recovery, resiliency, and nation-building.

The physical event was attended by 250 delegates from all 17

regions of the country including BARMM, and around 6,900
virtual participants joined the main conference through Zoom
and Facebook live.

A side from this, the celebration had 14 pre-

conference sessions and three plenary
sessions in the main conference attended by
Institute of the Philippines (VIP) and the Center
for Disease Control (CDC). He also expressed his
gratitude to the health research community for its
an average of 3,000 participants in the virtual contributions to the country’s pandemic response
platform. and encouraged them to continue the collective
goal of improving every Filipino’s life.
For the first time in the history of
PNHRS, the President of the Republic The heads of the PNHRS implementing agencies,
Undersecretary Maria Rosario Vergeire of
of the Philippines attended the PNHRS
the Department of Health (DOH), Chancellor
Week celebration. President Ferdinand
Carmencita Padilla of the University of the
Marcos, Jr. graced the event as the Philippines Manila, Chairman J. Prospero De
keynote speaker during the opening Vera III of the Commission on Higher Education
ceremonies of the main conference. (CHED), and DOST Secretary Renato Solidum,
represented by the DOST Region III Director
He expressed his administration’s full support to the Julius Caesar Sicat, also graced the celebration
health research community, and vowed to push and addressed the health research community
for the establishment of the Virology and Vaccine through each of their messages.
26 PCHRD ANNUAL REPORT 2022 15TH PNHRS WEEK 27

Visual Abstract Poster Exhibit and

Competition
(Student and Professional Category) Winners of the Professional Category

A successfully completed health research study, especially 1st Place Chuckcris Tenebro University of San Agustin

with substantial results, must be communicated to benefit

2nd Place Dr. Penuel David Centro Escolar University - Malolos
key stakeholders. To foster researchers’ presentation,and Campus
communication skills, a visual abstract poster exhibit and 3rd Place Dr. Andy Catulin Cagayan State University
competition was held as part of the 15th PNHRS Week People’s Choice Mheljor General Bicol University
celebration.
Winners of the Student Category
The Visual Abstract Poster Competition – Student 1st Place Anne Gwyneth University of the Philippines Visayas
Category was held on 9 August 2022 via Zoom Video Traya
Conference while the Professional Category was held on 2nd Place Norianne Bolibol Mariano Marcos Memorial State
University
10 August 2022 at the exhibit area in Clark Marriot Hotel,
3rd Place Jaira Jade Milan- Cagayan State University
Pampanga. The competition requires researchers to dres
translate the results of the abstract of their study in visual People’s Choice Jesille Mae Legarta University of the Immaculate Con-
format for easier dissemination to stakeholders. ception

The plenary sessions at the main conference addressed • Visual Abstract Poster Competition,
two (2) subthemes. First, “Pandemic to Endemic: • 3-Minute Pitch to Policymakers Competition,
Shaping Disaster Resilient Communities from COVID-19 • National Medical Writing Workshop,
Experiences” which highlighted how the experiences from • PNHRS Research Agenda Committee Meeting, and
COVID-19 and other disasters shaped disaster resilience • RHRDC Secretariat Meeting.
across different sectors, especially the health research
community. Second, “Build Back Better for National The awarding ceremonies for the Philippine Health
Recovery and Resiliency,” prompted that as the pandemic Research Ethics Board (PHREB) Research Ethics
gradually abated in our local context, the direction of Committees (REC) Accreditation, Oral Research Paper
national recovery should not be a return to “business as Competition for the Grantees of the DOST-PCHRD
usual” but to shift to a more resilient Philippines. Undergraduate Thesis Grant in Natural Products, Research
The pre-conference events featured the following sessions, Poster Competition (Student and Professional Category),
competitions, workshops and committee meetings: 2021 Best Mentor Cluster and National Winners, and 2022
• Ethics Forum and Training, Gelia Castillo Award for Research on Social Innovations in
• Intellectual Property and Technology Management Health was also conducted during the closing ceremonies.
(IPTM) Call Conference, It was announced that the next PNHRS host will be the
• Enhancing PNHRS M&E System, Eastern Visayas Health Research and Development
• Strengthening PNHRS Resource Mobilization, Consortium (EVHRDC).
• Oral Research Paper Presentation,
28 PCHRD ANNUAL REPORT 2022 15TH PNHRS WEEK 29

PNHRS Law IRR Registration

and Publication
In 2019, the PNHRS implementing agencies came up with a revision of the
Implementing Rules and Regulations (IRR) of the PNHRS Act of 2013 or
RA 10532.

The Council, being the PNHRS Secretariat, finally received

the hand-signed copies of the revised IRR on 19 January
2022, and immediately facilitated the rectification of the
revised IRR’s Joint Administrative Order Number in order
to avoid any technical, procedural and/or legal implication.

The PNHRS Secretariat then facilitated its registration to the University of

the Philippines-Office of the National Administrative Register (UP-ONAR)
and publication to the Official Gazette. The revised IRR was published to
the Official Gazette last 19 December 2022, and was filed in the UP Law
Center on 25 April 2022. The revised IRR was made effective on 3 January
2023.
30 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 31

1
PART To ensure that
research results
support the
development of
affordable, accessible,
and quality S&T-
RESEARCH AND
DEVELOPMENT
based solutions
and innovations,
the Council funds
research aligned
with the PCHRD’s
research priority
areas in health
32 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 33

142

Distribution 130

R&D of R&D
Highlights projects in
74
65
2022
To ensure that research results support the development of affordable, accessible,
and quality S&T-based solutions and innovations, the Council funds research 38
34
aligned with the PCHRD’s research priority areas in health DOST-Funded

PCHRD-Funded

COMPLETED NEW ONGOING

Research Expenditures in 2022

1DDE
Ten priority areas in health research

Php Php Php • Tuklas Lunas®

331 767 1.1 • Functional Foods

million million billion • Nutrition and Food Safety
• Mental Health
• Disaster Risk Reduction and Climate
Change Adaptation in Health
• Omic Technologies for Health

1DEPA1DEP 1D1EP
• Biomedical Devices Engineering for Health
• Re-emerging and Emerging Diseases

Budget utilization • Digital and Frontier Technologies for Health

• Addressing and Responding to COVID-19
rate in 2022 through Health Research (ARCHER)
34 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 35

TUKLAS LUNAS ® T he Tuklas Lunas® Program is the drug discovery and adopted a strategic framework that pursues two tracks
development program of the DOST and PCHRD of development: (1) Herbal (Biodiversity/Folkloric) track:
which envisions to “produce world-class medicines development of standardized herbal drugs, (2) Drug
derived from the Philippine biodiversity, leveraging on (Synthesis/Pure Compound) track: the identification
local expertise”. of high-value compounds that can be offered for early
licensing for further development as drugs. In the process,
Building on the experience and successes of the National several outputs may be produced such as functional food,
Integrated Research Program on Medicinal Plants standardized herbal supplements, standardized herbal
(NIRPROMP) which produced lagundi and sambong drugs, and pure drug candidate compounds.
herbal drugs now valued to be a PhP 1 billion industry,
Tuklas Lunas aims to further tap into the potential of The Tuklas Lunas® program supports the following:
Philippine biodiversity as sources of drug candidates, • Building institutional and human capacity for
contribute to addressing local need for more safe, discovery and development of natural products
effective, affordable and accessible locally-developed through R&D grants;
health products; and to the growth of the local natural • Developing bioresources (unique in the regions) into
products and pharmaceutical industry. natural products; and
• Bringing candidate substances/compounds to a
Recognizing that significant resources are needed to bring stage where they are sufficiently de-risked and ripe
one (1) successful drug candidate from early discovery for early licensing (not necessarily for full product
to commercialization, the Tuklas Lunas program has development).

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 61,048,265.66

10NEWLY-APPROVED
19 COMPLETED
7 NEWLY-IMPLEMENTED
54 ONGOING
41 PROPOSALS PROCESSED
DOST
PhP 226,108,186.61
36 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 37

World-class
medicines derived
from the Philippine
biodiversity
38 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 39

Tuklas Lunas from Endemic/Indigenous

2022
infective activities against ESKAPE pathogens
Plants in Bicol with Pharmacological • Created an online repository of information
Activity against Diabetes, Obesity and

Tuklas Lunas
regarding medicinal plants
Hypertension
IA: Bicol University
• Generated five compounds with beta-lactamase
inhibitory activities ®
• Conducted testing to confirm the bioactivity and • Standardized non-toxic alcoholic dosage form with

Accomplishments
safety of extracts from 23 different plant species: anti-diabetes properties
• Four plant extracts confirmed to be non-toxic and • Formulated antimicrobial creams against
have anti-hypertensive properties Staphylococcus aureus, MRSA, and Pseudomonas
• Two plant extracts confirmed to be non-toxic and aeruginosa
have anti-diabetic properties
• Five plant extracts confirmed to be non-toxic and Securing the Health of the Filipino for the
have anti-obesity properties Next Millennium: The National Institute
of Health, National Clinical Trials and
Translation Center (NIH NCTTC)
Discovery and Development of Health IA: UP Manila - National Institutes of Health
Products (DDHP): Disease-Specific Established SOPs for the operational procedure of
Bioactive Hits from Terrestrial Organisms the facility and initiated partnerships with 17 local and
IA: UP Manila, UP Diliman, UP Baguio, Benguet State international organizations
University, UP Mindanao, and Pascual Laboratories
• Produced 247 extracts obtained from priority Nanostructured Herbal Extract of
samples Momordica charantia (Bitter Melon/
• Obtained 252 bioactive and non-toxic semi-pure Ampalaya), Allium sativum (Garlic)
subfractions (against disease indications such as and Curcuma longa L. (Turmeric) as
diabetes, inflammation, hypertension, gout and Antidiabetic Agents
obesity) from the 247 extracts generated IA: DOST-Industrial Technology Development Institute
• Submitted 64 fractions for secondary assays • Developed the preliminary formulation (cocktail)
of three herbal extracts, which were tested for
Potential Anti-Cancer Leads from Plants in antidiabetic activity in rats.
Region XII
IA: University of Southern Mindanao Chemical and Biological Characterization
• Revealed that out of 66 crude extracts from 46 of Pure Bioactive Compounds from Kadios
plant samples, 25 plants showed antiproliferative
(Cajanus cajan) Seeds and its Topical
Formulation Studies
and 30 with anti-migratory activities on liver cancer
IA: University of San Agustin
cell lines (HepG2). All are deemed safe for liver and
• Identified two antibiotic markers in C. cajan seeds
kidney cells except for one sample which should be
against S. aureus strains, including the multi-drug
taken with precaution.
resistant strain (MDRSA)
• Confirmed the anticancer activity of 23 crude plant
• Elucidated the mechanism of action of the main
extracts on human colorectal cancer cell lines
antibacterial compound against MDRSA
(HCT116).
• Formulated different topical antibiotic formulations
• Revealed the top 15 plant samples that will be
incorporating C. cajan seeds antibiotic secondary
subjected for separation, isolation, and purification to
metabolites, in partnership with Maridan Industries
determine the anticancer compounds responsible
for its bioactivity.
Compounds Active Against Cancer Cell
Lines (HCT116, MCF7, A549) from Priority
Documentation, Standardization, and Extracts (Phase 2)
Formulation of Dosage Forms from
IA: UP Diliman
Indigenous Plants and Microorganisms
• Ongoing evaluation of 15 priority plants from
with Bioactivities
which 13 are nontoxic and active. Bioassay-guided
IA: UP Baguio, Benguet Statue University, and Saint Louis
isolation work on the priority active fractions is also
University
ongoing.
• Isolated compounds of the class
epipolythiodioxopiperazine from fungi with anti-
 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 41
40

Development of Anti-inflammatory Herbal Confirmatory and Orthogonal Assays to

Products from Iluko Indigenous Plants Eliminate Artefactual Drug Bioactivities (Phase
IA: Mariano Marcos State University 3): Continuing Needs of Tuklas Lunas Program
• Found that five (5) standardized spray-dried extracts IA: UP Diliman
are bioactive through enzyme-based assays. • Optimized Xanthine oxidase and Uric acid
Results indicated that the extracts are safe for the quantification assays.
liver, heart, and kidney cell lines used for the study. • The following were performed to validate primary
• Ongoing pre-formulation studies to determine assay hits for each disease indication:
the most stable, effective and safe dosage form ○ Diabetes – Glucose Uptake Assay of 36
through the establishment of the kinetic rate samples
profile, compatibility with the other ingredients and ○ Hypertension – Exogenous ACE Inhibition
physico-chemical parameter of the spray-dried Assay of 47 samples
extracts. ○ Inflammation - DCFDA Assay of 21 samples
and COX-2 Activation Assay of 33 samples
Discovery and Development of Health ○ Obesity - Lipid Accumulation Assay via
Products [DDHP]: Formulation, Triglyceride Quantification of 5 samples
Standardization, and Metabolic Profiling of ○ Cancer - RealTime-Glo MT Cell Viability
Disease-Specific Top-Tier Plants for Pre- Assay of 312 samples, Caspase Glo 3/7
Clinical and Clinical Development Apoptosis Assay of 149 samples, Scratch
IA: Pharmalytics, Pascual Laboratories Inc., Herbanext Wound Assay of 235 samples.
Laboratories, Inc, and UP Diliman
Produced and extensively studied 17 plant extracts, and Discovery and Development of Natural Products
accomplished the following: from Mindanao Marine Resources
• Completed spray-dried ethanolic extracts, IA: Mindanao State University – Iligan Institute of
pharmacopeial testings, and acute oral toxicity Technology
testings in four (4) out of five (5) plant samples. Established the following assays for cancer:
• Subjected 8 out of the 12 spray-dried extracts under • Anti-proliferative orthogonal and secondary assays:
preliminary excipient formulations. RealTime-Glo cell viability
• Putatively identified 15 compounds • Pro-apoptotic primary and secondary assays:
• Completed method development/optimization for Caspase-Glo 3/7 Apoptosis assay and Caspase-
four (4) out of five (5) plants. Glo 8 assay
Evaluated the following:
Establishment of the Visayas NMR Laboratory: • Pro-apoptotic and anti-migration activity profiles
Enabling the countryside with the power of of 100 sponge extracts, 16 seahorse and two (2)
magnetic resonance for drug discovery and a pipefish extracts.
forward-looking pandemic response • Pro-apoptotic and anti-migration activity data of 27
IA: University of San Agustin Phase 1 sponge extracts
• Procured the 600 MHz NMR spectrometer system • Four (4) candidate priority non-toxic active anti-
• Prepared the design and renovation of the NMR proliferative Phase 2 fractions
laboratory and the laboratory standard operating • One candidate priority non-toxic active pro-
procedure apoptotic Phase 1 fraction
• Signed MOAs with TLDCs from Visayas and • One antiproliferative seahorse extract and three (3)
Mindanao anti-migratory seahorse extract
• One (1) bioactive novel sphingolipid isolate and six
(6) bioactive isolates
• One (1) antiproliferative seahorse extract and 3 anti-
migratory seahorse extracts.
42 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 43

Metabolomics-driven Discovery of Antimicrobial Drug Leads from Discovery and Development of Health Products – Marine Component Bridging Efficacy and Safety: IND-enabling Suite of ADMETox Assays
Marine-Sediment Derived Actinomycetes of Iloilo (Phase II) IA: UP Diliman, University of San Agustin, and Pharmalytics Corporation
IA: University of San Agustin IA: UP Diliman Marine Science Institute • Optimized most of its assay protocols for the determination of the physico-
• Identified three (3) lead isolates from marine sediment-derived actinomycetes • Taxonomically described 2 of 3 priority sponges, validated 1 of 3 priority chemical properties, cytotoxicity, plasma stability, and distribution of
for prioritization for further studies in its Phase 2 project, which produced sponge bioactive iterations of the lead compounds
nine (9) antibiotic and anticancer leads • Taxonomically identified 27 out of 28 priority MMOs using their 16S rDNA • Conducted qualitative and quantitative analyses (via LCMS and UHPLC) of
sequence (AOL group) synthetic compounds after cell-based and animal-based assays
Early-Stage Development of Antibiotic and Anticancer Leads from • Successfully harvested the metabolites of 3 out of 4 priority MMOs • Subjected 4 out of 7 compounds for imaging analysis. A total of 595 out of
Philippine Marine Streptomyces • Extracted a total of 28 priority MMOs for their gDNA. PCR amplification of 595 cryosections are ready for analysis through MALDI-MSI.
IA: University of San Agustin their 16S rRNA gene were done for taxonomic identification
• Established the biological and chemical profiles of 13 semi-purified fractions
from one of its 3 lead isolates during the first quarter of its implementation Synthesis and Derivatization of Disease-specific Bioactive Hits and
Lead Compounds (Phase II)
Microwave-Assisted Synthesis, Characterization and Molecular IA: UP Diliman, Mindanao State University - Iligan Institute of Technology, and
Docking Studies of Quinoline-4-Carboxylic Acids and Hydrazide University of Sto. Tomas
IA: UST-Research Center for the Natural and Applied Sciences Studied 1,232 samples for in-silico / molecular docking work and synthesized
• Synthesized a total of six (6) hit 2-substituted quinoline carboxylic acid 354 compounds to date. These are being submitted to the ADMET program for
derivatives in large scale the conduct of the different assays to determine the best drug candidate based
on their physico-chemical, biophysical, and pharmacokinetic properties.
44 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 45

Establishing biorepositories for Philippine medicinal plants will support further

research and their conservation. To maximize the potential of biobanking in the
Philippines, the program aims to set up a central, coordinating network of institutions
that will biobank indigenous medicinal plants and their associated biomaterials from
the country.

The PBN has five (5) component projects under the leadership of Dr. Lourdes
Cardenas in coordination with Prof. Renerio Gentallan, Dr. Elena Catap, Dr. Ma. Anita
Bautista, and Dr. Arturo Lluisma. Specifically, the program aims to:
• Generate and safeguard information on the different levels of appraisal of selected
medicinal plant species with the application of bioinformatics;
• Establish a repository of medicinal plants specimens, namely, seeds, live plants,
extracts, genomic and transcriptomic materials, part of which will be used for
research;
• Maintain propagules from these medicinal plants; d) to develop or adopt standard
operating procedures (SOPs) that support high quality biobank collection and
operations; and
• Serve as the hub of other initiatives and institutions for the extensive and intensive
study of Philippine medicinal plants.

The program established biobanking facilities that can cater live plants, seeds, crude
plant extracts, and the plants’ DNA and RNA. All the information generated by the
four (4) projects would be housed into a single database management system for
easier retrieval of information. The established medicinal plants garden showcases
over 80 species of selected medicinal plants.

The program collected, characterized, and conserved Philippine medicinal plant

genetic resources for the establishment of the seed bank. During the project
implementation, 1,486 accessions of more than 45 medicinal plants were collected

Philippine
from 12 different provinces. About 83% of the total collection is stored in the field and/
or in low-temperature storage while the remaining percentage of the collected plants
were not able to survive. A total of 23 descriptor lists for medicinal plant species
with no descriptor lists were formulated and 253 accessions were characterized in
situ and ex-situ. Using the morphological characterization data, 10 medicinal plant
species were assessed for intraspecies diversity.

Biorepository
The plant extracts/compounds centralized repository housed the extracts and
compounds from 10 plants considered as priorities by the Department of Health
and 14 plants recommended by the private herbal industry collaborators. Chemical
analyses of the plant extracts on their shelf-life and stability that included color

Network
stability and LC-MS & UHLC profiles for a specific period of time were undertaken
and recorded in the database. A database was developed to link all of this information
for accessibility via the laboratory information management system developed for the
PBN Program, and will be linked with the facility’s website (biopex.org.ph).

The program was also able to establish a DNA/RNA bank which currently contains
210 DNA and 206 RNA from the 10 DOH-Recommended plants and the 10 herbal
industry-utilized medicinal plants. These are kept and maintained by the National Dr. Lourdes Cardenas
Institute of Molecular Biology and Biotechnology (NIMBB), UP Diliman. University of the Philippines Los Baños - Institute of Biological Sciences
(UPLB-IBS)
Lastly, the PBN developed a Philippine Medicinal Plant Biobank Data Management
System. Data model implemented in the current data warehouse is useful for
biorepositories of biological samples and extracts/compounds.
46 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 47

Standardized and
Safe Tawa-tawa:
Filling in the Final Gaps for a Clinically-proven
Nutraceutical Product
Dr. Jonel P. Saludes
Center for Natural Drug Discovery and Development (CND3) of the
University of San Agustin and Herbanext Laboratories, Inc.

Tawa-tawa or Euphorbia Hirta L. is believed to have A 10-kilogram batch of effervescent granules

the potential for the treatment of dengue-induced were produced and approximately 2500
thrombocytopenia -- a deficiency in platelets that effervescent tablets were formulated.
increases the risk of bleeding. While tawa-tawa is already
used in folkloric and traditional medicine, there is still a These effervescent tablets were packaged in moisture-
need to develop a standardized commercially available proof containers made of polypropylene (blue) and
tawa-tawa herbal preparation that is backed by evidence. polyethylene (cap) materials. Each tube contained 14
Tawa-tawa effervescent tablets with silica gel desiccant.
Led by Dr. Jonel P. Saludes with co-investigators, Mr. Paul Stability studies were conducted in different storage
Felipe S. Cruz and Ms. Aneline P. Tonolones, the project conditions. The application for certificate of product
aims to develop a nutraceutical effervescent tablet from registration (CPR) has been submitted and filed with the
standard aqueous tawa-tawa extracts that is proven to be Philippine FDA.
safe and potentially effective in increasing thrombocytes
or the platelet count. The project also employed fractionation, chemical profiling
through LC-MS analysis of the tawa-tawa crude extract
Completed last May 31, 2022, the project and putative identification of the compound/s responsible
accomplished nine notable formulations of for anti-thrombocytopenic activity.
laboratory-scale production of tawa-tawa
effervescent tablets with varying percentages Completed last May 31, 2022, the project received
of excipients. One final formulation was sponsorship and funding through the DOST’s Collaborative
selected and was subjected to pilot-scale Research and Development to Leverage Philippine
production. Economy (CRADLE) Program with an approved budget
of Php 4,999,999.00.
48 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 49

Anti-inflammatory
Compound/s from
Select Ferns in
Mindanao Dr. Gina Barbosa
Central Mindanao University

Completed last July 2, 2022, the project evaluated the potential Based on the results obtained, the following generalizations were made: the orthogonal assays suggest potential bioactive fractions.
of frond samples from four select fern species in Mindanao as • The select fern extracts underwent fractionation to separate the extracts into • Putative identities of compounds in bioactive fractions have been determined
sources of anti-inflammatory compounds. various components or fractions, and resulted in a total of 55 fractions. Upon in the dereplication experiments. Dereplication is the rapid identification of
bioactivity determination using enzyme-based assays (COX-2 and 15-LOX known compounds present in a mixture, and is crucial to the fast discovery
In turn, the project may offer scientific basis to pharmaceutical companies and inhibition assay), the crude ethanolic extracts and solvent partitions gave of novel natural products.
natural products research enthusiasts as they carry out drug discovery studies. significant anti-inflammatory activity. Out of 55 fractions, 18 are considered • Isolation of compounds from fractions with potential weight resulted in two
active against 15-LOX enzymes, while 31 fractions are active and selective (2) Liquid chromatography–mass spectrometry (LC-MS) pure isolates.
The team conducted initial anti-inflammatory activity testing in vitro enzyme COX-2 inhibitors.
inhibition of 15-LOX and COX enzymes. Toxicity of the bioactive fractions • Based on toxicity tests, 30 of 42 bioactive fractions were determined to be The project is part of the CMU-TLDC's thrust to explore the potential of
against kidney, liver, and heart cells were also evaluated, while putative identities non-toxic to liver, kidney, and heart cells, which could help explain or support underutilized fern species within the proximity of the university.
of compounds in bioactive fractions were determined in the dereplication the traditional use of these fern species in the treatment of various diseases.
experiments. • Non-toxic bioactive fractions were subjected for orthogonal assays which
are complementary or confirmatory anti-inflammatory assays. Results of
50 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 51

Discovery and
Development of Health
Products – Marine
Component (Phase II)
Dr. Lilibeth A. Salvador-Reyes
Dr. Arturo O. Lluisma
University of the Philippines Diliman, Marine Science Institute

The Discovery and Development of Health Products – Among the accomplishments of the program to date
Marine Component Program, implemented by the UP include the following:
Marine Science Institute and its collaborating institutions,
is one of the big-ticket projects under the Tuklas Lunas • 2200 venom fractions generated from 22 Conus
Program of the DOST-PCHRD. Commencing its research species
in 2014, the DDHP Marine Program has taken the • 20 chemically characterized bioactive conotoxins, 10
Philippines’ high marine biodiversity to their advantage of which to be submitted for invention
focusing on the development of anti-pain and anti- • disclosure and technology transfer to potential
neurodegeneration, as well as anti-infective and anti- partners
cancer drug candidates, particularly from the Conoidean • One patent grant filed for a Somatostatin-like peptide
venom peptides and sponge-associated microbial natural from Conus rolani (Consomatin Ro1)
products respectively. • Ongoing renovation for 1 cell culture facility to develop
cell-based ion channel assays.
The second phase will build on the accomplishments of • Chemical library of 4,274 extracts and fractions and 112
the first phase to further advance marine drug discovery marine-derived pure compounds
efforts in the country. In particular, the program will pursue • 2,832 marine microorganisms in microbial biobank
further characterization and development of promising • Established a medium scale open-sea mariculture and
compounds discovered in Phase 1; significantly increase a flow through aquaria system for marine sponges
the current pool of novel compounds for screening, scale •
up the screening effort, and capitalize on new assay
technologies and approaches to enhance detection of
range of bioactivities; and further develop the Program’s
capability and infrastructure to undertake more efficient,
effective, productive, and sustained drug discovery and
development campaigns.
52 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 53

FUNCTIONAL
FOODS T he Functional Foods Program focuses on research tackling crops and food products that have
possible health advantages beyond their distinctive nutritional benefits for the prevention of
non-communicable diseases. This year, the program monitored two projects for completion, four
ongoing projects, and eight newly approved projects. Aside from R&D, a major initiative under the
program was the spearheading of the development of the Guidelines for Functional Food Claims.

In the coming years, the Functional Foods Program is expected to put focus on enriching research
on crops under the program’s priority commodities, particularly, those lacking initial studies or
with limited data. In addition, the program is expected to have further collaborations in 2023,
strengthening local and international ties for the enhancement of the program.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

DOST
8
NEWLY-APPROVED
NEWLY-APPROVED
PhP 10,380,853.06

2 COMPLETED
19COMPLETED
4 NEWLY-IMPLEMENTED

26 7 NEWLY-IMPLEMENTED
PROPOSALS PROCESSED

PCHRD
PhP 11,041,270.47
54 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 55

Health benefits
of wines
produced from
seaweeds
Prof. Hilario S. Taberna, Jr.
Iloilo Science and Technology University

Despite initial studies on the possible health benefits in the seaweeds and their concentration in the samples
of wines produced from Philippine seaweeds, these (spectrophotometry). The test provided information on the
commodities continue to be underutilized and have little total phenolic content, total flavonoid content, total tannin
commercial value. content, and total antioxidant capacity.

To encourage the use of seaweeds in the production of Following this, the fermentation and production of wines
food products, a project by Prof. Hilario S. Taberna, Jr. of were conducted. The wines are also set to undergo the
the Iloilo Science and Technology University explores the phytochemical screening and spectrophotometry. The
potential health benefits and safety of wines produced project is in support of the initiative of the provincial and
from green, brown and red seaweeds sourced from municipal local government units of Northern Iloilo to
Northern Iloilo. bolster the seaweed industry, as well as to provide food
products that are beneficial to the health of consumers.
The team’s activities in 2022 included the analysis of the Bioactive peptides draw a lot of attention in the scientific
bioactive chemicals present (phytochemical screening) community due to their multiple functionalities. They can
56 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 57

CRADLE Projects

Discovering Liquid Gold from Turmeric Safe Lactic Acid Bacteria (LAB)-based Moringa oleifera-based Developed (MOD) The Cocoa-loca Project: Development of
Mr. Paul Felipe S. Cruz Biofunctional Health-promoting Product as Nutraceutical Product: Nutritional and functional food products and ingredients
Herbanext Laboratories, Inc. an Adjunct Intervention for the Management Metabolome Profiling from cocoa bean shell waste
of HIV-associated Metabolic Complications Dr. Gladys Cherisse J. Completo Dr. Sheba Mae M. Duque
Although many products on the market contain Dr. Marilen P. Balolong University of the Philippines Los Baños University of the Philippines Los Baños
standardized curcuminoids or antioxidant compounds University of the Philippines- Manila
derived from turmeric, little work has been done to Aiming to increase the competitiveness of Philippine Cocoa bean shells (CBS) are often discarded during the
characterize bioactive, water-soluble compounds in The use of functional foods to reestablish intestinal Moringa-based food products, the project probes the chocolate production process. To make use of these waste
turmeric such as turmerin and beta-turmerin. To address function may possibly help in managing complications production of high-quality standardized Moringa spray- products, this study will explore the possible functional
this research gap, this study will develop a spray-dried, among patients with HIV. To study this, the project aims to dried leaves as an ingredient. food products using CBS.
water-soluble turmeric extract that can be used in the develop a Lactic Acid Bacteria (LAB)-based biofunctional
commercial production of functional foods. health-promoting product and evaluate it as a possible This year, 23 compounds were presumptively identified in The project aims to utilize the CBS wastes generated during
adjunct therapy for the management of HIV patients with the extracted Moringa samples and metabolomic studies chocolate processing in the production of functional food
Conducted in Herbanext Laboratories, Inc. in Bago City, metabolic complications. on samples from eight out of 11 sampling sites were also products and ingredients. Specifically, the project will look
Western Visayas, the project was implemented from conducted and reported. into the effects of roasting conditions on the antioxidant
6 January 2020 to 5 January 2022. The project team In 2022, the research team performed cytotoxicity tests properties and fiber contents of CBS wastes, assess the
developed a functional ingredient from turmeric aqueous against normal cells or tests evaluating the toxicity of the The effort is expected to become a catalyst of combined prebiotic potential and functional properties of energy
and ethanolic extracts that demonstrated in vivo anti- LAB strains to normal cells. Antimicrobial properties of the efforts among the agricultural, food production, and bars enriched with CBS powder, and utilize CBS as a
inflammatory activity in animal models and in vitro samples were also studied through agar diffusion assay health sectors in designing effective interventions for source of antioxidants and dietary fiber for chocolate drink
antioxidant potential. experiments, specifically for probiotic inhibition properties Filipinos using products from Moringa oleifera. This study production.
against gastrointestinal pathogens. Preparation of the will also be a significant contribution to address the
The standardized ingredient is used in the creation of a functional food product was also initiated. need for “impactful, and socially and culturally mindful In 2022, currently, the team has obtained data on the
Turmeric latte product in powder form, which was featured programs and policies” (FNRI, 2019) as a solution to the antioxidant properties of CBS wastes as affected by
during the 2022 National Science and Technology Week. After the completion of this project, HIV specialists who persistent problem of under- and over- nutrition and its different roasting conditions. Moving forward, the study is
Using the standardized extracts generated by the project, prescribe adjunctive therapy, HIV patients, patients with co-morbidities in the Philippines. set to determine the prebiotic potential of the samples and
turmeric products with science-based health benefits can metabolic complications, and Filipino researchers who optimize parameters for the extraction of antioxidants and
be produced and brought to the market. The product is are passionate about functional food research will benefit soluble fiber from the CBS.
ready for technology adoption and FDA registration. from its results and output.
58 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 59

Isolation and
Characterization
of Bioactive
Peptides from
Coconut Fruit
Mr. Saul M. Rojas
Isabela State University

be derived from protein rich foods such as coconut fruit. enterica JCM 1651. The samples also showed antioxidant
To further study the benefits of the coconut fruit, Mr. Saul properties.
M. Rojas and his team from the Isabela State University
conducted research isolating bioactive peptides from In addition to its potential health benefits, the potential
coconut meat and evaluating antimicrobial, antioxidant, of the samples as a food preservative agent was also
blood pressure regulating properties. evaluated by meat preservation testing. Results showed
that the peptides were able to gradually slow microbial
growth in ground meat for more than 10 days.
Following the extraction of proteins from the coconut
meat samples, the peptides were purified and tested for
bioactivity. The samples exhibited activity against the
Bacillus subtilis ATCC 6633, Pseudomonas aeruginosa
ATCC 9027, Escherichia coli ATCC 8739, and Salmonella
60 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 61

NUTRITION AND T he Nutrition and Food Safety Program seeks to address the human nutrition problems in the
country such as micronutrient and macronutrient deficiencies, overnutrition, nutrition related
diseases, as well as the current and emerging issues in food safety. The program aims to explore

FOOD SAFETY
avenues and opportunities using science, technology, and innovation in providing solutions for the
improvement of Filipinos’ health through proper nutrition and safe food.

The program was officially launched as one of the new priority program areas under the R&D
Management in March 2022 and received a total of 17 proposals during the 2022 Call for Proposals.
Possible collaboration with the industry on nutrition research, especially on geriatric nutrition and
plant- based diet, was initiated this year.

Integration of nutrition and food safety trends and monitoring of research gaps in nutrition related
diseases and food safety issues that have not been well explored will be the focus of the program
in 2023, alongside the strengthening of local and international collaborations.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 6,921,041.98
5 NEWLY-APPROVED
0 COMPLETED
19 COMPLETED
12 NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
17 PROPOSALS PROCESSED

DOST
PhP 10,380,853.06
62 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 63

Healthy Aging
Program
for Pinoy
(HAPPY)
In the last ten years, the majority of nutrition efforts
tend to be directed towards the prevention of non-
communicable diseases, school children, pregnant and
lactating women, and infants. However, nutrition also
Ms. Hazel T. Lat plays a significant role in ensuring the overall wellbeing
Food and Nutrition Research Institute, Department of of the elderly.
Science and Technology
With four component projects, this program aims
to conduct an aging-sensitive fundamental research
in nutrition epidemiology and physiology, generate
a technology for the development of potential
food products utilizing functional ingredients and/
or compounds that may be beneficial for the aging
population, develop innovative protein food products
for the aged, and lastly, determine the effect of FNRI-
developed products to selected health and nutrition
outcomes of older persons.

In 2022, HAPPY’s Project 1 component established

a Nutrition and Physiology Laboratory housed at the
DOST-FNRI. The facility aims to cater to the needs of
researchers as well as academic professionals who
wish to conduct aging studies using advanced scientific
equipment to measure nutrition-related outcomes
such as body composition, basal metabolic rate, and
functional status.

The project has also completed its data collection

in selected study sites where information on the
demographic profile of the elderly, nutrition, quality of
life, among others were gathered. Projects 2 and 3 were
initiated in September 2022 through which the team
will develop innovative food products for the elderly
and evaluate its effects on the nutrition and functional
status of pre-frail older persons, respectively. Project 4,
meanwhile, is set to start once results from Project 2 are
obtained.
64 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 65

Characterization of Buffalo Milk Assessment of Trans-fat Content in Selected

Oligosaccharide Supplement (BMOS) Processed Food
Extracted from Buffalo Kesong Puti Whey Ms. Rosemarie Dumag
By-Products and Elucidation of its Growth- Food and Nutrition Research Institute
Promoting Effects in Stunting Mice Models
Dr. Gladys Cherisse J. Completo Various literature has established that trans fatty acids
University of the Philippines Los Banos (TFA) substantially increases people’s risk of coronary
heart diseases. Other studies have also reported that TFA
According to studies, stunting or impaired growth among can increase the risk of Alzheimer’s disease and certain
children is associated with irreversible health problems cancers, and worsen insulin sensitivity thereby increasing
later in life. Interventions to stunting are often limited the risk of type 2 diabetes.
to nutrient refeeding, however, this fails to address the
deeper cause of the problem. To guide consumers, a project led by Ms. Rosemarie
Dumag of the DOST-FNRI in collaboration with the World
Recent studies, however, show that oligosaccharides, Health Organization (WHO) assessed the trans-fatty acid
a type of carbohydrate usually found in plant foods, can levels of industry-produced commonly consumed foods.
improve growth through its potential to improve gut
health. This project aims to utilize buffalo (Bubalus Bubalis Currently, the project has already completed the trans-fatty
L) kesong puti whey by-products as a potential source acid analysis of all the samples and the team is currently
of high-value food supplement and study its growth- waiting for the feedback of the WHO regarding the results.
promoting effects. The study is the first to use stunted
mice models colonized with human microbiota by a
stunted Filipino infant fecal donor.

In 2022, the project has completed the profiling of

six breeds of buffalo milk in all lactation stages. The
macronutrients present in colostrum or the first milk
produced during pregnancy and mature milk from six
Philippine buffalo breeds were also analyzed. The team
also performed the optimization of the extraction methods
of the Buffalo Milk Oligosaccharide Supplement (BMOS)
and purified oligosaccharides (OS) from whey, as well as
the identification and quantification of the compounds
present in the BMOS OS.

The team is set to complete the BMOS production by

the end of 2022 and conduct the in vivo experiments in
2023. The project is implemented in collaboration with
Philippine Carabao Center, Philippine Genome Center,
National Institute of Molecular Biology and Biotechnology,
and Pascual Pharma Corp.
66 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 67

Research Center
for Rehabilitation/
Sports Medicine
(Oplan ATletang
Pinoy)
Dr. Consuelo Gonzalez-Suarez
University of Santo Tomas

The recent success of Filipino Oplan ATP aims to develop a wearable measuring muscle response upon
athletes in international competitions sensor that analyzes joint angles and stimulation. The project also explored
serves as a testament to the athletic muscle activities, develop a protocol streamlining the process of ultrasound
talents of Filipinos. Putting a premium for the preparation of platelet rich imaging and conceptualized
on sports, medicine and research plasma which is used by athletes to methods to analyze ultrasound
is necessary to further improve promote recovery of injuries, and to images via different image processing
their performance by providing our develop a software application that techniques. Studies on platelet-rich
athletes with scientific training. determine the lateral displacement of plasma, its preparation, availability,
the patellar tendon in patellofemoral components, and usefulness were
The Oplan ATletang Pinoy (ATP) pain syndrome. also conducted.
Program, led by Dr. Consuelo
Gonzalez-Suarez of the University of The team studied existing literature The program is implemented in
Santo Tomas aims to establish the on techniques used in performing collaboration with University of Santo
Research Center for Rehabilitation/ ultrasounds used by athletes to Tomas Hospital, Philippine Sports
Sports Medicine which will facilitate diagnose injuries, kinematic analysis Commission, and Colegio de San
research to improve athletic or the study of the motion of the Juan de Letran.
performance. human body, and EMG activation or
68 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 69

MENTAL HEALTH W ith the passing of the Mental Health Act last 2018, the National Mental Health Research Agenda was launched
to address the needed mental health research and innovation in the country. Guided by the three outcome-
based themes of the Agenda, which are: (1) Improved Mental Health Information System; (2) Strengthened Leadership
and Governance; and (3) Accessible, Affordable, Responsive, and Holistic Mental Health Services; the Mental Health
R&D Program aims to support research on providing quality, relevant, effective, innovative, and culture and gender
inclusive mental health R&D innovations to the country.

The MH R&D Program will support the following areas in 2023:

• Risk Factors and Treatment/ Therapy of Mental Health Disorders and Psychosocial Problems.
• Inventory of Mental Health Services including Mental Health Literacy
• Information and Communication Technology for Mental Health including Social Determinants of Mental Health
related to Technology
• OMICS Technologies Application for Mental Health
• Brain Mapping
• Neurological, Neuropsychiatric, and Neurodevelopmental Conditions

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD

7 NEWLY-APPROVED
NEWLY-APPROVED
PhP 11M

12 COMPLETED
19 COMPLETED
4 NEWLY-IMPLEMENTED
7
16 PROPOSALS
NEWLY-IMPLEMENTED
PROCESSED

DOST
PhP 23M
70 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 71

Acceptability of Telepsychiatry among Overseas

Filipino Workers in Kuwait
Mr. Gregorio Candelario, Jr.
Southern Philippines Medical Center

Completed in 2022, the project determined the acceptability of

telepsychiatry consultation among OFWs in Kuwait Overseas
Workers Welfare Administration (OWWA) facility. The project
catered to a total of 54 participants, all female with an average age
of 35. The most common significant diagnosis was Acute Stress
Disorder, followed by Major Depressive Disorder. The results
of the questionnaire revealed to be 4.74 out of 5, which means
that the participants strongly agree with the positive statements
pertaining to the use of telepsychiatry.

The project was awarded 1st Place for the Best Poster Presentation
out of 34 entries in the 53rd Asia Pacific Academic Consortium
for Public Health Conference in partnership with the University of
the Philippines Manila - College of Public Health (host) held on
22 - 23 September 2022 at the Marriott Grand Ballroom, Pasay
City, Philippines.

The project plans on expanding its activities to other identified

hotspots by the OWWA, such as Saudi Arabia and Hong Kong,
and currently looks for collaborators for the sustainability of the
project for possible private companies who are willing to employ
the displaced OFWs upon their return in the Philippines.
72 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 73

Novel Approaches to Treatment of Addiction and

Depression (NATAD) using Animal Models
Dr. Rohani Cena-Navarro
University of the Philippines Manila

The program is one of the first research endeavors in the

Philippines focused on the neuroscience of drug addiction,
specifically with volatile inhalants such as toluene. With two
components, the program aims to test novel pharmacological
and behavioral treatments for overcoming toluene withdrawal
and craving in a rodent model and assess the pharmacokinetic
and pharmacodynamic interactions of selected psychobiotics
and antidepressant drugs in the depression-like rat model.

In 2022, the team developed a rat model of adolescent toluene

addiction and withdrawal that mirrors inhalant use in the
Patterns of Detection and Treatment of Psychosocial Interventions used by Mental Philippines and will assess the effects of toluene withdrawal
Mental and Behavioral Disorders among Health Professionals among in-patients of and craving on rats’ memory, anxiety, and social interaction. The
OFWs tertiary hospitals referred for psychosocial project will essentially support rehabilitation research and policies
Dr. Veronica E. Ramirez problems to address the toluene addiction of adolescents in the country.
University of Asia & the Pacific Dr. Cynthia Leynes Project 2 of the NATAD Program was approved for funding on 31
Cardinal Santos Medical Center January 2022. Led by Mr. Bryan Paul I. Bulatao, this project aims
to determine and compare the antidepressant effect of selected
Most OFW patients experienced panic attacks, The project aims to describe mental health problems seen psychobiotics and antidepressant drugs in their combinations in
schizophrenia, paranoia, anxiety, and extreme fear due among in-patients in tertiary hospitals and the treatment rat models, which is obtaining information about a disease and its
to the COVID-19 pandemic. This occurred either in their strategies used to manage these problems. The project prevention, diagnosis, and treatment using an animal.
country of work, while in hotel quarantine during their ended on July 31, 2022.
return to the Philippines, or during their reintegration in
their respective communities. Mental health problems In July 2022, a face-to-face closing meeting was held to
have different levels, ranging from temporary behavioral discuss the results of the study. The project completed all Fully Automated Conversational Agents
disorders to severe mental disorders. Therefore, the data collections in the Chart Review, Surveys, KIIs, and (Chatbots) for Enhancing Public Mental Health
treatment of mental health problems varies in degree of FGDs. The project also published the booklets: “Treatment Dr. Ronald Del Castillo
difficulty and distress. Recommended actions should not Recommendations for Psychosocial Interventions for
be “one size fits all.” Referred In Patients” and “Mental Health Services for This project aims to develop and test the effectiveness of fully
Psychosocial Interventions.” automated conversational agents or chatbots in promoting
The project analyzed the patterns of detection and mental well-being and reducing psychological distress. In 2022,
treatment of mental and behavioral disorders among The project’s end products will serve as a guideline for the project team conducted the initial development of the DarS
OFWs and derive from the findings the implications to the management of psychosocial problems of patients mobile app prototype including the wireframe, infrastructure,
psychosocial support services. admitted in tertiary hospitals referred for psychosocial design and development, and started working on the improvement
problems and will serve as a list of resources in the of its usability and acceptability for testing.
Completed in July 2022, among the recommendations community that may be utilized for the aftercare of patients
of the project is the development and publication of the admitted to tertiary hospitals referred for psychosocial
Manual on Mental Health Interventions and Psychosocial problems.
Support for Filipino Migrant Workers in four languages
(English, Tagalog, Bisaya, Ilokano) and in three versions:
printed, PDF, and web-based. This will provide information
on mental health interventions and psychosocial support
for Filipino migrant workers. This will also support the RA
11036 Mental Health Act that will enhance the delivery
of integrating mental health services, promoting and
protecting the rights of persons utilizing psychiatric,
neurologic, and psychosocial health services.
74 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 75

Roundtable Discussions on Spirituality and A Public Forum: Spirituality in the Among the resource speakers who gave technical presentations The webinar, with the aim of disseminating the National Mental
Mental Health Research in the Philippines Philippine Mental Health Research on the subject were Dr. Michael Tan, Professor Emeritus in Health Research Agenda 2019 - 2022 (NMHRA) and imparting
and Practice Anthropology at the University of the Philippines – Diliman; to the proponents the skills and knowledge needed to develop
Sister Mary John Mananzan, Vice President for External Affairs a significant and high-quality research proposal in preparation
Spirituality is a recent dimension in the already existing Researchers, practitioners, mental health care providers, and
at St. Scholastica’s College; Dr. Ma. Lourdes “Honey” Carandang, for future call for proposals, was attended virtually by a total
biopsychosocial framework. This topic, however, is not representatives of religious groups attended the Spirituality
Clinical Psychologist and Founder of the Mindfulness, Love, and of 95 participants from all over the country. Participants were
part of the recent National Mental Health Research Agenda in the Philippine Mental Health Research and Practice public
Compassion Institute for Psychosocial Services, Inc.; and Dr. provided copies of the Mental Health Research Manual and the
(NMHRA) hence part of the goal of this activity was to forum led by the Department of Science and Technology -
Allan Bernardo, a Distinguished University Professor at De La NMHRA.
identify which aspects of religiosity and spirituality would Philippine Council for Health Research and Development
Salle University – Manila.
be particularly relevant to mental health research in the (DOST-PCHRD) on December 14, 2022 at the Philippine
Philippines and also to incorporate spirituality and mental International Convention Center, Pasay City. S&T Features
Also present in the gathering were members of PCHRD MH-
health in the NMHRA.
RAG who are also experts in the field of mental health, along In celebration of Mental Health week, the Mental Health R&D
The goal of the gathering is to communicate the results
with Professor Emeritus Dr. Lourdes Ignacio, Dr. Arsenio Alianan Program was featured as the pilot episode for the S&T Features
Three roundtable discussions (RTDs) were held — the first of the roundtable discussions (RTDs) conducted in 2021,
Jr., and Dr. Carl Abelardo Antonio. last 25 October 2022 entitled, “Mental Health is our Agenda.”
was with persons of faith, the second was with professionals with various leaders of faith-based groups and researchers
The S&T Features is an online show which aims to promote
(psychologists, psychiatrists, sociologists, health practitioners, who discussed spirituality as part of research, therapy and
In conclusion, Dr. Ignacio encouraged mental health researchers the S&T Fellows Program of the DOST by showcasing the
academe), and the last was an RTD with researchers and recovery of people with mental conditions. The RTDs also
to submit proposals in line with the NMHRA to help develop accomplishments and in volvements of the S&T Fellows in their
members of the academe. Data from the RTDs were aim to know the spiritual methods that can help prevent
evidence-based ideas and further grow the mental health R&D respective DOST agencies.
synthesized, and the results were presented in a public forum. these conditions.
program in the country.
Through this episode, S&T Fellow Dr. Sarah Jane Jimenez,
The series of RTDs were part of the DOST-PCHRD’s support
Seventy-six people attended the gathering at PICC, while more together with the Program Head Mr. Jules Celebrado, and
to the Philippine Council for Mental Health (PCMH) goal
than three hundred attended the live broadcast on Zoom, and Mental Health Research Advisory Group member Dr. Arsenio
of introducing the biopsychosocial spiritual framework that
almost 1,700 watched the Facebook livestream. Alianan Jr. shared to the public why mental health research is
provided a scientific perspective in adding spirituality to the
vital to the improvement of the mental health situation in the
new dimension of Mental Health.
Mental Health Research Manual Capacity country. The team also showcased the various mental health
Building research projects being supported by PCHRD, and its current
The forum also presented research topics related to spirituality
and future impact on society.
that will be included in the National Mental Health Research
On 28 October 2022, the Council, in cooperation with the
Agenda (NMHRA), with hopes that the study under this will
Mental Health Research Advisory Group and Technical Working The said program aims to engage the services of highly qualified
help improve policies and improve health care services in the
Group conducted the capacity building webinar on Mental researchers, scientists, and engineers in various DOST R&D
Philippines, as well as around the world.
Health Research entitled, “GABAY: MH Research Philippines: Institutes and Councils to increase and strengthen the human
Guidelines And Building Quality Mental Health Research in the resource complement of the Department’s R&D group.
Philippines.”
76 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 77

T he Disaster Risk Reduction and Climate Change Adaptation in Health (DRR-CCAH) Program aims to develop

DISASTER RISK REDUCTION

technologies that address and/or prevent health effects from disasters and climate change leading towards a
more resilient Philippines. It also focuses on the reduction of health risks and consequences of health emergencies
which is fundamentally vital in attaining health security and building the resilience of communities, country, and

AND CLIMATE CHANGE

health systems.

This program is essential in safeguarding development and implementation of concrete actions ensuring the

ADAPTATION IN HEALTH
development gains enumerated in the Sendai Framework to which the Philippines, a nation highly vulnerable to
natural disasters and climatic hazards, is one of the signatory countries.

