ProFound AI®

for Digital Breast Tomosynthesis

Discover the ProFound impact of our unrivaled Patient Benefits:

3rd generation artificial intelligence for digital breast Assists in early detection, which
tomosynthesis1 can lead to improved outcomes

Reading digital breast tomosynthesis (DBT) cases means being able to accu- Reduces false positives/recalls
rately interpret extensive amounts of data. Clinicians are confronted by the
Improves detection accuracy
workload and time required to accurately read the data contained in DBT cases.

ProFound AI® is raising the bar on detection performance. It is a high-perform- Facility Benefits:
ing, concurrent-read, cancer-detection and workflow solution that rapidly and
Enhances patient care with
accurately analyzes each tomosynthesis image, detecting both malignant soft
improved detection technology
tissue densities and calcifications with unrivaled accuracy.
Improves workflow efficiency
ProFound AI is proven to offer superior clinical performance2 Increases diagnostic confidence

Supports mixed tomosynthesis

environments

8% improvement in 7% reduction in rate 52.7% reduction in reading Visit icadmed.com

sensitivity of recalls time for radiologists to request a demo

ProFound AI 3rd generation performance1,3

Up to 10% specificity Up to 1% improvement Up to 40% faster

performance improvement in sensitivity processing

How does ProFound AI work?

The ProFound AI algorithm rapidly and accurately analyzes each individual
image or slice and identifies potentially malignant lesions. Trained with one
of the largest available 3D image datasets, ProFound AI provides radiologists
with crucial information, such as lesion Certainty of Finding and Case Scores,
which assists in prioritizing caseload, clinical decision-making and may help to
reduce physician burnout.
www.icadmed.com
1.866.280.2239

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ProFound AI is FDA cleared to offer superior Case Score
performance and sensitivity to support radiologists
in the fight against breast cancer with an unrivaled Case Scores are assigned to each case by the ProFound AI
accuracy of detection. algorithm. The Case Score represents how confident the
algorithm is that a case is malignant. All cases, including
Certainty of Finding and Case Scores those without detections, will be assigned a Case Score.
Clinicians may use this Case Score information to gain
The ProFound AI algorithm is trained to detect malignant a sense of case complexity, which may be useful for
soft tissue densities and calcifications. Certainty of prioritizing the reading worklist if supported by the
Finding and Case Scores are assigned to each detection specific worklist provider.
and each case respectively. Certainty of Finding and Case
Scores are relative scores computed by the ProFound AI Platform
algorithm and represent the algorithm’s confidence that
a detection or case is malignant. ProFound AI runs on
the industry-leading
The scores are represented on a 0% to 100% scale. A PowerLook® server platform
higher score indicates a higher level of confidence in with NVIDIA® Graphical
the malignancy of the detection or case. The Certainty Processing Units (GPU),
of Finding and Case Scores serve as a guide to the the latest in powerful GPU
interpreting radiologist to aid in determining if a technology. PowerLook
suspicious finding or case needs further workup. is a flexible and reliable
DICOM platform that easily
Certainty of Finding Score integrates with image
modalities, mammography
Certainty of Finding Scores are assigned to each
review workstations, PACS,
detection identified by the ProFound AI algorithm. The
and image storage systems.
score represents how confident the algorithm is that
Leveraging the latest in GPU
the detection is malignant. Certainty of Findings scores
technology, the algorithm can rapidly process a 4-view
assist in prioritizing caseload and clinical decision-
tomosynthesis case, ensuring results are available to
making.
radiologists in the most efficient manner.

Examples with Certainty of Finding Scores for

Soft Tissue Density Detections

85% Certainty of Finding 48% Certainty of Finding

Examples with Certainty of Finding Scores for

Calcification Detections

References:
1. iCAD data on file. FDA filing: K203822. Standalone performance varies by vendor. FDA
Cleared and CE Mark Pending.
2. Conant, E et al. (2019). Improving Accuracy and Efficiency with Concurrent Use of
97% Certainty of Finding 43% Certainty of Finding Artificial Intelligence for Digital Breast Tomosynthesis. Radiology: Artificial Intelligence. 1
(4). Accessed via https://pubs.rsna.org/doi/10.1148/ryai.2019180096
3. Compared to previous versions of the software, the ProFound AI 3.0 algorithm
offers up to a 10% improvement in specificity performance, up to 1% improvement in
sensitivity, and up to 40% faster processing on the new PowerLook platform.

© iCAD, Inc. All rights reserved. iCAD, the iCAD logo, PowerLook and ProFound are registered trademarks of iCAD, Inc. Reproduction of any
of the material contained herein in any format or media without the express written permission of iCAD, Inc. is prohibited.
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