Pre Eclampsia
Pre Eclampsia
U N I T 2: O B S T E T R I C S
SECTION B: ABNORMAL OBSTETRICS
Rationale: Preeclampsia-eclampsia accounts for significant morbidity and mortality in both the mother and newborn.
TEACHING CASE
CASE: An 18 year old G1P0 currently at 38 0/7 weeks presents for her routine prenatal visit. She has had an uncompli-
2
cated pregnancy up to this point, with the exception of a late onset of prenatal care and obesity (BMI of 35 kg/m ). She
reports that during the past week, she has noted some swelling of her hands and feet. She also has been feeling a bit
more fatigued and has had a headache on and off. She reports good fetal movement. She has had some contractions on
and off, but nothing persistent. Her blood pressure is 147/92 and her urine dip has 1+ protein/no ketones/no glucose.
The fundal height measures 36 cm, the fetus is cephalic with a heart rate of 144 bpm. On physical exam you note that
the patient has 3+ pre-tibial edema, and trace edema of her hands and face. She has 2+ deep tendon reflexes and 2 beats
of clonus. You review her blood pressures up to this point and note that at the time of her first prenatal visit at 18
weeks, her blood pressure was 130/76 and she had no protein in her urine. However, since that visit, her blood pres-
sures seem to have been climbing higher with each visit. Her last visit was one week ago, and she had a blood pressure
of 138/88 with trace protein in the urine and she has gained 5 pounds.
TH
APGO MEDICAL STUDENT EDUCATIONAL OBJECTIVES, 10 EDITION
TEACHING CASES
3. How does the physiology of preeclampsia lead to the clinical symptoms and findings?
4. What are the laboratory findings that support a diagnosis of preeclampsia-eclampsia syndrome?
5. What types of maternal and fetal complications are associated with preclampsia-eclampsia syndrome?
REFERENCES
Beckman CRB, et al. Obstetrics and Gynecology. 7th ed. Philadelphia: Lippincott, Williams & Wilkins, 2013.
Hacker NF, Moore JG, et al. Essentials of Obstetrics and Gynecology. 5th ed. Philadelphia: Saunders, 2010.
Sibai B. Diagnosis and Management of Gestational Hypertension and Preeclampsia. ObstetGynecol. High-Risk Preg-
nancy Series: An Expert's View. Jul 2003; (102) 1 - p 181-192.
Lain KY, Roberts JM. Contemporary concepts of the pathogenesis and management of preeclampsia. JAMA. Jun
26 2002; 287(24):3183-6.