Scientific and technological activities and innovations in the DRR-CCA in Health Program are part of the priorities of
the government with the aim to address the following gaps:

• Identification and characterization of climate-sensitive and/or climate-related diseases;

• Food security and nutrition during disasters especially for the vulnerable populations; and
• S&T based innovations in building resilient health systems during disasters

For the year 2023, the DRR-CCAH R&D Program expects some ongoing projects to be completed and four projects
to commence. Further, the program expects to receive more proposals aligned with its priorities since there will be a
series of caravan, and stakeholder engagements to be conducted.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

4 NEWLY-APPROVED
NEWLY-APPROVED

2 COMPLETED
19 COMPLETED
2 ONGOING
7 NEWLY-IMPLEMENTED
18 PROPOSALS PROCESSED

Php 7,297,587.75 (PCHRD)

78 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 79

The Aytas of Mt.

Pinatubo as Models
for Climate Change
Resilience Professor Leonardo Estacio Jr.
Addictus Research and Intervention Center Inc.
80 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 81

The Aytas of Mt. Pinatubo as Models for Determining Provincial Health Risk to
Climate Change Resilience Climate and Disasters in the Philippines
Professor Leonardo Estacio Jr. Dr. John Q. Wong
Addictus Research and Intervention Center Inc. EpiMetrics

It has been observed that indigenous knowledge systems Extreme weather conditions have a significant impact
and practices (IKSPs) allow indigenous people (IP) during on health, especially for infectious diseases in vulnerable
disasters to survive and bounce back with minimal or even populations, and are dependent on the baseline pathogens
without additional humanitarian aid - thanks to their time- available in the community. Other vulnerabilities, such
tested and effective collective knowledge and practices. as comorbidities, chronic disease, or demographics are
heightened when climate change is present. This research
This study aimed to document and assess the IKSPs on developed and visualized climate and disaster health
climate change resilience of the Ayta Mag-Antsi of Porac risk of nine Philippine provinces and all cities and one
(Pampanga) and Ayta Sambal of Botolan (Zambales), and, municipality of the National Capital Region (NCR).
thereafter, produce IKSP-based technologies in disaster
risk reduction and health emergencies. Completed in July 2022, the study identified climate-
sensitive diseases, which are among the 48 most
The study completed its implementation on 02 November burdensome diseases in the Philippines. A total of 15
2022. Its major accomplishments include the following: articles showed quality evidence of climate sensitivity
• Thirty-four researchers composed of 26 community- of the 14 diseases. Analysis and modeling assessed the
based researchers from four Ayta communities relationships among 2009-2019 monthly municipal data
and eight researchers from Addictus Research and on climate (temperature, rainfall, humidity, wind speed)
Intervention Center Inc. were trained. and health outcomes, and hotspots of each disease were
• Documented substantively eight IKSPs on climate identified across the provinces.
change resilience that the Ayta peoples possessed
such as natural early warning systems on climate Results also suggested that long-term climatic changes
change, building an emergency shelter from nature, have bigger effects on health than transient or seasonal
ready-to-pick natural foods (edible flora and fauna), changes. This study found out that some of the most severe
storing rainwater and making fire to fight cold and to diseases in the Philippines are impacted by temperature,
cook food, herbal plants and medicines, sustainable humidity, rainfall, wind speed, and vegetation. Results of
agroforestry, enhancing social cohesion and social this study provide a baseline for the relationship between
support system, ritual practices, and worldviews on climate change and health in the Philippines that can be
health emergencies and disaster-related behaviors, used to guide local policies and initiatives, as well as the
among others. country’s Climate Change Adaptation in Health (CCAH)
plan. The shortlisted diseases also provide a research
Based on the data gathered, the research team finalized agenda for climate-sensitive diseases forecasting for the
the IKSP-based technologies and guides applicable most burdensome diseases.
on health emergencies and disaster risk reduction and
management. In addition, two policy briefs related to
recognizing, protecting, and strengthening the IKSPs on
climate change adaptation of the IPs and on developing
and promoting IKSP-based technologies and guides
for climate change adaptation are being prepared for
dissemination to policymakers and program developers.
82 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 83

OMIC
TECHNOLOGIES FOR HEALTH
T he OMIC Technologies for Health Program aims to utilize ‘OMIC’ technology platforms in generating meaningful
information as inputs into the development of personalized/ precision medicines, diagnostics, therapeutics, other
technologies, and as support to health and clinical practice guidelines and policies of the Philippines.

The program recognizes that studying the Filipino Genome will reveal a wealth of information which can lead to
the development of better ways and technologies in disease diagnosis, management, treatment, and prevention.
The knowledge that will be gained from looking into the genes and extending these to different biomolecules (RNA,
proteins, lipids, carbohydrates, etc.) of the Filipino can ultimately lead into the development of better, more personalized
medicines and therapies for optimum, individualized treatment tailored for the Filipinos.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD

17NEWLY-APPROVED
NEWLY-APPROVED
PhP 46,656,085.56

4 COMPLETED
19 COMPLETED
25 NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
25 PROPOSALS PROCESSED

DOST
PhP 273,649,061.18
84 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 85

Cancer-related
LUNG CANCER BREAST CANCER
Clinical Proteomics for Cancer Initiative (CPCI): Gene Expression Profiling of Breast Cancer
A Proteomics-Based Discovery of Non-Small Cell Among Filipinos and Development of Breast
Lung Cancer Biomarkers and Drug Targets in the Cancer Mammosphere Assay Toward

Research
Philippines Individualized Cancer Management
Dr. Herdee Gloriane C. Luna Dr. Rodney B. Dofitas
Lung Center of the Philippines Philippine General Hospital – UP Manila
Dr. Michael C. Velarde - Institute of Biology, UP Diliman

In the Philippines, lung cancer is the major cause of Breast cancer is one of the most common cancers affecting
mortality accounting for 17.2% of cancer- related deaths. women worldwide. In Asia, the Philippines is reported to
Non-small cell lung carcinoma (NSCLC) is the most have the highest incidence of this disease, with an age-
commonly diagnosed form of lung cancer, accounting for standardized rate of 47.7 per 100,000 per year. Despite
approximately 80% of the disease. The high incidence and these concerning numbers, little is known about the
mortality rates of lung cancer, in addition to its remarkable biology of breast cancer. In order to shed light on and help
resistance to common treatment strategies emphasize in the management of this disease, this program explores
the need to better understand the biology of cancer and approaches to cancer characterization and diagnosis
to identify clinically relevant biomarkers that can either geared toward individualized cancer management.
be used for early diagnosis, predict treatment response,
determine the possible course of the disease, or to serve In 2022, the program performed an initial dry-run for
as novel targets for therapies. optimization of core needle biopsy and mastectomy,
transportation of specimens, and optimized the process
This program aims to discover biomarkers and drug targets flow and execution of biospecimen processing. The
for Lung Cancer and acquire TKI resistance, specifically program also started redesigning the Biobank database
for NSCLC in Filipino patients, through proteomic analysis and website to further operate in an ideal set-up. A
- a part of the clinical proteomics field which deals with partnership was also formalized with AVATAMED, a
the quantitative measurement of multiple proteins in a Precision Medicine company in Singapore which enables
biological sample that is related to human disease. the project to exchange facilities, researchers, and
students, in addition to sharing of relevant information,
In 2022, the program continuously assembled clinical materials, and other industry-academia activities.
samples for proteomic studies on NSCLC. The project
also completed enrollment of patients for the Metastatic Currently, the program is set to identify possible gene
Arm of the study (discovery of protein biomarkers for expression profiles that can be used as predictive markers
TKI Resistance) while enrollment for the surgical arm in Filipinos with locoregionally-advanced breast cancer. It
(discovery of protein biomarkers for NSCLC) is ongoing. is expected that by 2023, the program will have initiated
Philippine Health Statistics in 2009 reported cancer as the Also, the program actively conducts specimen collection, the development of a Tumor Profiling Test Kit and 3D Cell
third leading cause of mortality. After a decade, statistics show laboratory procedures for the characterization of patients, Culture Breast Cancer Chemotherapy Testing Panel for an
histological and molecular analysis of patient specimens, individualized therapy and precision medicine for greater
that cancer cases continue to increase in which it became the as well as TKI resistance monitoring and follow-up. survival.
second leading cause of mortality in the country. Data and samples from Project 1 are continuously being
shared/ transferred with/to component Projects 2 and
3 for processing, proteomics analysis and confirmatory
analyses. The project leaders under these program are
• Dr. Eloise I. Prieto-Vasquez - National Institute of
Molecular Biology and Biotechnology, UP Diliman
• Dr. Baby Rorielyn T. Dimayacyac-Esleta - Institute of
Chemistry, UP Diliman
86 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 87

LIVER CANCER Establishing the Integrated Protein Research and Development Center (IPRDC):
A Biotechnology Facility for Health
Early CANcer Detection in the LivEr of Filipinos Dr. Crisanto M. Lopez, Dr. Arni E. Gambe-Gilbuena, Ms. Danielle B. Lapinig, and Dr. Ricardo Jose S. Guerrero
with Chronic Hepatitis B Using AI-Driven Detection Ateneo de Manila University
System (CANDLE Study)
Dr. Beatrice J. Tiangco
University of the Philippines Manila

Around 7 to 10 million Filipinos are Hepatitis B positive and are at high risk of
developing cirrhosis of the liver. If not monitored closely, this eventually leads
to liver cancer, which can still be cured in its early stages through removal of
tumors, but becomes incurable if caught at a later stage.

The CANDLE Study Program aims to improve the healthcare system

concerning liver cancer by establishing a clinical and genomic profile of the
Filipino population for early detection of liver cancer, and developing an Artificial
Intelligence-driven (or AI-driven) detection system for the early diagnosis of liver
cancer among chronic hepatitis B cases.

In 2022, the project recruited most of its target 800 patients through the efforts of
partner hospitals across Luzon, Visayas, and Mindanao. As analysis of genomic
data is performed, the project hopes to identify at least ten genetic variations
contributing to liver cancer diagnosis and prognosis.

Now, in its final year, the project will produce a clinically useful scoring system for
liver cancer diagnosis which can help clinicians decide on how often diagnostic
tests should be done, thus maximizing use of the limited funds of patients while
maintaining good clinical practice. Dr. Ranzivelle Marianne Roxas-Villanueva -of
the University of the Philippines Los Baños is also a project leader under this
program. The program aims to be a Center for Integrated Protein produce enzymes used in RT-qPCR and RT-LAMP based
Research and Development that can potentially offer lower diagnostics at a laboratory scale and demonstration of
priced reagents with comparable functional performance the functional viability of enzymes/proteins produced in-
to commercial kits and reagent components. With house at small scale compared to commercial proteins.
this, components available locally decrease associated On the other hand, majority of Project 2 and 3’s activities
logistical costs and allow more responsive production are ongoing, which are geared towards demonstrating
based on demand. This can also decrease reliance on bulk industrial-scale production of recombinant proteins using
purchasing and storage of inventory. This prevents spoilage E.coli-based expression systems and on the development
as laboratories would only buy what they need at more of hardware compatible with the protocols developed.
affordable prices. Local production of these core proteins
also give the Philippines the ability to develop technology to The project built a prototype of the open-source versions of a
address emerging variants and pathogens. bioreactor and a fast protein liquid chromatography (FPLC)
system geared to improve the production capacity of the
In 2022, the program accomplished most of its targets IPRDC program. Activities to improve these prototypes are
for Year 1. Project 1 completed the majority of its activities also ongoing.
related to the establishment of the center’s capability to
88 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 89

Expanded Capability Building in R&D in Center has also been in the forefront of COVID 19 testing,
Genomics: Establishment of Genomics Genomic surveillance, and research augmentation in the
Consortia and Core Facilities in Mindanao country. On March 11, 2022, the University of the Philippines
and Visayas (UP), through its Philippine Genome Centers (PGCs) in
Dr. Cynthia P. Saloma, PGC Main UP Visayas and in UP Mindanao, announced that it is now
Dr. Victor Emmanuel Ferriols, PGC Visayas capable of sequencing the genome of SARS-CoV-2 from
Dr. Joel Hassan G. Tolentino, PGC Mindanao community samples in both island groups, which was
made possible through the joint efforts of UP, the DOST,
Genomics has been at the core of generating and the Department of Health (DOH), and the Department
translating useful information into actionable results. The of Budget and Management (DBM). The announcement
establishment of the PGC, hosted in UP and supported by was done through an official launching event hosted via
DOST & CHED through research grants, is a government zoom by the Philippine Genome Center in coordination
investment that provides learnings, success stories, and with the Department of Health - Epidemiology Bureau
tangible outcomes towards increasing the capacity of the and PCHRD. In November 2022, PGC Visayas also
country on Genomics research, ultimately for the benefit launched its Bioinformatics Facility, which can now cater
of the Filipinos. In 2018, PGC embarked on expanding its to the bioinformatics needs of researchers in the Visayas.
genomic sequencing capacity in the various regions of
the country through the setting up of the PGC Visayas By the end of its implementation, it is expected that the
Satellite Facility (https://pgc.upv.edu.ph/) and the PGC network, facilities, expertise and other output produced by
Mindanao Satellite Facility (https://pgc.upmin.edu.ph/), the program will continue to be utilized by the Philippine
which was accomplished through this program with Genome Center for Filipino researchers and towards
Vaccine Immune Response and Outcome The project is a ride-on study of the WHO STV, and it funding from the DOST. enhancing the country’s capabilities for OMIC research in
Monitoring with Epitope Sequences aims to design and use synthetic peptide-based antigenic various fields.
(VIROMES): Application to Philippine WHO constructs (SPACs) for immunochemical analysis and to In light of the COVID-19 Pandemic, the Philippine Genome
SOLIDARITY COVID-19 Vaccine Trial characterize antibody responses, including breakthrough
Dr. Salvador Eugenio Caoili infections, among trial participants. The study will also
University of the Philippines Manila look into the complement system and T-cell responses
of participants who develop symptoms, in an effort to
The WHO Solidarity Trial Vaccines is a large international, better understand the mechanisms and circumstances
double-blind, placebo-controlled, randomized clinical underlying the ineffectiveness of vaccination against
trial that aims to coordinate the prompt, efficient, and SARS-CoV-2 infection.
reliable evaluation of candidate COVID-19 vaccines under
development. The workflow will yield blood derivatives In 2022, a total of 125 people gave their consent, and 882
(i.e., serum and plasma) that contain antibodies, which can samples were collected for the study. Additionally, peptide
be examined to detect antibodies that recognize SARS- sequences for the immunoassay have been produced. It is
CoV-2 epitopes and other relevant antigens that may be anticipated that participant recruitment, laboratory work,
present in the candidate vaccines. Such analyses could and data processing will continue until the third quarter
reveal differences in epitope recognition profiles between of 2023.
the vaccinated and unvaccinated, as well as participants
receiving different vaccines in the trial. Moreover, the The information gained from the study will help guide
products of RT-PCR testing from COVID-19-confirmed efforts for the effective development and distribution of
symptomatic cases provide specimens for sequencing COVID-19 vaccines, particularly for the Filipino community.
of SARS-CoV-2 which allows better characterization Additionally, this study would help build up local capacity
of antibody responses among study participants with to better handle the ongoing threat posed by emerging
breakthrough infection. and re-emerging infectious diseases.
90 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 91

Philippine Program for Diagnostic Biomarkers, Disease Modeling

and Nutraceutical Product Development (PhilDIAMOND):
Initial Focus on HIV-
related Neurocognitive and
Metabolic Complications
Dr. Marissa M. Alejandria
University of the Philippines Manila

The Philippines, in recent years, is experiencing one of the complications in our country. with partner institutions, the project envisions strengthening the at Cambridge, United Kingdom hosted by StemCell Technologies.
fastest-growing HIV epidemics in the world. With the provision disease-modeling research capacity of the Philippines.
of the now more accessible antiretroviral therapy (ART) to HIV- In 2022, Project 1 established a fully-functioning Flow Cytometry Project 3 will develop a probiotic-based nutraceutical product
positive patients, HIV can now be considered a manageable Core Laboratory in UP Manila that will be utilized by other Project 2 completed the establishment and development for potential adjunct therapy of HIV-related complications.
disease and patients can now live a near-normal lifespan. researchers, as well as other DOST-funded programs such as of Mammalian Cell Culture Laboratory-Stem Cell In Vitro
However, ART cannot fully eradicate the virus in various sites the UP Manila MORPH Program and IMMUNE Program. With Applications in Research and Modeling (MCCL-SCIARM) in Ultimately, the findings can provide possible recommendations
(i.e., brain, bone marrow, lymph nodes, and gut), which leads to the continuous support of DOST-PCHRD to MD-PhD scholars UP Diliman. A satellite disease modeling laboratory is being for the standard of care for people living with HIV which could
a continuous cycle of inflammation and failure of the immune in the UP College of Medicine, this project also provides an developed at the Mindanao State University - Iligan Institute be made in terms of screening for neurocognitive impairment,
system. avenue for them to join this project as fulfillment of the partial of Technology (MSU-IIT) in Iligan City. The project team also as well as monitoring of immune dysfunction levels. The project
requirement for their research course work. conducted various inter-program training and workshops leaders under the program areDr. Ahmad Reza F. Mazahery - of
Project 1 proposes an innovation for molecular mechanistic on flow cytometry, disease modeling, cell culture, and natural the Institute of Biology, UP Diliman, Dr. Marilen P. Balolong of UP
research in HIV immunology through investigating the role of Meanwhile, Project 2 aims to help improve the efforts of product extraction. The project also completed the training of Manila, and Dr. Leslie Michelle M. Dalmacio also from UP Manila.
the immune dysfunction markers in the development of HIV personalized medicine in the country. Through collaborations personnel for induced pluripotent stem cells (iPSCs) generation
92 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 93

Projects ZOOTRIP: Zoonotic Transmission of Intestinal

Parasites
Cellular Immunity and Resistance to
Schistosomiasis in the Philippines (CRISTAL
Using Genomics to Improve Diagnostics
for Tuberculosis in the Philippines (THPR

under
Dr. Vachel Gay Paller Project) Project)
University of the Philippines Los Banos Dr. Mario Antonio L. Jiz II Dr. Mari Rose A. De Los Reyes
Research Institute of Tropical Medicine Research Institute of Tropical Medicine

Newton
In the Philippines, intestinal worm infection—remains highly
prevalent, especially in rural and poor urban communities. Schistosomiasis currently infects over 200 million people With the advancement of molecular techniques, rapid
The infection spreads through contact with water bodies worldwide. Notably, the infection caused by the Philippine molecular tests have recently become available for the
contaminated with the worm larvae emerging from snail hosts. strain of S. japonicum (SjP), one of the five blood fluke diagnosis of TB. Among these is Xpert, however, it relies

Agham
This shows that the environment and animals play a significant species causing the disease, does not exhibit a similar on sputum samples which is generally a challenge for
role in the spread of intestinal helminths to humans. However, pattern of a distinct age-peak at adolescence as seen with some populations who have difficulty or cannot produce
the contribution of zoonotic transmission to the overall burden other strains. The prevalence of SjP remains high even in it. This project will develop transcriptomic signatures of TB

Cycle 2
of human intestinal worm infection and the relative importance older populations and amongst males. patients into a risk score protocol that could be utilized
of different animal and environmental reservoirs remains poorly clinically to identify active TB and evaluate treatment
understood. No previous studies have investigated the role of Tfh response in reducing active TB.
and Tfr cells in schistosomiasis and the new information
This project is an interdisciplinary study that combines gained from this study will be of importance to combat The THPR project has completed its training for the
human, animal, and environmental elements with molecular this disease in the Philippines. healthcare workers of the RITM and already exceeded the
diagnostics, genomics, and mathematical modeling to look into overall enrollment number for Category I - Adult (33/30),
and assess the dynamics of helminth infection transmission in The CRISTAL project has completed its three study visits to MDR (31/30), and non-TB patients (51/50). Among the
the Philippines as well as to identify effective and sustainable Palo, Leyte, its enrollment of participants, sample collection, culture isolates, 32 have been found to be drug resistant in
parasite control and elimination strategies in endemic areas. reinfection assessment, upgraded equipment and trained which 20 have multidrug resistance, four have extensive
staff in both the RITM and its satellite laboratory in Palo, drug resistance, six have mono-resistance, and two have
In 2022, the team was able to complete the fieldwork in Leyte. Despite the ongoing pandemic, the project had an poly-resistance. The project had been able to establish
Caraga and compile the list of parasites recovered in the average of 95% sample submission compliance from its partnerships with the Philippine Children’s Medical Center
region. Household surveys, key informant interviews (KII), and participants, these samples are currently being shipped and Philippine Children’s Hospital and had been able to
risk assessments were conducted in order to determine and to their collaborators in London School of Hygiene and develop an online dashboard to easily monitor the status
understand the burden of disease associated with zoonotic Tropical Medicine for analysis. of patient enrollment and recruitment, as well as the
parasites in the human population and the measures identified current number of MTB isolates and blood samples.
to reduce the burden. The genome sequencing from helminth- The project also developed a heat map of the Schistosoma
positive samples collected during field sampling was done by japonicum hotspots in Brgy. Macanip, Jaro, Leyte using The project was also able to upgrade and provide
the UK partner, University of Surrey. In terms of capacity building, the stool screening data from the study. In addition, the equipment to the National Tuberculosis Reference
the group held a number of training sessions for nurses and project had presentations in the Newton Agham Virtual Laboratory and Molecular Biology Laboratory of the RITM.
medical technologists on how to correctly identify parasites Grants Gallery of the British Embassy Manila, DOH SCEP In addition, the project recently had a poster presentation
found in human feces. There were also training seminars on Schistosomiasis Stakeholders Forum, and RITM 40th in the Newton Agham Virtual Grants Gallery of the British
molecular methods, bioinformatics, and socio-economic Anniversary Research Forum. The results of this project Embassy Manila. The results of this project are expected
analysis for the enumerators, research assistants, and students. are envisioned to provide a better understanding of the to be of benefit to the field of diagnostic and genomic
immune response and will inform the future development research of MTB not only in the country, but globally.
This project will benefit stakeholders, particularly in poor and of vaccines.
marginalized communities, will increase their awareness of
intestinal helminths, and provide a better road-to-health for
such activated communities. The project findings will also
enable the development of novel control strategies, leading to
increased effectiveness and sustainability of intestinal worm
control in the Philippines, and ultimately to improvements in
health in endemic areas. The assessment of socio-economic
impacts of intestinal helminths in humans, animals, and the
environment will provide crucial evidence for policy makers
and funders.
94 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 95

DIAGNOSTICS U nder the Diagnostics Program, the DOST-PCHRD invests in the development of rapid, cost-effective, and
minimally invasive diagnostic kits/ devices/ tools/ tests for early detection and monitoring of communicable,
non-communicable, and neglected tropical diseases in the Philippines. The program also credits the utilization of
current and/ or novel technologies to improve and/ or validate existing diagnostic kits, tests, and devices.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 51,881,436.40
9 NEWLY-APPROVED
19 COMPLETED
19 COMPLETED
22 NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
14 PROPOSALS PROCESSED

DOST
PhP 22,227,562.16
96 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 97

Detection Tools
for Helminthic
Neglected
Tropical
Diseases
(NTDs) of Mutual Public Health Importance in the
Philippines and China
Dr. Ian Kendrich C. Fontanilla
University of the Philippines - Diliman

Tropical countries like the Philippines borne helminthiases, in particular to the product export base through
are among those at risk for helminthic taeniasis and anisakiasis. quarantine standard procedures, and
diseases or diseases caused by play a significant monitoring role in
parasitic worms such as hookworms. Through this collaboration, China food safety.
In collaboration with the Tongji is developing diagnostic tools for
University in China, Dr. Ian Kendrich humans and animals, while the As of August 2022, the Philippine
Fontanilla of the University of the Philippines takes charge in developing project team completed animal and
Philippines Diliman (UPD) works to detection assays for environment and environmental sampling in Agusan
develop robust detection tools that food products. The resulting tools del Sur and Cagayan Valley. The
can be used to complement the developed from this collaboration will team collected animal (carabao) stool
monitoring and surveillance system address the need for more accurate samples, water samples, and soil
for priority helminthic neglected and sensitive diagnostics that can samples from actual and potential
tropical diseases (NTDs) in the detect the presence of parasites in snail sites. The project is expected to
Philippines and China. The project different life stages. The established end by May 2023.
focuses on schistosomiasis and food- testing technology will be applied
98 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 99

Paper-Based SinoPhil CHARRME: China-Philippines

Cooperation for Harnessing and
Biomaterials for Diagnostics and
Therapeutics Research and Development

Diagnostic Kit
Accelerating Research and Resources on Center
Microvesicles and Exosomes Dr. Reynaldo DL. Bundalian, Jr.
Dr. Jonel P. Saludes Angeles University Foundation
University of San Agustin

for HIV Drug Extracellular vesicles (EVs) secretion by cells is a natural

mechanism for intercellular communication, which
The DOST and PCHRD work with the Angeles University
Foundation for the establishment of a Biomaterials for

Resistance
includes pathological processes. This process also plays a Diagnostics and Therapeutics Research and Development
role in facilitating disease progression or immune system Center. Funded under the DOST’s Science for Change
modulation. Program (S4CP), the project is part of the Department’s

Detection
thrust in nurturing and encouraging research and
Leveraging the technology for the detection of autoimmune development efforts in the regions.
diseases, this project will develop a probe chip that will
harness the technology of curvature and lipid-sensing. Led by Dr. Reynaldo Bundalian, Jr., the center will focus
The project also aims to create a comprehensive genomic on the development and integration of biomaterials and
Using Recombinase Polymerase Amplification
or proteomic profile of diseases using minimally-invasive nanomaterials for health applications. It also aims to be a
Mr. Angelo D.V. dela Tonga, MSc tools as well as the manufacturing of the diagnostic contributor of point-of-care device (POCT) technologies
National Institutes of Health, microchip tools using Filipino-developed technology for that can be used for the differential diagnosis of priority
University of the Philippines Manila the isolation of extracellular vesicles (EVs). diseases. Furthermore, the R&D center aims to develop
nanomaterials for integration as carriers and solid support
As of November 2022, the project accomplished the for immunogen in vaccine preparations for different
HIV continues to pose significant Institutes of Health - University of determine the device’s specificity, design of mutant peptides, accomplished the EV pull diseases.
health risks to public health. Aside the Philippines Manila leads the characteristics (i.e. limit of detection, down assay, fabricated the microfluidic chip, and secured
from the lack of definitive cure, development of a paper-based flow rate, optimum concentration of samples from SLE patients for the determination of The program is composed of three component projects,
the increasing number of patients diagnostic device that will detect HIV detector molecules), repeatability, lipid composition, and assemble and test the chip for namely:
becoming resistant to available drug resistance mutations. The project stability when kept at 4°C and 37°C, identification of microvesicles and exosomes. Development of a POCT Device for Rotavirus (Viral
antiretroviral drugs is also a challenge team aims to develop a tool that will and use of clinical samples for the Gastroenteritis) Detection
for effective disease management. not require complex infrastructure for assays. Mr. Angelo dela Tonga of the National Institutes of Health - Fecal Lactoferrin, Myeloperoxidase, and Calprotectin as
easier deployment. University of the Philippines Manila leads the development Differential Markers of Pediatric Acute Gastroenteritis: A
To help address this challenge, Mr. The project is now in its third and final of a paper-based diagnostic device that will detect HIV drug Preliminary Investigation
Angelo dela Tonga of the National To date, the team was able to year of implementation. resistance mutations. The project team aims to develop a Synthesis of Biocompatible Nanomaterial Conjugated
tool that will not require complex infrastructure for easier Rabies Peptide Immunogen
deployment. To date, the team was able to determine the
device’s specificity, characteristics (i.e. limit of detection, To date, the project team performed anti-rotavirus antibody
flow rate, optimum concentration of detector molecules), production, recruited participants, and synthesized
repeatability, stability when kept at 4°C and 37°C, and use polymer samples.
of clinical samples for the assays. The project is now in its
third and final year of implementation.
100 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 101

BIOMEDICAL DEVICES
ENGINEERING FOR HEALTH
T he Council recognizes the need for locally-made, affordable, safe, and reliable hospital and biomedical devices
that comply with existing regulatory and industry standards. Through the Biomedical Devices Engineering for
Health Program, the Council aims to:

• develop accessible, affordable, good-quality, and innovative biomedical devices and technologies that consider
sustainability of materials, manufacturing processes, and products;
• develop skills and expertise in biomedical engineering and related areas, and;
• contribute to establishing and strengthening support systems towards a Philippine Biomedical Devices Industry

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 79,543,006.34
11NEWLY-APPROVED
9 COMPLETED
19 COMPLETED
10 NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
40 PROPOSALS PROCESSED

DOST
PhP 126,753,675.80
102 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 103

Cementless Hip
Replacement System Development of a Magnetic Distal Targeting Device
Dr. Ramon B. Gustilo for Intramedullary Nails
Orthopaedics International Inc. Engr. Jude Sasing
Orthopaedic International Inc.

Intramedullary nailing is a process used for treatment of long bone

fractures. This process includes distal locking, which requires the use
of c-arms x-rays. C-arms x-rays, however, are not widely accessible
in Philippine hospitals.

Relative to this, Engr. Jude Sasing of the Orthopaedics International,

Inc. (OII) leads a project that aims to develop a magnetic distal
targeting device for intramedullary nails that will not require an
x-ray. The development of the device will enable Filipino surgeons to
perform intramedullary nailing on patients easily, accurately, and at
an affordable cost.

The project team developed two design options. The first option is
a distal targeting device that can be used with existing nails from
the OII. This uses a tubular permanent magnet and a three-axis
magnetometer. The magnet is attached to the tip of the distal drill
sleeve so that its axis is collinear with the axis of the drill bit or trocar
pin. The second design is a distal targeting device that can be used
for different brands of nails. It uses three-dimensional (3D) magnetic
tracking of position and orientation. The basic components of the
device are an electromagnet assembly composed of two coaxial but
non-coincident electromagnets, and a three-axis magnetometer.

In the Philippines, it is estimated that more Inc. aims to locally manufacture cementless THA
than 170,000 patients need to undergo total hip that will comply with international standards. Aside
arthroplasty (THA) annually. While the procedure from quality and cost, the project team will also
may be done using cement or cementless hip look at various innovations including a modular
systems, studies show that cementless hips extension stem and a cup positioning system that
perform better in younger patients. will allow more orthopedic surgeons to perform the
procedure in different parts of the country.
However, cementless implants are estimated to be
twice as expensive compared to cemented ones. To During the first year of project implementation, the
make this procedure more accessible for Filipinos, research team completed the design and initial risk
Dr. Ramon Gustilo of the Orthopedic International management.
104 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 105

Energized Reusable Laparoscopic Blunt

Dissector
Dr. Deogracias Alberto G. Reyes
Sacred Heart Hospital of Malolos, Inc.

In minimally invasive surgery, the operation consists of

a variety of techniques that cause less damage than
open surgery, giving patients less complications. One
of the first types used is laparoscopy. Laparoscopy is
done with one or more small incisions by using small
tubes, tiny cameras and surgical instruments. This kind
of operation usually requires remarkable time and may
cause muscle pains for the surgeons.

To make this procedure easier for surgeons, the project

aims to design an energized reusable laparoscopic blunt
dissector (ERLBD), which will reduce the operating
time and consumables used during the procedure. The
use of the ERLBD is envisioned to lead to safer, more
affordable, and ergonomic surgeries. POWer: Mobile Biomedical Device Unit to provided with these devices in the following parameters:
Enhance Access to Prosthesis and Orthosis fabrication and maintenance time, adjustment and repair

During the first year of project implementation, the

Devices incidence, and patient satisfaction.
Dr. Josephine Bundoc
team completed the training among personnel who will
Physicians for Peace Philippines Currently, Physicians for Peace Philippines has an
conduct the experiments and activities for the project.
operational mobile workshop for assistive devices through
The design and fabrication is also completed, which
Led by Dr. Josephine Bundoc of the Physicians for Peace the support of various donors. The mobile workshop was
produced targeted 5 mm and 3.5 mm prototypes.
Philippines, the project aims to enhance access to quality developed to enhance access to biomedical prosthesis
Benchtop trials for the energized and non-energized
assistive biomedical devices for persons with mobility and orthosis devices in areas without a facility-based
blunt dissector were performed using the customized
impairments, especially to low-resource LGUs. The workshop.
jig for the prototypes to standardize the placement and
project team utilizes a mobile assistive device workshop
control the amount of force being transmitted by an
to develop prosthesis and orthosis devices that are The team is set to evaluate the quality of the devices
instrument. Statistical consultation recommendation was
comparable with those developed in a facility-based manufactured in the mobile workshop and conduct a
also done by performing 10 trials for each instrument for
workshop and at par with existing standards. The project cost-effectiveness analysis.
the benchtop experiments. The team also performed the
assesses prosthetic/orthotic outcomes among patients
Bland-Atlman test and T- test on data analysis. Safety
protocols were also established after performing animal
trials with the prototype. Thermal damage was accessed
by collecting gallbladder tissue for laboratory analysis.
Patent consultation with lawyers is currently ongoing.
106 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 107

T he Re-emerging and Emerging Diseases (RED) Program of PCHRD envisions to utilize research on the

RE-EMERGING AND
development of local and novel technology platforms, therapeutics, preventive measures, surveillance, control and
management protocols against re-emerging and emerging diseases, for the benefit of the Filipino people, especially
those marginalized and impoverished.

EMERGING DISEASES The RED Program is an expansion of the Dengue and Other Arboviruses (DOA) Program and was created in 2021.
This year, the RED program was able to support studies which fortifies and allows new collaborations with different
institutions both in the private and public sector, serving as a start in addressing the gaps in health research.

Some of its major accomplishments in 2022 are the commencement of Inter-Regional Network through One Health
Approach to Combat AMR program consisting of eight (8) different HEIs from Luzon, Visayas and Mindanao, the
approval of additional three (3) projects under the Virology and Vaccine Institute of the Philippines (VIP) program, and
twelve (12) new HNRDA projects to be implemented for the next few years. These projects include patient support
system, dengue studies, oral vaccine for COVID 19, vector borne studies and antimicrobial resistance. This brings
forth opportunities towards attaining the program’s goal that is to utilize research for the benefit of the Filipino people.
In 2023, the RED program expects to fund projects that address re-emerging and emerging communicable diseases,
antimicrobial resistance (AMR), and preventive interventions against re-emerging and emerging diseases.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 43,434,962.94
12 NEWLY-APPROVED
7 COMPLETED
19 COMPLETED
28NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
32 PROPOSALS PROCESSED

DOST
PhP 452,408,144.57
108 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 109

Seasonal Arboviruses of Aedes albopictus in Highland

and Lowland Sites of Cebu City
Dr. Frances Edillo
University of San Carlos (USC)

Various vector control methods combined with health-control interventions have

helped reduce dengue burden. However, with the effects of climate change, new
prevention and control efforts are needed to counter the potential consequences of
climate change on the geographic range and mosquito-borne arboviral incidence.

This study examined the presence of dengue virus serotypes (DENVs) in Ae.
albopictus or Asian tiger mosquito collected from six highland and lowland sites of
Cebu City, Philippines. Through bi-monthly collection of eggs, larvae, and pupae,
during the dry and wet seasons, DENV detection was done through RT-PCR of
pooled RNAs of adult Ae. albopictus.

In 2022, the study found that DENVs in Ae. albopictus varied between seasons.
DENV-2 and DENV-4 differed seasonally between sites of varying altitudes. Similarly,
during the wet season, the mosquito harbored more DENV-1 in lowland sites and

Dengue-related
DENV-3 in highland sites. Meanwhile, during the dry season, the mosquito played
an important role in DENV maintenance between altitudes. From the results of the
study, the team recommended extending services of dengue vector surveillance in

research in the
the highlands aside from efforts implemented in the lowlands, and installing water
pipelines in the rural highlands to minimize the practice of water storage in artificial
containers that serve as breeding sites of this species.

Philippines
110 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 111

Center for Vector of Diseases of Public and resistant mosquito population, specifically of Aedes
Health Importance in the Philippines for aegypti and Aedes albopictus. Once a good amount of
Region IV (CVDPHIL, Region IV) samples are obtained, the eggs would be reared and
Dr. Divina M. Amalin undergo insecticide resistance bioassays.
De La Salle University (DLSU)
To date, 209 ovitraps were deployed across Laguna,
Along with the rising dengue cases across the country, Rizal, and Cavite. The team explores methods of blood-
the growing resistance of mosquitos against insecticides feeding the hatched mosquitoes, in preparation for the
stresses the need for more efforts towards managing the mass rearing of the mosquitoes.
spread of dengue. The Center for Vector of Diseases of
Public Health Importance in the Philippines for Region The development of the bio-mosquitocidals was also
IV (CVDPHIL, Region IV) is a program implemented by initiated which confirmed the potential of B. asiatica and
the De La Salle University (DLSU) that contributes to Bacillus spp. as sources of mosquitocidal formulations.
this goal. Crude extracts of B. asiatica will be further assayed to
compute important lethal concentration values by Year
The program carries three main goals: 1) establish 2. This will be followed by the identification of specific
the susceptibility of Aedes mosquitoes against bioactive compounds present in the extracts.
mosquitocidal, 2) develop a bio-mosquitocidal using
B. asiatica and Bacillus spp., and 3) develop biological On the other hand, biosurfactants from Bacillus spp.
control strategies for mosquito vectors, Aedes spp. (after confirmation of their biosurfactant production)
using natural organisms. will be extracted, purified, and characterized. Different
assays will be performed in order to assess the effects
Led by Dr. Divina M. Amalin, the team conducted field of these two formulations on the different growth
collections of mosquito eggs using ovitraps across stages of mosquitoes (i.e., as larvicides, pupicides or
Region IV-A which will serve as samples for the adulticides).
establishment of the quality reference for the susceptible
IoT-Based OL Trap and Community Dengue The project team developed an IoT OL trap working
Early Warning System (C-DEWS) for prototype by integrating a smart camera to capture and
Cauayan City, Isabela count the mosquito eggs captured by these traps and has
Dr. Betchie Aguinaldo already started a soft field deployment to gather mosquito
Isabela State University eggs in Isabela. The prototype’s images are processed by
the algorithm designed by the project team to count the
In 2022, the Department of Health (DOH) recorded a mosquito eggs.
182% rise in cases of dengue, hitting over 200,000 cases
from January 1 to December 17, 2022, compared to the In the setups, the project team has successfully installed
over 78,000 cases in 2021 during the same period. antennas in barangays identified for the rollout, to allow
the CDEWS IoTs to transmit the data gathered from these
Contributing to dengue mitigation efforts, Dr. Betchie traps to the database developed that would allow the
Aguinaldo of the Isabela State University undertakes a front-end users to count and compare the dengue cases
research study aiming to enhance the existing ovicidal in Isabela to the egg counts, counted by the IoT OLtrap.
larvicidal traps by digitizing and automating the recording
of dengue larvae, while recording the installed OLtraps Currently, the project team is applying for a utility model
in designated locations in Cauayan City to compute the for both the device and the algorithm. The project team
index in real-time. published a paper, regarding the algorithm they have
developed that would allow the IoT OL trap to count the
captured mosquito eggs.
112 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 113

Vaccine
mix-and-
match
A Study Evaluating the Safety and
Immunogenicity of Mixing Different
COVID-19 Vaccines and Vaccine Platforms in
Filipino Adults

Dr. Michelle Joy B. De Vera

Philippine Society of Allergy, Asthma and Immunology

To mainly address the COVID-19 vaccine supply shortages

in the Philippines, this study aims to demonstrate
the interchanging/mixing administration of available
COVID-19 vaccines in the country, particularly the safety
and immunogenicity of completing the vaccination series
with available COVID-19 vaccines in the Philippines in
those given Sinovac as the first dose.

As of May 2022, the study completed participant

recruitment and vaccination schedules in all five trial
sites. First interim analysis showed that heterologous or
mixed vaccine schedules are non-inferior to homologous
vaccine schedules with no evidence of non-beneficial
effects noted in the analysis.

Aside from this, mixed vaccine schedules resulted in

significantly larger neutralizing antibody responses than
homologous vaccine schedules. The team observed a
trend towards higher proportions of local and systemic
reactions among mixed vaccine schedules compared to
homologous vaccine schedules, however, this trend is not
statistically significant on the most part; and, no serious
adverse events or suspected unexpected serious adverse
reactions attributable to the vaccines were reported.
114 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 115

Predicting jaundice among infants in the first The Philippine COPD Profile and Survival
24 hours of life Study (CPASS)
Dr. Maria Esterlita V. Uy Dr. Tim Trinidad
Philippine Society of Newborn Medicine Philippine College of Physicians

Jaundice is the most common cause of morbidity during Chronic obstructive pulmonary disease (COPD) is a
the neonatal period of infants based on the annual census preventable and treatable disease characterized by airflow
of the PGH. The disease is caused by the concentration limitation that is not fully reversible. It is primarily known to
of bilirubin in the blood, which is a yellow pigment made damage lung tissues in varying severity.
during the breakdown of red blood cells. It is also the most
common cause of readmission of newborn infants. Recognizing the risks of COPD, this five-year project aims
Guitar Lessons for Restoring Hand Function College of Music aims to test the use of classical guitar
Aiming to contribute methods to predict the occurrence to identify the profile and distribution of COPD phenotypes
Among Patients with Unilateral Hand playing as an alternative treatment in the restoration
of jaundice among infants, this project determined the among Filipino patients. The project outputs will provide
Impairment from Chronic Stroke (G.T.A.R.A.) of hand function among patients with unilateral hand
predictive value of an infant’s bilirubin levels within the the necessary information, disease trends, and statistics impairments.
Prof. Nathan Neil Manimtim
24th hour of life (24th HOL) in developing jaundice. aimed to increase the understanding of physicians about
University of the Philippines- College of Music
The study screened infants on the 24th HOL using the the local phenotypic distribution of COPD and its survival Professor Manimtim's team designed a set of guitar
Bilistick system, a point-of-care hand-held device which pattern, which is the key to adequate clinical response exercises that can achieve hand function rehabilitation
The use of research-based music intervention in the field
requires only one drop of blood by heel prick. An infant is in terms of prognostication of the disease and long-term effects similar to exercises currently used in traditional
of medicine is gaining ground in many countries such as
considered to be of high risk for hyperbilirubinemia with a care planning. occupational therapy sessions for patients with one
in the United States. In the Philippines, music therapy is
bilirubin level of greater than or equal to 17 milligrams per impaired hand and one normally functioning hand. As of
not currently an established field but its principles may
decilitre (mg/dL). As of 2022, the project accomplished recruitment of December, two (2) patients completed the experimental
be applied in the practice of physical and occupational
targeted 2,075 participants for the spirometry testing. treatment program and are awaiting post-treatment
therapy to potentially attain its reported benefits, which
Other activities of the project were also done, despite evaluation, while four (4) are currently undergoing the
include improving client participation as well as easing
In 2022, the project established a predictive value of the expected difficulties in patient follow up and data experimental treatment program. Outputs of the project
the discomfort and difficulty associated with the exercises.
the 24 HOL bilirubin in the development of significant collection. may serve as reference and encourage further studies
hyperbilirubinemia at the 72nd HOL. A bilirubin level on research-based music intervention for other medical
Exploring the potential of research-based music
greater than or equal to 7.5 mg/dL at 24 HOL is the Data from the project may be used by policymakers as conditions in the Philippines.
intervention in the Philippine setting, a project by Prof.
optimum cut-off value for predicting hyperbilirubinemia. a guide in the allocation of common respiratory drugs
Nathan Neil Manimtim of the University of the Philippines-
This has an overall diagnostic accuracy of 72.89%, in primary care centers, appropriation of budgetary
sensitivity of 67.96%, and specificity of 73.27%. By the requirements for prevention, or as a basis in case-rate
end of the project, the team aims to develop and adapt packages for the Philippine Health Insurance Corporation.
a bilirubin screening program for different hospitals
nationwide; expand the screening to local health centers
and rural health units; and, develop a bilirubin nomogram
among late preterm infants in the Philippines.
116 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 117

Association of COVID-19 Infection and Disease Outcomes

among Hospitalized Patients in Metro Manila

Prospective
Dr. Terrence Regala
TOP UP Training Center and Research Consultancy Inc.

Urban and Rural

Epidemiologic
(PURE) Study
Dr. Antonio Dans
University of the Philippines-Manila

The World Health Organization to truly define the cardiovascular ongoing follow-up of activities across infection. Cardiovascular outcomes had
(WHO) identifies cardiovascular risk of individuals and populations. all sites. Data collection through higher incidence rates among COVID-19
diseases (CVDs) as the leading cause The final product will go beyond the community and house to house With the increase in t h e patients and increased the odds of
of death worldwide, and responsible geographic limits of the Framingham visits were done to all scheduled prevalence negative disease outcomes significantly.
for a third of deaths in the Philippines. heart study, a study that identified high participants including blood of cardiovascular diseases among
blood pressure and high cholesterol extraction, ECG and spirometry. COVID-19 patient, this DOST-PCHRD By the end of the study, the project team
To generate data on the risk factors as common factors that contribute to supported project aimed to determine the was able to determine that cardiovascular
for CVDs specific to Filipinos, Dr. the risk of acquiring CVDs. The PURE Initial results showed that lower moderating role of cardiovascular outcomes on the outcomes, particular ST-elevation myocardial
Antonio Dans of the University of the Study will include non-traditional income countries are at higher risk association of COVID-19 infection and disease outcomes infarction, CVD disease infarct or cerebrovascular
Philippines-Manila, in collaboration non-biomedical factors such as for CVDs due to limited access among hospitalized Filipino patients. The project was disease, pulmonary embolism and atrial fibrillation
with Population Health Research stress, place of residence, race, socio- to primary prevention, secondary conducted in selected tertiary hospitals in Metro Manila, were significant moderators of the association between
Institute (PHRI), is on the 9th year economic status and more. It has prevention, and lower educational Philippines. COVID-19 infection and poorer disease outcomes. With
implementation of the Prospective also expanded and launched a PURE attainment which affects the health this, the study could serve as a guide for clinicians in
Urban and Rural Epidemiologic COVID sub-study which has started seeking behaviors of the population. In the study, a total of 763 eligible medical records of which they should be vigilant in monitoring, preventing,
(PURE) Study. conducting surveys and collection of The study also pointed out the high hospitalized adult Filipino patients who had RT-PCR and managing these cardiovascular complications among
blood samples for data gathering. intake of refined carbohydrates as a tests from March 2020 - 2022 were reviewed. Data COVID-19 positive patients by using prognosticating tools
With the data from PURE, a factor contributing to the risk of CVD. showed that patients confirmed with COVID-19 infections and scoring systems and by implementing institutional-
cardiovascular risk calculator will be A total of 5,024 participants Data generated by PURE will provide had higher likelihood of developing negative disease based clinical pathways or algorithms to ultimately
developed that is specific for Filipinos, were enrolled in the study. These knowledge and novel discoveries outcomes, particularly those with severe to critical improve patient status
or if appropriate, an international participants will be followed up every on the possible causes of higher
calculator that incorporates traditional 3 years (3Y, 6Y, 9Y) in 3 PURE sites risk for CVDs. It may guide policies
risk factors as well as emerging risk (Urban – Tondo, Rural – Quezon and encourage efforts towards
factors. The PURE study attempts to province, HSES – Cainta, Rizal). preventative measures, especially for
develop the technology necessary Currently, the project team has an high-risk individuals.
118 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 119

Virology and Vaccine Institute of the To date, the VIP Project 7 which focuses on the development
Philippines (VIP) Program of a COVID-19 vaccine from antigenic peptide virus-like
Dr. Annabelle V. Briones particles (VLPs) has completed the selection of antigenic
Industrial Technology Development Institute (ITDI) peptides, the identification of SARS-CoV-2 immunogenic
peptides, characterization of VLP samples by mass
The emergence of SARS-CoV-2, a novel strain of the protein separation, and VLP characterization by electron
Testbeds for Low-Cost Ventilation System
coronavirus, in 2020 highlighted the need for R&D microscopy, and SARS-COV-2 peptides were identified
in Tropical Regions for Risk Reduction of
capacities in virology research. Having a pool of highly- using VLP-serum antibody binding by Direct ELISA from
Infectious Aerosol and Virus Transmission
trained virology experts and appropriate facilities could sera of patients with history of SARS-CoV-2 infection.
Dr. Edward Querikiol
have enabled local researchers to conduct studies on
University of San Carlos - Talamban Campus
the virus as quickly as possible and guided authorities in In Project 8 focusing on the development of COVID-19
implementing evidence-informed response strategies. In antibody test kits using enzyme immunoassay, the project
The COVID-19 pandemic emphasized the importance
response to this, the DOST initiated the establishment of team is already validating the developed ELISA kit for the
of proper ventilation in preventing the spread of aerosol
the Virology and Vaccine Institute of the Philippines (VIP). detection of COVID-19 antibodies.
and virus transmission. In response to this need, the
The VIP is envisioned to be the country’s premiere research
University of San Carlos, Cebu, in close collaboration
and development institution that will undertake studies on The target beneficiaries of the VIP program are public
with Max Planck Institute of Chemistry (MPIC) in Mainz,
novel, emerging and re-emerging viruses affecting not health professionals, policy planners, and the community
Germany, is implementing a project that aims to develop
only humans but animals and plants as well. which can use results of the studies in general, in better
and demonstrate the effectiveness of a low-cost ventilator
understanding viruses of clinical, agricultural, industrial,
system for tropical indoor environments to curb the further
DOST has initiated several R&D projects through the and environmental importance. In particular, the following
spread of airborne viruses.
Industrial Technology Development Institute (ITDI) as the projects are being implemented in partnership with several
program lead of the VIP, and the DOST-PCHRD being the local and international researchers and institutions.
The team developed a working prototype of the ventilation
studies’ monitoring agency.
system which will aid in the transition to the new normal
and will be beneficial for indoor environments, such as
classrooms, business offices, public transport vehicles,
and small manufacturing facilities, among others.

In 2022, the ventilation system was also tested for its

effectiveness with real students during face to face
classes, and was assessed if the ventilation system will
not cause any degree of discomfort among its users. The
current prototype utilizes readily-available materials such
as PET bottles, cable ties, duct tape, and glue to enable
easy deployment. Approximately, one unit of the prototype
ventilation system is projected to cost Php 5,000, of
which the cost is expected to significantly go down after
negotiation with suppliers and manufacturing partners.
120 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 121

T he Digital Health and Frontier Technologies (DFTH) aims to address the need for an efficient, equitable, and

DIGITAL AND FRONTIER

affordable healthcare system and patient management through evidenced-based policy making and innovative
healthcare interventions via research and development of tools utilizing artificial intelligence and new fields of
information and communication technologies in digital health.

