Genesis of Cabot Rings
Genesis of Cabot Rings
Cabot Rings
ABHIJITH S P
CVAS POOKODE
INTRODUCTION
• Cabot rings are thin, red-violet staining, threadlike strands in
the shape of a loop or figure-8 that are found on rare occasions
in red blood cells (erythrocytes).
• They are believed to be microtubules that are remnants from
a mitotic spindle, and their presence indicates an abnormality in
the production of red blood cells.
• Cabot Rings, considerably rare findings, when present are
found in the cytoplasm of red blood cells and in most cases, are
caused by defects of erythrocytic production and are not
commonly found in the blood circulating throughout the body.
• Cabot rings appear as ring, figure-8 or loop-shaped structures
on microscopy.
• Cabot rings stain red or purple with Wright's stain.
• Cabot rings have been observed in a handful of cases in
patients with pernicious anemia, lead poisoning, certain other
disorders of red blood cell production (erythropoiesis).
• They were first described in 1903 by
American physician, Richard Clarke Cabot (1868-1939).
A-CABOT RINGS
B-HOWELL JOLLY BODIES