TECHNOLOGIES FOR In 2022, the program monitored the completion of four (4) projects: 1) Rapid Assessment of Health Information
Systems towards Pandemic Resiliency and UHC in Two Provinces ended on March 31, 2022, and 2) RabCast: Proof-

HEALTH
of-concept for a Forecasting Tool for Rabies Spread in Davao City Through Combined Genomic and Mathematical
Approaches ended last August 31, 2022, and 3) Immersive Technology for Health Research Programs. Meanwhile, 26
DFTH proposals were received during the Call for Proposals.

In the next year, the program is expected to process proposals including the following: 1) Artificial intelligence in
developing screening and diagnostic software, for enhanced efficiency of healthcare service delivery, and for
information dissemination; and 2) Big data analytics (or health data analytics) to influence evidence-based decision-
making, or policy translation for targeted health intervention, with targeted registries as an output, and for information
dissemination purposes.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

PCHRD
PhP 32,393,804.14
9 NEWLY-APPROVED

4 COMPLETED
19 COMPLETED
9 NEWLY-IMPLEMENTED
7 NEWLY-IMPLEMENTED
26 PROPOSALS PROCESSED

DOST
PhP 4,958,256.00
122 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 123

RabCast:
Forecasting
Rabies Spread in
Davao City Dr. May Anne E. Mata
University of the Philippines Mindanao

Through combined genomic and transmission in Davao City and that a journal while six more journals are
mathematical approaches, the should not be ignored given that expected to be published within the
RabCast project established a cats were the second most populous first quarter of 2023. Moreover, four
predictive tool in the form of an online domestic animal in the city. members of the team presented
dashboard to assess the spatial the papers at the 53rd Asia-Pacific
spread of rabies in Davao City. Novel Assessments further showed the Academic Consortium for Public
data from this study identified that limiting effect of COVID-19 on Health Conference 2022, held at the
the Talomo and Tugbok districts are rabies spread during the pandemic. Marriott Hotel Manila in Pasay City,
significant hotspots of canine rabies The development of the RabCast Philippines, on September 22–23,
in the city. dashboard in the next phases of 2022. The study entitled “Optimal
the program will provide a powerful Control Theory Applied to a Rabies
Distribution maps also showed that strategy for rabies control as it Epidemiological Model with Time-
interventions are randomly distributed will allow the local government to Dependent Vaccination in Davao
across the districts as predicted. strategize a proactive rabies control City, Philippines” won first place
Mapping of new viruses with previously program by identifying high-risk areas for virtual abstract presentation
sequenced baseline samples revealed in advance and targeting them for while the study entitled “Effect of
the emergence of new-sub lineages intensive campaigns. COVID-19, Vaccination Ratio, and
possibly diverged from undetected, Human Population on the Reported
unidentified, older variants; and The project accommodated three Canine Rabies Cases in Davao City,
spread analysis presented significant undergraduate students who worked Philippines: A Panel Regression
transmission routes between Davao on their thesis, one undergraduate Analysis” won second place for an
City and its neighboring provinces in student was hired as an intern, and on-site poster presentation. Additional
Davao City, Philippines. In addition, twelve City Veterinarian’s Office two papers on genomic analysis were
both epidemiological and simulation (CVO) collaborators trained under the also presented in poster and podium
models showed that despite small, supervision of the RabCast project. on-site presentations.
there still exists a significant impact
from cats on the dynamics of rabies On October 2022, the study published
124 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 125

LGU-mandated eHealth Networked Services Orthogeriatrics and the Fracture Liaison

for Universal Health Care (UHC LeHNS) Service for Elderly Hip Fractures
Dr. Dennis Batangan Dr. Irewin A. Tabu
Ateneo de Manila University- Institute of Philippine Culture University of the Philippines- Philippine General Hospital

The passage of the Universal Health Care (UHC) Law The project aimed 1) to describe the clinical, treatment,
reiterated the relevance of leveraging eHealth solutions and post-treatment characteristics of geriatric patients
to improve healthcare delivery for Filipinos. In response with fragility hip fractures, and 2) to measure the following
to this, this project will assist local government units in outcomes in geriatric patients with fragility hip fracture,
implementing Digital Health Interventions (DHIs) by 3) to determine significant clinical, treatment and post-
developing local health information systems (LHIS). treatment factors, to be known as key performance
indicators, associated with the outcomes to be studied, 4)
Specifically, it aims to co-design and co-develop LHIS to generate an electronic data collection framework that
models that support the digital health and functional includes key performance indicators for use in a future
requirements of national health information systems. The sustainable national hip registry.
initiative will utilize eHATID System Techno-governance
projects which are eHealth technologies developed by Dr. In 2022, initial orientation on the combined model of care
Batangan and his team. orthogeriatric fragility fracture management (OFFM) and
the fracture liaison service (FLS), which are approaches for
In 2022, the project team has kept in constant secondary fracture prevention, were conducted through
communication with local government units in Pangasinan focus group discussions, together with periodic follow-
Rapid Assessment of Health Information The process of tool development was divided into 3 and Cagayan de Oro City to ensure smooth integration ups by the research coordination team. The research
Systems towards Pandemic Resiliency and phases: item development, scale development, and and realization of the roll-out of their interoperable system. coordination team also provides direct supervision in
UHC in Two Provinces scale evaluation. The domains identified included (1) HIS In Pangasinan, the eLearning Program was re-offered to both implementation of the treatment pathways and data
Dr. Miguel Manuel C. Dorotan capacity, and (2) HIS Functions. Under the HIS Capacity revamp its content structure, conduct and management, collection. In addition, quality management of data input is
Alliance for Improving Health Outcomes (AIHO) domain, the items to be assessed included: governance, and communication strategies based on the results also done by the team every four (4) months.
policy, financing, ICT assets, and Human Resources. and recommendations of its evaluation process. More
To assess the Health Information System in the Provinces HIS functions, meanwhile, looked into data generation, consultative meetings with the technical working group of For patient recruitment, there are already 214 patients
of Aklan and Leyte, a comprehensive Health Information data compilation, data analysis, and communication and Pangasinan Health Office were also conducted to address with baseline data, and ongoing 109 patients are being
System (HIS-RAT) was developed. In 2022, the resulting use of information/knowledge generated from the data issues and bugs encountered in the basic version of the followed-up. This is expected to rise in number later once
tool was pilot-tested prior to the implementation in Aklan gathered. Units of measure and scales for measurement Smarter Integrated Local Health Information System the partner institutions recruited to implement the study
and Leyte, who were the main partners and beneficiaries were developed and given to subject matter experts for (SMILHIS). have formed their own multidisciplinary orthogeriatric
of the study. evaluation for validity. team, and especially their own dedicated data entry
In their implementation site in Cagayan de Oro City person. Meanwhile, collaborating physicians with patients
(CDOC) also known as SMILHIS CDOC, the team treating geriatric patients using the combined pathway of
conducted an on-site Design Thinking Workshop aimed care have input entries in the digital database, REDCap
to review the objectives of the project and assess the database, from hard copies of the information data sheets.
status of the customization of the interoperable layer and The REDCap database is a secure web application for
several aspects, specifically, governance, sustainability, building and managing online surveys and databases.
and capacity-building. The team is also pursuing partnerships with twenty-one
(21) institutions to collaborate with the study.
126 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 127

LISA
Robot
Logistic Indoor Service Assistant
Telepresence Robot
Dr. Anthony James C. Bautista
Department of Mechanical Engineering, University of
Santo Tomas

Mobile service robots are designed to perform tasks or services application and evaluate its navigation performance involving addition, the issue regarding WiFi connection was also resolved The LISA Robot was presented at an international
useful to the well-being of humans. With the busy and stressful static and dynamic obstacles. The team will also study the to result in a faster response time for the robot, leading to faster conference entitled, “International Conference on Humanoid,
work environments experienced by health professionals, health adaptability of the LISA robot in private isolation rooms of mapping capability. This improvement also enabled the robot Nanotechnology, Information Technology, Communication
facilities are a potential application of these mobile service hospitals based on the Overall Equipment Effectiveness to be integrated into a hospital’s existing WiFi network system and Control Environment, and Management (HNICEM)” and
robots. (OEE) classifications namely; flexibility, mobility, modularity, as long as the PC is also within the coverage area of the WiFI exhibited during the 2022 National Science and Technology
compatibility, and economy. Lastly, the team is set to conduct network. Week which drew a large crowd of students. Finally, in part
Exploring this potential, a Logistic Indoor Service Assistant or policy-gap analysis in using telepresence roots in private of their 6Ps and 2Is, the project team presented the purpose
LISA telepresence robot is being developed by Dr. Anthony isolation rooms of hospitals. Meanwhile, on the hardware end, a change in wheel positioning and functionalities of the LISA Robot to students invited from
James C. Bautista to enable healthcare workers to perform was implemented in order to navigate irregularities on the floor Iloilo Science and Technology University highlighting the role
mundane tasks such as delivering documents, samples, or For 2022, progress on the development of the LISA Robot has such as humps, floor cavities, and cables. The project team of LISA Robot in aiding healthcare workers to provide quality
medicines within healthcare facilities remotely. also been steady. An improvement that was implemented was also consulted with the Industrial Engineering Department of healthcare.
the use of the Real Time Clock (RTC) model in the LISA Robot UST to conduct a time and motion study to determine the most
Specifically, the team aims to develop an Android Application for local time keeping in order to avoid time lags between the efficient schedule of the LISA Robot operation in the context of
that will allow WIFI control for the LISA robot for telepresence robot and the host controlling the movement of the robot. In the existing practices and activities in a hospital environment.
128 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 129

Immersive Technology Applications in Health

Rehabilitation Management of Patients with Rehabilitation Management of Patients with
Behavioral and Psychological Symptoms of Cerebral Palsy and Mobility Limitations
Dementia (BPSD) Dr. Jaime Caro
Dr. Jaime Caro University of the Philippines Manila
University of the Philippines Manila

One of the undertakings that leverage advancement of Aside from patients with dementia, Dr. Caro’s team is also
technology in health is the use of immersive technology as developing an immersive technology system specifically for
an alternative rehabilitation measure of patients. Intended for pediatric patients with cerebral palsy and mobility limitations,
Dr. Jaime Caro those with symptoms of dementia, this study will develop an the most common cause of motor disability worldwide. It also
University of the Philippines Manila immersive technology system for rehabilitation in collaboration aims to create an immersive gamification technology system
with uCreate Laboratory, University of Edinburgh, United for the management of the conditions of the patients and to
Kingdom, led by Dr. Veeda Michelle Anlacan. determine its acceptability, usability, and safety, as traditional
therapy treatments involving surgical procedures and use of
The project utilized virtual reality projected through both a medications, or both are rigorous and repetitive.
head-mounted device and a semi-Cave Automatic Virtual
Environment (semi-CAVE) set-up to provide an alternative In 2022, the project team was able to develop a prototype for
rehabilitation approach for dementia patients through the head-mounted device and semi-Cave Automatic Virtual
innovative interventions for the management of behavioral Environment (semi-CAVE) set-up with three (3) games, and
and psychological symptoms of dementia. completed the alpha and beta testing. Further, attendance
to virtual conferences on the use of virtual reality tools was
In 2022, the team tested the software with medical practitioners also attended, including poster presentations. Building on
for their initial clinical studies. Focus group discussions to the outputs developed from the phase 1, phase 2 trials with
improve on the prototypes were also conducted. Some of the pediatric patients are now ongoing.
improvements done was the incorporation of hand-tracking,
instead of controllers, to interact with the virtual environment,
the integration of a therapist in the device module to provide
spontaneous instructions and guidance to the user, and the
addition of an avatar customization feature. Following these
refinements, initial clinical studies on healthy patients were
done, and the next phase of clinical studies are ongoing.
130 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 131

POWer App:
Mobile Health Application Development for
Remote Screening & Early Detection of Children
with Mobility Impairment
Dr. Josephine R. Bundoc
Physicians for Peace – Philippines (PPP)

Early detection is critical in minimizing the negative system errors identified during the testing. In the beta-
impacts of potentially debilitating mobility impairments. testing conducted, bugs were found and resolved in
This project aims to provide identification and screening the form where patients input their data via the mobile
for children with mobility impairment. application. In addition, patient data flow and levels of data
access were also identified.
In 2022, a training module for the application and an
operational and implementation plan for the community- Constructive feedback was provided by both patients and
based assessment was created in collaboration with the their respective guardians, and by rehabilitation specialists.
local government unit to ensure the efficient use of the A second phase of the project is anticipated to implement
technology among its users. As the project is nearing its the mobile application at a larger scale once analysis for
completion, the mobile application developed has been both alpha and beta testing are finished.
undergoing multiple testing and revisions to address
132 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 133

ARCHER
Addressing and Responding to COVID-19
I n 2020, PCHRD created the program entitled, “Addressing and Responding to COVID-19 through Health Research
(ARCHER)” to augment the Council’s financial resources to support COVID-19 research projects that will contribute
to pandemic response.As the COVID-19 virus spreads worldwide, the Philippine healthcare system has been greatly
challenged considering COVID-19’s significant threat and impact in the country. The World Health Organization
(WHO) emphasized the need to accelerate innovative research to help contain the spread of the virus and facilitate
care for those affected.
through Health Research
In the Philippines, health research activities are coordinated by PCHRD. Through ARCHER, The Council has been
leading the efforts in the conduct and support of health research to come up with solutions that can contribute to
addressing the pandemic.

STATUS OF PROJECTS RESEARCH EXPENDITURES IN 2022

15 COMPLETED

2 ONGOING

PhP 85,309,556.12 (DOST)

134 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 135

Assessment of the Gut Microbiome for was no correlation observed between differentially
COVID-19 Diagnosis and Prognosis abundant bacterial biomarkers and laboratory markers for
Dr. Leslie Michelle M. Dalmacio inflammation in COVID-19. The clinical utility of these two
University of the Philippines - Manila markers are of promising significance.

In support of the ongoing efforts to boost the country’s The study can aid in formulating guidelines that will result
COVID-19 testing capacity, the study aims to determine in better outcomes for COVID-19 patients. Demonstration
the utility of the gut microbiome profile in the diagnosis of viral particles in fecal material may elucidate on another
and prognosis of COVID-19. modality of transmission (i.e. fecal-oral) and association of
disease severity with identified gut microbiota may further
As of April 2022, the project has already completed all elucidate on the pathophysiology of COVID-19 infection.
the project’s deliverables. Results of the study suggest
that stool samples can be used to diagnose COVID-19 The project has an overall budget of Php 4,882,812.80
using the local RT-qPCR kit, from day 1 up to 2 weeks (of which Php 2,000,000.00 is charged to the ARCHER
of illness. It also noted a clustering of gut microbial Program fund and Php 2,882,812.80 is charged to the
composition among patients with moderate and severe PCHRD-GIA program fund).
COVID-19. Furthermore, according to this study, there

Development of a Liquid Medium for On- The project recruited patients and collected specimens
Site Inactivation of SARS-CoV-2 for RT-PCR on the following sites: Las Piñas City, Malabon City,
Testing Mandaluyong City, Muntinlupa City, San Juan City, San
Mr. Alexander Sadiasa Pedro City, and the RITM. The production of inactivation
Research Institute for Tropical Medicine will cut the cost of using Viral Transport Medium (VTM) and
will also save the time and cost of inactivating specimens
Contributing to the current practices of handling swab after collection and transport. This will also ensure the
specimens, a study spearheaded by Mr. Alexander safety of healthcare and laboratory workers from exposure
Sadiasa, MSc, of the Research Institute for Tropical to infectious microbial agents during specimen collection,
Medicine (RITM) aimed to develop a temperature-stable transport, and processing for laboratory-based virus
transport medium that can inactivate respiratory RNA detection.
viruses on-site for real-time PCR testing. It will also the
applicability of the developed transport medium to clinical
specimens for SARS-CoV-2 real-time PCR testing.
“
136 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 137

Testing of saliva
samples recorded a
sensitivity of 79.94%
and specificity of
98.94%. With these
observations, the use
of saliva specimens
for PCR detection of
SARS-CoV2 may have
significant impact in
our response to the
pandemic.
The project aims to determine the suitability of saliva

Suitability of
as an alternative clinical specimen for the detection
of SARS-CoV-2.Completed last December 31, 2021,
a total of 1,661 patients were enrolled in the study

Saliva as an
from whom the following specimens were collected:
nasopharyngeal swab, oropharyngeal swab and
saliva. The patients were recruited from Las Piñas

Alternative
City, Malabon City, Mandaluyong City, Muntinlupa
City, San Juan City, San Pedro City, RITM.

Clinical
The PCR testing of saliva samples recorded a
sensitivity of 79.94% and specificity of 98.94% with

Specimen for
overall percent agreement of 95.06%. With these
observations, the use of saliva specimens for PCR
detection of SARS-CoV2 may have significant impact

the Detection of
in our response to the pandemic. The use of saliva
specimens would reduce the risk of viral exposure
to healthcare workers while minimizing the use of

SARS-CoV-2
personal protective equipment and other medical
resources. Ultimately, this would make high volume
testing feasible if enhanced surveillance is to be
implemented.
Mr. Alexander Sadiasa, MSc
Research Institute for Tropical Medicine
138 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 139

Detecting Cytokine Storm Syndromes and Association of Abnormal Coagulation

Predicting Disease Progression and In- Parameters with Adverse Clinical Outcomes
Immune Cell Phenotype Characterization of Durability and Extent of Protection of SARS- Hospital Mortality Among COVID-19 patients among COVID-19 Patients
Moderate to Severe COVID-2019 Patients at Cov-2 Antibodies Among Patients with
Felix Eduardo R. Punzalan Dr. Geraldine T. Zamora
the Philippine General Hospital COVID-19
University of the Philippines Manila University of the Philippines - Philippine General Hospital
Dr. B. Januario Antonio D. Veloso, Jr. Dr. Ma. Liza Antoinette M. Gonzales
University of the Philippines Manila University of the Philippines Manila
Looking into biomarkers of cytokine storm among As a contribution to existing evidence on managing
COVID-19 patients may help in the development of COVID-19, the study evaluated the association between
Science-based guidelines are necessary for In efforts to understand immunity against COVID-19
guidelines for the management and outcome monitoring blood clots (thrombophilias) and adverse clinical
better management of COVID-19. By providing reinfection, this project aims to describe the durability
of the patients. Parallel to this, the project aims to determine outcomes among patients with moderate to severe
immunophenotyping data specifically for Filipino patients of SARS-CoV-2 antibodies after an initial exposure and
the biomarkers and cytokines associated with disease COVID-19 among patients admitted at the UP-PGH.
to local and international medical specialty societies, the disease, and the extent of protection it confers against
progression and in-hospital mortality among patients with
country can better strategize and improve its policies and reinfection.
confirmed moderate to severe COVID-19 infection. The The proponents concluded that coagulation abnormalities
healthcare practices in dealing with the pandemic.
study covered patients confined in the UP-PGH. were common in patients with predominantly severe
In 2022, the project made significant progress in
COVID-19. There was significant association between
The study aims to characterize the immune cell phenotype monitoring study participants and determining their level
The team completed the project deliverables last March several of these thrombophilias (abnormal platelet count,
among moderate to severe COVID-19 Filipino patients of SARS-CoV-2 antibodies. The proponents are currently
2022. Results of the study suggest that among patients elevated D-dimer level, prolonged INR or PTT, positive ACL
seen at the Philippine General Hospital. conducting statistical analyses and finalizing interpretation
with moderate to severe COVID-19 recruited by the IgM) and adverse clinical outcomes. This suggests the
of results.
study, an elevated D-dimer and lymphopenia within 10 utility of these coagulation parameters in the monitoring
As of August 2022, the project already completed the
days of illness were associated with disease progression of patients with severe COVID-19. Last November 2021,
majority of its deliverables, specifically patient recruitment, The results of the study will be useful to clinicians,
and mortality was observed. An elevated LDH and the study was able to achieve the target sample size and
baseline demographic and clinical data collection, quality researchers, public health practitioners, and policymakers.
hypoalbuminemia within 10 days of illness were also described the coagulation profile of patients with moderate
monitoring of dataset in the REDCap database, sample Information on the durability of SARS-CoV-2 antibodies,
associated with disease progression. Elevated levels of to severe COVID-19 hospitalized at the UP-PGH.
blood collection, and PBMC isolation and cryopreservation. and clues to the whether or not these antibodies are
IP-10 and IL-6 were associated with disease progression
protective against future reinfection, can be used to guide
and mortality. Elevated levels of IL-18 were also associated Results of the study will enable a broad range of clinical/
Expected to end in April 2023, the target beneficiaries of the deployment of limited vaccine stocks, and inform
with mortality. translational and epidemiological studies that would form
this study are physicians and their COVID-19 patients, strategies for returning to the workplace and relaxing
a comprehensive framework for diagnosis, treatment, and
medical community, including local and international social distancing measures.
These results will help develop a pathway/ algorithm to prevention of COVID-19. More importantly, this would also
medical subspecialty societies, COVID-19 researchers and
guide management and outcome monitoring of patients. support the country’s local capacity in addressing the
research institutions, academic/scientific community, and
Patients with COVID-19 could then be screened for continuous threat of emerging and re-emerging infectious
MD-PhD in Molecular Medicine students and graduates.
hyperinflammation which can identify a subgroup of diseases.
high-risk patients for whom immunosuppression could
improve outcomes.
140 PCHRD ANNUAL REPORT 2022 PA R T 1 : R E S E A R C H A N D D E V E L O P M E N T 141

Seroprevalence of SARS CoV-2 in Communities in Health - UP Manila, in collaboration with the Lung Center of the
the Philippines Philippines. It generally aimed to determine the effectiveness of
Dr. Kristine Alvarado-Dela Cruz plasma transfusion on the secondary prevention of death, shock
Research Institute for Tropical Medicine – Department of Health and organ damage from COVID-19.

As the recommended testing procedure for the diagnosis of The project has recruited a total of 119 participants in the study,
COVID-19, PCR has the disadvantage of requiring the presence aged 18-50 years old who are highly suspected or confirmed to
of genetic material from SARS CoV-2 at the time of sample have mild COVID-19. Currently, the project team is preparing the
collection. In this regard, it is key that serologic studies be done terminal reports. The project was started in order to determine the
to provide insight into exposure history and the development of effectiveness of plasma transfusion on the secondary prevention
antibodies in individuals of a given community, also significantly of death, shock and organ damage in COVID-19. It aims to provide
broadening the window period for the detection of past infection data to support the efficacy and use of plasma components as
or exposure. a therapy for sepsis, and in particular for COVID-19. If effective,
secondary prevention offers the promise of shortened hospital
This longitudinal study will estimate the seroprevalence of SARS stay, lesser mortality and lessened need for costly interventions, as
CoV 2 infection in the general population, thereby improving the well as disabilities related to exposure to the organ complications
understanding of COVID-19 transmission, and provide insight and invasive procedures.
into epidemic spread of the disease. This study seeks to estimate
what proportion of the Philippine population have been affected Intravenous Tocilizumab as Treatment for
by COVID 19, as well as the magnitude and timing of antibody Hospitalized Patients with COVID-19
response. Dr. Eric Jason B. Amante
Philippine General Hospital
Completed in July 2022, the study covered four representative
communities namely: National Capital Region (NCR), Luzon, Contributing to the efforts towards discovering treatment
Visayas, and Mindanao. In the same year, the project completed methods for COVID-19, a project led by Dr. Eric Jason B. Amante
the enrollment of study participants, as well as the testing of was conducted to determine the effectiveness of IV Tocilizumab in
specimens for quantitative S-based and qualitative N-based the treatment of severe and critical COVID-19-related pneumonia
antibodies via ECLIA. There were 750 samples selected and patients.
endorsed to the RITM Department of Virology for testing of viral
neutralizing activity via cPass. Implemented by the Philippine General Hospital (PGH), Forty-
nine (49) patients were randomized in the tocilizumab arm and
The results of the study will provide essential data on the 49 in the placebo arm. There was no significant difference in age,
estimated disease burden of COVID-19 in the general population comorbidities, COVID-19 severity, need for mechanical ventilation,
using serologic tests. The data on neutralizing activities of the presence of acute respiratory distress syndrome, or biomarker
antibodies detected will also help disease programs and policy levels between groups. Use of adjunctive therapy was similar
makers to have a better understanding of the pandemic spread, between groups, with corticosteroid used in 91.8% in Tocilizumab
and the presence or absence of protective immunity to the group and 81.6% in the placebo group, while remdesivir was used
disease in the community setting, so as to accurately formulate in 98% of participants in both groups.
strategies for disease surveillance and public health response.
Dr. Amante’s team found that there was no significant difference
between groups on intention-to-treat analysis and difference in
Evaluation of Plasma Therapy for Retarding time to improvement of at least two categories relative to baseline
Progression and Preventing Complications in on the 7-point ordinal scale of clinical status.
COVID-19
Dr. Jose Nevado, Jr. In conclusion, the use of tocilizumab on top of standard of care
National Institutes of Health, University of the Philippines Manila in the management of patients with severe to critical COVID-19
did not result in significant improvement as defined by the World
In response to the need for scientific treatment methods versus Health Organization’s (WHO) 7-point Ordinal Scale of patient
COVID-19, several studies were initiated exploring various status, nor in significant improvement in incidence of mechanical
approaches to address the symptoms of the disease. One of ventilation, incidence of ICU admission, length of ICU stay and
these focuses on the use of plasma therapy. The project was mortality rate.
spearheaded by Dr. Jose Nevado Jr., of the National Institutes of
142 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 143

PART

2
To ensure equity in research
capacity, the Council supports
institutional development initiatives. INSTITUTION
DEVELOPMENT
144 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 145

SCHOLARSHIP GRANTS

The DOST-PCHRD implements scholarship programs as a major strategy to develop

and nurture the country’s critical mass of health researchers. This is vital to the
continued creation of knowledge and technologies for health development.

Scholarship grants are intended for qualified and deserving students who must enroll
in DOST-PCHRD priority graduate degree programs (MS, PhD, and MD-PhD) in local
and international partner institutions.

SCHOLARS
IN 2022 6
GRADUATED

181 ONGOING
16
NEWLY-ACCEPTED
Scholars funded and monitored by DOST-PCHRD in 2022

Status PCHRD-Funded DOST-SEI Funded

(PCHRD-monitored)
COMPLETED
MS 1 -
MD-PhD - 5

Nurturing the next

ONGOING
MS 18 68
PhD 4 20
MD-PhD 44 27

generation of Filipino NEW

MS
PhD
2
6
-
-

health researchers.
MD-PhD 8 -
TOTAL 83 120
 146 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 147

The Council is currently

implementing six
scholarship programs.

LOCAL FOREIGN

MD-PhD in PhD in Health MS Molecular MSc in Tropical PhD Program Cohort Doctoral
Molecular Research Medicine Medicine in Molecular Studies Program
Medicine Biomedicine of The DOST-PCHRD and James Cook
UNITS University (JCU) offer a Cohort Doctoral
Studies Program that will allow
A joint initiative with University of the Operationalized under the University A two-year program which was A two-year program of the DOST- The DOST-PCHRD, the University of professionals to continue addressing
Philippines Manila, is an eight-year dual of Sto. Tomas Graduate School, in implemented through the joint efforts of PCHRD in partnership with the Faculty Trieste (UNITS) and Fondazione Italiana health system needs and saving lives in
degree program that aims to develop and collaboration with the University of DOST-PCHRD and St. Luke’s Medical of Tropical Medicine (FTM), Mahidol Fegato (FIF) entered into an Agreement the Philippines while pursuing a doctoral
train aspiring physician-scientists with South Australia (UniSA), it is a three-year Center College of Medicine William H. University and Southeast Asian in 2019 to develop and implement degree in JCU, a world-class teaching
extensive knowledge and experience program which uses blended learning Quasha Memorial. The program aims Ministers of Education Tropical Medicine a program focused on molecular and research institution. The flexible
in the field of clinical and biomedical and provides an alternative track to to strengthen and upgrade the skills of and Public Health Network (SEAMEO hepatology within the PhD Program in part-time program allows clinicians to
research. acquiring a doctorate degree. This health professionals and researchers in TROPMED Network) Thailand which Molecular Biomedicine of UNITS. The benefit from the expertise of a JCU-
program aims to improve the teaching the field of applied biomedical research. aims to develop and implement foreign three-year graduate program integrates based supervisor while conducting
In 2022, five MD-PhD Molecular and research capabilities of health graduate scholarship programs in basic research and clinics focusing on research locally.
Medicine scholars graduated and professionals. In August 2022, one scholar, tropical medicine with the mission of the study of molecular approaches to
earned their dual degrees. To date, successfully earned her degree. addressing health systems needs in the cancer biology, genetics, jaundice, and In 2022, the first call for applications
the MD-PhD program has a total of 26 In 2022, a total of four new scholars country metabolic diseases. to the new program was posted
graduates. Eight new scholars were were supported under the PhD in last October. Out of the interested
supported this year. Health Research program. Three In 2022, two scholars were supported In 2022, two new scholars were applicants, one was endorsed to JCU
scholars started in the Second in the first implementation of the accepted in the PhD program. last November for further evaluation.
Semester 2021-2022 while one scholar program. The first batch of scholars Meanwhile, there are four ongoing Dr. Marc Edsel Ayes, Laboratory
started during the First Semester started their program in Mahidol PhD scholars who are currently Manager and Clinical Health Officer
2022-2023. University in August 2022. working on their dissertations in Italy. of University of the Philippines -
Philippine Genome Center, was
accepted and will start his doctoral
program early 2023.
 148 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 149

MD-PhD in Molecular Medicine Scholarship

Program Events

MD-PhD Graduates

The MD-PhD in Molecular Medicine is monitored by

DOST-PCHRD under the DOST - Science Education
Institute (SEI) Accelerated Science and Technology
Human Resource Development Program (ASTHRDP).
This year, five MD-PhD scholars completed the program
and attended the UPCM 113th Commencement Exercise
at the University Theater, University of the Philippines
Diliman, Quezon City on 7 August 2022.

Two graduates of MD-PhD in Molecular Medicine

program, Dr. Ourlad Alzeus G. Tangtengco and Dr. Mary
Nadine Alessandra R. Uy, passed the 2022 Physician
Licensure Examination.

MD-PhD Colloquium Summer Immersion Program New Batch of Aspiring Physician-Scientists

(Class 2030)
Included in the line up of activities for the DOST-PCHRD 40th To familiarize the scholars with the R&D landscape of the
anniversary, the UPCM together with the Council conducted country, PCHRD conducted the 2022 Summer Immersion DOST-PCHRD welcomed the new batch of MD-PhD
the MD-PhD Colloquium on 5-6 May 2022 via the event Program for the MD-PhD in Molecular Medicine Batch 12 scholars (Batch 13). The Memorandum of Agreement
online platform and Facebook live. scholars on 13-1 June, 2022 via Zoom Conference. Signing Ceremony was held on 31 August 2022 at the UP
Manila Dormitory. Eight (8) scholars were accepted into
The colloquium provides a platform to update the public on The program aims to orient and expose the future physician- the program for AY 2022-2023.
the latest achievements of the program as well as to inform scientists in the different science and research-oriented
the attendees about latest developments, research, and institutions as a way to foster their research appreciation
innovations regarding health research and development. In and future involvement in S&T and R&D initiatives of the
the event, the scholars were able to share their works on Council. The scholars had the opportunity to virtually visit
schistosomiasis, malaria, COVID-19, Gitelman syndrome, the following DOST agencies and institutions: DOST Central
Kawasaki disease, and HIV which are all pressing health Office, PCHRD, Industrial Technology Development Institute MD-PhD Summit 2022
issues of the Philippines. (ITDI), Food and Nutrition Research Institute (FNRI), UPLB -
Biotech, International Rice Research Institute (IRRI), United To welcome the new batch of MD-PhD scholars, the MD-
Laboratories, Inc. - Sekaya R&D Plant, Philippine Genome PhD Committee conducted the MD-PhD Summit 2022
Center (PGC), Newborn Screening Center - NIH Manila and with the theme: “Dagitab: Damhin ang Kislap ng Haraya”
Research Institute for Tropical Medicine (RITM). on 4 October 2022 via hybrid set-up. The event aims to
immerse the new scholars in the life of MD-PhD (student
and professional) as well as to recognize the achievements
of ongoing scholars during the past academic year.
150 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 151

FELLOWSHIP Fellowship in Epidemiology

Program Development and Pilot Implementation

The Fellowship in Epidemiology Training Program has In 2022, an oral presentation was conducted and was
been identified as a crucial step to capacitate health followed by a series of research fora.
researchers with the required knowledge and skill to be
able to competently carry out quantitative health research. To evaluate the research paper of the fellows, an oral
It is one of the means to build a critical mass of researchers presentation followed by a series of research fora were
with such competencies. conducted on the following dates: 27-28 June 2022, 22
September 2022, 29 October 2022, and 5 November 2022.
In cooperation with the PNHRS Capacity Building Aside from these activities, a modular training activity
Committee, the DOST-PCHRD partners with the University was also organized so that fellows can demonstrate their
of the Philippines College of Public Health Inc. (UPCPHFI) proficiency in quantitative research in public health.
to initiate the implementation of an Epidemiology
Fellowship Program. The project aims to develop and On 7 November 2022, a virtual recognition ceremony was
pilot test a ten-month Epidemiology Fellowship Program conducted for six (6) fellows who successfully completed
to capacitate young researchers with the knowledge and the ten-month Epidemiology Fellowship Program. Five
skills in conducting Epidemiologic research. fellows were given the Fellow in Epidemiology Award for
satisfactorily meeting the completion requirements, and
Started on 17 January 2022, the fellowship training two of the five fellows received an Excellence Award for
consisted of an online delivery of the instruction using their exemplary performance.
a modular approach. The teaching strategies included
lecture-discussion, in-class readings, session exercises
and discussion of the exercise answers, module quiz, and
research project with mentoring.

Building a critical mass of

researchers with required
knowledge and skill to
competently carry out
health research.
152 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 153

The PCHRD-TMC Physician-Scientist

Research Fellowship
Creation of a Pioneer Health Research Fellowship Program through a
Private Training and Research Hospital in the Philippines

The Medical City (TMC) established the Physician- effective cancer treatment for Filipino patients with
Scientist Research Fellowship (PSRF) Program, a relapsed/refractory B-cell malignancies, e.g. acute
pioneer research fellowship program in the Philippines. lymphoblastic leukemia and diffuse large B cell
The goal of PSRF is to develop physicians, the lymphoma, which are unresponsive to chemotherapy
next leaders of the country’s health research and with lower survival rates if managed with conventional
innovations, by giving them opportunities to conduct regimens.
research in their specialized fields of interest, while
continuing to serve their patients. Both fellows followed a timetable that includes the
research training administration modules, as well as
With the support from the DOST-PCHRD, the program guided mentorship sessions from November 2021 to
expands the country’s pool of health research August 2022 that were held via zoom calls and google
experts, who can solve the unmet medical needs of classroom sessions. The program was completed on
the Filipinos, guided by the National Unified Health 31 August 2022.
Research Agenda (NUHRA).
PSRF Program Year 1 Update and
In 2022, Dr. Gabriel Baluyut and Dr. Alma Calavera Milestones
are two fellows of the program. Dr. Baluyut’s research
entitled,“Artificial Intelligence Powered Chest X-ray To acknowledge the milestones of the first year of
screening for the clinical diagnosis of Osteoporosis,” the program, an event was held at Augusto Barcelon
aims to investigate the clinical utility of the Osteo-AI Auditorium in TMC last June 24, 2022. The event aimed
(pronounced Osteo-Eye) Deep Learning powered to highlight the partnership of DOST-PCHRD and TMC
chest x-ray screening tool for osteoporosis which is and the accomplishments of the two physician-scientist
tuned for the Filipino anatomy. Dr. Calavera’s research, fellows. It also aimed to inspire the young doctors in
on the other hand, is entitled, “Construction of CD19 training and practicing clinicians and specialists to
Chimeric Antigen Receptor T-Cells for Relapsed/ discover the exciting world of being a physician and
Refractory B-Cell Malignancies” which aims to make scientist at the same time.
154 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 155

CAPACITY BUILDING
In 2022, the team, headed by Dr. Divine Love Salvador
of UP Diliman, built a database for client pre- and
post-engagement assessment, and implemented UP

In 2022, five new capacity PsycServ’s key services. The project team also conducted
interviews with volunteer supervisors, psychosocial

building projects were

support specialists (PSSs), administrators of client units of
PsycServ’s learning programs, and PsycServ’s coordinator.
Among the accomplishments of the project include the

funded by the Council, seven conduct of the qualitative and quantitative analysis for pre-
existing data, integration of the quantitative and qualitative

ongoing projects are being

results of pre-existing data, and conduct of qualitative
analysis on the interview data.

monitored.
Health Technology Assessment Education: A
Series of Introductory Workshops

With the goal of educating stakeholders and the

NEW healthcare system on methodologies for producing Health

Technology Assessment (HTA) evidence and using HTA
evidence in decision-making processes, Dr. Teresa Luisa
Capacity Building Initiative for the the Kalinga Health private provider interface
G. Cruz of the UP Manila College of Medicine proposed
Philippine College of Emergency model of tuberculosis care in Metro Manila, the
the project entitled, “Health Technology Assessment
Medicine (PCEM) Residents, Fellows, Philippines.
Education: A Series of Introductory Workshops.”
and Consultants
Contextualizing PsycServ’s Ginhawa
In 2022, the first session of the two-day virtual training
Approved in November 2022, the project Model: Responding to the Challenge
of Integrating Mental Health and workshop was held last 24-25 November 2022. A total of
already started recruiting project team members
Psychosocial Support (MHPSS) into 63 people attended the training, which had nine sessions,
and project staff and held planning and initial
Higher Educational Systems seven lectures, and two workshops. The next series of the
coordination meetings for the capacity-building
workshop will commence in January 2023.
activities that will be conducted for the PCEM.
This initiative, headed by Dr. Jennifer M. Nailes This project is also one of the top innovations
recognized during the implementation of the Implementation of the Gelia Castillo Award
of the University of the East Ramon Magsaysay
2020 Gelia Castillo Award for Research on Social
for Research on Social Innovations in Health
Memorial Medical Center, aims to provide basic (GCARSIH) 2022
research methods (BRM) training for PCEM Innovations in Health.
residents, fellows, and consultants. Following its successful inaugural run in 2020, on 2 March
Based on its own Six-Component Ginhawa
2022, the Council approved the implementation of the
Valuation of a Novel Private Provider Model and with the goal of helping (future) client
Gelia Castillo Award for Research on Social Innovations in
Interface Model of Tuberculosis Care Higher Education Institutions (HEIs) integrate
Health (GCARSIH) 2022. This year’s GCARSIH included
in Metro Manila, the Philippines Mental Health and Wellbeing (MHW) into their
a training and mentoring package in partnership with
educational philosophy and system, PsycServ’s
Hybridigm Consulting, Inc.
The project is one of the top innovations key service and program offerings are replicated
recognized during the implementation of the to become sustainable and contextually relevant.
2020 Gelia Castillo Award for Research on This was done through closely supervised and
Social Innovations in Health. Led by Dr. Jason guided training in client-selected modules.
Alacapa of Innovations for Community Health,
Inc., the project aims to highlight the merits of
156 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 157

ONGOING
Data Analysis: A Conceptual Approach child health proposals. In 2022, the project launched a Call
for Proposals on Maternal Child Health and evaluated all
The project, led by Dr. Ofelia P. Saniel of UP Manila College the capsule proposals submitted. From the 48 proposals
of Public Health, aims to develop training modules on data received, 15 proposals that have been ranked the highest
analysis to be used by the RHRDCs in conducting the by the five (5) evaluators were selected. An orientation was
second part of the series of training activities on research conducted and a google classroom for the lecture videos
methods. and assignments of the proponents was created. The
project team is mentoring the proponents by conducting
In 2022, the team developed nine (9) prototype modules synchronous and asynchronous training via zoom on
and supplementary materials on data analysis, and different research methods topics.
conducted four (4) batches of training sessions using the
developed modules and materials. Training Workshops for the Technical Review
Boards (TRBs) of the Regional Health
To date,the nine (9) modules and supplementary materials Research and Development Consortia
on data analysis are currently being reproduced for
(RHRDCs)
distribution to the RHRDCs.
The DOST-PCHRD partners with the Foundation for
Capability Building Initiative in HIV the Advancement of Clinical Epidemiology (FACE) to
and Schistosomiasis: Mentoring and implement training workshops for the members of the
Development of Proposals Technical Review Boards (TRB) of the 17 Regional Health
Research and Development Consortia (RHRDCs). To
The Capability Building Initiative in HIV and determine the TRB members training needs a Training
Schistosomiasis: Mentoring and Development of Needs Assessment (TNA) survey was conducted.
Proposals project is led by Dr. Lydia R. Leonardo of UP
Manila College of Public Health. In 2022, the project A two-day virtual training workshop with the University
mentored eight (8) proponents from regions 7, 8, 11, 12, of the Philippines (UP) Manila Research Implementation
and BARMM. The project team provided assistance in the Development Office (RIDO) was held on 25-26 July 2022.
review, revision and improvement of capsule proposals Attended by more than 60 faculty members and Vice
and their development into full-blown proposals which Chairs for Research of UP - Philippine General Hospital, the
will be submitted for evaluation of funding agencies. training tackles topics on research methods and proposed
After internal and external reviews conducted, the eight RHRDC forms for use during technical evaluation.
(8) proposals on HIV and schistosomiasis were endorsed
Ending HIV transmission by Optimizing Pre- In 2022, the team has successfully implemented
to various Research Ethics Committees (RECs) for ethics On 18-19 August 2022, a face-to-face writeshop was
exposure prophylaxis in East Asia (HOPE) the following activities: a) signed memorandum of
evaluation. conducted to discuss and apply the revisions for the
understanding with three study sites in Mandaluyong,
TRB Manual of Operations. Meanwhile, the training
HOPE stands for ending HIV transmission by Optimizing Calamba, and Iloilo City, b) conducted a crowdsourcing
Research Capacity Building and workshop for the TRB members of Regional Health
Pre-exposure prophylaxis in East Asia. The HOPE logo contest as a “taster” of the crowdsourcing call for
Strengthening Initiative in Maternal and Research and Development Consortium XI (RHRDC XI),
innovations and to strengthen projects branding and
Network is a joint international initiative by public funding
Child Health: Mentoring and Development of Health Research and Development Consortium - Region
organizations in East Asia Summit member countries. identity, c) completed screening and final selection of
Proposals XII (HRDC-12), and BARMM Health Research and
This consortium is composed of the Monash University entries received from crowdsourcing contest to increase
Development Consortium (BHRDC) were held on 14-15
(Australia), the Institute of HIV Research and Innovation PrEP use, d) announced the top 10 winning entries in
The Research Capacity Building and Strengthening September 2022 at Apo View Hotel, Davao City.
(Thailand), and HOPE Philippines (HOPE PH), which is social media platforms. e) completed key informant
Initiative in Maternal and Child Health: Mentoring and
implemented by the Foundation for the Advancement interviews and focus group discussions among PrEP
Development of Proposals project is led by Dr. Jacinto Training for TRB members in Northern Luzon and National
of Clinical Epidemiology, Inc. (FACE, Inc) through the users and health care providers in the three study sites
Blas V. Mantaring III of Foundation for the Advancement Capital Region is set on the first quarter of 2023.
leadership of Dr. Nina Castillo-Carandang. The project’s (SAIL Clinic in Calamba, FPOP in Iloilo, LoveYourself, Inc.
of Clinical Epidemiology, Inc. The project aims to provide
overarching goal is to build a network of stakeholders that in Mandaluyong), and f) built the initial HOPE Philippines
capacity building training to researchers on maternal and
will promote the broader use of pre-exposure prophylaxis website.
child health and mentor the completion of maternal and
(PrEP) as a vital part of the armamentarium for preventing
and controlling HIV and AIDS.
158 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 159

BALIK SCIENTIST PROGRAM

2022 Balik Scientist Awardees (PCHRD) Tapping into the ingenuity

10 and expertise of Filipinos
Continuing and Ongoing Balik Scientists with Completed Engagements abroad to strengthen the
17 S&T capabilities of local
Continuing and Ongoing Balik Scientists monitored researchers in the academe,
24
public and private sectors,
and industry.

TOTAL EXPENDITURES IN 2022

PhP 18,910,598.56
160 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 161

PCHRD Balik Scientist Awardees in 2022

Dr. Myra O. Villareal Dr. Aloysius R. Domingo Dr. Ike C. de la Peña Dr. Thaddeus M. Carvajal
Bicol University UP-NIH Manila Adventist College DLSU Manila

Dr. Rose Constantino Dr. Gerard Dumancas Dr. Isaiah Paolo Lee Dr. June Bryan De la Pena
Cebu Normal University University of San Agustin UP Diliman Eastern Visayas Health Research
and Development Consortium

Building A Safer Future: VIP Balik Scientists These Balik Scientists‘ contributions and accomplishments
Exit Report Presentation in “Building a Safer Future” as advisors to the VIP were
recognized in the virtual Exit Report presentation held on
The current pandemic has brought to light the necessity 3 May 2022:
of having in-house virologists and a facility that will serve
Dr. Heidie Frisco-Cabanos as a meeting place for researchers working on human, • Served as bridges in forging collaborations with
Dr. Jennifer Yang
UP Manila
UP Manila animal, and plant virology. The DOST spearheaded the reputable virology institutions across the globe;
establishment of the Virology and Vaccine Institute of the • Opened the doors for opportunities for our budding
Philippines or the VIP. scientists to be trained and educated by known
virologists from institutions in various parts of the
Institutionalized through the Republic Act 11035, the Balik Significant outputs of the awardees included publication
Recognizing the road to VIP establishment is lengthy and world;
Scientist Program (BSP) aims to tap into the ingenuity of six articles in ISI/Scopus journals while 13 articles
laborious, seven virology specialists were engaged under • Helped promote the VIP and virology science to the
and expertise of Filipinos abroad to strengthen the S&T were pending for submission, preparation of three DOH-
the Balik Scientist Program (BSP), to support the VIP’s public, through the VIP Webinar Series. A total of
capabilities of local researchers in the academe, public FDA policies and guidelines on regulations for clinical
major initiatives carried out by the Industrial Technology over 10,000 people registered for the 21 installments
and private sectors, and industry. trial conduct and three manuals on regulatory practices,
and development of three curricula/modules for host Development Institute (DOST-ITDI). The following of this education and information campaign of the
As one of the implementing arms of the Department of institutions. virology specialists who shared their expertise were: Dr. VIP; and
Science and Technology, the PCHRD implements BSP Teodoro Fajardo Dr. Myra Hosmillo, Dr. Chrsitina Leyson, • Helped in the planning of the establishment of
to contribute to the identified health research priorities Dr. Elpidio Nadala, Dr. Leodevico Ilag, and Dr. Lourdes the VIP at the Clark New City in Capas, Tarlac by
included in the NUHRA and the HNRDA. Nadala, engaged with PCHRD. While Dr. Homer Pantua providing technical expertise in the facilities needed
was engaged with PCAARRD. by an institute as crucial as the VIP.
162 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 163

BSP Talks Webinar Series depending on their needs. Lastly, the BSP Secretariat Balik Scientist Program Orientation and In the needs assessment workshop, participants were
may assist in matching a prospective Balik Scientist Needs Assessment in CAR asked to identify institutional R&D thrusts, specify current
Following the success of the first episode in 2021, the with a potential host institution. programs and projects being implemented or proposed
DOST in collaboration with Pinoy Iskolars sa Korea To encourage various research and development or in the pipeline of their institutions, determine the highly
(PIKO) continued the conduct of BSP Talks, a webinar The third episode entitled, “Ikaw ang Hero Ko!,”held institutions (RDI) in Cordillera Administrative Region (CAR) specialized expertise lacking and needed, and identify the
series that aims to explain and demonstrate the Balik on August 30, 2022 is also broadcasted live on to become host institutions for Balik Scientists, the DOST- gaps to be filled by potential Balik Scientists.
Scientist Program (BSP) application process in a DOST-Balik Scientist Program Facebook page. The PCHRD conducted the “Balik Scientist Program and S&T
simple and creative manner. online webinar highlighted the testimonials of 10 Fellows Program Orientation and Needs Assessment
local researchers who acted as host scientists for our among RDI Networks in CAR” on June 24, 2022 at the BSP joins the National Science and
In 2022, two (2) BSP webinar series were conducted. Balik Scientists. They shared their experiences and Venus Parkview Hotel. Technology Week
The second episode entitled, "Match Tayo!" was the reasons why they consider our Balik Scientists
streamed live on the BSP Facebook page on 15 as modern-day heroes. With their testimonials, the Attended by 87 participants from various non-government The Balik Scientists Program took part in the NSTW
February 2022. This episode featured three ways a host scientists expressed their utmost gratitude for agencies, state universities and colleges, higher education celebration by having a booth where both students and
Balik Scientist can be matched with a host institution. the commitment and support of the Balik Scientists institutions, and members of the Cordillera Regional professionals could learn more about the Program. This
The first strategy showed successful matching who nurtured, strengthened and guided them in the Health Research & Development Consortia (CRHRDC), was done in alignment with the goal of highlighting
through active exploration of the aspiring Balik implementation of their R&D and technology transfer the event program tackled the benefits, privileges of BSP international S&T links. The games run by the BSP
Scientist of a potential host institution whose R and initiatives. It demonstrated the Balik Scientists’ vital host institutions as well as the application process. Another were played by both students and professionals. They
D priorities are aligned with his research interest. The role in nation building through the introduction of topic highlighted in the program was the presentation of distributed brochures and other materials.
second matching strategy is a host institution directly strategic technologies that help address pressing the accomplishments and the contributions of the Balik
reaching out and tapping a prospective Balik Scientist needs of the country. Scientists to the growth of host institutions in terms of
R&D interventions and innovation. The roster of Balik
Scientists who were previously and currently engaged
were also presented to the participating institutions.
 164 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 165

8th BSP Annual Convention

With the theme: “Balik Scientist: President Ferdinand Marcos, Jr.
Kasangga sa Paglinang ng Agham graced the occasion and delivered
at Teknolohiya para sa Maunlad the keynote address. A total of 162
at Matatag na Kinabukasan,” participants who joined the event
the 8th Balik Scientist Program were drawn from the program’s
Annual Convention was held on network of Balik Scientists,
14 October 2022 at the Philippine host institutions, stakeholders,
International Convention Center professional societies and
(PICC), Pasay City. organizations, international
partners and collaborators, and
The convention showcased local research communities.
the work of Balik Scientists in
a variety of fields, including The event was also broadcasted
agriculture, aquaculture, natural to recognize the Balik Scientists
resources, health, industry, energy, out of the country and the
and emerging technologies. It Host Institutions from different
also highlighted and recognized regions, and to involve potential
the crucial contributions of Balik participants to the Program,
Scientists to the Philippine nation’s prospective Balik Scientists and
advancement in both science and Host Institutions alike.
economy through their R and D
activities.
166 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 167

ETHICS

ACCREDITED RECs IN 2022

14 LEVEL 1
10 LEVEL 2
12 LEVEL 3

TOTAL EXPENDITURES IN 2022

The DOST-PCHRD values the well-being, dignity, and Week celebration entitled, “Measuring the Impact of
rights of human research participants in looking for CIDTA and CSA and the Role of its Partners in Achieving
science-based solutions for the health needs of Filipinos. the KPIs”, on 9 August 2022. It highlighted the roles of the
This is why forwarding health research ethics in the Committee on Information Dissemination, Training, and
country remains to be one of the major thrusts of the Advocacy (CIDTA) and the Committee on Standards and

PhP 4,862,097.51 Council. Accreditation (CSA) in achieving the goals of the PHREB
to promote, monitor, and capacitate functional research
The Philippine Health Research Ethics Board (PHREB) ethics committees (REC).
was created through DOST Special Order No. 091 s 2006
and institutionalized as a policy-making body through the Two simultaneous sessions of “Practical Training for
Philippine National Health Research System Act of 2013 REC Staff and Members” were also conducted on 10
(RA 10532) to “ensure adherence to the universal principles August 2022 via Zoom Meeting as a PNHRS Week Pre-

Ensuring adherence to the for the protection of human participants in research.” Conference Session. One of the training was facilitated
by Dr. Marita VT. Reyes and Dr. Angelica D. Francisco,

universal principles for

In 2022, guided by its mandates, the PHREB and the other one was facilitated by Dr. Sonia E. Bongala
led the development and launching of the and Dr. Fred P. Guillergan. Each training was attended by
2022 National Ethical Guidelines for Research REC Chair, Member Secretary, and Staff Secretary from

the protection of human

Involving Human Participants. selected institutional Research Ethics Committees. A total
of 75 participants attended the simultaneous training
The document, which guides all research stakeholders in sessions with 66 participants identified as researchers.

participants in research the ethical conduct of research in the country, was launched
on 16 March 2022 during a pre-conference session of
the DOST-PCHRD 40th Anniversary Celebration, after
In the same year, the PHREB accredited 36
Levels 1, 2, and 3 RECs, and assisted in the
conduct of 65 ethics training-workshops. The
achieving the PHREB’s approval, ad referendum, through
PHREB Resolution No. 001 on 01 March 2022. PCHRD also provides Secretariat support
to the National Ethics Committee, which
The PHREB also organized a session during the 15th accepted and reviewed 15 research protocols
Philippine National Health Research System (PNHRS) in 2022.
168 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 169

HEALTH RESEARCH The Council is currently giving

AWARDS four awards in health research.
DISTRIBUTION OF AWARDEES IN 2022 Alberto G. Romualdez, Best Mentor in Health
10 GCARSIH Jr. Outstanding Health Research Award
10 UNDERGRADUATE THESIS GRANTS Research Award
3 ORAL RESEARCH PAPER PRESENTATION COMPETITION (AROHRA)
Offered every three years, the award gives The Best Mentor Award is offered biennially to
recognition to a research program or project that has recognize and reward mentors in health research
demonstrated the link between research and practice who have built the capacities of researchers in the
TOTAL EXPENDITURES IN 2022
through the utilization of research findings in the health sector and, in the process, propelled significant
health delivery system. The award has two categories, advances in the PNHRS’ thrusts as identified in the
namely: Biomedical Research and Health Services National Unified Health Research Agenda (NUHRA).
Research.
In 2022, the Council conducted the awarding of
In 2022, winners of 2021 AROHRA were featured the 2021 Best Mentor in Health Research Award
during the Talakayang HeaRT Beat Press and launched the Call for Nominations for the
Conference on January 26, 2022. 2023 Best Mentor in Health Research Award.

PhP 831,527.67

DOST-PCHRD Gelia Castillo Award

Undergraduate Thesis for Research on Social
Grant in Natural Products
Giving recognition to The thesis grant provides fund support to all
Innovations in Health
(GCARSIH)
health researchers for
undergraduate students who will conduct their thesis
on natural products. It aims to sustain a research
culture in natural products to increase the number The GCARSIH is offered biennially to recognize

their exemplary research of research and later on build a pool of researchers/ the outstanding social innovations that
experts specializing in the field. address persistent, societal and health systems
challenges. Through the innovators’ experience,

efforts and contributions In 2022, the call for the 2022 DOST-PCHRD
Undergraduate Thesis Grant in Natural Products
we can better understand why and how social
innovations create impact and discover how to

in enhancing the country’s

was opened last 17 March 2022 during the PCHRD’s scale up these effective interventions.
40th Anniversary Celebration. A total of ten (10)
teams from Regions 3, 4A, 9, 10, 11, and BARMM In 2022, the Call for Applications for the

health research capabilities. were awarded with a thesis grant amounting 2022 GCARSIH was conducted. The winners
to PHP 50,000.00 The program also condcuted and finalists were awarded in the same
a virtual Oral Research Paper Presentation year. As an incentive, a seven-week training
Competition for the Grantees of the DOST-PCHRD and mentoring package on research grant
Undergraduate Thesis Grant in Natural Products application and proposal writing was also held
during the 15th PNHRS Week Celebration. virtually for the winners and finalists.
170 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 171

In 2022, 82 innovators participated in the The project known as ALAGA KA, or Alay sa Ginhawa
GCARSIH, which honors excellent social at Kalusugan, has been chosen as the overall winner of
innovations that solve enduring societal and the 2022 GCARSIH. The Health Futures Foundation, Inc.
healthcare system problems. The honor bears developed ALAGA KA with the goal of bringing healthcare
the name of Dr. Gelia T. Castillo, a prominent to underserved areas by constructing fully functional,
national scientist who stressed the value future-proof, and equipped barangay health stations
of scientific endeavors providing a societal
2022 Gelia Castillo Award for Research on
(BHS).
good.

The Philippines' healthcare system still faces difficulties

in providing patients with access to high-quality medical
With assistance from the governmental and commercial
sectors, the project team develops the BHS infrastructure, Social Innovations in Health (GCARSIH)
teaches local healthcare providers, and creates
care and sufficient medical supplies. A multidisciplinary
community-based health and wellness initiatives. In
movement called social innovations in health has recently
Batangas, Palawan, Samar, Northern Samar, and Eastern
arisen to address these prevalent and enduring health
Samar, ALAGA KA has handed over 23 barangay health
challenges. Social innovation in health is described as
stations thus far.
creative responses created and put into practice by a range
of players in response to a pressing medical need within a
Other GCARSIH awardees include:
specific geographic setting. With this method, healthcare
• Second Place: Culion Health, run by the Culion
is now more accessible, economical, and efficient. This
Foundation, came in second place for its network of
trend in the Philippines is heavily influenced by the Gelia
contracted TB clinics; and
Castillo Award for Research on Social Innovations in
• Third Place: The UP Surgical Innovation and
Health (GCARSIH), which in its first cycle in 2020–2021
Biotechnology Laboratory (UP SIBOL) Program, for
identified outstanding social innovations.
its joint effort on the production of complex, precise
medical equipment.
By tackling health issues, these social innovations—which
In addition to the winners, the Award recognized seven
were developed by Filipino social innovators for Filipino
finalists:
communities—have significantly impacted communities.
• Address the Stress: Mental Health 'Nudges' for
The GCARSIH aims to honor exceptional social innovations
Healthcare Workers' Wellbeing During the COVID-19
that tackle pervasive societal and healthcare system
Pandemic by AHA! Design for Behavior;
problems. It acknowledges that understanding how and
• Battle in the Blood (BitB), the University of the
why social innovations affect community health can be
Philippines Manila's first HIV gaming app;
improved via learning from the experiences of social
• CP Health Innovations, Inc.'s CareGO EMR, a
innovators. Additionally, GCARSIH aims to help social
vaccination management app;
innovators develop and scale their ideas so they might
• University Research Co., LLC's Community-Based
potentially be adapted to other areas with comparable
Drug Rehabilitation Treatment Intervention;
healthcare problems.
• CRAMMS and MATA+: The Provincial Government of
Tarlac's COVID-19 Risk Assessment, Monitoring, and
GCARSIH tapped the DOST-PCHRD and DOH national
Management Systems (CRAMMS) and Movement
networks to look for social innovations across the
Activity Tracker Application (MATA+);
nation. The Regional Health Research and Development
• Pediatric Childhood Cancer Patient Navigator
Consortium's main responsibilities included promoting
Program: Guiding Patients Through the Complex
the GCARSIH through its networks and determining the
Cancer Care Continuum, developed by the Philippine
regional eligibility of entries that were submitted. On 12
Cancer Society, Inc. in collaboration with the Philippine
August 2022, during the Closing Ceremonies of the 15th
Society of Pediatric Oncology; and
PNHRS Week Celebration, the winners and finalists of the
• Ugnayang Nanay, for enabling environment for
Gelia Castillo Award for Research on Social Innovations in
mothers, by Modern Nanays of Mindanao and ALIMA
Health fr the current year were announced.
Mother Support Center.
172 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 173

Awarding of the 2021 Best Mentor in Health Research Award

The Best Mentor Award is offered biennially to recognize and reward mentors in health research. By imparting
information and skills, instilling values and attitudes, and inspiring individuals participating in the research process,
research mentors help in fostering an enabling atmosphere and in turn, assist in building the capacities of researchers.

The following were awarded as cluster winners of the 2021

Training and Mentoring Package for the Winners and Finalists of the 2022 Gelia Castillo Best Mentor in Health Research Award during the Closing
Award for Research on Social Innovations in Health (GCARSIH)
Ceremonies of the 15th PNHRS week Celebration last
August 12, 2022:

Undergraduate Students Category

Luzon Cluster Rev. Fr. Alfredo V. University of Northern
Corpuz Philippines
Visayas Cluster Ms. Carol Joy P. Re- Aklan State University
maneses

Graduate Students category: Rev. Fr. Alfredo V. Corpuz

National Winner for the Undergraduate Students Category
Luzon Cluster Dr. Julius T. Capil Cagayan State Univer-
sity
NCR Cluster Prof. Agnes L. Llama- University of Santo
sares-Castillo Tomas
Visayas Cluster Dr. Rheajane A. Rosales Samar State University

The training and mentoring package for the winners and pitch, wherein the panelists acted as fund managers and Mindanao Dr. Mylene M. Uy Mindanao State Univer-
Cluster sity – Iligan Institute of
finalists of the 2022 Gelia Castillo Award for Research on evaluated the developed proposals based on both its Technology
Social Innovations in Health (GCARSIH) commenced last research merits and potential real-world benefits.
October 29, 2022. The training sessions, which are held Junior/Early-career researchers category
virtually via Zoom, ran for seven (7) weeks until December The project team will hold a culminating activity with
NCR Cluster Dr. Erna C. Arollado University of the Philip-
10, 2022. the 2020 and 2022 GCARSIH winners, together with an pines Manila
Inaugural Gelia Castillo Memorial Lecture in February Visayas Cluster Dr. Jonel P. Saludes University of San
Prof. Agnes L. Llamasares-Castillo
A panel presentation for the developed research 2023. Agustin
National Winner for the Graduate Students Category
proposals was also held last December 10, 2022. The
presentation simulated an evidence-based grant proposal
The National Winners for each category were then
selected among the Cluster Winners. The following are
awarded as the National Winners:

National Winners
Undergraduate Students Rev. Fr. Alfredo V. Corpuz
Category
Graduate Students Category Prof. Agnes L. Llamasares-Cas-
tillo
Early-career or junior Dr. Erna C. Arollado
researchers Category

Dr. Erna C. Arollado

National Winner for the Junior/Early-Career Researchers Category
1 74 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 175

2022 DOST-PCHRD Undergraduate The grant was awarded to the following undergraduate students from Regions 3, 4A, 9, 10, 11, and BARMM:

Thesis Grant in Natural Products Region 3

Shaira C. Gozun, Mark Kenneth S. Garcia, Alexandra
Undergraduate students conducting a thesis on natural products may be given financial support Kanela M. Sarcon, Ria A. Tabas Alexis, Domini D. Taberna,
through the DOST-PCHRD Undergraduate Thesis Grant in Natural Products. The Program’s objective Lorraine Rose Tongol, and Beatrice G. Villanueva
is to sustain a research culture in natural products to increase the number of research and, over time, Angeles University Foundation
develop a pool of experts in the field. The Program supports the Tuklas Lunas (Drug Discovery and “Biological activities of natural products from endemic
Development) program of the DOST-PCHRD, which aims to develop alternative medicines that are plants in Mount Arayat National Park (MANP) based on
safe, effective, and reasonably priced using the nation’s natural resources. phytochemical screening and virtual screening of related
homologs”
The call for the 2022 DOST-PCHRD Undergraduate Thesis Grant in Natural Products was opened
last 17 March 2022 during the PCHRD’s 40th Anniversary Celebration. The search was open to all Jherby Kyle C. Teodoro
undergraduate students of Colleges of Pharmacy, Chemistry, Nursing, and Health and Allied Sciences Nueva Ecija University of Science and Technology
who have thesis proposals on natural products, specifically utilizing indigenous plants in the region. “In-vitro Analysis of the Cytotoxic Activity of the Green
Synthesized Silver Nanoparticles Using Stem Barks of
Sandoricum koetjape n-hexane Extracts Against HCT-116
Cancer Cell lines”

Region 4A
Kristel Hope T. Villafuerte
University of the Philippines - Los Baños
“Biological Activities of Kombucha-Like Functional Beverage
from Insulin Plant (Costus igneus N.E.Br.) Leaf Tea”

Aaron R. Arasa, Hannah R. Natividad, and Kemp Christine

C. Sotelo
Southern Luzon State University
“Phytochemical and Pharmacological Profile of Tea Extracts
from Orthosiphon aristatus (Blume) Miq.”

Region 9
Binladen M. Daiman, Al-Ahmad B. Jaiyari, and Prinze
Rhadeen A. Kibong
Western Mindanao State University
“Antioxidant, Phytochemical and Cytotoxic Screening of
Cocoa Pod Husk (CPH) Extracts used as Herbal Tea”
 176 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 177

Oral Research Paper Presentation Competition for the Grantees of the DOST-PCHRD
Undergraduate Thesis Grant in Natural Products

Region 10 The Oral Research Paper Presentation Competition

1st place Jason C. Alcano Central Mindanao
Prince Eroll V. Reyes, and Emerson Paul D. Somontan for the 2019 and 2021 Grantees of the DOST-PCHRD University
Iligan Medical Center College Undergraduate Thesis Grant in Natural Products took
“Radioprotective Effects of Purple Yam (Dioscorea alata L.) place via Zoom on August 9, 2022. 2nd place Wenzel E. Perian Western Mindanao
State University
Tuber and Leaf Extracts on Genotoxicity Induced by X-rays in
Human Peripheral Blood Lymphocytes” The following winners were awarded on 12 August 2022, 3rd place Jerson Angelo Armecin Velez College Philip-
at the closing ceremonies of the 15th Philippine National pines
Aaron L. Degamon Health Research System (PNHRS) Week Celebration:
Mindanao State University - Iligan Institute of Technology
“Diabeathis”: In vitro screening of Clitoria ternatea (“blue
ternate”), Ficus septica (“Lagnob”), Heliotropium indicum
(“Elepante’), and Costus igneus (“Insulin plant”) as potential
source of Anti-diabesity agents”

Region 11
Raffy D. Cañeda
University of Southeastern Philippines
“Antibacterial and mutagenic activities of bioactive metabolites Jason C. Alcan Wenzel E. Perian Jerson Angelo Armecin
in the associated fungal endophytes of Lagnub (Ficus septica (1st Place) (2st Place) (3st Place)
Burm.) against Methicillin-Resistant Staphylococcus aureus”

Joshua M. Cambronero
University of the Philippines Mindanao
“Antioxidant and anticancer properties of Moringa oleifera
Lam stalk and stem bark extracts obtained by maceration
and ultrasound-assisted extraction”

BARMM
Alyana-Tajma Romato, and Rohaina Bayena
Mindanao State University-Main Campus
“Anti-hyperglycemic Effect of Torenia fournieri Linden ex. E.
Fourn. in Alloxan-Induced Albino Mice”
178 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 179

REGIONAL HEALTH
RESEARCH AND Regional Research Fund improve their competency in designing, implementing,

DEVELOPMENT CONSORTIA
and managing health research projects. Once the
Beginning researchers are given support to enhance their researcher was able to establish a good track record,
skills in conducting health research aligned with NUHRA he/she will then be encouraged to apply for the larger

AND REGIONAL RESEARCH or the Regional Unified Health Research Agenda (RUHRA)
through the Regional Research Fund (RRF) Initiative.
scale research project/program grants also available in
DOST-PCHRD, DOST, Department of Health (DOH),
Commission on Higher Education (CHED), and other

FUND The Regional Research Fund (RRF) initiative aims to

encourage beginning researchers to be actively involved
national and international funding agencies.

in health research activities without competing with For 2022, the DOST-PCHRD monitored seven new and
experienced researchers. Under the RRF initiative, 42 ongoing projects. A total of four projects were also
beginning researchers can then gain experience that will completed for the period.
Regional Health Research and operations of the RHRDCs, as well as support for the
Development Consortia (RHRDC) critical components of the research management
program.
In line with the thrust of developing and encouraging Newly-approved RRF Projects in 2022 LIMPIO: Lessening Infestation of Microbes and
institutional research activities, and in the interest of Institution development programs of the Council Parasites through Interventions in Open-field farms
equity, the Council organized the Regional Health have zeroed in on institutions with existing in Marilog District, Davao City
Epidemiology of Zoonotic Toxoplasma gondii
Research and Development Consortia (RHRDCs). potentials for health research activities, and in the Dr. Aleyla E. de Cadiz
Infection Among Household Cats in Region X
establishment of regional systems through the University of the Philippines Mindanao
Dr. Kassey Alsylle Talle Dargantes
The Consortia serve as the structures through Consortia.
Central Mindanao University
which institution development programs are to be Water Quality Assessment and Evaluation of Human
implemented and as a mechanism to encourage In 2022, the DOST-PCHRD supported 16 RHRDCs Health Risk in Selected Rivers of Lanao del Sur,
Exploring Antimicrobial Medicinal Plants used by
and promote health research activities in the regions. through its Grants-in-Aid Program. Philippines
Indigenous Natives in Two Mountain Ecosystems of
Bukidnon, Philippines (EXAMINE Bukidnon) Dr. Annabella G. Villarino and Prof. Nourshamsia C. Barosa,
The Council’s institutional development package in Dr. Mark Lloyd G. Dapar Mindanao State University Main - Marawi Campus
the regions includes administrative support for the Central Mindanao University
Physical Activity of the Elderly in the 4th District of
The Lived Experiences of COVID-19 Survivors in Leyte amidst COVID-19 Pandemic
Northern Mindanao Ms. Maria Elisa A. Caberos

Encouraging beginning researchers

Dr. Lourlyn P. Mansaguiton Palompon Institute of Technology
Mountain View College
Predictors of Clinical Outcomes of COVID-19

to be involved in health research Development of a Cost Effective HPLC-FLD

Analytical Method for the Quantification of Residual
Confirmed Adult Patients Hospitalized in Eastern
Visayas Medical Center
Fluoroquinolones in Chicken and Pork Dr. Jose Carlo K. Del Pilar

activities without competing with Dr. Erwin Oliver V. Fundador

University of the Philippines Mindanao
Eastern Visayas Medical Center

experienced researchers.
180 PCHRD ANNUAL REPORT 2022 P APRATR 1T: 2R:EISNESATRI T
CUHT A
IONN
D D
DEEVVEELLO
OPPM
MEEN
NTT 118811

Quantification of Antibiotic
Resistance Genes of
Enterobacteriaceae from
an Organic Farm and their
Products in Benguet
182 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 183

COMPLETED RRF PROJECTS IN 2022

In vitro and In Vivo Anti- solution; 2. A. macrorrhiza showed inhibition of HMG-
Quantification of Antibiotic Resistance Completed in June 2021, the project was able to isolate hypercholesterolemic activity of Alocasia CoA Reductase confirming its anti-hypercholesterolemic
Genes of Enterobacteriaceae from an resistant bacteria from poultry manure, soil, and from the macrorrhiza (Araceae) and its Food Products potential. However, its inhibition is lower than the
Organic Farm and their Products in Benguet leaves of the vegetables that were planted on the farm Darwin A. Garbeles commercial drug pravastatin; 3. A. macrorrhiza showed
Dr. Roland M. Hipol at Longlong, La Trinidad, Benguet. Five species belonged Partido State University anti-hypercholesterolemic potentials by lowering the
University of the Philippines-Baguio to the Enterobacteriaceae family, most of which were levels of triglycerides, high-density lipoprotein (HDL), low-
Bacillaceae representatives. The results of this study According to the World Health Organization (2016), density lipoprotein (LDL), very-low-density lipoprotein
One of the most prevalent problems faced by rural farmers are significant because they offer a peek at the level of three-quarters of CVD deaths take place in low- and (VLDL), and total cholesterol of hypercholesterolemic
in the country is antibiotic resistance contamination in antibiotic resistance contamination on a farm in Benguet, middle-income countries like the Philippines. Therefore, mice models.
upland farming. This research aims to assess the prevalence which may also be the situation on other farms in the area there is a great need for the development of innovative
of antibiotic resistance genes of Enterobacteriaceae using the same upland farming techniques. treatments from natural sources and food from underused The project was able to provide nutritional and
isolated from an organic farm and their products as well as crops that have fewer negative side effects than current pharmaceutical validation of A. macrorrhiza corm extract
identifying the foodborne pathogens present in an organic Farm owners will have a view of the impacts of excessive pharmaceuticals. and food products. The study will augment the importance
farm and their products. use of antibiotics which can serve as a guideline in of this underutilized plant material which is found endemic
reducing antibiotic administration in livestock. Local The study generally aimed to evaluate the anti- in the Bicol Region.
The study used molecular techniques to amplify and health officials can utilize the information acquired to hypercholesterolemic activity of the crude extracts and
detect DNA in order to identify the isolated bacteria and disseminate information on health risks, while LGUs food products from the corms of Alocasia macrorrhiza. Through the Council’s RRF program, Partido State
identify the genes responsible for antibiotic resistance. can use it to develop policy directives for encouraging a University served as the implementing agency, while the
Utilizing ImageJ software, the relative quantification of healthier environment and ensuring food safety. Upon completion of the project, the data on the anti- Bicol Consortium for Health Research and Development
the antibiotic resistance genes was carried out, and the hypercholesterolemic activity of A. macrorrhiza has (BCHRD) and the Department of Science and Technology-
information produced by this research will be useful to been fully gathered and analyzed. The key findings are V (DOST V) served as the monitoring agencies for the
the local farmers. Owners of organic farms can take the as follows: 1. A. macrorrhiza showed high phenolic and implementation of this project.
necessary precautions to reduce the spread of these flavonoid content in ethanolic solution than aqueous
infections.
 184 PCHRD ANNUAL REPORT 2022 PA R T 2 : I N S T I T U T I O N D E V E L O P M E N T 185

Ultrastructural Characterization of Snail-associated Factors Associated with Acceptability of Mass

Digenic Parasites in Rice fields Surrounding Lake Drug Administration for Morbidity Control of
Mainit, Philippines Schistosomiasis
Dr. Joycelyn C. Jumawan Ms. Nathalie C. Fat
Caraga State University Father Saturnino Urios University-College of Nursing

The project aims to identify digenic parasites isolated from snails and This study found that providing data on the behavioral impact
bovine feces through ultrastructural characterization. Specifically, of Mass Drug Administration in Schistosomiasis endemic
the study aims to: 1) Provide an updated inventory of gastropods areas of Butuan City will provide a foundation for enhancing
inhabiting rice fields of Lake Mainit; 2) Isolate digenic parasites from advocacy and health promotion and education efforts that
snails and bovine feces from the identified areas; and 3) Prepare will help increase MDA coverage for more effective morbidity
isolated parasites for light and scanning electron microscopy. The control.
study will also determine the prevalence of Schistosoma infection
in rice fields adjacent to Lake Mainit by collecting Oncomelania The project aims to describe the Mass Drug Administration
hupensis quadrasi snails and bovine fecal samples which are then for Schistosomiasis management in Butuan City, to
subjected to laboratory examination and analysis. determine the profile of the respondents, to identify factors
associated with Mass Drug Administration to help achieve
Completed on 20 June 2022, this project was implemented in the target coverage for morbidity control, to determine the level
following target sites surrounding the Lake Mainit rice fields of Brgy of acceptability of Mass Drug Administration for morbidity
Cuyago in Jabonga, Agusan del Norte, Brgys Alipao and Poblacion control in Schistosomiasis, and to determine the correlation
in Alegria, Surigao del Norte, and Barangays San Isidro, Magpayang, between the profile of the respondents and the factors
and Matinao in Municipality of Mainit, Surigao del Norte. described.

The results formulated an updated inventory of snails (9 species) The project’s continuation assisted the researcher in
in relation to the soil and water characteristics of the rice field. A conducting research with the goal of providing substantial
research article regarding this is already undergoing peer-review research-based data or information about health, specifically
for publication. 100% of the parasites from snail individuals and in factors associated with the acceptability of mass drug
bovine feces were also isolated from the rice field stations. Seven (7) administration for schistosomiasis in the COVID-19 context in
parasites were documented from bovine feces from the six (6) rice Butuan City, Philippines.
field stations. Incidences of multiple parasite infections in bovines
from rice fields adjacent to Lake Mainit were also observed. Eight (8) The output of the research project will provide data or
digenic trematodes from snails were identified, and seven (7) of these information on the ground to the Department of Health,
are first reported in the Philippines. Soil and water features of the rice Butuan City Health Office, Public Health Nurses and
fields of Lake Mainit were characterized, and its physicochemical Midwives, and schistosomiasis endemic communities
parameters were analyzed. An article regarding this is also under regarding the implementation of one of the schistosomiasis
review containing the major findings. ITS sequences from isolated controls and elimination strategies during the COVID-19
cercaria were already deposited in GenBank, and a paper was pandemic. Because it used a mixed method of research, the
published in two (2) journals – the Journal of Parasitic Diseases and study’s findings are applicable to a larger group of people in
the Asian Journal of Biological and Life Sciences. similar situations.
186 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 187

PART

3
PCHRD supports translation of research to
policy to deepen public understanding, and
engages stakeholders in the research RESEARCH
UTILIZATION
dissemination processes. It also advances
technology adoption by guiding researchers,
technology transfer officers and industry
partners as they go through each step of
idea generation to utilization.
188 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 189

Talakayang Health Research and Technology (HeaRT) Beat

The Talakayang HeaRT Beat (THB) is a press conference series launched by the DOST-PCHRD in 2019 to share the latest
updates in health research and to facilitate dialogues between health research stakeholders, the media, and the greater

COMMUNICATION
Filipino community. The name HeaRT Beat stands for Health Research and Technology Beat. The conference has been
a platform for our local scientists to share exciting developments on their projects and experiences. This year, 11 sessions
(10 virtual and 1 hybrid) of THB were organized by PCHRD.

ACTIVITIES Date Topic

No. of
Viewers/
Participants
Facebook in-
sights
Participant’s Event
Rating

26 January Health Research Awards 114 - Zoom 2,213- Reach 97.60% rated very
895 - FB 62- Engagement satisfactory and higher
Support to Research Dissemination
24 February Tuberculosis Research 153 - Zoom 2,494-Reach 100% rated very
The Council supports projects and activities on events, two for paper presentation, and one for material 999 - FB 65-Engagement satisfactory and higher
research dissemination, including, but not limited to development.
support to publication, paper presentation, and events. 31 March Fellowship in Epidemiology 112 - Zoom 1,693- Reach 92% rated very
A total of 3.18 million pesos were provided for this 980 - FB 86- Engagement satisfactory and higher
In 2022, the Council approved twelve (12) requests for program.
Support to Research Dissemination (SRD) of which
20 April Prospective Urban and Rural 106 - Zoom 2,363- Reach 100% rated very
five were requests for publication, four for scientific Epidemiologic (PURE) Study 1159 - FB 105- Engagement satisfactory and higher

5 17 June eHATID 113 - Zoom 10,.564- Reach 97.30% rated very

4 2941 - FB 506- Engagement satisfactory and higher

24 June Startup Research Grant 148 - Zoom 2,071- Reach 97.60% rated very
857 - FB 49 Engagement satisfactory and higher

2 1 28 July Regional Research Fund 49-Zoom 2,444-Reach 97.14% rated very

810-FB 80-Engagement satisfactory and higher

Paper Scientific Publication Material 16 September Prospective Urban and Rural 106-Zoom 1,799- Reach 94.32% rated very
presentation events Development Epidemiologic (PURE) Study 632-FB 55-Engagement satisfactory and higher
Session 2
29 September Telehealth R&D 135-Zoom 2,988-Reach 94.9% rated very
930-FB 89-Engagement satisfactory and higher

28 October Undergraduate Thesis Grant 72-Zoom 2,228-Reach 100% rated very

on Natural Products 806-FB 85- Engagement satisfactory and higher

25 November Biomedical Devices Engi- 52-Face to face 864- Reach 96.30% rated very
neering for Health attendees 72- Engagement satisfactory and higher
27,417- FB
 190 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 191

Visualize Health Research 2:

Make your life better: Visual Abstract Contest
A digital campaign With the goal of reaching a wider audience in the dissemination of research results of its supported projects
in Twitter and Facebook, the DOST-PCHRD conducted the Visualize Health Research 2.0: A Visual Abstract
Contest. Contestants chose a research study from one of the published PCHRD-supportant projects from 2019
to 2020 and created a visual abstract.

Out of more than 70 submissions, three were selected as winners of this competition.

12.3M 35.11 3.03M 56K 1.3K 2.3K

Campaign Campaign Campaign Post Post Link clicks
Reach Impressions Video Views Reactions shares

FIRST PLACE SECOND PLACE THIRD PLACE

Angel Leah Delos Reyes Gaid Nicole Olive Agbuya Coquia Salma Khairia A. Alang
Mindanao State University- Saint Louis University Laboratory University of Immaculate
Iligan Institute of Technology High School - Senior High Conception
(MSU-IIT)
For the first time, the DOST-PCHRD implemented a digital lift rate at 10.37%. The post was also shared over 700 times
campaign entitled, “Make your life better,” to increase which gave the brand exposure outside of the main target A Social Media Contest was also launched wherein the visual abstract poster entry with the highest number of reactions
awareness about the DOST-PCHRD and its role and market. and shared posts will be awarded the People’s Choice Award.
contribution in the field of health research that positively
benefited the Filipinos. All three video materials were highly watched and engaged
with by the audience. View-Through Rates (VTRs) continued
The campaign produced three video materials (30s, 15s, to be high and costs were conservative until the end.
6s edit down) and 5 static posters to be disseminated in
Facebook. The campaign was launched during the PCHRD’s The audience continued to resonate with the promoted posts
40th Anniversary celebration on 17 March 2022 and lasted as seen by the consistent engagement rate across all posts.
until June 2022. All posts had a significant number of shares that exposed the
posts to an audience beyond the target market.
The overall campaign was able to reach 12, 308, 482 unique
users, delivered 2, 774, 764 video views, and garnered In terms of demographics, engagements consistently came
3, 049, 280 post engagements on Facebook. from the older generation and mostly female while there’s a
higher chance of ad recall lift within the younger users and
The Reach and Frequency posts had consistent performance male audience. Almost 100% of engagements came from
as seen by their ad recall lift rate. Of all the posts, it was Tawa- mobile devices.
Tawa that resonated most with the audience given its higher PEOPLE’S CHOICE AWARD PEOPLE’S CHOICE AWARD
Yoela Grace P. Baltazar Rendel Icee V. Ramos
Saint Louis University Saint Louis University Laboratory
High School - Senior High
192 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 193

Social Media Media Mileage (January to August 2022)

The Council utilizes social media platforms such as Facebook and Twitter to reach more Filipinos with accurate and To understand how the media perceives the Council, media mileage was used as a monitoring tool to track and analyze
updated health research information. data on all major social platforms.

Facebook
As of Dec 2022, the DOST-PCHRD TELEVISION RADIO
Facebook page has over 75,000
followers. We are also able to reach
over 34 million users and make over
a million engagements.
85 1.6M 93 5.6M
Coverages Viewership/ Broadcasts Viewership/
Readership
Readership

Twitter
As of Dec 2022, the DOST-
PCHRD Twitter page has over
3,100 followers. There are a total of
500, 000 impressions and 17, 000
engagements. PRINT ONLINE

58 61.6M 306 542M

Appearances Viewership/ Posts Reach
Readership
 194 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 195

The National Research and Development Conference

(NRDC) is a yearly activity that aims to promote coordination
2. Shining the Light on Liver Cancer: CANDLE Study
Program
7th National Research and Development Conference (NRDC)
and collaboration among stakeholders of research and 3. Chemical and Biological Characterization of Pure
development (R&D) and innovation. It highlights ongoing and Bioactive Compounds from Kadios (Cajanus cajan)
completed R&D projects and programs that are aligned to Seeds and its Topical Formulation Studies
the priority areas of the Harmonized National Research and 4. Development of Anti-inflammatory Herbal Products from
Development Agenda (HNRDA) that will be for the use or Iluko Indigenous Plants (MMSU TLDC )
benefit of society, and those that may contribute to economic 5. Field Implementation of a Locally Developed Diagnostic
development. Kit for the Detection of CoronaVirus Disease-2019
(COVID-19)
With the theme "Sustaining the R&D Momentum for 6. Relationship of Body Composition to the functional
Prosperity and Wealth Creation," the event highlighted the Capacity and Quality of Life of Older Filipinos in Selected
role of science and technology in developing innovations to Provinces in the Philippines
support industry, especially the micro, small and medium- 7. Two-stage, Randomized, double-blind, placebo-
sized industries (MSMEs). controlled clinical trial on the efficacy and safety of
Lagundi (Vitex negundo) tablets/syrup (NIRPROMP
During its celebration on 15 and 16 September 2022, the DOST- formulation) with standard treatment compared to
PCHRD presented the current updates of HNRDA for Health. placebo with standard treatment in patients with mild
Aside from this, the Council invited nine program leaders who COVID -19 disease without comorbidities
presented their research projects at the conference, namely: 8. CRISPR-based Diagnostics (CRISPR-Dx) for the
Detection of SARS-COV2 and TB
1. POWer: Mobile Biomedical Device Unit to Enhance 9. eHATID (Android-based electronic medical record
Access to Prosthesis and Orthosis Devices system for LGU)
 196 PCHRD ANNUAL REPORT 2022 PP
AARRTT 3 3: R
: ERSEESA
ERAC
RHC HU T
UITLII LZIA
ZTAITOI N
ON 119977

National Science and Technology Week (NSTW) DOST@64: Gabi ng Parangal at Pasasalamat
After two years of online celebrations, the face-to-face Along with several participating agencies, the exhibit The Council participated in the DOST@64 Gabi ng Parangal
conduct of the National Science and Technology Week showcased health-related research technologies and at Pasasalamat, an activity under the Department of Science
(NSTW) was held on 23-27 November 2022 with the theme projects. Among the Council-supported projects displayed and Technology's 64th Anniversary.
"Agham at Teknolohiya: Kabalikat sa Maunlad at Matatag na are the Biotek M Dengue Aqua Kit by Manila HealthTek Inc.,
Kinabukasan." the Cementless Hip Replacement System by Orthopaedic Held on 13 June 2022 at the Sofitel Philippine Plaza Manila,
International Inc., the LISA Robot by the University of Santo the event recognizes lead partners of DOST in the various
President Ferdinand "Bongbong" Marcos Jr. graced Tomas, and more. sectors, including health for their significant contributions
the celebration as keynote speaker during its Opening towards the advancement of Science and Technology in the
Ceremonies where he expressed support for the Philippine Over 2725 attendees visited the Health Cluster exhibit. country.
S&T community.
During the awarding, the Vaccine Expert Panel (VEP), a
With the theme "Pananaliksik Pangkalusugan: Tugon sa group of infectious disease experts working closely with the
Pangangailangan ng Kinabukasan," the DOST-PCHRD led COVID-19 Task Group on Vaccine Evaluation and Selection
the 2022 NSTW Health Cluster Exhibits. headed by the DOST, was recognized for guiding the S&T
sector towards safe and effective COVID-19 vaccines. In
addition, DOST-PCHRD partner institutions and supported
projects were also recognized for their contributions in health
through research.
 198 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 199

18th National Biotechnology Week (NBW)

The National Biotechnology Week is celebrated every year 22 November 2022 via Zoom. The webinar aims to increase
by virtue of Presidential Proclamation No. 1414. Led by the awareness on the current HIV situation in the country and
Department of Trade and Industry (DTI), this year’s celebration showcase how research on biotechnology can help build the
banners the theme: “Responding to the Challenges: Business country’s capacities against the disease.
Opportunities in Biotechnology.”
HeaRTNovation: Advancing Technology
This year’s celebration is a combination of face-to-face events Transfer in Biotechnology
held at the Philippine Trade Training Center (PTTC) and online
events hosted by different agencies from November 21 to 25, Recognizing the challenges researchers face when
2022. In support of the NBW, the Council participated in the bringing health research outputs to the market, the DOST-
physical exhibit at the PTTC and hosted two webinars which PCHRD supports researchers and institutions in advancing
highlighted PCHRD-supported projects on biotechnology. technology transfer. Led by the Council’s Intellectual Property
and Technology Management (IPTM) unit, several programs
HeaRT Report: Overcoming HIV through are implemented to support the market launch of health
Biotechnology research outputs.
To help address the burden of HIV in the country, the DOST-
PCHRD supports projects dedicated to the disease, such During the NBW, the Council also conducted the
as generating awareness, developing diagnostic kits, and “HeaRTNovation: Advancing Technology Transfer in
looking for possible treatment options. Biotechnology“ webinar to provide a platform for discussion of
the challenges, opportunities, and best practices researchers
Parallel to this commitment, the Council conducted the HeaRT can adopt in commercializing biotechnology outputs.
Report: Overcoming HIV through Biotechnology webinar last
 200 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 201

18th National Medical Writing

Workshop

In partnership with the Philippine Association of Medical

Journal Editors (PAMJE), the DOST-PCHRD conducted the
18th National Medical Writing Workshop on 8-12 August 2022
virtually. This writing workshop aims to help young researchers
in health sciences acquire practical knowledge and writing
HeaRT Report: Low-Cost the sustainability of its implementation in the Philippines.
Initial results of the project showed that carbon dioxide
skills in developing scientific articles for publications in
scholarly peer-reviewed journals. This batch was
Ventilation System to decrease (CO2) emissions go directly to the ventilation system,
which decreases the risk of spreading the virus indoors. The Among the lessons taught are structure and individual
risk of COVID-19 airborne current prototype utilizes readily-available materials such components of a scientific paper, process of preparing a
are organized, well-written, and have the greater potential
transmission as PET sheets, cable ties, duct tape, and glue to enable manuscript, and the role of editors and peer reviewers and
to get published in peer reviewed journals. Winners are Dr.
easy deployment. Approximately, one unit of the prototype what they look for in a manuscript.
ventilation system is projected to cost Php 5,000, of which Roger Junior C. Colobong of University of the East Ramon
Launched to showcase the results of its supported Health Magsaysay Memorial Medical Center, Mr. Ryan Christopher
Research and Technology projects, the Health Research and the cost is expected to significantly go down after negotiation Under the guidance of the faculty and mentor-facilitators, the
with suppliers and manufacturing partners. C. Lao of UP Manila, Dr. Franz Michael M. Magnaye of
Technology (HeaRT) Report’s first session was held on 29 14 participants had the opportunity to review and revise their
Philippine General Hospital and Dr.Margarita Katrina Amor D.
July 2022 at the Radisson Blu Hotel, Cebu City. manuscripts.
With the installation of the local prototype in multiple Tan of Chinese General Hospital and Medical Center.
Organized with the University of San Carlos (USC), DOST
Region 7, and the Max Planck Institute for Chemistry (MPIC) classrooms in Cebu last May, the project team is now gearing At the end of the workshop, the "Most Ready to Publish Paper
in Germany, the HeaRT Report featured the DOST-PCHRD- to further test the effectiveness of the ventilation system Award" was given to four participants whose papers
supported project on Low-Cost Ventilation System. prototypes with real students during face to face classes,
and assess whether the use of the ventilation system will
Developed by Dr. Frank Helleis of the MPIC, the ventilation cause any degree of discomfort among its users. Following
system is used in more than 600 schools in Germany the American Society of Heating, Refrigerating and Air-
to decrease the risk of COVID-19 airborne transmission. Conditioning Engineers (ASHRAE) Standard 55-2020, the
Following Dr. Helleis’ design, the USC aims to develop a local team will consider the following parameters: air temperature,
version of the system, demonstrate its effectiveness within a mean radiant temperature, air speed/velocity, relative
tropical indoor setting, assess its performance, and evaluate humidity, clothing insulation, and metabolic rate.
202 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 203

22
RESEARCH TO
POLICY
Inputs to Policymaking

The Council participated in formulating policy • Senate Resolution on Pandemic Resiliency

policy inputs in 2022
recommendations and instruments to support the • UHC Strategic Policy Framework and Plan
following legislations in 2022: • Guidelines on the Implementation of the DOST
• Bills Regulating Practice of Microbiology in the Science and Technology (S&T) Fellows Program
Philippines and its Detailed R&D Proposal
• Bills Regulating Practice of Physical Therapy in the • Medical Reserve Corps
Philippines • Establishment of the Center for Disease Prevention Introduction to Evidence-Informed Policymaking for
• Philippine Nursing Act and Control Health: 3rd DOST-PCHRD Webinar/Workshop for
• Philippine Physician’s Act • Virology Institute of the Philippines Early-Career Researchers (HIV)
• Science Communication Agenda • National Institute for Science and Mathematics
• National Innovation Centers of Excellence for Education Development (NISMED) Act Evidence-informed policy-making is the application of the best
Science and Technology (NICEST) • An Act Establishing the Forensic Science Institute available research to support policy formulation and decision-making
• 2021 PIDS Survey of Innovation Activities (PSIA) in the University of the Philippines System (WHO). On the one hand, it involves the systematic generation,
• Program/Project Leadership of S&T Fellows and • Medical Cannabis Compassionate Access Act of translation and dissemination of knowledge and information from
Use of DOST-GIA Funds the Philippines research, ensuring that facts and evidence are made available in a
• Promoting One Health Education in Thai Border • Waste to Energy Act timely and useful manner. However, on the other hand policy-making
Schools • Center for Disease Control and Prevention Act is an inherently political process involving various actors, competing
• Reduction of Indirect Cost interests, limited time and resources, and other political considerations.
• Conceptual Zero Draft of WHO A basic understanding of the political economy, e.g. the relationships
between individuals, government, and public policy, provides a lens
that can empower researchers to effectively navigate this environment
and advocate to decision-makers and the wider community of
stakeholders.

The goal of the webinar is to cover the basics of translating research

into policy and equip researchers with a better understanding of the
research ecosystem specific to HIV.

The webinar was opened to the public via social media and geared
towards college and graduate school students, health researchers,
research managers, health program managers, health advocates, and
others who may be interested in evidence-informed policymaking in
HIV. The webinar was broadcasted live thru DOST-PCHRD’s Facebook
page where it had a cumulative view of 675, Facebook reach of 1,520,
and a total of 95 Facebook Engagement as of 30 May 2022. Additionally,
the Zoom webinar had a total of 361 participants.
 204 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 205

3-Minute Pitch to Held during the 15th PNHRS Week last August 10, 2022,
Policymakers’ Competition nine participants from the Regions: 1, 2, 3, 4-A, 6, 9, 11, 12 and
CARAGA presented their completed research in a three-
A successfully completed health research study, especially minute, one-slide presentation to a non-specialist audience.
with substantial results, must be communicated to The winners of the competition were:
policymakers and key stakeholders to empower decision
3MP Winners (15th PNHRS Week)
making. It is important for researchers to know how to
1st Place Dr. Marjorie Nolasco Region 3
communicate research findings to inform and share
evidence to policy makers. This activity aims to serve as an
2nd Place Prof. Jennifer Luyun Region 2
exercise and cultivate researchers’ academic, presentation,
and research communication skills to influence policy. 3rd Place Dr. Benneth Mercado Region 12

Introduction to Evidence- Held last 27-29 July 2022 at the Philippine International
Convention Center (PICC), Pasay City, Manila, the workshop
Informed Policymaking for had a total of 15 early-career researchers from the Luzon
Cluster. On the other hand, the three-day workshop for
Health: 3rd DOST-PCHRD Visayas and MIndanao clusters was conducted last 16-18
Workshop for Early-Career November 2022 at Seda Hotel, Iloilo City. The workshop had
a total of 14 early-career researchers.
Researchers
The workshop included presentations on the fundamental
In its third year, the DOST-PCHRD webinar and workshop concepts underlying the political economy of health, the
series for early-career researchers was envisioned to provide application of strategic communication for policy advocacy,
a platform for capacity and community building among and examples of best practices for evidence-informed
the country’s health science researchers and contribute policymaking. The participants were able to recognize the role
to strengthening the Philippines’ policy environment for of political factors and effective communication in translating
health. The overall objective of the workshop series is to raise research outcomes into policy.
awareness and understanding among research stakeholders
of the contribution of evidence to policy making, build the Aside from the lectures, the participants had the opportunity
capacity of early-career researchers to effectively advocate to participate in the small group mentoring led by the
for evidence-informed policymaking at different levels of workshop directors to support them in the development of
government, and provide opportunities for co-learning and their policy advocacy road maps and “pitch” to policy makers.
mentoring. The participants also had the privilege of meeting a local
policymaker for a roundtable discussion on the dynamics of
policymaking at the LGU level.
206 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 207

Intellectual Property and

Technology Management

The Council aims to ensure that health With this, the IPTM developed the
research outputs will be essentially HeaRTNovation that would ensure
used to help the Filipino people that these health research outputs are
Programs under HeaRTNovation
with their daily lives. The PCHRD protected, assessed, and eventually
guarantees this through its technology
transfer arm, the Intellectual Property
utilized/commercialized properly. In
2022, the IPTM was also awarded
IPROTECH TEKI in Health SGP
and Technology Management (IPTM), funding support amounting to Intellectual Property Technology Transformation and
which oversees the utilization of health P2,621,828.00 for the HeaRTNovation Protection and Empowerment of Knowledge Startup Research Grant
research outputs generated from Hubs Program, which will be formally Management of Health Generators and Innovators in Program
research projects that are either funded launched in 2023. Research Outputs Health PrograM
or monitored by the Council.

This year, the PCHRD rebranded its

technology transfer initiatives into an
umbrella program called HeaRTNovation.
HeaRTNovation monitors the
development of health research outputs
47.82 million total expenditures in 2022

and provides support for each step of the

technology transfer process. STATUS OF PROJECTS

8 NEWLY-APPROVED

11 COMPLETED
24 ONGOING
34 PROPOSALS PROCESSED
 208 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 209

TEKI IN HEALTH
Impacting Every Juan's Health University Innovation Fellows
through Technology Transfer (UIF) for Health
(Phase 2):

Building a stronger market-ready IP Portfolio from are as follows: (1) 1/1 journal article published; (2) 3/3 PCT Dr. Bienvenido S. Balotro. all of which are undergoing approval.
UP Manila DOST-Funded Technologies applications filed; (3) 2/5 local patent applications filed; and The University Innovation Fellows (UIF) for Health is a Similar to FEC, Siklab also uses the principles of customer
(4) 9/10 business plans drafted. PCHRD-funded project that intends to establish and discovery and industry interviews.
Impacting Every Juan’s Health through Technology Transfer In line with the project, UPM-TTBDO intends to strengthen implement a tailored training program in entrepreneurship
is a PCHRD-funded project that aims to strengthen UP UPM’s IP portfolio by prosecuting the registration of the and innovation leadership for researchers of health-based Siklab, in addition, incorporates Intellectual Property and
Manila’s IP portfolio of DOST-supported health technologies IP applications filed from their Phase 1 project, subjecting technologies. Specifically, UIF for Health is a training program Technology Transfer principles. UPSCALE offers capacity-
in preparation for technology transfer. It was approved for market-ready health technologies under IP valuation and that aims to assist health innovators in bringing their health building workshops and mentorship to early-stage
implementation for a period of 15 months (approved duration: freedom-to-operate (FTO) search, enhancing their respective technologies to the market. technology startups. It also provides networking, investment
January 2022 - December 2022; 1st approved extension: business plans, and filing additional health technologies that and grant facilitation, coworking space and back office
January - March 2023). need immediate IP protection. These activities form part of This program is based on the combined essential components support, and access to university facilities, expertise, and
UPM-TTBDO’s overall plan of bringing UPM-generated of the Filipinnovation Entrepreneurship Corps (FEC), UP equipment. In addition, UIF for Health also covers topics on
The University of the Philippines Manila - Technology Transfer health innovations in the market. Siklab (Saliksik Laboratory), and UPSCALE Innovation regulatory processes/FDA approval requirements and spinoff
and Business Development Office (UPM-TTBDO) leads Hub’s best practices. FEC is an experiential lean startup mentoring.
the monitoring, utilization, and commercialization of health The project has an approved budget amounting to PhP training program designed to help researchers determine
technologies generated by UPM researchers. 4,950,799.84 and is currently implemented by the University the commercial readiness of their research projects through The TEKI IN HEALTH - University Innovation Fellows (UIF)
of the Philippines Manila - Technology Transfer and Business customer discovery and research validation. for Health project was approved for implementation for a
In 2022, the team’s key achievements under the project Development Office (UPM-TTBDO) under the leadership of period of 21 months (initial duration: Sept 16, 2021 – Sept 15,
Key accomplishments of the project team this year include the 2022; 1st approved extension: Sept 16, 2022 - Dec 15, 2022;
following: (1) drafted 4/4 prior art search reports, (2) drafted 2nd approved extension: Dec 16, 2022 - June 15, 2023). It has
5/4 freedom-to-operate reports, (3) developed 7/7 minimum a budget amounting to PhP 4,995,654.40 and is currently
viable products (MVPs), (4) created 11/7 health venture teams, implemented by the University of the Philippines Diliman -
(5) conducted 34 industry mentor interviews, (6) delivered UPSCALE Innovation Hub under the leadership of Dr. Luis
11 pitch presentations to industry, and (7) facilitated 4/4 Sison.
research service agreements (RSAs) with industry partners,
 210 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 211

Startup Research
Grant Program HeaRTNovation Portfolio This year, there are 41 technology briefs uploaded in
PCHRD’s HeaRTNovation innovation portfolio and a total
The HeaRTNovation Portfolio highlights the Council’s
of 52 intellectual property (IP) applications were filed to the
highly valued health research outputs from health research
Intellectual Property Office through funding support from the
partners and institutions that showcases PCHRD-
Council.
supported technologies which are ready for adoption, pre-
Enhancement of the Design and Field Testing of an The Pivotal Peak Digital Health Solutions, Inc. commercialization and full-commercialization.
electronic referral (e-Referral) system for Service (PPDHSI) won the Best Startup of the Year
Delivery Networks (SDNs) in support of UHC Award in the Health Sector during the 64th DOST
Anniversary.
In 2019, the UHC law was signed as a government mandate
to ensure that every Filipino shall receive a full spectrum of Based on the study’s results, the evidence-based studies HeaRTNovation Talent During the three-day event, the IPTM Philippine Health
Research Innovations Matching Event (PHRIME) was also
health services and affordable health benefits. on the effectiveness of eReferral systems to improve
communication between primary care and specialists is
Development and Information conducted with around 12 potential partners and investors.
Through PHRIME, they met with the lead researchers of the
Among the features of the UHC Law are the expansion of
population, service, and financial coverage through an array
encouraging. Dissemination Institute of Biomedical Engineering and Health Technology
of health system amendments (DOH, 2019). Considering (IBEHT) to discuss how the research outputs and innovations
The PPDHSI was the first spin-off company of the UP Manila, The IPTM unit regularly conducts capacity building and
the breadth and challenges in coordination and patient can further be developed to reach the market. Four projects
and the licensee of the Community Health Information information dissemination activities. In 2022, there were eight
referrals to various health offices, evidence-based studies on teams launched their innovation portfolio and met with
Tracking System (CHITS). The R&D team is led by the CEO, Capacity Building/Training and eight Info Dissemination
the effectiveness of electronic referral (E-Referral) systems prospective partners from the production and manufacturing
Mr. Arturo M. Ongkeko, a registered nurse by profession and activities conducted by IPTM.
to improve the communication between primary care and sector, other related industries and government agencies,
was awarded with Distinction in Academic Excellence as a
specialists is highly relevant to support the provisions of the namely:
De La Salle University Institute of Biomedical Engineering
UHC law.
and Health Technologies (DLSU-IBEHT), with support iFall device – a wearable device for fall detector system, pre-
from the DOST-PCHRD, held a virtual conference entitled and post-fall heart rate, and blood pressure measurements
In 2015, the National Telehealth Center (NTHC) of the
TeknoLunas: the 1st Philippine Biomedical Engineering and Portable Multi-Sensor System for Sweat – a wireless
University of the Philippines Manila implemented an initial
Health Technologies Conference and Exhibit. multi-sensor system that has the capability to analyze
prototype of an E-Referral system in the Community Health
Information Tracking System (CHITS) EMR called the “Mag- measurements in sweat such as glucose, lactate, potassium
TeknoLunas centers on the theme, “Commercializing and sodium as well as sweat rate and temperature
Ina Telereferral System (MInTS)”.
biomedical devices and health technologies for an inclusive SiglaVent – an Innovative Automated Ambubag intended
and innovative Philippines”. It highlighted the importance to be used for patients requiring brief durations of assisted
The project supported by PCHRD aims to design and develop
of commercialization and utilization of biomedical devices ventilation
a two-way electronic referral system for service delivery
and health technologies, making these accessible to their 3D printing and Additive Manufacturing for Biomedical
networks (SDNs) in support of Universal Healthcare (UHC)
beneficiaries while also promoting inclusivity and innovation. Devices – emphasized the important and growing role of
to improve the initial E-Referral system prototype and expand
its use-case to facilitate referral of emerging and re-emerging additive manufacturing in the biomedical sector.
Fulbright and CHED scholar.
communicable and non-communicable diseases. This will
improve and streamline the communication among primary Dr. Miguel Sandido Albije serves as the project manager. He is
care physicians, specialists, and health providers involved in a mechanical engineer and a physician from the UP College
a patient’s care. of Medicine. DOST-PCHRD has provided funding support to
the startup company, as well as opportunities to join and be
featured in international networking sessions with investors
both from the Philippines and foreign countries.
212 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 213

INFORMATION
PRODUCTS AND HERDIN PLUS: Strengthening
SERVICES
Department Philippine Health Insurance Corporation. The
orientation included discussion about the features of the
partnerships and building HERDIN PLUS, account creation, research forms, and
document delivery requests.
capacities
The IPS also conducted HERDIN PLUS Learning Sessions
This year, the Health Research and Development online which were attended by representatives from
The Council aims to increase access to health research information through its Information Network Platform of Unified Research colleges, universities, and hospitals. The learning sessions
Information Products and Services (IPS) unit which offers access to information Information Management Systems (HERDIN PLUS) aim to prepare research-generating institutions to share
systems and platforms. It also provides services such as Document Delivery Service focused on enabling researchers, faculty, and students to their research outputs to the Council’s information system
e.g HERDIN PLUS Learning Session and Orientation and capacity building to provide use the Council’s information system and introduce how and platform that is in compliance with copyright law and
assistance to institutions in managing/organizing their health research information. it is being used to manage and disseminate their health best practices in data protection and open access.
and health-related research information such as research
2022 HERDIN PLUS new records uploaded abstracts, journal articles, undergraduate and master Overall, HERDIN PLUS was able to conduct 21 online
theses, among others. learning sessions and four onsite session in Western
224 Mindanao State University on 18 July 2022.
184 HERDIN PLUS organized a series of orientation online
173 which was attended by Cebu South Medical Center,
91 127
Our Lady of Fatima University, and Corporate Planning
92
184 97

65
54 54
30

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

580K HERDIN PLUS

Website visits in 2022

858
HERDIN PLUS full-text
request and inquiries
served

25 HERDIN PLUS
Learning Sessions
214 PCHRD ANNUAL REPORT 2022 PA R T 3 : R E S E A R C H U T I L I Z AT I O N 215

HERDIN PLUS Learning Sessions Conducted

DATE INSTITUTION NAME

July 5, 2022 MCU Hospital – Filemon D. Tanchoco Foundation

July 6, 2022 Philippine Children's Medical Center

July 7, 2022 Governor Celestino Gallares Memorial Hospital

July 14, 2022 University of San Jose - Recoletos

July 18, 2022 Western Mindanao State University

July 21, 2022 West Visayas State University Medical Center

July 26, 2022 University of San Carlos

August 1, 2022 Universidad de Sta. Isabel

August 4, 2022 Ateneo de Zamboanga University

August 17, 2022 Cardinal Santos Medical Center

August 18, 2022 Trinity University of Asia

August 23, 2022 Far Eastern University – Dr. Nicanor Reyes Medical Foundation

September 2, 2022 Ospital ng Makati

September 5, 2022 Cebu Doctors' University

September 7, 2022 UERMMMCI

September 8, 2022 Bataan Peninsula State University

October 3, 2022 Cebu Normal University

October 13, 2022 Mountain View College

October 20, 2022 Our Lady of Fatima University

November 15, 2022 Philippine Rice Research Institute

November 16, 2022 Region II Trauma and Medical Center

November 24, 2022 Philipine Heart Center

November 28, 2022 Philippine Obstetrical and Gynecological Society

December 6, 2022 Central Mindanao University

December 7, 2022 MSU-Gen San

216 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 217

4
PART The Council
values national
and international
partnerships in
health research and
development.
COLLABORATIONS
It continues to forge
collaborations with
health, research, and
academic institutions
to bring forward
its mission as the
leadcoordinating body
for health R&D
218 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 219

National Collaborations

Philippine Primary Care Studies Rapid Review of the Evidence on Prioritized

Dr. Antonio Dans COVID-19 Technologies and Intervention
Sagip Buhay Medial Foundation Dr. Marie Carmela Lapitan
University of the Philippines Manila
Advancing Health through Evidence-Assisted Decisions To provide information on current primary health care
with Health Policy and Systems Research To address the burdens of COVID-19 on Filipinos and the
systems, a project by Dr. Antonio Dans of the Sagip Buhay
Medical Foundations, Inc. aims to determine the impact of an constantly-evolving research evidence on interventions to
outpatient primary care strengthening system on health care address the pandemic, a review of the current evidence is
delivery. The project specifically studies a decentralized PHC critical to contribute to the effective management and control
The Advancing Health through Evidence- 2021 AHEAD-HPSR Program components
system in selected locations in the country. of the disease in the country.
Assisted Decisions with Health Policy and of the Department of Health (DOH) which
Systems Research (AHEAD-HPSR) program tackle health financing, human resource
In 2022, the project recruited doctors and health professionals Under the leadership of Dr. Marie Carmela Lapitan of the
is a DOST-PCHRD partnership with the management, health service delivery, health
to provide primary healthcare at the chosen study sites University of the Philippines Manila, the DOST-PCHRD
Philippine Health Insurance Corporation governance, and health economics. Eight (8)
in Samal, Bataan, and Bulusan, Sorsogon. Trainings and supports a project that aims to generate systematic
(PhilHealth) which forwards research and component projects were implemented and
workshops were conducted among the healthcare providers reviews and evidence summaries on prioritized COVID-19
development as a tool to strengthen local two (2) are already completed. These projects
as well. The team also engaged with private laboratories and technologies and interventions.
health systems and policies. are expected to have at least one (1) policy
pharmacies and established a public-private network for
brief and will directly impact the DOH’s needs.
healthcare providers for the communities. Integrating eHealth Outputs of the project guided medical management, ensure
The program aims to: The program’s plans and objectives for the CY
into PHC, the team setup telemedicine systems in all the study effective public health intervention and maximize efficient
inform the health sector’s global and national 2023 include the implementation of the 2022
sites in coordination with the respective barangay offices. use of limited resources would be informed by the evidence
administrative and legislative policy agenda AHEAD-HPSR program. In 2023, the AHEAD-
To date, the project has published 3 papers in local journals summaries.
create an equitable and enabling environment HPSR program will focus on research priorities
and 1 in an international journal.
for health policy and systems researchers all that are deemed necessary to support policy
Through the project, the team was able to come up with
over the country development for research management
The immediate end-users of the project (during the pilot recommendations on the use of COVID-19 vaccines for
position the Philippines as a contributor to the and the ethics review process in the DOH.
studies) are the primary care facilities in the University of children as well as pregnant and lactating women, the use of
regional and global health systems knowledge Similar to the previous AHEAD programs, the
the Philippines Diliman, both private and public primary heterologous vaccines, boosters, and the efficacy of vaccines
program is always expected to provide policy
care providers in Samal, Bataan, and in Bulusan, Sorsogon. against variants of SARS-CoV-2. Aside from vaccines,
In its current and latest cycle, the program inputs and recommendations.
Meanwhile, the medium to long-term end-users after the pilot the team also reviewed antigen testing, antibody testing,
focused on the implementation of selected
studies are the policymakers, health planners including the prognostic models, and carbon dioxide monitors.
DOH, PhilHealth, and local governments who will implement
the UHC Law, including the Provincial and City Health Boards. Policies and guidelines of DOH agencies may be impacted
by the evidence summaries. Project outputs and final
recommendations are posted on the COVID-19 Living
Clinical Practice Guidelines (LCPG) website (https://www.
psmid.org/philippine-covid-19-living-recommendations-3/)
and the Health Technology Assessment Unit (HTAU) website
(https://hta.doh.gov.ph/assessments/) for public access.
220 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 221

The Philippine Health Insurance Corporation satisfaction, policy goals, inpatient care, review of
(PhilHealth) has been implementing strategies and claims, and accreditation mechanisms, among others.
programs to achieve Universal Health Care (UHC) Aside from R&D, the program also supported a six-
since its establishment in 1995. In 2014, PhilHealth month training course entitled, “Capacity-Building
promulgated the Governing Policy on Research Program on Implementation Research for PhilHealth
Engagement Guidelines and established the Regional Offices and Technical Staff in PhilHealth
PhilHealth Research Agenda centered on generating Head Office: Local Evidence to Advanced Decisions
knowledge for health policy reforms in pursuit of (LEAD).” The activity equipped PhilHealth technical
Universal Health Care. To carry out the PhilHealth staff with necessary skills and knowledge to formulate
Research Agenda, the Corporation partnered with policies guide by research. A total of 9 capstone
the PCHRD the following year to implement the papers were produced from the training.
PhilHealth STUDIES Program, which stands for Lastly, one of the highlights of 2022 was the PhilHealth
“Supporting the Thrust for Universal Health Care STUDIES Virtual Forum held on 9 - 10 November
through Data, Information, and Knowledge Exchange 2022 at the Philippine International Convention
Systems.” Center, Pasay City with the theme “Health Financing
in Post-Pandemic Times: Exploring New Theories
The program is dedicated to developing evidence- and Practices to Advance UHC.”
based policy reforms for PhilHealth programs and
services by funding research studies and other S&T The two-day forum centered on ensuring financial
activities related to the fields of health economics protection for vulnerable sectors, expanding health
and social health financing. In 2022, the program service coverage, and re-examining policy reforms
supported the conduct of research projects, for Universal Health Care (UHC). It aimed to formulate
conducted capacity building activities, organized evidence-based recommendations and strategies for
a research forum, and completed a research forum improving the National Health Insurance Program by
documentation project. The partnership will continue assessing the lessons learned from the COVID-19
until 2023 to further attain its objectives of providing Pandemic. The event also featured capstone research
quality social health insurance coverage. projects of the 2022 Local Evidence to Advance
Decisions (LEAD) Capacity Building Program and
Consistent with its mission towards health policy the studies generated from the PhilHealth Research
reforms, the research projects supported under LAB.
PhilHealth STUDIES covered studies on client
222 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 223

International Collaborations
Agency for Science, Technology, and
Newton Agham Programme Research (A*STAR) - Singapore
Cycle 2 The Council participated in the Innovation Mission in Singapore for the
The Newton Agham Programme is part of the UK’s Newton establishment of HeaRTNovation hubs in the Philippines, through the A*STAR,
Fund Programme, which is an Official Development Assistance particularly its Diagnostics Development Hub (DxD Hub).
to the Philippines aimed at developing science and innovation
partnerships to promote economic development and welfare. The Innovation Mission in Singapore was a two-day benchmarking activity
with the primary objective of exchanging information on the best practices and
Government Agencies of the Philippines were identified as key programs for establishing technology business incubation (TBI) hubs in the
strategic partners for the Newton Fund. In 2015, the Medical healthcare institution setting.
Research Council (MRC) of the UK and PCHRD of the Philippines
identified several areas of synergy and joint strategic interests, This is aligned with the objectives of NEDA-DBM Innovation Fund approved
and held a joint call for health proposals in order to support project titled, "Establishment of PCHRD Health Research and Technology
research and innovation collaborations between the scientists Innovation Hubs (HeaRTNovation Hubs): Expanding the TEKI in Health
from the UK and the Philippines through the Newton Agham Program among Health Institutions," implemented by the Philippine Council for
Programme. Health Research and Development in support of R.A. 11293 otherwise known
as the Philippine Innovation Act. The project aims to develop a new model of
The PCHRD and the MRC have been in partnership to jointly technology business incubation different from the existing innovation or TBI
implement research collaborations on Communicable and Non- program of the other two DOST Councils as the target institutions' strength and
communicable diseases of relevance in the Philippines. This capacity is on health innovation.
partnership under the ‘Newton Agham’ has resulted in a total
of 12 collaborative projects approved between 2015 to 2018, With the Council set to launch its HeaRTNovation Program in 2023, learnings
amounting to over Php 200 million. To date, the program provided and insights from this Innovation Mission helped develop the framework and
funding to projects focused on topics such as Dengue, Malaria, guidelines in the implementation of the PCHRD HeaRTNovation Hub program.
AMR, TB, HIV, Schistosomiasis, Rabies, Zoonotic Diseases and
Diabetes. This programme also enabled partnerships with During the first day of the Innovation Mission, the Council met with the
various UK institutions namely: Liverpool School of Tropical representatives from DxD Hub’s Clinical Laboratory led by its Vice President
Medicine, Wellcome Sanger Imperial College, Imperial College for Outreach and Talent, Ms. Yuan Lu Ho, where she discussed Singapore's
London, University of Bristol, The London School of Hygiene & commitment to sustain investments for Research, Innovation and Enterprise
Tropical Medicine, University of Glasglow, University of Surrey, which encompasses its RIE2025 plan. Under the Human Health and Potential
Queen’s University of Belfast, and University of Cambridge. RIE2025 domain, platforms and organizations that will drive innovation and
translation of technologies were established to create value for Singapore's
The continued success of the partnership involved close enterprises. The Council was also introduced to Co11ab, Singapore's First
coordination between PCHRD and MRC-UKRI in identifying Biomedtech Incubator Embedded within a Health City, in a meeting with
research priorities for funding, streamlining the proposal review A*StartCentral.
process between the agencies, and monitoring ongoing projects.
Cycle 2 projects not only focused on Infectious Disease research, To witness and learn from their best practices, the Council was able to visit the
but also enabled opportunities for partnerships on topics on A*STAR SIMTech Innovation Factory on the second day. It is a center dedicated
Non-communicable diseases like Diabetes. to support Singapore's SMEs from ideation to the design and engineering stage,
allowing them to venture into higher value markets. It also caters to the needs of
its member companies by design capability building which eventually ensures
successful market entry. The delegates from the PCHRD also had an opportunity
to meet with A*STAR consultant, Dr. Sidney Yee about the development of the
framework for the HeaRTNovation Program.
 224 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 225

ASEAN Diagnostics Initiative (DxI)

Diagnostics Development Hub Singapore Submission of new proposals for funding from the level of R&D up to technology transfer and/or pandemic, and it was very unfortunate that the pandemic
commercialization or business development. has reversed much of the progress that we have achieved
On 18-23 July, the Council worked with the Diagnostics Proposed governance and restructuring of ASEAN Dxl through the years before the pandemic. The challenges of
Development Hub (DxD Hub) Singapore, its co-lead Strategic Planning Panel (SPP) (A revised governance 7th World One Health Congress developing resilient health systems remain, and a whole-of-
partner agency in the ASEAN Diagnostics Initiative (DxI), in structure was formulated to streamline decision-making for society approach is key to addressing these challenges.
developing strategic programs and activities in the area of the ASEAN Dxl. Briefly, proposed revisions in the governance The Council attended the 7th World One Health this year
diagnostics between Philippines and Singapore. structure are as follows:) which features in parallel the Pinnacle Series sponsored by During the closing ceremony, the WOHC laid out what’s
Temasek Foundation. The Series is a three-day programme next for One Health Agenda which includes investment
During the first two and a half days, the representatives from 1. PH & SG will be co-leads (country leads) for ASEAN Dxl that aims to increase awareness on preparedness to combat in prevention, the need to work across different sectors of
the council and DxD Hub were able to discuss and finalize the to chair the Programme Steering Committee (PSC). public health threats in Southeast Asia, which is a regional society, effective promotion and communication of One
activities for the ASEAN DxI Working Session and Strategic 2. Programme Steering Committee will comprise a hotspot for emerging infectious diseases. Health approach, among others.
Planning, programme agenda, and project proposals which nominated Steering Committee member from each AMS
were presented to Dr. Jaime C. Montoya and Dr. Sidney Yee & ASEAN Secretariat. The Pinnacle Series has five tracks, namely, Infectious Disease Aside from the WOHC, the Council was also present during
of ASEAN DxI. 3. The PSC will advise on ASEAN Dxl priority projects Threats in Southeast Asia (AMR), Scientific Evidence for the 6th ASEAN Serosurveillance Study (ASSeSS) Principal
and nominate Key Opinion Leaders (KOLs) as project Pandemic Communications (PEB), Pandemic Preparedness Investigators' Meeting on 10 November at the Singapore
The following plans and activities were formulated for the advisors/investigators on a per project basis. and Health Systems Resilience (PPHSR), One Health Science Botanical Gardens where principal investigators from each
coming year: (OHS) and Impact on and Innovations in Clinical Practice of the participating countries, namely, Indonesia, Malaysia,
ASEAN Dx Initiative Special Meeting (IICP). Thailand, Vietnam, Philippines, and Singapore, gave updates
ASEAN DxI Plans and Activities for 2022 - 2023 on the status of the serosurveillance study in their respective
Phase 2 ASEAN Serosurveillance Project (ASSeSS Study) Dr. Jaime Montoya delivered a talk under the PPHSR track,
On the last day of the working session and strategic planning, countries. The meeting also served as an opportunity to
Dr. Montoya delivered a talk on the role of PCHRD in fostering along with invited speakers from the ASEAN Diagnostics learn best practices on implementing multi-site international
1. Expansion of the study to involve the four remaining AMS
innovations to define the future of diagnostics in increasing Initiative, on transformative innovations toward pandemic research from the different study sites in ASEAN.
(Cambodia, Laos, Myanmar, Brunei)
awareness of the current activities of DOST-PCHRD in support preparedness. Experiences, initiatives at the local, regional
2. Additional studies for seroprevalence pre- and post-
of research, development and innovation for diagnostics and and national levels, and best practices were shared in the In addition to this, the ASEAN Diagnostics Initiative, headed
booster dose administration, long-term immunity
other technologies, and to encourage future collaborations session, which allowed participants to learn applications by the Philippines and Singapore, also gathered stakeholders
determination and detection of antibodies against
with DxD Hub. The major programs/priority research and innovations which can be adopted and adapted in their through a hybrid meeting in A*Start Central on 11 November.
different SARS-CoV-2 variants using a multiplex assay
areas were tackled, as well as the different mechanisms by own communities or localities. He also shared the success Several matters were discussed, particularly on how to move
3. Timelines and resources needed
which PCHRD and DOST support technology innovations in achieving the UN Sustainable Development Goals (SDGs). forward with the initiative, including the composition of the
It was startling to learn that we will not be able to reach strategic planning or steering committee.
the SDGs on the target period even without the COVID-19
226 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 227

Fondazione Italiana Fegato (FIF)

During the visit, a scholars forum was conducted Liver Network was emphasized, focusing on
to provide a platform for current scholars to present Hepatitis, Cancer, and Fatty Liver diseases as main
their outputs. Dr. Inah Marie Aquino and Dr. Eric priority areas.
David Ornoso presented their research results.
While Ms. Kay Cabral, third year PhD student, A courtesy call was made with the Italian
presented some updates on her and Dr. Noel ambassador H.E. Marco Clemente. Prof. Tiribelli
Salvoza’s accomplishments and milestones. shared the partnership between FIF and DOST-
PCHRD which began in 2019, what has been
Several meetings with representatives of the achieved, and future goals. DOST-PCHRD
University of Trieste (UNITS), Filipino Scholars, submitted an article for inclusion in the coffee
future of liver collaboration, board of FIF, University table book souvenir for the 75th anniversary of
of Pisa, key officials from Italy’s Ministry of University the diplomatic relations between Italy and the
and Research were also conducted. The DOST Philippines.
delegates were also able to pay courtesy calls to
Regional Government Authorities, Office of the Prof. Tiribelli also met with the Hepatology Society
Mayor (Trieste), and Philippine Consulate General of the Philippines, represented by Dr. Mara Panlilio.
in Milan. Discussions were made on the collaborative efforts
spearheaded by FIF, PCHRD, and UPM, which
should be announced in national conferences held
Visit in Manila
annually to encourage involvement of MD-PhDs,
clinicians, gastroenterologists and nutritionists.
In 2019, DOST-PCHRD signed a Memorandum of will promote joint research efforts and capacity- Prof. Claudio Tiribelli of FIF visited Manila last
This was shortly followed by a meeting with MD-
Understanding (MOU) with Fondazione Italiana building initiatives on liver research both for Filipino September 6-8, 2022 to attend various meetings
PhD scholars interested in doing liver research
Fegato (FIF) to work on the following areas of and Italian researchers. One of the main outputs with key stakeholders. The first meeting was with
through a sandwich program at FIF.
collaboration: 1) establishment of the Philippine to be expected is the organization of the Philippine UP Manila (UPM) and the National Institutes of
Liver Network; 2) implementation of a graduate Liver Network composed of Filipino academic and Health (NIH), where the roadmap on Network
A quick meeting was also held with USec. Beverly
studies program (PhD in Molecular Biomedicine) research institutions. Development for the next six years (2022-2028)
Ho of
at the University of Trieste (UNITS) with research was discussed. The establishment of the Philippine
training from FIF; 3) enhancement of the Research
Visit in Italy
Fellowship Program; and 4) Sandwich Research
Training in FIF for the current MD-PhD in Molecular
The DOST Delegation went to Italy this year to
Medicine scholars.
assess the current capacity building program
being implemented at the University of Trieste and
Last year, DOST-PCHRD and FIF, signed another
University of Pisa and FIF, conduct meetings with
MOU with University of the Philippines Manila (UP
key stakeholders, and developed plans for the liver
Manila) to formalize the parties’ commitment to
collaboration.
advance liver research in the Philippines. An offshoot
of the existing cooperation, this tripartite partnership
228 PCHRD ANNUAL REPORT 2022 INSIDE PCHRD 229

Financial
Highlights

INSIDE
General Administration and Support
Php 33,095,604.68

S&T Services Research and Development

Php 54,606,663.06 Php 478,128,929.31

PCHRD
Capacity Building
Php 125,434,558.46

Expenditures in 2022
Source: General Appropriations from Government and
Grants-in-Aid

Operations
Php 70,208,430.02
 230 PCHRD ANNUAL REPORT 2022 INSIDE PCHRD 231

PCHRD received its CSC-approved Merit Selection Plan guidelines

On 14 September 2022, the Civil Service Commission (CSC) ensures that there will be no discrimination in the selection
approved DOST-PCHRD’s Merit Selection Plan guidelines, a of employees on account of gender, civil status, disability,
systematic method of assessing and selecting employees on religion, ethnicity, or political affiliation. It is the policy of the
Resource Mobilization the basis of their relative qualifications and competence to PCHRD to strictly adhere to the principles of merit, fitness,

PCHRD Status of Funds 2022 perform the duties and responsibilities of the position. and equality. The Plan covers career positions in the first,
second and third levels, as well as non-career positions in
PARTICULARS ALLOTMENT EXPENDITURES UTILIZATION Recognizing the importance of equal employment opportunity PCHRD.
RATE for men and women at all levels of the position in the Council
General Appropriation from Government (GAA-RA No 11465) provided that they meet the minimum requirements, PCHRD
General Administration and Support 38,607,310.00 33,095,604.68 85.72%
Operations 76,124,900.00 70,208,430.02 92.23%
Grants-in-Aid 664,572,000.00 658,170,150.83
Research and Development 478,128,929.31 478,128,929.31 100.00%
Capacity Building 125,434,558.46 125,434,558.46 100.00%
S & T Services 61,008,512.23 54,606,663.06 89.51%
Total Fund from National Government 779,304,210.00 761,474,185.53 97.71%

Funds from Other Sources

FUNDING SOURCE/PROJECT TITLE AMOUNT* EXPENDITURES UTILIZATION
RATE
DOH - 2021 Advancing Health Through Evidence Assisted 46,479,566.95 29,635,417.46 63.76%
Decisions with Health Policy and Systems Research Program
DOH - 2018 Advancing Health Through Evidence Assisted 48,752,157.49 9,918,442.56 20.34%
Decisions with Health Policy and Systems Research Program
PCHRD opens door for Pisay students in science immersion program
DOST - Balik Scientist Program 5,400,787.83 3,581,359.55 66.31% The PCHRD hosted 22 scholars from the Philippine Science activity organized by the PSHS that aims to develop science
DOST - Addressing and Responding to COVID-19 through 5,097,383.42 1,419,993.54 27.86% High School (PSHS) CALABARZON regional campus in a research laboratory skills among their students, as well as
Health Research (ARCHER) Science Immersion Program (SIP) on 4-22 July 2022, which help identify and formulate research problems for their future
DOST - Creation of Tuklas Lunas Program Management Team 71,000.00 71,000.00 100.00% enabled the high school students to be exposed to ongoing research work.
DOST - Indirect Cost of Various Projects 46,875,559.81 19,864,715.79 42.38% health researches and initiatives all over the country and
National Economic and Development Authority - 2,621,828.00 362,169.26 13.81% encouraging them to pursue future careers in S&T. The first PCHRD-hosted SIP was conceptualized and led
Establishment of PCHRD Health Research and Technology by Mr. Paul Ernest N. de Leon, Chief SRS, PCHRD-RDMD,
Innovation Hubs (HeaRTNovation Hubs): Expanding the TEKI The Council provided a three-week mentorship to students and was pioneered by the Council’s S&T fellows: Dr. Phoebe
in Health Program among Health Institutions through a hybrid setup, with synchronous lectures via Zoom Nicole G. Perez, Dr. Karell Jo Angelique C. Calpito, Dr. Sarah
and complementary facility visits to different implementing Jane A. Jimenez, Dr. Christian Adam L. Espiritu, Dr. Ma. Neda
Food and Drug Association - Development of FDA Clinical 19,800.00 19,800.00 100.00%
agencies. The S&T Fellows facilitated the curation of lectures A. Catalma, Dr. Albert Remus R. Rosana and Dr. Aimee
Trial Regulatory Management Plan
and facility visits with PCHRD’s research partners aiming to Yvonne Criselle L. Aman.
Science Education Institute - Accelerated Science and 26,768,612.11 16,447,186.47 61.44%
maximize the students’ awareness of the research programs
Technology Human Resource Development Program
being done in the Philippines. The SIP is a regular summer
Scholarship Grant
Philippine Health Insurance Corp. - Strengthening the Thrust 30,978,963.31 26,599,178.42 85.86%
for UHC through Data, Information, and Knowledge Exhange
Systems
Total Trust Fund from Other Sources 213,065,658.92 107,919,263.05 50.65%
232 PCHRD ANNUAL REPORT 2022 INSIDE PCHRD 233

FINANCE AND ADMINISTRATIVE DIVISION (FAD)

PCHRD Personnel

As of 31 December 2022, the Council has employed 109 technical staff, 34 administrative and 11 support staff - 2
with doctorate degrees, 16 with master’s degrees, 124 with bachelor degrees, 4 with post high school diploma, and
8 with high school diploma.

OFFICE OF THE EXECUTIVE DIRECTOR (OED)

INSTITUTION DEVELOPMENT DIVISION (IDD)

234 PCHRD ANNUAL REPORT 2022 INSIDE PCHRD 235

RESEARCH AND DEVELOPMENT MANAGEMENT DIVISION (RDMD)

Organizational Structure

RESEARCH INFORMATION, COMMUNICATION

AND UTILIZATION DIVISION (RICUD)
236 PCHRD ANNUAL REPORT 2022 PA R T 4 : C O L L A B O R AT I O N S 237

ANNEXES
 238 PCHRD ANNUAL REPORT 2022 ANNEXES 239

Funded Projects Tuklas Lunas Consortium in the Cordillera: Documentation,

Standardization, and Formulation of Dosage Forms from DIGITAL AND FRONTIER TECHNOLOGIES FOR
Evaluation of the Effectiveness of a UP Manila Covid-19 Trial
Registry in Participant enrollment and validation
Indigenous Plants and Microorganisms with Bioactivities -
Completed Project 1. Potential activity of indigenous and endemic plant
HEALTH
Rapid Assessment of Health Information Systems towards
Process Development of the Dengue Anti-NS1 Rapid
extracts from the Cordillera region against ESKAPE bacteria Diagnostic Test
Pandemic Resiliency and UHC in Two Provinces
PCHRD-funded Studies and Correlation Analyses of Chemical Composition Research Development Proposal for the Liver Research
ARCHER/COVID-19 RabCast: Proof-of-concept for a Forecasting Tool for Rabies
and Bioactivity of three (3) common Philippine Botanial Plants: Program in the Philippines
Relative Risk of Coronavirus Disease-19 (COVID-19) Infection Spread in Davao City Through Combined Genomic and
Antipyretic, Anti-inflammatory, Analgesic Activity of Extracts
and Disease Outcomes with ABO Blood Type among Mathematical Approaches
from Vitex negundo L. and Zingiber officinale Roscoe, and Predictive Value of 24-Hour Bilirubin in Developing
Hospitalized Filipino Patients from Select Tertiary Hospitals in Antimicrobial Activity of Blumea Balsamifera Extract Hyperbilirubinemia among Term Infants in a Multi-Center
Metro Manila, Philippines: An Ambispective Cohort Analysis Immersive Technology Applications in Healthcare
Study in the Philippines
Developing Immersive Technology System for the
Tuklas Lunas Consortium in the Cordillera: Documentation,
Risk Factors, Clinical Characteristics and Transmission of Management of Patients with Dementia and Behavioral and
Standardization, and Formulation of Dosage Forms from
COVID-19 in Non-Pregnant and Pregnant Women in Metro Psychological Symptoms (Phase 1)
Indigenous Plants and Microorganisms with Bioactivities -
Manila, Philippines: A Multicenter Study Developing Immersive Technology Gamification System
Project 6: The formulation & evaluation of capsules containing DOST-funded
for Rehabilitation Management of Pediatric Patients with
herbals with antidiabetic activity ARCHER
’SPECIFieD’: Smart Probes Enabling COVID Identification for Cerebral Palsy and Mobility Limitations (Phase 1)
SOLIDARITY Treatment Trial PLUS: An International
Improved Efficient Diagnosis Chemical and Biological Characterization of Pure and
The UK-Philippines Remote Retinal Evaluation Collaboration Randomized Trial of Additional Treatments for COVID-19
The Immune Response of COVID-19 Peptide-loaded Bioactive Compounds from Kadios (Cajanus cajan) Seeds
in Health: Diabetic Retinopathy (REACH-DR) in Hospitalized Patients Who Are All Receiving the Local
Allogeneic Dendritic Cells and its Topical Formulation Studies Standard of Care

Anti-Coronavirus Therapies to prevent progression of OMIC TECHNOLOGIES FOR HEALTH

DRR-CCA IN HEALTH TUKLAS LUNAS®
COVID-19 (ACT), a randomized trial Epidemiology of Acute and Severe Dengue Infection through
Determining Provincial Health Risk to Climate and Disasters Tuklas Lunas Consortium in the Cordillera: Documentation,
Development of a Cell-Based Immunoassay for Coronavirus the Integrated Analysis of Molecular, Virologic and Clinical
in the Philippines Standardization, and Formulation of Dosage Forms from
Disease 2019 (COVID-19) Serologic Testing Factors
Indigenous Plants and Microorganisms with Bioactivities -
Development of IKSP-based Technologies for Disaster Nanostructured Herbal Extract of Momordica charantia (Bitter
A Cardiovascular Outcome-Moderated Model of the ZooTRIP: Zoonotic transmission of intestinal parasites:
Risk Reduction and Health Emergencies: The Aytas of Mt. Melon/Ampalaya), Allium sativum (Garlic) and Curcuma
Association of COVID-19 Infection and Disease Outcomes implications for control and elimination (Newton Agham
Pinatubo as Models for Climate Change Resilience longa L. (Turmeric) as Antidiabetic Agents
among Hospitalized Patients from Select Tertiary Hospitals Cycle 2)
in Metro Manila, Philippines: A Retrospective Cohort Analysis
FUNCTIONAL FOODS Metabolomics-driven Discovery of Antimicrobial Drug Leads
DIAGNOSTICS
Collection and Archiving of Patient Sera and Plasma for Development of a Turmeric Spray-dried Extract Standardized and Anticancer Screening of Extracts from Marine Sediment-
Isolation and Characterization of Lectins as Ligands for the
Immunochemical Analysis to Detect Antibodies Against for Curcumin and Turmerin for use in Functional Foods Derived Actinomycetes of Iloilo
Development of Lectin-Based Biosensors for the Detection
Infectious Pathogens of Food-Borne Pathogens
Isolation and Characterization of Bioactive Peptides from Discovery and Development of Health Products (DDHP):
Developing and Implementing Testbeds for Low-cost Coconut Fruit (Cocos nucifera L.) Disease-Specific Bioactive Hits from Terrestrial Organisms
Biochemical and Immunologic Characterization and Cross-
Ventilation System Applicable in Tropical Regions for Risk - Project 4. Anti-infective Bioactive Hits Against Methicillin-
reactivity Studies of Allergenic Local Pollen Extracts
Reduction of Infectious Aerosol/Virus Transmission MENTAL HEALTH Resistant Staphylococcus aureus and Klebsiella pneumoniae
Psychosocial interventions used by mental health from Priority Bioactive Extracts
RE-EMERGING AND EMERGING DISEASES
TUKLAS LUNAS professionals for in-patients of tertiary hospitals referred for
The Clinical and Demographic Profile of Dengvaxia Vaccinees Discovery and Development of Health Products (DDHP):
Tuklas Lunas from Endemic/Indigenous Plants in Bicol psychosocial problems
with Suspected Acute Dengue Infection Disease-Specific Bioactive Hits from Terrestrial Organisms
with Pharmacological Activity against Diabetes, Obesity
Patterns of Detection and Treatment of Mental and Behavioral Project 1. Anti-Cancer Drug Leads from Marine Sponges
and Hypertension - Project 1: Screening for anti-diabetic, Seasonal Arboviruses of Aedes albopictus (Diptera: Culicidae)
Disorders among Overseas Filipino Workers (OFWs): Collected Off the Coasts of Mindanao
anti-obesity, and anti-hypertensive activities and toxicity in Highland and Lowland Sites of Cebu city, Philippines
Implications to Psychosocial Support Services Project 5. Potential Anticancer Bioactive Hits from Priority
evaluation of the plant extracts
Bioactive Extracts against Breast Cancer Cell Lines
G.T.A.R.A. (Grip/Grasp Training with Active Range of Motion Project 6. Anti-infective Hits from Priority Bioactive Extracts
Philippine Biorepository Network - Project 3: Development of Understanding the Social Determinants of Mental Well-being
Activities using Guitar): Guitar Lessons for from Indigenous and Endemic Plants of the Cordillera Against
Biobanking Facility for Plant Extracts/Compounds for Drug Restoring Hand Function Among Patients with Unilateral
Acceptability of Telepsychiatry among Overseas Filipino Staphylococcus aureus and Pseudomonas aeruginosa
Discovery Hand Impairment from Chronic Stroke
Workers in Kuwait Project 7. Anti-infective Hits from Priority Bioactive Extracts
from Fungi
 240 PCHRD ANNUAL REPORT 2022 ANNEXES 241

Project 8. Anti-diabetic Bioactive Hits from Priority Bioactive TUKLAS LUNAS® Hydrogel from pig kidneys: Preparation, characterization, and
Extracts from Plants Indigenous to Benguet USA-TLC: Discovery and Development of Health Products pre-clinical assessment for kidney tissue regeneration
Project 9. Anti-Lung Cancer Bioactive Hits from Priority DOST-PCHRD-Funded - USA-TLC Phase II: Early-Stage Development of Antibiotic
Bioactive Extracts ARCHER and Anticancer Leads from Philippine Marine Streptomyces POWer 2: Mobile Biomedical Device Unit to Enhance Access
Project 10. Anti-hyperuricemic bioactive hits from priority Utility of Various Biomarkers in Detecting Cytokine Storm to Upper and Lower extremity devices
plant extracts Syndromes and Predicting Disease Progression and In- ACCELER8: Advancing Antivirals thru Combined SMIDERM: Smart Multifunctional and Indigenous Dressings
Project 11. De-replication with LC-MS Based Metabolomics Hospital Mortality Among Patients with Moderate to Severe Computational Design and Emerging Omics to Leverage sterilized using the Electron beam as novel wound Repair
COVID-19 disease at a Philippine Tertiary Hospital Repurposed and Natural Drugs for SARS-CoV-2 Therapeutics Matrices - Phase I. Biomedical device development and
PHARMAFERN: Development of Health Products from Ferns characterization
- Project 5. Anti-inflammatory Compound/s from Select Assessment of the Gut Microbiome for COVID-19 Diagnosis Pre-Clinical Studies and Scale Up Formulation of Anti-
Ferns in Mindanao and Prognosis Inflammatory PharmaFern Ointments Biomechanical Evaluation of In-House Produced 3D printed
Polyetheretherketone (PEEK) Osteosynthesis Plates for
Potential Anti-Cancer Leads from Plants in Region XII (USM- Evaluation of Plasma Therapy for Retarding Progression and MENTAL HEALTH Simple Mandibular Fractures
TLDC) - Project 1: Screening of plants from Region XII with Preventing Complications in COVID-19 Identifying and Mapping Safe Havens from Stigma and
Potential Anti-Cancer Activity An Experimental Study on the Development of a Liquid Discrimination: Towards Elimination of Hepatits B in the AI-assisted Strategy for 3D-printed Ceramic-Clay and
Medium for On-Site Inactivation of SARS-CoV-2 for RT-PCR Philippines Polymer-Nanoclay Composite Scaffolds Towards Cost-
NUTRITION AND FOOD SAFETY Testing Effective Bone Tissue Repair
Assessment of trans fat content of selected processed food Follow Up Study on Pilot-Testing a Manualized Tele-Synergistic
Seroprevalence of SARS COV2 in Communities in the Aftercare Program for Recovering Drug Dependents among Pediatric Abdominal Wall Defect Closure Assistive Device

OMIC TECHNOLOGIES FOR HEALTH Philippines 17 DOH-DATRCs

Enhanced Capability Building in R&D in GenomicS - OMICS
Establishment of Genomics Consortium and Core Facility in CRADLE S4C Mental Health Status of Youth and Mental Health Resources Investigating the Epidemiology of X-Linked Dystonia-
Mindanao Standardized and Safe Tawa-tawa: Filling in the Final Gaps in the Province of Tarlac Parkinsonism
for a Clinically-proven Nutraceutical Product
Knowledge Management System for Filipino Health Research An Assessment of the Adolescent Telemental Health Services Proteomic Analysis of Philippine SARS-CoV2 Patient
DIAGNOSTICS
Projects (Phase 2) Available in Batangas Plasma by Artificial Intelligence and High-Resolution Mass
Field Integrated Novel Diagnostics for Flaviviruses (FIND-
Spectrometry
Flaviviruses)
Project 1: The ArboChip Project: Molecular Arboviral Detection DIGITAL AND FRONTIER TECHNOLOGIES FOR
Screening for Metabolomic Biomarkers of Diabetic
using Microfluidic Chip Technology
Project 2: Field Integrated Novel Diagnostics for Flaviviruses
New HEALTH
The Development and Implementation Research of the DOH-
Nephropathy in Filipino adult Type 2 Diabetes Mellitus
Patients
Microfluidic Diagnostic Assay PSMID National Antibiotic Guidelines Mobile Application
PCHRD-Funded (NAG App)
Development of an Animal Model for Use in Radiation DIAGNOSTICS
ARCHER
Research and Establishment of the Radiation Research Multicenter Implementation of Orthogeriatrics and the Innovative point-of-care diagnostics and environmental
Wastewater-based Epidemiology of SARS-CoV-2 in the
Center: Core Facility for Radiobiological Research Fracture Liaison Service for Elderly Hip Fractures: An surveillance tools for the elimination of Asian schistosomiasis
City of Manila: Conceptualizing a COVID Risk Assessment
of Community Infection through Surveillance of Sewage Evidence-based Framework for a Sustainable Digital Health
Volatile Organic Compounds Detection in Active Pulmonary Registry Enhanced Digital Image Analysis System for the Assisted
(COVRASS)
Tuberculosis Using Multi-array Metal Oxide Gas Sensor Pathologic Evaluation of Selected Disease Conditions

A Prospective Study on the Accuracy of the CHERISH AI- i-SULAT (Intelligent Stroke Utilization, Learning, Assessment
Development of Paper-based Diagnostic Kit for HIV Drug assisted Diagnosis of COVID-19 Pneumonia (CHERISH2) and Testing): A Development of an Intelligent Quantitative RE-EMERGING AND EMERGING DISEASES
Resistance using Recombinase Polymerase Amplification Software-Based Handwriting Assessment and Testing Metagenomic and genomic surveillance of antimicrobial
DISPO: Design, Development, and Implementation of a System for Early Childhood Handwriting Evaluation resistance in hospital wastewater and computational
RE-EMERGING AND EMERGING DISEASES Natural Language Processing-enabled Virtual Assistant for prediction of efficacy of alternative non-antibiotic therapeutics
Institutional Grant for Invigorating Basic Research on Health Depression and Anxiety among People with Mild COVID-19 Requirements for E-Care System (Alz-e-Med) to Support
Sciences Phase II Patients with Dementia (formerly AI-Based E-Care System to Modelling a Gender Responsive TB Program in the
Antibodies Against COVID-19 among Healthcare workers Support Patients with Dementia (RODE) Community: Validation of Gender Responsiveness Standards
Cataloging Possible Philippine Strains of Zika and African After Boosting (AbACHAB study): Safety, Reactogenicity, and in TB Prevention and Management
Swine Fever Viruses and Coconut Cadang-Cadang Viroid Humoral Immunogenicity of SARS-COV2 booster vaccination RabDash DC: A rabies data analytics dashboard integrating
through Genome Sequencing among Healthcare workers in Makati Medical Center predictive models and genome informatics to support the Characterization of Inflammatory Markers Among Children
rabies control program in Davao City with Different TB Status and On Conversion to Active TB
Assessment of Diagnostic Algorithms and Tools for Multidrug AMPLIFIED: Clinical development of a simplified SARS-
Resistant and Drug Sensitive Tuberculosis in the Philippines CoV-2 genomic point-of-care diagnostic Biomedical Devices Engineering for Health Profiling the Different Vasculitides in the Philippines
Part II (TB-FIT 2)
 242 PCHRD ANNUAL REPORT 2022 ANNEXES 243

DOST-Funded Adaptation and validation of culturally sensitive Mental Health Project 2 Scaling Up and Optimization of Protein Production Development of Cell Isolation Microfluidic Platform Using
Scale for Screening and Diagnosis of NON-SUICIDAL SELF- Project 3 Building Open-Source Instrumentation for Light-Trigger Polymeric Matrix for Cancer Drug Screening
TUKLAS LUNAS
HARM and SUICIDALITY specific for College/University Fermentation and Protein Purification
Securing the Health of the Filipino For The Next Millennium:
Students Project 4 Development of Chemical Tools and Materials for Development of Novel Antiviral Compounds against
The National Institutes of Health National Clinical Trials and
Protein Purification Arthropod-borne Viruses
Translation Center (NIH NCTTC)
Development of a locally relevant and structured educational
Project 3: Unified Data and Safety Monitoring of Clinical Trials
activities and tools for the tertiary level college students, Research and Development Center for Maternal and Child Virology and Vaccine Institute of the Philippines (VIP)
in the Philippines
faculty, staff and guidance counselors Health 3D-HEP-DD: Local adoption of a robust 3D-bioprinted
Project 4: Blended e-Learning Academy of Locally Adapted
HEPatic model for antiviral Drug Discovery research
and Developed Research Modules to Enhance Skills of
DIGITAL AND FRONTIER TECHNOLOGIES FOR Determinants, Management and Prevention Strategies for
Filipino Clinical Investigators to Undertake Investigator-
Childhood Stunting Among Children 0-59 Months Focusing Developing a COVID-19 Oral Vaccine for the Philippines
Initiated Researches" HEALTH
on Maternal and Child Dyad Using the Human Probiotic Yeast, Saccharomyces boulardii
Project 2: Establishment of Pharmaceutical Sciences
ResBac MRSA: Restoring antibiotic activity using
Services for Clinical Research" QARE-HHC: Quicker Analytics for ResponsivE Home Health
Mother and Child Determinants of Pediatric Dengue and Bacteriophages against biofilm-forming Methicillin-Resistant
Project 5: Phase II Clinical Trial of Leucaena leucocephala Care
Development of a Risk Assessment Scoring System for Staphylococcus aureus
Seed Extract Suspension for the Treatment of Ascariasis,
Severe Disease among Filipino Children
Enterobiasis, and Hookworm Infection"
BIOMEDICAL DEVICES ENGINEERING FOR HEALTH SkIn PaTCH Project: Treatment of Skin wound Infection by
Determinants and Risk Assessment Scoring System for multidrug-resistant pathogens using phage therapy cocktail
FUNCTIONAL FOODS Development of a Three-dimensional Bioprinted Human Postpartum Depression Among Filipino Mothers preparations formulated from bacteriophages in hospital
The Cocoa-loca Project: Development of functional food Skin Equivalent for In Vitro Biocompatibility Studies of Topical sewage in in vitro 3D-printed skin infection model"
products and ingredients from cocoa bean shell waste Formulations Identification of genetic variants associated with children’s

Functional Food Program on Philippine Seaweed - Project NeuRoTech: Establishment of the Neurorobotics Technology
growth and development in a Filipino Birth Cohort Ongoing
1. Evaluation of Nutrient Compositions, Potential Health- Center through the DLSU - Institute of Biomedical Engineering PCHRD-Funded
Nutritional status and maternal lifestyle among pregnant
Promoting Properties and Harmful Components in Selected and Health Technologies (IBEHT) women in Samar and Biliran and its Relation to Pregnancy ARCHER
Edible Seaweeds in the Philippines Outcomes during the First 1000 Days: A Prospective Cohort Durability and Extent of Protection of SARS-CoV-2 Antibodies
SELLA Project: EEG-Integrated Wheelchair Power Unit for Study among Patients with COVID-19
NUTRITION AND FOOD SAFETY Patients with Physical Disabilities
Research Center for Rehabilitation/Sports Medicine (Oplan Infant Gut Microbiota and Linear Growth: A Longitudinal CRISPR-based Diagnostics (CRISPR-Dx) for the Detection of
Atletang Pinoy) i-BALIK: Cognitive and Motor Function Rehabilitation using Study of the Eastern Visayas Birth Cohort SARS-CoV-2 and TB
Project 2: The Development of a Local Technology in the Neurofeedback Training System for Stroke Patients
Preparation of Platelet Rich Plasma (PRP) Linking the Metabolome with Genetic Variation, Nutrition, Seroprevalence of Human Adenovirus 5 Neutralizing
Project 3: Development of Software Measuring Patellar SIGLA: Depression Recognition and Analysis from EEG: and Gut Microbiome: An Integrative Omics Approach to Antibodies in an Adult Population from Urban Philippines:
Tendon Displacement in Patellofemoral Pain Syndrome Towards Virtual Reality - based Therapy Program Understand Child Growth and Development among the Implications on Adenoviral Vector-Based SARS-CoV-2
Selected Mother-Infant/Child Dyads of the Eastern Visayas Vaccines
Healthy Aging Program for Pinoy (HAPPY) Senior Citizens: OMIC TECHNOLOGIES FOR HEALTH Birth Cohort
Promoting Quality of Life Among Older Filipinos Through Multi-OMICS Research Program for Health (MORPH) Genetics, Immunological and Neurological Long-term
Food and Nutrition Solutions Monitoring Drug Efficacy through Multi-Omics Research Consequences in Prospective COVID-19 Cohort in Thailand,
DIAGNOSTICS
Project 2: Development and Pilot-Scale Production of Initiative in Alzheimer’s Disease (MEMORI-AD) Japan, Philippines and USA (e-ASIA)
[NICER] Biomaterials for Diagnostics and Therapeutics
Innovative Food Products for Older Male and Female Filipinos Research and Development Center
Project 3: Managing the Nutritional Needs of Older Filipino Molecular Epidemiology of Mycobacterium tuberculosis and Formulation and Standardization of Procaine Hydrochloride
Project 1. Development of a Colorimetric POCT Device for
with Due Attention to Protein Nutrition and Functional Health Human Immunodeficiency Virus among Adult Filipino TB/ – Methylprednisolone Sodium Succinate Powder for Injection
Rotavirus (Viral Gastroenteritis) Detection
(MANO PO) Study HIV Co-infected Patients Project 2. Fecal Lactoferrin, Myeloperoxidase, and Calprotectin
Coronavirus Disease 2019 (COVID-19) Immuno-Genomic
as Differential Markers of Pediatric Acute Gastroenteritis
Determinants of Acquisition, Persistence, and Clearance of Surveillance Program
MENTAL HEALTH Project 3. Synthesis of Biocompatible Nanomaterial
Assessment of pharmacokinetic and pharmacodynamic Oncogenic Cervical Human Papillomavirus Infection in a Conjugated Rabies Peptide Immunogen
Cohort of Women in Rural and Urban Philippines Genomic and Clinical Characterization of an Emerging SARS-
interactions of selected psychobiotic and antidepressant
Establishing the Integrated Protein Research and CoV-2 Variant P.3 in the Philippines
drugs in depression-like rat model RE-EMERGING AND EMERGING DISEASES
Development Center (IPRDC): A Biotechnology Facility for
SAFeV: Survey of cross-reactive Anti-Flavivirus antibodies Establishing an Antibody Neutralization Assay for
Development of a locally relevant and structured educational Health
after Vaccination Characterization and Immunosurveillance of Emerging
activities and tools for the tertiary level college students, Project 1 Enzyme Production: Cloning, Fermentation,
Expression and Characterization at Small Scale SARS-COV-2 Variants of Concern
faculty, staff and guidance counselors
 244 PCHRD ANNUAL REPORT 2022 ANNEXES 245

Treatment of Dengue Without Warning Signs Among Adult Impairment

SARS-Cov-2 Wild Type and Emerging Variants Culture, Filipinos in Cavite: A Randomized, Double-blind, Placebo Development of aptamer based colorimetric and
Isolation, Characterization and Immuno-Challenge Study Controlled Trial Biomedical Devices Engineering for Health electrochemical point of care type diagnostic test for
SiglaVent Design Optimization and Clinical Testing Development of a Cementless Hip Replacement System pulmonary TB and latent TB infection
Discovery and Development of Health Products [DDHP]:
Factors Associated with COVID-19 Infection Among Formulation, Standardization, and Metabolic Profiling of Development of a Magnetic Distal Targeting Device for Affordable near-patient diagnostics to distinguish infectious
Healthcare Workers Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical Intramedullary Nails diseases in the Philippines (AND2ID in Ph) (Newton Agham
Development Cycle 2)"
Developing and Implementing Testbeds for Low-cost Project 2. Standardized Dosage Forms of Biologically Active POWer: Mobile Biomedical Device Unit to Enhance Access
Ventilation System Applicable in Tropical Regions for Risk Extracts Suitable for Use in Preclinical and Clinical Research: to Prosthesis and Orthosis Devices RE-EMERGING AND EMERGING DISEASES
Reduction of Infectious Aerosol/Virus Transmission Top Tier Herbs for Diabetes, Inflammation and Cancer Benchtop and Clinical Validation of an Energized Reusable Development of IoT-Based OL Trap and Community Dengue
Project 3. Standardized Dosage Forms of Biologically Active Laparoscopic Blunt Dissector Early Warning System (C-DEWS) for Cauayan City, Isabela
Determining Safety and Tolerability of a Standardized Extracts Suitable for Use in Pre-clinical and Clinical Research:
Formulation of Andrographis paniculata- A Phase 1 Study Top Tier Herbs for Cancer OMIC TECHNOLOGIES FOR HEALTH Moleculo-epidemiological study of dengue virus among
Project 4. Chemical standardization of top-tier plant extracts The Philippine Virome Database Project livestock and domesticated animals as potential zoonotic
Comparison of the Clinical Course of rt-PCR and Rapid for diabetes, inflammation, and cancer using high performance reservoirs
Antigen Positive Mild COVID-19 Patients Confined in thin layer chromatography The Predict-XDR Project: Predicting Genetic Markers for Pre-
Community Isolation Facilities in Cavite Given Standard Myko-mining and Myko-pharming of Wild Edible and XDR and XDR Tuberculosis (EASIA DOST) Process Development of the Dengue Anti-NS1 Rapid
Treatment Plus Fixed-Dose Combination Capsules of Banaba Poisonous Mushrooms in Luzon Island, Philippines for their Diagnostic Test
and Ginger or Placebo: A Phase 2/3 Randomized, Double- Medicinal Properties (Phase III) Evaluation of the Safety and Feasibility of Intramuscular Autopsy Evaluations of Pathological and Immunological
blind, Placebo Controlled Trial Project 1. Mykopharming of Wild Edible and Poisonous Transplantation of Umbilical cord- derived Mesenchymal Events in Fatal Infections Caused by Arboviruses and
Mushrooms for Their Medicinal Properties Stem Cells for Diabetic Foot Ulceration Emerging Infections
TUKLAS LUNAS®
Synthesis and Derivatization of Disease-specific Bioactive Compounds Active Against Cancer Lines (HCT116, MCF7, Filipino Genomes Research Program The Philippine COPD Profile and Survival Study (CPASS): A
Hits and Lead Compounds (Phase II) - Project 5. Lead A549) from Priority Extracts – Phase II Filipino Forensic Genomics (Phase I) Multicenter, Prospective Cohort, Observational Study
Optimization of Acrylated Cyclopentenone Derivatives with Filipino Genomes: History, Evolution, Origins and Applications
Anti-Inflammatory and Anti-Cancer Activities: Synthesis, FUNCTIONAL FOODS Filipino Genomes Region for to Help Resolve Child Sexual Prospective Urban and Rural Epidemiologic (PURE) Study
Characterization, SAR and ADMETox Studies Moringa oleifera-based Developed (MOD) Nutraceutical Abuse Cases
Product: Nutritional and Metabolome Profiling Regional Prospective Observational Research for Tuberculosis
Microwave-Assisted Synthesis, Characterization and SPEEDIER - Surveillance integrating Phylogenetics and (RePORT) - Community Approach to Control and Halt Drug-
Molecular Docking Studies of Quinoline-4-Carboxylic Acids The Effects of Dietary Fiber and Other Non-digestible Epidemiology for Elimination of Disease: Evaluation of Rabies Resistant TB (COACH DRTB)
and Hydrazide Isosteres with Antitubercular Activity Carbohydrates in a Pre-identified Low Glycemic Index Rice Control in the Philippines
and Stabilized Brown Rice on Gut Microbiota (Newton Agham Cycle 2) DOST-FUNDED
Anti-inflammatory and Anti-diabetic compounds from top- ARCHER
tier bioactive extracts Assessment of Potential Health Benefits and Safety of Wines Using Tuberculosis host-pathogen genetic interactions to Solidarity Vaccine Trial in the Philippines: Randomized Trial of
Produced from Brown, Green, and Red Seaweeds improve diagnostics in the Philippines Candidate Vaccines for COVID-19
Structure Identification of Anti-inflammatory and Anti-Pain (Newton Agham Cycle 2)
Agents from Priority Extracts (Phase 4) NUTRITION AND FOOD SAFETY Technical Battle Against COVId - Project 2. Rational Design
Bacteriophage in Food Safety: Biosensing and Biocontrol of Cellular immunity and resistance to schistosomiasis in the and Structural Modifications of ACE2 Inhibitors from Terrestrial
Discovery and Development of Health Products [DDHP]: Food Pathogen Philippines Plants
Formulation, Standardization, and Metabolic Profiling of (Newton Agham Cycle 2)
Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical A Study Evaluating the Safety and Immunogenicity of Mixing
DIGITAL AND FRONTIER TECHNOLOGIES FOR
Development Different COVID-19 Vaccines and Vaccine Platforms in
Project 1. Standardized dosage forms of biologically active HEALTH
DIAGNOSTICS Filipino Adults
extracts suitable for use in pre-clinical and clinical research: Local Government Unit-mandated eHealth Networked
Responding to the Philippine HIV Epidemic: An HIV Drug
top tier herbs for diabetes and inflammation Services for Universal Health Care (UHC LeHNS)
Resistance Surveillance Library and Development of Vaccine Immune Response and Outcome Monitoring with
Project 7. In vitro Cardiometabolic Activity and Toxicity Molecular Diagnostics for Drug-Resistance Detection Part 3: Epitope Sequences (VIROMES): Application to Philippine
Monitoring of Product Development Samples and Screening The LISA Robot: Logistic Indoor Service Assistant
Development of Rapid Diagnostic for Detecting Lamivudine WHO SOLIDARITY COVID-19 Vaccine Trial
of New Herbals Telepresence Robot
Resistance

POWer App: Mobile Health Application Development for TUKLAS LUNAS®

Efficacy and Safety of Orally Administered Fixed-Dose Enteric Solutions: Development of a Vertical Flow Microarray
Remote Screening & Early Detection of Children with Mobility Synthesis and Derivatization of Disease-specific Bioactive
Combination Capsule of RGA02 + JRA01 + ASB02 in the (VFM) for the Detection of Enteric Viruses
 246 PCHRD ANNUAL REPORT 2022 ANNEXES 247

Hits and Lead Compounds (Phase II) Lunas Program Considerations for Control and Logistics Applied in Mindanao
Project 1. Lead Optimization, In Silico Prediction, Molecular BIOMEDICAL DEVICES ENGINEERING FOR HEALTH Region
Docking and Determination of ADMETox Properties of Small Securing the health of the Filipino for the Next Millennium: Surgical Device Innovation Research and Development Risk Management and Enhanced Survival Analysis Integrated
Molecules as Antidiabetic Drugs The National Institutes of Health Clinical Research (NIH-CRC) (R&D) Infrastructure, Capacity Building and Incubation through Longitudinal Infectious Disease Data and Statistical
Project 2. Molecular Docking and ADME-Tox–guided - Project 1: Science-Based Clinical Research Management Program: Proposal for Establishment of the University of the Epidemiological Model Using Clinical Risk Factors
Synthesis of Azole-Based Anti-Infective Agents Practices Philippines Manila (UPM) College of Medicine (UPCM) –
Project 3. Synthesis of Deguelin, Rotenone, and Small Philippine General Hospital (PGH) Surgical Innovation and Vulnerability Assessment Tool: A Decision Support System for
Molecule Derivatives as Anticancer Agents DRR-CCA IN HEALTH Biotechnology Laboratory (SIBOL) Pre-Emptive Preparedness on Emerging Infections Among
Project 4. Lead Optimization, Molecular Docking and Developing a Geographic Information System to Address Animal Reservoir in Urban Green Spaces
Determination of ADME-Tox Properties of Benzimidazoles Post-Disaster Basic and Health Needs in Temporary Housing iFIX: Design and Fabrication of External Fixator
with Antihypertensive Activity Facilities Operating Room Programmable Electronically Targeted Integrated Wastewater-Based Epidemiology and Data
Project 6. Computer-Aided Drug Design of Natural Products- Active Lighting System (OR PETALS) Analytics for Community Level Pathogen Surveillance and
Based, and Synthetic Antidiabetic, Antifungal, and Anticancer Seasonal Distribution and Allergenicity of Airborne Pollen in Genetic Tracking: Proof-of-Concept
Lead Compounds and Derivatives Ilocos Norte, Philippines iBlood: A Compact Device for Measuring Intraoperative Blood
Loss in Used Surgical Gauze and Laparotomy Packs Early CANcer Detection in the LivEr of Filipinos with Chronic
Bridging Efficacy and Safety: IND-enabling Suite of ADMETox Hepatitis B Using AI-Driven Integration of Clinical and
FUNCTIONAL FOODS
Assays Establishment of the University of the Philippines Manila Genomic Biomarkers (CANDLE Study)
Philippine Program for Diagnostic Biomarkers, Disease
Project 1. Optimization of Physico-Chemical Drug Properties College of Medicine (UPCM) - (PGH) Surgical Innovation and Project 2. AI-driven Integration of Genomic, Ultrasound,
Modeling, and Nutriceutical Product Development (Phil-
Project 2. Cell-based ADMET assays BiOtechnology Laboratory (SIBOL) Serum Biomarkers, and Clinical data for Early Diagnosis of
DIAMOND): Initial Focus on HIV-Related Neurocognitive
Project 3. HPLC and Mass Spectral Studies to Support Various Liver Cancer
and Metabolic Complications - Project 3. Development
ADMET assays Nanotexturing of Stainless Steel 316L by Electrochemical Project 1: Establishing a Clinical and Genomic Profile of
of a Safe Lactic Acid Bacteria (LAB)-based Biofunctional
Project 4. Metabolite Profiling Using Imaging Mass Etching for Biological Implants Filipinos for Early Detection of Liver Cancer
Health-promoting Product as an Adjunct Intervention for the
Spectrometry
Management of HIV-associated
Project 5. Determination of Pharmacokinetic Properties A Proposal to Establish the Philippine Genome Center -
Metabolic Complications" OMIC TECHNOLOGIES FOR HEALTH
Protein, Proteomics and Metabolomics Facility (PPMF) -
Philippine Program for Diagnostic Biomarkers, Disease
DDHP: Marine Component Phase 2 Installation and Operation of the Philippine Genome Center
NUTRITION AND FOOD SAFETY Modeling and Nutraceutical Product Development (Phil-
Project 1. Anti-Pain and Anti-Neurodegeneration Drug -Protein Proteomics, and Metabolomics Facility (PPMF)
Healthy Aging Program for Pinoy (HAPPY) Senior Citizens: DIAMOND): Initial Focus on HIV-related Neurocognitive and
Candidates: Discovery and Development Enhanced Capability Building in R&D in Genomics
Promoting Quality of Life Among Older Filipinos Through Food Metabolic Complications
Project 2. Anti-Infective and Anti-Cancer Drug Candidates
from Marine Microorganisms and Sponges: Discovery and and Nutrition Solutions - Relationship of body composition to Establishment of Genomics Consortium and Core Facility in
the functional capacity and quality of life of older Filipinos in Biomarkers of Immune Dysfunction in HIV – associated
Development Visayas
selected provinces in the Philippines Metabolic and Neurocognitive Complications
Program Management Coordination
Development of HIV Disease Models and in vitro Investigation
Development of Anti-inflammatory Herbal Products from Clinical Proteomics for Cancer Initiative: A Proteomics-Based
of HIV-related Neurocognitive and Metabolic Complications
Iluko Indigenous Plants - Project 3. Formulation Dosage MENTAL HEALTH Discovery of Non-Small Cell Lung Cancer Biomarkers and
Forms from Standardized Non-toxic Bioactive Extracts from Novel Approaches to Treatment of Addiction and Depression Drug Targets in the Philippines Project 2: Sample Processing
Breast Cancer in the Philippines: Gene Expression Profiling of
Indigenous Plants Using Animal Models - Cessation of toluene (Rugby) for Proteomic Analysis and
Breast Cancer Among Filipinos and Development of Breast
addiction in adolescents: Using a rodent model to test novel
Cancer Mammosphere Assay Toward Individualized Cancer
Semi-Purification of Crude Plant Extract: An Essential Step for pharmacological and behavioral treatments for overcoming Functional Characterization and Early Clinical Confirmation
Management
the Production of Pharmaceutical-Grade Ingredients withdrawal and craving of Biomarker Application

Next Generation Sequencing -based expression profiling of

Formulation Quality Control and Stability Studies on Depression, Anxiety, Self-Harm and Suicidal Behavior among Intra-island Zoonotic Transmission of Schistosomiasis in
Breast Cancer among Filipinos and Prediction of Response
Immediate-Release Tablets of Fixed-Dose Combinations of Students in Higher Education Institutions: Sociocultural Leyte, Philippines
to Neoadjuvant Therapy for Locoregionally-Advanced Breast
Cilostazol and Aspirin Determinants, Detection and Intervention towards Social
Cancer in Filipinos
Emotional Learning - A Collaborative Study - Mapping of DIAGNOSTICS
Establishment of the Visayas NMR Laboratory: Enabling the Socio-Cultural Factors and Determinants Associated with Development of Novel Detection Tools for the Integrated
Development of Breast Cancer Mammosphere Assay for
countryside with the power of magnetic resonance for drug Depression, Anxiety, Self-Harm and Suicidality among Surveillance and Monitoring of Helminthic Neglected Tropical
Chemotherapy Screening
discovery and a forward-looking pandemic response Students in Higher Education Institutions Diseases (NTDs) of Mutual Public Health Importance in the
Center for Applied Modeling, Data Analytics, and Philippines and China
Discovery and Development of Health Products: Disease- Development and Effectiveness of Fully Automated
Bioinformatics for Decision-Support Systems in Health
Specific Bioactive Hits from Terrestrial Organisms - Conversational Agents (Chatbots) for Enhancing Public SinoPhil CHARRME: China-Philippines Cooperation for
Predictive Modeling and Viral Phylodynamic Analysis On
Confirmatory and Orthogonal Assays to Eliminate Artefactual Mental Health: From Pilot Study to Randomized Controlled Harnessing and Accelerating Research and Resources on
the Spatial and Temporal Patterns of Disease Outbreaks with
Drug Bioactivities (Phase 3): Continuing Needs of the Tuklas Trial Microvesicles and Exosomes (Development of Exosome
 248 PCHRD ANNUAL REPORT 2022 ANNEXES 249

Probe Chip as Potential Diagnostic for Autoimmune Diseases) Central Philippines (USC-TLDC Phase 2) Bacong, Junelle Rey C. Fernandez, Natasha Andrea Matuloy, Liza S.
Project 3. Chemical Standardization of the Raw Material, Badua, Christian Luke D.C. Gampoy, Eloina Faye S. Realingo, Adeliza Mae L.
Aptamer-Based Multiplex Assay for the Early Detection of Spray-dried Extracts and Dosage Forms from Selected Plants Baldo, Karol Ann T. Girasol, Mark John G. San Valentin, Erin Marie D.
Leptospirosis with Antihyperglycemic Activity Bal-Iyang, Kenworth Bryle A. Grecia, Lordom Reno C. Teruel, Patricia Lyanne A.
Project 5. Formulation Studies of Spray-dried Extracts from Barcena, Allan John R Idolor, Maria Isabel C. Velasquez, Dethalee Gabrielle R.
RE-EMERGING AND EMERGING DISEASES Plants with Antihyperglycemic Activity Bolinas, Dominic Karl M. Lintao, Ryan Cristian V.
Epidemiology, Evolutionary Dynamics and Phylogenetic Buan, Ara Karizza G. Lopez, Ben Anthony A.
ASTHRDP
Analysis of Rabies Virus in the Philippines OMIC TECHNOLOGIES FOR HEALTH Cabungcag, Nica Ona, Kevin Austin L.
Contreras, Patrice Melody C.
Clinical Proteomics for Cancer Initiative: A Proteomics-Based Cadeliña, Joshua Anthony A. Ornos, Eric David B.
Delicana, Reuel C.
Persistence of immunological memory to malaria infection in Discovery of Non-Small Cell Lung Cancer Biomarkers and Cando, Leslie Faye T. Perez, Joy Vanessa D.
Moria, Francis G.
areas of declining transmission Drug Targets in the Philippines Capistrano, Nhel John L. Rojo, Raniv D.
Maynes, Tricia L.
Project 1: Assembly and Archiving of Clinical Samples for Catral, Charlene Divine M. Robles, Joyce Ann H.
Nana, Julie Anne M.
Virology and Vaccine Institute of the Philippines (VIP) Program Proteomic Analysis Ceriales, Jeremy A. Pollo, Brian Andrich La Valle
Pua, Marvin Adrian R.
Project 1. Isolation and purification of Philippine Common Project 3: Proteomic analysis of aberrant protein expression Chua, John Joseph R. Quebral, Elgin Paul B.
Romano, Christopher T.
Viruses with medical importance and pandemic potential for in Non-Small Cell Lung Cancer (NSCLC) Cruz, Joana Marie C. Relador, Ruth Joy L.
Solidum, Andrew James A.
Antigen-Antibody Studies De Galicia, Bryan Paul D. Reyes, Jeremiah V.
Visda, Ann N.
Project 2. Combination Therapy: Lytic Bacteriophages and De Sagon, Scott Dean P. Severino, Mary Elise L.
DOST-DOH-Funded Zimmer, Mary Christine G.
Plant Extracts against Multidrug-Resistant Bacteria Dela Cruz, Ma. Carmela P. Solidum, Jea Giezl N.
ARCHER Escober, Nicole Jazzmine L. Velasco, Adrian Jonathan D.A.
Project 3. Detection of food and water-borne bacterial
Philippine Vaccine Effectiveness Project: A Post-COVID-19 Falcon, Robbi Miguel G. Vidal, Manuel Jr. S.
pathogens using phage-based diagnostics COMPLETED
Vaccination Surveillance Among Filipino Adult Grecia, Mary Nicole I.
Project 4. De Novo Synthesis of Non-Infective Zika Pseudovirus
Guda, Justin V. PCHRD
As Reference for Diagnostics and Vaccines Development
Josol, Vivien Joyce D. COMPLETED Garcia, Clarissa Joy C.
Project 7. Antigenic Peptide VLPs as Potential Candidates for
Covid-19 Vaccine Development Llagas, Julia Patricia B. ASTHRDP

2022 List of New,

Project 8. Development of Antibody Test Kits for COVID-19 Malaluan, Michael Roy V. Sumalde, Angelo Augusto M.
Manalo, Rafael Vincent A. PhD in Health Research,
using Enzyme Immunoassay Tumampo, Cherry Joy F.
Project 1: Establishment of Reference Susceptible Aedes Ongoing, Completed Marco, Kitz Paul D.
Nakpil, Aurora S.
Tan, Joanne Jennifer E.
University of Santo Tomas

Scholars
Mosquito Population" Tantengco, Ourlad Alzeus G.
Opiso, Danna Mae S.
Project 2: Development of Bio - Mosquitocidal from Local Uy, Mary Nadine Alessandra R. NEW
Strain of Bacteria, Bacillus amyloliquefaciens and B. subtilis Paner, Joseph Romeo O.
Project 3: Biological Control of Mosquito Vectors, Aedes spp. Perias, Glenmarie Angelica S.
Ang, Maria Grace A.
Using Natural Organisms Local Scholarship Programs Pineda, Ryan Nikkole B.
Razal, Rozel B.
MS in Molecular Medicine, St. Luke’s Bacorro, Warren R.
Medical Center College of Medicine Bueno, Mary Monica B.
Remucal, Mark Joseph R.
Regional Prospective Observational Research for Tuberculosis MD-PhD in Molecular Medicine, University of William H. Quasha Memorial Fidel, Maria Belinda Cristina C.
Reyes, Michael Sigfrid S.
(RePORT) - Long Term outcomes of Diagnosed Tuberculosis the Philippines Manila
Cases in the Philippines Reyes, Nico Alexander L.
NEW Rocha, Anlene Jane B ONGOING Foreign Graduate
Salvador, Paul Benedic U.
DOST-PCHRD-Funded PCHRD Sanico, Thea Coleen F.
PCHRD Scholarship
Advincula, Jirov A. Antalan, David III G.
ARCHER
Immune Cell Phenotype Characterization of Moderate to Cabrera, Mary Ann F.
Sianoya, Abraham C.
Apostol, K-Anne C. Programs
Teh, Treena Rica D. A.
Severe Coronavirus Disease 2019 (COVID-19) Patients at the Chua, Sean Philippe L. Branzuela, Sandra Mei M.
Vista, Fatima Ericka S. PhD in Molecular Biomedicine,
Philippine General Hospital Collantes, Claire Abigail A. Busog, Aren Maridin M.
Dabban, Romar G. University of Trieste (UNITS)
De Leon, Von Novi O.
and Fondazione Italiana
Technical Battle Against COVID Project 1. Design and Gumaru, Khevin Jade B. ASTHRDP De Guzman, Raphael Joshua C.
Fegato (FIF)
Synthesis of SARS-COV2, ACE2, SARS- COV2:ACE2 Rodriguez, Harley M. Aquino, Inah Marie C. Fariñas, Celeste Aleena V.
Destabilizing Compounds Samante, Fred Lawrence D. Asis, Joannes Luke B. Fernandico, Adrian G.
Cadacio, Jessa Louise C. Garcia, Joshua Roberto B. NEW
Carampel, Ajina C. Jacinto, Patrick Ian J. Garcia, Clarissa Joy C.
ONGOING Cruz, Christian Alfredo K. Limbaga, Lorenzo Gabriel C. Mamerto, Therriz Mae P.
TUKLAS LUNAS®
De Jesus, Federico Cristobal Ii C. Lao, Raphaella G.
Discovery of Cardiometabolic Bioactives from Plants in PCHRD
Dela Rosa, Jared Gabriel L. Magan, Bernard Dominic C.
Alcazar, Renne Margaret U.
Altavas, Patrick D.K.
 250 PCHRD ANNUAL REPORT 2022 ANNEXES 251

ONGOING PhD Health Promotion and Education,

Dimafelix, Paul Raymond S. Pataray, Celia Amour B.
Cabral, Loraine Kay D. UPM Batongmalaki, Roselle F.
MS PH Epidemiology, UERMMMC MS Applied Physics, UST
Laraño, Allen Anthony P. MS Biology, USC
Llido, John Paul S. Galvez, Eleanor J.
Galino, Jeffrey R. Ravelo, Celia R.
Salvoza, Noel C. PhD Health Promotion and Education, Bautista, Felix C. Jr
MS Applied Physics, UST MS Pharmacology, UPM
UPM MS Environmental Science, UPLB
Barbas, Lord Ryan D.
Givero, Rosemarie L. Resurreccion, Michael M.
MS in Tropical Medicine, Lardizaval, Mechelle P. MS PH Epidemiology, UERMMMC
MS Pharmacy, UST MS Clinical Epidemiology, UPM
Faculty of Tropical Medicine PhD Biology, SLU
(FTM), Mahidol University Bernabe, Enrique-Rene G.
Hernandez, Maria Christa A. Reyes, Ruth Irene N.
(SEAMEO TROPMED Malecosio, Serafin O. Jr MS Pharmacy, UST
MS Pharmacy, UST MS Population Studies, UPD
Thailand) PhD Epidemiology, UPM
Botabara, Isagani B.
Javier, Anna Katrina A. Romero, Daryl C.
Maramag, Cherry C. MS Biological Sciences, UST
NEW MS PH Epidemiology, UPM MS PH Epidemiology, UERMMMC
PhD Epidemiology, UPM
Corpuz, Kristal Dale F.
Buhain, Rose Mabell C.
Jacob, Beatriz Aira C. Ladion, Wendell Lou B. Rosario, Mary Rose D.
Miranda, Sheila De Vera MS PH Epidemiology, UPM
MS Biology, MSU-IIT MS Clinical Epidemiology, UPM
PhD Pharmacy, UST
Cabanilla, Carl Vincent D.
Accelerated Science and Technology Lamac, Maria Ruby L. Sayson, Alton John T.
Ongpoy, Romeo C. Jr. MS Chemistry, UPD
Human Resource Development MS PH Epidemiology, UPM MS PH Epidemiology, UERMMMC
PhD Pharmacy, UST
Program (ASTHRDP)
Calibjo, Hartzell M.
Landicho, Shenjira A. Serdiña, Jan Michael B. .
Ramirez, Ma. Anna Rita M. MS PH Epidemiology, UPM
MS PH Epidemiology, UPM MS Applied Physics, UST
PHD PhD Nutrition, UPD
Cauilan, Juan Jhonny M.
Mabeza, Gaiselle F. Solana, Marikka Thaenia V.
Sabinay, Stephen G. MS Pharmacy, UST
ONGOING MS Chemistry, UPD MS Clinical and Family Medicine, UPM
PhD Molecular Biology and
Ang, Mary Jane C. Biotechnology, UPLB Chi, Jean Pauline C.
PhD Medical Microbiology, UPM Macatangay, Sheila H. Soriano, Simonette C.
MS Asian Health Practices, UERMMMC
MS PH Epidemiology, UERMMMC MS PH Epidemiology, UPM
Safra, Sheila Arelli G.
Baco, Fortunata L. PhD Health Promotion and Education, Cu, Richel Erin B.
PhD Epidemiology, UPM Manansala, Teddy S. Tayco, Crimson C.
UPM MS PH Epidemiology, UERMMMC
MS Biochemistry, UPM MS Molecular Biology And Biotechnology, UPD
Bacudio, Ana Maria A. Sucol, Yusuf A. Dagohoy, Marites S.
PhD Medical Microbiology, UPM Manuel, Kaycee G. Teh, Davidson B.
PhD Environmental Science, UPLB MS Pharmacy, UST
MS PH Epidemiology, UERMMMC MS PH Epidemiology, UERMMMC
Bonifacio, Julie Charmain O. Varona, Gracia F. David, April Joy G.
PhD Biology, UPD Marzan, Emil G. Toledo, Franklin U.
PhD Parasitology, UPM MS PH Epidemiology, UERMMMC
MS PH Epidemiology, UERMMMC MS Applied Physics, UST
Cruz, Rogelio S. David, Xenia P.
PhD Biological Science, UST MS Mendoza, Lei Lanna C. Usman, Lourdes Consolacion R.
MS Pharmacology, UPM
MS Medical Microbiology, UST MS Pharmacy, UPM
ONGOING
Cuarto, Ceazar Ryan U. De Jesus, Christopher C.
Ang, Imelda C. Morales, Lyndon DC. Uy, Hilda T.
PhD Chemistry, UST MS Pharmacology, UPM
MS Clinical Epidemiology, UPM MS Biostatistics, UPM MS PH Epidemiology, UERMMMC
Dimaguiba, Justin Rachelle P. De Leon, Rochee M.
Arvesu, Vermont E. Napulan, Roderick M. Valenzuela, Madonna M.
PhD Biology, SLU MS PH Epidemiology, UERMMMC
MS Pharmacology, UPM MS Biostatistics, UPM MS Biostatistics, UPM
Encarnacion, Richard I. Del Rosario, Glenn Sandee C.
Balce, Roderick D. Oco-Panganiban, Maria Michelle Joy P. William, Karmille-Allyson D.
PhD Molecular Biology and MS PH Medical Microbiology, UPM
MS Microbiology, UST MS Family Medicine, UPM MS PH Epidemiology, UERMMMC
Biotechnology, UPD

Banzon, Joseph Joy G. Dicdican, Isabel D.

Gregorio, Ernesto Ramos Jr. Pagarigan, Geraldine Yap, Kristine Jeanne A.
MS Medical Technology, UST MS Chemistry, MSU-IIT
MS Tropical Medicine, UPM MS Medical Microbiology, UPM
 252 PCHRD ANNUAL REPORT 2022 ANNEXES 253

Balik Scientist TV/Radio Interview

List of accredited REGION VI
University of St. La Salle Research Ethics Committee

Awardees Teleradyo interview with Katipunan Channel (https://www. Research Ethics November 10, 2022

Dr. Myra O. Villareal (ST), Bicol University

facebook.com/partidokdp/): March 9, 2022
Dr. Salvador Caoili– as Resource Speaker Committees (RECs) in REGION VI

Dr. Aloysius R. Domingo (ST), UP-NIH

Dr. Ike C. de la Peña (ST), Manila Adventist College
Topic: Host Institution experience and programs/projects
with Balik Scientist
2022 Western Visayas Health Research and Development
Consortium Research Ethics Committee
Link: https://www.facebook.com/partidokdp/ November 14, 2022
Dr. Thaddeus M. Carvajal (LT), DLSU Manila
Dr. Rose Constantino (ST), Cebu Normal University (CNU) videos/314337587348052/ LEVEL 1
NCR REGION VI-A
Dr. Gerard Dumancas (ST), University of San Agustin
Teleradyo interview with EAT Konek (DZEC 1062 KHZ Radyo Mary Johnston Hospital Research Ethics Committee University Of The Philippines Los Banos - Ethics Review
Dr. Isaiah Paolo Lee (ST), National Institute of Molecular
Agila): March 20, 2022 February 15, 2022 Committee (ERC)
Biology and Biotechnology (NIMBB), University of the
Dr. Gerard Bryan Gonzales – as Resource Speaker September, 22, 2022
Philippines Diliman
Dr. June Bryan De la Pena (ST), Eastern Visayas Health Topic: Balik Scientist Program and project related to nutrition NCR
Ospital ng Makati Research Ethics Board REGION X
Research and Development Consortium (EVHRDC)
ABS-CBN Interview for TV Patrol feature on Alam Nyo Ba? June 8, 2022 Northern Mindanao Medical Center Research Ethics Board
Dr. Heidie Frisco-Cabanos (ST), University of the Philippines
Segment June 29, 2022
Manila, College of Medicine, Department of Biochemistry and
Molecular Biology (UPM-CM-DBMB) Dr. Lourdes Nadala, Dr. Christina Lora Leyson and Dr. Myra NCR
Dr. Jennifer Yang (ST), Department of Rehabilitation Medicine, Hosmillo – University of the Philippines - College of Home Economics LEVEL 2
UP College of Medicine as Resource Speakers Research Ethics Committee NCR
Pre-recorded interview: March 9 and 14, 2022 July 13, 2022 Trinity University of Asia - Institutional Ethics Review

BSP coordinated and

Topic: Women of VIP Balik Scientists in celebration of
Committee (IERC)
Women’s Month Celebration NCR January 5, 2022
assisted activities in CNN Interview
University of Santo Tomas Graduate School - Research Ethics
Committee
2022 Dr. Lourdes Nadala, and Dr. Myra Hosmillo – as Resource
Speakers
July 31, 2022
NCR
University of Santo Tomas- College of Rehabilitation
Sciences Ethics Review Committee
DOSTv Report/ DOST ExperTalk Online Pre-recorded interview: March 14, 2022 NCR June 8, 2022
Dr. Teodoro Fajardo – as Resource Speaker Topic: Women of VIP Balik Scientists in celebration of Rizal Medical Center Institutional Review Board
Pre-recorded interview: January 24, 2022 (Monday), 02:00 Women’s Month Celebration December 1, 2022 REGION 1
PM PST/ 06:00 AM UK Time Region 1 Health Research and Development Consortium
Segment airing: January 26, 2022 (Wednesday) NCR March 28, 2022
Regional Activities
Tondo Medical Center Research Ethics Committee
Dr. Fidela L. Moreno – as Resource Speaker December 28, 2022 REGION I
Science for Change Program Regional Visit and interview of
Pre-recorded interview: February 1, 2022 (Tuesday), 10:00 AM DOH Drug Treatment and Rehabilitation Center Dagupan
Host Institution
PST REGION I July 7, 2022
Ms. Jean Ragub - as Resource Speaker
Segment airing: February 2, 2022 (Wednesday) Ilocos Training and Regional Medical Center Research Ethics
Pre-recorded interview: March 21, 2022
Committee (REC) REGION II
Dr. Ike de la Peña as featured on DOST Report Episode 131 January 10, 2022 Cagayan Valley Medical Center Research Ethics Review
S4CP/BSP Monitoring Activities and Summit in Western
Pre-recorded interview: Nov 2, 2022 01:30 PM Asia/Manila Committee
Visayas (May 5-6, 2022)
Segment airing: Nov. 4, 2022 REGION I September 5, 2022
The BSP PCHRD facilitated the interviews and video shoot
Link: https://fb.watch/hdPPQBK1Aj/ Lorma College Research Ethics Committee
for the regional visit. The materials gathered will be used in
May 11, 2022 REGION III
the Balik Scientist Achievement Award, and institutional video
Dr. Isaiah Paolo Lee as featured on DOST Report Episode 132 Holy Angel University Institutional Review Board
of the Program.
Pre-recorded interview: Nov 9, 2022 01:30 PM REGION VI June 10, 2022
The following key persons from the University of San Agustin
Segment airing: Nov. 11, 2022 Central Philippine University
(USA) were interviewed:
Link: https://fb.watch/hdPIswN3zx/ October 11, 2022 REGION III
Dr. Julius Adam Lopez - ongoing Medium-Term awardee
(2021) Dr. Paulino J. Garcia Memorial Research and Medical Center
REGION VI July 28, 2022
Fr. Frederick C. Comendador - USA President, Host Institution
University of the Philippines Visayas Research Ethics Board REGION VI
Focal person
October 24, 2022 Western Visayas Medical Center Ethics Review Committee
 254 PCHRD ANNUAL REPORT 2022 ANNEXES 255

June 14, 2022 Committee in Chicken and Pork Glutamate-induced Neurological Aberrations in Male CD-1
REGION VII April 12, 2022 Mice
University of San Carlos Research Ethics Committee LIMPIO: Lessening Infestation of Microbes and Parasites
September 5, 2022 REGION VII through Interventions in Open-field farms in Marilog District, Probiotic Potential of Lactic Acid Bacteria from Fermented
REGION XI Vicente Sotto Memorial Medical Center Research Ethics Davao City Market-Scrapped Fruit and Vegetable Materials and its
Davao De Oro State College Research Ethics Review Committee Antagonistic Activity against Selected Food and Water
Committee July 1, 2022 Water Quality Assessment and Evaluation of Human Health Borne Pathogens
December 15, 2022 Risk in Selected Rivers of Lanao del Sur, Philippines
REGION XI Green Synthesis of Metal Oxide Cellulose Nanocrystals
Metro Davao Medical and Research Center, Inc. - Anda Physical Activity of the Elderly in the 4th District of Leyte (MO-CNC) for Health-related Applications Phase 1
Riverview Medical Center, Inc. Cluster Research Ethics amidst COVID-19 Pandemic
LEVEL 3 Review Committee Screening for New Antimicrobials and Antioxidants from
NCR July 23, 2022 Predictors of Clinical Outcomes of COVID-19 Confirmed Penicillium and Talaromyces Species Isolated from Various
University of the Philippines Manila Research Ethics Board Adult Patients Hospitalized in Eastern Visayas Medical Sources in Bicol Region, Philippines
March 7, 2022 REGION XI Center
Department Of Health XI Cluster Ethics Review Committee - Predictive Risk Mapping of Leptospirosis in Benguet using
NCR Research Ethics Committee (REC) Ongoing Environmental and Socioeconomic Data
Jose R. Reyes Memorial Medical Center Institutional Review August 2, 2022 Assessment of Organizational Cultures of Health Workforce Bacterial Antibiotic Resistance Pollution in Balili River
Board
in DOH- Retained Hospitals, Region 1
Regional Research
April 11, 2022
Hearing Screening Protocol Among Pupils With Special Associations of Physical Activity, Screen time and Sleep
with Health and Developmental Outcomes among Filipino
Fund (RRF)
Healthcare Needs in Ilocos Norte
NCR Preschool Children
St. Cabrini Medical Center-Asian Eye Institute Ethics Review
Serologic SARS-CoV-2 Antibody Level and Factors
Committee
Affecting Its Production After COVID-19 Vaccination Among Effectiveness of Ultrasound Guided Interfascial
June 1, 2022 Completed
Employees of Mariano Marcos Memorial Hospital and Hydrodissection with the use of Saline Anesthetic Solution
Quantification of Antibiotic Resistance Genes of
Medical Center for Myofascial Pain Syndrome of the Upper Trapezius: A
NCR Enterobacteriaceae from an Organic Farm and their
Single Blind Randomized Control Trial
Far Eastern University - Dr. Nicanor Reyes Medical Products in Benguet
Prevalence and Influencing Risk Factors of Health
Foundation Institutional Ethics Review Committee
Conditions Among Tobacco Farmers in Ilocos Norte FightBac: Virtual Screening for Quorum Quenchers from
September 25, 2022 In vitro and In Vivo Anti-hypercholesterolemic activity of
Natural Product Database and their Synergistic Antibacterial
Alocasia macrorrhiza (Araceae) and its Food Products
Bioassay-Guided Isolation of Antibacterial Compounds Study
NCR
Ultrastructural Characterization of Snail-associated Digenic from Mikania cordota Flower against Methicillin-Resistant
Lung Center of the Philippines - Institutional Ethics Review
Staphylococcus aureus (MRSA) Clinical Isolate Maternal and Child Health Service Utilization in Selected
Board Parasites in Rice fields Surrounding Lake Mainit, Philippines:
Municipalities in Iloilo Province Before and During the
October 3, 2022 Implications for Transmission and Control of Schistosomiasis
Comprehensive Evaluation of the Molluscicidal Activity of COVID-19 epidemic, Western Visayas, Philippines: A
and Snail Transmitted Diseases: Phase I (Collection and
Euphorbia splendens Latex against Oncomelania quadrasi Retrospective Cohort Study
NCR Isolation of Trematodes)
University of the East Ramon Magsaysay Memorial Medical Microplastic and Its Public Health Implications in Select Key
Factors Associated with Acceptability of Mass Drug Assessment of Infection Prevention and Control in Different
Center, Inc. Research Institute for Health Sciences Ethics
Levels of Health Care Facility in Cagayan Valley (Region II) Tourist Destinations in Cebu, Philippines
Review Committee Administration for Morbidity Control of Schistosomiasis
October 5, 2022
Extraction, Characterization and Bioactivity Evaluation of the Nutritional Composition of Halymenia durvillei and its
Newly-approved Potential Use as a Food Ingredient
Essential Oils of Fruit Wastes
NCR Epidemiology of Zoonotic Toxoplasma gondii Infection
Peregrine Eye and Laser Institute Institutional Review Board Among Household Cats in Region X
Development and Evaluation of Herbal Skincare Products Developing a Tool to Measure the Decision-Making
October 24, 2022 Exploring Antimicrobial Medicinal Plants used by Indigenous
infused with KaPaMa Plant Extracts for Infections Processes in Sex Practices among Men-who-have-sex-with-
Natives in Two Mountain Ecosystems of Bukidnon, men anchored on Protection Motivation Theory (PMT)
REGION IV-A Philippines (EXAMINE Bukidnon)
Detection of Staphylococcus aureus and its Methicillin-
Batangas Medical Center Research Ethics Review
Resistant Strain: A Basis for a Proposed Effective Infection Molecular Detection of Selected Tick-borne Pathogens in
Committee The Lived Experiences of COVID-19 Survivors in Northern
Prevention and Control Program of Selected Government dogs, dog owners and veterinary clinicians/technicians in
April 12, 2022 Mindanao
Hospitals in Pampanga Cebu, Philippines

REGION VII Development of a Cost Effective HPLC-FLD Analytical

The Anti-oxidant and Histo-protective Potentials of Balakat Clinico-Demographic Profile of Reported Child Injury Cases
Cebu Doctors’ University Hospital Research Ethics Method for the Quantification of Residual Fluoroquinolones
Tree (Ziziphus talanai (Blanco) Merr.) against Monosodium in Selected Rural Municipalities in N. Samar (2014 - 2016)
 256 PCHRD ANNUAL REPORT 2022 ANNEXES 257

January 1 "5,901 participants of WHO Solidarity National News, Manila Bulletin"

Chips Consumption as a Risk factor for UTI Among School Development of a Cost Effective HPLC-FLD Analytical DWIZ 882 AM Trial already received first dose of
Children in Tacloban City Method for the Quantification of Residual Fluoroquinolones https://www.dwiz882am.com/index. COVID-19 vaccines -- DOST "PH real-world study on 'effectiveness'
in Chicken and Pork php/dost-makikipagtulungan-sa- January 7 of COVID-19 vaccines to end by June
Child Injury Among Patients Seen in All District Hospitals of mga-coconut-processors-para- 24 Pilipinas 2022 -- DOST
Leyte Health Risk Management Practices in Flood-Prone Public maaprubahan-ang-vco-kontra- https://www.24pilipinas.com/ January 8
Elementary Schools in Caraga Region covid-19/" lifestyle/5901-participants-of-who- Manila Bulletin
Prevalence and Nature of Antibiotic Residues in Pork and solidarity-trial-already-received- https://mb.com.ph/2022/01/08/ph-
Poultry Meats Collected from Public Wet Markets and "Chairperson, Vaccine Expert Panel Dr. first-dose-of-covid-19-vaccines- real-world-study-on-effectiveness-of-
Private Meat Shops in Leyte Media Mileage Nina Gloriani
January 3
dost/299297-news" covid-19-vaccines-to-end-by-june-
2022-dost/"
TAMBALAN: An Ethno-botanical Study Traditional Healing DOST, stakeholders seek FDA approval of VCO vs COVID Public Briefing Laging Handa "5,901 nakiisa sa WHO Solidarity Trial
Practices and Herbal Medicines in Sitio Pena 2, Calbayog January 1 Philippines, PTV 4" naturukan na ng 1st dose COVID vax "92 plant species to be included in PH
City News, Philippine Star — DOST study on allergenic airborne pollen in
"Panayam kay Dr. Nina Gloriani, DOST January 7 Ilocos Norte
Synergistic Anti-Urolithiatic Activity Of Potassium Citrate and "DOST, stakeholders seek FDA approval of VCO vs Vaccine Development Expert Panel, Remate Online January 8
Blumea balsifera Extract On Calcium Oxalate Stones COVID-19 Head https://www.remate.ph/5901-nakiisa- Manila Bulletin
January 1 January 3 sa-who-solidarity-trial-naturukan-na- https://mb.com.ph/2022/01/08/92-
Determination of chlortetracycline residue in chicken (Gallus Philippine Star ACS Balita, DZRH TV" ng-1st-dose-covid-vax-dost/" plant-species-to-be-included-in-ph-
gallus domesticus) meat products from public markets of https://www.philstar.com/headlines/2022/01/01/2151215/ study-on-allergenic-airborne-pollen-in-
Zamboanga City dost-stakeholders-seek-fda-approval-vco-vs-covid-19" "Panayam kay Dr. Nina Gloriani, DOST "5,901 participants of WHO Solidarity ilocos-norte/"
Vaccine Development Expert Panel, Trial already received first dose of
Mathematical Models for Predictions and Preparedness "DOST, stakeholders seek FDA approval of VCO vs Head COVID-19 vaccines -- DOST "332 nakiisa sa Ph ‘mix and match’ trial;
(MMOPREPARE) COVID-19 January 3 January 7 first dose na Sinovac vax naiturok na
January 1 ACS Balita, DZRH AM" Manila Bulletin January 8
Perceived Effectiveness of Community-based Drug MSN News https://mb.com.ph/2022/01/07/5901- Remate Online
Rehabilitation Program in Valencia City, Bukidnon: https://www.msn.com/en-ph/news/national/dost- "Panayam kay Dr. Nina Gloriani , DOST participants-of-who-solidarity-trial- https://www.remate.ph/332-nakiisa-
Perspectives and Experiences of Drug Responders and stakeholders-seek-fda-approval-of-vco-vs-covid-19/ar- Vaccine Expert Panel Chairperson already-received-first-dose-of-covid- sa-ph-mix-and-match-trial-first-dose-
other Stakeholders AASjGs5" January 3 19-vaccines-dost/" na-sinovac-vax-naiturok-na/"
Round Up, DZBB"
Evaluation of the Antibacterial Properties of Cocoa "DOST, stakeholders seek FDA approval of VCO vs "332 participants of PH 'mix and match' "DOST mailalabas na ang resulta ng
(Theobroma cacao) Husk Extracts Pandemic "Panayam kay Dr. Nina Gloriani, DOST, trial get first dose of Sinovac vaccine isinagawang clinical trial ng ivermectin
January 1 Vaccine Expert Panel January 7 January 8
Plant mediated synthesis of silver nanoparticles using Trending PH January 3 Manila Bulletin Unang Radyo sa Unang Balita, DZXL"
mangosteen pericarp and their antimicrobial potential http://trendingph.net/dost-stakeholders-seek-fda-approval- Agenda ng Bayan, DZRB" https://mb.com.ph/2022/01/07/332-
of-vco-vs-covid-19/" participants-of-ph-mix-and-match-trial- "Inaasahan mailalabas na ngayong
Evaluation of Philippine Mango pectin as tablet binder for "DOST chief urges use of radiation get-first-dose-of-sinovac-vaccine/" buwan ng DOST ang mga clearance
formulated Sambong tablet "DOST, stakeholders seek FDA approval of VCO vs monitoring facility ng 8 buwan ivermectin clinical trial
COVID-19 January 6 "Clearances for PH Ivermectin clinical January 8
Carotenoid Extraction and Characterization from Davao January 1 Manila News trial expected to be released within RMN News Nationwide: The Sound of
Carrots as a Potential Pharmaceutical Colorant Atin Ito News https://www.manilanews.net// January --DOST exec the Nation (7 AM), DZXL"
http://www.atinitonews.com/2021/12/dost-stakeholders- news/272114662/dost-chief-urges-use- January 7
Bacteriocin from Fermented Durian Rinds to Prevent Food seek-fda-approval-of-vco-vs-covid-19/" of-radiation-monitoring-facility" Manila Bulletin "332 indibidwal lumahok sa
Safety Issues https://mb.com.ph/2022/01/07/ isinagawang mix & match trial ng
Screening and Quantification of Antimicrobial Residues in "DOST, nakikipag-ugnayan sa asosasyson ng mga coconut "DOST chief urges use of radiation clearances-for-ph-ivermectin-clinical- Covid-19 vaccine sa bansa
Chicken Meat and Tissues in Davao City using Microbial procesors sa bansa para maaprubahan ng FDA ang VCO monitoring facility trial-expected-to-be-released-within- January 8
Inhibition Assay and Enzyme-Linked Immunosorbent Assay para sa mild Covid-19 cases January 6 january-dost-exec/" Network Balita, DZRB"
(ELISA) January 1 Manila News
Network Balita, DZRB" https://www.manilanews.net/ "Clearances for PH ivermectin clinical "DOST-funded COVID vaccine mix-
COURAGE: The Correlation between CYP3A5 Gene news/272114662/dost-chief-urges-use- trial expected to be released this month and-match study underway
Polymorphisms and Tacrolimus Concentration-to-Dose "DOST makikipagtulungan sa mga coconut processors para of-radiation-monitoring-facility" - DOST January 10
Ratio among Kidney Transplant Recipients in Mindanao maaprubahan ang VCO kontra COVID-19 January 8 News, Philippine Star"
 258 PCHRD ANNUAL REPORT 2022 ANNEXES 259

"DOST-funded COVID-19 vaccine mix- "Panayam kay Dr. Nina Gloriani, DOST COVID-19 Panel "DOST: Right lagundi dosage can Manila Bulletin
and-match study underway Vaccine Development Expert Panel, January 11 January 12 relieve COVID-19 symptoms https://mb.com.ph/2022/01/15/5901-
January 10 Head The Big Story, One News" Balitalakayan, Net 25" January 15 participants-of-who-solidarity-trials-
Philippine Star January 10 PTV News get-first-dose-of-covid-19-jabs/"
https://www.philstar.com/ ACS Balita, DZRH TV" "Adult Infectious Disease Expert SLH "Panayam kay Dr. Nina Gloriani , DOST- https://ptvnews.ph/dost-right-
headlines/2022/01/10/2152809/dost- and Vaccine Expert Panel, DOST, Dr. VEP Chairperson lagundi-dosage-can-relieve-covid-19- "Lagundi mabisa sa COVID 'pag
funded-covid-19-vaccine-mix-and- "Vaccine expert; Variants posibleng Rontgene Solante January 12 symptoms/" tamang dosage - DOST
match-study-underway" madagdagan pa kung patuloy ang January 11 Playback, DZMM" January 15
pagdami ng mga nahahawa Rise and Shine Pilipinas, PTV 4" "Right lagundi dosage can relieve Abante
"DOST-funded COVID-19 vaccine mix- January 10 "DOST Vaccine Expert Panel - Covid-19 symptoms: DOST https://www.abante.com.ph/lagundi-
and-match study underway Headline Pilipinas, DZMM Teleradyo" "Vaccine Expert Panel Dr. Gloriani Chairperson Dr. Nina Gloriani January 15 mabisa-sa-covid-pag-tamang-dosage-
January 10 nagpaalala sa publiko kaugnay sa January 12 Manila News dost/"
Philippine Star "DOST Vaccine Expert Panel - posibleng pagdami ng variant ng Sakto, DZMM" https://www.manilanews.net/
https://www.philstar.com/ Chairperson Dr. Niña Gloriani Covid-19 sa bansa news/272175962/right-lagundi- "Right lagundi dosage can relieve
headlines/2022/01/10/2152809/dost- January 10 January 11 "Panayam kay Dr. Nina Gloriani, Head dosage-can-relieve-covid-19- Covid-19 symptoms: DOST
funded-covid-19-vaccine-mix-and- On The Spot, DZMM Teleradyo" Balitang Todo Lakas, DWIZ" of Vaccine Panel, DOST symptoms-dost" January 15
match-study-underway" January 14 Manila News
"DOST; Pag-aaral para sa mix and "Vaccine Expert Panel Dr. Gloriani Kada Umaga, Net 25" "Right lagundi dosage can relieve http://manilanews.ph/right-lagundi-
"DOST-funded COVID-19 vaccine mix- match ng mga bakuna vs Covid nagpaalala sa publiko kaugnay sa Covid-19 symptoms: DOST dosage-can-relieve-covid-19-
and-match study underway makukumpleto na posibleng pagdami ng variant ng "Panayam kay Dr. Jaime Montoya , January 15 symptoms-dost/"
January 10 January 10 Covid-19 sa bansa DOST-PCHRD Director Manila News
Philippine Star Teleradyo Balita, DZMM Teleradyo" January 11 January 14 https://www.manilanews.net// "Correct lagundi dosage seen to relieve
https://www.philstar.com/ IZ Sa Alas Sais, DWIZ" Dobol Weng Sa Dobol B, DZBB" news/272175962/right-lagundi- COVID-19 symptoms -- DOST
headlines/2022/01/10/2152809/dost- "Vaccine expert; Variants posibleng dosage-can-relieve-covid-19- January 16
funded-covid-19-vaccine-mix-and- madagdagan pa kung patuloy ang "Vaccine Expert Panel Dr. Gloriani "DOST-11 offers as much as P1-M for symptoms-dost" Manila Bulletin
match-study-underway" pagdami ng mga nahahawa nagpaalala sa publiko kaugnay sa health-related proposals https://mb.com.ph/2022/01/16/
January 10 posibleng pagdami ng variant ng January 14 "Right lagundi dosage can relieve correct-lagundi-dosage-seen-to-
"DOST-funded COVID-19 vaccine mix- Headline Pilipinas, DZMM" Covid-19 sa bansa Philippine News Agency Covid-19 symptoms: DOST relieve-covid-19-symptoms-dost/"
and-match study underway January 11 https://www.pna.gov.ph/ January 15
January 10 "Panayam kay Dr. Nina Gloriani, DOST IZ Balita Nationwide Umagang Edition, articles/1165457" Philippine News Agency "Lagundi mabisa sa coronavirus
Philippine Star Vaccine Development Expert Panel, DWIZ" https://www.pna.gov.ph/ January 16
https://www.philstar.com/ Head "P1-M fund grant to boost health R&D articles/1165495" News, Abante"
headlines/2022/01/10/2152809/dost- January 10 "Asian Hospital to hold 5th Clinical in Davao
funded-covid-19-vaccine-mix-and- ACS Balita, DZRH AM" Innovation Summit January 14 "DOST eyes VCO nasal inhaler, mouth "‘Lagundi can relieve COVID
match-study-underway" January 12 Billboard, Sun Star Davao" wash vs COVID-19 symptoms’‘
"DOST Vaccine Expert Panel - Business Mirror January 15 January 16
"DOST-funded Pandemic vaccine mix- Chairperson Dr. Niña Gloriani https://businessmirror.com. "Clinical trial sa VCO sa mga Manila Bulletin Front Page, Tempo"
and-match study underway January 10 ph/2022/01/12/asian-hospital-to-hold- pasyenteng may covid-19, tagumpay https://mb.com.ph/2022/01/15/dost-
January 10 On The Spot, DZMM" 5th-clinical-innovation-summit/" January 15 eyes-vco-nasal-inhaler-mouth-wash- "DoST offers P1M for health-related
Trending PH Headline Balita, DZBB" vs-covid-19/" proposals
http://trendingph.net/dost-funded- "DOST; Pag-aaral para sa mix and "Panayam kay Dr. Nina Gloriani , DOST- January 16
covid-19-vaccine-mix-and-match- match ng mga bakuna vs Covid VEP Chairperson "Department of Science &Technology "5,901 participants of WHO solidarity Opinion News, Peoples Journal"
study-underway/" makukumpleto na January 12 Dr. Jaime Montoya trials get first dose of COVID-19 jabs
January 10 Playback, DZMM Teleradyo" January 15 January 15 "Right lagundi dosage can relieve
"DOST-funded COVID-19 vaccine mix- Teleradyo Balita, DZMM" Bigtime Balita, DZBB" Manila Bulletin Covid-19 symptoms: DOST
and-match study underway "DOST Vaccine Expert Panel - https://mb.com.ph/2022/01/15/5901- January 16
January 10 "DOST susuriin 92 uri ng halaman Chairperson Dr. Nina Gloriani "Rekumendasyon para sa paggamit participants-of-who-solidarity-trials- Philippine Times
Atin Ito News January 11 January 12 ng VCO para sa mga pasyenteng may get-first-dose-of-covid-19-jabs/" https://www.philippinetimes.com/
http://www.atinitonews.com/2022/01/ Editorial, Abante Tonite" Sakto, DZMM Teleradyo" covid-19, inihahanda na news/272175962/right-lagundi-
dost-funded-covid-19-vaccine-mix- January 15 "5,901 participants of WHO solidarity dosage-can-relieve-covid-19-
and-match-study-underway/" "Executive Director, DOST-PCHRD Dr. "Panayam kay Dr. Nina Gloriani, Head Super Balita sa Tanghali Nationwide, trials get first dose of COVID-19 jabs symptoms-dost"
Jaime Montoya- PH at 'critical risk' for DOST Vaccine Development Expert DZBB" January 15
 260 PCHRD ANNUAL REPORT 2022 ANNEXES 261

"Lagundi can help vs Covid January 17 covid-19-patients" recommend-lagundi-for-covid-19- "3 RHUs In Davao Oriental Receive kinalaman sa Covid-19, ating klaruhin
January 16 News, Philippine Star" patients/" RxBox And Training From DOST-XI January 18
Page Three, Daily Tribune" "UP researchers recommend lagundi January 17 Rise and Shine Pilipinas, PTV 4"
"VCO NASAL INHALER, MOUTH for COVID-19 patients "UP researchers recommend lagundi The Mindanao Life
"VCO nasal inhaler, mouth wash vs WASH VS COVID January 17 for COVID-19 patients http://themindanaolife.com/3-rhus- "Panayam kay Dr. Cecilia Maramba-
COVID pinag-aaralan ng DOST January 17 Philippine Star January 17 in-davao-oriental-receive-rxbox-and- Lazarte , Research Methods Expert
January 16 News, Bagong Sagad" https://www.philstar.com/ Philippine Star training-from-dost-xi/" January 18
Remate Online headlines/2022/01/17/2154343/ https://www.philstar.com/ Playback, DZMM Teleradyo"
https://www.remate.ph/vco-nasal- "UP researchers recommend lagundi researchers-recommend-lagundi- headlines/2022/01/17/2154343/ "Posibleng mawala ang mild
inhaler-mouth-wash-vs-covid-pinag- for COVID-19 patients covid-19-patients" researchers-recommend-lagundi- symptoms ng Covid-19 gamit ang "Research Methods Expert Clinical
aaralan-ng-dost/" January 17 covid-19-patients" tamang dosage ng lagundi Trial - Dr. Cecilia Maramba-Lazarte
Philippine Star "UP researchers recommend lagundi January 17 January 18
"Dengvaxia vilifier Acosta cries https://www.philstar.com/ for COVID-19 patients "3 RHUs In Davao Oriental Receive ACS Balita, DZRH TV" Kabayan, DZMM Teleradyo"
'discrimination' against anti-vaxxers headlines/2022/01/17/2154343/ January 17 RxBox And Training From DOST-XI
amid COVID-19 surge researchers-recommend-lagundi- Philippine Star January 17 "DOST Sec. Dela Pena, hinimok ang "Panayam kay Dr. Cecilia Maramba-
January 16 covid-19-patients" https://www.philstar.com/ The Luzon Daily mga nagpositbo sa Covid-19 na Lazarte , Research Methods Expert
Abogado headlines/2022/01/17/2154343/ http://theluzondaily.com/3-rhus-in- sundin ang guidelines sa pag-inom ng January 18
https://abogado.com.ph/dengvaxia- "UP researchers recommend lagundi researchers-recommend-lagundi- davao-oriental-receive-rxbox-and- lagundi Playback, DZMM"
vilifier-acosta-cries-discrimination- for COVID-19 patients covid-19-patients" training-from-dost-xi/" January 17
against-anti-vaxxers-amid-covid-19- January 17 Radyo Pilipinas 7AM, DZRB" "Research Methods Expert Clinical
surge/" Philippine Star "UP researchers recommend lagundi "3 RHUs In Davao Oriental Receive Trial - Dr. Cecilia Maramba-Lazarte
https://www.philstar.com/ for COVID-19 patients RxBox And Training From DOST-XI "Posibleng mawala ang mild January 18
"VCO vs COVID-19, isinusulong ng headlines/2022/01/17/2154343/ January 17 January 17 symptoms ng Covid-19 gamit ang Kabayan, DZMM"
DOST-PCHRD researchers-recommend-lagundi- Philippine Star Page One tamang dosage ng lagundi
January 16 covid-19-patients" https://www.philstar.com/ http://pageone.ph/3-rhus-in-davao- January 17 "DOST Vaccine Expert Panel - Chair
DWIZ 882 AM headlines/2022/01/17/2154343/ oriental-receive-rxbox-and-training- ACS Balita, DZRH AM" Dr. Niña Gloriani
https://www.dwiz882am.com/index. "UP researchers recommend lagundi researchers-recommend-lagundi- from-dost-xi/" January 19
php/vco-vs-covid-19-isinusulong-ng- for COVID-19 patients covid-19-patients" "Komentaryo sa Lagundi at VCO On The Spot, DZMM Teleradyo"
dost-pchrd/" January 17 "3 RHUs In Davao Oriental Receive January 17
Philippine Star "UP researchers recommend lagundi RxBox And Training From DOST-XI Karambola, DWIZ" "Vaccine Expert : Bakunadong nagka-
"DOST eyes VCO nasal inhaler, mouth https://www.philstar.com/ for COVID-19 patients January 17 COVID , mataas ang immunity
wash vs COVID-19 headlines/2022/01/17/2154343/ January 17 The Philippine Post "RHRDC-11 announces P1-M research January 19
January 16 researchers-recommend-lagundi- Atin Ito News http://thephilippinepost.com/3-rhus- funding grant Balita Ngayon, DZMM Teleradyo"
24 Pilipinas covid-19-patients" http://www.atinitonews.com/2022/01/ in-davao-oriental-receive-rxbox-and- January 18
https://www.24pilipinas.com/lifestyle/ up-researchers-recommend-lagundi- training-from-dost-xi/" The Manila Times "DOST Vaccine Expert Panel - Chair
dost-eyes-vco-nasal-inhaler-mouth- "UP researchers recommend lagundi for-covid-19-patients/" https://www.manilatimes. Dr. Niña Gloriani
wash-vs-covid-19/301618-news" for COVID-19 patients "3 RHUs In Davao Oriental Receive net/2022/01/18/public-square/rhrdc- January 19
January 17 "UP researchers recommend lagundi RxBox And Training From DOST-XI 11-announces-p1-m-research-funding- On The Spot, DZMM"
"Potensyal na paggamit ng VCM Philippine Star for COVID-19 patients January 17 grant/1829642"
January 16 https://www.philstar.com/ January 17 The Visayas Journal "Panayam kay Dr. Rontgene Solante ,
IZ Balita Nationwide Tanghali Edition, headlines/2022/01/17/2154343/ MSN News http://thevisayasjournal.com/3-rhus- "TELEMEDICINE DEVICE Infectious Disease Expert
DWIZ" researchers-recommend-lagundi- https://www.msn.com/en-ph/news/ in-davao-oriental-receive-rxbox-and- January 18 January 19
covid-19-patients" national/up-researchers-recommend- training-from-dost-xi/" Regions, Manila Times" Round Up, DZBB"
"VCM, malaki ang potensyal panlaban lagundi-for-covid-19-patients/ar-
sa COVID-19 "UP researchers recommend lagundi AASQ5AU" "3 RHUs In Davao Oriental Receive "RHRDC-11 announces P1-M research "Vaccine Expert : Bakunadong nagka-
January 16 for COVID-19 patients RxBox And Training From DOST-XI funding grant COVID , mataas ang immunity
IZ Balita Nationwide Umagang Edition, January 17 "UP researchers recommend lagundi January 17 January 18 January 19
DWIZ" Philippine Star for Pandemic patients Woman Public Square, Manila Times" Balita Ngayon, DZMM"
https://www.philstar.com/ January 17 http://woman.ph/3-rhus-in-davao-
"UP researchers recommend lagundi headlines/2022/01/17/2154343/ Trending PH oriental-receive-rxbox-and-training- "Vaccine Expert Panel Chairperson, "3 lugar sa NCR, ongoing ang mix and
for COVID patients researchers-recommend-lagundi- http://trendingph.net/up-researchers- from-dost-xi/" Dr. Nina Gloriani - mga fake news match vaccination trial
patungkol sa mga siyung may January 20
 262 PCHRD ANNUAL REPORT 2022 ANNEXES 263

IZ Balita Nationwide Hapong Edition, Mata ng Agila, Net 25" lagundi-vco-natural-remedy-against- covid-19 na pinagamit ng Lagundi mga VCO producers January 21
DWIZ" mild-covid-19-symptoms-dost/" January 21 January 21 Ito Ang Balita (IAB), UNTV"
"DOST: Lagundi, VCO help relieve mild Umaga Na Balita Na, DZBB" Network Balita, DZRB"
"Pag-inom ng VCO , napatunayan covid symptoms "Got mild COVID symptoms? Try virgin "Mix and match vaccination trials ng
sa pag-aaral na nakakabawas ng January 20 coconut oil, says DOST "Umuusad na ang mix and match trial "Lagundi at VCO, pwedeng inumin DOST, umuusad na sa tatlong lungsod
sintomas ng COVID-19 The Final Word, CNN Philippines TV" January 20 ng bakunahan ng DOST para maibsan ang mga sintomas dulot sa NCR
January 20 Yahoo News January 21 ng Covid-19 January 21
Super Balita sa Hapon Nationwide, "Got mild COVID symptoms? Try virgin https://ph.news.yahoo.com/got-mild- Umaga Na Balita Na, DZBB" January 21 Melo Del Prado sa Super Radyo,
DZBB" coconut oil, says DOST covid-symptoms-try-150529316.html" Radyo Pilipinas 7AM, DZRB" GMANEWSTV"
January 20 "DOST , isusulong ang pag-gamit ng
"Lagundi at Virgin Coconut Oil, Coconuts Manila "Taking virgin coconut oil may help VCO at lagundi para maibsan ang mga "Lagundi, VCO nakakatulong para "Pag-inom ng Virgin Coconut Oil,
epektibo sa mild COVID-19 symptoms https://coconuts.co/manila/news/ reduce COVID-19 symptoms -- DOST sintomas ng COVID-19 labanan ang mild covid symptoms nakatutulong para mabawasan ang
ayon sa pag-aaral got-mild-covid-symptoms-try-virgin- January 20 January 21 January 21 sintomas ng covid-19, batay sa pag-
January 20 coconut-oil-says-dost/" Front Page Super Balita sa Hapon Nationwide, Pangunahing Balita, DZRH AM" aaral ng DOST
RMN News Nationwide: The Sound of http://frontpageph.com/taking-virgin- DZBB" January 21
the Nation (5:30 PM), DZXL" "Lagundi at VCO, 'natural remedy' coconut-oil-may-help-reduce-covid-19- "DOST , pormal nang inirekomenda Melo Del Prado sa Super Radyo,
laban sa mild COVID-19 symptoms - symptoms-dost/" "VCO, napatunayang nakakatulong ang pag-gamit ng VCO para tugunan GMANEWSTV"
"Pag-aaral ng mga eksperto sa pag- DOST para maibsan ang sintomas ng ang mild at moderate symptoms ng
gamit ng lagundi sa mga mild case January 20 "Balik-scientist program ng DOST at covid-19 COVID-19 "Lagundi, VCO nakakatulong para
ng COVID-19 , maganda ang naging RMN iba pang programa ukol sa research January 21 January 21 labanan ang mild covid symptoms
resulta - DOST https://rmn.ph/lagundi-at-vco-natural- ang development dapat tuloy-tuloy- Umaga Na Balita Na, DZBB" TV Patrol, DZMM" January 21
January 20 remedy-laban-sa-mild-covid-19- Teodoro Pangunahing Balita, DZRH TV"
Bigtime Balita, DZBB" symptoms-dost/" Janaury 20 "DOST , inirerekomenda ang VCO para "Virgin Coconut Oil, mabisang
RH Balita, DZRH TV" tugunan ang mild at moderate COVID panlaban sa mild na kaso ng Covid-19 "DOST , pormal nang inirekomenda
"Mix and match trial ng COVID-19 "Virgin coconut oil helps in mild January 21 January 21 ang pag-gamit ng VCO para tugunan
vaccine ng DOST, umuusad na Covid-19 relief "Pag-aaral ng DOST sa herbal Balita Ngayon, DZMM" Kada Umaga, Net 25" ang mild at moderate symptoms ng
January 20 January 20 medicine kontra COVID-19, maganda COVID-19
Radyo Pilipinas, DZRB" Philippine Times ang resulta "Pag-inom ng Virgin Coconut Oil, "Trial sa mix and match ng Covid-19 January 21
https://www.philippinetimes.com/ January 20 nakatutulong para mabawasan ang vaccine, isinasagawa sa 3 lugar TV Patrol, ANC"
"VCO, napatunayang nakakatulong news/272215004/virgin-coconut-oil- One Balita Ngayon, One PH" sintomas ng covid-19, batay sa pag- January 21
upang maibsan ang sintomas ng helps-in-mild-covid-19-relief" aaral ng DOST Kada Umaga, Net 25" "DOST , pormal nang inirekomenda
COVID-19 ayon sa DOST "Trial ng mix and match ng COVID-19 January 21 ang pag-gamit ng VCO para tugunan
January 20 "Lagundi, VCO ‘natural remedy’ vs mild vaccine, isinasagawa sa 3 lugar - Melo Del Prado sa Super Radyo, "Virgin coconut oil, nakatutulong sa ang mild at moderate symptoms ng
Radyo Pilipinas, DZRB" COVID symptoms – DOST DOST DZBB" paggaling ng mga mild COVID-19 COVID-19
January 20 January 20 symptoms base sa pag-aaral ng DOST January 21
"Mix and match vaccination trials , Remate Online Balitalakayan, Net 25" "Mix and match vaccination trials ng January 21 TV Patrol, DZMM Teleradyo"
ginagawa na sa tatlong lugar sa Metro https://www.remate.ph/lagundi- DOST, umuusad na sa tatlong lungsod Dapat Alam Mo!, GMANEWSTV"
Manila vco-natural-remedy-vs-mild-covid- "Balik-scientist program ng DOST at sa NCR "Vaccine Development Expert Panel
January 20 symptoms-dost/" iba pang programa ukol sa research January 21 "Publiko , binalaan ng ilang eksperto Head, Dr. Nina Gloriani - natural
Super Radyo Nobela, DZBB" ang development dapat tuloy-tuloy- Melo Del Prado sa Super Radyo, laban sa mga gustong magpahawa ng immunty, maaaring maging epekto ng
"Virgin coconut oil helps in mild Teodoro DZBB" COVID para magkaroon ng immunity breakthrough infections
"VCO, napatunayang nakakatulong Covid-19 relief January 20 January 21 January 21
para maibsan ang sintomas ng January 20 RH Balita, DZRH AM" "Mix and match vaccine trial Balita Ngayon, DZMM Teleradyo" Public Briefing Laging Handa
covid-19 Philippine News Agency nagpapatuloy sa piling lugar sa Metro Philippines, PTV 4"
January 20 https://www.pna.gov.ph/ "Pag-aaral ng DOST sa herbal Manila "DOST , inirerekomenda ang VCO para
Super Balita sa Tanghali Nationwide, articles/1166000" medicine kontra COVID-19, maganda January 21 tugunan ang mild at moderate COVID "Pag-inom ng lagundi capsules para sa
DZBB" ang resulta RMN News Nationwide: The Sound of January 21 relief ng mild COVID, rekomendado ng
"Lagundi, VCO 'natural remedy' against January 20 the Nation (7 AM), DZXL" Balita Ngayon, DZMM Teleradyo" DOST-FNRI
"Virgin Coconut Oil, mabisang mild COVID-19 symptoms - DOST One Balita Ngayon, Radyo 5" January 21
panlaban sa mild na kaso ng COVID-19 January 20 "Magagawa ng VCO para maibsan ang "Mga fully vaccinated vs COVID-19, Saksi, GMA 7"
- DOST Manila Bulletin "Walang naitalang adverse effect sa sintomas ng mild Covid-19 cases, maari hindi dapat maging kampante- Dr.
January 20 https://mb.com.ph/2022/01/20/ mga participant na may mild case ng nang ilagay sa product packaging ng Nina Gloriani "Pag-inom ng virgin coconut oil at
 264 PCHRD ANNUAL REPORT 2022 ANNEXES 265

lagundi, inirerekomenda ng DOST- net/2022/01/21/virgin-coconut-oil- Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild cases-ng-covid-19-dost"
FNRI sa mga mild COVID patients helps-in-mild-covid-19-relief/" https://www.philstar.com/pang-masa/ January 21 cases ng COVID -19 - DOST
January 21 police-metro/2022/01/21/2155333/ Philippine Star January 21 "DOST provides updates on 'mix and
State of the Nation, GMANEWSTV" "DOST: Lagundi proven effective in lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- Philippine Star match' vaccine study
relieving symptoms in mild COVID-19 symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star- January 21
"UP RESEARCHERS: LAGUNDI based on latest clinical trial results lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/ Manila Bulletin
EASES COVID19 SYMPTOMS January 21 "Lagundi, VCO nakakatulong vs mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- https://mb.com.ph/2022/01/21/dost-
January 21 Eagle News symptoms ng COVID-19 - DOST cases-ng-covid-19-dost" provides-updates-on-mix-and-match-
The Post http://www.eaglenews.ph/dost- January 21 "Lagundi at VCO nakakatulong sa mild vaccine-study/"
https://thepost.net.ph/news/nation/ lagundi-proven-effective-in-relieving- Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild
up-researchers-lagundi-eases-covid19- symptoms-in-mild-covid-19-based-on- https://www.philstar.com/pang-masa/ January 21 cases ng COVID -19 - DOST "VCO not a 'replacement' for
symptoms/" latest-clinical-trial-results" police-metro/2022/01/21/2155333/ Philippine Star January 21 COVID-19 vaccine, says expert
lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- Philippine Star January 21
"Mix-and-match"" vaccination trials "Lagundi, VCO nakakatulong vs mild symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star- Manila Bulletin
underway in three Metro Manila areas symptoms ng COVID-19 - DOST lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/ https://mb.com.ph/2022/01/21/
January 21 January 21 "Lagundi, VCO nakakatulong vs mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- vco-not-a-replacement-for-covid-19-
Front Page Philippine Star symptoms ng COVID-19 - DOST cases-ng-covid-19-dost" vaccine-says-expert/"
http://frontpageph.com/mix-and- https://www.philstar.com/pang-masa/ January 21 "Lagundi at VCO nakakatulong sa mild
match-vaccination-trials-underway-in- police-metro/2022/01/21/2155333/ Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild "Direct intake of VCO alleviates mild,
three-metro-manila-areas/" lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pang-masa/ January 21 cases ng COVID -19 - DOST moderate COVID-19 symptoms -
symptoms-ng-covid-19-dost" police-metro/2022/01/21/2155333/ Philippine Star January 21 DOST
"Here’s how you can use the Lagundi lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- Philippine Star January 21
syrup or tablet if you’re diagnosed with "Lagundi, VCO nakakatulong vs mild symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star- Manila Bulletin
mild COVID-19 symptoms ng COVID-19 - DOST lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/ https://mb.com.ph/2022/01/21/
January 21 January 21 "Lagundi, VCO nakakatulong vs mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- direct-intake-of-vco-alleviates-mild-
PTV News Philippine Star symptoms ng COVID-19 - DOST cases-ng-covid-19-dost" moderate-covid-19-symptoms-dost/"
https://www.ptvnews.ph/heres-how- https://www.philstar.com/pang-masa/ January 21 "Lagundi at VCO nakakatulong sa mild
you-can-use-the-lagundi-syrup-or- police-metro/2022/01/21/2155333/ Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild "DOST: VCO inirekomenda para sa
tablet-if-youre-diagnosed-with-mild- lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pang-masa/ January 21 cases ng COVID -19 - DOST mild COVID symptoms
covid-19/" symptoms-ng-covid-19-dost" police-metro/2022/01/21/2155333/ Philippine Star January 21 January 21
lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- Philippine Star ABSCBN News
"Virgin coconut oil helps in mild "Lagundi, VCO nakakatulong vs mild symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star- https://news.abs-cbn.com/
Covid-19 relief symptoms ng COVID-19 - DOST lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/ news/01/21/22/dost-vco-
January 21 January 21 "Lagundi at VCO nakakatulong sa mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- inirekomenda-para-sa-mild-covid-
Manila News Philippine Star cases ng COVID -19 - DOST cases-ng-covid-19-dost" symptoms"
https://www.manilanews.net/ https://www.philstar.com/pang-masa/ January 21 "Lagundi at VCO nakakatulong sa mild
news/272215004/virgin-coconut-oil- police-metro/2022/01/21/2155333/ Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild "Lagundi, VCO effective in treating
helps-in-mild-covid-19-relief" lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- January 21 cases ng COVID -19 - DOST mild COVID-19 symptoms - DOST
symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ Philippine Star January 21 January 21
"Lagundi at VCO, epektibo vs mild lagundi-vco-nakakatulong-sa-mild- https://www.philstar.com/pilipino-star- Philippine Star Views Features, Manila Bulletin"
COVID-19 symptoms - DOST "Lagundi, VCO nakakatulong vs mild cases-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star-
January 21 symptoms ng COVID-19 - DOST lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/ "VCO effective in mild Covid cases'
SMNI News Channel January 21 "Lagundi at VCO nakakatulong sa mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- January 22
http://www.smninewschannel.com/ Philippine Star cases ng COVID -19 - DOST cases-ng-covid-19-dost" News, Manila Times"
lagundi-at-vco-epektibo-vs-mild-covid- https://www.philstar.com/pang-masa/ January 21 "Lagundi at VCO nakakatulong sa mild t
19-symptoms-dost" police-metro/2022/01/21/2155333/ Philippine Star cases ng COVID -19 - DOST "Lagundi at VCO nakakatulong sa mild "Direct intake of VCO alleviates mild,
lagundi-vco-nakakatulong-vs-mild- https://www.philstar.com/pilipino-star- January 21 cases ng COVID -19 - DOST moderate COVID-19 symptoms, study
"Virgin coconut oil helps in mild symptoms-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ Philippine Star January 21 shows
Covid-19 relief lagundi-vco-nakakatulong-sa-mild- https://www.philstar.com/pilipino-star- Philippine Star January 22
January 21 "Lagundi, VCO nakakatulong vs mild cases-ng-covid-19-dost" ngayon/bansa/2022/01/21/2155331/ https://www.philstar.com/pilipino-star- Views Features, Manila Bulletin"
Canadian Inquirer symptoms ng COVID-19 - DOST lagundi-vco-nakakatulong-sa-mild- ngayon/bansa/2022/01/21/2155331/
https://canadianinquirer. January 21 "Lagundi at VCO nakakatulong sa mild cases-ng-covid-19-dost" lagundi-vco-nakakatulong-sa-mild- "VCO alleviates mild, moderate
 266 PCHRD ANNUAL REPORT 2022 ANNEXES 267

COVID-19 symptoms - DOST "DOST-PCHRD, Medical Research https://cebudailynews.inquirer. "DOST-FNRI lumabas sa pag-aaral dost"
January 22 January 22 Council-UK collaborate for research net/421616/covid-survivor-swears-by- na nakakabawas ang VCO ng mild at "UP Visayas Philippine Genome
News, Manila Bulletin" MSN News projects on infectious diseases lagundi-efficacy-vs-mild-symptoms" moderate symtoms ng Covid-19 cases Center acquires country's 1st Next-
https://www.msn.com/en-ph/news/ January 23 January 25 Gen Sequencers for COVID
"DOST studies confirm virgin coco oil technology/virgin-coconut-oil-lagundi- 24 Pilipinas "VCO kumpirmadong nakababawas IZ Balita Nationwide Umagang Edition, January 27
can help ease COVID symptoms can-help-patients-with-mild-covid-19- https://www.24pilipinas.com/lifestyle/ ng COVID symptoms – DOST DWIZ" Good News Pilipinas
January 22 study/ar-AAT0Nrv" dost-pchrd-medical-research-council- January 24 http://www.goodnewspilipinas.com/
News, Philippine Daily Inquirer" uk-collaborate-for-research-projects- Remate Online "DOST-FNRI lumabas sa pag-aaral up-visayas-philippine-genome-center-
"Virgin coconut oil, makatutulong vs on-infectious-diseases/303733-news" https://www.remate.ph/vco- na nakakabawas ang VCO ng mild at acquires-countrys-1st-next-gen-
"DOST studies confirm virgin coco oil mild COVID-19 cases kumpirmadong-nakababawas-ng- moderate symtoms ng Covid-19 cases sequencers-for-covid"
can help ease COVID symptoms January 22 "2nd VCO study confirms faster patient covid-symptoms-dost/" January 25
January 22 Balita recovery from mild to moderate IZ Sa Alas Sais, DWIZ" "PGC Visayas hopes for faster COVID
Philippine Daily Inquirer https://balita.net.ph/2022/01/22/virgin- Covid-19 "DOST: VCO helps treat mild, variant detection with new machines
https://newsinfo.inquirer.net/1543457/ coconut-oil-makatutulong-vs-mild- January 23 moderate COVID-19 symptoms "Panayam kay Dr. Nina Gloriani, DOST January 29
dost-studies-confirm-virgin-coco-oil- covid-19-cases/" Business Mirror January 24 Vaccine Development Expert Panel Daily Guardian
can-help-ease-covid-symptoms" https://businessmirror.com. CNN Philippines Head https://dailyguardian.com.ph/pgc-
"FIRST OF ITS KIND IN PHL: PGC- ph/2022/01/23/2nd-vco-study- https://cnnphilippines.com/ January 25 visayas-hopes-for-faster-covid-variant-
"VCO effective in mild Covid cases' Visayas acquires high tech genome confirms-faster-patient-recovery-from- videos/2022/1/24/DOST--VCO-helps- Damdaming Bayan, DZRH AM" detection-with-new-machines/"
January 22 sequencers mild-to-moderate-covid-19/" treat-mild--moderate-COVID-19-
The Manila Times January 22 symptoms.html" "DOST Vaccine Expert - Dr. Nina "6,480 participants of WHO solidarity
https://www.manilatimes. Daily Guardian "DOST-PCHRD, Medical Research Gloriani trials get first dose of COVID-19 jabs
net/2022/01/22/news/national/vco- https://dailyguardian.com.ph/first-of- Council-UK collaborate for research "DOST studies confirm VCO eases January 25 January 29
effective-in-mild-covid-cases/1830206" its-kind-in-phl-pgc-visayas-acquires- projects on infectious diseases COVID-19 symptoms Straight to the Point, DZXL" Manila Bulletin
high-tech-genome-sequencersx/" January 23 January 24 https://mb.com.ph/2022/01/29/6480-
"VCO, puwede sa mild COVID-19 cases Manila Bulletin Manila Bulletin "Panayam kay Dr. Nina Gloriani, DOST participants-of-who-solidarity-trials-
January 22 "Virgin coconut oil, lagundi can help https://mb.com.ph/2022/01/23/dost- https://mb.com.ph/2022/01/24/dost- Vaccine Development Expert Panel get-first-dose-of-covid-19-jabs/"
Daily Tribune patients with mild COVID-19 — study pchrd-medical-research-council-uk- studies-confirm-vco-eases-covid-19- Head
https://tribune.net.ph/index. January 22 collaborate-for-research-projects-on- symptoms/" January 25 "6,480 participant ng WHO solidarity
php/2022/01/22/vco-puwede-sa-mild- GMA News Online infectious-diseases/" Damdaming Bayan, DZRH TV" trials naturukan na ng 1st dose
covid-19-cases/" https://www.gmanetwork.com/ "COVID SURVIVOR SWEARS BY January 29
news/scitech/science/819058/virgin- "COVID survivor swears by 'lagundi' 'LAGUNDI' EFFICACY VS MILD "Caution urged to prevent overdose of Remate Online
"Virgin coconut oil, lagundi can help coconut-oil-lagundi-can-help-mild- efficacy vs mild symptoms SYMPTOMS lagundi as treatment for mild Covid http://www.remate.ph/6480-
patients with mild COVID-19 -- study covid-19-patients-study/story/" January 24 January 24 January 25 participant-ng-who-solidarity-trials-
January 22 Philippine Daily Inquirer Front Page, Philippine Daily Inquirer" Public Square, Manila Times" naturukan-na-ng-1st-dose"
MSN News "DOST: VCO helps treat symptoms of https://newsinfo.inquirer.net/1544052/
https://www.msn.com/en-ph/news/ mild, moderate COVID-19 cases covid-survivor-swears-by-lagundi- "Panayam Kay Dr. Nina Gloriani, DOST "Caution urged to prevent overdose of "DOST-Vaccine Expert Panel -
technology/virgin-coconut-oil-lagundi- January 22 efficacy-vs-mild-symptoms" Vaccine Development Expert Panel lagundi as treatment for mild Covid Chairperson Dr. Nina Gloriani
can-help-patients-with-mild-covid- CNN Philippines Head January 25 January 29
19-%25e2%2580%2594-study/ar- https://www.cnn.ph/news/2022/1/22/ "DOST: VCO helps treat sysmptoms of January 24 The Manila Times Your Daily Do's, DZMM Teleradyo"
AAT0Nrv" DOST-virgin-coconut-oil.html" mild, moderate sysmptoms Dos Por Dos, DZRH TV" https://www.manilatimes.
January 24 "Panayam Kay Dr. Nina Gloriani, DOST net/2022/01/25/public-square/ "DOST-Vaccine Expert Panel -
"How to Take Lagundi for Mild COVID "DOST inirekomenda ang VCO sa mild, New Day, CNN Philippines TV" Vaccine Development Expert Panel caution-urged-to-prevent-overdose- Chairperson Dr. Nina Gloriani
Symptoms, from DOST moderate symtoms ng Covid Head of-lagundi-as-treatment-for-mild- January 29
January 22 January 22 "DOST: VCO helps treat mild, moderate January 24 covid/1830463" Your Daily Do's, DZMM"
MSN Lifestyle Teleradyo Balita, DZMM Teleradyo" COVID-19 symptoms Dos Por Dos, DZRH AM"
https://www.msn.com/en-ph/health/ January 24 "VCO kumpirmadong nakababawas "DOST targets P6.79-B fund for 304
medical/how-to-take-lagundi-for- News Night, CNN Philippines TV" "DOST-FNRI lumabas sa pag-aaral ng COVID symptoms - DOST R&D projects in 2024
mild-covid-symptoms-from-dost/ar- "DOST inirekomenda ang VCO sa mild, na nakakabawas ang VCO ng mild at January 25 January 30
AASZKsG" moderate symtoms ng Covid "COVID survivor swears by 'lagundi' moderate symtoms ng Covid-19 cases DWIZ 882 AM Science Sunday, Business Mirror"
January 22 efficacy vs mild symptoms January 25 http://www.dwiz882am.com/
"Virgin coconut oil, lagundi can help Teleradyo Balita, DZMM" January 24 Balitang Todo Lakas, DWIZ" index.php/vco-kumpirmadong- "DOST-PCHRD names recipients of
patients with mild COVID-19 -- study Cebu Daily News Inquirer nakababawas-ng-covid-symptoms- AROHRA
 268 PCHRD ANNUAL REPORT 2022 ANNEXES 269

January 30 Nina Gloriani February 7 https://www.manilanews.net/ "Mga immunocompromised, maaaring "Panayam kay Dr. Nina Gloriani,
Manila Bulletin February 4 Public Square, Manila Times" news/272274543/dost-up-toronto- maturukan ng ika-4 na dose ng bakuna Vaccine Expert Panel Head, DOST
https://mb.com.ph/2022/01/30/dost- IZ Sa Alas Sais, DWIZ" experts-developing-new-covid-19-test- kontra covid-19 bilang booster shot, February 16
pchrd-names-recipients-of-arohra/" "DOST, UP, Toronto experts developing kits" ayon sa isang eksperto Mata ng Agila, Net 25"
"UP Manila kasalukuyang gumagawa new Covid-19 test kits February 14
"UP's psychological services ng novel cell-based immunosafety February 7 "DOST, UP, Toronto Experts Developing Super Balita sa Umaga Nationwide, "DOST Vaccine Expert Panel -
recognized for addressing mental platform para sa serologic testing ng Philippine News Agency New Covid-19 Test Kits DZBB" Chairperson Dr. Nina Gloriani
healthcare needs of students, faculty Covid-19 https://www.pna.gov.ph/ February 8 February 16
January 31 February 5 articles/1167243" Pinoy Feeds "Mga immunocompromised, maaaring On The Spot, DZMM"
24 Pilipinas IZ Balita Nationwide Sabado (Pang- http://pinoyfeeds.com/dost-up- maturukan ng ika-4 na dose ng bakuna
https://www.24pilipinas.com/ Hapong Edisyon), DWIZ" "DOST, UP, Toronto experts developing toronto-experts-developing-new- kontra covid-19 bilang booster shot, "Researchers provided with free
lifestyle/ups-psychological-services- new Covid-19 test kits covid-19-test-kits/" ayon a vaccine expert panel ng DOST session on Intellectual Property by
recognized-for-addressing-mental- "UP Manila kasalukuyang gumagawa February 7 February 14 DOST
healthcare-needs-of-students- ng novel cell-based immunosafety Manila News "PUHUNAN SA PHARMA Melo Del Prado sa Super Radyo, February 17
faculty/306021-news" platform para sa serologic testing ng http://manilanews.ph/dost-up-toronto- DAGDAGAN - DOST DZBB" Philippine Information Agency
Covid-19 experts-developing-new-covid-19-test- February 10 https://pia.gov.ph/press-
"VCO trials vs Pandemic yield positive February 5 kits/" Lifestyle, Abante" "Mga immunocompromised, maaaring releases/2022/02/17/researchers-
results, says DOST IZ Balita Nationwide Sabado (Pang- maturukan ng ika-4 na dose ng bakuna provided-with-free-session-on-
February 1 Tanghaling Edisyon), DWIZ" "DoST-PCHRD honors medical "UP MANILA AND UNIVERSITY kontra covid-19 bilang booster shot, intellectual-property-by-dost"
Trending PH scientist Jose Rizal OF TORONTO DEVELOPING NEW ayon sa isang eksperto
http://trendingph.net/vco-trials-vs- "Development of cell-based COVID-19 February 7 COVID19 TEST KIT February 14 "Panayam kay DOST Vaccine Expert
covid-19-yield-positive-results-says- test eyed MSN News February 11 Super Balita sa Umaga, Dr. Niña Gloriani
dost/" February 5 https://www.msn.com/en-ph/news/ The Post GMANEWSTV" February 17
24 Pilipinas other/dost-pchrd-honors-medical- https://thepost.net.ph/news/campus/ Centro Serbisyo, DZXL"
"VCO trials vs COVID yield positive https://www.24pilipinas.com/lifestyle/ scientist-jose-rizal/ar-AATxd72" up-manila-and-university-of-toronto- "Mga immunocompromised, maaaring "Manila HealthTek, Philippines' Covid-19
results, says DOST development-of-cell-based-covid-19- developing-new-covid19-test-kit/" maturukan ng ika-4 na dose ng bakuna RT-PCR test kit maker, acquires ISO
February 1 test-eyed/307573-news" "Balik-scientist program ng DOST kontra covid-19 bilang booster shot, February 18
Business, Philippine Star" February 7 "Aspiring scientists urged to 'find their ayon a vaccine expert panel ng DOST Punto Central Luzon
"VCO trials vs COVID-19 yield positive "UP Manila, kasalukuyang gumagawa Newsroom Ngayon, CNN Philippines perfect match' through Balik Scientist February 14 https://punto.com.ph/manila-
results, says DOST ng Novel Cell-Based Immunoassay TV" Program Melo Del Prado sa Super Radyo, healthtek-philippines-covid-19-rt-pcr-
February 1 Platform para sa testing ng COVID-19 February 12 GMANEWSTV" test-kit-maker-acquires-iso/"
24 Pilipinas February 5 "DOST, UP, Toronto experts developing Manila Bulletin
https://www.24pilipinas.com/business/ DWIZ 882 AM new Covid-19 test kits https://mb.com.ph/2022/02/12/ "DOST may programa sa mga Pinoy "Brand & Business: Manila HealthTek,
vco-trials-vs-covid-19-yield-positive- https://www.dwiz882am.com/index. February 7 aspiring-scientists-urged-to-find-their- scientist Philippines' COVID-19 RT-PCR test kit
results-says-dost/306241-news" php/up-manila-kasalukuyang- Manila News perfect-match-through-balik-scientist- February 15 maker, acquires ISO - adobo Magazine
gumagawa-ng-novel-cell-based- https://www.manilanews.net// program/" Editorial, Abante Tonite" Online
"VCO trials vs COVID-19 yield positive immunoassay-platform-para-sa- news/272274543/dost-up-toronto- February 18
results, says DOST testing-ng-covid-19/" experts-developing-new-covid-19-test- "DOST, UP at Toronto experts is "Panayam kay Dr. Nina Gloriani, DOST Adobo Magazine
February 1 kits" developing new Covid-19 test kits Vaccine Development Expert Panel https://adobomagazine.com/
Philippine Star "Development of cell-based COVID-19 February 12 Head philippine-news/brand-business-
https://www.philstar.com/ test underway "DOST, UP, Toronto experts developing Regional Round-up, DZRB" February 15 manila-healthtek-philippines-covid-19-
business/2022/02/01/2157655/vco- February 5 new Covid-19 test kits ACS Balita, DZRH TV" rt-pcr-test-kit-maker-acquires-iso/"
trials-vs-covid-19-yield-positive-results- Manila Bulletin February 8 "Panayam kay Dr. Nina Gloriani , DOST-
says-dost" https://mb.com.ph/2022/02/05/ Philippine Times VEP Chairperson "Panayam kay Dr. Nina Gloriani, DOST "Philippines' Covid-19 RT-PCR test kit
development-of-cell-based-covid-19- https://www.philippinetimes.com/ February 13 Vaccine Development Expert Panel maker Manila HealthTek acquires ISO
"VCO trials vs COVID-19 yield positive test-underway/" news/272274543/dost-up-toronto- Buena Manong Balita, DZBB" Head nod
results, says DOST experts-developing-new-covid-19-test- February 15 February 18
February 1 "More investments in pharma needed kits" "Puwedeng bakunahan ng ikaapat na ACS Balita, DZRH AM" Good News Pilipinas
MSN Lifestyle February 6 dose ng bakuna kontra covid-19 ang http://www.goodnewspilipinas.com/
https://www.msn.com/en-ph/health/ Opinion, Peoples Journal" "DOST, UP, Toronto experts developing mga immunocompromised "DOST Vaccine Expert Panel - philippines-covid-19-rt-pcr-test-kit-
medical/vco-trials-vs-covid-19-yield- new Covid-19 test kits February 14 Chairperson Dr. Nina Gloriani maker-manila-healthtek-acquires-iso-
positive-results-says-dost/ar-AATkyfH" "DoST-PCHRD honors medical February 8 Balitang Balita, DZBB" February 16 nod/"
"Panayam kay Vaccine Expert Panel Dr. scientist Jose Rizal Manila News On The Spot, DZMM Teleradyo"
 270 PCHRD ANNUAL REPORT 2022 ANNEXES 271

"Philippines' Covid-19 RT-PCR test kit spread of airborne viruses MSN News kailanganin ayon sa Vaccine Expert "Regionsinbriefs: TAWI-TAWI news/272379764/pchrd-funds-
maker Manila HealthTek acquires ISO February 19 https://www.msn.com/en-ph/news/ February 24 RECEIVES 9 RXBOX DEVICES development-of-tool-to-assess-
nod Philippine News Agency national/dost-funds-usc-ventilation- TV Patrol, ANC" March 9 handwriting"
February 18 https://www.pna.gov.ph/ system-research-vs-viruses/ar- Regions, Manila Times"
MSN News articles/1168119" AAU65Bi" "UST receives grant from DOST for "RxBox aids monitoring of COVID-19
https://www.msn.com/en-ph/news/ National Mental Health Project 2021 "Tawi-Tawi receives 9 RxBox devices positive, pregnant women in health
national/philippines-covid-19-rt-pcr- "Low-cost ventilator eyed to stop "PGC-Visayas completes first March 1 March 9 facilities
test-kit-maker-manila-healthtek- spread of airborne viruses sequencing run for SARS-CoV-2 Manila Bulletin The Manila Times March 11
acquires-iso-nod/ar-AAU1YFo" February 19 Biosurveillance https://mb.com.ph/2022/03/01/ust- https://www.manilatimes. Panay News
Manila News February 22 receives-grant-from-dost-for-national- net/2022/03/09/news/regions/ http://www.panaynews.net/rxbox-
"Researchers provided with free https://www.manilanews.net/ Daily Guardian mental-health-project-2021/" tawi-tawi-receives-9-rxbox- aids-monitoring-of-covid-19-positive-
session on Intellectual Property by news/272314010/low-cost-ventilator- https://dailyguardian.com.ph/pgc- devices/1835580" pregnant-women-in-health-facilities/"
DOST eyed-to-stop-spread-of-airborne- visayas-completes-first-sequencing- "DOST chief hopes next admin will
February 18 viruses" run-for-sars-cov-2-biosurveillance/" focus on research, development "DOH, DOST, and UP-PGC work "RxBox aids monitoring of COVID-19
Tuklasin Natin March 2 together to expand the country's positive, pregnant women in health
https://tuklasinnatin.wordpress. "Murang ventilator system bubuuin ng "UNIVERSITY OF SAN CARLOS TO Manila Bulletin biosurveillance capacity facilities
com/2022/02/18/researchers- DOST, UCS DEVELOP LOW-COST SYSTEM VS https://mb.com.ph/2022/03/02/dost- March 10 March 11
provided-with-free-session- February 20 VIRUSES chief-hopes-next-admin-will-focus-on- Daily Guardian Business, The Daily Guardian"
on-intellectual-property-by- Remate Online February 22 research-development/" https://dailyguardian.com.ph/doh-
dost%ef%bf%bc/" https://www.remate.ph/murang- The Post dost-and-up-pgc-work-together-to- "RxBox aids monitoring of COVID-19
ventilator-system-bubuuin-ng-dost- https://thepost.net.ph/news/campus/ "UST receives grant from DoST for expand-the-countrys-biosurveillance- positive, pregnant women in health
"Panayam Kay Dr. Nina Gloriano, DOST ucs/" university-of-san-carlos-to-develop- mental health project capacity/" facilities
Vaccine Development Expert Panel low-cost-system-vs-viruses/" March 3 March 11
Head "Mas murang ventilator system, The Manila Times "Virology and Vaccine Institute, a must Business, Panay News"
February 18 planong buuin ng DOST-PCHRD "DoST provides researchers free https://www.manilatimes. in post-pandemic PH
Dos Por Dos, DZRH TV" February 20 webinar on IP net/2022/03/03/campus-press/ust- March 10 "Santo Tomas U gets DOST grant for
DWIZ 882 AM February 24 receives-grant-from-dost-for-mental- Opinion, Manila Times" Natl Mental Health Project ’21
"Panayam Kay Dr. Nina Gloriano, DOST https://www.dwiz882am.com/index. Public Square, Manila Times" health-project/1834939" March 12
Vaccine Development Expert Panel php/mas-murang-ventilator-system- "Virology and Vaccine Institute, a must Education, Business Mirror"
Head planong-buuin-ng-dost-pchrd" "DoST provides researchers free "DOST, Adamson team up to produce in post-pandemic PH
February 18 webinar on IP cost-efficient tablets for stroke patients "PGC Visayas starts SARS-CoV-2
Dos Por Dos, DZRH AM" "DOST Funds USC Ventilation System February 24 March 5 March 10 genome biosurveillance
Research Vs Viruses The Manila Times Manila Bulletin The Manila Times March 12
"DOST Vaccine Expert Panel Head - Dr. February 21 https://www.manilatimes. https://mb.com.ph/2022/03/05/dost- https://www.manilatimes. Daily Guardian
Nina Gloriani Pinoy Feeds net/2022/02/24/public-square/dost- adamson-team-up-to-produce-cost- net/2022/03/10/opinion/columns/ https://dailyguardian.com.ph/pgc-
February 19 http://pinoyfeeds.com/dost-funds- provides-researchers-free-webinar-on- efficient-tablets-for-stroke-patients/" virology-and-vaccine-institute-a-must- visayas-starts-sars-cov-2-genome-
Teleradyo Balita, DZMM" usc-ventilation-system-research-vs- ip/1834039" in-post-pandemic-ph/1835732" biosurveillance/"
"DOST Vaccine Expert Panel Head - Dr. viruses/" "7,083 WHO solidarity trials
Nina Gloriani "Dr. Gloriani; Variant specific na bakuna participants get first dose of Covid-19 "USC proposes Low-cost Air "Santo Tomas U gets DOST grant for
February 19 "DOST funds USC ventilation system posibleng hindi na kailangan vs jabs Ventilation System for Face-to-Face National Mental Health Project 2021
Teleradyo Balita, DZMM Teleradyo" research vs viruses Covid-19 March 7 Classes March 12
February 21 February 24 News, Manila Bulletin" March 10 Business Mirror
"Development of low-cost ventilator Philippine Star Headline Pilipinas, DZMM Teleradyo" Sugbo https://businessmirror.com.
system eyed https://www.philstar.com/ "DOST PROVIDES FUNDS FOR UST https://sugbo.ph/2022/usc-low-cost- ph/2022/03/12/santo-tomas-u-gets-
February 19 headlines/2022/02/21/2162243/dost- "DOST - Vaccine Expert Panel Head Dr. MENTAL HEALTH PROJECT air-ventilation/" dost-grant-for-national-mental-health-
Manila Bulletin funds-usc-ventilation-system-research- Nina Gloriani March 8 project-2021/"
http://mb.com.ph/2022/02/19/ vs-viruses" February 24 The Post "PCHRD funds development of tool to
development-of-low-cost-ventilator- Sakto, DZMM Teleradyo" https://thepost.net.ph/news/nation/ assess handwriting "PCHRD funds development of tool to
system-eyed" "DOST funds USC ventilation system dost-provides-funds-for-ust-mental- March 11 assess handwriting
research vs viruses "Mga variant specific na bakuna laban health-project/" Philippine Times March 12
"Low-cost ventilator eyed to stop February 21 sa COVID-19 , posibleng hindi na https://www.philippinetimes.com/ Manila News
 272 PCHRD ANNUAL REPORT 2022 ANNEXES 273

https://www.manilanews.net/ in-visayas-mindanao-now-ready-for- The Mindanao Life on 4th Covid-19 vax dose for elderly, "Recruitment for liver cancer detection "DOST may solusyon sa pagkabansot
news/272379764/pchrd-funds- genome-sequencing-doh/story/" http://themindanaolife.com/ immunocompromised study nears completion ng mga bata
development-of-tool-to-assess- "UP-PGC now ready for genome dost-pchrd-funds-a-tool-that-can- March 24 March 26 April 6
handwriting" sequencing in VisMin determine-handwriting-problems-in- Manila Bulletin Manila News Lifestyle, Abante"
"DOST funds tool to address March 16 children/" https://mb.com.ph/2022/03/24/ https://www.manilanews.net/
handwriting problems PTV News dost-vep-awaiting-decision-of-fda- news/272421233/recruitment-for- "Black garlic ice cream? Garlic, agri-
March 12 https://ptvnews.ph/up-pgc-now- "DOST-PCHRD Funds A Tool That Can on-4th-covid-19-vax-dose-for-elderly- liver-cancer-detection-study-nears- food condiments industry bloom with
Manila Bulletin ready-for-genome-sequencing-in- Determine Handwriting Problems In immunocompromised/" completion" DOST's NICER program
https://mb.com.ph/2022/03/12/dost- vismin/" Children April 11
funds-tool-to-address-handwriting- March 18 "Vaccine Expert Panel - Chairperson "DOST, UP Manila eye development of Manila Bulletin
problems/" "UP-PGC now ready for genome Manila Magazine Dr. Nina Gloriani AI-driven cancer detection tool https://mb.com.ph/2022/04/11/black-
sequencing in VISMIN http://mnlmag.com/dost-pchrd- March 24 March 27 garlic-ice-cream-garlic-agri-food-
"Bacolod: PGC Visayas starts SARS- March 16 funds-a-tool-that-can-determine- Sakto, DZMM Teleradyo" Manila Bulletin condiments-industry-bloom-with-
CoV-2 genome biosurveillance PIA MIMAROPA handwriting-problems-in-children/" https://mb.com.ph/2022/03/27/dost- dosts-nicer-program/"
March 13 https://pia4b.wordpress. "Vaccine Expert Panel - Chairperson up-manila-eye-development-of-ai-
RPN Radio com/2022/03/16/up-pgc-now-ready- "DOST-PCHRD Funds A Tool That Can Dr. Nina Gloriani driven-cancer-detection-tool/" "Black garlic ice cream?
https://rpnradio.com/bacolod-pgc- for-genome-sequencing-in-vismin/" Determine Handwriting Problems In March 24 April 12
visayas-starts-sars-cov-2-genome- Children Sakto, DZMM" "Recruitment for liver cancer detection Views Features, Manila Bulletin"
biosurveillance/" "Panayam kay Dr. Nina Gloriani, DOST March 18 study nears completion
Vaccine Development Expert Panel The Visayas Journal "Recruitment for liver cancer detection March 27 "DOST Vaccine Expert Panel - Chair
"Virologist Dr. Lourdes Nadala & Dr. Head http://thevisayasjournal.com/ study nears completion Canadian Inquirer Dr. Nina Gloriani
Myra Hosmillo- Pinay Scientists: PH March 17 dost-pchrd-funds-a-tool-that-can- March 25 https://canadianinquirer. April 22
needs virology & vaccine institute ACS Balita, DZRH TV" determine-handwriting-problems-in- Philippine News Agency net/2022/03/27/recruitment-for- On The Spot, DZMM Teleradyo"
March 14 children/" https://www.pna.gov.ph/ liver-cancer-detection-study-nears-
The Final Word, CNN Philippines TV" "Panayam kay Dr. Nina Gloriani, DOST articles/1170688" completion/" "DOST Vaccine Expert Panel - Chair
Vaccine Development Expert Panel "DOST-PCHRD Funds A Tool That Can Dr. Nina Gloriani
"DOST popondohan i-SULAT Head Determine Handwriting Problems In "Recruitment for liver cancer detection "MAAGANG PAGTUKLAS NG April 22
March 15 March 17 Children study nears completion KANSER SA ATAY On The Spot, DZMM"
Lifestyle, Abante" ACS Balita, DZRH AM" March 18 March 25 March 28
The Luzon Daily Manila News Lifestyle, Abante" "Panayam kay Dr. Nina Gloriani, DOST
"Genome sequencing ng COVID, kaya "DOST-PCHRD Funds A Tool That Can http://theluzondaily.com/dost-pchrd- http://manilanews.ph/recruitment-for- Vaccine Development Expert Panel
na sa Vis-Min Determine Handwriting Problems In funds-a-tool-that-can-determine- liver-cancer-detection-study-nears- "Panayam kay Dr. Nina Gloriani, DOST Head
March 15 Children handwriting-problems-in-children/" completion/" Vaccine Development Expert Panel April 25
Remate Online March 18 Head Dos Por Dos, DZRH TV"
https://www.remate.ph/genome- Woman "DOST-PCHRD Funds A Tool That Can "Recruitment for liver cancer detection March 29
sequencing-ng-covid-kaya-na-sa-vis- http://woman.ph/dost-pchrd-funds-a- Determine Handwriting Problems In study nears completion ACS Balita, DZRH TV" "Panayam kay Dr. Nina Gloriani, DOST
min/" tool-that-can-determine-handwriting- Children March 25 Vaccine Development Expert Panel
problems-in-children/" March 18 Philippine Times "Iloilo pharma firm gets DOST funding Head
"Genome sequencing ng SARS-CoV-2, Page One https://www.philippinetimes.com/ to develop lab grown human skin April 25
kaya na ng PGC sa UP Visayas at "DOST-PCHRD Funds A Tool That Can http://pageone.ph/dost-pchrd- news/272421233/recruitment-for- April 2 Dos Por Dos, DZRH AM"
Mindanao Determine Handwriting Problems In funds-a-tool-that-can-determine- liver-cancer-detection-study-nears- Daily Guardian
March 15 Children handwriting-problems-in-children/" completion" https://dailyguardian.com.ph/iloilo- "Panayam kay Dr. Nina Gloriani ,
Remate Online March 18 pharma-firm-gets-dost-funding-to- Vaccine Expert Panel Chairpreson
https://www.remate.ph/genome- The Philippine Post "UP-PGC now ready for genome "Recruitment for liver cancer detection develop-lab-grown-human-skin/" April 25
sequencing-ng-covid-kaya-na-sa-vis- http://thephilippinepost.com/ sequencing in VisMin study nears completion Dobol Weng Sa Dobol B, DZBB"
min/" dost-pchrd-funds-a-tool-that-can- March 20 March 25 "Study to address stunting in kids likely
determine-handwriting-problems-in- Philippine Information Agency Manila News done by 2023 "Member, DOST Vaccine Experts
"PGC labs in Visayas, Mindanao now children/" https://pia.gov.ph/press- https://www.manilanews.net// April 4 Panel Dr. Rontgene Solante-
ready for genome sequencing --DOH releases/2022/03/20/up-pgc-now- news/272421233/recruitment-for- Philippine News Agency Vaccination at booster rollout,
March 15 "DOST-PCHRD Funds A Tool That Can ready-for-genome-sequencing-in- liver-cancer-detection-study-nears- https://www.pna.gov.ph/ nananatiling mabagal ang usad
GMA News Online Determine Handwriting Problems In vismin" completion" articles/1171390" April 26
https://www.gmanetwork.com/news/ Children
topstories/nation/825129/pgc-labs- March 18 "DOST-VEP awaiting decision of FDA
 2 74 PCHRD ANNUAL REPORT 2022 ANNEXES 275

Frontline Tonight, TV 5" May 3 Catanduanes Longer Push Through https://www.bomboradyo.com/ trial-sa-ivermectin-hindi-na-itutuloy/"
Philippine Times May 13 May 20 clinical-trial-ng-kontrobersiyal-na-anti-
"Aminado si Dr. Nina Gloriani, na https://www.philippinetimes.com/ Bicol Mail Politico parasitic-drug-na-ivermectin-bilang- "DOST terminates study on Ivermectin
mistulang kampante ang malaking news/272537826/dost-catanduanes- https://www.bicolmail.net/single- http://politico.ph/ivermectin-clinical- covid19-treatment-sa-ph-hindi-na- in PH
bilang ng mga healthcare workers kaya to-fund-abaca-related-proposals" post/dost-to-fund-abaca-projs-in- trial-in-ph-will-no-longer-push- itutuloy-dost/" May 21
malaking porsiyento pa nila ang hindi catanduanes" through/" CNN Philippines
pa nagpapa booster "Virgin Coconut Oil (VCO) , "Clinical trial ng bansa sa Ivermectin https://www.cnnphilippines.com/
April 26 May 10 "ITDI-MMHRDC to hold webinar | Ang "Ivermectin clinical trial in PH will no bilang COVID-19 treatment, hindi na news/2022/5/21/DOST-terminates-
Umaga Na Balita Na, DZBB" Science For The People, DOSTv" Diaryong Tagalog longer push through itutuloy! - RMN Networks ivermectin-trials-.html"
May 16 May 20 May 21
"DOST deploys 'RxBox' free health "OFWs in Kuwait urged to avail of free Ang Diaryong Tagalog Philippine News Agency RMN "DOST terminates study on Ivermectin
services to Calayan Island - THE telepsychiatry services http://www.diaryongtagalog.net/ https://www.pna.gov.ph/ https://rmn.ph/clinical-trial-ng- in PH
NORTHERN FORUM May 11 agham/itdi-mmhrdc-to-hold-webinar/" articles/1175003" bansa-sa-ivermectin-bilang-covid-19- May 21
April 27 Philippine News Agency treatment-hindi-na-itutuloy/" CNN Philippines
The Northern Forum https://www.pna.gov.ph/ "Qavalo earns DOST project grant "Kuwait OFWS receive https://www.cnnphilippines.com/
https://northernforum.net/dost- articles/1174235" and wins two international awards for telepsychiatriccare through PCHRD- "Clinical trial ng Ivermectin kontra news/2022/5/21/DOST-terminates-
deploys-rxbox-free-health-services-to- innovation supported project COVID-19, naunsyami ivermectin-trials-.html"
calayan-island/" "OFWs in Kuwait urged to avail of free May 18 May 20 May 21
telepsychiatry services - Manila News Sun Star Cebu Health, The Daily Guardian" DWIZ 882 AM "Pag-aaral kaugnay sa Ivermectin
"DOST Vaccine Expert Panel - May 11 https://www.sunstar.com.ph/ "Ivermectin walang epekto sa Covid 19 https://www.dwiz882am.com/index. bilang Covid-19 treatment, tinapos na
Chairperson Dr. Nina Gloriani Manila News article/1929276/cebu/feature/ -- NTF php/clinical-trial-ng-ivermectin-kontra- ng DOST
April 27 http://manilanews.ph/ofws-in-kuwait- qavalo-earns-dost-project-grant-and- May 21 covid-19-naunsyami/" May 21
Sakto, DZMM Teleradyo" urged-to-avail-of-free-telepsychiatry- wins-two-international-awards-for- Abante TNT Bombo Radyo Philippines
services/" innovation" https://tnt.abante.com.ph/ivermectin- "Ivermectin clinical trial in PH will no http://www.bomboradyo.com/pag-
"DOST Vaccine Expert Panel - walang-epekto-sa-covid-19-ntf/" longer push through aaral-kaugnay-sa-ivermectin-bilang-
Chairperson Dr. Nina Gloriani "OFWs in Kuwait urged to avail of free "Panayam kay Dr. Nina Gloriani, May 21 covid-19-treatment-tinapos-na-ng-
April 27 telepsychiatry services Chairperson DOST "Hindi na itutuloy ang clinical trial sa Manila News dost"
Sakto, DZMM" May 12 May 19 Pilipinas ng Ivermectin https://www.manilanews.net/
Philippine Times A.S.P.N, Net 25" May 21 news/272558872/ivermectin-clinical- "DOST ends Ivermectin clinical trials
"DOST strengthens STI ties with https://www.philippinetimes.com/ RMN News Nationwide: The Sound of trial-in-ph-will-no-longer-push- for Covid-19 treatment
Australian institutions news/272547349/ofws-in-kuwait- "DOST Vaccine Expert - Dr. Nina the Nation (12 PM), DZXL" through" May 21
May 1 urged-to-avail-of-free-telepsychiatry- Gloriani Manila Bulletin
Science Sunday, Business Mirror" services" May 19 "Pag-aaral sa Ivermectin itinigil ng "DOST stops Ivermectin clinical trials https://mb.com.ph/2022/05/21/
Straight to the Point, DZXL" DOST May 21 dost-ends-ivermectin-clinical-trials-for-
"DOST strengthens STI ties with "OFWs in Kuwait urged to avail of free May 21 Journal News Online covid-19-treatment/"
Australian institutions | S&T Media telepsychiatry services "DOST umatras sa clinical trial ng Newsroom Weekend, CNN Philippines http://journalnews.com.ph/dost-stops-
Services May 12 Ivermectin TV" ivermectin-clinical-trials/" "DOST umatras sa clinical trial ng
May 1 Philippine Times May 20 Ivermectin
Business MIrror https://www.philippinetimes.com/ Abante Tonite "DOST-VEP Member/Infectious "Ivermectin clinical trial in PH will no May 21
https://businessmirror.com. news/272547349/ofws-in-kuwait- https://tonite.abante.com.ph/ Diseases Expert Dr. Rontgene Solante., longer push through News, Abante Tonite"
ph/2022/05/01/dost-strengthens-sti- urged-to-avail-of-free-telepsychiatry- dost-umatras-sa-clinical-trial-ng- Panibagong Omicron Subvariant na- May 21
tieswith-australian-institutions/" services" ivermectin/" detect ng DOH Philippine Canadian Inquirer "Ivermectin clinical trial in PH will no
May 21 http://canadianinquirer. longer push through
"DOST-Catanduanes to fund abaca- "OFWs in Kuwait urged to avail of free "Ivermectin clinical trial in PH will no Newsroom Weekend, CNN Philippines net/2022/05/21/ivermectin-clinical- May 21
related proposals telepsychiatry services longer push through TV" trial-in-ph-will-no-longer-push- PTV News
May 3 May 12 May 20 through" https://www.ptvnews.ph/ivermectin-
Philippine News Agency Canadian Inquirer Philippine Times "Clinical trial ng kontrobersiyal na Anti- clinical-trial-in-ph-will-no-longer-push-
https://www.pna.gov.ph/ https://canadianinquirer. https://www.philippinetimes.com/ parasitic drug na Ivermectin bilang "PH clinical trial sa Ivermectin, hindi na through/"
articles/1173552" net/2022/05/11/ofws-in-kuwait-urged- news/272558872/ivermectin-clinical- COVID19 treatment sa PH, hindi na itutuloy!
to-avail-of-free-telepsychiatry-services" trial-in-ph-will-no-longer-push-through" itutuloy – DOST May 21 "Ivermectin, wala talagang bisa vs
"DOST-Catanduanes to fund abaca- May 21 Remate Online COVID-19 - eksperto - RMN Networks
related proposals "DOST to fund abaca projs in "Ivermectin Clinical Trial In PH Will No Bombo Radyo Philippines https://www.remate.ph/ph-clinical- May 22
 276 PCHRD ANNUAL REPORT 2022 ANNEXES 277

RMN May 23 "Mga pag-aaral kaugnay sa bisa at May 24 Concludes Webinar on Food, Nutrition, news/272565611/dost-chief-hopes-for-
https://rmn.ph/ivermectin-wala- Philippine Daily Inquirer kaligtasan ng paggamit ng Ivermectin Umaga Na Balita Na, DZBB" Health, and Safety passage-of-psto-act"
talagang-bisa-vs-covid-19-eksperto/" https://newsinfo.inquirer.net/1601172/ sa mga pasyenteng may COVID-19, May 27
govt-stops-clinical-trials-of-ivermectin" ipinatigil na ng DOST "Mga pag-aaral hinggil sa bisa at Happening PH "Provincial S&T Office bill passes
"Ivermectin has no evidence of May 23 kaligtasan ng paggamit ng anti- http://happeningph.com/ Senate's final reading
beneficial effects on COVID patients, "DOST ends study of ivermectin for 24 Oras, DZBB" parasitic drug na Ivermectin, ipinatigil food-security-health-more- May 29
says NTF adviser COVID-19 na ng Dept. of Science and Technology important-post-pandemic-itdi- Science Sunday, Business Mirror"
May 22 May 23 "Ivermectin, walang bisa laban sa May 24 mmhrdc-concludes-webinar-on-food-
Politics ABSCBN News Covid-19 ayon kay Ted Herbosa Melo Del Prado sa Super Radyo, nutrition-health-and-safety/" "DOST funds COVID-19 vaccine
http://politics.com.ph/ivermectin-has- https://news.abs-cbn.com/ May 23 DZBB" immune response study
no-evidence-of-beneficial-effects-on- news/05/23/22/dost-ends-study-of- Ratsada sa Umaga, DWIZ" "DOST Chief Hopes For Passage Of May 30
covid-patients-says-ntf-adviser/" ivermectin-for-covid-19" "MTek opens new unit to produce test PSTO Act | The Luzon Daily Philstar
"Ivermectin, walang bisa laban sa kits for Covid, other illnesses | Roderick May 27 https://www.philstar.com/
"DOST, itinigil na ang pag-aaral sa "DOST tinigil clinical trial ng Ivermectin Covid-19 ayon kay Ted Herbosa Abad The Luzon Daily headlines/2022/05/30/2184622/
ivermectin vs COVID-19 May 23 May 25 http://theluzondaily.com/dost-chief- dost-funds-covid-19-vaccine-immune-
May 22 May 23 Balitang Todo Lakas, DWIZ" Business Mirror hopes-for-passage-of-psto-act/" response-study"
Mega Balita Linggo, DZRH AM" News Ko https://businessmirror.com.
https://newsko.com.ph/2022/05/23/ "PH, Iran to pursue collab on sci-tech, ph/2022/05/25/mtek-opens-new-unit- "University of San Agustin in Iloilo "DOST funds COVID-19 vaccine
"Pag-aaral sa ivermectin, itinigil na dost-tinigil-clinical-trial-ng-ivermectin- innovation to-produce-test-kits-for-covid-other- boosts role as PH's hub for medicine immune response study
May 22 vs-covid-19/" May 23 illnesses/" discovery, public health research May 30
Sunday Updates, DZRH AM" Philippine News Agency May 27 MSN Philippines
"Clinical trial ng Ivermectin bilang https://www.pna.gov.ph/ "MTek opens new unit to produce test Manila Bulletin https://www.msn.com/en-ph/news/
"DOST, itinigil na ang pag-aaral sa gamot sa Covid-19 sa Phl, hindi na articles/1175111" kits for Covid, other illnesses https://mb.com.ph/2022/05/27/ national/dost-funds-covid-19-vaccine-
ivermectin itutuloy May 26 university-of-san-agustin-in-iloilo- immune-response-study/ar-AAXRcYT"
May 22 May 23 "Clinical trial ng ivermectin, hindi na Health and Fitness, Business Mirror" boosts-role-as-phs-hub-for-medicine-
Mega Balita Linggo, DZRH TV" Rise and Shine Pilipinas, PTV 4" itutuloy discovery-public-health-research/" "DOST organizes first S&T Fellows
May 23 "PAGKAIN, NUTRISYON, KALUSUGAN convention, seeks to reinforce agency's
"Pag-aaral sa ivermectin, itinigil na "Mga pag-aaral kaugnay sa bisa at TEKA TEKA ALAS 4:30 NA!, DWIZ" AT KALIGTASAN | Ang Diaryong "DOST trials: VCO helps mild Covid-19 workforce
May 22 kaligtasan ng paggamit ng Ivermectin Tagalog cases recover faster May 31
Sulong Pilipinas, DZRH TV" sa mga pasyenteng may COVID-19, "PH, Iran to pursue collab on sci-tech, May 26 May 28 Manila Bulletin
ipinatigil na ng DOST innovation Ang Diaryong Tagalog Sun Star Davao https://mb.com.ph/2022/05/31/dost-
"Ivermectin, walang bisa laban May 23 May 24 http://www.diaryongtagalog.net/ https://www.sunstar.com.ph/ organizes-first-ss-workforce/"
COVID-19 -- NTF Special adviser 24 Oras, GMA 7" Philippine Times agham/pagkain-nutrisyon-kalusugan- article/1930304/davao/local-news/
May 22 https://www.philippinetimes.com/ at-kaligtasan/" dost-trials-vco-helps-mild-covid-19- "Member, DOST Vaccine Experts Panel
DWIZ 882 AM "Pag-aaral sa paggamit ng ivermectin news/272561515/ph-iran-to-pursue- cases-recover-faster" Dr. Rontgene Solante- Panahon na
https://www.dwiz882am.com/index. vs Covid-19, ipinatigil na ayon sa NTF collab-on-sci-tech-innovation" "PH, US science fellow explore possible para i-lift ang state of emergency para
php/ivermectin-walang-bisa-ntf- vs Covid-19 collab on ASF diagnostics "42 Municipalities in NorMin to benefit sa COVID-19
special-adviser/" May 23 "Gamot na ivermectin sa Covid-19, May 26 from advanced healthcare devices June 1
Good Morning Kuya, UNTV" walang bisa Philippine News Agency fromDOST - Business Week Mindanao Frontline Tonight, TV 5"
"DOST ends Ivermectin clinical trials "DOST itinigil na ang clinical trials sa May 24 https://www.pna.gov.ph/ May 28
May 22 Ivermectin Kada Umaga, Net 25" articles/1175263" Business Week Mindanao "Panayam kay Vaciine Expert Panel,
National News, Manila Bulletin" May 23 https://businessweekmindanao. Infectious Disease Expert, Dr. Rontgene
Headline Pilipinas, DZMM Teleradyo" "Mga pag-aaral hinggil sa bisa at "DOST chief hopes for passage of com/42-municipalities-in-normin-to- Solante
"DOST stops Ivermectin clinical trials kaligtasan ng paggamit ng anti- PSTO Act benefit-from-advanced-healthcare- June 3
May 22 "Gamot na ivermectin sa COVID-19, parasitic drug na Ivermectin, ipinatigil May 26 devices-fromdost/" Tutok Tulfo, DZRB"
News, Peoples Tonight" walang bisa - NTF na ng Dept. of Science and Technology Philippine News Agency
May 23 May 24 https://www.pna.gov.ph/ "DOST chief hopes for passage of "DOST funds research on effectiveness
"GOV'T STOPS CLINICAL TRIALS OF Mata ng Agila, Net 25" Melo Del Prado sa Super Radyo, articles/1175259" PSTO Act of Valencia City Drug Rehabilitation
IVERMECTIN GMANEWSTV" May 28 program
May 23 "DOST itinigil na ang clinical trials sa "Food Security, Health More Important Philippine Times June 5
News, Philippine Daily Inquirer" Ivermectin "Ipinatigil na ng DOST ang mga pag- Post-Pandemic: ITDI-MMHRDC https://www.philippinetimes.com/ Philippine Information Agency
May 23 aaral hinggil sa bisa at kaligtasan sa
"Gov't stops clinical trials of ivermectin Headline Pilipinas, DZMM" paggamit ng Ivermectin
 278 PCHRD ANNUAL REPORT 2022 ANNEXES 279

https://pia.gov.ph/press- "Call for applications: Gelia Castillo headlines/2022/06/16/2188644/ Preservative Gets DOST Backing | The Philippine Post "Use of nanotexturing eyed to make knee implant safer
releases/2022/06/05/dost-funds- Award for Research on Social chicken-prices-up-da-blames-low- June 17 June 17
research-on-effectiveness-of-valencia- Innovations in Health production" The Philippine Post Manila News
city-drug-rehabilitation-program" June 14 https://thephilippinepost.com/study-on-durian-as-natural- https://www.manilanews.net/news/272589281/use-of-
Rappler "Study on durian as natural preservative-gets-dost-backing/" nanotexturing-eyed-to-make-knee-implant-safer "
"Balik scientist, DOST eyes affordable https://www.rappler.com/bulletin- preservative gets DOST backing
gold-standard ASF test kits for PH board/call-for-applications-gelia- June 16 "Use of nanotexturing eyed to make knee implant safer "SPMC gets P1-M fund for kidney transplant research
farmers, vaccine to help eradicate ASF castillo-award-research-social- Philippine Times June 17 June 17
June 6 innovations-health/" https://www.philippinetimes.com/ Philippine Times Manila News
CNN Philippines news/272588006/study-on-durian- https://www.philippinetimes.com/news/272589281/use-of- https://www.manilanews.net/news/272589219/spmc-gets-
https://www.cnnphilippines.com/ "BusinessMirror receives DOST as-natural-preservative-gets-dost- nanotexturing-eyed-to-make-knee-implant-safer" p1-m-fund-for-kidney-transplant-research"
news/2022/6/6/dost-asf-homer- 'Science for the People' awards | backing"
pantua-ronnie-de-castro.html" BusinessMirror "Study On Durian As Natural Preservative Gets DOST "P300-K cash prize at stake for top health research
June 14 "Study on durian as natural Backing | The Visayas Journal innovation
"DOST funds research on effectiveness Business Mirror preservative gets DOST backing June 17 June 17
of Valencia City drug rehab program - https://businessmirror.com. June 16 The Visayas Journal Manila News
Business Week Mindanao ph/2022/06/14/businessmirror- Manila News https://thevisayasjournal.com/study-on-durian-as-natural- https://www.manilanews.net//news/272588345/p300-k-
June 9 receives-dost-science-for-the-people- https://www.manilanews.net/ preservative-gets-dost-backing/" cash-prize-at-stake-for-top-health-research-innovation"
Business Week Mindanao awards/" news/272588006/study-on-durian-
https://businessweekmindanao.com/ as-natural-preservative-gets-dost- "Study On Durian As Natural Preservative Gets DOST "Kit being developed for cheaper, faster enteric virus
dost-funds-research-on-effectiveness- "BusinessMirror receives DOST backing" Backing | Manila Magazine detection
of-valencia-city-drug-rehab-program/" 'Science for the People' awards - June 17 June 17
PinoyFeeds "DOST Gabi ng Parangal at Manila Magazine Philippine Times
"UPMIN-MCM RESEARCH GETS June 15 Pasasalamat https://mnlmag.com/study-on-durian-as-natural- https://www.philippinetimes.com/news/272589464/kit-
AWARD FROM DOST Pinoy Feeds June 16 preservative-gets-dost-backing/" being-developed-for-cheaper-faster-enteric-virus-detection"
June 10 http://pinoyfeeds.com/businessmirror- The Scoop, CNN Philippines TV"
Billboard, Sun Star Davao" receives-dost-science-for-the-people- "Study On Durian As Natural Preservative Gets DOST "Kit being developed for cheaper, faster enteric virus
awards-2/" "DOST Gabi ng Parangal at Backing | Woman.ph detection
"DOST S&T Fellows: A mechanism Pasasalamat June 17 June 17
to ensure supply of Filipino scientific "BusinessMirror receives DOST June 16 WomanPH Manila News
experts in PHL 'Science for the People' awards | The Scoop, CNN Philippines TV" https://woman.ph/study-on-durian-as-natural-preservative- https://www.manilanews.net/news/272589464/kit-being-
June 12 BusinessMirror gets-dost-backing/" developed-for-cheaper-faster-enteric-virus-detection"
Science Sunday, Business Mirror" June 15 "DOST Gabi ng Parangal at
Business Mirror Pasasalamat "Study On Durian As Natural Preservative Gets DOST "Enteric viruses detection kit being developed
"DOST S&T Fellows: A mechanism https://businessmirror.com. June 16 Backing | The Mindanao Life June 17
to ensure supply of Filipino scientific ph/2022/06/15/businessmirror- The Scoop, CNN Philippines TV" June 17 Manila News
experts in PHL - Manila News receives-dost-science-for-the-people- The Mindanao Life https://www.manilanews.net/news/272589362/enteric-
June 12 awards-2/" "DOST eyes local S&T experts to be https://themindanaolife.com/study-on-durian-as-natural- viruses-detection-kit-being-developed"
Manila News more directly involved in policy and preservative-gets-dost-backing/"
http://manilanews.ph/dost-st-fellows- "Chicken prices up; DA blames low decision making "Enteric viruses detection kit being developed
a-mechanism-to-ensure-supply-of- production June 17 "Study On Durian As Natural Preservative Gets DOST June 17
filipino-scientific-experts-in-phl/" June 16 Philippine Information Agency Backing | PAGEONE Philippine Times
"Member, Vaccine Expert Panel News, Philippine Star" https://pia.gov.ph/press- June 17 https://www.philippinetimes.com/news/272589362/enteric-
, Infectious Diseases Expert Dr. releases/2022/06/17/ Page One viruses-detection-kit-being-developed"
Rontgene Solante "Chicken prices up; DA blames low dost-eyes-local-st-experts- https://pageone.ph/study-on-durian-as-natural-
June 13 production to-be-more-directly-involved-in-policy- preservative-gets-dost-backing/" "Enteric viruses detection kit being developed
Public Briefing Laging Handa June 16 and-decision-making" June 17
Philippines, PTV 4" Philstar "USeP's study on durian as natural preservative gets DOST Manila News
https://www.philstar.com/ "Study On Durian As Natural backing https://www.manilanews.net//news/272589362/enteric-
June 17 viruses-detection-kit-being-developed"
Edge Davao
http://edgedavao.net/latest-news/2022/06/17/useps-study- "DOST Gabi ng parangal at pasasalamat
on-durian-as-natural-preservative-gets-dost-backing/" June 17
 280 PCHRD ANNUAL REPORT 2022 ANNEXES 281

The Scoop, CNN Philippines TV" "Recognition, thanksgiving for DOST June 23 2022-un-public-service-awards/" "DOST’s S4CP is ‘game changer’ in "DOST immortalizes hard word in 5
" partners | TFA Commercial Realty - Journal News Online "The Science for Change Program' ng PHL innovation 'legacy' books
Kit being developed for cheaper, faster CORFAC International http://journalnews.com.ph/dost- DOST, wagi ng 2022 United Nations June 26 July 3
enteric virus detection June 19 science-for-change-wins-most- Public Service Awards Science Sunday, Business Mirror" Science Sunday, Business Mirror"
June 17 TFA Commercial Realty prestigious-intl-award-in-public- June 23
Manila News http://tfa.ph/recognition-thanksgiving- service/" Rise and Shine Pilipinas, PTV 4" "DOST's S4CP is 'game changer' in "DOST immortalizes hard word in 5
https://www.manilanews.net// for-dost-partners/" PHL innovation | Lyn Resurreccion 'legacy' books | Lyn Resurreccion
news/272589464/kit-being- "DOST's science program wins in UN "PH's Science for Change Program June 26 July 3
developed-for-cheaper-faster-enteric- "DOST@64 confers Science for the Public Service Award wins UN Public Service Award Business Mirror Business Mirror
virus-detection" People awards to partners | Lyn June 23 June 23 https://businessmirror.com. https://businessmirror.com.
Resurreccion Sun Star Davao Philippine News Agency ph/2022/06/26/dosts-s4cp-is-game- ph/2022/07/03/dost-immortalizes-
"Study on durian as natural June 19 https://www.sunstar.com.ph/ https://www.pna.gov.ph/ changer-in-phl-innovation/" hard-work-in-5-legacy-books/"
preservative gets DOST backing Business Mirror article/1932937/davao/local-news/ articles/1177376"
June 17 https://businessmirror.com. dosts-science-program-wins-in-un- "DOH predicts rise in daily Covid-19 "DOST immortalizes hard word in 5
Top Stories, Sun Star Davao" ph/2022/06/19/dost64-confers- public-service-award" "DOST's Science for Change Program cases next month | Claudeth Mocon- 'legacy' books - PinoyFeeds
science-for-the-people-awards-to- one of 10 recipients of 2022 UN Public Ciriaco July 3
"DOST Gabi ng parangal at partners/" "UN lauds DOST's 'Science for Change' Service Awards June 28 Pinoy Feeds
pasasalamat program June 24 Business Mirror http://pinoyfeeds.com/dost-
June 18 "USEP GETS FUNDING FOR DURIAN June 23 National News, Manila Bulletin" https://businessmirror.com. immortalizes-hard-word-in-5-legacy-
The Scoop, CNN Philippines TV" PRESERVATIVE PROJECT ABSCBN News ph/2022/06/28/doh-predicts-rise-in- books/"
June 20 https://news.abs-cbn.com/ "DOST-Science for Change Program dailycovid-19-cases-next-month/"
"DOST hopeful more 'balik scientists' The Post news/06/23/22/un-lauds-dosts- wins 2022 UN Public Service Awards "DOST immortalizes hard work in 5
will come home during Marcos Jr. https://thepost.net.ph/news/campus/ science-for-change-program" June 24 "Member VEP, Infectious Diseases 'legacy' books | Lyn Resurreccion
admin - PinoyFeeds usep-gets-funding-for-durian- 2nd Front Page, Business Mirror" Expert Dr. Rontgene Solante July 3
June 18 preservative-project/" "DOST's Science for Change Program June 28 Business Mirror
Pinoy Feeds one of 10 recipients of 2022 UN Public "DoST's Science for Change program Public Briefing Laging Handa https://businessmirror.com.
http://pinoyfeeds.com/dost-hopeful- "KIT PARA SA MURA, MABILIS NA Service Awards bags UN award Philippines, PTV 4" ph/2022/07/03/dost-immortalizes-
more-balik-scientists-will-come-home- VIRUS DETECTION INAARAL June 23 June 24 hard-work-in-5-legacy-books/"
during-marcos-jr-admin/" June 21 Manila Bulletin News, Manila Times" "DOH predicts rise in daily Covid-19
Lifestyle, Abante" https://mb.com.ph/2022/06/23/dosts- "DOST PROGRAM WINS UN AWARD cases next month "COA flags UP for failing to utilize P53
"Local researchers develop cheaper science-for-change-program-one- June 24 June 29 million funds for COVID-19 projects
enteric virus detection kit "DOST-Science for Change Program of-10-recipients-of-2022-un-public- News, Philippine Daily Inquirer" The Nation, Business Mirror" July 8
June 18 wins 2022 UN Public Service Awards | service-awards/" Philippine Star
Metro News Central BusinessMirror "DoST's Science for Change program "PH's first DRRM in Health Center https://www.philstar.com/
http://metronewscentral.net/in-and- June 23 "PH's Science for Change Program bags UN award launched headlines/2022/07/08/2194000/coa-
around-the-metro/local-researchers- Business Mirror wins UN Public Service Award June 24 July 1 flags-failing-utilize-p53-million-funds-
develop-cheaper-enteric-virus- https://businessmirror.com. June 23 The Manila Times The Manila Times covid-19-projects"
detection-kit" ph/2022/06/23/dost-science-for- Philippine Times https://www.manilatimes. https://www.manilatimes.
change-program-wins-2022-un-public- https://www.philippinetimes.com/ net/2022/06/24/news/national/dosts- net/2022/07/01/news/national/ "UPS has P61-M unutilized project
"Recognition, thanksgiving for DOST service-awards-2" news/272596158/ph-science-for- science-for-change-program-bags-un- phs-first-drrm-in-health-center- funds from 3 agencies, says COA
partners change-program-wins-un-public- award/1848454" launched/1849311" July 8
June 19 "DOST's science program wins UN service-award" Manila Bulletin
Science Sunday, Business Mirror" Public Service Award "DOST program wins UN Award "PH's first DRRM in Health Center https://mb.com.ph/2022/07/08/ups-
June 23 "DOST Science Program Achieves June 24 launched has-p61-m-unutilized-project-funds-
"Recognition, thanksgiving for DOST Sun Star Davao Milestone, Wins 2022 UN Public Philippine Daily Inquirer July 1 from-3-agencies-says-coa/"
partners | Lyn Resurreccion https://www.sunstar.com.ph/ Service Awards - SDN - Science & https://newsinfo.inquirer.net/1615779/ News, Manila Times"
June 19 article/1932942/davao/local-news/ Digital News dost-program-wins-un-award" "Mas katakot ang dengue kaysa
Business Mirror dosts-science-program-wins-un- June 23 "Panayam kay Dr. Nina Gloriani , DOST- COVID-19?
https://businessmirror.com. public-service-award" Scitech and Digital News "Study on durian as natural VEP Chairman July 13
ph/2022/06/19/recognition- https://scitechanddigital. preservative gets DOST backing July 1 Abante Tonite
thanksgiving-for-dost-partners/" "DOST- Science for Change wins most news/2022/06/23/dost-science- June 24 Dobol Weng Sa Dobol B, DZBB" https://tonite.abante.com.ph/mas-
prestigious int'l award in public service program-achieves-milestone-wins- Lifestyle, Mindanao Today" katakot-ang-dengue-kaysa-covid-19/"
 282 PCHRD ANNUAL REPORT 2022 ANNEXES 283

"App to detect depression among Covid patients being Finance and Administrative Division (FAD) Diez, Phoebe R. Noble, Christine Rae Simone D.
developed Atienza, Michelle V. (Chief) Escal, Charlene A. Obdosantos, Roi Miguel M.
July 13 Agsaoay, Donna Mae J. Gonzales, Audrey John P. Olaguer, Louise Sky T.
Philippine Times Alvarez, Ryan Gozun, Ian Hannah C. Pacho, Mary Ann I.
https://www.philippinetimes.com/news/272618846/app-to- Baclas, Ric Fuentes Jimenez, Maria Rexie Parilla, Patricia Mae
detect-depression-among-covid-patients-being-developed" Bodo Jr, Bonifacio Benedict Juanite, Ma. Katrina G. Quirante, Jason
Buclatin, Jessamyn M. Labonite, Laila Molina Salaysay, Chiendy Mae F.
"App to detect depression among Covid patients being Cabael, Ronafe Lanuza, Maria Angelica D. Sanchez, Claridel H.
developed Carullo, Aljon T. Maza, Daphne Joyce Sarmiento, Lance Ehrold D.
July 13 Coleto, Janneth M. Miranda, Pamela Joyce L. Serrano, Yasmin Janina A.
Manila News Dayao, John Jefferson G. Panganiban, Fatima E. Solis, Abby Gail
https://www.manilanews.net/news/272618846/app-to- Dela Cruz, Berwyn John C. Pedraza, Alysya Marie Dizon Talag, Maica Ann A.
detect-depression-among-covid-patients-being-developed" Esquejo, Benedict Leondro V. Perez, Rubee Ellaine C. Tumlos, Pearl Kathleen C.
Faller, Kyla Maria Ravago, Analyn M. Valdez, Joseph Emmanuel
"App to detect depression among Covid patients being Flores, Faye A. Refuerzo, Reichel Ann P.
developed Francisco, Arsenia D. Roja, Lucila Espiritu Research Information, Communication, and Utilization
July 13 Go, Lorainne M. Suerte, Jessica Marie R. Division (RICUD)
Manila News Gonzales, Alec Benjamin M. Taculog, Sydney P. Garcia, Ullyann C. (Chief)
https://www.manilanews.net//news/272618846/app-to- Hernandez, Diego O. America, Joana A.
detect-depression-among-covid-patients-being-developed" Inocencio, Kristine N. Research and Development Management Division Arcaina, Jaobly B. *
Laureano, Eric B. (RDMD) Bacarra, Alyana Kaye M.
"How The Medical City and the PCHRD are creating the Lupango, Evelyn A. De Leon, Paul Ernest N. (Chief) Balangat, Julie Anne G.
next leaders of healthcare research Manuel, Crisel Joie T. Agapito, Renzo Val G. Banal, Mary Joy
July 16 Marabe, John Jave D. Almonte, Andrea Mae L. Bigay, Giselle Gale P.
Philippine Daily Inquirer Martinez, Gerlie P. Ambrocio, Diovelle Anne Eve E. Cenon, Grace Ann A.
https://business.inquirer.net/353035/how-the-medical-city- Mercado, James Lloyd T. Austria, Jemuel Joshua Z. Daulat, Grace Ruth
and-the-pchrd-are-creating-the-next-leaders-of-healthcare- Milante, Earvin James P. Bartolome, Jay Vee C. Dimailig, Catherine Joy C.
research" Milante, Irish G. Buan, Raizsa Sharmi E. Flores, Donavie D.
Ocon, Sylvia N. Bulao, Melissa C. Gabriel, Ross Gerald T.
Ogsimer, Franco Bungalon, Kamzky Jonas P. Gonzalez, Christine Jane M.

List of Personnel Pambid, Kateleen A. Cababa, Georgina Rae C. Hasta, Marc Enrico O.
Pangan, Cirio Jr. D. Campos, Mary Charlene R. Hernandez, Joanna Mae D.
Paulican, Donna Dominique F. Celebrado, Jules Carl Intia, Maria Violeta G.
(As of 31 December 2022)
Pedrezuela, Ronaldo P. Cepria, Deborah Joy J. Itulid, Ana Ciaren H.
Quiminales, Desiree S. Dalugdog, Arnestie F. Labutong, Karen Joy A.
Office of the Executive Director (OED) Ruga, Erving B. David, Maria Ariane Agatha Victoria B. Lavapie, Neil Jerome P.
Montoya, Jaime C. (Executive Director) Sacro, Glaiza D. De Jesus, Ana Jessa A. Limbo, John Paul G.
Manalo, Eliza D. Sacro, Louie Vic N. De Mesa, Nheka Louise D. Lolong, Ronald Ryan D.
Metille, Rizalina M. Saguin, Arnold S. Decena, Patricia Mae T. Macan, Jwynne Gwyneth P.
Tumlos, Vincent John H. Taborda, Wilfredo T. Depatillo, John Philip P. Marco, Mylene B.
Tolentino, Jonavie Dizon, Louise Nicole N. Mendez, Nowell
Assistant Scientists Zacarias, Orlando Echaluse, Izobelle E. Molina, Ronel D.
Malabad, John Carlo Zepeda, Chezca Stephanie V. Forteza, Marfil F. Oriane, Aileen A.
King, Ruby Anne Gelera, Guidditta L. Pantaleon, Cris E.
Institution Development Division (IDD) Gutierrez, Renmar Joseph I. Pariño, Renzell Ann M.
S&T Fellows De Leon, Paula Jane A. (OIC) Landingin, Angela Joy D. Pimentel, Geraldine Bea P.
Alcudia-Catalma, Ma. Neda Alegrado, Mercy Mae E. Laya, Marianne Joy G. Ramirez, Shaira Ingrid G.
Aman, Aimee Yvonne Criselle Arenas, Eixylaine O. Lim, Geraldine Bernadete C.S. Regio, Angelique R.
Calpito, Karell Jo Angelique C. Baculina, Renalyn H. Lo, Nica D. Rico, Elimel Rome A.
Dumbrique, Jakov Ivan Balbuena, Maria Belen A. Lobete, Ma. Anne L Sumague, Marie Antoniette V.
Jimenez, Sarah Jane Cambonga, John Marc R. Macasinag, Angeline S. Tiamson, John Henry B.
Perez, Phoebe Nicole Caro, Agape Joy Mendoza, Ana Veronica C. Uy, Alyne Nicole Jake M.
Rosana, Albert Castelo, Estelle Kathleen B. Mendoza, Rachelle C. Vios, Christian Anthony B.
QUALITY POLICY
We are committed to provide research-based solutions and innovations in health, based on the balance scorecard set by the
Council, within the highest standards of professionalism, within our core competency and available resources, in accordance
to customer requirements, and in adherence to ethical standards, applicable regulatory and statutory requirements.

We commit to continually improve the effectiveness of our QMS to enhance customer satisfaction.
286 PCHRD ANNUAL REPORT 2022

PCHRD
ANNUAL REPORT

20
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Gen. Santos Ave., Bicutan, Taguig City 1631 Philippines
Telephone: (+632) 8-837-7534 to 37
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